Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_053609624.1	6	Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122	"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis"
XP_053616284.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053615614.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053614014.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053624521.1	26	Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-389977;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-8955332	"Gap junction assembly";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Post-chaperonin tubulin folding pathway";"RHO GTPases activate IQGAPs";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin"
XP_053619420.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_053624508.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053602658.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053620596.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053599951.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_053623716.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053602410.1	6	Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840	"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Rho GTPase cycle"
XP_053621128.1	5	Reactome: R-HSA-171007;Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097;Reactome: R-HSA-168638	"p38MAPK events";"DSCAM interactions";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"NOD1/2 Signaling Pathway"
XP_053612087.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_053603447.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497	"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_053605965.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053609473.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_053620765.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_053611700.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053625546.1	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
XP_053606946.1	56	Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257	"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"UCH proteinases";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Degradation of AXIN"
XP_053622546.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_053616699.1	8	Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-165159;Reactome: R-HSA-380972	"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Neutrophil degranulation";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_053616409.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_053609184.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434	"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053607877.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_053622513.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053599679.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053606913.1	17	KEGG: 00240+2.4.2.1;MetaCyc: PWY-5695;MetaCyc: PWY-4202;MetaCyc: PWY-5532;MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;MetaCyc: PWY-6644;KEGG: 00230+2.4.2.1;Reactome: R-HSA-74217;MetaCyc: PWY-6609;MetaCyc: PWY-6627;KEGG: 00760+2.4.2.1;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;Reactome: R-HSA-74259;MetaCyc: PWY-6620;MetaCyc: PWY-6608	"Pyrimidine metabolism";"Inosine 5'-phosphate degradation";"Arsenate detoxification I (mammalian)";"Nucleoside and nucleotide degradation (archaea)";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Fluoroacetate and fluorothreonine biosynthesis";"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage III";"Salinosporamide A biosynthesis";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Purine catabolism";"Guanine and guanosine salvage";"Guanosine nucleotides degradation III"
XP_053618629.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053622670.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_053615992.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_053610132.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_053621070.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053607544.1	7	Reactome: R-HSA-165181;Reactome: R-HSA-198323;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-5674400	"Inhibition of TSC complex formation by PKB";"AKT phosphorylates targets in the cytosol";"TBC/RABGAPs";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_053622088.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053602941.1	16	Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-1250196;Reactome: R-HSA-1250342;Reactome: R-HSA-1236394;Reactome: R-HSA-1251985;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795;Reactome: R-HSA-6785631;Reactome: R-HSA-1963642;Reactome: R-HSA-1963640;Reactome: R-HSA-1250347;Reactome: R-HSA-9664565;Reactome: R-HSA-5673001;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"SHC1 events in ERBB2 signaling";"PI3K events in ERBB4 signaling";"Signaling by ERBB4";"Nuclear signaling by ERBB4";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling";"ERBB2 Regulates Cell Motility";"PI3K events in ERBB2 signaling";"GRB2 events in ERBB2 signaling";"SHC1 events in ERBB4 signaling";"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling"
XP_053612190.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053610455.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053613846.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053624688.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053615272.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053607233.1	25	Reactome: R-HSA-9009391;Reactome: R-HSA-163359;Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-381676;Reactome: R-HSA-456926;Reactome: R-HSA-392851;Reactome: R-HSA-392170;Reactome: R-HSA-381771;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-418555;Reactome: R-HSA-4086398;Reactome: R-HSA-418592	"Extra-nuclear estrogen signaling";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 12";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G-protein activation";"G alpha (s) signalling events";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 1"
XP_053602104.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_053618823.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_053612272.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053617135.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053611687.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053613399.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053620366.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053608456.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053599860.1	26	Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-9617629;Reactome: R-HSA-933541;Reactome: R-HSA-210744;Reactome: R-HSA-381340;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-2122947;Reactome: R-HSA-1234158;Reactome: R-HSA-201722;Reactome: R-HSA-9013695;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-3899300;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-3134973;Reactome: R-HSA-2894862;Reactome: R-HSA-8866907;Reactome: R-HSA-918233;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856	"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"Regulation of FOXO transcriptional activity by acetylation";"TRAF6 mediated IRF7 activation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Transcriptional regulation of white adipocyte differentiation";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"Circadian Clock";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression by Hypoxia-inducible Factor";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH4 Intracellular Domain Regulates Transcription";"Attenuation phase";"Estrogen-dependent gene expression";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"TRAF3-dependent IRF activation pathway";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling"
XP_053602131.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_053611014.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053614966.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_053600888.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-3232118;Reactome: R-HSA-5693571	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"SUMOylation of transcription factors";"Nonhomologous End-Joining (NHEJ)"
XP_053620012.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_053609335.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053615576.1	5	KEGG: 00740+2.7.1.26;MetaCyc: PWY-7863;MetaCyc: PWY-6168;MetaCyc: PWY-5523;Reactome: R-HSA-196843	"Riboflavin metabolism";"Roseoflavin biosynthesis";"Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Vitamin B2 (riboflavin) metabolism"
XP_053615640.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_053625426.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053603527.1	14	KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-975634;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4	"Ether lipid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Retinoid metabolism and transport";"Plasmalogen degradation";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism"
XP_053624804.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_053606751.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_053617097.1	12	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Human papillomavirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053613760.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_053600551.1	2	KEGG: 00052+3.2.1.26;KEGG: 00500+3.2.1.26	"Galactose metabolism";"Starch and sucrose metabolism"
XP_053610053.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053612089.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_053621385.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_053617219.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_053614294.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294	"SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors"
XP_053603449.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"HCMV Early Events";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Aggrephagy"
XP_053614755.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_053604169.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI"
XP_053620034.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053620972.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053621465.1	6	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-6798695	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Neutrophil degranulation"
XP_053623161.1	19	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-3000480;Reactome: R-HSA-975634	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"LDL clearance";"LDL remodeling";"Regulation of TLR by endogenous ligand";"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"VLDL assembly";"Chylomicron remodeling";"VLDL clearance";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Scavenging by Class A Receptors";"Retinoid metabolism and transport"
XP_053602828.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041	"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis"
XP_053601575.1	11	Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-164378	"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Hedgehog 'off' state";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling"
XP_053599677.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053618627.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053608667.1	8	Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-69091	"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Polymerase switching"
XP_053602801.1	6	KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-9615017	"Tryptophan metabolism";"Detoxification of Reactive Oxygen Species";"Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_053623398.1	4	Reactome: R-HSA-8950505;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-3371453	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Mitochondrial protein import";"Cristae formation";"Regulation of HSF1-mediated heat shock response"
XP_053625230.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053600604.1	3	Reactome: R-HSA-2672351;Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"Stimuli-sensing channels";"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_053603839.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053614032.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053609881.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_053623568.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_053624465.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053618090.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_053616939.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits"
XP_053620292.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_053607438.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-7559	"Glutathione metabolism";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway"
XP_053603633.1	3	MetaCyc: PWY-5963;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9	"Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_053609249.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053607510.1	6	KEGG: 00020+4.2.1.3;Reactome: R-HSA-1268020;Reactome: R-HSA-71403;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33	"Citrate cycle (TCA cycle)";"Mitochondrial protein import";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis"
XP_053613051.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053608004.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053615552.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053620170.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_053613397.1	4	KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581;MetaCyc: PWY-7887;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis"
XP_053611689.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053611040.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_053614356.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053610114.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_053617620.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_053620163.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_053618533.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053618653.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053610802.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6804756	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation"
XP_053605756.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_053620956.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_053606784.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_053625750.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_053611024.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053625637.1	5	KEGG: 00330+1.14.13.39;Reactome: R-HSA-392154;Reactome: R-HSA-1222556;KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983	"Arginine and proline metabolism";"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)"
XP_053617644.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053625279.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053619131.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053604497.1	8	Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-8953750;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695	"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"Transcriptional Regulation by E2F6";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation"
XP_053607830.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053618220.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053604607.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_053608260.1	9	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway"
XP_053624118.1	7	Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-68949	"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin"
XP_053607440.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053620095.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_053616290.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053602007.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053606369.1	24	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-444257;Reactome: R-HSA-2730905;Reactome: R-HSA-354192;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-165158;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-392451;Reactome: R-HSA-114604;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9634635;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-5218921	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"RSK activation";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"RHO GTPases activate PKNs";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Activation of AKT2";"mTOR signaling pathway";"Regulation of TP53 Degradation";"G beta:gamma signalling through PI3Kgamma";"GPVI-mediated activation cascade";"Human papillomavirus infection";"Estrogen-stimulated signaling through PRKCZ";"Thermogenesis";"PI3K-Akt signaling pathway";"PIP3 activates AKT signaling";"VEGFR2 mediated cell proliferation"
XP_053611896.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053605778.1	2	Reactome: R-HSA-5654726;Reactome: R-HSA-190373	"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation"
XP_053624793.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053607729.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053602895.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_053618436.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
XP_053602778.1	6	Reactome: R-HSA-9022537;Reactome: R-HSA-1989781;Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569	"Loss of MECP2 binding ability to the NCoR/SMRT complex";"PPARA activates gene expression";"HCMV Early Events";"HDACs deacetylate histones";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_053622103.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-430039;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Minor Pathway"
XP_053611038.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053611349.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053618813.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_053601587.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_053599685.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_053615247.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053603863.1	5	KEGG: 00860+2.3.1.37;MetaCyc: PWY-5189;KEGG: 00260+2.3.1.37;MetaCyc: PWY-7536;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Glycine, serine and threonine metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Heme biosynthesis"
XP_053624645.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_053617891.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_053609190.1	12	KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5655302;Reactome: R-HSA-1839117;Reactome: R-HSA-193648;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Rho GTPase cycle";"Relaxin signaling pathway";"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants";"NRAGE signals death through JNK";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_053605822.1	9	MetaCyc: PWY-5744;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1	"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism"
XP_053609394.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_053617988.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053615151.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053607911.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053618619.1	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_053625523.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053623994.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053609992.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053623562.1	4	Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;MetaCyc: PWY-7437	"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation"
XP_053608447.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6787450	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_053604780.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_053608837.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_053613629.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_053615473.1	13	KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-5537;MetaCyc: PWY-6969;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5	"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism"
XP_053608993.1	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_053609925.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_053624661.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053620949.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_053619538.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_053604064.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053624511.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053614024.1	4	Reactome: R-HSA-937039;MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-9020702	"IRAK1 recruits IKK complex";"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling"
XP_053600799.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-6804757;Reactome: R-HSA-9609690	"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation";"HCMV Early Events"
XP_053619410.1	10	MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.15	"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Glycerolipid metabolism"
XP_053601607.1	3	KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
XP_053601916.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_053610977.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053625248.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_053603744.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053625639.1	5	MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39;Reactome: R-HSA-1222556;Reactome: R-HSA-392154;KEGG: 00330+1.14.13.39	"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Arginine and proline metabolism"
XP_053612075.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_053622639.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination"
XP_053599630.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053620583.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_053604609.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_053623491.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053623628.1	10	Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-200425;Reactome: R-HSA-1445148;Reactome: R-HSA-380972	"Activation of AMPK downstream of NMDARs";"Lipophagy";"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Carnitine metabolism";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_053613244.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_053604499.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-6803207;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-8953750;Reactome: R-HSA-111463;Reactome: R-HSA-111464	"Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"Transcriptional Regulation by E2F6";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_053604052.1	6	Reactome: R-HSA-73817;KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234;MetaCyc: PWY-6123;MetaCyc: PWY-6124;KEGG: 00230+3.5.4.10+2.1.2.3	"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism"
XP_053623601.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_053602009.1	17	Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_053605652.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism"
XP_053606367.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053602532.1	7	Reactome: R-HSA-110362;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-2173795;Reactome: R-HSA-5685939;Reactome: R-HSA-5696400	"POLB-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER"
XP_053602652.1	25	Reactome: R-HSA-8936459;Reactome: R-HSA-8878166;Reactome: R-HSA-8931987;Reactome: R-HSA-8934593;Reactome: R-HSA-8951936;Reactome: R-HSA-8951911;Reactome: R-HSA-8939243;Reactome: R-HSA-8935964;Reactome: R-HSA-8941333;Reactome: R-HSA-8939245;Reactome: R-HSA-8877330;Reactome: R-HSA-8941332;Reactome: R-HSA-8939236;Reactome: R-HSA-8941284;Reactome: R-HSA-8939902;Reactome: R-HSA-8940973;Reactome: R-HSA-8939242;Reactome: R-HSA-9018519;Reactome: R-HSA-8941326;Reactome: R-HSA-9616222;Reactome: R-HSA-8939246;Reactome: R-HSA-8939256;Reactome: R-HSA-8949275;Reactome: R-HSA-8939247;Reactome: R-HSA-8941858	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by RUNX2";"RUNX1 regulates estrogen receptor mediated transcription";"Regulation of RUNX1 Expression and Activity";"RUNX3 regulates p14-ARF";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates expression of components of tight junctions";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates chondrocyte maturation";"Regulation of RUNX2 expression and activity";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"Estrogen-dependent gene expression";"RUNX2 regulates bone development";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in interleukin signaling";"Regulation of RUNX3 expression and activity"
XP_053600360.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_053610320.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053613533.1	11	MetaCyc: PWY-6383;Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-6174;MetaCyc: PWY-6859;MetaCyc: PWY-7524;MetaCyc: PWY-7391;MetaCyc: PWY-7102;MetaCyc: PWY-7560;MetaCyc: PWY-5123;KEGG: 00900+5.3.3.2	"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"All-trans-farnesol biosynthesis";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Bisabolene biosynthesis (engineered)";"Methylerythritol phosphate pathway II";"Trans, trans-farnesyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis"
XP_053624502.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053620215.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_053606487.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053607727.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053610017.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053601589.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557	"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis"
XP_053615249.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_053607885.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053611347.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_053610138.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_053608478.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_053615881.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053608553.1	9	KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-6367;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-112043	"Phosphatidylinositol signaling system";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events"
XP_053618051.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053601076.1	5	Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604	"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling"
XP_053611119.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053625082.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_053602676.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053602818.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)"
XP_053622082.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053599642.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053618617.1	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_053618773.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_053623581.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_053619355.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053616886.1	4	Reactome: R-HSA-69205;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962	"G1/S-Specific Transcription";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_053618084.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053612278.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053617390.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_053612854.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053615278.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-5617472;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA"
XP_053616731.1	7	KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661	"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation"
XP_053624682.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053604076.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053613627.1	4	Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation"
XP_053602747.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053625997.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_053624379.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_053600797.1	6	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures"
XP_053626130.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053606790.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9	"Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis"
XP_053603371.1	5	Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-5617472	"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_053600590.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053622997.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053603517.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_053601609.1	3	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation"
XP_053625443.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053610979.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053613859.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053613187.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053624122.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_053619444.1	9	MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52	"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation"
XP_053611675.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053612335.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053624227.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_053600577.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;Reactome: R-HSA-2206291	"HS-GAG degradation";"Neutrophil degranulation";"MPS IIIC - Sanfilippo syndrome C"
XP_053600770.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_053615402.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053614025.1	4	Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-975144	"Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_053601041.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053603403.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400	"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Dual Incision in GG-NER"
XP_053621988.1	17	MetaCyc: PWY-5789;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;Reactome: R-HSA-163765;MetaCyc: PWY-6679;KEGG: 00061+6.4.1.2;KEGG: 00720+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-4381;Reactome: R-HSA-200425;MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"ChREBP activates metabolic gene expression";"Jadomycin biosynthesis";"Fatty acid biosynthesis";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)"
XP_053602283.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_053606613.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination"
XP_053616248.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_053609938.1	4	Reactome: R-HSA-964975;MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5	"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism"
XP_053618030.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053606646.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053617206.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_053603745.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053622156.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053623707.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053607181.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_053619525.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053609148.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434	"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053620387.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_053612185.1	12	Reactome: R-HSA-451308;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001;Reactome: R-HSA-447038;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-9617324	"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade";"NrCAM interactions";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_053610723.1	3	KEGG: 00790+1.1.1.153;Reactome: R-HSA-1474151;Reactome: R-HSA-203615	"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation"
XP_053611201.1	4	KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817	"Purine metabolism";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis"
XP_053615914.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053610642.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053614987.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053613337.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513	"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_053609924.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_053603313.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_053604626.1	6	KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-7165;KEGG: 00053+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221	"Caprolactam degradation";"Sorbitol biosynthesis II";"L-ascorbate biosynthesis VI (engineered pathway)";"Ascorbate and aldarate metabolism";"Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_053609541.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053619362.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_053619043.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_053606393.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053602894.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615	"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation"
XP_053615312.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053599684.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_053614201.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_053604268.1	3	KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_053624644.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_053614228.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053619016.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053609395.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_053606205.1	3	KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367;MetaCyc: PWY-6368	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation"
XP_053603899.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-422085	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_053611025.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053608202.1	16	Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579	"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"HATs acetylate histones";"Estrogen-dependent gene expression";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange"
XP_053624891.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_053617645.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053624988.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615	"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation"
XP_053599948.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_053620094.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_053617793.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_053605641.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_053624769.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_053622172.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053610550.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination"
XP_053610630.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_053611092.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_053609203.1	8	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-5689880;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_053600904.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053613261.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits"
XP_053624229.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_053599977.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-194840	"RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle"
XP_053599808.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_053608967.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053601383.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053617682.1	31	MetaCyc: PWY-4381;MetaCyc: PWY-7663;MetaCyc: PWY-6799;Reactome: R-HSA-199220;MetaCyc: PWY-5989;MetaCyc: PWY-5966-1;Reactome: R-HSA-75105;MetaCyc: PWY-5973;MetaCyc: PWY-8047;MetaCyc: PWYG-321;MetaCyc: PWY-5366;Reactome: R-HSA-163765;MetaCyc: PWY-5994;MetaCyc: PWY-7746;MetaCyc: PWY-8012;MetaCyc: PWY-5367;MetaCyc: PWY-5147;MetaCyc: PWY-7858;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-5971;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168;MetaCyc: PWY-7664;MetaCyc: PWY-6113;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7723;MetaCyc: PWY-6519;MetaCyc: PWY-8049;MetaCyc: PWY-5142;MetaCyc: PWY-7388	"Fatty acid biosynthesis initiation (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Vitamin B5 (pantothenate) metabolism";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"Cis-vaccenate biosynthesis";"Bryostatin biosynthesis";"";"Palmitoleate biosynthesis II (plants and bacteria)";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"Mupirocin biosynthesis";"Petroselinate biosynthesis";"Oleate biosynthesis I (plants)";"(5Z)-dodecenoate biosynthesis II";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis IV (anaerobic)";"Superpathway of mycolate biosynthesis";"Biotin metabolism";"Bacterial bioluminescence";"8-amino-7-oxononanoate biosynthesis I";"Pederin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)"
XP_053601856.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053612130.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_053600141.1	5	KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;MetaCyc: PWY-7979	"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)"
XP_053613606.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_053618702.1	4	Reactome: R-HSA-186763;Reactome: R-HSA-8875555;Reactome: R-HSA-912631;Reactome: R-HSA-8875656	"Downstream signal transduction";"MET activates RAP1 and RAC1";"Regulation of signaling by CBL";"MET receptor recycling"
XP_053620672.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_053621560.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_053608359.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053608211.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053612334.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053611674.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053617122.1	7	KEGG: 00564+2.7.8.11;MetaCyc: PWY-7625;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6352;Reactome: R-HSA-1483226;MetaCyc: PWY-6351;KEGG: 00562+2.7.8.11	"Glycerophospholipid metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Synthesis of PI";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism"
XP_053621573.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-6804756	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation"
XP_053619354.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053602191.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053614212.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_053618085.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053617379.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_053604872.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_053617195.1	19	MetaCyc: PWY-7115;KEGG: 00710+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-561;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00680+1.1.1.37;KEGG: 00270+1.1.1.37;Reactome: R-HSA-71403;MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-1622	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Methane metabolism";"Cysteine and methionine metabolism";"Citric acid cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Formaldehyde assimilation I (serine pathway)"
XP_053620214.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1"
XP_053619381.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053611768.1	34	Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-167152;Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-69273;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-8939236;Reactome: R-HSA-73863;Reactome: R-HSA-69231;Reactome: R-HSA-167200;Reactome: R-HSA-69202;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-69656;Reactome: R-HSA-6796648;Reactome: R-HSA-72086	"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV elongation complex in the absence of HIV Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Cyclin A/B1/B2 associated events during G2/M transition";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Transcription Termination";"Cyclin D associated events in G1";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"Cyclin A:Cdk2-associated events at S phase entry";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping"
XP_053620536.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_053601728.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053603116.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_053617502.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053607884.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_053610685.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_053609177.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins"
XP_053622010.1	3	KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117;MetaCyc: PWY-0	"Arginine and proline metabolism";"Spermine and spermidine degradation I";"Putrescine degradation III"
XP_053611989.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053612142.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053618166.1	10	MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-7328;MetaCyc: PWY-7344	"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"UDP-alpha-D-galactose biosynthesis"
XP_053621229.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_053625327.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_053600810.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053621390.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053603897.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557	"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis"
XP_053613245.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_053621194.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053607706.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_053604470.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053607415.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053623047.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053626075.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_053624560.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053603782.1	4	MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;Reactome: R-HSA-71737	"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III";"Pyrophosphate hydrolysis"
XP_053624767.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_053610125.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053612783.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_053615783.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_053612411.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_053615203.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_053617134.1	5	KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis"
XP_053610591.1	8	Reactome: R-HSA-9636467;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-77387;Reactome: R-HSA-167590;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Blockage of phagosome acidification";"Transferrin endocytosis and recycling";"Ion channel transport";"Nef Mediated CD8 Down-regulation";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_053622147.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053612203.1	13	Reactome: R-HSA-2160916;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902	"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"CS/DS degradation";"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)"
XP_053613483.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053622319.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053606829.1	3	Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B	"Neutrophil degranulation";"Folate biosynthesis";"Glutamate removal from folates"
XP_053611015.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053624850.1	6	Reactome: R-HSA-9033241;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6	"Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism"
XP_053608761.1	3	Reactome: R-HSA-6787450;MetaCyc: PWY-7892;MetaCyc: PWY-7887	"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation"
XP_053599771.1	8	MetaCyc: PWY-1861;Reactome: R-HSA-8950505;Reactome: R-HSA-163754;KEGG: 00030+2.2.1.2;Reactome: R-HSA-6791055;Reactome: R-HSA-6791462;MetaCyc: PWY-5723;Reactome: R-HSA-71336	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Rubisco shunt";"Pentose phosphate pathway"
XP_053614218.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053619026.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053607545.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-165181;Reactome: R-HSA-198323;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"Inhibition of TSC complex formation by PKB";"AKT phosphorylates targets in the cytosol";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_053617101.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053624135.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation"
XP_053613363.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_053623314.1	7	KEGG: 00310+2.3.1.61;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71403;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+2.3.1.61;Reactome: R-HSA-71064	"Lysine degradation";"Tryptophan metabolism";"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine catabolism"
XP_053604616.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_053603323.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_053601439.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053620197.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053600650.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053612322.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_053608346.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053606537.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053625937.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
YP_009166947.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053615322.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053615541.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_053620764.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_053610713.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053607023.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_053617342.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053607561.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_053624099.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053605964.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053610239.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053605592.1	7	KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_053618337.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053601907.1	7	Reactome: R-HSA-445095;Reactome: R-HSA-264870;Reactome: R-HSA-6807878;Reactome: R-HSA-373753;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6798695	"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins";"COPI-mediated anterograde transport";"Nephrin family interactions";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Neutrophil degranulation"
XP_053599690.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_053602880.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670	"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation";"Hedgehog 'off' state";"Purine metabolism";"Adenylate cyclase inhibitory pathway"
XP_053606474.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053608403.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_053603969.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs"
XP_053609625.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053608693.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053615938.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_053612796.1	11	MetaCyc: PWY-5695;MetaCyc: PWY-6596;MetaCyc: PWY-6999;MetaCyc: PWY-6606;Reactome: R-HSA-8851680;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6608;MetaCyc: PWY-6607;MetaCyc: PWY-6538;MetaCyc: PWY-5497;Reactome: R-HSA-74259	"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I";"Theophylline degradation";"Guanosine nucleotides degradation II";"Butyrophilin (BTN) family interactions";"Purine metabolism";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation I";"Caffeine degradation III (bacteria, via demethylation)";"Purine nucleobases degradation II (anaerobic)";"Purine catabolism"
XP_053601566.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053616285.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053615615.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053615796.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053600308.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_053621850.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053608745.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053619283.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_053609402.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053609692.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-73856	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination"
XP_053616242.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_053607492.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053607602.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053612421.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053602461.1	5	MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817	"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_053613288.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_053615698.1	3	Reactome: R-HSA-8936459;Reactome: R-HSA-383280;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines"
XP_053610115.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_053612408.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_053600820.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_053614098.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053608782.1	9	MetaCyc: PWY-8086;MetaCyc: PWY-6142;Reactome: R-HSA-3371599;KEGG: 00020+6.4.1.1;Reactome: R-HSA-70263;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6146;KEGG: 00620+6.4.1.1	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Defective HLCS causes multiple carboxylase deficiency";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Pyruvate metabolism"
XP_053621733.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053609932.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053606785.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_053602296.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053609142.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_053612177.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_053617385.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053614413.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_053599930.1	6	Reactome: R-HSA-110357;Reactome: R-HSA-5651801;Reactome: R-HSA-110373;Reactome: R-HSA-110362;Reactome: R-HSA-73933;Reactome: R-HSA-73930	"Displacement of DNA glycosylase by APEX1";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"
XP_053620375.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-380994	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_053620224.1	18	Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-77075	"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_053625939.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_053600739.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_053619598.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-381038	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes"
XP_053601262.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053620199.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053608143.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_053614295.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118	"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors"
XP_053615318.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_053610237.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053611781.1	2	Reactome: R-HSA-442982;Reactome: R-HSA-5673001	"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade"
XP_053621464.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053619368.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_053609855.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053609328.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_053602354.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053601574.1	11	Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-164378	"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Hedgehog 'off' state";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"PKA activation in glucagon signalling"
XP_053609940.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053601909.1	7	Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-375165;Reactome: R-HSA-5673001	"Nephrin family interactions";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade"
XP_053606386.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163615	"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Hedgehog 'off' state";"PKA activation"
XP_053604718.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_053618339.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-9010553	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs"
XP_053600605.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053603506.1	3	Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-4419969	"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina"
XP_053623332.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053613927.1	12	Reactome: R-HSA-749476;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-73762;Reactome: R-HSA-76066;Reactome: R-HSA-73863;Reactome: R-HSA-1834949;Reactome: R-HSA-427413;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_053603967.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053609130.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_053608221.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053621180.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053610382.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053624805.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_053603211.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053620776.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053599811.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-2022854;Reactome: R-HSA-5083627	"O-linked glycosylation";"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_053621384.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_053619488.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053614324.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053603440.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257	"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Resolution of Sister Chromatid Cohesion"
XP_053623666.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053613253.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_053609758.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053602252.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_053605252.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053604160.1	4	MetaCyc: PWY-5912;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581	"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"Methylation"
XP_053622481.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053619171.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_053620924.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_053607870.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053600913.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_053601594.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053623228.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053613644.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_053622677.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_053601962.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053621337.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_053625239.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053622361.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053616942.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053621282.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053614049.1	6	MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7290	"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_053612649.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_053611078.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_053608544.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_053606271.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_053620938.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053618850.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-111447	"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria"
XP_053623516.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053602996.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_053620615.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053612080.1	30	Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-5696400;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-6781823;Reactome: R-HSA-2564830;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-6796648	"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of TC-NER Pre-Incision Complex";"Cytosolic iron-sulfur cluster assembly";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes"
XP_053609232.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053620796.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_053624282.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_053619866.1	5	MetaCyc: PWY-7761;MetaCyc: PWY-5381;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653	"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_053611680.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053623025.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053610319.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053610251.1	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
XP_053615433.1	3	KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041;Reactome: R-HSA-174403	"Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione synthesis and recycling"
XP_053615678.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053615816.1	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
XP_053618961.1	26	Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-389960	"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HCMV Early Events";"Mitotic Prometaphase";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Kinesins";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Formation of tubulin folding intermediates by CCT/TriC"
XP_053612678.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_053599867.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053611049.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_053611338.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_053620203.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053614078.1	22	Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-2500257	"Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"RAF activation";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion"
XP_053616140.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053616344.1	27	Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-4551638	"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins"
XP_053605276.1	5	Reactome: R-HSA-532668;Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-901042	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle"
XP_053615843.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053611324.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053617857.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_053601364.1	14	Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-174411	"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere"
XP_053621077.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053614707.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588	"HCMV Late Events";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_053616455.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053618099.1	2	Reactome: R-HSA-389397;Reactome: R-HSA-416476	"Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events"
XP_053610937.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053618452.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053612197.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_053607744.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_053609240.1	6	KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433;MetaCyc: PWY-7290;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709	"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins"
XP_053616029.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053605307.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053620395.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053619578.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053625454.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_053618464.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_053608424.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053624079.1	19	KEGG: 00983+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7176;MetaCyc: PWY-7226;Reactome: R-HSA-380320;MetaCyc: PWY-7222;Reactome: R-HSA-380270;KEGG: 00230+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-7227;MetaCyc: PWY-7197;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7224	"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Recruitment of NuMA to mitotic centrosomes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of mitotic centrosome proteins and complexes";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage"
XP_053617653.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053617533.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7601	"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_053610407.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_053601352.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053608660.1	2	Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Formation of apoptosome";"Regulation of the apoptosome activity"
XP_053622462.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053599670.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053625462.1	3	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation"
XP_053624586.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053606494.1	13	KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916	"Other glycan degradation";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"CS/DS degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation"
XP_053606604.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_053621339.1	3	KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041;Reactome: R-HSA-174403	"Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione synthesis and recycling"
XP_053615776.1	4	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_053608510.1	2	Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1	"Vitamin B1 (thiamin) metabolism";"Purine metabolism"
XP_053610178.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_053608717.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_053612776.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_053603520.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053625951.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053613767.1	57	Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-68827;Reactome: R-HSA-532668;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346	"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Separation of Sister Chromatids";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"CDT1 association with the CDC6:ORC:origin complex";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Neddylation";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis"
XP_053622951.1	5	MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919;Reactome: R-HSA-4793954;Reactome: R-HSA-532668	"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_053609469.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053618384.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053609672.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053604376.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_053623674.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053610317.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053616771.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-381183	"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_053599869.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053622006.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053612238.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053603304.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842	"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione metabolism";"Glutathione-mediated detoxification II"
XP_053625984.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053620408.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_053605636.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_053601376.1	4	Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-72086	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping"
XP_053603100.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_053620698.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_053618351.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053622984.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_053602264.1	3	MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_053617859.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053621079.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053615375.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053611555.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_053604352.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053615199.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_053610020.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053601954.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053604898.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053607517.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053607371.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_053624339.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_053615752.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_053612752.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958	"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_053619258.1	8	KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1	"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Glycolysis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis"
XP_053601358.1	3	MetaCyc: PWY-0;MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57	"Putrescine degradation III";"Spermine and spermidine degradation I";"Arginine and proline metabolism"
XP_053611865.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053613099.1	3	KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685	"Glutathione metabolism";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species"
XP_053600489.1	5	Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;Reactome: R-HSA-165159	"HSF1-dependent transactivation";"mTORC1-mediated signalling";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling"
XP_053624593.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053620066.1	3	MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531	"Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus"
XP_053601892.1	4	KEGG: 00510+2.4.1.259+2.4.1.261;KEGG: 00513+2.4.1.261;Reactome: R-HSA-446193;Reactome: R-HSA-4720454	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG9 causes ALG9-CDG (CDG-1l)"
XP_053614289.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_053622468.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_053621370.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053623106.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-381038;Reactome: R-HSA-2565942	"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"XBP1(S) activates chaperone genes";"Regulation of PLK1 Activity at G2/M Transition"
XP_053625550.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053606950.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_053610172.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053606435.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_053612094.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389	"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_053625630.1	2	Reactome: R-HSA-168138;Reactome: R-HSA-983231	"Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production"
XP_053607837.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053604600.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053599639.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053608267.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053624030.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053606845.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-975957	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053619996.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation"
XP_053600599.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_053624483.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053612232.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053618988.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_053618891.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_053601600.1	3	MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51	"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Other glycan degradation"
XP_053608155.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053613476.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053620692.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_053613850.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053611694.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053618769.1	13	Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-114508;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-381676;Reactome: R-HSA-2871809	"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Effects of PIP2 hydrolysis";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization"
XP_053625723.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_053604825.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053614865.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053625642.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053609764.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053622642.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_053619252.1	56	Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"UCH proteinases";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Degradation of DVL";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation"
XP_053613135.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_053607260.1	2	Reactome: R-HSA-5633231;Reactome: R-HSA-446193	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_053614314.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_053614110.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_053618644.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053617175.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053615387.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053606373.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053605258.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_053611144.1	20	KEGG: 00410+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-7291;Reactome: R-HSA-9033241;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-6920	"beta-Alanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"Propanoate metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)"
XP_053622685.1	6	MetaCyc: PWY-7920;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952	"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_053602258.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_053614056.1	5	Reactome: R-HSA-5610785;Reactome: R-HSA-5610787;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684	"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'off' state";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state"
XP_053611340.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_053601789.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226	"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053608331.1	14	MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7417;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51	"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism"
XP_053611901.1	4	Reactome: R-HSA-4755583;MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108;Reactome: R-HSA-446199	"Defective DOLK causes DOLK-CDG (CDG-1m)";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_053616684.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053619264.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053609375.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation"
XP_053623303.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053622270.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_053600959.1	14	KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-7589;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7417;Reactome: R-HSA-1483166	"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA"
XP_053620411.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053601655.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053625125.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade"
XP_053616948.1	12	KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00680+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1042;MetaCyc: PWY-5484;Reactome: R-HSA-70263;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13	"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis";"Fructose and mannose metabolism"
XP_053608269.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation"
XP_053618229.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_053607839.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053608100.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053609238.1	6	MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290	"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_053606360.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053616299.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)"
XP_053613805.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_053610327.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053607449.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053611072.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053624702.1	10	Reactome: R-HSA-70263;KEGG: 00710+5.3.1.1;MetaCyc: PWY-7003;MetaCyc: PWY-5484;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70171;MetaCyc: PWY-6142;KEGG: 00051+5.3.1.1;KEGG: 00562+5.3.1.1;MetaCyc: PWY-1042	"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Fructose and mannose metabolism";"Inositol phosphate metabolism";"Glycolysis IV (plant cytosol)"
XP_053611934.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053613733.1	4	Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277	"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex"
XP_053616124.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6807505	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes"
XP_053611332.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_053619419.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_053612672.1	14	Reactome: R-HSA-8986944;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Regulation of MECP2 expression and activity"
XP_053621927.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_053603438.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053606590.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Protein ubiquitination";"Fanconi Anemia Pathway"
XP_053622990.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_053603510.1	3	Reactome: R-HSA-6783310;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Fanconi Anemia Pathway";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053617051.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_053607553.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053606797.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053620130.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053607633.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_053607478.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053599999.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053612469.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_053616504.1	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_053609776.1	10	Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;MetaCyc: PWY-6807;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23	"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)";"HS-GAG degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Other glycan degradation"
XP_053602055.1	7	MetaCyc: PWY-6277;KEGG: 00250+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6122;Reactome: R-HSA-73817	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Alanine, aspartate and glutamate metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis"
XP_053618767.1	14	MetaCyc: PWY-8055;Reactome: R-HSA-1483191;KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00600+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8052;MetaCyc: PWY-8053;MetaCyc: PWY-7782;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8051;Reactome: R-HSA-1483213;KEGG: 00565+3.1.3.4	"Palmitoyl ethanolamide biosynthesis";"Synthesis of PC";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Sphingolipid metabolism";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Synthesis of PE";"Ether lipid metabolism"
XP_053613384.1	6	MetaCyc: PWY-2941;MetaCyc: PWY-2942;KEGG: 00261+4.3.3.7;MetaCyc: PWY-5097;MetaCyc: PWY-8088;KEGG: 00300+4.3.3.7	"L-lysine biosynthesis II";"L-lysine biosynthesis III";"Monobactam biosynthesis";"L-lysine biosynthesis VI";"Dipicolinate biosynthesis";"Lysine biosynthesis"
XP_053609903.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053624953.1	13	Reactome: R-HSA-9027277;MetaCyc: PWY-8052;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;MetaCyc: PWY-7039;Reactome: R-HSA-202433;Reactome: R-HSA-2424491;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2871796	"Erythropoietin activates Phospholipase C gamma (PLCG)";"2-arachidonoylglycerol biosynthesis";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"Phosphatidate metabolism, as a signaling molecule";"Generation of second messenger molecules";"DAP12 signaling";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"FCERI mediated MAPK activation"
XP_053614144.1	13	MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101	"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"CS/DS degradation"
XP_053618610.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053620301.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053614340.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_053604789.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053607107.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053611056.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053608414.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation"
XP_053604968.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14	"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis"
XP_053624166.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053621085.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053615389.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053603660.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_053613620.1	8	Reactome: R-HSA-9633012;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_053599731.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_053602715.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis"
XP_053620184.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_053604824.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053603286.1	9	KEGG: 00564+1.1.1.8;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981;MetaCyc: PWY-6118;MetaCyc: PWY-7385;MetaCyc: PWY-7411	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)"
XP_053614864.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_053605696.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053623700.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053602406.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053620380.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053624846.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_053606763.1	9	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-191859;Reactome: R-HSA-381340	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"snRNP Assembly";"Transcriptional regulation of white adipocyte differentiation"
XP_053610061.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-9639288	"Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1"
XP_053617370.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053617483.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053614315.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_053603057.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053617174.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053604096.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053607202.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_053601662.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_053625821.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053603391.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-399997	"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion"
XP_053600777.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_053624399.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053606311.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_053606577.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053610248.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053623153.1	11	Reactome: R-HSA-3270619;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"IRF3-mediated induction of type I IFN";"Human cytomegalovirus infection";"mTOR signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_053604838.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_053608154.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053609596.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_053612139.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_053611716.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis"
XP_053611695.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053608350.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053611405.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053622297.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_053612095.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-73762	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation"
XP_053621220.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_053601838.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053614743.1	7	Reactome: R-HSA-171306;Reactome: R-HSA-110331;Reactome: R-HSA-2559586;Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110330	"Packaging Of Telomere Ends";"Cleavage of the damaged purine";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_053608013.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_053618511.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053602316.1	5	MetaCyc: PWY-6277;MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6122;Reactome: R-HSA-73817	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis"
XP_053609012.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_053601448.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_053603023.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053610637.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition"
XP_053613508.1	7	Reactome: R-HSA-5628897;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2	"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism"
XP_053605062.1	8	KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171	"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Glycolysis"
XP_053605343.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053614405.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_053606844.1	2	Reactome: R-HSA-442660;Reactome: R-HSA-352230	"Na+/Cl- dependent neurotransmitter transporters";"Amino acid transport across the plasma membrane"
XP_053616388.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053602062.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_053613070.1	5	MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621	"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine catabolism"
XP_053607357.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_053621813.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_053611864.1	2	Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053614182.1	7	Reactome: R-HSA-3000178;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629	"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
XP_053623127.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053608608.1	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_053610045.1	16	Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-416993;Reactome: R-HSA-2132295;Reactome: R-HSA-164939;Reactome: R-HSA-437239;Reactome: R-HSA-167590;Reactome: R-HSA-5099900;Reactome: R-HSA-182218;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-177504;Reactome: R-HSA-8866427;Reactome: R-HSA-196025	"LDL clearance";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Trafficking of GluR2-containing AMPA receptors";"MHC class II antigen presentation";"Nef mediated downregulation of CD28 cell surface expression";"Recycling pathway of L1";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD8 Down-regulation";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"VLDLR internalisation and degradation";"Formation of annular gap junctions"
XP_053610103.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_053604501.1	8	Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-8953750;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-6798695;Reactome: R-HSA-6803207	"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"Transcriptional Regulation by E2F6";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_053604528.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_053620278.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_053625531.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053612947.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_053603059.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053619241.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_053608415.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053608706.1	56	Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-68949	"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Neddylation";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin"
XP_053599963.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_053621084.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053612603.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053615493.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_053615603.1	2	Reactome: R-HSA-8983711;Reactome: R-HSA-909733	"OAS antiviral response";"Interferon alpha/beta signaling"
XP_053617166.1	6	Reactome: R-HSA-139915;Reactome: R-HSA-6803211;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204	"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_053600779.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_053625504.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_053601477.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_053620335.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053623356.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053619503.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_053609001.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_053616505.1	3	KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_053612137.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053610416.1	5	Reactome: R-HSA-1834941;Reactome: R-HSA-3134975;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-3249367	"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"STAT6-mediated induction of chemokines"
XP_053602054.1	7	MetaCyc: PWY-6277;MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6122	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_053616990.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_053622320.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73863	"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_053619123.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053622299.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053625124.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-166166	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade"
XP_053622124.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_053607506.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053610639.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_053603582.1	13	Reactome: R-HSA-3000157;Reactome: R-HSA-186797;Reactome: R-HSA-1442490;Reactome: R-HSA-3000178;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-419037;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-216083;Reactome: R-HSA-1474244	"Laminin interactions";"Signaling by PDGF";"Collagen degradation";"ECM proteoglycans";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"NCAM1 interactions";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Integrin cell surface interactions";"Extracellular matrix organization"
XP_053613804.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_053622948.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_053601243.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053616125.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-6807505;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes";"Protein ubiquitination"
YP_009166938.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_053625948.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_053611935.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053623294.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053602875.1	11	Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-164378	"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Hedgehog 'off' state";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling"
XP_053609292.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_053600196.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_053622684.1	6	MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143	"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis"
XP_053605798.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7	"Sesamin biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis"
XP_053624773.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_053614161.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_053604121.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053617871.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_053612809.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_053616685.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053609225.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053613831.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053601102.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_053611858.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053611325.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053616454.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053618070.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053623038.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053613206.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_053609807.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053609978.1	29	Reactome: R-HSA-110320;Reactome: R-HSA-912446;Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-5358606;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-5358565;Reactome: R-HSA-5696395;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-69166;Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-3371453;Reactome: R-HSA-5656121;Reactome: R-HSA-3371511;Reactome: R-HSA-5693607;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-6783310;Reactome: R-HSA-176187;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-5693616;Reactome: R-HSA-110314	"Translesion Synthesis by POLH";"Meiotic recombination";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Dual Incision in GG-NER";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Formation of Incision Complex in GG-NER";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by POLI";"HSF1 activation";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Fanconi Anemia Pathway";"Activation of ATR in response to replication stress";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recognition of DNA damage by PCNA-containing replication complex"
XP_053601814.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_053606418.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_053620190.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053600657.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053610088.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-7204;KEGG: 00750+2.7.1.35;Reactome: R-HSA-964975;MetaCyc: PWY-7282	"Neutrophil degranulation";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_053607403.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053625455.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_053625930.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053603621.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053603498.1	5	MetaCyc: PWY-7177;Reactome: R-HSA-499943;MetaCyc: PWY-7185;MetaCyc: PWY-7176;KEGG: 00240+6.3.4.2	"UTP and CTP dephosphorylation II";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism"
YP_009166940.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_053606093.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-72187	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"mRNA 3'-end processing"
XP_053625140.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053613377.1	3	KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693	"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism"
XP_053622140.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053603013.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_053615366.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053623896.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053599571.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_053618342.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway"
XP_053612366.1	6	Reactome: R-HSA-5654712;Reactome: R-HSA-5673001;Reactome: R-HSA-5654706;Reactome: R-HSA-5654693;Reactome: R-HSA-5654700;Reactome: R-HSA-9028731	"FRS-mediated FGFR4 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR2 signaling";"Activated NTRK2 signals through FRS2 and FRS3"
XP_053608023.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053618521.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053620087.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_053608391.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_053612596.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_053617077.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053625942.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_053600742.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053618101.1	2	Reactome: R-HSA-389397;Reactome: R-HSA-416476	"Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events"
XP_053621189.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053608545.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053606308.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_053610663.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_053611994.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053613793.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_053600011.1	8	MetaCyc: PWY-7922;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109	"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis"
XP_053604102.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053605792.1	15	Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-3769402;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-5689896;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-111465;Reactome: R-HSA-5467333;Reactome: R-HSA-195253	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"APC truncation mutants are not K63 polyubiquitinated";"Degradation of beta-catenin by the destruction complex"
XP_053611562.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_053625132.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_053602792.1	26	Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-2132295	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Kinesins";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation"
XP_053618330.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_053620925.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_053624823.1	12	Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-450408;Reactome: R-HSA-9010553	"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"Translation initiation complex formation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs"
XP_053613645.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-6784531	"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus"
XP_053600183.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_053599697.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_053602159.1	4	MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621	"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Pyrimidine catabolism"
XP_053608057.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_053621629.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_053615374.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_053621090.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053611634.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053617496.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_053611554.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053601840.1	14	Reactome: R-HSA-977225;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-6798695;Reactome: R-HSA-193692;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-1474228;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862	"Amyloid fiber formation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"Regulated proteolysis of p75NTR";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Degradation of the extracellular matrix";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_053623347.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053604083.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053612170.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053609215.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053620632.1	11	Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-2173796;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-72163	"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"mRNA Splicing - Major Pathway"
XP_053601955.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053607221.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053602683.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_053618831.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
XP_053619875.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_053612292.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053606739.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053600659.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053613379.1	3	KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693	"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism"
XP_053610242.1	5	Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5620922;Reactome: R-HSA-5610787;Reactome: R-HSA-5632684	"Class B/2 (Secretin family receptors)";"Activation of SMO";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'off' state";"Hedgehog 'on' state"
XP_053625802.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_053616984.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053601668.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053611491.1	12	Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-5362798;Reactome: R-HSA-193692;Reactome: R-HSA-982772;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-75893	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Release of Hh-Np from the secreting cell";"Regulated proteolysis of p75NTR";"Growth hormone receptor signaling";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"TNF signaling"
XP_053611628.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_053603305.1	10	MetaCyc: PWY-8001;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism"
XP_053625771.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_053603162.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053616860.1	3	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.267;Reactome: R-HSA-4724289	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG6 causes ALG6-CDG (CDG-1c)"
XP_053619113.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053600785.1	11	KEGG: 00480+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-7268;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6549;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-7124;MetaCyc: PWY-5913	"Glutathione metabolism";"Citric acid cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"L-glutamine biosynthesis III";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Ethylene biosynthesis V (engineered)";"Partial TCA cycle (obligate autotrophs)"
XP_053622114.1	3	KEGG: 00600+1.14.19.17;Reactome: R-HSA-1660661;MetaCyc: PWY-5129	"Sphingolipid metabolism";"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)"
XP_053611266.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053625985.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053622985.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_053615163.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053621653.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053610426.1	6	Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;MetaCyc: PWY-7900;MetaCyc: PWY-622;Reactome: R-HSA-3878781	"Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Glycogen storage disease type IV (GBE1)"
XP_053616951.1	12	KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-7385;KEGG: 00680+4.1.2.13	"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Fructose and mannose metabolism";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism"
XP_053624244.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_053614628.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053620089.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_053619054.1	6	Reactome: R-HSA-6787450;MetaCyc: PWY-6829;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;MetaCyc: PWY-7286;MetaCyc: PWY-7285	"tRNA modification in the mitochondrion";"Trna methylation (yeast)";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis"
XP_053621187.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053602068.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_053602503.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6781827	"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_053607116.1	16	Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Regulation of PTEN mRNA translation"
XP_053618385.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_053623675.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053614266.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_053603884.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_053604226.1	6	KEGG: 00730+2.7.6.2;Reactome: R-HSA-196819;MetaCyc: PWY-7356;MetaCyc: PWY-6908;MetaCyc: PWY-6907;MetaCyc: PWY-6898	"Thiamine metabolism";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III"
XP_053616462.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_053614634.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_053624090.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053618465.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_053611581.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053605241.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_053616679.1	7	Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-6783310;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-6804756	"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation"
XP_053604518.1	24	Reactome: R-HSA-5610785;Reactome: R-HSA-442720;Reactome: R-HSA-422356;Reactome: R-HSA-5610783;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-163358;Reactome: R-HSA-9010642;Reactome: R-HSA-164378;Reactome: R-HSA-9634600;Reactome: R-HSA-432040;Reactome: R-HSA-4420097;Reactome: R-HSA-8963896;Reactome: R-HSA-5610780;Reactome: R-HSA-163615;Reactome: R-HSA-163560;Reactome: R-HSA-392517;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;KEGG: 04150+2.7.11.11;Reactome: R-HSA-111931;Reactome: R-HSA-5621575;Reactome: R-HSA-5687128;Reactome: R-HSA-8853659	"GLI3 is processed to GLI3R by the proteasome";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Regulation of insulin secretion";"Degradation of GLI2 by the proteasome";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA-mediated phosphorylation of key metabolic factors";"ROBO receptors bind AKAP5";"PKA activation in glucagon signalling";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"VEGFA-VEGFR2 Pathway";"HDL assembly";"Degradation of GLI1 by the proteasome";"PKA activation";"Triglyceride catabolism";"Rap1 signalling";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"mTOR signaling pathway";"PKA-mediated phosphorylation of CREB";"CD209 (DC-SIGN) signaling";"MAPK6/MAPK4 signaling";"RET signaling"
XP_053601774.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053604955.1	5	MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237	"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2"
XP_053603706.1	8	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-6798695;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Neutrophil degranulation";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_053606495.1	13	Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883	"Glycosphingolipid metabolism";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Other glycan degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II"
XP_053612972.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053601111.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-3214858;Reactome: R-HSA-6804760	"snRNP Assembly";"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation"
XP_053625400.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_053615419.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053608180.1	8	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712;MetaCyc: PWY-7980;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Oxidative phosphorylation";"Ion channel transport";"ATP biosynthesis";"Transferrin endocytosis and recycling";"Photosynthesis"
XP_053608384.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053618848.1	6	Reactome: R-HSA-2046106;Reactome: R-HSA-390247;Reactome: R-HSA-5684045;Reactome: R-HSA-9603798;Reactome: R-HSA-1369062;Reactome: R-HSA-2046105	"alpha-linolenic acid (ALA) metabolism";"Beta-oxidation of very long chain fatty acids";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis";"Linoleic acid (LA) metabolism"
XP_053607090.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053616551.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053606053.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053603560.1	13	Reactome: R-HSA-216083;Reactome: R-HSA-2022090;Reactome: R-HSA-1474244;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-419037;Reactome: R-HSA-2243919;Reactome: R-HSA-1442490;Reactome: R-HSA-3000157;Reactome: R-HSA-186797;Reactome: R-HSA-3000178	"Integrin cell surface interactions";"Assembly of collagen fibrils and other multimeric structures";"Extracellular matrix organization";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"NCAM1 interactions";"Crosslinking of collagen fibrils";"Collagen degradation";"Laminin interactions";"Signaling by PDGF";"ECM proteoglycans"
XP_053613520.1	10	MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.15	"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Glycerolipid metabolism"
XP_053624933.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_053618438.1	17	Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs"
XP_053618510.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_053621221.1	7	Reactome: R-HSA-1474151;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3;MetaCyc: PWY-6614;MetaCyc: PWY-3841;Reactome: R-HSA-69205	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate biosynthesis";"Tetrahydrofolate biosynthesis";"Folate transformations II (plants)";"G1/S-Specific Transcription"
XP_053624897.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_053618673.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430	"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling"
XP_053605035.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844	"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_053607244.1	3	Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429947	"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA"
XP_053611981.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053611775.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-442982	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_053625422.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053624143.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-76042	"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_053614207.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053608620.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_053611352.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_053603458.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_053606400.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053625605.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053609740.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053624116.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_053608464.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053609547.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053613071.1	5	Reactome: R-HSA-73621;MetaCyc: PWY-5532;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3	"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_053604555.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_053604635.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053610806.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_053620952.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_053617517.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053611954.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053621005.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_053615309.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053600020.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_053619214.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053620381.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053625739.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053608097.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_053599537.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053625213.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053605224.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053601555.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053601918.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_053599730.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_053602224.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_053608351.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053612556.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_053600149.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053613304.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053606985.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053607627.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_053617667.1	3	Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1	"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism"
XP_053603194.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_053601047.1	1	Reactome: R-HSA-419771	"Opsins"
XP_053606114.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053599829.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053609732.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_053620296.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_053603229.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_053614036.1	6	MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7290	"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_053603390.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-399997	"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion"
XP_053612417.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053613155.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_053612738.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053621745.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053602649.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041	"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis"
XP_053614484.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053623041.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053622308.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053604680.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053625542.1	2	Reactome: R-HSA-5689880;MetaCyc: PWY-7511	"Ub-specific processing proteases";"Protein ubiquitination"
XP_053618233.1	6	MetaCyc: PWY-7790;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7791;Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10	"UMP biosynthesis II";"Drug metabolism - other enzymes";"UMP biosynthesis III";"Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism"
XP_053624899.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_053620592.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053610475.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"Oxidative Stress Induced Senescence"
XP_053613830.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053612724.1	4	MetaCyc: PWY-6483;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119	"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_053602764.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053611594.1	56	Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-4608870	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Degradation of DVL";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins"
XP_053614209.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053614815.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053605764.1	4	MetaCyc: PWY-7174;Reactome: R-HSA-72731;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_053604120.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053615252.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053599853.1	26	Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-8866907;Reactome: R-HSA-918233;Reactome: R-HSA-2894862;Reactome: R-HSA-3134973;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-3899300;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-9617629;Reactome: R-HSA-933541;Reactome: R-HSA-3214847;Reactome: R-HSA-5621575	"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Activation of the TFAP2 (AP-2) family of transcription factors";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"Estrogen-dependent gene expression";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of FOXO transcriptional activity by acetylation";"TRAF6 mediated IRF7 activation";"HATs acetylate histones";"CD209 (DC-SIGN) signaling"
XP_053610946.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053603253.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_053609549.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_053620525.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053614364.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_053623626.1	10	Reactome: R-HSA-380972;Reactome: R-HSA-200425;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209	"Energy dependent regulation of mTOR by LKB1-AMPK";"Carnitine metabolism";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
XP_053615307.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053609453.1	12	KEGG: 00230+6.3.3.1;MetaCyc: PWY-6277;KEGG: 00230+2.1.2.2;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6613;KEGG: 00670+2.1.2.2;Reactome: R-HSA-196780;MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00970+2.1.2.9;KEGG: 00230+6.3.4.13	"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Biotin transport and metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Aminoacyl-tRNA biosynthesis";"Purine metabolism"
XP_053606029.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053621346.1	14	Reactome: R-HSA-380259;Reactome: R-HSA-428890;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2565942;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Loss of Nlp from mitotic centrosomes";"Role of ABL in ROBO-SLIT signaling";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of PLK1 Activity at G2/M Transition";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_053619240.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_053620043.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053625418.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053608099.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053625530.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053606455.1	13	KEGG: 00053+1.8.5.1;MetaCyc: PWY-7533;MetaCyc: PWY-7112;MetaCyc: PWY-2261;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-196836;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;Reactome: R-HSA-156590;MetaCyc: PWY-6370	"Ascorbate and aldarate metabolism";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Ascorbate glutathione cycle";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Glutathione metabolism";"Vitamin C (ascorbate) metabolism";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Ascorbate recycling (cytosolic)"
XP_053625650.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053611364.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053600893.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-3232118;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565	"G2/M DNA damage checkpoint";"SUMOylation of transcription factors";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053621313.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053601324.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053604500.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-6803207;Reactome: R-HSA-8953750;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-111464	"Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Transcriptional Regulation by E2F6";"Regulation of the apoptosome activity";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_053599539.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_053615276.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_053602843.1	21	MetaCyc: PWY-7227;MetaCyc: PWY-7197;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7219;MetaCyc: PWY-7220;MetaCyc: PWY-7210;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7224;MetaCyc: PWY-7187;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7226;MetaCyc: PWY-7222;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7221;MetaCyc: PWY-7184;MetaCyc: PWY-6545	"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"CMP phosphorylation";"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Thiamine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_053611484.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053604078.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053616991.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_053600147.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053622093.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053601338.1	8	MetaCyc: PWY-5;MetaCyc: PWY-4983;MetaCyc: PWY-7400;KEGG: 00250+6.3.4.5;Reactome: R-HSA-70635;MetaCyc: PWY-4984;MetaCyc: PWY-5154;KEGG: 00220+6.3.4.5	"Canavanine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"Urea cycle";"Urea cycle";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Arginine biosynthesis"
XP_053624403.1	13	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-416476;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5687128;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"Human papillomavirus infection";"Thermogenesis";"MAPK6/MAPK4 signaling";"Relaxin signaling pathway";"EPHB-mediated forward signaling";"PI3K-Akt signaling pathway";"Rho GTPase cycle"
XP_053618877.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695	"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"MAP2K and MAPK activation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation"
XP_053599827.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053624693.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_053617669.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053607629.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_053599971.1	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
XP_053600319.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_053623065.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_053603227.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_053606124.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053601934.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_053601072.1	40	Reactome: R-HSA-168325;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-6803529;Reactome: R-HSA-6796648;Reactome: R-HSA-8851708;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-5617472;Reactome: R-HSA-75955;Reactome: R-HSA-203927;Reactome: R-HSA-167200;Reactome: R-HSA-5578749;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-6782135;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-5601884;Reactome: R-HSA-6781823;Reactome: R-HSA-167160;Reactome: R-HSA-75953	"Viral Messenger RNA Synthesis";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"FGFR2 alternative splicing";"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by FGFR2 IIIa TM";"mRNA Capping";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Elongation";"MicroRNA (miRNA) biogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation"
XP_053599819.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627	"Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_053624359.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053618100.1	2	Reactome: R-HSA-389397;Reactome: R-HSA-416476	"Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events"
XP_053607084.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_053625302.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_053608390.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_053615983.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053611535.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053608229.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_053625548.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053608194.1	16	Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-5685942	"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Estrogen-dependent gene expression";"HATs acetylate histones";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Homologous Recombination (HRR)"
XP_053619375.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053624506.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053606684.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053602214.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_053625223.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_053602656.1	5	Reactome: R-HSA-6798695;KEGG: 00030+4.1.2.4;MetaCyc: PWY-8060;MetaCyc: PWY-7180;Reactome: R-HSA-71336	"Neutrophil degranulation";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway"
XP_053623847.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053610671.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053619752.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_053615258.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
YP_009166941.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_053616033.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053601287.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053625931.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_053620191.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053614968.1	5	KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Stachyose degradation";"Glycerolipid metabolism";"Sphingolipid metabolism"
XP_053600353.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_053601056.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053613424.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053619035.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_053599570.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism"
XP_053618520.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids"
XP_053606979.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053625579.1	5	Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053599613.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053621359.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053602469.1	2	Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis"
XP_053614535.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053617633.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053616797.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053617553.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053610597.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_053625141.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053622086.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053602672.1	5	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation"
XP_053610790.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902	"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation"
XP_053599646.1	11	MetaCyc: PWY-5381;MetaCyc: PWY-6606;MetaCyc: PWY-6608;MetaCyc: PWY-6607;KEGG: 00760+3.1.3.5;MetaCyc: PWY-5695;MetaCyc: PWY-6596;MetaCyc: PWY-7821;KEGG: 00230+3.1.3.5;MetaCyc: PWY-7185;KEGG: 00240+3.1.3.5	"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation I";"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I";"Tunicamycin biosynthesis";"Purine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism"
XP_053601332.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053623396.1	18	KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6728;Reactome: R-HSA-163765;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5913;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5172;KEGG: 00640+6.2.1.5;Reactome: R-HSA-6798695;MetaCyc: PWY-5392;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;Reactome: R-HSA-75105;MetaCyc: PWY-5537;MetaCyc: PWY-6969	"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"ChREBP activates metabolic gene expression";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"Propanoate metabolism";"Neutrophil degranulation";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Fatty acyl-CoA biosynthesis";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_053607619.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053619433.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_053612866.1	6	MetaCyc: PWY-7238;MetaCyc: PWY-6731;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.1;MetaCyc: PWY-5941;Reactome: R-HSA-70221	"Sucrose biosynthesis II";"Starch degradation III";"Starch degradation V";"Starch and sucrose metabolism";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)"
XP_053599817.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-2022854;Reactome: R-HSA-5173105	"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis";"O-linked glycosylation"
XP_053602826.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053600290.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_053625434.1	11	MetaCyc: PWY-7254;MetaCyc: PWY-6549;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-7124;Reactome: R-HSA-71403;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.42;KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6969	"TCA cycle VII (acetate-producers)";"L-glutamine biosynthesis III";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Ethylene biosynthesis V (engineered)";"Citric acid cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_053608227.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_053626062.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053610204.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053616435.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_053616950.1	12	Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-6142;KEGG: 00680+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13	"Glycolysis";"Fructose and mannose metabolism";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms"
XP_053620641.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_053613908.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053617993.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053618432.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_053622428.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053625401.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_053601110.1	3	Reactome: R-HSA-3214858;Reactome: R-HSA-191859;Reactome: R-HSA-6804760	"RMTs methylate histone arginines";"snRNP Assembly";"Regulation of TP53 Activity through Methylation"
XP_053611892.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053600044.1	7	Reactome: R-HSA-1483148;MetaCyc: PWY-7039;MetaCyc: PWY-3561;Reactome: R-HSA-1483166;KEGG: 00565+3.1.4.4;Reactome: R-HSA-2029485;KEGG: 00564+3.1.4.4	"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Synthesis of PA";"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism"
XP_053625428.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053620894.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053611787.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-442982	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_053623849.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_053615453.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053615578.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053617529.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053603099.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_053611825.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053611358.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053612578.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053607220.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053618440.1	16	Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-1234176;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-180585;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-8951664	"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Vif-mediated degradation of APOBEC3G";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Neddylation"
XP_053609724.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_053608253.1	9	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway"
XP_053601841.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_053612171.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053600963.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7587;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51	"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism"
XP_053615714.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_053622763.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_053621091.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053607436.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_053625770.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_053621357.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053607813.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053625577.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-1912420	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi"
XP_053603476.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053615427.1	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_053602467.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053619649.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053611600.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_053609996.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_053625590.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053621527.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_053621720.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053616086.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053625905.1	10	Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-200425;Reactome: R-HSA-1445148;Reactome: R-HSA-380972	"Activation of AMPK downstream of NMDARs";"Lipophagy";"TP53 Regulates Metabolic Genes";"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Carnitine metabolism";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_053608348.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053600997.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053619028.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053622882.1	33	Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-159236;Reactome: R-HSA-159230	"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA"
XP_053616257.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053625882.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053617126.1	5	MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis"
XP_053611681.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053624478.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053618973.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053599923.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_053624633.1	9	MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-241;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_053616412.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_053623575.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_053624553.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053609241.1	6	KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122	"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis"
XP_053602947.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_053620540.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_053616931.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053619034.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_053621478.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_053618293.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053606685.1	15	KEGG: 00620+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-2221;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-8004	"Pyruvate metabolism";"Rubisco shunt";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I"
XP_053625373.1	8	MetaCyc: PWY-4984;KEGG: 00220+4.3.2.1;MetaCyc: PWY-5;Reactome: R-HSA-70635;MetaCyc: PWY-4983;MetaCyc: PWY-7400;KEGG: 00250+4.3.2.1;MetaCyc: PWY-5154	"Urea cycle";"Arginine biosynthesis";"Canavanine biosynthesis";"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)"
XP_053625480.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-5368286;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis"
XP_053607927.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053622480.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053621553.1	8	Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7391;MetaCyc: PWY-7524;Reactome: R-HSA-1989781	"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"PPARA activates gene expression"
XP_053605215.1	17	Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-69183;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-174414;Reactome: R-HSA-174417;Reactome: R-HSA-6782210	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Polymerase switching";"Processive synthesis on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_053619170.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_053607871.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053604161.1	4	KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5041;MetaCyc: PWY-5912	"Cysteine and methionine metabolism";"Methylation";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis"
XP_053601003.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053616223.1	6	MetaCyc: PWY-6368;Reactome: R-HSA-1660499;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.64+3.1.3.95;MetaCyc: PWY-6580;KEGG: 00562+3.1.3.64+3.1.3.95	"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism"
XP_053611528.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053601145.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053603441.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"HCMV Early Events";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_053601935.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_053612081.1	30	Reactome: R-HSA-76042;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-2564830;Reactome: R-HSA-167160;Reactome: R-HSA-5696400;Reactome: R-HSA-75953;Reactome: R-HSA-5696395;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6781827	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"Cytosolic iron-sulfur cluster assembly";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_053606125.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053599957.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_053616165.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053606270.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_053600639.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.14	"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053607085.1	8	MetaCyc: PWY-6545;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7187	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_053611654.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053606192.1	33	KEGG: 00626+1.1.1.1;MetaCyc: PWY-7013;MetaCyc: PWY-5076;Reactome: R-HSA-71384;MetaCyc: PWY-6342;MetaCyc: PWY-7798;MetaCyc: PWY-7118;MetaCyc: PWY-5078;MetaCyc: PWY-7111;MetaCyc: PWY-6871;MetaCyc: PWY-5079;KEGG: 00010+1.1.1.1;KEGG: 00980+1.1.1.1;MetaCyc: PWY-1801;MetaCyc: PWY-5057;MetaCyc: PWY-5082;KEGG: 00071+1.1.1.1;MetaCyc: PWY-7396;MetaCyc: PWY-6313;MetaCyc: PWY-5751;MetaCyc: PWY-6587;MetaCyc: PWY-5480;KEGG: 00830+1.1.1.1;KEGG: 00592+1.1.1.1;KEGG: 00350+1.1.1.1;KEGG: 00680+1.1.1.284;MetaCyc: PWY-6802;KEGG: 00625+1.1.1.1;MetaCyc: PWY-3162;KEGG: 00982+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-6333;KEGG: 00260+1.1.1.1	"Naphthalene degradation";"(S)-propane-1,2-diol degradation";"L-leucine degradation III";"Ethanol oxidation";"Noradrenaline and adrenaline degradation";"Protein S-nitrosylation and denitrosylation";"Chitin degradation to ethanol";"L-isoleucine degradation II";"Pyruvate fermentation to isobutanol (engineered)";"3-methylbutanol biosynthesis (engineered)";"L-phenylalanine degradation III";"Glycolysis / Gluconeogenesis";"Metabolism of xenobiotics by cytochrome P450";"Formaldehyde oxidation II (glutathione-dependent)";"L-valine degradation II";"L-methionine degradation III";"Fatty acid degradation";"Butanol and isobutanol biosynthesis (engineered)";"Serotonin degradation";"Phenylethanol biosynthesis";"Pyruvate fermentation to ethanol III";"Pyruvate fermentation to ethanol I";"Retinol metabolism";"alpha-Linolenic acid metabolism";"Tyrosine metabolism";"Methane metabolism";"Salidroside biosynthesis";"Chloroalkane and chloroalkene degradation";"L-tryptophan degradation V (side chain pathway)";"Drug metabolism - cytochrome P450";"Pyruvate fermentation to ethanol II";"Acetaldehyde biosynthesis I";"Glycine, serine and threonine metabolism"
XP_053608195.1	16	Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-201722;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568	"HATs acetylate histones";"Estrogen-dependent gene expression";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Formation of the beta-catenin:TCF transactivating complex";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053620532.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053603112.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_053622360.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053618350.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_053603101.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053602139.1	4	Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-77075	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_053625799.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_053619596.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_053614838.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_053600248.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_053622152.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053616259.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053624260.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053608118.1	57	Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-6798695;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-983168	"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of GLI1 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053616770.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-381183	"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_053606642.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053617202.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_053607174.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053607483.1	57	Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-6798695;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-9604323	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Neutrophil degranulation";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling"
XP_053607370.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_053609725.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_053612406.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_053615715.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_053613286.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053611096.1	3	Reactome: R-HSA-4086398;Reactome: R-HSA-392517;Reactome: R-HSA-418457	"Ca2+ pathway";"Rap1 signalling";"cGMP effects"
XP_053618608.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053622176.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
XP_053608661.1	2	Reactome: R-HSA-9627069;Reactome: R-HSA-111458	"Regulation of the apoptosome activity";"Formation of apoptosome"
XP_053620895.1	4	MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_053624993.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163359	"PKA activation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Hedgehog 'off' state";"G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation"
XP_053618621.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053607929.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053599671.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053617969.1	11	Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-9018519;Reactome: R-HSA-6804114;Reactome: R-HSA-3214858;Reactome: R-HSA-381340	"Circadian Clock";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RMTs methylate histone arginines";"Transcriptional regulation of white adipocyte differentiation"
XP_053606388.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053616844.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053605022.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053599959.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_053603508.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_053600557.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER"
XP_053607593.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;Reactome: R-HSA-189085	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate"
XP_053613561.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_053603521.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_053613023.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053625435.1	11	KEGG: 00720+1.1.1.42;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7268;Reactome: R-HSA-71403;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-7254;MetaCyc: PWY-6549	"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citric acid cycle (TCA cycle)";"Glutathione metabolism";"Ethylene biosynthesis V (engineered)";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"L-glutamine biosynthesis III"
XP_053625950.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_053604622.1	6	MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221	"Sorbitol biosynthesis II";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_053620007.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053605163.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053616585.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053610785.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053612123.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053609113.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053603122.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_053613305.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053601628.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_053611668.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053603195.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_053606984.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053601601.1	3	KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
XP_053618890.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_053606115.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053622158.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053607339.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_053624517.1	26	Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-190840	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Kinesins";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane"
XP_053623803.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053605292.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053609798.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-73856	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination"
XP_053602292.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_053611518.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053617208.1	6	MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11	"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism"
XP_053606648.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053616213.1	12	Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-73762;Reactome: R-HSA-3214847;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-5250924;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RNA Polymerase I Transcription Initiation";"HATs acetylate histones";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"B-WICH complex positively regulates rRNA expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_053619215.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_053623589.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_053602170.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053616246.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_053601554.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053622067.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_053602225.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_053613415.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_053605034.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430	"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle"
XP_053607245.1	3	Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429947	"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA"
XP_053615157.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053616495.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053599946.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_053619947.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053611774.1	2	Reactome: R-HSA-442982;Reactome: R-HSA-5673001	"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade"
XP_053622604.1	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_053599913.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053600230.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_053625604.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053612241.1	16	Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-176412	"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Phosphorylation of the APC/C"
XP_053618425.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_053608465.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053620355.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053624986.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-5461	"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Betanidin degradation"
XP_053619603.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_053604554.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_053611442.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053614226.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053604266.1	4	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;KEGG: 00790+4.6.1.17	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis"
XP_053608385.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053607079.1	2	MetaCyc: PWY-7533;Reactome: R-HSA-1268020	"Gliotoxin biosynthesis";"Mitochondrial protein import"
XP_053612503.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053623499.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053604601.1	3	MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_053623609.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_053604628.1	6	MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221	"Sorbitol biosynthesis II";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_053625551.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053603920.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695	"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_053621517.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_053617143.1	5	KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;MetaCyc: PWY-6558;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis"
XP_053612326.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_053608063.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053610829.1	9	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-110314	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Recognition of DNA damage by PCNA-containing replication complex"
XP_053611485.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053604612.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_053607337.1	10	Reactome: R-HSA-182971;Reactome: R-HSA-9636383;Reactome: R-HSA-8856825;Reactome: R-HSA-5689880;Reactome: R-HSA-6807004;Reactome: R-HSA-432720;Reactome: R-HSA-917729;Reactome: R-HSA-9635644;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360	"EGFR downregulation";"Prevention of phagosomal-lysosomal fusion";"Cargo recognition for clathrin-mediated endocytosis";"Ub-specific processing proteases";"Negative regulation of MET activity";"Lysosome Vesicle Biogenesis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Inhibition of membrane repair";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_053617050.1	8	MetaCyc: PWY-6611;Reactome: R-HSA-5683826;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;Reactome: R-HSA-74217	"Adenine and adenosine salvage V";"Surfactant metabolism";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine salvage"
XP_053622991.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_053619022.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_053620131.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053624519.1	26	Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-389960;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148	"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HCMV Early Events";"Gap junction assembly";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"Formation of tubulin folding intermediates by CCT/TriC";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"RHO GTPases activate IQGAPs";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"Post-chaperonin tubulin folding pathway";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053613621.1	8	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9633012	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053610730.1	3	Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-6785807	"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"Interleukin-4 and Interleukin-13 signaling"
XP_053617693.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053605741.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053624472.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053603206.1	3	KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00230+1.7.3.3	"Caffeine metabolism";"Urate conversion to allantoin I";"Purine metabolism"
XP_053614341.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_053623587.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_053606454.1	5	Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69205	"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"G1/S-Specific Transcription"
XP_053618611.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_053601325.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053622069.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_053621669.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053604392.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053610474.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-450341	"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors"
XP_053615887.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053610183.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053612725.1	3	MetaCyc: PWY-5996;MetaCyc: PWY-5987;Reactome: R-HSA-75105	"Oleate biosynthesis II (animals and fungi)";"Sorgoleone biosynthesis";"Fatty acyl-CoA biosynthesis"
XP_053615725.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053606746.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053619298.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053611341.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_053601562.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053606239.1	4	Reactome: R-HSA-1971475;KEGG: 00532+2.4.2.26;KEGG: 00534+2.4.2.26;MetaCyc: PWY-6557	"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan-protein linkage region biosynthesis"
XP_053607721.1	5	MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"D-galactose detoxification";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism"
XP_053614102.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053620524.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_053607708.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053614365.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_053613154.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation"
XP_053601612.1	4	KEGG: 00510+2.4.1.258;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.258;Reactome: R-HSA-4720475	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)"
XP_053608101.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053614485.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053607077.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_053606361.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053623607.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_053602596.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_053603118.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_053601726.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053620538.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053611766.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053620410.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053606198.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_053622271.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_053609818.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053609676.1	11	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-3371497	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_053612801.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_053607982.1	6	MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433	"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_053614200.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053602868.1	9	KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-6549;MetaCyc: PWY-6963;MetaCyc: PWY-381;MetaCyc: PWY-6964;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2	"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)";"L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle II";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism"
XP_053611575.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_053623121.1	3	Reactome: R-HSA-349425;MetaCyc: PWY-7511;Reactome: R-HSA-8951664	"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination";"Neddylation"
XP_053607733.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053623108.1	12	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-381038;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"XBP1(S) activates chaperone genes";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_053603906.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_053606407.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_053612772.1	7	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-114608;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-140837;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"Platelet degranulation";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Intrinsic Pathway of Fibrin Clot Formation";"G alpha (q) signalling events"
XP_053604755.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053613449.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_053607219.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053609540.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_053613720.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_053610631.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_053613527.1	7	KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897;MetaCyc: PWY-5921	"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation"
XP_053605640.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_053604040.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_053601356.1	14	Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-5656169	"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis"
XP_053615444.1	12	MetaCyc: PWY-7817;MetaCyc: PWY-7238;KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00561+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00500+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7343;Reactome: R-HSA-3322077;MetaCyc: PWY-3801;KEGG: 00052+2.7.7.9	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Glycerolipid metabolism";"Stachyose degradation";"Starch and sucrose metabolism";"Pentose and glucuronate interconversions";"UDP-alpha-D-glucose biosynthesis I";"Glycogen synthesis";"Sucrose degradation II (sucrose synthase)";"Galactose metabolism"
XP_053623681.1	14	MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-2221;MetaCyc: PWY-1622;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-6886;MetaCyc: PWY-6142;KEGG: 00010+4.2.1.11;MetaCyc: PWY-8004;MetaCyc: PWY-7124;MetaCyc: PWY-1042	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)"
XP_053624890.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_053610158.1	3	KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347	"Glycine, serine and threonine metabolism";"Methane metabolism";"Serine biosynthesis"
XP_053619075.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_053607620.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053600114.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053600985.1	7	Reactome: R-HSA-5578999;MetaCyc: PWY-6840;Reactome: R-HSA-174403;MetaCyc: PWY-7255;KEGG: 00480+6.3.2.2;KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Homoglutathione biosynthesis";"Glutathione synthesis and recycling";"Ergothioneine biosynthesis I (bacteria)";"Glutathione metabolism";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis"
XP_053601040.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053625785.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053625971.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_053606317.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_053600771.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_053603397.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053622971.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_053617673.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_053601372.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_053613478.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053613553.1	4	KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;Reactome: R-HSA-1614603	"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine"
XP_053619249.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_053611200.1	4	KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817	"Purine metabolism";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis"
XP_053610067.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053617717.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662	"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling"
XP_053600027.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053624059.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_053622002.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053618986.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_053625539.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053625002.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_053619881.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053607180.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053599737.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_053604974.1	9	KEGG: 00550+2.4.1.227;Reactome: R-HSA-5633231;MetaCyc: PWY-5265;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.141;MetaCyc: PWY-6471;KEGG: 00513+2.4.1.141;MetaCyc: PWY-6385;MetaCyc: PWY-6470	"Peptidoglycan biosynthesis";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Various types of N-glycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis V (beta-lactam resistance)"
XP_053602992.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_053605992.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_053609236.1	6	MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7290	"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_053620792.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_053615524.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053608629.1	5	MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68;Reactome: R-HSA-975578	"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"Reactions specific to the complex N-glycan synthesis pathway"
XP_053616913.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053611255.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053621057.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_053611794.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053617908.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_053602564.1	5	KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2	"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)"
XP_053622011.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053619558.1	6	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.3;Reactome: R-HSA-446210;MetaCyc: PWY-5514;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism"
XP_053606409.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_053619915.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_053601507.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_053612965.1	22	MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7727;MetaCyc: PWY-7606;MetaCyc: PWY-7725;MetaCyc: PWY-7728;MetaCyc: PWY-7053;MetaCyc: PWY-6598;MetaCyc: PWY-5353;MetaCyc: PWY-7049;MetaCyc: PWY-7592;MetaCyc: PWY-6958;MetaCyc: PWY-7035;MetaCyc: PWY-6433;KEGG: 00062+4.2.1.134;Reactome: R-HSA-75876;MetaCyc: PWY-7726;MetaCyc: PWY-7619;MetaCyc: PWY-5080	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I"
XP_053599605.1	10	Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2197563;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606	"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_053625183.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053607217.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053609749.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_053619380.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053615965.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053613447.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_053619473.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053621168.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_053621545.1	10	Reactome: R-HSA-9022699;Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-400206;Reactome: R-HSA-9022702;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-9022538	"MECP2 regulates neuronal receptors and channels";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates transcription of neuronal ligands";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to 5mC-DNA"
XP_053612410.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_053616136.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053612658.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053607099.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053624561.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053618519.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946	"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin"
XP_053601153.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_053605256.1	11	Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-112382	"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex"
XP_053609664.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_053619624.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_053622742.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214	"Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs"
XP_053614058.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053624545.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053624168.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053608210.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053599820.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854	"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis"
XP_053618870.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-5221030;Reactome: R-HSA-3108214	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins"
XP_053620326.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_053603399.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_053624391.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_053599585.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053606319.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_053626016.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053607945.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053612104.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053615104.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053617233.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053600029.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053603846.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053619247.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_053602190.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_053622657.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-171319	"HATs acetylate histones";"Telomere Extension By Telomerase"
XP_053603436.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_053605190.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_053611167.1	20	Reactome: R-HSA-3371571;Reactome: R-HSA-5218920;Reactome: R-HSA-9639288;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-6804757;Reactome: R-HSA-165159;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;KEGG: 05163+2.7.11.1	"HSF1-dependent transactivation";"VEGFR2 mediated vascular permeability";"Amino acids regulate mTORC1";"PI3K-Akt signaling pathway";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Human papillomavirus infection";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of TP53 Degradation";"mTOR signalling";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"Human cytomegalovirus infection"
XP_053617544.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_053623824.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_053599739.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_053619862.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_053609822.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_053607476.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053606893.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053611076.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_053608051.1	7	MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-6545;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7185;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Thiamine metabolism";"UTP and CTP dephosphorylation I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_053618633.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053599691.1	19	Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-3214858;Reactome: R-HSA-72689;Reactome: R-HSA-8876725;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902	"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"RMTs methylate histone arginines";"Formation of a pool of free 40S subunits";"Protein methylation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation"
XP_053602998.1	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_053620936.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_053623840.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_053601347.1	14	Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801	"Translesion synthesis by REV1";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair"
XP_053616671.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_053611589.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_053610480.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_053607560.1	8	Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724	"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription"
XP_053619632.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053614336.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053624884.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_053600124.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053603533.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_053613031.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053621305.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053612652.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_053600948.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053617414.1	4	KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;Reactome: R-HSA-196757	"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Metabolism of folate and pterines"
XP_053608397.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_053625748.1	12	Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167200	"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_053611735.1	9	KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-241;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-5744	"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation"
XP_053623668.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053603244.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_053614609.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_053616959.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053609756.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053618527.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_053608760.1	3	MetaCyc: PWY-7892;Reactome: R-HSA-6787450;MetaCyc: PWY-7887	"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation"
XP_053605335.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053600504.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_053624162.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053624851.1	6	Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695	"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism";"Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation"
XP_053619576.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053603859.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_053625779.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_053619640.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_053613517.1	15	Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585	"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence"
XP_053613371.1	8	KEGG: 00564+3.1.3.27;KEGG: 05235+3.1.3.16;MetaCyc: PWY-7817;KEGG: 04658+3.1.3.16;MetaCyc: PWY-5668;MetaCyc: PWY-5269;Reactome: R-HSA-1483148;KEGG: 04660+3.1.3.16	"Glycerophospholipid metabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Th1 and Th2 cell differentiation";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"Synthesis of PG";"T cell receptor signaling pathway"
XP_053623832.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053621706.1	8	KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053604119.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053614076.1	22	Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5339716;Reactome: R-HSA-2500257;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-432142	"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"RAF activation";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Resolution of Sister Chromatid Cohesion";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL"
XP_053621415.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053600651.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053610033.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_053600531.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362300	"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_053606353.1	5	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_053607229.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-1679131;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"MHC class II antigen presentation";"Neutrophil degranulation";"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_053617100.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053599763.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-400511	"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_053604347.1	5	KEGG: 00280+1.2.4.4;MetaCyc: PWY-5046;Reactome: R-HSA-389661;Reactome: R-HSA-70895;KEGG: 00640+1.2.4.4	"Valine, leucine and isoleucine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism"
XP_053619868.1	5	MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18	"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism"
XP_053623083.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053608773.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_053611336.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053608617.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_053615676.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053621608.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_053602862.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725	"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_053601117.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_053609941.1	20	Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-176187;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-5696400;Reactome: R-HSA-6804756	"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Polymerase switching";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of ATR in response to replication stress";"Translesion synthesis by POLK";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"Dual Incision in GG-NER";"Regulation of TP53 Activity through Phosphorylation"
XP_053613863.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053604378.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_053626026.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-6798695	"WNT ligand biogenesis and trafficking";"Neutrophil degranulation"
XP_053601349.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_053611780.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-442982	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_053612778.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_053609104.1	3	Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999	"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
XP_053619272.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_053623102.1	12	Reactome: R-HSA-381038;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-2132295	"XBP1(S) activates chaperone genes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation"
XP_053617729.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_053600019.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053615895.1	13	MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;Reactome: R-HSA-2160916	"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Other glycan degradation";"CS/DS degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation"
XP_053624588.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053599810.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854	"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis"
XP_053610845.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_053614943.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053600297.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_053606329.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_053607253.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053625205.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053625819.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_053621181.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053614916.1	6	MetaCyc: PWY-7900;MetaCyc: PWY-5067;Reactome: R-HSA-189085;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch biosynthesis";"Starch and sucrose metabolism";"Starch and sucrose metabolism"
XP_053608220.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053608399.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_053616957.1	14	Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-1632852;Reactome: R-HSA-5620924;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Macroautophagy";"Intraflagellar transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HCMV Early Events"
XP_053607644.1	6	MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-2173788;Reactome: R-HSA-8863795;Reactome: R-HSA-983168;Reactome: R-HSA-8939902	"Protein ubiquitination";"Regulation of PTEN stability and activity";"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity"
XP_053611064.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053610435.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_053613870.1	3	Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361	"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_053611943.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053613744.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_053615664.1	12	KEGG: 00680+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-5133;MetaCyc: PWY-6672;MetaCyc: PWY-7857;KEGG: 00720+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-5108	"Methane metabolism";"Propanoate metabolism";"Chitin degradation to ethanol";"Glycolysis / Gluconeogenesis";"Lupulone and humulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Cis-genanyl-coa degradation";"Adlupulone and adhumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"L-isoleucine biosynthesis V"
XP_053618529.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68616	"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication"
XP_053625777.1	7	Reactome: R-HSA-203927;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-1655829;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-168333	"MicroRNA (miRNA) biogenesis";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_053600821.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053603189.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER"
XP_053615420.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053614064.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053613519.1	15	Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408	"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation"
XP_053609658.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053618993.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_053615749.1	33	Reactome: R-HSA-167158;Reactome: R-HSA-8939236;Reactome: R-HSA-69202;Reactome: R-HSA-69231;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-69656;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-69273;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-427413;Reactome: R-HSA-6782210;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167152	"Formation of the HIV-1 Early Elongation Complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin E associated events during G1/S transition";"Cyclin D associated events in G1";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin A:Cdk2-associated events at S phase entry";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"NoRC negatively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_053612749.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis"
XP_053603629.1	3	KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581;MetaCyc: PWY-5963	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis"
XP_053602380.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_053604117.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053602558.1	5	KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2	"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)"
XP_053618837.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053601378.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053620696.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_053599931.1	6	Reactome: R-HSA-73930;Reactome: R-HSA-73933;Reactome: R-HSA-110362;Reactome: R-HSA-110373;Reactome: R-HSA-5651801;Reactome: R-HSA-110357	"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of Abasic Sites (AP sites)";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1"
XP_053602915.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163615	"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation"
XP_053620406.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053607227.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053605638.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053609524.1	15	Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167200	"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_053623522.1	6	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-8939211;Reactome: R-HSA-5693565	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"ESR-mediated signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053619992.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_053616923.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053612236.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053608619.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053603048.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053614872.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053621414.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053607379.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_053608085.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_053605328.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_053620547.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053602940.1	16	Reactome: R-HSA-1250347;Reactome: R-HSA-1227986;Reactome: R-HSA-5673001;Reactome: R-HSA-8847993;Reactome: R-HSA-9664565;Reactome: R-HSA-6785631;Reactome: R-HSA-1963640;Reactome: R-HSA-1963642;Reactome: R-HSA-1250342;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795;Reactome: R-HSA-1251985;Reactome: R-HSA-1236394;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-1250196	"SHC1 events in ERBB4 signaling";"Signaling by ERBB2";"RAF/MAP kinase cascade";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Regulates Cell Motility";"GRB2 events in ERBB2 signaling";"PI3K events in ERBB2 signaling";"PI3K events in ERBB4 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling";"Nuclear signaling by ERBB4";"Signaling by ERBB4";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB2 signaling"
XP_053612191.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053623352.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_053614701.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053621071.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053606997.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053610086.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053600505.1	17	Reactome: R-HSA-5693565;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756;Reactome: R-HSA-3270619;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-1834949	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation";"IRF3-mediated induction of type I IFN";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Cytosolic sensors of pathogen-associated DNA"
XP_053624304.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053603606.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053602130.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_053625790.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_053599861.1	26	Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-9617629;Reactome: R-HSA-933541;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-3899300;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-3134973;Reactome: R-HSA-918233;Reactome: R-HSA-8866907;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408	"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of FOXO transcriptional activity by acetylation";"TRAF6 mediated IRF7 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SUMOylation of transcription cofactors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"Estrogen-dependent gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"TRAF3-dependent IRF activation pathway";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation"
XP_053614734.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_053603261.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_053602411.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_053624885.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_053610165.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_053623376.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053602783.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053625959.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053606639.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_053619408.1	10	MetaCyc: PWY-7411;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8055	"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis"
XP_053624520.1	26	Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-2132295	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Kinesins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Gap junction assembly";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation"
XP_053619421.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053600270.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_053617706.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053603245.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_053614856.1	10	KEGG: 00520+5.1.3.2;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;Reactome: R-HSA-70370;MetaCyc: PWY-7344;MetaCyc: PWY-6317;MetaCyc: PWY-6397;MetaCyc: PWY-6527;MetaCyc: PWY-3821	"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation";"D-galactose detoxification"
XP_053625367.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053613897.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7	"Betanidin degradation";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis"
XP_053610810.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation"
XP_053602932.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787	"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Hedgehog 'off' state"
XP_053606306.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_053621753.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053613005.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053607502.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_053603079.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513	"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_053611728.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053610223.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_053600263.1	6	MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5653;KEGG: 00760+6.3.5.1;KEGG: 00760+6.3.1.5	"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism"
XP_053611701.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053611712.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053609964.1	28	Reactome: R-HSA-110314;Reactome: R-HSA-5693616;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-176187;Reactome: R-HSA-6783310;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5693607;Reactome: R-HSA-3371511;Reactome: R-HSA-5656121;Reactome: R-HSA-3371453;Reactome: R-HSA-6782210;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5696395;Reactome: R-HSA-5358565;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-5696400;Reactome: R-HSA-5358606;Reactome: R-HSA-174437;Reactome: R-HSA-68962;Reactome: R-HSA-912446;Reactome: R-HSA-110320	"Recognition of DNA damage by PCNA-containing replication complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processing of DNA double-strand break ends";"HSF1 activation";"Translesion synthesis by POLI";"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in TC-NER";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Formation of Incision Complex in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate from the C-strand";"Activation of the pre-replicative complex";"Meiotic recombination";"Translesion Synthesis by POLH"
XP_053616563.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_053607511.1	6	KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-71403;Reactome: R-HSA-1268020;KEGG: 00020+4.2.1.3	"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Mitochondrial protein import";"Citrate cycle (TCA cycle)"
XP_053613050.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053610763.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053611268.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053620549.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053618091.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053619565.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867	"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex"
XP_053611626.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053599905.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053604092.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053622599.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_053624842.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_053625599.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053606999.1	2	KEGG: 00040+5.3.1.5;KEGG: 00051+5.3.1.5	"Pentose and glucuronate interconversions";"Fructose and mannose metabolism"
XP_053617621.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_053617498.1	8	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-6804115;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_053613403.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053601543.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_053611041.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053605402.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053605692.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-7445	"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation"
XP_053603282.1	1	Reactome: R-HSA-419771	"Opsins"
XP_053624267.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_053610311.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053602402.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053623173.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_053600388.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053600630.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_053606750.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_053603721.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053600757.1	3	KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590;MetaCyc: PWY-1801	"Methane metabolism";"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)"
XP_053607645.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_053622369.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_053610434.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_053611065.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053620000.1	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
XP_053622231.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_053606103.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_053620453.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_053602066.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_053602800.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053619179.1	4	Reactome: R-HSA-6807047;Reactome: R-HSA-6807062;KEGG: 00100+1.3.1.72;MetaCyc: PWY-8026	"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol";"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)"
XP_053604228.1	6	KEGG: 00730+2.7.6.2;Reactome: R-HSA-196819;MetaCyc: PWY-6908;MetaCyc: PWY-7356;MetaCyc: PWY-6898;MetaCyc: PWY-6907	"Thiamine metabolism";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage IV (yeast)";"Thiamine salvage III";"Thiamine diphosphate biosynthesis III (Staphylococcus)"
XP_053625489.1	3	KEGG: 00970+6.1.1.7;Reactome: R-HSA-5368286;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation";"Cytosolic tRNA aminoacylation"
XP_053610428.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_053600468.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_053616393.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053609105.1	3	MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K"
XP_053603077.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513	"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_053615894.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053613313.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-8963684;Reactome: R-HSA-156590	"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism";"Glutathione conjugation"
XP_053618143.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053616002.1	7	KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660514;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.67;MetaCyc: PWY-6351;Reactome: R-HSA-1660516	"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the early endosome membrane"
XP_053611262.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053609598.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053611718.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825	"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis"
XP_053604781.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_053608079.1	2	Reactome: R-HSA-2151201;KEGG: 00970+6.1.1.14	"Transcriptional activation of mitochondrial biogenesis";"Aminoacyl-tRNA biosynthesis"
XP_053602177.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-877300	"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"RAF activation";"Interferon gamma signaling"
XP_053604836.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053601754.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053612296.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053619932.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053619074.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053617425.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_053622073.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053604098.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053602408.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_053600115.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053603288.1	4	Reactome: R-HSA-2214320;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814	"Anchoring fibril formation";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes"
XP_053605698.1	7	Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-8950505;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-390471	"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053624673.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053625784.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-141444	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053618897.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053624510.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053619411.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053603702.1	5	MetaCyc: PWY-7082;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-6692;KEGG: 00190+7.1.1.8	"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Oxidative phosphorylation"
XP_053614193.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053613359.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers"
XP_053600382.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053607441.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053616291.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053608261.1	9	KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400	"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_053613967.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053607786.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053625751.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_053613506.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_053610495.1	14	Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-4302;KEGG: 00190+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-7254;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-7279;MetaCyc: PWY-6728;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"Butanoate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle";"Respiratory electron transport"
XP_053614262.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_053604222.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_053620572.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053601446.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053608339.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_053614718.1	7	MetaCyc: PWY-7176;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00983+2.7.4.14;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Drug metabolism - other enzymes";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_053607112.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_053611574.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_053610422.1	5	Reactome: R-HSA-3249367;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-1834941;Reactome: R-HSA-3134975	"STAT6-mediated induction of chemokines";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA"
XP_053602318.1	5	MetaCyc: PWY-6277;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121;Reactome: R-HSA-73817;MetaCyc: PWY-6122	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_053615362.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053623892.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053612105.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_053616537.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053610418.1	5	Reactome: R-HSA-3134975;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-3249367	"Regulation of innate immune responses to cytosolic DNA";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"STAT6-mediated induction of chemokines"
XP_053618346.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_053603042.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053604762.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053623580.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_053605179.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053617545.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_053608708.1	56	Reactome: R-HSA-4641258;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-174084	"Degradation of DVL";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_053624544.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053618761.1	13	Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-139853;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-114508;Reactome: R-HSA-983695	"PLC beta mediated events";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Elevation of cytosolic Ca2+ levels";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"Effects of PIP2 hydrolysis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"
XP_053607330.1	7	KEGG: 00230+4.3.2.2;MetaCyc: PWY-7219;MetaCyc: PWY-6123;Reactome: R-HSA-73817;MetaCyc: PWY-7234;KEGG: 00250+4.3.2.2;MetaCyc: PWY-6124	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis II"
XP_053609641.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053614566.1	3	Reactome: R-HSA-1660516;Reactome: R-HSA-1660517;Reactome: R-HSA-1660514	"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane"
XP_053604526.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053603174.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_053624233.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053613202.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053603483.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_053606791.1	3	KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695	"Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation"
XP_053601106.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053610093.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053621921.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_053599584.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053605203.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053626131.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_053621544.1	10	Reactome: R-HSA-3899300;Reactome: R-HSA-983231;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-9022702;Reactome: R-HSA-400206;Reactome: R-HSA-9615017	"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands";"Regulation of lipid metabolism by PPARalpha";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_053619692.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_053608919.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053616623.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_053610321.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053600361.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_053610542.1	3	Reactome: R-HSA-162658;Reactome: R-HSA-204005;Reactome: R-HSA-6807878	"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport"
XP_053613357.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_053605796.1	10	Reactome: R-HSA-201722;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5689880	"Formation of the beta-catenin:TCF transactivating complex";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"HATs acetylate histones";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Ub-specific processing proteases"
XP_053608282.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053599631.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053620738.1	4	Reactome: R-HSA-428540;Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-186763	"Activation of RAC1";"Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Downstream signal transduction"
XP_053609665.1	56	Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-4641258;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-68827	"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Degradation of DVL";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex"
XP_053618693.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_053603929.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72649	"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation"
XP_053612880.1	17	MetaCyc: PWY-7226;MetaCyc: PWY-7176;MetaCyc: PWY-7187;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7184;MetaCyc: PWY-6545;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7227;MetaCyc: PWY-7224;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6	"Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Pyrimidine metabolism"
XP_053618050.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053611254.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_053625946.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
YP_009166936.1	7	MetaCyc: PWY-3781;MetaCyc: PWY-4302;MetaCyc: PWY-6692;Reactome: R-HSA-611105;MetaCyc: PWY-5083;KEGG: 00190+7.1.1.2;Reactome: R-HSA-6799198	"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"Fe(II) oxidation";"Respiratory electron transport";"NAD/NADH phosphorylation and dephosphorylation";"Oxidative phosphorylation";"Complex I biogenesis"
XP_053615525.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_053611795.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053615592.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053611643.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053612964.1	22	MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6958;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7726;Reactome: R-HSA-75876;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7592;MetaCyc: PWY-7049;MetaCyc: PWY-7053;MetaCyc: PWY-5353;MetaCyc: PWY-6598;MetaCyc: PWY-7728;MetaCyc: PWY-7725;MetaCyc: PWY-7606;MetaCyc: PWY-7727	"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)"
XP_053599604.1	10	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2197563;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway"
XP_053615964.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053625913.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053607521.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053623343.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_053614410.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_053619024.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_053604087.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053613950.1	8	Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-8953750;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693554	"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Transcriptional Regulation by E2F6";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_053625561.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-1445148	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Intraflagellar transport";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053616908.1	31	MetaCyc: PWY-8012;MetaCyc: PWY-5367;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-7858;MetaCyc: PWY-5147;MetaCyc: PWY-5971;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;MetaCyc: PWY-7664;MetaCyc: PWY-8049;MetaCyc: PWY-7723;MetaCyc: PWY-6519;MetaCyc: PWY-7388;MetaCyc: PWY-5142;MetaCyc: PWY-7663;MetaCyc: PWY-4381;MetaCyc: PWY-6799;MetaCyc: PWY-5989;Reactome: R-HSA-199220;Reactome: R-HSA-75105;MetaCyc: PWY-5973;MetaCyc: PWY-5966-1;MetaCyc: PWY-8047;MetaCyc: PWYG-321;MetaCyc: PWY-5366;MetaCyc: PWY-5994;Reactome: R-HSA-163765;MetaCyc: PWY-7746	"Mupirocin biosynthesis";"Petroselinate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Pederin biosynthesis";"Bacterial bioluminescence";"8-amino-7-oxononanoate biosynthesis I";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Stearate biosynthesis II (bacteria and plants)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bryostatin biosynthesis";"";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Mycobacterial sulfolipid biosynthesis"
XP_053613845.1	2	KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_053604256.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_053618991.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_053604614.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_053607699.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_053608344.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053615058.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053603297.1	6	KEGG: 00680+2.6.1.52;Reactome: R-HSA-977347;KEGG: 00260+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00270+2.6.1.52;KEGG: 00750+2.6.1.52	"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Vitamin B6 metabolism"
XP_053617136.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473	"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint"
XP_053619349.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053619038.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_053608455.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_053620365.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053606099.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053602127.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053621537.1	12	MetaCyc: PWY-7233;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-5873;KEGG: 00130+1.14.99.60;MetaCyc: PWY-7230;MetaCyc: PWY-6708;MetaCyc: PWY-5857;MetaCyc: PWY-5855;MetaCyc: PWY-5870	"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)"
XP_053611941.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053600823.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053601394.1	24	Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"Mitotic Prometaphase";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Kinesins"
XP_053614104.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_053620522.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway"
XP_053612794.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_053615255.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053611524.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053601564.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053624657.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_053614941.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_053621183.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_053620595.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053604394.1	5	Reactome: R-HSA-3656253;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis"
XP_053602507.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012	"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053610519.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_053601256.1	18	KEGG: 00220+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-5913;KEGG: 00400+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6643;MetaCyc: PWY-7115;KEGG: 00401+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00710+2.6.1.1	"Arginine biosynthesis";"Sulfolactate degradation III";"Partial TCA cycle (obligate autotrophs)";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine and proline metabolism";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Cysteine and methionine metabolism";"(R)-cysteate degradation";"Alanine, aspartate and glutamate metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Novobiocin biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms"
XP_053600857.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_053621742.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053608771.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053611756.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes"
XP_053600244.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053620668.1	3	Reactome: R-HSA-70268;MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5	"Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_053604089.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053606733.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053603124.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_053600653.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053607407.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053620226.1	7	MetaCyc: PWY-7807;MetaCyc: PWY-7805;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.7;MetaCyc: PWY-6610;MetaCyc: PWY-6605	"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Purine salvage";"Neutrophil degranulation";"Purine metabolism";"Adenine salvage";"Adenine and adenosine salvage II"
XP_053606805.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053605689.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824	"Betanidin degradation";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis"
XP_053618158.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053603320.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_053613360.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053617333.1	4	MetaCyc: PWY-5737;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922	"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_053605372.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053609589.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-389661;Reactome: R-HSA-77289	"Complex I biogenesis";"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation"
XP_053606097.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053615200.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA"
XP_053613480.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053613373.1	5	Reactome: R-HSA-197264;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-6798695	"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation"
XP_053619347.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053607178.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_053602129.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_053619119.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053620518.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053624853.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053620955.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_053605755.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_053623798.1	5	MetaCyc: PWY-7082;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-6692;KEGG: 00190+7.1.1.8	"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Oxidative phosphorylation"
XP_053609336.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_053604552.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053608400.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_053611355.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_053611828.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_053612575.1	179	Reactome: R-HSA-156827;Reactome: R-HSA-8856828;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-72689;Reactome: R-HSA-917937;Reactome: R-HSA-4608870;Reactome: R-HSA-532668;Reactome: R-HSA-1169408;Reactome: R-HSA-179409;Reactome: R-HSA-174113;Reactome: R-HSA-936440;Reactome: R-HSA-8856825;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-3785653;Reactome: R-HSA-9010553;Reactome: R-HSA-5689877;Reactome: R-HSA-168927;Reactome: R-HSA-2691232;Reactome: R-HSA-9014325;Reactome: R-HSA-5693607;Reactome: R-HSA-936964;Reactome: R-HSA-1236382;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-975110;Reactome: R-HSA-69601;Reactome: R-HSA-201681;Reactome: R-HSA-8863795;Reactome: R-HSA-174048;Reactome: R-HSA-5689901;Reactome: R-HSA-901032;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-5656169;Reactome: R-HSA-9646399;Reactome: R-HSA-975957;Reactome: R-HSA-5675482;Reactome: R-HSA-205043;Reactome: R-HSA-174178;Reactome: R-HSA-2559580;Reactome: R-HSA-917729;Reactome: R-HSA-5654733;Reactome: R-HSA-68827;Reactome: R-HSA-1295596;Reactome: R-HSA-400253;Reactome: R-HSA-975956;Reactome: R-HSA-450302;Reactome: R-HSA-975144;Reactome: R-HSA-174084;Reactome: R-HSA-5357905;Reactome: R-HSA-187577;Reactome: R-HSA-162588;Reactome: R-HSA-8876493;Reactome: R-HSA-6781823;Reactome: R-HSA-4641263;Reactome: R-HSA-6782135;Reactome: R-HSA-1799339;Reactome: R-HSA-5358346;Reactome: R-HSA-6804760;Reactome: R-HSA-937072;Reactome: R-HSA-450321;Reactome: R-HSA-5205685;Reactome: R-HSA-110314;Reactome: R-HSA-174490;Reactome: R-HSA-5655862;Reactome: R-HSA-5689880;Reactome: R-HSA-9637628;Reactome: R-HSA-977225;Reactome: R-HSA-2672351;Reactome: R-HSA-175474;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-2565942;Reactome: R-HSA-5696400;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-9636383;Reactome: R-HSA-983168;Reactome: R-HSA-5685942;Reactome: R-HSA-1234176;Reactome: R-HSA-2894862;Reactome: R-HSA-1358803;Reactome: R-HSA-8951664;Reactome: R-HSA-182971;Reactome: R-HSA-2408557;Reactome: R-HSA-209560;Reactome: R-HSA-5678895;Reactome: R-HSA-8866652;Reactome: R-HSA-2173795;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-2122948;Reactome: R-HSA-6781827;Reactome: R-HSA-5693565;Reactome: R-HSA-6783310;Reactome: R-HSA-9013973;Reactome: R-HSA-9615710;Reactome: R-HSA-3134975;Reactome: R-HSA-69541;Reactome: R-HSA-5654732;Reactome: R-HSA-2173791;Reactome: R-HSA-2644606;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-9013507;Reactome: R-HSA-9020702;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-2173788;Reactome: R-HSA-8948747;Reactome: R-HSA-6782210;Reactome: R-HSA-2979096;Reactome: R-HSA-912631;Reactome: R-HSA-5687128;Reactome: R-HSA-72706;Reactome: R-HSA-2559585;Reactome: R-HSA-4641257;Reactome: R-HSA-5654726;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-110320;Reactome: R-HSA-5654727;Reactome: R-HSA-211733;Reactome: R-HSA-937039;Reactome: R-HSA-8852276;Reactome: R-HSA-5675221;Reactome: R-HSA-209543;Reactome: R-HSA-2871837;Reactome: R-HSA-168928;Reactome: R-HSA-202424;Reactome: R-HSA-3322077;Reactome: R-HSA-5689896;Reactome: R-HSA-8875360;Reactome: R-HSA-2122947;Reactome: R-HSA-68949;Reactome: R-HSA-69231;Reactome: R-HSA-975163;Reactome: R-HSA-6791226;Reactome: R-HSA-5632684;Reactome: R-HSA-168638;Reactome: R-HSA-5696394;Reactome: R-HSA-9033241;Reactome: R-HSA-2173796;Reactome: R-HSA-937042;Reactome: R-HSA-5696395;Reactome: R-HSA-8866654;Reactome: R-HSA-5357956;Reactome: R-HSA-8849469;Reactome: R-HSA-5656121;Reactome: R-HSA-3769402;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-9613829;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-1253288;Reactome: R-HSA-5684264;Reactome: R-HSA-72764;Reactome: R-HSA-2559582;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-6804756;Reactome: R-HSA-6804757;Reactome: R-HSA-9633012;Reactome: R-HSA-937041;Reactome: R-HSA-6807004;Reactome: R-HSA-69481	"L13a-mediated translational silencing of Ceruloplasmin expression";"Clathrin-mediated endocytosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"Formation of a pool of free 40S subunits";"Iron uptake and transport";"Asymmetric localization of PCP proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ISG15 antiviral mechanism";"APC-Cdc20 mediated degradation of Nek2A";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulators of DDX58/IFIH1 signaling";"Cargo recognition for clathrin-mediated endocytosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Myoclonic epilepsy of Lafora";"Regulation of expression of SLITs and ROBOs";"Josephin domain DUBs";"TICAM1, RIP1-mediated IKK complex recruitment";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Processing of DNA double-strand break ends";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TCF dependent signaling in response to WNT";"Downregulation of ERBB2 signaling";"APC/C:Cdc20 mediated degradation of Cyclin B";"Metalloprotease DUBs";"ER Quality Control Compartment (ERQC)";"Peptide chain elongation";"Viral mRNA Translation";"Termination of translesion DNA synthesis";"Aggrephagy";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of necroptotic cell death";"NRIF signals cell death from the nucleus";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxidative Stress Induced Senescence";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Negative regulation of FGFR4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Spry regulation of FGF signaling";"Circadian Clock";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"activated TAK1 mediates p38 MAPK activation";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of TNFR1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Budding and maturation of HIV virion";"InlA-mediated entry of Listeria monocytogenes into host cells";"Formation of TC-NER Pre-Incision Complex";"Regulation of FZD by ubiquitination";"Dual incision in TC-NER";"SRP-dependent cotranslational protein targeting to membrane";"Hedgehog ligand biogenesis";"Regulation of TP53 Activity through Methylation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Pink/Parkin Mediated Mitophagy";"Recognition of DNA damage by PCNA-containing replication complex";"Membrane binding and targetting of GAG proteins";"Translesion synthesis by POLK";"Ub-specific processing proteases";"Modulation by Mtb of host immune system";"Amyloid fiber formation";"Stimuli-sensing channels";"Assembly Of The HIV Virion";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of PLK1 Activity at G2/M Transition";"Dual Incision in GG-NER";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"Prevention of phagosomal-lysosomal fusion";"Antigen processing: Ubiquitination & Proteasome degradation";"HDR through Homologous Recombination (HRR)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Downregulation of ERBB2:ERBB3 signaling";"Neddylation";"EGFR downregulation";"Selenocysteine synthesis";"NF-kB is activated and signals survival";"Defective CFTR causes cystic fibrosis";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Activated NOTCH1 Transmits Signal to the Nucleus";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Fanconi Anemia Pathway";"TICAM1-dependent activation of IRF3/IRF7";"Late endosomal microautophagy";"Regulation of innate immune responses to cytosolic DNA";"Stabilization of p53";"Negative regulation of FGFR3 signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Separation of Sister Chromatids";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Interleukin-1 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"Downregulation of TGF-beta receptor signaling";"Regulation of PTEN localization";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulation of signaling by CBL";"MAPK6/MAPK4 signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Oncogene Induced Senescence";"Degradation of AXIN";"Negative regulation of FGFR1 signaling";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Translesion Synthesis by POLH";"Negative regulation of FGFR2 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"IRAK1 recruits IKK complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of MAPK pathway";"p75NTR recruits signalling complexes";"FCERI mediated NF-kB activation";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Downstream TCR signaling";"Glycogen synthesis";"Ovarian tumor domain proteases";"InlB-mediated entry of Listeria monocytogenes into host cell";"NOTCH1 Intracellular Domain Regulates Transcription";"Orc1 removal from chromatin";"Cyclin D associated events in G1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Hedgehog 'on' state";"NOD1/2 Signaling Pathway";"DNA Damage Recognition in GG-NER";"Peroxisomal protein import";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"IRAK2 mediated activation of TAK1 complex";"Formation of Incision Complex in GG-NER";"E3 ubiquitin ligases ubiquitinate target proteins";"TNFR1-induced NFkappaB signaling pathway";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Translesion synthesis by POLI";"Deactivation of the beta-catenin transactivating complex";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Chaperone Mediated Autophagy";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Downregulation of ERBB4 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Eukaryotic Translation Termination";"Senescence-Associated Secretory Phenotype (SASP)";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"UCH proteinases";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Regulation of TP53 Activity through Phosphorylation";"Regulation of TP53 Degradation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"IKK complex recruitment mediated by RIP1";"Negative regulation of MET activity";"G2/M Checkpoints"
XP_053601868.1	9	Reactome: R-HSA-3656253;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1"
XP_053607149.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_053625425.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053624002.1	10	KEGG: 00562+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 04151+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 05170+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04150+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 05163+2.7.1.153;Reactome: R-HSA-1660499	"Inositol phosphate metabolism";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"PI3K-Akt signaling pathway";"Phosphatidylinositol signaling system";"Human immunodeficiency virus 1 infection";"3-phosphoinositide biosynthesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Synthesis of PIPs at the plasma membrane"
XP_053624539.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053602509.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_053620774.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_053601089.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_053599745.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_053610710.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_053609499.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053621466.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_053618631.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053607939.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053601576.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-418594	"PKA activation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events"
XP_053608053.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053605356.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170;Reactome: R-HSA-216083	"ECM proteoglycans";"Molecules associated with elastic fibres";"Syndecan interactions";"Integrin cell surface interactions"
XP_053616848.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053611444.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053600859.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_053603979.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053622154.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053602235.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_053620479.1	11	Reactome: R-HSA-6782135;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-5651801;Reactome: R-HSA-174430;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400	"Dual incision in TC-NER";"Activation of the pre-replicative complex";"DNA replication initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand synthesis initiation";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER"
XP_053618799.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_053625588.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_053612943.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053601624.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053614007.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053624819.1	12	Reactome: R-HSA-156827;Reactome: R-HSA-72662;Reactome: R-HSA-166208;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-429947;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"mTORC1-mediated signalling";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation"
XP_053599967.1	4	Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522	"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_053621646.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053612497.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053615916.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053608821.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_053617489.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053616729.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053606769.1	3	Reactome: R-HSA-264870;Reactome: R-HSA-6794361;Reactome: R-HSA-6798695	"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins";"Neutrophil degranulation"
XP_053610529.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053601380.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053611749.1	10	MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;Reactome: R-HSA-196757;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-3841;MetaCyc: PWY-5497;MetaCyc: PWY-6613	"Folate transformations I";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate"
XP_053623887.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053619700.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_053624393.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_053601915.1	7	Reactome: R-HSA-381070;Reactome: R-HSA-983170;Reactome: R-HSA-381042;Reactome: R-HSA-381183;Reactome: R-HSA-3371453;Reactome: R-HSA-381033;Reactome: R-HSA-114608	"IRE1alpha activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation"
XP_053617369.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053607329.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053607290.1	8	Reactome: R-HSA-8948747;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210	"Regulation of PTEN localization";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_053611236.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_053606644.1	1	Reactome: R-HSA-1614603	"Cysteine formation from homocysteine"
XP_053617204.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_053611514.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_053621563.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053622621.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_053614749.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-6814122	"PLC beta mediated events";"G alpha (i) signalling events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053601151.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_053600813.1	4	Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I"
XP_053615587.1	5	Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-111469;Reactome: R-HSA-111457;Reactome: R-HSA-9627069	"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC, XIAP-regulated apoptotic response";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity"
XP_053612780.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_053602349.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_053605038.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053611778.1	2	Reactome: R-HSA-442982;Reactome: R-HSA-5673001	"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade"
XP_053614236.1	8	Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-442720	"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"DARPP-32 events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"CREB1 phosphorylation through the activation of Adenylate Cyclase"
XP_053616432.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_053619687.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053600175.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053604624.1	6	MetaCyc: PWY-7165;KEGG: 00053+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530	"L-ascorbate biosynthesis VI (engineered pathway)";"Ascorbate and aldarate metabolism";"Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"Sorbitol biosynthesis II"
XP_053618435.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_053602896.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_053626065.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053619471.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053624570.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053624777.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163615	"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation"
XP_053621819.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_053599686.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_053624646.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_053603344.1	17	MetaCyc: PWY-1622;MetaCyc: PWY-5392;MetaCyc: PWY-8086;MetaCyc: PWY-6969;KEGG: 00270+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-5913;KEGG: 00630+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-561;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115	"Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Cysteine and methionine metabolism";"Methane metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_053622013.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053602024.1	5	KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749	"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_053616842.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053615064.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_053605675.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053623503.1	4	Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination"
XP_053619883.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053614009.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053608504.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053615052.1	6	MetaCyc: PWY-5744;MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-4381;MetaCyc: PWY-6722;MetaCyc: PWY-5789	"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_053617671.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_053610527.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_053617487.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_053625960.1	9	Reactome: R-HSA-69231;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-2173796	"Cyclin D associated events in G1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_053604075.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053606458.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053623157.1	7	MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11	"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system"
XP_053620108.1	33	Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-427413;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-69273;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-6781823;Reactome: R-HSA-69656;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-69231;Reactome: R-HSA-73863;Reactome: R-HSA-8939236;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-69202;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"NoRC negatively regulates rRNA expression";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Cyclin A/B1/B2 associated events during G2/M transition";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Cyclin A:Cdk2-associated events at S phase entry";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"Cyclin D associated events in G1";"RNA Polymerase I Transcription Termination";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_053604881.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972	"Regulation of PTEN gene transcription";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_053623889.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053606610.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053602280.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_053619032.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_053622706.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_053603400.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_053622973.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053600773.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_053601854.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_053607327.1	4	Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903	"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Receptor Mediated Mitophagy"
XP_053617367.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053604249.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053613494.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053618033.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053611676.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053611818.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579	"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange"
XP_053602119.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053601881.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_053614540.1	5	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1679131	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Neutrophil degranulation";"MHC class II antigen presentation";"Trafficking and processing of endosomal TLR"
XP_053604278.1	10	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-437239;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"mTOR signaling pathway";"Relaxin signaling pathway";"RSK activation";"Recycling pathway of L1";"PI3K-Akt signaling pathway"
XP_053623683.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053620528.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_053601249.1	10	KEGG: 00010+2.7.2.3;MetaCyc: PWY-5484;MetaCyc: PWY-6901;Reactome: R-HSA-70263;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-6886;KEGG: 00710+2.7.2.3;MetaCyc: PWY-8004;MetaCyc: PWY-1042	"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)"
XP_053610633.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_053620216.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_053607731.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053620534.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_053619040.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_053624779.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_053603310.1	15	MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-7383;MetaCyc: PWY-2221;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6886;Reactome: R-HSA-70171;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-6142	"Rubisco shunt";"Pyruvate metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Purine metabolism";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_053625305.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053611652.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053607886.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_053613158.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053601075.1	5	Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604	"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling"
XP_053612803.1	6	Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-5620922	"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_053618164.1	10	MetaCyc: PWY-7328;Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6317;MetaCyc: PWY-6397;MetaCyc: PWY-3821;MetaCyc: PWY-6527	"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose detoxification";"Stachyose degradation"
XP_053610202.1	5	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_053600174.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053604625.1	6	MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221	"Sorbitol biosynthesis II";"Caprolactam degradation";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_053618434.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160	"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions"
XP_053626064.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053613093.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053611641.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053614283.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053608630.1	5	MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68;KEGG: 00533+2.4.1.68;KEGG: 00513+2.4.1.68;Reactome: R-HSA-975578	"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_053625432.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053603345.1	17	KEGG: 00630+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-7115;KEGG: 00710+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-1622;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00270+1.1.1.37	"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism"
XP_053616181.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053609396.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053608388.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade"
XP_053602987.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053611026.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053599633.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053605987.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_053617646.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053621231.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053620787.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_053608468.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins"
XP_053623307.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_053620825.1	4	Reactome: R-HSA-428540;Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-186763	"Activation of RAC1";"Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Downstream signal transduction"
XP_053618691.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_053618428.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_053617613.1	4	KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183	"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_053613530.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053616498.1	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
XP_053613418.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_053613737.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053601312.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_053610323.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053615712.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053609643.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053619218.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_053626133.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_053621923.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_053607557.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-165159	"Amino acids regulate mTORC1";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling"
XP_053610091.1	2	Reactome: R-HSA-432722;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis"
XP_053606793.1	3	KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695	"Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation"
XP_053618763.1	13	Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-114508;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-381676;Reactome: R-HSA-2871809	"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Effects of PIP2 hydrolysis";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization"
XP_053606645.1	3	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053611958.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053611515.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053603746.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053617205.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_053606118.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053622155.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053618770.1	13	Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-139853;Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-114508	"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Effects of PIP2 hydrolysis"
XP_053607103.1	9	KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52	"Other glycan degradation";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation"
XP_053614641.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053609566.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053619526.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053610788.1	29	Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-427413;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-167160;Reactome: R-HSA-5696400;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-72086	"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"NoRC negatively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping"
XP_053600030.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053612186.1	12	Reactome: R-HSA-399719;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;Reactome: R-HSA-447038	"Trafficking of AMPA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"NrCAM interactions"
XP_053613542.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_053618810.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism"
XP_053603115.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_053608192.1	16	Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-69473;Reactome: R-HSA-5693571	"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HATs acetylate histones";"Estrogen-dependent gene expression";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)"
XP_053620535.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053606379.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053624597.1	14	MetaCyc: PWY-6969;MetaCyc: PWY-4302;KEGG: 00190+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-7279;MetaCyc: PWY-6728;Reactome: R-HSA-611105;KEGG: 00650+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-7254	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"Citric acid cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle";"Respiratory electron transport";"Butanoate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)"
XP_053608270.1	6	Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16	"Triglyceride catabolism";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation"
XP_053606122.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053614488.1	4	MetaCyc: PWY-5189;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_053609193.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins"
XP_053618165.1	10	Reactome: R-HSA-70370;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6397	"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"
XP_053622331.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053620789.1	9	MetaCyc: PWY-5664;MetaCyc: PWY-7852;MetaCyc: PWY-6983;MetaCyc: PWY-6703;MetaCyc: PWY-5663;MetaCyc: PWY-6147;KEGG: 00790+3.5.4.16;Reactome: R-HSA-1474151;MetaCyc: PWY-7442	"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Threo-tetrahydrobiopterin biosynthesis";"Preq0 biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis"
XP_053608263.1	9	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_053602989.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_053625753.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_053623309.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_053613246.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_053614368.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_053607416.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053614191.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_053626076.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_053616293.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053605768.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053610126.1	6	MetaCyc: PWY-622;Reactome: R-HSA-189085;MetaCyc: PWY-5067;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1	"Starch biosynthesis";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch and sucrose metabolism"
XP_053615701.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_053612728.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053612463.1	8	Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation"
XP_053624671.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053601301.1	5	MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis"
XP_053607559.1	8	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-3371571	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"HSF1-dependent transactivation"
XP_053601855.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053601328.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053603462.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_053623572.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_053613605.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_053611191.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_053613495.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053618412.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053622071.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053626052.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053605674.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_053604411.1	3	Reactome: R-HSA-9634638;Reactome: R-HSA-525793;Reactome: R-HSA-5663220	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis";"RHO GTPases Activate Formins"
XP_053602674.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053618904.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053625520.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053606920.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_053616960.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_053610967.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053618086.1	10	Reactome: R-HSA-156827;Reactome: R-HSA-381042;Reactome: R-HSA-72706;Reactome: R-HSA-72731;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-9648895;Reactome: R-HSA-72695;Reactome: R-HSA-382556	"L13a-mediated translational silencing of Ceruloplasmin expression";"PERK regulates gene expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Recycling of eIF2:GDP";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Response of EIF2AK1 (HRI) to heme deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"ABC-family proteins mediated transport"
XP_053615856.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053615383.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053604074.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053610211.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053617657.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_053606944.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_053625544.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053610403.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053607088.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_053608198.1	16	Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-201722;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586	"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"HATs acetylate histones";"Estrogen-dependent gene expression";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Formation of the beta-catenin:TCF transactivating complex";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence"
XP_053619543.1	14	Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167152	"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_053600282.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2206296;Reactome: R-HSA-2024096	"CS/DS degradation";"MPS II - Hunter syndrome";"HS-GAG degradation"
XP_053616391.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053602526.1	7	Reactome: R-HSA-5696395;Reactome: R-HSA-110362;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-5685939;Reactome: R-HSA-2173795;Reactome: R-HSA-3108214	"Formation of Incision Complex in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"HDR through MMEJ (alt-NHEJ)";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"SUMOylation of DNA damage response and repair proteins"
XP_053610745.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053605526.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053619234.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_053604203.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565	"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053600919.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_053608481.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_053611880.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053619666.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_053608239.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_053616286.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053601565.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_053615254.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_053612795.1	11	KEGG: 00230+1.17.1.4;Reactome: R-HSA-74259;MetaCyc: PWY-5497;MetaCyc: PWY-6607;MetaCyc: PWY-6538;MetaCyc: PWY-6608;MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-6999;Reactome: R-HSA-8851680;MetaCyc: PWY-6606	"Purine metabolism";"Purine catabolism";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation I";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Theophylline degradation";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation II"
XP_053601148.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_053607869.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053615878.1	8	Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68827	"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex"
XP_053615616.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053614016.1	6	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5693565;Reactome: R-HSA-8939211;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ESR-mediated signaling";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation"
XP_053606330.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_053615643.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053610050.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-4570571	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)"
XP_053606688.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053609712.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_053601924.1	10	Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-8939243;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695;Reactome: R-HSA-201688;Reactome: R-HSA-2514853	"Synthesis of PC";"Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"Regulation of PTEN stability and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes"
XP_053614880.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053615281.1	3	KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403	"Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling"
XP_053601541.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_053611362.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_053601322.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053620160.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_053610313.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053608454.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_053620364.1	19	Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-3000484;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038	"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"Chylomicron assembly";"Cell surface interactions at the vascular wall";"VLDL clearance";"Clathrin-mediated endocytosis";"VLDL assembly";"Chylomicron remodeling";"Platelet sensitization by LDL";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"Scavenging by Class F Receptors";"LDL remodeling";"Regulation of TLR by endogenous ligand";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"LDL clearance"
XP_053604148.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_053615849.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053599986.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053618418.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_053618650.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053618093.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053619025.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053615396.1	15	Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569	"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_053607546.1	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_053611482.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053603388.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-428930	"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor"
XP_053604615.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_053622921.1	12	MetaCyc: PWY-6978;KEGG: 00130+2.5.1.39;Reactome: R-HSA-1268020;MetaCyc: PWY-6708;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-5873;MetaCyc: PWY-5856;MetaCyc: PWY-5870	"Plastoquinol-9 biosynthesis II";"Ubiquinone and other terpenoid-quinone biosynthesis";"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)"
XP_053600708.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-5083630;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399;Reactome: R-HSA-1912408	"Notch-HLH transcription pathway";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Transcription and Translation"
XP_053608345.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053607513.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape"
XP_053603630.1	3	KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581;MetaCyc: PWY-5963	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis"
XP_053606521.1	5	Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;MetaCyc: PWY-7511	"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Protein ubiquitination"
XP_053614296.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_053611835.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72649	"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation"
XP_053617659.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_053611703.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053624073.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053610221.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_053599744.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_053600261.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053609470.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_053602098.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_053610208.1	13	Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_053608382.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053621333.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_053606385.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-164378	"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling"
XP_053614461.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_053625717.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_053600917.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_053613141.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_053625438.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_053621751.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053618422.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_053608462.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053620352.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_053625660.1	29	Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693554;Reactome: R-HSA-6803204;Reactome: R-HSA-5693607;Reactome: R-HSA-3371453;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-6804760;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5685942;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-6803207;Reactome: R-HSA-5693568;Reactome: R-HSA-6804757;Reactome: R-HSA-349425;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-912446;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69541	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Processing of DNA double-strand break ends";"Regulation of HSF1-mediated heat shock response";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Activity through Methylation";"Relaxin signaling pathway";"HDR through Homologous Recombination (HRR)";"mTOR signaling pathway";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"Thermogenesis";"Human papillomavirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic recombination";"PI3K-Akt signaling pathway";"Stabilization of p53"
XP_053612574.1	7	Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;Reactome: R-HSA-8856828;KEGG: 04070+3.1.3.36	"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Clathrin-mediated endocytosis";"Phosphatidylinositol signaling system"
XP_053611354.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_053607867.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_053599669.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053608237.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_053625424.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053602781.1	6	Reactome: R-HSA-9022537;Reactome: R-HSA-9022692;Reactome: R-HSA-9609690;Reactome: R-HSA-1989781;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569	"Loss of MECP2 binding ability to the NCoR/SMRT complex";"Regulation of MECP2 expression and activity";"HCMV Early Events";"PPARA activates gene expression";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_053600048.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_053624806.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_053602413.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053619423.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053601318.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053620775.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053609701.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_053619212.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_053603263.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053606441.1	17	Reactome: R-HSA-174414;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-174417;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-174437;Reactome: R-HSA-5696397;Reactome: R-HSA-69183;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801	"Processive synthesis on the C-strand of the telomere";"Polymerase switching";"Removal of the Flap Intermediate";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the lagging strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair"
XP_053610116.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053611952.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053615847.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053617466.1	2	Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_053602295.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053605754.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_053620954.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_053614976.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053612193.1	8	Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8	"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism"
XP_053603192.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_053616890.1	5	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670;Reactome: R-HSA-4085001	"Glycosphingolipid metabolism";"Neutrophil degranulation";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis";"Sialic acid metabolism"
XP_053606112.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053613810.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
XP_053621073.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053607230.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1679131;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Neutrophil degranulation";"MHC class II antigen presentation";"Trafficking and processing of endosomal TLR";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_053620376.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_053603125.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_053618820.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_053613302.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053608006.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053625879.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053613231.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_053619865.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_053608893.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_053620849.1	5	Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-6798695	"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Neutrophil degranulation"
XP_053623026.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053615815.1	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_053612209.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779	"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_053609787.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053619314.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053620281.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_053603044.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053621737.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053601197.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053621650.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053615364.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053623894.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053605324.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_053607811.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053616863.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
XP_053602324.1	7	KEGG: 00330+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.22	"Arginine and proline metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Glutathione metabolism"
XP_053606823.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_053612173.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_053604080.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053614417.1	17	Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053607132.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_053621093.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism"
XP_053610908.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_053625761.1	11	MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7790;MetaCyc: PWY-5154;KEGG: 00240+2.1.3.2;KEGG: 00250+2.1.3.2;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7400;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7791	"UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis II";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis III"
XP_053612484.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_053613204.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053600961.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7587	"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)"
XP_053605338.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053608147.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-418594	"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN";"G alpha (i) signalling events"
XP_053625899.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_053606210.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones"
XP_053624308.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053624542.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053623665.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053615451.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053611996.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053611417.1	11	Reactome: R-HSA-168138;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660517;Reactome: R-HSA-5668599;Reactome: R-HSA-1660514;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.137;Reactome: R-HSA-109704;Reactome: R-HSA-1632852	"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the late endosome membrane";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"PI3K Cascade";"Macroautophagy"
XP_053600945.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_053614276.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing"
XP_053609490.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053605078.1	6	Reactome: R-HSA-9615017;Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism"
XP_053625693.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901	"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs"
XP_053610544.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_053625403.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053607930.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053606189.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_053621308.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053615962.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053615594.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053620643.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_053622050.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_053617991.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053619912.1	4	MetaCyc: PWY-8072;MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040	"Alanine racemization";"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Ansatrienin biosynthesis"
XP_053603963.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226	"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053612594.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053613923.1	10	Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-9018519;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-76042	"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_053624530.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling"
XP_053624650.1	2	Reactome: R-HSA-5693554;Reactome: R-HSA-2564830	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly"
XP_053624418.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_053618913.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053602995.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053602707.1	14	Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7782	"Synthesis of PA";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Plasmalogen biosynthesis"
XP_053605707.1	5	Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
XP_053620616.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053603156.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053620847.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation"
XP_053601752.1	9	Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-69205	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Polymerase switching";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"G1/S-Specific Transcription"
XP_053622005.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_053612207.1	13	KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52	"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosphingolipid metabolism";"Other glycan degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism"
XP_053600097.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-2173789	"Cargo recognition for clathrin-mediated endocytosis";"UCH proteinases";"Neddylation";"Iron uptake and transport";"TGF-beta receptor signaling activates SMADs"
XP_053619340.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_053620262.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_053601199.1	12	Reactome: R-HSA-71240;MetaCyc: PWY-6309;KEGG: 00270+4.4.1.13;MetaCyc: PWY-601;MetaCyc: PWY-6936;KEGG: 00380+2.6.1.7;MetaCyc: PWY-801;KEGG: 00450+4.4.1.13;MetaCyc: PWY-7901;MetaCyc: PWY-2821;MetaCyc: PWY-6842;MetaCyc: PWY-1187	"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tryptophan";"Seleno-amino acid biosynthesis (plants)";"Tryptophan metabolism";"Homocysteine and cysteine interconversion";"Selenocompound metabolism";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from homomethionine"
XP_053624605.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053621739.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_053619928.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_053622116.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_053618806.1	14	Reactome: R-HSA-75109;Reactome: R-HSA-1483191;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-8052;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483213;Reactome: R-HSA-4419969;KEGG: 00600+3.1.3.4	"Triglyceride biosynthesis";"Synthesis of PC";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Ether lipid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE";"Depolymerisation of the Nuclear Lamina";"Sphingolipid metabolism"
XP_053611264.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053605635.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_053599611.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_053602635.1	3	MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3	"Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism"
XP_053608317.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053617494.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_053611556.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_053606244.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex"
XP_053625782.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_053602047.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_053620193.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053608149.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-418594	"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN";"G alpha (i) signalling events"
XP_053622933.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-6824	"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Justicidin B biosynthesis"
XP_053621585.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053625933.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_053616031.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
YP_009166943.1	7	Reactome: R-HSA-611105;MetaCyc: PWY-6692;MetaCyc: PWY-4302;MetaCyc: PWY-3781;Reactome: R-HSA-6799198;KEGG: 00190+7.1.1.2;MetaCyc: PWY-5083	"Respiratory electron transport";"Fe(II) oxidation";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration I (cytochrome c)";"Complex I biogenesis";"Oxidative phosphorylation";"NAD/NADH phosphorylation and dephosphorylation"
XP_053606533.1	8	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_053613367.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053614556.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053616371.1	5	KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22	"Sphingolipid metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism"
XP_053607027.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053610438.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_053616517.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053603704.1	3	MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_053624820.1	12	Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-156827	"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Translation initiation complex formation";"Deadenylation of mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053625221.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053622221.1	8	Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025	"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation"
XP_053612981.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053626083.1	4	MetaCyc: PWY-6829;MetaCyc: PWY-7285;Reactome: R-HSA-6782315;MetaCyc: PWY-7286	"Trna methylation (yeast)";"Methylwyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_053615981.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_053608407.1	6	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"Ion channel transport";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_053615775.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_053621422.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_053607985.1	6	Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis"
XP_053616667.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053607114.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053610660.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;MetaCyc: PWY-7221	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053611572.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_053604375.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_053603886.1	4	MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway"
XP_053604224.1	6	MetaCyc: PWY-7356;MetaCyc: PWY-6908;MetaCyc: PWY-6907;MetaCyc: PWY-6898;Reactome: R-HSA-196819;KEGG: 00730+2.7.6.2	"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III";"Vitamin B1 (thiamin) metabolism";"Thiamine metabolism"
XP_053599973.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053617845.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053619995.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724	"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription"
XP_053602289.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_053624691.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_053605289.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053624401.1	13	MetaCyc: PWY-7857;KEGG: 00720+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-5133;MetaCyc: PWY-6672;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7118;Reactome: R-HSA-71384;KEGG: 00680+6.2.1.1	"Adlupulone and adhumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"L-isoleucine biosynthesis V";"Glycolysis / Gluconeogenesis";"Lupulone and humulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Cis-genanyl-coa degradation";"Propanoate metabolism";"Chitin degradation to ethanol";"Ethanol oxidation";"Methane metabolism"
XP_053602431.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_053610440.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_053607297.1	8	MetaCyc: PWY-7717;MetaCyc: PWY-5651;MetaCyc: PWY-7734;MetaCyc: PWY-7733;MetaCyc: PWY-7765;KEGG: 00630+3.5.1.9;MetaCyc: PWY-6309;KEGG: 00380+3.5.1.9	"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Quinoxaline-2-carboxylate biosynthesis";"3-hydroxyquinaldate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Glyoxylate and dicarboxylate metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism"
XP_053605431.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_053613475.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053608156.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053614453.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_053609594.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_053623592.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053611714.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360	"Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_053613913.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8869496	"Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_053622091.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events";"Late endosomal microautophagy"
XP_053625091.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053620186.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053600988.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053625788.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5626467	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs"
XP_053604826.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_053603284.1	9	MetaCyc: PWY-7411;MetaCyc: PWY-6118;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981;MetaCyc: PWY-7902;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.8	"Phosphatidate biosynthesis (yeast)";"Glycerol-3-phosphate shuttle";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Glucosylglycerol biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism"
XP_053605694.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-5469	"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Sesamin biosynthesis"
XP_053602404.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_053624434.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_053614000.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1799339	"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane"
XP_053621311.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053600891.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-3232118;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565	"Processing of DNA double-strand break ends";"SUMOylation of transcription factors";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053613136.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_053599960.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_053615600.1	3	MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_053612490.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_053600769.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_053617176.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053604094.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053616529.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_053606175.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_053610432.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_053618957.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_053624259.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053606399.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053624311.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053624770.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_053616260.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053621434.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053619338.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_053603251.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_053614427.1	2	Reactome: R-HSA-156581;Reactome: R-HSA-72764	"Methylation";"Eukaryotic Translation Termination"
XP_053604467.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053609484.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053601094.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053614549.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053623105.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-381038;Reactome: R-HSA-2565942	"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"XBP1(S) activates chaperone genes";"Regulation of PLK1 Activity at G2/M Transition"
XP_053604387.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053623362.1	7	Reactome: R-HSA-2151201;Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-163210	"Transcriptional activation of mitochondrial biogenesis";"Cristae formation";"Oxidative phosphorylation";"ATP biosynthesis";"Photosynthesis";"Mitochondrial protein import";"Formation of ATP by chemiosmotic coupling"
XP_053619120.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053618231.1	24	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Kinesins"
XP_053607808.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_053604758.1	12	MetaCyc: PWY-5872;MetaCyc: PWY-5873;MetaCyc: PWY-5856;KEGG: 00130+2.1.1.222+2.1.1.64;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-7233;MetaCyc: PWY-5870;MetaCyc: PWY-5855;MetaCyc: PWY-5857;MetaCyc: PWY-7230;MetaCyc: PWY-6708	"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (prokaryotic)"
XP_053601240.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053609209.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053615580.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053612580.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-6598	"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis"
XP_053611578.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_053612358.1	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_053615358.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053617799.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import"
XP_053608044.1	3	Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329	"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine"
XP_053624763.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_053605287.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053626121.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"HCMV Early Events";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_053603407.1	5	Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400	"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Dual Incision in GG-NER"
XP_053602287.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_053601389.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053624223.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_053607299.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_053617360.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
XP_053604536.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053605056.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053610414.1	5	Reactome: R-HSA-3270619;Reactome: R-HSA-3134975;Reactome: R-HSA-1834941;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695	"IRF3-mediated induction of type I IFN";"Regulation of innate immune responses to cytosolic DNA";"STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines";"Neutrophil degranulation"
XP_053609898.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053608353.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053602056.1	7	Reactome: R-HSA-73817;MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6277	"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_053609775.1	10	Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;MetaCyc: PWY-6807;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23	"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)";"HS-GAG degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Other glycan degradation"
XP_053614258.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053610902.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053621257.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053622359.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053611055.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053621904.1	4	Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-9646399;Reactome: R-HSA-3899300	"Chaperone Mediated Autophagy";"Late endosomal microautophagy";"Aggrephagy";"SUMOylation of transcription cofactors"
XP_053625211.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053614732.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053624548.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053624165.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053611429.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_053614983.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_053622967.1	7	Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-110331	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends";"Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged purine"
XP_053621086.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053601672.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053616720.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_053600767.1	14	KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-5981;MetaCyc: PWY-7411	"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)"
XP_053616527.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_053622686.1	6	MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143	"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_053602072.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-202433;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"Generation of second messenger molecules";"RHO GTPases Activate WASPs and WAVEs"
XP_053611732.1	4	Reactome: R-HSA-162699;Reactome: R-HSA-4719377;Reactome: R-HSA-4719360;Reactome: R-HSA-4717374	"Synthesis of dolichyl-phosphate mannose";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)"
XP_053603317.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_053614055.1	5	Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5610787	"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'off' state"
XP_053606397.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053604469.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053612655.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_053615655.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_053610100.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053621548.1	10	Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-400206;Reactome: R-HSA-9022702;Reactome: R-HSA-9022699;Reactome: R-HSA-427413;Reactome: R-HSA-9022692;Reactome: R-HSA-9022538;Reactome: R-HSA-3899300;Reactome: R-HSA-983231	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates transcription of neuronal ligands";"MECP2 regulates neuronal receptors and channels";"NoRC negatively regulates rRNA expression";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to 5mC-DNA";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production"
XP_053624141.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-73779	"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_053604389.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053614740.1	7	Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110331;Reactome: R-HSA-2559586;Reactome: R-HSA-1221632;Reactome: R-HSA-171306	"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged purine";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic synapsis";"Packaging Of Telomere Ends"
XP_053624931.1	11	Reactome: R-HSA-8940973;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8939236;Reactome: R-HSA-69231;Reactome: R-HSA-2029482;Reactome: R-HSA-5693565;Reactome: R-HSA-428890;Reactome: R-HSA-983231;Reactome: R-HSA-5685938	"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"T cell receptor signaling pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"Regulation of actin dynamics for phagocytic cup formation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Role of ABL in ROBO-SLIT signaling";"Factors involved in megakaryocyte development and platelet production";"HDR through Single Strand Annealing (SSA)"
XP_053619635.1	19	MetaCyc: PWY-7226;MetaCyc: PWY-7187;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7221;MetaCyc: PWY-6545;MetaCyc: PWY-7184;Reactome: R-HSA-380270;Reactome: R-HSA-380320;MetaCyc: PWY-7222;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7224;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7210	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_053602901.1	11	Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163359	"PKA activation";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation"
XP_053601536.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_053599621.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053618671.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430	"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling"
XP_053625126.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-168164	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade"
XP_053622126.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053599608.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053616478.1	5	MetaCyc: PWY-5514;MetaCyc: PWY-6855;MetaCyc: PWY-6906;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Glycolysis";"Amino sugar and nucleotide sugar metabolism"
XP_053609207.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_053613806.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053611258.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053620587.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053609102.1	3	MetaCyc: PWY-7999;Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4	"Vitamin K-epoxide cycle";"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_053619274.1	19	Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828;Reactome: R-HSA-8963888;Reactome: R-HSA-202733;Reactome: R-HSA-3000484;Reactome: R-HSA-3000471;Reactome: R-HSA-432142;Reactome: R-HSA-3000497;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938	"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"VLDL assembly";"Chylomicron remodeling";"VLDL clearance";"Clathrin-mediated endocytosis";"Chylomicron assembly";"Cell surface interactions at the vascular wall";"Scavenging by Class F Receptors";"Scavenging by Class B Receptors";"Platelet sensitization by LDL";"Scavenging by Class H Receptors";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"LDL remodeling";"Regulation of TLR by endogenous ligand"
XP_053612096.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053625273.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053605315.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053623300.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_053613537.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_053613730.1	5	Reactome: R-HSA-4341670;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-2132295	"Defective NEU1 causes sialidosis";"Sialic acid metabolism";"Neutrophil degranulation";"Glycosphingolipid metabolism";"MHC class II antigen presentation"
XP_053600661.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053606363.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_053608103.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_053617311.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053608045.1	2	KEGG: 00500+3.2.1.26;KEGG: 00052+3.2.1.26	"Starch and sucrose metabolism";"Galactose metabolism"
XP_053622109.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053601022.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053611343.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053611062.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053618819.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_053612448.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_053606370.1	24	Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-444257;Reactome: R-HSA-2730905;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-354192;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5625740;KEGG: 04150+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-1257604;Reactome: R-HSA-114604;Reactome: R-HSA-392451;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9634635;KEGG: 05165+2.7.11.1	"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"RSK activation";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"VEGFR2 mediated vascular permeability";"Integrin signaling";"Relaxin signaling pathway";"Regulation of TP53 Degradation";"RHO GTPases activate PKNs";"mTOR signaling pathway";"Activation of AKT2";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"PI3K-Akt signaling pathway";"VEGFR2 mediated cell proliferation";"PIP3 activates AKT signaling";"GPVI-mediated activation cascade";"G beta:gamma signalling through PI3Kgamma";"Thermogenesis";"Estrogen-stimulated signaling through PRKCZ";"Human papillomavirus infection"
XP_053621435.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053615448.1	10	Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-76042	"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_053607723.1	5	MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317	"Stachyose degradation";"D-galactose detoxification";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)"
XP_053600511.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053617763.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053608557.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053612838.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053615838.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053624152.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_053610181.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053613829.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053602716.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7601	"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_053620497.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053602405.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_053620607.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_053600118.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053603285.1	9	KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981;MetaCyc: PWY-7385;MetaCyc: PWY-6118;MetaCyc: PWY-7411;MetaCyc: PWY-7902;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5667	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"Glycerol-3-phosphate shuttle";"Phosphatidate biosynthesis (yeast)";"Glucosylglycerol biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I"
XP_053621799.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_053624435.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
XP_053608248.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053625529.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053600037.1	57	Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-6798695;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-2467813	"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"UCH proteinases";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Neutrophil degranulation";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids"
XP_053617691.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053617428.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_053620943.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_053614316.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_053604095.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053613742.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_053616357.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053615662.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_053619994.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-6804758	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation"
XP_053603513.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-6783310;Reactome: R-HSA-983168	"Protein ubiquitination";"Fanconi Anemia Pathway";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053622993.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_053613474.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053609900.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053609595.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_053611696.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053611715.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis"
XP_053611406.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053620589.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053607990.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053621480.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053613539.1	3	Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329	"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine"
XP_053609518.1	11	Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-383280;Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Nuclear Receptor transcription pathway";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"Circadian Clock";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_053611875.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053602568.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_053611798.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053611936.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053612501.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_053616126.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-6807505;Reactome: R-HSA-983168	"Protein ubiquitination";"RNA polymerase II transcribes snRNA genes";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053612243.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053602876.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053618817.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_053602450.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053599911.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053615243.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053605618.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053605876.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_053617412.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_053624797.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_053619601.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-381038	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes"
XP_053603242.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_053612654.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_053615216.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053612216.1	5	Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400	"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER"
XP_053615534.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_053616686.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053608559.1	9	Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-7039;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-112043	"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events"
XP_053604018.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_053609226.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053613827.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053621360.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053610162.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053600122.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053613971.1	37	Reactome: R-HSA-141444;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-204005;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-2132295;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-9639288;Reactome: R-HSA-983170;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-3232142;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"COPII-mediated vesicle transport";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"MHC class II antigen presentation";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amino acids regulate mTORC1";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of ubiquitinylation proteins";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events"
XP_053618250.1	5	KEGG: 00281+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00280+4.1.3.4;KEGG: 00072+4.1.3.4;KEGG: 00650+4.1.3.4	"Geraniol degradation";"Mevalonate degradation";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Butanoate metabolism"
XP_053599729.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_053613466.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_053621590.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_053625527.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053616967.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_053600920.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_053621797.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867	"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex"
XP_053608416.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053600502.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_053606702.1	11	Reactome: R-HSA-5628897;Reactome: R-HSA-611105;Reactome: R-HSA-111464;Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-3299685;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-1268020;Reactome: R-HSA-111459;Reactome: R-HSA-111458	"TP53 Regulates Metabolic Genes";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"Detoxification of Reactive Oxygen Species";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Mitochondrial protein import";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome"
XP_053608997.1	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_053600348.1	3	Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709	"Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis";"O-linked glycosylation of mucins"
XP_053601603.1	3	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation"
XP_053622839.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053601493.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053602398.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053604809.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053599830.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053624480.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053602161.1	1	Reactome: R-HSA-73621	"Pyrimidine catabolism"
XP_053616506.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053609774.1	10	Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23	"Neutrophil degranulation";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series"
XP_053610415.1	5	Reactome: R-HSA-3249367;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-3134975;Reactome: R-HSA-1834941	"STAT6-mediated induction of chemokines";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Regulation of innate immune responses to cytosolic DNA";"STING mediated induction of host immune responses"
XP_053608082.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_053625449.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_053613853.1	5	Reactome: R-HSA-4085001;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295	"Sialic acid metabolism";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism";"Neutrophil degranulation";"MHC class II antigen presentation"
XP_053625669.1	7	MetaCyc: PWY-7791;KEGG: 00230+3.5.2.5;MetaCyc: PWY-7790;MetaCyc: PWY-5698;MetaCyc: PWY-5697;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5686	"UMP biosynthesis III";"Purine metabolism";"UMP biosynthesis II";"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Allantoin degradation to ureidoglycolate I (urea producing)";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_053622669.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_053622472.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053619182.1	4	Reactome: R-HSA-6807047;Reactome: R-HSA-6807062;MetaCyc: PWY-8026;KEGG: 00100+1.3.1.72	"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis"
XP_053601765.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053625472.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_053615522.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_053604486.1	1	Reactome: R-HSA-977225	"Amyloid fiber formation"
XP_053605562.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053600330.1	2	Reactome: R-HSA-2408508;Reactome: R-HSA-389661	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation"
XP_053602562.1	5	MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661	"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation"
XP_053612341.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_053612522.1	20	MetaCyc: PWY-735;MetaCyc: PWY-7574;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-6920;MetaCyc: PWY-7854;MetaCyc: PWY-7007;Reactome: R-HSA-9033241;MetaCyc: PWY-7291	"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoate metabolism";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)"
XP_053609512.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053603061.1	12	MetaCyc: PWY-6932;MetaCyc: PWY-5340;Reactome: R-HSA-174362;Reactome: R-HSA-2408550;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.7.4	"Selenate reduction";"Sulfate activation for sulfonation";"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfite oxidation III";"Sulfur metabolism";"Selenocompound metabolism";"Purine metabolism";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Monobactam biosynthesis";"Purine metabolism"
XP_053603523.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68949	"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin"
XP_053613021.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053602994.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_053605994.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_053618474.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053623236.1	13	KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6842;Reactome: R-HSA-196836;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;Reactome: R-HSA-156590;MetaCyc: PWY-6370;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7533;MetaCyc: PWY-2261;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18	"Drug metabolism - cytochrome P450";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Vitamin C (ascorbate) metabolism";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Ascorbate recycling (cytosolic)";"Ascorbate and aldarate metabolism";"Gliotoxin biosynthesis";"Ascorbate glutathione cycle";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes"
XP_053607591.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053617530.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_053622744.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_053604366.1	14	KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-7587	"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)"
XP_053623664.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053600944.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_053609479.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_053602612.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053610545.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
XP_053620926.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition"
XP_053600128.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053610168.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_053612766.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-5689880	"Ovarian tumor domain proteases";"Ub-specific processing proteases"
XP_053613646.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053624888.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_053599673.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053606919.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_053624991.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163359	"PKA activation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Hedgehog 'off' state";"G alpha (z) signalling events";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation"
XP_053618623.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053603999.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053611326.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053612485.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_053624271.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053600521.1	8	Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis"
XP_053603637.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_053625456.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_053622870.1	24	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Resolution of Sister Chromatid Cohesion";"Aggrephagy"
XP_053623822.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_053614159.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_053601741.1	18	MetaCyc: PWY-7176;MetaCyc: PWY-7187;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7221;MetaCyc: PWY-7184;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224	"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage"
XP_053602392.1	40	KEGG: 00623+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-6883;MetaCyc: PWY-6863;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7007;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6945;KEGG: 00360+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00903+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-6946;MetaCyc: PWY-7779;KEGG: 00410+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7401;MetaCyc: PWY-7778;MetaCyc: PWY-7216;MetaCyc: PWY-7656;MetaCyc: PWY-5138;MetaCyc: PWY-5789;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-6583;MetaCyc: PWY-1361;MetaCyc: PWY-7654;MetaCyc: PWY-6944;MetaCyc: PWY-5136	"Toluene degradation";"Fatty acid salvage";"Pyruvate fermentation to butanol II (engineered)";"Pyruvate fermentation to hexanol (engineered)";"Caprolactam degradation";"Glutaryl-coa degradation";"Lysine degradation";"Tryptophan metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid elongation";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"Aminobenzoate degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Phenylalanine metabolism";"Butanoate metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Limonene and pinene degradation";"Carbon fixation pathways in prokaryotes";"Benzoate degradation";"Valine, leucine and isoleucine degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Methyl tert-butyl ether degradation";"beta-Alanine metabolism";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"2-methylpropene degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid beta-oxidation IV (unsaturated, even number)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Geraniol degradation";"Fermentation to 2-methylbutanoate";"Pyruvate fermentation to butanol I";"Benzoyl-coa degradation I (aerobic)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Androstenedione degradation";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_053615814.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053603045.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053619315.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053601486.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_053616346.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053623895.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053615365.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053605325.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053612102.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_053618537.1	9	KEGG: 00270+2.6.1.5;KEGG: 00360+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00960+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00400+2.6.1.5	"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Tyrosine catabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Novobiocin biosynthesis";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis"
XP_053615102.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938	"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)"
XP_053602325.1	27	Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-159230	"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA"
XP_053618657.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053601034.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053600465.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_053610425.1	2	Reactome: R-HSA-70263;Reactome: R-HSA-70171	"Gluconeogenesis";"Glycolysis"
XP_053625667.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053617820.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053621494.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_053607984.1	6	KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433;MetaCyc: PWY-7290;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122	"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis"
XP_053611241.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_053612083.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_053607115.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053618386.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_053604374.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_053623818.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053604225.1	6	MetaCyc: PWY-6898;MetaCyc: PWY-6907;MetaCyc: PWY-6908;MetaCyc: PWY-7356;KEGG: 00730+2.7.6.2;Reactome: R-HSA-196819	"Thiamine salvage III";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage IV (yeast)";"Thiamine metabolism";"Vitamin B1 (thiamin) metabolism"
XP_053615442.1	12	KEGG: 00520+2.7.7.9;KEGG: 00561+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-6527;KEGG: 00500+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-3801;Reactome: R-HSA-3322077	"Amino sugar and nucleotide sugar metabolism";"Glycerolipid metabolism";"Formation of the active cofactor, UDP-glucuronate";"Stachyose degradation";"Starch and sucrose metabolism";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Sucrose degradation II (sucrose synthase)";"Glycogen synthesis"
XP_053618466.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_053613779.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226	"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053603443.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_053599544.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_053613250.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_053601001.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053618291.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-168276	"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways"
XP_053621631.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_053607873.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053603705.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-6798695;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Neutrophil degranulation";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_053606496.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_053625371.1	8	MetaCyc: PWY-7400;MetaCyc: PWY-4983;Reactome: R-HSA-70635;MetaCyc: PWY-5;KEGG: 00220+4.3.2.1;MetaCyc: PWY-4984;MetaCyc: PWY-5154;KEGG: 00250+4.3.2.1	"L-arginine biosynthesis IV (archaebacteria)";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"Canavanine biosynthesis";"Arginine biosynthesis";"Urea cycle";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism"
XP_053622710.1	6	KEGG: 00520+2.7.7.12;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12;Reactome: R-HSA-5609978;MetaCyc: PWY-6317;Reactome: R-HSA-70370	"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Galactose metabolism";"Defective GALT can cause Galactosemia";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism"
XP_053611123.1	3	KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5	"Styrene degradation";"Tyrosine catabolism";"Tyrosine metabolism"
XP_053614503.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_053600112.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053616897.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_053610890.1	58	Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-5689901;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-69481	"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neutrophil degranulation";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Metalloprotease DUBs";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints"
XP_053609216.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053599921.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_053605628.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053601956.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053618827.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_053610582.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053609243.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053618785.1	14	Reactome: R-HSA-75109;MetaCyc: PWY-8055;Reactome: R-HSA-1483191;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8052;MetaCyc: PWY-8053;MetaCyc: PWY-7782;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;MetaCyc: PWY-8051;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;KEGG: 00600+3.1.3.4	"Triglyceride biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PC";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Sphingolipid metabolism"
XP_053624551.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053600804.1	27	Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-6784531	"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"snRNP Assembly";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus"
XP_053614157.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_053611683.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053622004.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053616116.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053612430.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053612518.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053615955.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053625004.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_053624494.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053615840.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053611265.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053620200.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053625986.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053605634.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_053602634.1	3	Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857	"Digestion of dietary lipid";"Glycerolipid metabolism";"Retinol biosynthesis"
XP_053622986.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_053624382.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_053613327.1	17	Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-141430	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex"
XP_053611238.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_053600879.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_053624951.1	11	MetaCyc: PWY-6963;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2;Reactome: R-HSA-210455;Reactome: R-HSA-8964539;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-5675;MetaCyc: PWY-381;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2	"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"L-glutamine biosynthesis III";"Nitrate reduction V (assimilatory)";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism"
XP_053601636.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053621115.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053607604.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053625079.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_053621648.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053606004.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_053609928.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_053604572.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_053609901.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053611199.1	4	KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817	"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_053620222.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_053607631.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_053603487.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_053610097.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053606986.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053617053.1	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_053601309.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_053605207.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053620295.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012	"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053624237.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053623142.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053624679.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053614224.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_053604264.1	4	KEGG: 00790+4.1.99.22;KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_053617310.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053614199.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053600660.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053601572.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053616627.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_053606667.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053617985.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053602898.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053623301.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_053624873.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_053599688.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_053621679.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053607158.1	17	Reactome: R-HSA-6796648;Reactome: R-HSA-3371453;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-69473;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5685938;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-6783310;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756	"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of HSF1-mediated heat shock response";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"G2/M DNA damage checkpoint";"PI3K-Akt signaling pathway";"HDR through Single Strand Annealing (SSA)";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"mTOR signaling pathway";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation"
XP_053622048.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_053620413.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_053610180.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_053605036.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle"
XP_053602036.1	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
XP_053611903.1	7	KEGG: 00051+3.1.3.11;KEGG: 00030+3.1.3.11;Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00710+3.1.3.11;KEGG: 00680+3.1.3.11;KEGG: 00010+3.1.3.11	"Fructose and mannose metabolism";"Pentose phosphate pathway";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Glycolysis / Gluconeogenesis"
XP_053599944.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_053620098.1	57	Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-6798695;Reactome: R-HSA-174113	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1"
XP_053613704.1	4	Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-210991;Reactome: R-HSA-352230	"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Basigin interactions";"Amino acid transport across the plasma membrane"
XP_053614238.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053611776.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-442982	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_053623130.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053611647.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053606517.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053600438.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053625606.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053606371.1	4	Reactome: R-HSA-156581;Reactome: R-HSA-6790901;Reactome: R-HSA-6782315;Reactome: R-HSA-72764	"Methylation";"rRNA modification in the nucleus and cytosol";"tRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination"
XP_053613290.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_053615680.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053611433.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_053611678.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053612338.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053600921.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_053603957.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557	"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis"
XP_053606456.1	13	KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-4061;MetaCyc: PWY-6370;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-196836;MetaCyc: PWY-7533;MetaCyc: PWY-2261;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;KEGG: 00053+1.8.5.1	"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Glutathione-mediated detoxification I";"Ascorbate recycling (cytosolic)";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Vitamin C (ascorbate) metabolism";"Gliotoxin biosynthesis";"Ascorbate glutathione cycle";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Ascorbate and aldarate metabolism"
XP_053618251.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053614080.1	22	Reactome: R-HSA-6811558;Reactome: R-HSA-5467348;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-2500257	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Truncations of AMER1 destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"RAF activation";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"Resolution of Sister Chromatid Cohesion"
XP_053602364.1	18	MetaCyc: PWY-5084;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;KEGG: 00640+1.8.1.4;KEGG: 00310+1.8.1.4;Reactome: R-HSA-6783984;Reactome: R-HSA-70268;KEGG: 00020+1.8.1.4;Reactome: R-HSA-71403;MetaCyc: PWY-5046;Reactome: R-HSA-70895;KEGG: 00620+1.8.1.4;KEGG: 00280+1.8.1.4;Reactome: R-HSA-71064;KEGG: 00010+1.8.1.4;KEGG: 00260+1.8.1.4;KEGG: 00380+1.8.1.4;Reactome: R-HSA-389661	"2-oxoglutarate decarboxylation to succinyl-CoA";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Propanoate metabolism";"Lysine degradation";"Glycine degradation";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Branched-chain amino acid catabolism";"Pyruvate metabolism";"Valine, leucine and isoleucine degradation";"Lysine catabolism";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation"
XP_053612324.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_053622077.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053625077.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_053605364.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170;Reactome: R-HSA-216083	"ECM proteoglycans";"Molecules associated with elastic fibres";"Syndecan interactions";"Integrin cell surface interactions"
XP_053604252.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053623312.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053602160.1	1	Reactome: R-HSA-73621	"Pyrimidine catabolism"
XP_053609314.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-7112;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842	"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification II"
XP_053602815.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_053599831.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053624481.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053614764.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_053601307.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053602209.1	3	KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999;Reactome: R-HSA-159740	"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors"
XP_053610099.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053623066.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_053624239.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053613156.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_053615995.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_053606472.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053610135.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_053621746.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053614197.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053604307.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012	"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053618409.1	2	Reactome: R-HSA-3000178;MetaCyc: PWY-7511	"ECM proteoglycans";"Protein ubiquitination"
XP_053611764.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053609841.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053618699.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_053605594.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_053617344.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053622337.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_053621239.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_053616189.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053610476.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-2871796;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580	"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"Oxidative Stress Induced Senescence"
XP_053609694.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-73856	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination"
XP_053621361.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053615078.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053606519.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053619490.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053611649.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053612078.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_053619600.1	3	Reactome: R-HSA-381038;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
XP_053599910.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053620526.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_053602451.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053601417.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053610945.1	6	Reactome: R-HSA-8950505;MetaCyc: PWY-6854;Reactome: R-HSA-8862803;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Ethylene biosynthesis III (microbes)";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis"
XP_053623625.1	10	Reactome: R-HSA-200425;Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756	"Carnitine metabolism";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Lipophagy";"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation"
XP_053616567.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_053625927.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053621990.1	17	MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;Reactome: R-HSA-200425;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6679;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"Aflatoxin biosynthesis";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Jadomycin biosynthesis";"Pyruvate metabolism";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_053610767.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053615332.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053612332.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053600520.1	8	Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-5140745;Reactome: R-HSA-432720	"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Gap junction degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis"
XP_053611672.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053621505.1	42	Reactome: R-HSA-427389;Reactome: R-HSA-5693607;Reactome: R-HSA-427359;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-9610379;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-1221632;Reactome: R-HSA-3214842;Reactome: R-HSA-5693565;Reactome: R-HSA-73728;Reactome: R-HSA-8936459;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-4551638;Reactome: R-HSA-2299718;Reactome: R-HSA-427413;Reactome: R-HSA-3214847;Reactome: R-HSA-3214858;Reactome: R-HSA-171306;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-5625886;Reactome: R-HSA-110330;Reactome: R-HSA-212300;Reactome: R-HSA-5334118;Reactome: R-HSA-606279;Reactome: R-HSA-110331;Reactome: R-HSA-2559586;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-5578749;Reactome: R-HSA-8939236;Reactome: R-HSA-977225;Reactome: R-HSA-912446;Reactome: R-HSA-3214815;Reactome: R-HSA-9018519;Reactome: R-HSA-9609690;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-5617472	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Processing of DNA double-strand break ends";"SIRT1 negatively regulates rRNA expression";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Late Events";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Meiotic synapsis";"HDMs demethylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Opening";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of chromatin organization proteins";"Condensation of Prophase Chromosomes";"NoRC negatively regulates rRNA expression";"HATs acetylate histones";"RMTs methylate histone arginines";"Packaging Of Telomere Ends";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recognition and association of DNA glycosylase with site containing an affected purine";"PRC2 methylates histones and DNA";"DNA methylation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Cleavage of the damaged purine";"DNA Damage/Telomere Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Transcriptional regulation by small RNAs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Amyloid fiber formation";"Meiotic recombination";"HDACs deacetylate histones";"Estrogen-dependent gene expression";"HCMV Early Events";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_053601055.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053600902.1	56	Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-75815	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D"
XP_053613178.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053619036.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_053604258.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_053624685.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053617948.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-113507	"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation"
XP_053614536.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053619352.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053614214.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_053616773.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-381183	"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_053616906.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_053616617.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053613407.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053610458.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053599645.1	11	MetaCyc: PWY-6608;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6607;MetaCyc: PWY-5381;MetaCyc: PWY-6606;KEGG: 00230+3.1.3.5;KEGG: 00240+3.1.3.5;MetaCyc: PWY-7185;MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-7821	"Guanosine nucleotides degradation III";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation II";"Purine metabolism";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Tunicamycin biosynthesis"
XP_053601547.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_053622085.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053601258.1	18	KEGG: 00401+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00220+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00400+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6643;MetaCyc: PWY-7115	"Novobiocin biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"Sulfolactate degradation III";"Arginine biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine and proline metabolism";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Cysteine and methionine metabolism";"(R)-cysteate degradation";"Alanine, aspartate and glutamate metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_053621685.1	8	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053615144.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053607590.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053622953.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_053601874.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053600753.1	7	KEGG: 00330+3.5.3.1;MetaCyc: PWY-6922;MetaCyc: PWY-31;KEGG: 00220+3.5.3.1;Reactome: R-HSA-70635;MetaCyc: PWY-4984;MetaCyc: PWY-46	"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Canavanine degradation";"Arginine biosynthesis";"Urea cycle";"Urea cycle";"Putrescine biosynthesis III"
XP_053613020.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053603060.1	12	MetaCyc: PWY-5278;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.7.4;Reactome: R-HSA-2408550;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5340	"Sulfite oxidation III";"Monobactam biosynthesis";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Transport and synthesis of PAPS";"Purine metabolism";"Sulfur metabolism";"Selenate reduction";"Selenocompound metabolism";"Sulfate activation for sulfonation"
XP_053612340.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_053602789.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression"
XP_053619954.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_053617504.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_053622166.1	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_053612928.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053605968.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053617979.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053612901.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_053599661.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053620212.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053604547.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053608487.1	8	Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Activation of RAC1";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053604740.1	3	MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315	"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol"
XP_053624505.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053623698.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053605655.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_053606107.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_053618327.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_053623408.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053621192.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053600269.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_053604055.1	13	KEGG: 00740+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00500+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00230+3.6.1.66;KEGG: 00760+3.6.1.9;Reactome: R-HSA-74259;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7206	"Riboflavin metabolism";"Tunicamycin biosynthesis";"Starch and sucrose metabolism";"Purine metabolism";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Purine catabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides dephosphorylation"
XP_053613317.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053608959.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
XP_053617651.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053624550.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053611232.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053600155.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053599920.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_053611467.1	14	Reactome: R-HSA-192823;Reactome: R-HSA-2022377;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557	"Viral mRNA Translation";"Metabolism of Angiotensinogen to Angiotensins";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis"
XP_053604000.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053615694.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_053615404.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053610644.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053607435.1	7	MetaCyc: PWY-6363;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism"
XP_053603913.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-975957	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053620201.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053601714.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053615841.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053604453.1	3	Reactome: R-HSA-5362798;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_053618156.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053603475.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053610253.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_053600440.1	3	Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane"
XP_053611387.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053616846.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053605825.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5469	"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Sesamin biosynthesis"
XP_053623395.1	18	MetaCyc: PWY-5172;KEGG: 00640+6.2.1.5;Reactome: R-HSA-75105;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5537;MetaCyc: PWY-6969;Reactome: R-HSA-6798695;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5690;MetaCyc: PWY-6728;Reactome: R-HSA-163765;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5913	"Acetyl-coa biosynthesis III (from citrate)";"Propanoate metabolism";"Fatty acyl-CoA biosynthesis";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Neutrophil degranulation";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"ChREBP activates metabolic gene expression";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)"
XP_053601578.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-5610787	"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state"
XP_053605580.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053614758.1	2	MetaCyc: PWY-6938;Reactome: R-HSA-430039	"NADH repair";"mRNA decay by 5' to 3' exoribonuclease"
XP_053625042.1	2	KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608	"Aminoacyl-tRNA biosynthesis";"Platelet degranulation"
XP_053622363.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053607152.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_053599682.1	16	Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-176412	"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Phosphorylation of the APC/C"
XP_053616436.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_053623322.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053608489.1	8	Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Activation of RAC1";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_053613937.1	7	Reactome: R-HSA-389661;Reactome: R-HSA-71064;KEGG: 00020+2.3.1.61;KEGG: 00380+2.3.1.61;KEGG: 00310+2.3.1.61;Reactome: R-HSA-71403;MetaCyc: PWY-5084	"Glyoxylate metabolism and glycine degradation";"Lysine catabolism";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_053621468.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_053615110.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_053625483.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_053625370.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053611094.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_053619173.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_053621630.1	4	Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_053600911.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053622483.1	3	MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1	"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation"
XP_053620092.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_053606109.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_053619484.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_053618329.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_053625174.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_053618290.1	56	Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880	"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Neddylation";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases"
XP_053613251.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_053609338.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_053601000.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs"
XP_053613319.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053600267.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_053610227.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_053616175.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_053608204.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_053611826.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053610122.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_053624504.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053600162.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053621320.1	5	Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-6814122	"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053625397.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053600305.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_053603827.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053624979.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787	"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Hedgehog 'off' state"
XP_053614018.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_053607931.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053618277.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053605654.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_053606686.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053605216.1	8	KEGG: 00380+3.5.1.9;MetaCyc: PWY-5651;MetaCyc: PWY-7734;MetaCyc: PWY-7717;MetaCyc: PWY-7765;KEGG: 00630+3.5.1.9;MetaCyc: PWY-6309;MetaCyc: PWY-7733	"Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Quinoxaline-2-carboxylate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Glyoxylate and dicarboxylate metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxyquinaldate biosynthesis"
XP_053602654.1	3	Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053609628.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053613242.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_053604054.1	6	MetaCyc: PWY-5723;KEGG: 00710+5.1.3.1;MetaCyc: PWY-1861;KEGG: 00040+5.1.3.1;Reactome: R-HSA-71336;KEGG: 00030+5.1.3.1	"Rubisco shunt";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_053607412.1	2	Reactome: R-HSA-500753;Reactome: R-HSA-73621	"Pyrimidine biosynthesis";"Pyrimidine catabolism"
XP_053605243.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053615450.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_053601146.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_053608817.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_053616288.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053615145.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053605501.1	32	Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-8851708;Reactome: R-HSA-72086	"FGFR2 alternative splicing";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"Signaling by FGFR2 IIIa TM";"mRNA Capping"
XP_053615003.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_053602528.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053619518.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053603659.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053603002.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_053619430.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_053616953.1	12	MetaCyc: PWY-7385;KEGG: 00680+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00010+4.1.2.13;KEGG: 00030+4.1.2.13	"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway"
XP_053622051.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_053608196.1	16	Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-5693571;Reactome: R-HSA-69473	"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Estrogen-dependent gene expression";"HATs acetylate histones";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint"
XP_053607810.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053604798.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053625773.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_053624138.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167172	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome"
XP_053611947.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053621651.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053620280.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_053600706.1	5	Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399;Reactome: R-HSA-1912408	"Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Transcription and Translation"
XP_053622084.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053599644.1	11	MetaCyc: PWY-6606;MetaCyc: PWY-5381;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6607;MetaCyc: PWY-6608;MetaCyc: PWY-7821;MetaCyc: PWY-6596;MetaCyc: PWY-5695;KEGG: 00240+3.1.3.5;MetaCyc: PWY-7185;KEGG: 00230+3.1.3.5	"Guanosine nucleotides degradation II";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Tunicamycin biosynthesis";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"Purine metabolism"
XP_053607548.1	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_053611018.1	4	KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202	"Arginine and proline metabolism";"Spermidine biosynthesis III";"Cysteine and methionine metabolism";"Metabolism of polyamines"
XP_053618833.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053602681.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_053621504.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053606211.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_053607223.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_053623576.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_053600884.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053618997.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_053602477.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_053624124.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053601054.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053600960.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7587;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51	"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism"
XP_053625567.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-1362409	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis"
XP_053613426.1	4	KEGG: 00510+2.4.1.260;KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_053599769.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053608779.1	9	MetaCyc: PWY-6142;MetaCyc: PWY-8086;KEGG: 00720+6.4.1.1;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;Reactome: R-HSA-3371599;KEGG: 00020+6.4.1.1;Reactome: R-HSA-70263;Reactome: R-HSA-196780	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Biotin transport and metabolism"
XP_053623089.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053604081.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053611095.1	3	Reactome: R-HSA-392517;Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Rap1 signalling";"Ca2+ pathway";"cGMP effects"
XP_053625399.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_053600046.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_053624821.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_053625220.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053619485.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053618279.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_053602838.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053625175.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_053607763.1	7	MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7790;MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+2.4.2.10	"UMP biosynthesis III";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"UMP biosynthesis II";"UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism"
XP_053617723.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_053614139.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_053616174.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_053601343.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_053617642.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053608205.1	16	Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938	"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"HATs acetylate histones";"Estrogen-dependent gene expression";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)"
XP_053609392.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_053604715.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_053618103.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053607259.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_053626110.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053625436.1	11	Reactome: R-HSA-71403;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.42;KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-7254;MetaCyc: PWY-6549;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-7124	"Citric acid cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"L-glutamine biosynthesis III";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Ethylene biosynthesis V (engineered)"
XP_053603657.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_053600608.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_053608393.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_053610206.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053623272.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053612980.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053601406.1	7	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2173796	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_053607434.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053620378.1	57	Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-6798695;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128	"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Neutrophil degranulation";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"UCH proteinases";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling"
XP_053625619.1	2	Reactome: R-HSA-532668;Reactome: R-HSA-6798695	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation"
XP_053618523.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053599573.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism"
XP_053611949.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053619900.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_053603474.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053609562.1	3	Reactome: R-HSA-140837;Reactome: R-HSA-111471;Reactome: R-HSA-9645722	"Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"
XP_053619341.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053619522.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053606091.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_053617388.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053621821.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053624297.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053602662.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7036	"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II"
XP_053608646.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_053603742.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053606788.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053604316.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_053603623.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053620235.1	3	Reactome: R-HSA-6783310;Reactome: R-HSA-110314;Reactome: R-HSA-5689880	"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases"
XP_053616030.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053600154.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053612743.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_053607691.1	2	KEGG: 00500+3.2.1.26;KEGG: 00052+3.2.1.26	"Starch and sucrose metabolism";"Galactose metabolism"
XP_053618248.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053625569.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-5620924	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"Intraflagellar transport"
XP_053613285.1	3	Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins"
XP_053610118.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_053612405.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_053615716.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_053604062.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053599767.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053614022.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_053615405.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053616606.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053613416.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_053616496.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053613705.1	4	Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-352230;Reactome: R-HSA-210991	"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Amino acid transport across the plasma membrane";"Basigin interactions"
XP_053599945.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_053610910.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053624802.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-2173788	"UCH proteinases";"Downregulation of TGF-beta receptor signaling"
XP_053613833.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053616261.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053624771.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_053601503.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_053603250.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_053617648.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053625187.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053611028.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_053601068.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events"
XP_053619477.1	14	Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897	"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes"
XP_053624310.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053603779.1	56	Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-174113	"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1"
XP_053624114.1	6	Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis"
XP_053618426.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_053614163.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_053604123.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053605442.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_053614225.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_053604265.1	4	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;KEGG: 00790+4.6.1.17	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis"
XP_053614374.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network"
XP_053608386.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-165054	"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA"
XP_053616339.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053602083.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_053601241.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053609398.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053617984.1	5	KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403	"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling"
XP_053618230.1	24	Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025	"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation"
XP_053604683.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_053619121.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053612188.1	12	KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-451308;Reactome: R-HSA-399719;MetaCyc: PWY-7221	"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Activation of Ca-permeable Kainate Receptor";"Trafficking of AMPA receptors";"Guanosine ribonucleotides de novo biosynthesis"
XP_053625090.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053612554.1	4	Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis"
XP_053608002.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053608659.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-113501	"Polymerase switching";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_053622090.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy"
XP_053601265.1	5	MetaCyc: PWY-7817;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667	"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I"
XP_053602840.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053613306.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053623998.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_053602955.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_053606116.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053616079.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_053620294.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_053609003.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_053619528.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053620129.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053624690.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_053609935.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_053607422.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053613277.1	3	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_053615601.1	3	MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_053618867.1	5	Reactome: R-HSA-3108214;Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329	"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine"
XP_053603748.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053612491.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_053602668.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053611956.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053603817.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_053619216.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053600890.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-3232118;Reactome: R-HSA-5693571	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"SUMOylation of transcription factors";"Nonhomologous End-Joining (NHEJ)"
XP_053621310.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053614028.1	27	Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-180746	"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein"
XP_053604068.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053604503.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_053620689.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_053621114.1	6	MetaCyc: PWY-6344;MetaCyc: PWY-6922;MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;Reactome: R-HSA-8964539	"L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism"
XP_053626047.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053618242.1	18	MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Synthesis of PA";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC"
XP_053613999.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_053608623.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053609695.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-159230	"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA"
XP_053624140.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation"
XP_053626078.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate"
XP_053610101.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053624344.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053614012.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053620966.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053610128.1	6	KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;MetaCyc: PWY-7900;MetaCyc: PWY-622;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1	"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_053622189.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053619479.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_053625189.1	6	MetaCyc: PWY-5651;KEGG: 00380+1.14.13.9;MetaCyc: PWY-7717;MetaCyc: PWY-6309;MetaCyc: PWY-7765;Reactome: R-HSA-71240	"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan catabolism"
XP_053607737.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053613248.1	20	MetaCyc: PWY-7291;Reactome: R-HSA-9033241;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-6920;MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-735	"Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis"
XP_053603613.1	4	Reactome: R-HSA-9614399;Reactome: R-HSA-9615017;Reactome: R-HSA-5674400;Reactome: R-HSA-198693	"Regulation of localization of FOXO transcription factors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the nucleus"
XP_053614366.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_053607650.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_053624029.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053603021.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053610134.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_053612562.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_053602341.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053601792.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053616337.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053615562.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-211981;Reactome: R-HSA-211945;Reactome: R-HSA-8937144;Reactome: R-HSA-1989781	"Endogenous sterols";"Xenobiotics";"Phase I - Functionalization of compounds";"Aryl hydrocarbon receptor signalling";"PPARA activates gene expression"
XP_053614486.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053611765.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053600286.1	3	Reactome: R-HSA-727802;Reactome: R-HSA-6787639;Reactome: R-HSA-5619078	"Transport of nucleotide sugars";"GDP-fucose biosynthesis";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)"
XP_053599620.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053602900.1	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_053623184.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_053618670.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_053624455.1	3	Reactome: R-HSA-212676;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361	"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins"
XP_053623380.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053617345.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits"
XP_053614741.1	7	Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-110331;Reactome: R-HSA-171306	"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged purine";"Packaging Of Telomere Ends"
XP_053618513.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_053615274.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_053612325.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_053609980.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_053602102.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_053612274.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053618088.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053613103.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053623247.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053609315.1	10	MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13	"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism"
XP_053607542.1	7	Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-198323;Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-5674400	"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Macroautophagy";"AKT phosphorylates targets in the cytosol";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_053617361.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_053625823.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053605814.1	4	Reactome: R-HSA-9018519;Reactome: R-HSA-3371497;Reactome: R-HSA-3371568;Reactome: R-HSA-8939211	"Estrogen-dependent gene expression";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Attenuation phase";"ESR-mediated signaling"
XP_053603393.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-434316	"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_053620127.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053623151.1	11	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3270619	"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"E3 ubiquitin ligases ubiquitinate target proteins";"mTOR signaling pathway";"Human cytomegalovirus infection";"IRF3-mediated induction of type I IFN"
XP_053610508.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053613557.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053617481.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053610521.1	17	Reactome: R-HSA-450321;Reactome: R-HSA-975163;Reactome: R-HSA-937072;Reactome: R-HSA-5689880;Reactome: R-HSA-5357956;Reactome: R-HSA-168638;Reactome: R-HSA-9645460;Reactome: R-HSA-9014325;Reactome: R-HSA-2871837;Reactome: R-HSA-445989;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-450302;Reactome: R-HSA-4086398;Reactome: R-HSA-937042	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Ub-specific processing proteases";"TNFR1-induced NFkappaB signaling pathway";"NOD1/2 Signaling Pathway";"Alpha-protein kinase 1 signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"FCERI mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"activated TAK1 mediates p38 MAPK activation";"Ca2+ pathway";"IRAK2 mediated activation of TAK1 complex"
XP_053618869.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-3108214	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins"
XP_053611012.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_053625210.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053603819.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_053599733.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_053626049.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053612294.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053625441.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053608067.1	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Cyanoamino acid metabolism"
XP_053618027.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_053604772.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_053605169.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_053610090.1	12	Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-427413;Reactome: R-HSA-1834949;Reactome: R-HSA-73863;Reactome: R-HSA-76066;Reactome: R-HSA-73762	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"NoRC negatively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Initiation"
XP_053623809.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_053603373.1	5	Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines"
XP_053614868.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053604828.1	3	KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753;MetaCyc: PWY-5686	"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I"
XP_053625786.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053600986.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053604801.1	7	Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6798695	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Neutrophil degranulation"
XP_053620188.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_053619589.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053611632.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053611552.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053624230.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053613320.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053615689.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_053608584.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation"
XP_053617407.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_053610653.1	8	MetaCyc: PWY-2301;MetaCyc: PWY-6580;MetaCyc: PWY-6372;MetaCyc: PWY-6664;KEGG: 00562+5.5.1.4;Reactome: R-HSA-1855183;MetaCyc: PWY-4661;KEGG: 00521+5.5.1.4	"Myo-inositol biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Di-myo-inositol phosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Streptomycin biosynthesis"
XP_053600031.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits"
XP_053610533.1	9	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-5674135;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"MAP2K and MAPK activation";"Regulation of PTEN gene transcription";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Neutrophil degranulation"
XP_053618114.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_053616982.1	3	KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_053614640.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053614089.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_053613948.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_053610244.1	5	Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5620922;Reactome: R-HSA-5610787;Reactome: R-HSA-5632684	"Activation of SMO";"Class B/2 (Secretin family receptors)";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'off' state";"Hedgehog 'on' state"
XP_053623583.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_053603882.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_053623018.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053610859.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_053611576.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_053608631.1	5	KEGG: 00533+2.4.1.68;KEGG: 00513+2.4.1.68;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68	"Glycosaminoglycan biosynthesis - keratan sulfate";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis"
XP_053615883.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053624242.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053600517.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053600371.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_053611640.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053625910.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_053607806.1	33	Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-141444;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-3232142;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-159230;Reactome: R-HSA-159236	"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of ubiquitinylation proteins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053599919.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_053625385.1	3	KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_053612974.1	18	MetaCyc: PWY-5913;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00630+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-7115;Reactome: R-HSA-70263;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-1622;MetaCyc: PWY-8086;MetaCyc: PWY-6969;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00680+1.1.1.37	"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Reductive TCA cycle II";"Formaldehyde assimilation I (serine pathway)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Cysteine and methionine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Methane metabolism"
XP_053617317.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053607073.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053612509.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_053600667.1	9	Reactome: R-HSA-2871809;Reactome: R-HSA-193648;Reactome: R-HSA-2029482;Reactome: R-HSA-114604;Reactome: R-HSA-416482;Reactome: R-HSA-4420097;Reactome: R-HSA-2871796;Reactome: R-HSA-5218920;Reactome: R-HSA-194840	"FCERI mediated Ca+2 mobilization";"NRAGE signals death through JNK";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade";"G alpha (12/13) signalling events";"VEGFA-VEGFR2 Pathway";"FCERI mediated MAPK activation";"VEGFR2 mediated vascular permeability";"Rho GTPase cycle"
XP_053610627.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053601772.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_053618690.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_053601355.1	3	MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57;MetaCyc: PWY-0	"Spermine and spermidine degradation I";"Arginine and proline metabolism";"Putrescine degradation III"
XP_053621230.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053623603.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053620581.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_053609117.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053622070.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053600863.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053610823.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053624546.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053611190.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_053618029.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_053602167.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_053620392.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053621088.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053616452.1	5	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-165181	"Macroautophagy";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB"
XP_053624513.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053614564.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-933541;Reactome: R-HSA-9013973;Reactome: R-HSA-918233;Reactome: R-HSA-936440	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6 mediated IRF7 activation";"TICAM1-dependent activation of IRF3/IRF7";"TRAF3-dependent IRF activation pathway";"Negative regulators of DDX58/IFIH1 signaling"
XP_053623978.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053601300.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_053623807.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-6798695;Reactome: R-HSA-1660661	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation";"Sphingolipid de novo biosynthesis"
XP_053614992.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_053626015.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053607946.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053609896.1	2	KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841	"Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_053608888.1	4	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis"
XP_053618344.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053626106.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053622342.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_053622063.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_053616961.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones"
XP_053606921.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_053603435.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-2132295	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation"
XP_053603950.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_053607913.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053604538.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053624285.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_053610857.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053613977.1	5	Reactome: R-HSA-4085001;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295	"Sialic acid metabolism";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism";"Neutrophil degranulation";"MHC class II antigen presentation"
XP_053619943.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053603152.1	7	Reactome: R-HSA-6798695;MetaCyc: PWY-7238;MetaCyc: PWY-6724;Reactome: R-HSA-70221;MetaCyc: PWY-5941;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25	"Neutrophil degranulation";"Sucrose biosynthesis II";"Starch degradation II";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Starch degradation V";"Starch and sucrose metabolism"
XP_053611256.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053617937.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053625944.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_053615153.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053611614.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-6802952	"Macroautophagy";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions"
XP_053603799.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_053619497.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053600519.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053619607.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_053612966.1	22	MetaCyc: PWY-7606;MetaCyc: PWY-7727;MetaCyc: PWY-7728;MetaCyc: PWY-7725;MetaCyc: PWY-7053;MetaCyc: PWY-5353;MetaCyc: PWY-6598;MetaCyc: PWY-7592;MetaCyc: PWY-7049;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7724;KEGG: 00062+4.2.1.134;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7726;MetaCyc: PWY-6958;MetaCyc: PWY-7035;MetaCyc: PWY-6433	"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_053599917.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053618942.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053625128.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053621285.1	42	Reactome: R-HSA-2559586;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-1912408;Reactome: R-HSA-5625886;Reactome: R-HSA-110330;Reactome: R-HSA-212300;Reactome: R-HSA-5334118;Reactome: R-HSA-606279;Reactome: R-HSA-3214815;Reactome: R-HSA-9018519;Reactome: R-HSA-9609690;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-5617472;Reactome: R-HSA-8939236;Reactome: R-HSA-5578749;Reactome: R-HSA-977225;Reactome: R-HSA-912446;Reactome: R-HSA-201722;Reactome: R-HSA-1221632;Reactome: R-HSA-3214841;Reactome: R-HSA-5693565;Reactome: R-HSA-3214842;Reactome: R-HSA-427389;Reactome: R-HSA-5693607;Reactome: R-HSA-427359;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-9610379;Reactome: R-HSA-3214847;Reactome: R-HSA-171306;Reactome: R-HSA-2559580;Reactome: R-HSA-3214858;Reactome: R-HSA-73728;Reactome: R-HSA-8936459;Reactome: R-HSA-5693571;Reactome: R-HSA-4551638;Reactome: R-HSA-69473;Reactome: R-HSA-2299718;Reactome: R-HSA-427413	"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Pre-NOTCH Transcription and Translation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recognition and association of DNA glycosylase with site containing an affected purine";"PRC2 methylates histones and DNA";"DNA methylation";"Deposition of new CENPA-containing nucleosomes at the centromere";"HDACs deacetylate histones";"Estrogen-dependent gene expression";"HCMV Early Events";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation by small RNAs";"Amyloid fiber formation";"Meiotic recombination";"Formation of the beta-catenin:TCF transactivating complex";"Meiotic synapsis";"PKMTs methylate histone lysines";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDMs demethylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Processing of DNA double-strand break ends";"SIRT1 negatively regulates rRNA expression";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Late Events";"HATs acetylate histones";"Packaging Of Telomere Ends";"Oxidative Stress Induced Senescence";"RMTs methylate histone arginines";"RNA Polymerase I Promoter Opening";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of chromatin organization proteins";"G2/M DNA damage checkpoint";"Condensation of Prophase Chromosomes";"NoRC negatively regulates rRNA expression"
XP_053615966.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053618811.1	5	KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-3341	"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)"
XP_053601538.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053621546.1	12	MetaCyc: PWY-5856;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5873;MetaCyc: PWY-5872;MetaCyc: PWY-5871;Reactome: R-HSA-2142789;MetaCyc: PWY-7233;MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-5855;MetaCyc: PWY-6708;MetaCyc: PWY-7230	"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)"
XP_053600472.1	16	Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-176412	"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Phosphorylation of the APC/C"
XP_053601965.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-165054	"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA"
XP_053604812.1	23	Reactome: R-HSA-8964616;Reactome: R-HSA-381676;Reactome: R-HSA-456926;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-392451;Reactome: R-HSA-9009391;Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-4086398;Reactome: R-HSA-418592;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-418555;Reactome: R-HSA-6814122;Reactome: R-HSA-500657;Reactome: R-HSA-392851;Reactome: R-HSA-392170;Reactome: R-HSA-400042	"G beta:gamma signalling through CDC42";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"G beta:gamma signalling through PI3Kgamma";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 1";"G alpha (i) signalling events";"G-protein activation";"G alpha (s) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Presynaptic function of Kainate receptors";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 12";"Adrenaline,noradrenaline inhibits insulin secretion"
XP_053610629.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053622134.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_053605794.1	15	Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-3769402;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747;Reactome: R-HSA-111465;Reactome: R-HSA-5467333;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-5689896;Reactome: R-HSA-5358749	"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"APC truncation mutants are not K63 polyubiquitinated";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases";"S37 mutants of beta-catenin aren't phosphorylated"
XP_053604300.1	7	Reactome: R-HSA-9029569;Reactome: R-HSA-8943724;Reactome: R-HSA-5625886;Reactome: R-HSA-3214842;Reactome: R-HSA-983231;Reactome: R-HSA-3214815;Reactome: R-HSA-9018519	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN gene transcription";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDMs demethylate histones";"Factors involved in megakaryocyte development and platelet production";"HDACs deacetylate histones";"Estrogen-dependent gene expression"
XP_053602794.1	26	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors"
XP_053605255.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053625134.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_053621670.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053621082.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053618651.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053618531.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053605336.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053610084.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053619575.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053606414.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
XP_053607367.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion"
XP_053611854.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053620852.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_053601747.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053616610.1	2	Reactome: R-HSA-9020702;Reactome: R-HSA-6798695	"Interleukin-1 signaling";"Neutrophil degranulation"
XP_053614881.1	4	Reactome: R-HSA-1268020;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial protein import";"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053601540.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_053613053.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053603631.1	3	MetaCyc: PWY-5963;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9	"Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_053606520.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053624559.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053618979.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053605052.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_053599929.1	6	Reactome: R-HSA-73930;Reactome: R-HSA-73933;Reactome: R-HSA-110362;Reactome: R-HSA-110373;Reactome: R-HSA-5651801;Reactome: R-HSA-110357	"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of Abasic Sites (AP sites)";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1"
XP_053602052.1	7	MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6122;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14	"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism"
XP_053623028.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053609883.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_053604652.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053608797.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_053611335.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_053625502.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053615675.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053624416.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_053606304.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_053621639.1	4	KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558	"Cysteine and methionine metabolism";"Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine"
XP_053624997.1	11	Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-164378	"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Hedgehog 'off' state";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling"
XP_053611075.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_053608360.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053606100.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-390471;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation"
XP_053613802.1	14	MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725	"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_053613771.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_053616390.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053625122.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-936964	"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_053606269.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_053622122.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_053610397.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_053607597.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053610051.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053603067.1	2	KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"Glycine degradation"
XP_053609372.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_053624082.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053618138.1	9	KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52	"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Other glycan degradation"
XP_053621306.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053606331.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_053609129.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_053619169.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_053611736.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_053614278.1	4	Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72;MetaCyc: PWY-8026;Reactome: R-HSA-6807062	"Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol"
XP_053620003.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053617704.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053625682.1	10	MetaCyc: PWY-6536;MetaCyc: PWY-6535;KEGG: 00640+2.6.1.19;MetaCyc: PWY-6537;MetaCyc: PWY-4321;KEGG: 00410+2.6.1.19;KEGG: 00650+2.6.1.19;Reactome: R-HSA-916853;KEGG: 00250+2.6.1.19;MetaCyc: PWY-5022	"4-aminobutanoate degradation III";"4-aminobutanoate degradation I";"Propanoate metabolism";"4-aminobutanoate degradation II";"L-glutamate degradation IV";"beta-Alanine metabolism";"Butanoate metabolism";"Degradation of GABA";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation V"
XP_053609294.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_053611881.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053609755.1	5	MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;KEGG: 00785+6.3.1.20;MetaCyc: PWY-7382;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation"
XP_053622682.1	6	MetaCyc: PWY-7426;Reactome: R-HSA-975578;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143	"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_053608480.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_053601514.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053617172.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053607204.1	3	Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400	"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER"
XP_053625793.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053606830.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053611558.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes"
XP_053612378.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053607369.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_053616253.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053615378.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053604822.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053611473.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_053600529.1	27	Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-165054	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA"
XP_053616769.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-381183	"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_053624557.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053607489.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053618821.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria"
XP_053605607.1	5	MetaCyc: PWY-3341;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981	"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)"
XP_053605916.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_053620695.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_053608152.1	4	Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594	"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events"
XP_053620716.1	10	MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484	"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)"
XP_053620405.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053605497.1	16	Reactome: R-HSA-1234176;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-983168;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-9010553;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-180585;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-8951664;Reactome: R-HSA-112382	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Regulation of expression of SLITs and ROBOs";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Vif-mediated degradation of APOBEC3G";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Neddylation";"Formation of RNA Pol II elongation complex"
XP_053622118.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_053599927.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_053613811.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823	"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_053611624.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053621248.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053601664.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053605943.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_053608799.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_053617044.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_053612235.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053624999.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_053606911.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053625511.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053621750.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053615024.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-606279	"Fanconi Anemia Pathway";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053607923.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_053621557.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053621637.1	4	Reactome: R-HSA-1614558;KEGG: 00430+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00270+1.13.11.20	"Degradation of cysteine and homocysteine";"Taurine and hypotaurine metabolism";"Taurine biosynthesis I";"Cysteine and methionine metabolism"
XP_053613140.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_053602064.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_053623012.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053626092.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053618297.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053606267.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_053617156.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053600260.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053609471.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_053626025.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-6798695	"WNT ligand biogenesis and trafficking";"Neutrophil degranulation"
XP_053608435.1	8	MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47;MetaCyc: PWY-7573;Reactome: R-HSA-6787639;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5739;MetaCyc: PWY-66;MetaCyc: PWY-5740	"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-mycosamine biosynthesis";"GDP-fucose biosynthesis";"Fructose and mannose metabolism";"GDP-D-perosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-L-colitose biosynthesis"
XP_053610175.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053610846.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053607599.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053625206.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_053599953.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_053612349.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_053617970.1	7	Reactome: R-HSA-1660662;MetaCyc: PWY-7841;MetaCyc: PWY-7839;MetaCyc: PWY-7836;MetaCyc: PWY-5129;MetaCyc: PWY-7838;KEGG: 00600+2.4.1.80	"Glycosphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid metabolism"
XP_053609127.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_053614558.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053611862.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053610436.1	5	Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_053603213.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_053624886.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_053610166.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_053600126.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053620928.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_053605728.1	11	Reactome: R-HSA-4043916;MetaCyc: PWY-7456;MetaCyc: PWY-7586;KEGG: 00051+5.3.1.8;MetaCyc: PWY-6992;Reactome: R-HSA-446205;KEGG: 00520+5.3.1.8;MetaCyc: PWY-882;MetaCyc: PWY-5659;MetaCyc: PWY-3861;MetaCyc: PWY-3881	"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism";"1,5-anhydrofructose degradation";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Mannitol degradation II";"Mannitol biosynthesis"
XP_053616682.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053599813.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-2022854;Reactome: R-HSA-5173105	"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis";"O-linked glycosylation"
XP_053603246.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_053604368.1	10	KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41;KEGG: 00332+2.7.2.11+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00332+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00330+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41	"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis"
XP_053619847.1	6	MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system"
XP_053614855.1	10	MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6397;MetaCyc: PWY-6317;MetaCyc: PWY-7344;Reactome: R-HSA-70370;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2	"D-galactose detoxification";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism"
XP_053602872.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867	"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex"
XP_053620340.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053615989.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053609754.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053606305.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_053622390.1	2	Reactome: R-HSA-5601884;Reactome: R-HSA-1221632	"PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis"
XP_053625229.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053608165.1	31	MetaCyc: PWYG-321;MetaCyc: PWY-5366;MetaCyc: PWY-8047;MetaCyc: PWY-7746;Reactome: R-HSA-163765;MetaCyc: PWY-5994;MetaCyc: PWY-6799;MetaCyc: PWY-4381;MetaCyc: PWY-7663;MetaCyc: PWY-5966-1;Reactome: R-HSA-75105;MetaCyc: PWY-5973;Reactome: R-HSA-199220;MetaCyc: PWY-5989;MetaCyc: PWY-7664;MetaCyc: PWY-6113;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;MetaCyc: PWY-5142;MetaCyc: PWY-7723;MetaCyc: PWY-6519;MetaCyc: PWY-8049;MetaCyc: PWY-7858;MetaCyc: PWY-5147;MetaCyc: PWY-6282;Reactome: R-HSA-9029558;MetaCyc: PWY-8012;MetaCyc: PWY-5367;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168;MetaCyc: PWY-5971	"";"Palmitoleate biosynthesis II (plants and bacteria)";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"Cis-vaccenate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Stearate biosynthesis II (bacteria and plants)";"Oleate biosynthesis IV (anaerobic)";"Superpathway of mycolate biosynthesis";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bacterial bioluminescence";"8-amino-7-oxononanoate biosynthesis I";"Pederin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis I (plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Mupirocin biosynthesis";"Petroselinate biosynthesis";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)"
XP_053611074.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_053606851.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_053611932.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053606162.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053622229.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053613860.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053623238.1	5	Reactome: R-HSA-8948751;Reactome: R-HSA-5545619;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"Regulation of PTEN stability and activity";"XAV939 inhibits tankyrase, stabilizing AXIN";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_053625194.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053618270.1	56	Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-2467813	"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids"
XP_053620934.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_053618192.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053610288.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053611783.1	2	Reactome: R-HSA-442982;Reactome: R-HSA-5673001	"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade"
XP_053607196.1	3	Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400	"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER"
XP_053601488.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_053613382.1	6	MetaCyc: PWY-2941;KEGG: 00300+4.3.3.7;MetaCyc: PWY-8088;KEGG: 00261+4.3.3.7;MetaCyc: PWY-5097;MetaCyc: PWY-2942	"L-lysine biosynthesis II";"Lysine biosynthesis";"Dipicolinate biosynthesis";"Monobactam biosynthesis";"L-lysine biosynthesis VI";"L-lysine biosynthesis III"
XP_053600359.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_053605470.1	10	KEGG: 05165+2.7.11.1;Reactome: R-HSA-201722;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5689880	"Human papillomavirus infection";"Formation of the beta-catenin:TCF transactivating complex";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"HATs acetylate histones";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Ub-specific processing proteases"
XP_053618990.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_053609098.1	3	Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999	"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
XP_053616502.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053616348.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053608086.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_053600967.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_053625767.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_053606960.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_053608904.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053614411.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_053608257.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_053607817.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053625573.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-1912420	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi"
XP_053619909.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_053610085.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053625458.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane"
XP_053611940.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053622458.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053621731.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053603605.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053601368.1	8	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Activation of RAC1"
XP_053611855.1	18	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-166208;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Formation of a pool of free 40S subunits"
XP_053617639.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053611301.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_053615423.1	2	Reactome: R-HSA-5627123;Reactome: R-HSA-8856828	"RHO GTPases activate PAKs";"Clathrin-mediated endocytosis"
XP_053620314.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_053604958.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_053607570.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553	"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs"
XP_053619439.1	9	KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52	"Other glycan degradation";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation"
XP_053603530.1	7	Reactome: R-HSA-2151201;KEGG: 00190+7.1.2.2;Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;MetaCyc: PWY-7980;Reactome: R-HSA-1268020	"Transcriptional activation of mitochondrial biogenesis";"Oxidative phosphorylation";"Cristae formation";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"ATP biosynthesis";"Mitochondrial protein import"
XP_053608428.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_053608691.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053614914.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053618468.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_053615987.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053626038.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053621329.1	3	MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403	"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_053625227.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053602065.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_053606181.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_053614692.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035	"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis"
XP_053613345.1	9	Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-110314;Reactome: R-HSA-8951664;Reactome: R-HSA-6782135;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Recognition of DNA damage by PCNA-containing replication complex";"Neddylation";"Dual incision in TC-NER";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER"
XP_053618757.1	14	KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-1483191;Reactome: R-HSA-75109;KEGG: 00600+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8051;KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8052;MetaCyc: PWY-7782;MetaCyc: PWY-8053	"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PC";"Triglyceride biosynthesis";"Sphingolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE";"Ether lipid metabolism";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis II"
XP_053618630.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053610483.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_053606013.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_053607563.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_053609106.1	3	Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999	"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
XP_053615459.1	9	Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-3928662;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-438066	"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"EPHB-mediated forward signaling";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_053610174.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053604665.1	6	Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695	"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism";"Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation"
XP_053612092.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053611692.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053603321.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_053603308.1	15	MetaCyc: PWY-6142;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-6886;KEGG: 00010+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Pyruvate metabolism"
XP_053602186.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_053622988.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_053615543.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053620694.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_053606588.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex"
XP_053609526.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053619566.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-69052	"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state"
XP_053625769.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_053608259.1	9	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053599567.1	10	MetaCyc: PWY-7199;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7184;Reactome: R-HSA-69205;MetaCyc: PWY-3841;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7198;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7187	"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"G1/S-Specific Transcription";"Folate transformations II (plants)";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_053611625.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053612516.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14	"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis"
XP_053608311.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_053613198.1	3	Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45	"Glycosphingolipid metabolism";"Other glycan degradation";"Sphingolipid metabolism"
XP_053617045.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053612234.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053618642.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053601515.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053615666.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_053604894.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_053601958.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053607819.1	13	Reactome: R-HSA-3928662;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416572;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-416482;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3928663	"EPHB-mediated forward signaling";"PI3K-Akt signaling pathway";"RHO GTPases Activate ROCKs";"Relaxin signaling pathway";"Sema4D induced cell migration and growth-cone collapse";"Thermogenesis";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"G alpha (12/13) signalling events";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"EPHA-mediated growth cone collapse"
XP_053619907.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_053608763.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053614312.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053613481.1	8	Reactome: R-HSA-5173105;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;MetaCyc: PWY-7922;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109	"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis"
XP_053617637.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053612201.1	13	MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;Reactome: R-HSA-2160916	"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"CS/DS degradation";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation"
XP_053615201.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_053609762.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053622644.1	3	Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558	"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine"
XP_053602268.1	5	Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693571	"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)"
XP_053609218.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_053619643.1	19	KEGG: 00230+2.7.4.6;Reactome: R-HSA-380320;MetaCyc: PWY-7222;Reactome: R-HSA-380270;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7224;MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7197	"Purine metabolism";"Recruitment of NuMA to mitotic centrosomes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"CMP phosphorylation";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation"
XP_053613677.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053612975.1	18	MetaCyc: PWY-6728;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-5913;KEGG: 00630+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-561;Reactome: R-HSA-70263;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-1622;MetaCyc: PWY-5392;MetaCyc: PWY-8086;MetaCyc: PWY-6969;KEGG: 00270+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7383	"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Cysteine and methionine metabolism";"Methane metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_053615836.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_053603412.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053615975.1	29	Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-427413;Reactome: R-HSA-6782210;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-75953;Reactome: R-HSA-5696400;Reactome: R-HSA-167160;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-5696395;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-72086	"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"NoRC negatively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation";"Dual Incision in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of Incision Complex in GG-NER";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping"
XP_053615781.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_053622464.1	3	KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669;Reactome: R-HSA-1483213	"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE"
XP_053612413.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_053618237.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053599629.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053607827.1	13	Reactome: R-HSA-3928662;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5627117;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-3928663;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"EPHB-mediated forward signaling";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"RHO GTPases Activate ROCKs";"G alpha (12/13) signalling events";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"Thermogenesis";"Sema4D induced cell migration and growth-cone collapse";"EPHA-mediated growth cone collapse";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_053624939.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_053608422.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053621407.1	15	Reactome: R-HSA-2173796;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-176034;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167200	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Interactions of Tat with host cellular proteins";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_053610496.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_053609674.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053624149.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053623672.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053614421.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_053614408.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_053618382.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_053603257.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_053624317.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_053619383.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053601703.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053615098.1	13	MetaCyc: PWY-7102;MetaCyc: PWY-7141;MetaCyc: PWY-7709;MetaCyc: PWY-7659;MetaCyc: PWY-7182;MetaCyc: PWY-7736;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-5123;MetaCyc: PWY-6859;MetaCyc: PWY-5122;MetaCyc: PWY-7721;MetaCyc: PWY-6383	"Bisabolene biosynthesis (engineered)";"(3S)-linalool biosynthesis";"(3R)-linalool biosynthesis";"Viridicatumtoxin biosynthesis";"Linalool biosynthesis I";"Stellatic acid biosynthesis";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis"
XP_053607002.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053625384.1	3	MetaCyc: PWY-6558;Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_053599857.1	26	Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-9013695;Reactome: R-HSA-3371568;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-9617629;Reactome: R-HSA-933541;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-8866907;Reactome: R-HSA-918233;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-3899300;Reactome: R-HSA-5617472;Reactome: R-HSA-3134973	"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Attenuation phase";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"Regulation of FOXO transcriptional activity by acetylation";"TRAF6 mediated IRF7 activation";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"TRAF3-dependent IRF activation pathway";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"RORA activates gene expression";"Estrogen-dependent gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SUMOylation of transcription cofactors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"
XP_053606582.1	1	Reactome: R-HSA-419771	"Opsins"
XP_053625982.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053600782.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_053609457.1	6	MetaCyc: PWY-6277;Reactome: R-HSA-73817;Reactome: R-HSA-196780;MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00230+6.3.4.13	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Biotin transport and metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism"
XP_053615303.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053613759.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_053622982.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_053608820.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053618860.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053611698.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053616112.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_053621317.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053620047.1	1	Reactome: R-HSA-73614	"Pyrimidine salvage"
XP_053605193.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_053614318.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_053608739.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_053615754.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_053609989.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_053619872.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053612295.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053622097.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053613685.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_053612754.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053618648.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490	"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins"
XP_053600116.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053607291.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652;Reactome: R-HSA-8948747	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PTEN localization"
XP_053623536.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_053613263.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053602718.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053602262.1	4	Reactome: R-HSA-379726;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6	"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_053626129.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053624407.1	13	Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-3928662;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5687128;Reactome: R-HSA-416476;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1	"NRAGE signals death through JNK";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Rho GTPase cycle";"EPHB-mediated forward signaling";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"MAPK6/MAPK4 signaling";"G alpha (q) signalling events";"Human papillomavirus infection";"G alpha (12/13) signalling events";"Thermogenesis"
XP_053618873.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053599823.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_053601964.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053616688.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053615218.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053605643.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_053609201.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053604016.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_053602722.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_053614179.1	7	Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation"
XP_053605878.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053607829.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053605795.1	15	Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-3769402;Reactome: R-HSA-5358751;Reactome: R-HSA-5689896;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-111465	"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"S45 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins"
XP_053622135.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053605254.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053599627.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053618239.1	18	MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC"
XP_053609666.1	56	Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346	"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Degradation of DVL";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis"
XP_053614322.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_053621409.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053609516.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053614203.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053609234.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053624147.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053604482.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053616128.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_053615526.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053611938.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053625945.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_053611796.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053608321.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053608542.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_053624319.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053619186.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway"
XP_053603259.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_053609543.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053619041.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_053607730.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053599859.1	26	Reactome: R-HSA-9013695;Reactome: R-HSA-3371568;Reactome: R-HSA-201722;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-933541;Reactome: R-HSA-9617629;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-8866907;Reactome: R-HSA-918233;Reactome: R-HSA-3134973;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-5617472;Reactome: R-HSA-3899300	"NOTCH4 Intracellular Domain Regulates Transcription";"Attenuation phase";"Formation of the beta-catenin:TCF transactivating complex";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"TRAF6 mediated IRF7 activation";"Regulation of FOXO transcriptional activity by acetylation";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"TRAF3-dependent IRF activation pathway";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"RORA activates gene expression";"Estrogen-dependent gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of transcription cofactors"
XP_053621284.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053611203.1	57	Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-6798695;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-180534	"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Degradation of DVL";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4"
XP_053626014.1	3	MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662	"Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_053613630.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_053617513.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_053612106.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_053613550.1	7	KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897;MetaCyc: PWY-5921	"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation"
XP_053613757.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053623094.1	11	MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-8053;Reactome: R-HSA-2029485;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4	"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Role of phospholipids in phagocytosis";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism"
XP_053610708.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053617670.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053599653.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_053603434.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"HCMV Early Events";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
XP_053621319.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053605396.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7	"Betanidin degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis"
XP_053619065.1	6	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;MetaCyc: PWY-6829;Reactome: R-HSA-6787450;MetaCyc: PWY-7285;MetaCyc: PWY-7286	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"Trna methylation (yeast)";"tRNA modification in the mitochondrion";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_053602396.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_053608093.1	9	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-5674135;Reactome: R-HSA-380972	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Neutrophil degranulation";"mTORC1-mediated signalling";"mTOR signalling";"MAP2K and MAPK activation";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_053608737.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_053625452.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053614924.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-9010553;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236	"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Degradation of DVL";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"UCH proteinases";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Regulation of expression of SLITs and ROBOs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_053623240.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053604525.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053610077.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053602281.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_053606611.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053601043.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053613468.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_053621937.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_053620548.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053620302.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053603047.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053614902.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053611269.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053612367.1	6	Reactome: R-HSA-5654712;Reactome: R-HSA-5654700;Reactome: R-HSA-9028731;Reactome: R-HSA-5673001;Reactome: R-HSA-5654693;Reactome: R-HSA-5654706	"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR2 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"RAF/MAP kinase cascade";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR3 signaling"
XP_053601229.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053618655.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053605327.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_053615367.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053610732.1	17	MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-7222;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7176	"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis"
XP_053611331.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053612671.1	14	Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_053614414.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053617499.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_053619020.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_053613207.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_053609806.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053623005.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053605010.1	6	Reactome: R-HSA-5632927;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358606	"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_053604610.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_053608144.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_053604458.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_053620223.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_053606998.1	2	KEGG: 00040+5.3.1.5;KEGG: 00051+5.3.1.5	"Pentose and glucuronate interconversions";"Fructose and mannose metabolism"
XP_053604573.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_053614071.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053623116.1	42	Reactome: R-HSA-427389;Reactome: R-HSA-5693607;Reactome: R-HSA-427359;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-9610379;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-1221632;Reactome: R-HSA-3214842;Reactome: R-HSA-5693565;Reactome: R-HSA-73728;Reactome: R-HSA-8936459;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-4551638;Reactome: R-HSA-2299718;Reactome: R-HSA-427413;Reactome: R-HSA-3214847;Reactome: R-HSA-171306;Reactome: R-HSA-3214858;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-110330;Reactome: R-HSA-5625886;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-606279;Reactome: R-HSA-110331;Reactome: R-HSA-2559586;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-5578749;Reactome: R-HSA-8939236;Reactome: R-HSA-977225;Reactome: R-HSA-912446;Reactome: R-HSA-3214815;Reactome: R-HSA-9609690;Reactome: R-HSA-9018519;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-5617472	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Processing of DNA double-strand break ends";"SIRT1 negatively regulates rRNA expression";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Late Events";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Meiotic synapsis";"HDMs demethylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Opening";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"SUMOylation of chromatin organization proteins";"Condensation of Prophase Chromosomes";"NoRC negatively regulates rRNA expression";"HATs acetylate histones";"Packaging Of Telomere Ends";"RMTs methylate histone arginines";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA methylation";"PRC2 methylates histones and DNA";"Deposition of new CENPA-containing nucleosomes at the centromere";"Cleavage of the damaged purine";"DNA Damage/Telomere Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Transcriptional regulation by small RNAs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Amyloid fiber formation";"Meiotic recombination";"HDACs deacetylate histones";"HCMV Early Events";"Estrogen-dependent gene expression";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_053600656.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053621728.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053621463.1	56	Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-9010553	"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs"
XP_053620412.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053613898.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_053613352.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_053601610.1	3	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation"
XP_053619407.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_053602353.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053624701.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_053608056.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_053611885.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053600469.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_053610429.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_053614100.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053611727.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053612790.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053601560.1	12	MetaCyc: PWY-1187;MetaCyc: PWY-6842;MetaCyc: PWY-2821;MetaCyc: PWY-7901;KEGG: 00380+2.6.1.7;MetaCyc: PWY-801;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6936;KEGG: 00270+4.4.1.13;MetaCyc: PWY-601;MetaCyc: PWY-6309;Reactome: R-HSA-71240	"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tyrosine";"Tryptophan metabolism";"Homocysteine and cysteine interconversion";"Selenocompound metabolism";"Seleno-amino acid biosynthesis (plants)";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tryptophan";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism"
XP_053620086.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_053611902.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_053607119.1	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
XP_053604390.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053605704.1	9	MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-5743;Reactome: R-HSA-1475029	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide"
XP_053619178.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_053602704.1	14	KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-5981;MetaCyc: PWY-7411	"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)"
XP_053613036.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053604229.1	6	MetaCyc: PWY-6908;MetaCyc: PWY-7356;MetaCyc: PWY-6898;MetaCyc: PWY-6907;Reactome: R-HSA-196819;KEGG: 00730+2.7.6.2	"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage IV (yeast)";"Thiamine salvage III";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism";"Thiamine metabolism"
XP_053614155.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_053613484.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053622641.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053611432.1	3	Reactome: R-HSA-174403;MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9	"Glutathione synthesis and recycling";"Gamma-glutamyl cycle";"Glutathione metabolism"
XP_053615369.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_053602290.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_053605290.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053611267.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053614830.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053608314.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053612231.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053600240.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_053623346.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_053618358.1	20	Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-735	"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"Propanoate metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis"
XP_053618825.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_053620691.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_053603120.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_053613160.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053623313.1	7	KEGG: 00020+2.3.1.61;Reactome: R-HSA-71064;Reactome: R-HSA-389661;Reactome: R-HSA-71403;MetaCyc: PWY-5084;KEGG: 00310+2.3.1.61;KEGG: 00380+2.3.1.61	"Citrate cycle (TCA cycle)";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism"
XP_053613364.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_053609913.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73863	"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_053610171.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_053613594.1	13	Reactome: R-HSA-8866427;Reactome: R-HSA-177504;Reactome: R-HSA-8856825;Reactome: R-HSA-5140745;Reactome: R-HSA-8856828;Reactome: R-HSA-182218;Reactome: R-HSA-5099900;Reactome: R-HSA-167590;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-416993;Reactome: R-HSA-3928665;Reactome: R-HSA-8964038	"VLDLR internalisation and degradation";"Retrograde neurotrophin signalling";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation";"Recycling pathway of L1";"MHC class II antigen presentation";"Trafficking of GluR2-containing AMPA receptors";"EPH-ephrin mediated repulsion of cells";"LDL clearance"
XP_053609475.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_053626021.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_053610714.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557	"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis"
XP_053620763.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_053617064.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053606473.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053611440.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053608912.1	3	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394;Reactome: R-HSA-3214847	"UCH proteinases";"DNA Damage Recognition in GG-NER";"HATs acetylate histones"
XP_053619409.1	10	MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-5667	"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Synthesis of PA";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I"
XP_053617780.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2173788;Reactome: R-HSA-2500257;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-141444;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Downregulation of TGF-beta receptor signaling";"Resolution of Sister Chromatid Cohesion";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Circadian Clock";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053600467.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_053603078.1	3	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_053621186.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053601891.1	4	Reactome: R-HSA-4720454;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.261	"Defective ALG9 causes ALG9-CDG (CDG-1l)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis"
XP_053619284.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_053614267.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_053617169.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_053600776.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_053602178.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-5578775	"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"RAF activation";"Interferon gamma signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis"
XP_053611673.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053612333.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053607372.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_053610419.1	5	Reactome: R-HSA-1834941;Reactome: R-HSA-3134975;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-3249367	"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"STAT6-mediated induction of chemokines"
XP_053615751.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_053612751.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053611717.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971	"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation"
XP_053602407.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053616772.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-381183	"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_053601620.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053620605.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053623506.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053618775.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_053599725.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_053618898.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053619353.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053618981.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053604097.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053607883.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053602939.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053607356.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
XP_053620213.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1"
XP_053600752.1	7	KEGG: 00220+3.5.3.1;MetaCyc: PWY-31;KEGG: 00330+3.5.3.1;MetaCyc: PWY-6922;MetaCyc: PWY-46;MetaCyc: PWY-4984;Reactome: R-HSA-70635	"Arginine biosynthesis";"Canavanine degradation";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Putrescine biosynthesis III";"Urea cycle";"Urea cycle"
XP_053622952.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_053608555.1	9	KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-8052;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-6351	"Inositol phosphate metabolism";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_053625296.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053604384.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053620585.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_053621193.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053605317.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-69091	"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Polymerase switching"
XP_053602317.1	5	Reactome: R-HSA-73817;MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6277	"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_053601351.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053602571.1	56	Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-1234176	"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"UCH proteinases";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_053607509.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_053612073.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_053615784.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053610636.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_053613535.1	7	MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500	"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle"
XP_053611544.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053623357.1	57	Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-6798695;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346	"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Separation of Sister Chromatids";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Neutrophil degranulation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Neddylation";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis"
XP_053601850.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053618451.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053601476.1	22	MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7053;MetaCyc: PWY-5353;MetaCyc: PWY-6598;MetaCyc: PWY-7049;MetaCyc: PWY-7592;MetaCyc: PWY-7727;MetaCyc: PWY-7606;MetaCyc: PWY-7725;MetaCyc: PWY-7728;MetaCyc: PWY-6433;MetaCyc: PWY-6958;MetaCyc: PWY-7035;MetaCyc: PWY-7726;MetaCyc: PWY-5080;MetaCyc: PWY-7619;KEGG: 00062+4.2.1.134;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(9Z)-tricosene biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs"
XP_053620321.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_053610417.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3249367;Reactome: R-HSA-3134975;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619	"Neutrophil degranulation";"STAT6-mediated induction of chemokines";"Regulation of innate immune responses to cytosolic DNA";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN"
XP_053616410.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_053612136.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053609599.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053611719.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971	"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation"
XP_053600649.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053604961.1	4	Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829	"CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_053625880.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053602409.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053610252.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_053622880.1	33	Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-3232142;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-4551638	"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"SUMOylation of ubiquitinylation proteins";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Transcriptional regulation by small RNAs";"snRNP Assembly";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins"
XP_053621795.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_053612946.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053621254.1	5	Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20;Reactome: R-HSA-6798695;Reactome: R-HSA-1482883	"Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism";"Neutrophil degranulation";"Acyl chain remodeling of DAG and TAG"
XP_053625525.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053606925.1	31	MetaCyc: PWY-7746;Reactome: R-HSA-163765;MetaCyc: PWY-5994;MetaCyc: PWYG-321;MetaCyc: PWY-5366;MetaCyc: PWY-8047;MetaCyc: PWY-5966-1;MetaCyc: PWY-5973;Reactome: R-HSA-75105;Reactome: R-HSA-199220;MetaCyc: PWY-5989;MetaCyc: PWY-6799;MetaCyc: PWY-4381;MetaCyc: PWY-7663;MetaCyc: PWY-5142;MetaCyc: PWY-7388;MetaCyc: PWY-7723;MetaCyc: PWY-6519;MetaCyc: PWY-8049;MetaCyc: PWY-7664;MetaCyc: PWY-6113;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168;MetaCyc: PWY-5971;MetaCyc: PWY-7858;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-8012;MetaCyc: PWY-5367	"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"";"Palmitoleate biosynthesis II (plants and bacteria)";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Cis-vaccenate biosynthesis";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Bacterial bioluminescence";"8-amino-7-oxononanoate biosynthesis I";"Pederin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Superpathway of mycolate biosynthesis";"Biotin metabolism";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mupirocin biosynthesis";"Petroselinate biosynthesis"
XP_053608995.1	3	Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053608707.1	56	Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-68827	"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex"
XP_053603841.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053606564.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053604099.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053615913.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053612913.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_053599683.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_053600197.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053607153.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_053622105.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053625043.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053625362.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053618815.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_053606394.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053624254.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_053624795.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_053603314.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_053624907.1	3	KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_053623323.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053625016.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053607966.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_053621849.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053606272.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_053618160.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053608120.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_053603865.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053601099.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_053609231.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053613358.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_053619290.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053619329.1	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
XP_053605251.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053609204.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5689880	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Ub-specific processing proteases"
XP_053619172.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_053601961.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053608049.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_053620093.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_053604385.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053603450.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053607413.1	2	Reactome: R-HSA-73621;Reactome: R-HSA-500753	"Pyrimidine catabolism";"Pyrimidine biosynthesis"
XP_053623107.1	12	Reactome: R-HSA-2565942;Reactome: R-HSA-381038;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-2132295	"Regulation of PLK1 Activity at G2/M Transition";"XBP1(S) activates chaperone genes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation"
XP_053619559.1	6	KEGG: 00520+5.4.2.3;Reactome: R-HSA-446210;MetaCyc: PWY-6749;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.10;MetaCyc: PWY-5514	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_053613243.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_053606408.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_053625756.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_053620584.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_053608266.1	6	Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788	"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling"
XP_053609748.1	5	MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+6.3.1.20;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382	"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_053607836.1	5	Reactome: R-HSA-9630222;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-9630221	"Defective NTHL1 substrate binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate processing"
XP_053605242.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053600163.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053607446.1	10	MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-7559	"Glutathione-mediated detoxification II";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway"
XP_053608491.1	56	Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764	"Degradation of GLI1 by the proteasome";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Separation of Sister Chromatids";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling"
XP_053617574.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_053618430.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160	"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions"
XP_053616952.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053600170.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053626060.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053614425.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053612659.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053608554.1	9	Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-8052	"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis"
XP_053621169.1	5	Reactome: R-HSA-75109;KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20;Reactome: R-HSA-6798695;Reactome: R-HSA-1482883	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis";"Neutrophil degranulation";"Acyl chain remodeling of DAG and TAG"
XP_053608634.1	16	Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-176408	"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase"
XP_053603003.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053618840.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_053604831.1	3	Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2	"Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism"
XP_053599724.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_053618774.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_053602230.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_053603398.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053610157.1	3	KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347	"Methane metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis"
XP_053625772.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_053603161.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053616150.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053610889.1	58	Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-6798695;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-5689901;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346	"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Metalloprotease DUBs";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Degradation of DVL";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis"
XP_053615386.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053618083.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_053612386.1	18	KEGG: 00680+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00270+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-1622;MetaCyc: PWY-5392;Reactome: R-HSA-70263;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-561;KEGG: 00630+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-5913	"Methane metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)"
XP_053619416.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053625834.1	3	Reactome: R-HSA-5689877;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395	"Josephin domain DUBs";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER"
XP_053623527.1	27	Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690	"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events"
XP_053599996.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053607295.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_053601910.1	7	Reactome: R-HSA-375165;Reactome: R-HSA-6798695;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-445095	"NCAM signaling for neurite out-growth";"Neutrophil degranulation";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins"
XP_053620631.1	11	Reactome: R-HSA-72163;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-2173796;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695	"mRNA Splicing - Major Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_053599738.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_053607222.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053613477.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053619443.1	9	KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52	"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Other glycan degradation"
XP_053600028.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053604101.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053605791.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053617643.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053611561.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_053601342.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_053625131.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053613448.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_053599556.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_053609205.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5689880;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_053610326.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053609819.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_053614391.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053621058.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_053617616.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053600486.1	14	KEGG: 00280+2.6.1.42;MetaCyc: PWY-5057;MetaCyc: PWY-5108;MetaCyc: PWY-7767;Reactome: R-HSA-70895;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5078;MetaCyc: PWY-5104;KEGG: 00270+2.6.1.42;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5103;MetaCyc: PWY-5076;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5101	"Valine, leucine and isoleucine degradation";"L-valine degradation II";"L-isoleucine biosynthesis V";"L-leucine degradation IV (Stickland reaction)";"Branched-chain amino acid catabolism";"Pantothenate and CoA biosynthesis";"L-isoleucine degradation II";"L-isoleucine biosynthesis IV";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis III";"L-leucine degradation III";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis II"
XP_053618814.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_053622104.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053606395.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053608392.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_053624794.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_053616043.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053625941.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_053600741.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450385	"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_053618102.1	2	Reactome: R-HSA-389397;Reactome: R-HSA-416476	"Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events"
XP_053608325.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053612537.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053618365.1	56	Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978	"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_053612657.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053613824.1	56	Reactome: R-HSA-174113;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880	"SCF-beta-TrCP mediated degradation of Emi1";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Neddylation";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Separation of Sister Chromatids";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases"
XP_053601070.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588	"HCMV Late Events";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_053602670.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053601330.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053609563.1	3	Reactome: R-HSA-140837;Reactome: R-HSA-111471;Reactome: R-HSA-9645722	"Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"
XP_053609021.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_053619523.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_053611057.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053621794.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68949	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin"
XP_053607106.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053625524.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053606924.1	31	Reactome: R-HSA-199220;MetaCyc: PWY-5989;MetaCyc: PWY-5966-1;MetaCyc: PWY-5973;Reactome: R-HSA-75105;MetaCyc: PWY-4381;MetaCyc: PWY-7663;MetaCyc: PWY-6799;Reactome: R-HSA-163765;MetaCyc: PWY-5994;MetaCyc: PWY-7746;MetaCyc: PWY-8047;MetaCyc: PWYG-321;MetaCyc: PWY-5366;MetaCyc: PWY-5971;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168;MetaCyc: PWY-8012;MetaCyc: PWY-5367;MetaCyc: PWY-5147;MetaCyc: PWY-7858;MetaCyc: PWY-6282;Reactome: R-HSA-9029558;MetaCyc: PWY-7723;MetaCyc: PWY-6519;MetaCyc: PWY-8049;MetaCyc: PWY-5142;MetaCyc: PWY-7388;MetaCyc: PWY-7664;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113	"Vitamin B5 (pantothenate) metabolism";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Cis-vaccenate biosynthesis";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"Bryostatin biosynthesis";"";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mupirocin biosynthesis";"Petroselinate biosynthesis";"Oleate biosynthesis I (plants)";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Bacterial bioluminescence";"8-amino-7-oxononanoate biosynthesis I";"Pederin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Oleate biosynthesis IV (anaerobic)";"Biotin metabolism";"Superpathway of mycolate biosynthesis"
XP_053615474.1	13	MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5537;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5	"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism"
XP_053608994.1	3	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions"
XP_053610159.1	3	KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347	"Glycine, serine and threonine metabolism";"Methane metabolism";"Serine biosynthesis"
XP_053624167.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053604070.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053607015.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_053599572.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_053618341.1	6	Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_053618522.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053603405.1	5	Reactome: R-HSA-5696400;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135	"Dual Incision in GG-NER";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER"
XP_053601101.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_053606796.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_053602285.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_053619999.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_053600596.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053621926.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_053605285.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids"
XP_053611168.1	8	Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5;MetaCyc: PWY-6556;KEGG: 00240+3.5.4.5;MetaCyc: PWY-7181;MetaCyc: PWY-7199;Reactome: R-HSA-6798695;MetaCyc: PWY-7193	"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine deoxyribonucleosides salvage";"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage I"
XP_053603716.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_053604063.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053614561.1	6	KEGG: 00190+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980	"Oxidative phosphorylation";"Cristae formation";"Mitochondrial protein import";"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"ATP biosynthesis"
XP_053614023.1	4	Reactome: R-HSA-9020702;Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-937039	"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"IRAK1 recruits IKK complex"
XP_053623529.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053613479.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053603743.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053619248.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_053618766.1	13	Reactome: R-HSA-2871809;Reactome: R-HSA-139853;Reactome: R-HSA-381676;Reactome: R-HSA-114508;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-422356;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921	"FCERI mediated Ca+2 mobilization";"Elevation of cytosolic Ca2+ levels";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Effects of PIP2 hydrolysis";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"Regulation of insulin secretion";"Ion homeostasis";"VEGFR2 mediated cell proliferation"
XP_053603622.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053601039.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053609291.1	5	Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-427413;KEGG: 00270+2.1.1.37	"SUMOylation of DNA methylation proteins";"DNA methylation";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"Cysteine and methionine metabolism"
XP_053601348.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557	"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis"
XP_053611884.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053614305.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053614162.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_053604122.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053612779.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_053617701.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053615250.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_053607989.1	10	Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779	"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_053604379.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053613832.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053620797.1	3	KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048	"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG"
XP_053611960.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053601920.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-189451;MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.24	"Neutrophil degranulation";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism"
XP_053620590.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053605416.1	4	KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate";"Glycerol degradation I";"Glycerolipid metabolism"
XP_053608398.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_053625747.1	12	Reactome: R-HSA-6804756;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-6796648	"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes"
XP_053623667.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053611706.1	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_053625540.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053600603.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-8866654;Reactome: R-HSA-2672351	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins";"Stimuli-sensing channels"
XP_053608161.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_053606301.1	27	Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-168325	"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis"
XP_053621336.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_053614706.1	34	Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-3232142;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-9639288;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-159231	"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"SUMOylation of ubiquitinylation proteins";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Amino acids regulate mTORC1";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_053621076.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053617856.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_053614415.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_053613518.1	7	KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2	"Arginine biosynthesis";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism"
XP_053609659.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053609539.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053610936.1	10	Reactome: R-HSA-611105;Reactome: R-HSA-5628897;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-111463;Reactome: R-HSA-2151201	"Respiratory electron transport";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs";"Transcriptional activation of mitochondrial biogenesis"
XP_053623004.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053613430.1	33	Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-68877;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4615885	"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Mitotic Prometaphase";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins"
XP_053609002.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_053618528.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_053608568.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053605306.1	6	Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_053621589.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits"
XP_053608145.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_053606142.1	3	Reactome: R-HSA-3065676;Reactome: R-HSA-3065678;Reactome: R-HSA-983168	"SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053603634.1	3	KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963;Reactome: R-HSA-947581	"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_053620480.1	5	KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22	"Sphingolipid metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_053609971.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_053604502.1	8	Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-9627069;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-111463	"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"Regulation of the apoptosome activity";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs"
XP_053623031.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053613226.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_053619867.1	5	KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-7761;MetaCyc: PWY-5381;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism"
XP_053603266.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053608618.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_053611851.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053625532.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053599866.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053625652.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053608450.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_053608935.1	4	Reactome: R-HSA-5358493;Reactome: R-HSA-8849175;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Threonine catabolism";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_053603628.1	3	MetaCyc: PWY-5963;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9	"Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_053612748.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361	"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_053624052.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_053607423.1	5	KEGG: 00240+3.6.1.6;MetaCyc: PWY-7185;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6;Reactome: R-HSA-6798695	"Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Neutrophil degranulation"
XP_053617463.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events"
XP_053621735.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053618654.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053605277.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053618534.1	9	Reactome: R-HSA-6782315;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"tRNA modification in the nucleus and cytosol";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_053605639.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_053618216.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_053602559.1	5	KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661	"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation"
XP_053601379.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053612777.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_053620861.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_053606402.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053603612.1	4	Reactome: R-HSA-198693;Reactome: R-HSA-9614399;Reactome: R-HSA-9615017;Reactome: R-HSA-5674400	"AKT phosphorylates targets in the nucleus";"Regulation of localization of FOXO transcription factors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_053614181.1	7	Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629	"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
XP_053611350.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053615777.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_053621607.1	6	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Neutrophil degranulation"
XP_053608622.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_053618662.1	9	KEGG: 00130+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00960+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00401+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00950+2.6.1.5	"Ubiquinone and other terpenoid-quinone biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Tyrosine catabolism";"Novobiocin biosynthesis";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis"
XP_053625420.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053623519.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053619285.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_053604377.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_053614013.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053624064.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053622749.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828	"MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis"
XP_053623669.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053614608.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_053600949.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-5981;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51	"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism"
XP_053625749.1	12	Reactome: R-HSA-6804756;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167246	"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript"
XP_053618512.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053610406.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_053607025.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053616515.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053599740.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_053609474.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_053619513.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_053613341.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-2132295	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation"
XP_053624780.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_053605061.1	8	KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1	"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Starch and sucrose metabolism"
XP_053621133.1	5	Reactome: R-HSA-171007;Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-4420097	"p38MAPK events";"DSCAM interactions";"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway"
XP_053601793.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-975957	"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053625236.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_053608315.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053625822.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053603392.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-428930	"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor"
XP_053611608.1	4	Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_053607543.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-198323;Reactome: R-HSA-8854214	"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"Inhibition of TSC complex formation by PKB";"Macroautophagy";"TP53 Regulates Metabolic Genes";"AKT phosphorylates targets in the cytosol";"TBC/RABGAPs"
XP_053613814.1	13	MetaCyc: PWY-2201;KEGG: 00720+6.3.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-5030;MetaCyc: PWY-3841;KEGG: 00670+6.3.4.3;Reactome: R-HSA-196757;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-2161;MetaCyc: PWY-7909;KEGG: 00720+1.5.1.5+3.5.4.9	"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"L-histidine degradation III";"Folate transformations II (plants)";"One carbon pool by folate";"Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate polyglutamylation";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes"
XP_053608980.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7	"Betanidin degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis"
XP_053609657.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053618824.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_053601206.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_053602103.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_053607516.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation"
XP_053607234.1	25	Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-9009391;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-420092;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-418555;Reactome: R-HSA-4086398;Reactome: R-HSA-418592;Reactome: R-HSA-392851;Reactome: R-HSA-400042;Reactome: R-HSA-381771;Reactome: R-HSA-392170;Reactome: R-HSA-500657;Reactome: R-HSA-6814122	"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Extra-nuclear estrogen signaling";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"Glucagon-type ligand receptors";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"G-protein activation";"G alpha (s) signalling events";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 1";"Prostacyclin signalling through prostacyclin receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"ADP signalling through P2Y purinoceptor 12";"Presynaptic function of Kainate receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053600978.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053603325.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053600807.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053625778.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5626467	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs"
XP_053624133.1	3	KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336	"Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_053619869.1	5	MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653	"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_053599732.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_053614588.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_053614154.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_053610316.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053612205.1	13	KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid metabolism";"CS/DS degradation";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis"
XP_053613485.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053607666.1	2	Reactome: R-HSA-446199;KEGG: 00510+3.6.1.43	"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis"
XP_053611046.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053622007.1	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_053615205.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053624497.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053619791.1	13	KEGG: 00720+4.2.1.2;KEGG: 00620+4.2.1.2;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-561;MetaCyc: PWY-7254;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-6728	"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle"
XP_053604118.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053611013.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053599983.1	8	MetaCyc: PWY-6611;Reactome: R-HSA-5683826;MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;Reactome: R-HSA-74217	"Adenine and adenosine salvage V";"Surfactant metabolism";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine salvage"
XP_053620950.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_053605637.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_053607228.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053603372.1	5	Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex"
XP_053604084.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053619027.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053611553.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_053611633.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053613200.1	3	Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45;KEGG: 00511+3.2.1.45	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Other glycan degradation"
XP_053616258.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053624121.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_053625936.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053606536.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053602684.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_053625798.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053606214.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_053608347.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053620196.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053616983.1	3	KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_053625081.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_053622146.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053622081.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053599641.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053609158.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins"
XP_053623582.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_053615164.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053624477.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053622113.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Formation of a pool of free 40S subunits"
XP_053610532.1	9	Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-5674135;Reactome: R-HSA-380972;Reactome: R-HSA-165159	"Neutrophil degranulation";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"MAP2K and MAPK activation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling"
XP_053619114.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053610652.1	8	MetaCyc: PWY-4661;KEGG: 00521+5.5.1.4;Reactome: R-HSA-1855183;MetaCyc: PWY-6664;KEGG: 00562+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-6372;MetaCyc: PWY-6580	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Di-myo-inositol phosphate biosynthesis";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol biosynthesis I (bacteria)"
XP_053623890.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053615360.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053607340.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_053617789.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053624243.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053606469.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053611720.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825	"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis"
XP_053615797.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_053601567.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_053621477.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053615882.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053620779.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_053607928.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053618609.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053601084.1	5	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_053617535.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7602	"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_053604051.1	6	Reactome: R-HSA-73817;MetaCyc: PWY-7234;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123;MetaCyc: PWY-6124;KEGG: 00230+3.5.4.10+2.1.2.3	"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism"
XP_053623602.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053605651.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis"
XP_053607072.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs"
XP_053599958.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_053612033.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053602531.1	11	Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;Reactome: R-HSA-163680	"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Human immunodeficiency virus 1 infection";"FOXO-mediated transcription of cell death genes";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"AMPK inhibits chREBP transcriptional activation activity"
XP_053601906.1	7	Reactome: R-HSA-6807878;Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6798695;Reactome: R-HSA-5673001	"COPI-mediated anterograde transport";"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"Neutrophil degranulation";"RAF/MAP kinase cascade"
XP_053601773.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_053624501.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053603509.1	3	Reactome: R-HSA-6783310;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Fanconi Anemia Pathway";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053617490.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053624512.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053621096.1	6	MetaCyc: PWY-6922;MetaCyc: PWY-3341;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981	"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)"
XP_053614993.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_053607404.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053600151.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053600862.1	4	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_053599598.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_053607694.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053619930.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053608349.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053622062.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_053622343.1	5	Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3	"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)"
XP_053609991.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053607841.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053623561.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053619344.1	14	Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-4302;KEGG: 00190+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-7279;MetaCyc: PWY-6728;Reactome: R-HSA-611105;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1	"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)"
XP_053606094.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-72187	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"mRNA 3'-end processing"
XP_053624479.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053608024.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053615845.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053613058.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_053620819.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_053620205.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053613926.1	12	Reactome: R-HSA-76071;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73762;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053610420.1	5	Reactome: R-HSA-3249367;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-1834941;Reactome: R-HSA-3134975	"STAT6-mediated induction of chemokines";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA"
XP_053601569.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053603153.1	7	MetaCyc: PWY-6724;MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;Reactome: R-HSA-6798695;MetaCyc: PWY-7238	"Starch degradation II";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Starch and sucrose metabolism";"Neutrophil degranulation";"Sucrose biosynthesis II"
XP_053607110.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_053605821.1	9	MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-6142	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_053618607.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053614260.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_053615152.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053620570.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_053620777.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_053619132.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053613255.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053620008.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_053613794.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_053610236.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053611993.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053606387.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-164378	"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling"
XP_053600558.1	3	Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394	"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER"
XP_053625406.1	11	KEGG: 00770+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7206;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00760+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00740+3.6.1.9	"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Starch and sucrose metabolism";"Tunicamycin biosynthesis";"Riboflavin metabolism"
XP_053600638.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_053600184.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_053600915.1	5	KEGG: 00230+2.7.4.10;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_053603280.1	1	Reactome: R-HSA-419771	"Opsins"
XP_053601627.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_053625157.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_053605690.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5469	"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Sesamin biosynthesis"
XP_053611667.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053602400.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_053602690.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053620386.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_053624518.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053624955.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_053619651.1	19	KEGG: 00983+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7176;MetaCyc: PWY-7226;Reactome: R-HSA-380320;MetaCyc: PWY-7222;Reactome: R-HSA-380270;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7227;MetaCyc: PWY-7197;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7224	"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Recruitment of NuMA to mitotic centrosomes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of mitotic centrosome proteins and complexes";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage"
XP_053619531.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_053621774.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_053614004.1	6	MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7290	"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_053608509.1	13	KEGG: 00620+4.2.1.2;KEGG: 00720+4.2.1.2;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6969;MetaCyc: PWY-8086;MetaCyc: PWY-5392;MetaCyc: PWY-7254;MetaCyc: PWY-561;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-5913	"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)"
XP_053617376.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_053612494.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_053622241.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_053625241.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053599964.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_053610801.1	42	KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6435;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6945;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7007;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-5177;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-7094;KEGG: 00623+1.1.1.35;MetaCyc: PWY-5136;MetaCyc: PWY-6944;MetaCyc: PWY-6583;MetaCyc: PWY-7654;MetaCyc: PWY-1361;MetaCyc: PWY-5109;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-7216;MetaCyc: PWY-5138;MetaCyc: PWY-5789;MetaCyc: PWY-7401;MetaCyc: PWY-7778;KEGG: 00410+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6946;MetaCyc: PWY-7779	"Benzoate degradation";"Butanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Limonene and pinene degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Aminobenzoate degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Phenylalanine metabolism";"Methyl ketone biosynthesis (engineered)";"Tryptophan metabolism";"Fatty acid degradation";"Propanoate metabolism";"Fatty acid elongation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Glutaryl-coa degradation";"Caprolactam degradation";"Pyruvate fermentation to hexanol (engineered)";"Lysine degradation";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid salvage";"Toluene degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Androstenedione degradation";"Pyruvate fermentation to butanol I";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Benzoyl-coa degradation I (aerobic)";"Fermentation to 2-methylbutanoate";"Geraniol degradation";"Spodoptera littoralis pheromone biosynthesis";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"2-methylpropene degradation";"beta-Alanine metabolism";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Methyl tert-butyl ether degradation"
XP_053614986.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053599592.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_053604090.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053604653.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053609882.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_053624226.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_053625503.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053607555.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053622068.1	6	MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_053620291.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_053616419.1	3	Reactome: R-HSA-2206282;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50	"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation";"Glycosaminoglycan degradation"
XP_053609797.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473	"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint"
XP_053613499.1	7	Reactome: R-HSA-5628897;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500	"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle"
XP_053609905.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053613052.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053608356.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053620466.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053612551.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053617207.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_053602053.1	7	MetaCyc: PWY-6277;MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6122	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_053606647.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053605053.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_053611710.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053609360.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053617352.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-2206305;KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720;Reactome: R-HSA-2022857	"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D";"Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis";"Keratan sulfate degradation"
XP_053622123.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_053606238.1	4	Reactome: R-HSA-1971475;KEGG: 00532+2.4.2.26;MetaCyc: PWY-6557;KEGG: 00534+2.4.2.26	"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_053625123.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade"
XP_053602985.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053619299.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053619124.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053620971.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_053602310.1	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
XP_053623162.1	19	Reactome: R-HSA-432142;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-3000484;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8964038;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-8963888	"Platelet sensitization by LDL";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"Scavenging by Class F Receptors";"LDL remodeling";"Regulation of TLR by endogenous ligand";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL clearance";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"VLDL clearance";"Clathrin-mediated endocytosis";"VLDL assembly";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"Chylomicron assembly"
XP_053612584.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_053617981.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053602802.1	6	KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;Reactome: R-HSA-9033241	"Tryptophan metabolism";"Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Peroxisomal protein import"
XP_053616636.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053619948.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053613803.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_053624832.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_053617775.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053608040.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053624111.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053603119.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_053604627.1	6	KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-2221;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17	"Caprolactam degradation";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism"
XP_053620539.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_053622683.1	6	Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-975578	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_053624774.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_053621430.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_053625683.1	10	MetaCyc: PWY-4321;KEGG: 00410+2.6.1.19;KEGG: 00650+2.6.1.19;Reactome: R-HSA-916853;KEGG: 00250+2.6.1.19;MetaCyc: PWY-5022;MetaCyc: PWY-6536;MetaCyc: PWY-6535;KEGG: 00640+2.6.1.19;MetaCyc: PWY-6537	"L-glutamate degradation IV";"beta-Alanine metabolism";"Butanoate metabolism";"Degradation of GABA";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation V";"4-aminobutanoate degradation III";"4-aminobutanoate degradation I";"Propanoate metabolism";"4-aminobutanoate degradation II"
XP_053619017.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_053608755.1	4	KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism"
XP_053609373.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_053606752.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_053608294.1	6	MetaCyc: PWY-6118;Reactome: R-HSA-163560;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952	"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Glycerol degradation I";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation"
XP_053605027.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_053608129.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-975871;Reactome: R-HSA-166058;Reactome: R-HSA-975138	"Complex I biogenesis";"MyD88 cascade initiated on plasma membrane";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation"
XP_053625265.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053611986.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053618794.1	14	KEGG: 00564+3.1.3.4;MetaCyc: PWY-8051;Reactome: R-HSA-1483213;Reactome: R-HSA-4419969;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-8052;KEGG: 00600+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-1483191	"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Synthesis of PE";"Depolymerisation of the Nuclear Lamina";"Ether lipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"2-arachidonoylglycerol biosynthesis";"Sphingolipid metabolism";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PC"
XP_053607338.1	10	Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-917729;Reactome: R-HSA-9635644;Reactome: R-HSA-432720;Reactome: R-HSA-6807004;Reactome: R-HSA-5689880;Reactome: R-HSA-8856825;Reactome: R-HSA-9636383;Reactome: R-HSA-182971	"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Inhibition of membrane repair";"Lysosome Vesicle Biogenesis";"Negative regulation of MET activity";"Ub-specific processing proteases";"Cargo recognition for clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"EGFR downregulation"
XP_053616252.1	14	KEGG: 00650+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-7254;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690;Reactome: R-HSA-611105;MetaCyc: PWY-6728;MetaCyc: PWY-7279;KEGG: 00720+1.3.5.1;Reactome: R-HSA-71403;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-4302	"Butanoate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Respiratory electron transport";"Methylaspartate cycle";"Aerobic respiration II (cytochrome c) (yeast)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Oxidative phosphorylation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration III (alternative oxidase pathway)"
XP_053611669.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053611472.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_053604823.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053621900.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_053625792.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_053608507.1	13	KEGG: 00720+4.2.1.2;KEGG: 00620+4.2.1.2;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6969;MetaCyc: PWY-8086;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-561;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-5913	"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)"
XP_053605132.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053617173.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053617484.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053606764.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053600256.1	4	MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661;MetaCyc: PWY-7382	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_053609861.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_053623154.1	11	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;KEGG: 04926+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3270619	"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Relaxin signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"IRF3-mediated induction of type I IFN"
XP_053623588.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_053623350.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_053604210.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053605811.1	18	Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;MetaCyc: PWY-6803	"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Synthesis of PA";"Linoleic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing"
XP_053616996.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053613916.1	2	Reactome: R-HSA-429958;Reactome: R-HSA-390471	"mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053614870.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053615271.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053606649.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053608153.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053619297.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053614744.1	7	Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-2559586;Reactome: R-HSA-171306;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-110329	"Meiotic synapsis";"Cleavage of the damaged purine";"DNA Damage/Telomere Stress Induced Senescence";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine"
XP_053623046.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053607707.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053624766.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_053602344.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053607922.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053618058.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053615888.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053615991.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053612991.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053610131.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_053623608.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_053603117.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_053604629.1	6	KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17	"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Caprolactam degradation"
XP_053623498.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053611863.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053621814.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_053610104.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_053624522.1	14	MetaCyc: PWY-8004;MetaCyc: PWY-6142;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7124;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-6886;MetaCyc: PWY-2221;MetaCyc: PWY-1622;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7218;MetaCyc: PWY-5723	"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt"
XP_053619019.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053618167.1	10	MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6397;MetaCyc: PWY-6317;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-7328	"D-galactose detoxification";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis"
XP_053605029.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_053599952.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_053615069.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053618437.1	17	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Formation of a pool of free 40S subunits"
XP_053624898.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_053615246.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_053606225.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053624775.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_053608222.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053602873.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053603212.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_053612739.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053618847.1	6	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062;Reactome: R-HSA-5684045;Reactome: R-HSA-2046105;Reactome: R-HSA-390247;Reactome: R-HSA-2046106	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Linoleic acid (LA) metabolism";"Beta-oxidation of very long chain fatty acids";"alpha-linolenic acid (ALA) metabolism"
XP_053599812.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-2022854;Reactome: R-HSA-5083627	"O-linked glycosylation";"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_053602648.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041	"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis"
XP_053616683.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053625264.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053622636.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603	"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine"
XP_053623100.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_053611782.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-442982	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_053609548.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_053604496.1	4	MetaCyc: PWY-7437;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847	"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"Other types of O-glycan biosynthesis";"HATs acetylate histones"
XP_053619125.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053608303.1	6	MetaCyc: PWY-6952;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;MetaCyc: PWY-4261;Reactome: R-HSA-163560	"Glycerophosphodiester degradation";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Triglyceride catabolism"
XP_053602006.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053605006.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053624036.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_053614208.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053624376.1	4	Reactome: R-HSA-2162123;Reactome: R-HSA-6798695;Reactome: R-HSA-499943;KEGG: 00590+5.3.99.3	"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Neutrophil degranulation";"Interconversion of nucleotide di- and triphosphates";"Arachidonic acid metabolism"
XP_053609141.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_053619990.1	5	Reactome: R-HSA-73621;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3	"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism"
XP_053625419.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053599538.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_053607554.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053601917.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_053601606.1	4	MetaCyc: PWY-7250;Reactome: R-HSA-1362409;Reactome: R-HSA-947581;KEGG: 00730+2.8.1.7	"[2Fe-2S] iron-sulfur cluster biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis";"Thiamine metabolism"
XP_053610976.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053613383.1	5	KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)"
XP_053609904.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053617518.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5625740	"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs"
XP_053617430.1	27	Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-4085377	"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"snRNP Assembly";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins"
XP_053606001.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_053616241.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053607491.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053607628.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_053599524.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_053601048.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053602237.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053607601.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053612422.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053614143.1	13	Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916	"Keratan sulfate degradation";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"CS/DS degradation";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation"
XP_053602462.1	5	KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41	"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism"
XP_053605462.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053621775.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_053614005.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053624954.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_053600318.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_053621898.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_053612495.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_053625572.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-1912420	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi"
XP_053599965.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_053621352.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053608781.1	9	MetaCyc: PWY-8086;MetaCyc: PWY-6142;Reactome: R-HSA-196780;Reactome: R-HSA-70263;Reactome: R-HSA-3371599;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;KEGG: 00720+6.4.1.1	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Biotin transport and metabolism";"Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Carbon fixation pathways in prokaryotes"
XP_053609931.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_053604079.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053607726.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_053618439.1	16	Reactome: R-HSA-1234176;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-983168;Reactome: R-HSA-167287;Reactome: R-HSA-9010553;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-180585;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-8951664;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-6796648	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Vif-mediated degradation of APOBEC3G";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Neddylation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes"
XP_053611346.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_053612418.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053612737.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053612650.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_053612530.1	20	MetaCyc: PWY-735;MetaCyc: PWY-7574;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-6920;MetaCyc: PWY-7854;MetaCyc: PWY-7007;Reactome: R-HSA-9033241;MetaCyc: PWY-7291	"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)"
XP_053606741.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053615418.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053609401.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053601077.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053609691.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_053619468.1	14	Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-5687128	"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling"
XP_053607562.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_053614745.1	5	Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571	"2-LTR circle formation";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)"
XP_053603459.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_053610482.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053599756.1	10	Reactome: R-HSA-2565942;Reactome: R-HSA-5696395;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-3108214;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-5696394	"Regulation of PLK1 Activity at G2/M Transition";"Formation of Incision Complex in GG-NER";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"SUMOylation of DNA damage response and repair proteins";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"DNA Damage Recognition in GG-NER"
XP_053612093.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053601721.1	6	Reactome: R-HSA-6781823;Reactome: R-HSA-6798695;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781827	"Formation of TC-NER Pre-Incision Complex";"Neutrophil degranulation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_053619388.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_053605591.1	7	Reactome: R-HSA-204174;Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)"
XP_053602345.1	4	MetaCyc: PWY-7285;MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6782861	"Methylwyosine biosynthesis";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_053606366.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053603025.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_053611899.1	27	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-8851708;Reactome: R-HSA-167158;Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72165;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-975956;Reactome: R-HSA-6803529;Reactome: R-HSA-72187	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"Signaling by FGFR2 IIIa TM";"Formation of the HIV-1 Early Elongation Complex";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Minor Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"FGFR2 alternative splicing";"mRNA 3'-end processing"
XP_053603516.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_053611745.1	10	MetaCyc: PWY-5030;MetaCyc: PWY-7909;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-5497;MetaCyc: PWY-6613;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;Reactome: R-HSA-196757	"L-histidine degradation III";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines"
XP_053625738.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053600796.1	6	Reactome: R-HSA-1442490;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814	"Collagen degradation";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes"
XP_053623155.1	11	KEGG: 04926+2.7.11.1;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"IRF3-mediated induction of type I IFN";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"E3 ubiquitin ligases ubiquitinate target proteins";"mTOR signaling pathway"
XP_053599834.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053601919.1	5	Reactome: R-HSA-189451;Reactome: R-HSA-6798695;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;MetaCyc: PWY-5189	"Heme biosynthesis";"Neutrophil degranulation";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)"
XP_053614761.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_053614899.1	15	Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-9603505;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167152	"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"NTRK3 as a dependence receptor";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_053612321.1	4	Reactome: R-HSA-1660662;MetaCyc: PWY-6483;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23	"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism"
XP_053615308.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053615321.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053618878.1	9	Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Smooth Muscle Contraction";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation"
XP_053618616.1	56	Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-9020702	"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling"
XP_053602677.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053609763.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053599828.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053610592.1	8	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-167590;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"Nef Mediated CD8 Down-regulation";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_053624815.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053605713.1	10	Reactome: R-HSA-3214847;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-201722;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"HATs acetylate histones";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Formation of the beta-catenin:TCF transactivating complex";"Human papillomavirus infection";"Human cytomegalovirus infection";"Ub-specific processing proteases";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_053602713.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7601	"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_053603228.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_053605481.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053614346.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Unwinding of DNA";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_053619642.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053616159.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053624160.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053618643.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053616887.1	5	Reactome: R-HSA-4085001;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1660662	"Sialic acid metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"MHC class II antigen presentation";"Glycosphingolipid metabolism"
XP_053613626.1	4	Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815	"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones"
XP_053617485.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053614313.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_053608762.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053604077.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053599772.1	8	Reactome: R-HSA-6791055;Reactome: R-HSA-6791462;MetaCyc: PWY-5723;Reactome: R-HSA-71336;MetaCyc: PWY-1861;Reactome: R-HSA-8950505;Reactome: R-HSA-163754;KEGG: 00030+2.2.1.2	"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Rubisco shunt";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Pentose phosphate pathway"
XP_053606765.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_053600148.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053625740.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053601085.1	4	Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852	"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Macroautophagy"
XP_053622547.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_053603446.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_053606603.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053606493.1	13	Reactome: R-HSA-2160916;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52	"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"CS/DS degradation";"Keratan sulfate degradation";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series"
XP_053612412.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_053623848.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053619382.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053611359.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_053612579.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053615257.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_053615579.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053600334.1	4	MetaCyc: PWY-7394;MetaCyc: PWY-7849;MetaCyc: PWY-5691;KEGG: 00230+4.1.1.97	"Urate conversion to allantoin II";"Urate conversion to allantoin III";"Urate conversion to allantoin I";"Purine metabolism"
XP_053625429.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053604288.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_053623673.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053622429.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053624535.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053612086.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_053618383.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012	"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053620790.1	9	KEGG: 00790+3.5.4.16;MetaCyc: PWY-6147;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-5664;MetaCyc: PWY-7852;MetaCyc: PWY-5663;MetaCyc: PWY-6983;MetaCyc: PWY-6703	"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Preq0 biosynthesis"
XP_053612141.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053602990.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_053620597.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053609820.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_053617121.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_053611686.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053619860.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_053609585.1	14	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-380284;Reactome: R-HSA-141444;Reactome: R-HSA-380259;Reactome: R-HSA-2500257	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Loss of Nlp from mitotic centrosomes";"Resolution of Sister Chromatid Cohesion"
XP_053619006.1	19	Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888;Reactome: R-HSA-202733;Reactome: R-HSA-8856828;Reactome: R-HSA-8964046;Reactome: R-HSA-8963901;Reactome: R-HSA-8866423;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-432142;Reactome: R-HSA-3000484;Reactome: R-HSA-5686938;Reactome: R-HSA-8964041;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038	"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"Chylomicron assembly";"Cell surface interactions at the vascular wall";"Clathrin-mediated endocytosis";"VLDL clearance";"Chylomicron remodeling";"VLDL assembly";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"Platelet sensitization by LDL";"Scavenging by Class F Receptors";"Regulation of TLR by endogenous ligand";"LDL remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"LDL clearance"
XP_053600074.1	4	MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268	"Entner-Doudoroff pathway I";"Glutathione metabolism";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_053602192.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053614211.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053622983.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_053601288.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_053615165.1	13	Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-3371511;Reactome: R-HSA-9646399;Reactome: R-HSA-5362768;Reactome: R-HSA-8866654;Reactome: R-HSA-8876725;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-5689877;Reactome: R-HSA-110320;Reactome: R-HSA-532668;Reactome: R-HSA-5689896	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"HSF1 activation";"Aggrephagy";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"E3 ubiquitin ligases ubiquitinate target proteins";"Protein methylation";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"Josephin domain DUBs";"Translesion Synthesis by POLH";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Ovarian tumor domain proteases"
XP_053621655.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053615302.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053625983.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053619115.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053604871.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_053602270.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_053605759.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_053614967.1	5	KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22	"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism"
XP_053619648.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_053604085.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053617681.1	31	MetaCyc: PWY-7664;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;MetaCyc: PWY-5142;MetaCyc: PWY-7388;MetaCyc: PWY-6519;MetaCyc: PWY-7723;MetaCyc: PWY-8049;MetaCyc: PWY-7858;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-5367;MetaCyc: PWY-8012;Reactome: R-HSA-2426168;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5971;MetaCyc: PWY-5366;MetaCyc: PWYG-321;MetaCyc: PWY-8047;MetaCyc: PWY-7746;Reactome: R-HSA-163765;MetaCyc: PWY-5994;MetaCyc: PWY-6799;MetaCyc: PWY-4381;MetaCyc: PWY-7663;MetaCyc: PWY-5966-1;MetaCyc: PWY-5973;Reactome: R-HSA-75105;Reactome: R-HSA-199220;MetaCyc: PWY-5989	"Oleate biosynthesis IV (anaerobic)";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"8-amino-7-oxononanoate biosynthesis I";"Bacterial bioluminescence";"Pederin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Petroselinate biosynthesis";"Mupirocin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Cis-vaccenate biosynthesis";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Stearate biosynthesis II (bacteria and plants)"
XP_053613437.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053609739.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053618872.1	52	Reactome: R-HSA-167246;Reactome: R-HSA-76066;Reactome: R-HSA-73762;Reactome: R-HSA-1834949;Reactome: R-HSA-112382;Reactome: R-HSA-6781827;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-75955;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-76071;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-749476;Reactome: R-HSA-6782135;Reactome: R-HSA-167290;Reactome: R-HSA-167162;Reactome: R-HSA-5250924;Reactome: R-HSA-6781823;Reactome: R-HSA-73780;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-427413;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-76061;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-5617472;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-167200;Reactome: R-HSA-203927;Reactome: R-HSA-5578749;Reactome: R-HSA-5601884;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-73980;Reactome: R-HSA-75953;Reactome: R-HSA-167160	"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"Formation of RNA Pol II elongation complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Abortive And Retractive Initiation";"Dual incision in TC-NER";"Pausing and recovery of HIV elongation";"RNA Polymerase II HIV Promoter Escape";"B-WICH complex positively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Chain Elongation";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"NoRC negatively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"FGFR2 alternative splicing";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"MicroRNA (miRNA) biogenesis";"Transcriptional regulation by small RNAs";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_053612223.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053618701.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_053620671.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053613847.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_053609246.1	6	MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433	"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_053608212.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053602685.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_053625549.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053608228.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053608201.1	16	Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-69473;Reactome: R-HSA-5693571	"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HATs acetylate histones";"Estrogen-dependent gene expression";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)"
XP_053613254.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053599540.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_053610958.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_053614323.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_053605642.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_053622171.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053625171.1	44	Reactome: R-HSA-6802952;Reactome: R-HSA-74749;Reactome: R-HSA-2559582;Reactome: R-HSA-5654726;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5654727;Reactome: R-HSA-5673001;Reactome: R-HSA-456926;Reactome: R-HSA-9627069;Reactome: R-HSA-982772;Reactome: R-HSA-3371453;Reactome: R-HSA-9634638;Reactome: R-HSA-881907;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-2559585;Reactome: R-HSA-162658;Reactome: R-HSA-112409;Reactome: R-HSA-5654732;Reactome: R-HSA-8939211;Reactome: R-HSA-5668599;Reactome: R-HSA-8940973;Reactome: R-HSA-6802948;Reactome: R-HSA-170968;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-2871796;Reactome: R-HSA-5663213;Reactome: R-HSA-450341;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-5675221;Reactome: R-HSA-375165;Reactome: R-HSA-9635465;Reactome: R-HSA-198753;Reactome: R-HSA-6811558;Reactome: R-HSA-2029482;Reactome: R-HSA-1295596;Reactome: R-HSA-445144;Reactome: R-HSA-879415;Reactome: R-HSA-444257;Reactome: R-HSA-202670;Reactome: R-HSA-5674499;Reactome: R-HSA-5654733	"Signaling by BRAF and RAF fusions";"Signal attenuation";"Senescence-Associated Secretory Phenotype (SASP)";"Negative regulation of FGFR1 signaling";"mTOR signaling pathway";"Negative regulation of FGFR2 signaling";"RAF/MAP kinase cascade";"Thrombin signalling through proteinase activated receptors (PARs)";"Regulation of the apoptosome activity";"Growth hormone receptor signaling";"Regulation of HSF1-mediated heat shock response";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Gastrin-CREB signalling pathway via PKC and MAPK";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Oncogene Induced Senescence";"Golgi Cisternae Pericentriolar Stack Reorganization";"RAF-independent MAPK1/3 activation";"Negative regulation of FGFR3 signaling";"ESR-mediated signaling";"RHO GTPases Activate NADPH Oxidases";"RUNX2 regulates osteoblast differentiation";"Signaling by high-kinase activity BRAF mutants";"Frs2-mediated activation";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"FCERI mediated MAPK activation";"RHO GTPases Activate WASPs and WAVEs";"Activation of the AP-1 family of transcription factors";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"Negative regulation of MAPK pathway";"NCAM signaling for neurite out-growth";"Suppression of apoptosis";"ERK/MAPK targets";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Regulation of actin dynamics for phagocytic cup formation";"Spry regulation of FGF signaling";"Signal transduction by L1";"Advanced glycosylation endproduct receptor signaling";"RSK activation";"ERKs are inactivated";"Negative feedback regulation of MAPK pathway";"Negative regulation of FGFR4 signaling"
XP_053618626.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053599818.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627	"Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_053599676.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053624787.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_053612763.1	6	Reactome: R-HSA-5626467;Reactome: R-HSA-2173796;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"RHO GTPases activate IQGAPs";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_053600185.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_053602723.1	2	Reactome: R-HSA-1663150;Reactome: R-HSA-1660662	"The activation of arylsulfatases";"Glycosphingolipid metabolism"
XP_053619239.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053624358.1	8	MetaCyc: PWY-5049;KEGG: 00350+1.14.16.2;MetaCyc: PWY-5394;KEGG: 00950+1.14.16.2;MetaCyc: PWY-6133;MetaCyc: PWY-3581;KEGG: 00790+1.14.16.2;Reactome: R-HSA-209905	"Rosmarinic acid biosynthesis II";"Tyrosine metabolism";"Betalamic acid biosynthesis";"Isoquinoline alkaloid biosynthesis";"(S)-reticuline biosynthesis II";"(S)-reticuline biosynthesis I";"Folate biosynthesis";"Catecholamine biosynthesis"
XP_053600914.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_053615763.1	3	Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine degradation";"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_053606298.1	1	Reactome: R-HSA-1614603	"Cysteine formation from homocysteine"
XP_053623544.1	13	KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.23;Reactome: R-HSA-1660662;Reactome: R-HSA-2206308;Reactome: R-HSA-2024096;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;Reactome: R-HSA-4085001	"Sphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"MPS IV - Morquio syndrome B";"HS-GAG degradation";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Sialic acid metabolism"
XP_053609542.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053619361.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_053615577.1	52	Reactome: R-HSA-113418;Reactome: R-HSA-5601884;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-73980;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-5617472;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-76042;Reactome: R-HSA-167200;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6803529;Reactome: R-HSA-76061;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-168325;Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-5250924;Reactome: R-HSA-167162;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-6781823;Reactome: R-HSA-72203;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-76071;Reactome: R-HSA-75955;Reactome: R-HSA-73863;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-73762;Reactome: R-HSA-76066;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-1834949	"Formation of the Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"FGFR2 alternative splicing";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Viral Messenger RNA Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Formation of TC-NER Pre-Incision Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Estrogen-dependent gene expression";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Termination";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Cytosolic sensors of pathogen-associated DNA"
XP_053615311.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053608516.1	5	Reactome: R-HSA-196757;KEGG: 00670+1.5.1.20;KEGG: 00720+1.5.1.20;MetaCyc: PWY-2201;MetaCyc: PWY-3841	"Metabolism of folate and pterines";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Folate transformations II (plants)"
XP_053611357.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_053614202.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053617096.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053610665.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_053625427.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053607980.1	6	Reactome: R-HSA-1483148;MetaCyc: PWY-5668;MetaCyc: PWY-5269;KEGG: 00564+2.7.8.5;MetaCyc: PWY-7817;Reactome: R-HSA-1483166	"Synthesis of PG";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PA"
XP_053601929.1	4	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation"
XP_053604483.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053613396.1	4	KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581;MetaCyc: PWY-7887;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis"
XP_053607182.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_053619345.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053614357.1	13	MetaCyc: PWY-7709;MetaCyc: PWY-7141;MetaCyc: PWY-7102;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-7410;MetaCyc: PWY-7182;MetaCyc: PWY-7659;MetaCyc: PWY-6859;MetaCyc: PWY-5122;MetaCyc: PWY-5123;MetaCyc: PWY-6383;MetaCyc: PWY-7721	"(3R)-linalool biosynthesis";"(3S)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"Ipsdienol biosynthesis";"Linalool biosynthesis I";"Viridicatumtoxin biosynthesis";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Methyl phomopsenoate biosynthesis"
XP_053625000.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
XP_053622000.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053615844.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053608025.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053624600.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_053611202.1	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_053616343.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142	"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins"
XP_053610641.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_053601370.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_053620957.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_053614969.1	10	KEGG: 00650+2.3.3.10;KEGG: 00280+2.3.3.10;MetaCyc: PWY-6174;MetaCyc: PWY-7524;Reactome: R-HSA-1989781;MetaCyc: PWY-7391;MetaCyc: PWY-7571;KEGG: 00072+2.3.3.10;KEGG: 00900+2.3.3.10;MetaCyc: PWY-922	"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Ferrichrome A biosynthesis";"Synthesis and degradation of ketone bodies";"Terpenoid backbone biosynthesis";"Mevalonate pathway I"
XP_053605757.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_053620204.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053607743.1	4	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
XP_053615428.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_053605468.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053615401.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053611323.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053601042.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053607622.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053625453.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_053621358.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053600800.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-9609690;Reactome: R-HSA-3899300	"Regulation of TP53 Degradation";"HCMV Early Events";"SUMOylation of transcription cofactors"
XP_053614091.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_053606978.1	2	Reactome: R-HSA-6793080;Reactome: R-HSA-2151201	"rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis"
XP_053625578.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-1912420	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi"
XP_053622095.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053611220.1	9	Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)"
XP_053624622.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053600007.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_053602845.1	14	MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-6598	"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis"
XP_053618024.1	6	Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-162594;Reactome: R-HSA-5685939;Reactome: R-HSA-110362;Reactome: R-HSA-69166	"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Early Phase of HIV Life Cycle";"HDR through MMEJ (alt-NHEJ)";"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate"
XP_053614569.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053618896.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053623508.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053620279.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_053613014.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053623342.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053623063.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053619991.1	5	MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621	"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine catabolism"
XP_053624405.1	12	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-416482;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"NRAGE signals death through JNK";"Relaxin signaling pathway";"DCC mediated attractive signaling";"Rho GTPase cycle";"PI3K-Akt signaling pathway"
XP_053608780.1	9	MetaCyc: PWY-8086;MetaCyc: PWY-6142;KEGG: 00720+6.4.1.1;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599;Reactome: R-HSA-70263;Reactome: R-HSA-196780	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis";"Biotin transport and metabolism"
XP_053618349.1	20	MetaCyc: PWY-7726;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-7340;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-5136;MetaCyc: PWY-7858;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7007;MetaCyc: PWY-6920;MetaCyc: PWY-7854	"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"(5Z)-dodecenoate biosynthesis II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)"
XP_053609930.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_053609455.1	12	MetaCyc: PWY-6277;KEGG: 00230+2.1.2.2;KEGG: 00230+6.3.3.1;KEGG: 00670+2.1.2.9;Reactome: R-HSA-73817;MetaCyc: PWY-6613;MetaCyc: PWY-6121;KEGG: 00970+2.1.2.9;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6122;KEGG: 00670+2.1.2.2;Reactome: R-HSA-196780	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Purine metabolism";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"5-aminoimidazole ribonucleotide biosynthesis I";"Aminoacyl-tRNA biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"One carbon pool by folate";"Biotin transport and metabolism"
XP_053617694.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_053611436.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_053600822.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053617404.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053602176.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-111932;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736	"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"CaMK IV-mediated phosphorylation of CREB";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"RAF activation";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors"
XP_053600778.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_053621315.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053606578.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053615019.1	3	Reactome: R-HSA-3299685;KEGG: 00230+3.6.1.17;KEGG: 00240+3.6.1.17	"Detoxification of Reactive Oxygen Species";"Purine metabolism";"Pyrimidine metabolism"
XP_053607600.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053610247.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053616240.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053607490.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053624864.1	11	Reactome: R-HSA-1250196;Reactome: R-HSA-1963642;Reactome: R-HSA-1257604;Reactome: R-HSA-6785631;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-9664565	"SHC1 events in ERBB2 signaling";"PI3K events in ERBB2 signaling";"PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2 KD Mutants"
XP_053610184.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053610638.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942	"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_053610558.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_053610473.1	5	Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-450341	"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors"
XP_053625949.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
YP_009166939.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_053614436.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_053616387.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053624315.1	8	MetaCyc: PWY-5481;MetaCyc: PWY-6901;KEGG: 00270+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;KEGG: 00640+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086	"Pyruvate fermentation to (S)-lactate";"Superpathway of glucose and xylose degradation";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_053623688.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053625298.1	17	Reactome: R-HSA-69231;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-113501;Reactome: R-HSA-2559580;Reactome: R-HSA-9616222;Reactome: R-HSA-69656;Reactome: R-HSA-6804114;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-111448;Reactome: R-HSA-139915;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-8953750;Reactome: R-HSA-2173796;Reactome: R-HSA-1362277	"Cyclin D associated events in G1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Oxidative Stress Induced Senescence";"Transcriptional regulation of granulopoiesis";"Cyclin A:Cdk2-associated events at S phase entry";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"Activation of NOXA and translocation to mitochondria";"Activation of PUMA and translocation to mitochondria";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcriptional Regulation by E2F6";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by DREAM complex"
XP_053603255.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_053620523.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053599855.1	26	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-9013695;Reactome: R-HSA-3371568;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-933541;Reactome: R-HSA-9617629;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-8866907;Reactome: R-HSA-918233;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-3899300;Reactome: R-HSA-5617472;Reactome: R-HSA-3134973	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"NOTCH4 Intracellular Domain Regulates Transcription";"Attenuation phase";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"TRAF6 mediated IRF7 activation";"Regulation of FOXO transcriptional activity by acetylation";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"TRAF3-dependent IRF activation pathway";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"RORA activates gene expression";"Estrogen-dependent gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"
XP_053608497.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053612808.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_053608607.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_053621743.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053614175.1	7	Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629	"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
XP_053616232.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053611569.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_053607787.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053610460.1	5	Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-164843	"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"2-LTR circle formation"
XP_053621405.1	15	Reactome: R-HSA-6807505;Reactome: R-HSA-9018519;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-2173796;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-176034	"RNA polymerase II transcribes snRNA genes";"Estrogen-dependent gene expression";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Interactions of Tat with host cellular proteins"
XP_053607580.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053623128.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053612320.1	4	MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;Reactome: R-HSA-1660662	"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Ceramide degradation (generic)";"Glycosphingolipid metabolism"
XP_053623112.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053602360.1	3	Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857	"Digestion of dietary lipid";"Glycerolipid metabolism";"Retinol biosynthesis"
XP_053600652.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053609114.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_053608803.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053614760.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_053604527.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_053614567.1	3	Reactome: R-HSA-1660516;Reactome: R-HSA-1660517;Reactome: R-HSA-1660514	"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane"
XP_053620277.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_053616214.1	12	Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-5250924;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-73762	"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"B-WICH complex positively regulates rRNA expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RNA Polymerase I Transcription Initiation"
XP_053612138.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053616536.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_053624161.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053624852.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053614906.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs"
XP_053605373.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053625215.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_053601478.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_053613372.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_053610249.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_053624568.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053624145.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053601449.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_053609400.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053616389.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053605033.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-388844	"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
YP_009166937.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_053625947.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_053618280.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_053619604.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_053621398.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053622603.1	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_053599914.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053608052.1	7	KEGG: 00730+3.6.1.15;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7198;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7210;MetaCyc: PWY-7185	"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I"
XP_053620443.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053612504.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053625018.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053608499.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053599692.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053610335.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053613883.1	3	Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361	"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_053625137.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053599625.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053620997.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_053624935.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_053623385.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053602271.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_053605271.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053607815.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053600658.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053603916.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053620285.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_053610087.1	5	MetaCyc: PWY-7282;Reactome: R-HSA-964975;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7204;Reactome: R-HSA-6798695	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"Neutrophil degranulation"
XP_053606996.1	4	Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48	"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_053611189.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_053614210.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053608926.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053615942.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_053612811.1	18	MetaCyc: PWY-7511;Reactome: R-HSA-6796648;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;Reactome: R-HSA-8953750;Reactome: R-HSA-5693616;Reactome: R-HSA-1221632;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5689901;Reactome: R-HSA-3108214;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607	"Protein ubiquitination";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Transcriptional Regulation by E2F6";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic synapsis";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Metalloprotease DUBs";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends"
XP_053611857.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_053607364.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_053609821.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_053601744.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053609977.1	15	Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-5685939;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-5685942;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579	"Meiotic recombination";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Homologous Recombination (HRR)";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange"
XP_053610564.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053607484.1	57	Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813	"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"Neutrophil degranulation";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Separation of Sister Chromatids"
XP_053620670.1	3	Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_053618700.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_053622765.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_053613378.1	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_053600965.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053620546.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_053608255.1	9	Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_053611629.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_053601669.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053617049.1	8	MetaCyc: PWY-6611;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;Reactome: R-HSA-5683826;MetaCyc: PWY-7179;MetaCyc: PWY-6609;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1	"Adenine and adenosine salvage V";"Purine metabolism";"Neutrophil degranulation";"Surfactant metabolism";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Purine salvage";"Purine deoxyribonucleosides degradation II"
XP_053624392.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_053624994.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-170660	"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Adenylate cyclase activating pathway"
XP_053621858.1	12	Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells"
XP_053612029.1	22	MetaCyc: PWY-7728;MetaCyc: PWY-7606;MetaCyc: PWY-7049;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7724;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7619;MetaCyc: PWY-7726;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7727;MetaCyc: PWY-7592;MetaCyc: PWY-7053;MetaCyc: PWY-5353;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-6958	"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Juniperonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis I (lower eukaryotes)"
XP_053602069.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_053606307.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_053621274.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053619176.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_053625486.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_053601863.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053610394.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_053611823.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053616197.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053600812.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053622741.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_053615455.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053623661.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053614629.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053612930.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053601870.1	32	Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-8851708;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-168325;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-73776	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by FGFR2 IIIa TM";"mRNA Capping";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Viral Messenger RNA Synthesis";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape"
XP_053602991.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_053612140.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053605991.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_053599698.1	5	MetaCyc: PWY-7159;MetaCyc: PWY-5531;Reactome: R-HSA-189451;MetaCyc: PWY-7766;KEGG: 00860+4.1.1.37	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)";"Porphyrin and chlorophyll metabolism"
XP_053620791.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053625012.1	3	Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942	"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)"
XP_053602888.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163359	"PKA activation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Hedgehog 'off' state";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation"
XP_053622012.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053606276.1	33	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-3232142;Reactome: R-HSA-9648025;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-180910	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"Mitotic Prometaphase";"SUMOylation of ubiquitinylation proteins";"EML4 and NUDC in mitotic spindle formation";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs"
XP_053616843.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053617995.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053617707.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053616433.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_053617500.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_053604744.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053616678.1	7	Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938	"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)"
XP_053609297.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053625366.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053615053.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_053601371.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_053610640.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_053610089.1	5	MetaCyc: PWY-7282;KEGG: 00750+2.7.1.35;Reactome: R-HSA-964975;MetaCyc: PWY-7204;Reactome: R-HSA-6798695	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"Neutrophil degranulation"
XP_053603499.1	5	MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7176;Reactome: R-HSA-499943;MetaCyc: PWY-7177	"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation II"
XP_053624491.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053619590.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_053622001.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053617635.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053625001.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_053617555.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_053623039.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053624266.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_053623348.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053623502.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053600355.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_053624554.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053605494.1	32	Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-8851708;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-72203;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Signaling by FGFR2 IIIa TM";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex"
XP_053619033.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_053609531.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053609651.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_053617047.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_053600772.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_053601667.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053599565.1	3	Reactome: R-HSA-5626978;Reactome: R-HSA-193681;Reactome: R-HSA-1660662	"TNFR1-mediated ceramide production";"Ceramide signalling";"Glycosphingolipid metabolism"
XP_053611627.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053621188.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053602067.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_053606309.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_053625225.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053621554.1	8	Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;MetaCyc: PWY-7391;MetaCyc: PWY-7524;Reactome: R-HSA-1989781	"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"PPARA activates gene expression"
XP_053625170.1	5	Reactome: R-HSA-8873719;Reactome: R-HSA-1660499;Reactome: R-HSA-6798695;Reactome: R-HSA-8876198;Reactome: R-HSA-1445148	"RAB geranylgeranylation";"Synthesis of PIPs at the plasma membrane";"Neutrophil degranulation";"RAB GEFs exchange GTP for GDP on RABs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053618294.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053610632.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_053613347.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_053619373.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053609017.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_053624581.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053599541.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_053601004.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053616224.1	6	KEGG: 04070+3.1.3.64+3.1.3.95;MetaCyc: PWY-6580;KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6368;MetaCyc: PWY-6367;Reactome: R-HSA-1660499	"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Synthesis of PIPs at the plasma membrane"
XP_053604667.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053614627.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_053608200.1	16	Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548	"Estrogen-dependent gene expression";"HATs acetylate histones";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks"
XP_053623682.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_053604371.1	7	Reactome: R-HSA-2468052;Reactome: R-HSA-3108214;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-1221632;Reactome: R-HSA-2467813	"Establishment of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Meiotic synapsis";"Separation of Sister Chromatids"
XP_053603803.1	7	Reactome: R-HSA-5658034;Reactome: R-HSA-5358346;Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5362798;Reactome: R-HSA-5632684;Reactome: R-HSA-5632681	"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog ligand biogenesis";"Class B/2 (Secretin family receptors)";"Activation of SMO";"Release of Hh-Np from the secreting cell";"Hedgehog 'on' state";"Ligand-receptor interactions"
XP_053600756.1	3	KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801;Reactome: R-HSA-156590	"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation"
XP_053605158.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053612802.1	5	KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;MetaCyc: PWY-7979	"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)"
XP_053607981.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-73779	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_053612310.1	5	Reactome: R-HSA-9609523;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-5694530	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Cargo concentration in the ER"
XP_053623122.1	3	Reactome: R-HSA-349425;MetaCyc: PWY-7511;Reactome: R-HSA-8951664	"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination";"Neddylation"
XP_053619164.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053615310.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053612771.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_053615985.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053625433.1	20	MetaCyc: PWY-6837;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-735;MetaCyc: PWY-7574;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-7291;Reactome: R-HSA-9033241;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7288;MetaCyc: PWY-5136;MetaCyc: PWY-7858	"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoate metabolism";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"(5Z)-dodecenoate biosynthesis II"
XP_053614282.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053622678.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_053621338.1	5	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-6798695;Reactome: R-HSA-75109	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism";"Acyl chain remodeling of DAG and TAG";"Neutrophil degranulation";"Triglyceride biosynthesis"
XP_053619434.1	56	Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-9010553	"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"UCH proteinases";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs"
XP_053618106.1	2	Reactome: R-HSA-389397;Reactome: R-HSA-416476	"Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events"
XP_053614919.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_053617994.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053611721.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360	"EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_053610203.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate"
XP_053608396.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_053609757.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053604745.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053618015.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053613092.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_053624995.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787	"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Hedgehog 'off' state"
XP_053609468.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053601313.1	3	KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117;MetaCyc: PWY-0	"Arginine and proline metabolism";"Spermine and spermidine degradation I";"Putrescine degradation III"
XP_053611077.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_053624500.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053620937.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_053602530.1	11	KEGG: 04926+2.7.11.1;Reactome: R-HSA-163680;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-380972	"Relaxin signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Human immunodeficiency virus 1 infection";"FOXO-mediated transcription of cell death genes";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_053602650.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs"
XP_053600362.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_053600043.1	7	Reactome: R-HSA-1483148;MetaCyc: PWY-7039;MetaCyc: PWY-3561;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485;KEGG: 00565+3.1.4.4	"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Synthesis of PA";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Ether lipid metabolism"
XP_053605650.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_053605530.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_053610395.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_053608281.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053601346.1	13	Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-5913	"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)"
XP_053599632.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053626029.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_053615454.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053610179.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053606725.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053614077.1	22	Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-2500257	"Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"RAF activation";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"Resolution of Sister Chromatid Cohesion"
XP_053618762.1	13	Reactome: R-HSA-983695;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-139853;Reactome: R-HSA-2871809;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-422356;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-112043	"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"Regulation of insulin secretion";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"PLC beta mediated events"
XP_053612746.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_053624324.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053620699.1	10	MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484	"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)"
XP_053624120.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_053618218.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053606159.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053600880.1	18	MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7176;MetaCyc: PWY-7187;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7221;MetaCyc: PWY-6545;MetaCyc: PWY-7184;Reactome: R-HSA-499943	"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates"
XP_053609642.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053603268.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_053623644.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053604346.1	5	Reactome: R-HSA-389661;Reactome: R-HSA-70895;KEGG: 00640+1.2.4.4;KEGG: 00280+1.2.4.4;MetaCyc: PWY-5046	"Glyoxylate metabolism and glycine degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA"
XP_053622764.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_053601050.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053613201.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053606792.1	3	KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695	"Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation"
XP_053608254.1	9	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway"
XP_053621922.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_053599868.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053626132.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_053608616.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053611337.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053624680.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053623891.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053615361.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053611282.1	4	MetaCyc: PWY-6309;Reactome: R-HSA-71240;KEGG: 00380+3.7.1.3;MetaCyc: PWY-5651	"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde"
XP_053605308.1	6	Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081	"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"MET activates PTK2 signaling"
XP_053599576.1	6	KEGG: 00520+3.5.1.25;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7395;Reactome: R-HSA-446210;MetaCyc: PWY-7077;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetyl-D-galactosamine degradation";"Chitin derivatives degradation"
XP_053607814.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053618526.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_053602542.1	26	Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-69183;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-1362277;Reactome: R-HSA-5655862;Reactome: R-HSA-174417;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-4615885;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5358606;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-8866654;Reactome: R-HSA-6782135;Reactome: R-HSA-69205;Reactome: R-HSA-69091;Reactome: R-HSA-174414;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-6804114;Reactome: R-HSA-174437	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Processive synthesis on the lagging strand";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Transcription of E2F targets under negative control by DREAM complex";"Translesion synthesis by POLK";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"SUMOylation of DNA replication proteins";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"E3 ubiquitin ligases ubiquitinate target proteins";"Dual incision in TC-NER";"G1/S-Specific Transcription";"Polymerase switching";"Processive synthesis on the C-strand of the telomere";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Removal of the Flap Intermediate from the C-strand"
XP_053620284.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_053619259.1	8	KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1	"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_053613543.1	7	KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-5628897	"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes"
XP_053607102.1	9	KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52	"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation"
XP_053617858.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053607365.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_053621078.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053622080.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053599640.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053610938.1	6	MetaCyc: PWY-7391;Reactome: R-HSA-2426168;Reactome: R-HSA-446199;MetaCyc: PWY-922;Reactome: R-HSA-191273;KEGG: 00900+4.1.1.33	"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Synthesis of Dolichyl-phosphate";"Mevalonate pathway I";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis"
XP_053612198.1	14	Reactome: R-HSA-9634638;Reactome: R-HSA-9648025;Reactome: R-HSA-5687128;Reactome: R-HSA-168333;Reactome: R-HSA-3769402;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-450520;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-69273;Reactome: R-HSA-2173788;Reactome: R-HSA-2500257	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"EML4 and NUDC in mitotic spindle formation";"MAPK6/MAPK4 signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Deactivation of the beta-catenin transactivating complex";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HuR (ELAVL1) binds and stabilizes mRNA";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Cyclin A/B1/B2 associated events during G2/M transition";"Downregulation of TGF-beta receptor signaling";"Resolution of Sister Chromatid Cohesion"
XP_053625080.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_053601745.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053623229.1	12	KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7416;MetaCyc: PWY-6803	"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Ether lipid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing"
XP_053614261.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_053604221.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_053625238.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053609192.1	57	Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128	"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling"
XP_053605585.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053607111.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_053606123.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053608193.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_053614917.1	2	Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29	"Threonine catabolism";"Glycine, serine and threonine metabolism"
XP_053609270.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053600461.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053610421.1	5	Reactome: R-HSA-3270619;Reactome: R-HSA-1834941;Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695	"IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"Neutrophil degranulation"
XP_053610408.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053615984.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053609759.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053603701.1	7	KEGG: 00190+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-2151201;Reactome: R-HSA-1268020;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980	"Oxidative phosphorylation";"Cristae formation";"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial protein import";"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"ATP biosynthesis"
XP_053625224.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_053606683.1	6	Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_053622224.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_053612648.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_053625375.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053611079.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_053608847.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-156711	"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events"
XP_053618295.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053616292.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053608262.1	9	Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400	"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_053601143.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053601005.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053607832.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053616225.1	6	MetaCyc: PWY-6368;MetaCyc: PWY-6367;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.64+3.1.3.95;MetaCyc: PWY-6580;KEGG: 00562+3.1.3.64+3.1.3.95	"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism"
XP_053610177.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_053614339.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_053614079.1	22	Reactome: R-HSA-389513;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-6811558;Reactome: R-HSA-5467348;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-2500257;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"CTLA4 inhibitory signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"RAF activation";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Truncations of AMER1 destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"Resolution of Sister Chromatid Cohesion";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_053600354.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_053619931.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
XP_053623573.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_053624555.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053623458.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_053607226.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053620407.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_053599925.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_053606157.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_053618836.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053600150.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053620697.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_053623610.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_053616972.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-72165	"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway"
XP_053599992.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_053610318.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053603463.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_053612679.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_053611339.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053617491.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053615237.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69052	"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state"
XP_053615382.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053611261.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053616028.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053603470.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053617554.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053623560.1	4	KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;MetaCyc: PWY-7437;Reactome: R-HSA-3214847	"Other types of O-glycan biosynthesis";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones"
XP_053617634.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053617188.1	14	Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167238	"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation"
XP_053618098.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053609990.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_053607840.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053608186.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_053617315.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_053616139.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053614483.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053611929.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053609198.1	16	KEGG: 00680+4.2.1.11;MetaCyc: PWY-2221;MetaCyc: PWY-1622;MetaCyc: PWY-5723;MetaCyc: PWY-7218;MetaCyc: PWY-7124;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-6142;KEGG: 00010+4.2.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-7003;Reactome: R-HSA-70263;MetaCyc: PWY-6901;MetaCyc: PWY-5484	"Methane metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Formaldehyde assimilation I (serine pathway)";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)"
XP_053613526.1	3	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10;Reactome: R-HSA-6783984	"One carbon pool by folate";"Glycine, serine and threonine metabolism";"Glycine degradation"
XP_053610625.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053607096.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_053602259.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_053607824.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053601357.1	3	KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117;MetaCyc: PWY-0	"Arginine and proline metabolism";"Spermine and spermidine degradation I";"Putrescine degradation III"
XP_053620970.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053602311.1	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
XP_053610402.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053609361.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053620963.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_053624865.1	11	Reactome: R-HSA-1963642;Reactome: R-HSA-1250196;Reactome: R-HSA-6785631;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-9664565;Reactome: R-HSA-5673001;Reactome: R-HSA-1227986;Reactome: R-HSA-2219530;Reactome: R-HSA-8847993;Reactome: R-HSA-8863795	"PI3K events in ERBB2 signaling";"SHC1 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade";"Signaling by ERBB2";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Activates PTK6 Signaling";"Downregulation of ERBB2 signaling"
XP_053601091.1	15	Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-69017	"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6"
XP_053609239.1	6	MetaCyc: PWY-7290;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433	"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_053611593.1	4	Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
XP_053610185.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053612723.1	4	MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_053609677.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053618666.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053609481.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_053625758.1	3	Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807	"Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_053606406.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_053614363.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_053624314.1	8	Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;KEGG: 00270+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-5481;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;KEGG: 00640+1.1.1.27	"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Cysteine and methionine metabolism";"Superpathway of glucose and xylose degradation";"Pyruvate fermentation to (S)-lactate";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Propanoate metabolism"
XP_053614042.1	6	KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122	"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis"
XP_053603907.1	26	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-389977;Reactome: R-HSA-983189	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"Mitotic Prometaphase";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Post-chaperonin tubulin folding pathway";"Kinesins"
XP_053600958.1	14	MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-7587	"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)"
XP_053600515.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7888	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)"
XP_053606696.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_053603254.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_053599854.1	26	Reactome: R-HSA-8866907;Reactome: R-HSA-918233;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-5617472;Reactome: R-HSA-3899300;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-9617629;Reactome: R-HSA-933541	"Activation of the TFAP2 (AP-2) family of transcription factors";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of transcription cofactors";"RORA activates gene expression";"Estrogen-dependent gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of FOXO transcriptional activity by acetylation";"TRAF6 mediated IRF7 activation"
XP_053618228.1	24	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HCMV Early Events";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors"
XP_053608268.1	6	Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16	"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Triglyceride catabolism";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053624110.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053616949.1	12	KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-7385;KEGG: 00680+4.1.2.13	"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism"
XP_053604091.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053621865.1	6	Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053609454.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_053617695.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053625240.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053600026.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053617716.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_053617405.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053603849.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053619650.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053619418.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_053611363.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_053600894.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_053621314.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053618987.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_053601323.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053603439.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy"
XP_053599736.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_053605401.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053621110.1	4	Reactome: R-HSA-70263;KEGG: 00052+3.1.3.9;KEGG: 00500+3.1.3.9;KEGG: 00010+3.1.3.9	"Gluconeogenesis";"Galactose metabolism";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis"
XP_053603281.1	1	Reactome: R-HSA-419771	"Opsins"
XP_053605691.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-7445	"Betanidin degradation";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation"
XP_053610312.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053602401.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053607479.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053599998.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053611711.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053612757.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_053611483.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053602844.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053601202.1	9	Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-3560783;Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-3656253	"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_053618025.1	10	Reactome: R-HSA-4719377;Reactome: R-HSA-162699;Reactome: R-HSA-4719360;Reactome: R-HSA-913709;MetaCyc: PWY-7921;MetaCyc: PWY-7661;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7979;Reactome: R-HSA-4717374;MetaCyc: PWY-7922	"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"O-linked glycosylation of mucins";"Protein O-mannosylation I (yeast)";"Protein N-glycosylation (Haloferax volcanii)";"N-Glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_053608065.1	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
XP_053615388.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053618092.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053624404.1	13	Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-3928662;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5687128;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Rho GTPase cycle";"EPHB-mediated forward signaling";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"MAPK6/MAPK4 signaling";"Thermogenesis";"Human papillomavirus infection";"G alpha (q) signalling events";"G alpha (12/13) signalling events"
XP_053625672.1	58	MetaCyc: PWY-6945;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7007;Reactome: R-HSA-77346;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17;KEGG: 00903+4.2.1.17;MetaCyc: PWY-5177;Reactome: R-HSA-77350;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6583;MetaCyc: PWY-7654;Reactome: R-HSA-1482798;MetaCyc: PWY-1361;MetaCyc: PWY-5109;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-7779;MetaCyc: PWY-7656;MetaCyc: PWY-5789;Reactome: R-HSA-77288;KEGG: 00930+4.2.1.17;Reactome: R-HSA-77285;KEGG: 00627+4.2.1.17;KEGG: 00280+4.2.1.17;MetaCyc: PWY-7606;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;Reactome: R-HSA-77305;MetaCyc: PWY-6863;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-7094;KEGG: 00623+1.1.1.35;Reactome: R-HSA-77310;KEGG: 00281+4.2.1.17;MetaCyc: PWY-7726;Reactome: R-HSA-77348;KEGG: 00650+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17;KEGG: 00362+4.2.1.17;MetaCyc: PWY-5136;MetaCyc: PWY-6944;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00410+4.2.1.17;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6946;KEGG: 00310+4.2.1.17;MetaCyc: PWY-7216;MetaCyc: PWY-5138;MetaCyc: PWY-7401;MetaCyc: PWY-7778	"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Phenylalanine metabolism";"Methyl ketone biosynthesis (engineered)";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Benzoate degradation";"Carbon fixation pathways in prokaryotes";"Limonene and pinene degradation";"Glutaryl-coa degradation";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Tryptophan metabolism";"Fatty acid elongation";"Propanoate metabolism";"Pyruvate fermentation to butanol I";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Acyl chain remodeling of CL";"Benzoyl-coa degradation I (aerobic)";"Fermentation to 2-methylbutanoate";"Fatty acid degradation";"Methyl tert-butyl ether degradation";"Spodoptera littoralis pheromone biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Caprolactam degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Aminobenzoate degradation";"Valine, leucine and isoleucine degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Carbon fixation pathways in prokaryotes";"Caprolactam degradation";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Pyruvate fermentation to hexanol (engineered)";"Lysine degradation";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid salvage";"Toluene degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Geraniol degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Butanoate metabolism";"Geraniol degradation";"Tryptophan metabolism";"Benzoate degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Androstenedione degradation";"Fatty acid degradation";"Fatty acid elongation";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Lysine degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"2-methylpropene degradation"
XP_053612990.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053611871.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_053610130.1	6	KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;Reactome: R-HSA-189085;MetaCyc: PWY-7900;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Starch biosynthesis";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_053606054.1	27	Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-168271	"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus"
XP_053616137.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053621332.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_053608383.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053615990.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053608470.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins"
XP_053614288.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_053609951.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053599624.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053618674.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053605257.1	11	Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-112382	"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex"
XP_053607501.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_053602257.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053601359.1	3	KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117;MetaCyc: PWY-0	"Arginine and proline metabolism";"Spermine and spermidine degradation I";"Putrescine degradation III"
XP_053600488.1	16	Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-2467813	"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids"
XP_053624934.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_053624072.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_053611702.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053602412.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_053624144.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73779	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_053613836.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053609237.1	6	MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433	"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_053614953.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053610855.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_053610328.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053616493.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053621056.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_053617935.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053619422.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053619605.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_053603574.1	13	Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-216083;Reactome: R-HSA-2022090;Reactome: R-HSA-1474244;Reactome: R-HSA-186797;Reactome: R-HSA-3000157;Reactome: R-HSA-1442490;Reactome: R-HSA-3000178;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-419037;Reactome: R-HSA-2214320	"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Integrin cell surface interactions";"Assembly of collagen fibrils and other multimeric structures";"Extracellular matrix organization";"Signaling by PDGF";"Laminin interactions";"Collagen degradation";"ECM proteoglycans";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"NCAM1 interactions";"Anchoring fibril formation"
XP_053614166.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_053618423.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_053608463.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins"
XP_053621287.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053622389.1	2	Reactome: R-HSA-5601884;Reactome: R-HSA-1221632	"PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis"
XP_053599638.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_053607216.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053599915.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053601506.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_053620010.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053616215.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053611953.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053613295.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_053618768.1	13	Reactome: R-HSA-112043;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-422356;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-2871809;Reactome: R-HSA-139853;Reactome: R-HSA-381676;Reactome: R-HSA-114508;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-983695	"PLC beta mediated events";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"Regulation of insulin secretion";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"FCERI mediated Ca+2 mobilization";"Elevation of cytosolic Ca2+ levels";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Effects of PIP2 hydrolysis";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"
XP_053619246.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_053602223.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_053618989.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_053626138.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_053599862.1	26	Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-933541;Reactome: R-HSA-9617629;Reactome: R-HSA-201722;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-5617472;Reactome: R-HSA-3899300;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-3134973;Reactome: R-HSA-918233;Reactome: R-HSA-8866907;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408	"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF6 mediated IRF7 activation";"Regulation of FOXO transcriptional activity by acetylation";"Formation of the beta-catenin:TCF transactivating complex";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of transcription cofactors";"RORA activates gene expression";"Estrogen-dependent gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"TRAF3-dependent IRF activation pathway";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation"
XP_053611166.1	20	MetaCyc: PWY-7340;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-7007;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-7854;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7606	"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)"
XP_053603437.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"HCMV Early Events";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_053625214.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053604506.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053607477.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053603262.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053613303.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053615270.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053614871.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053609115.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_053616583.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053615125.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053605165.1	8	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_053605548.1	10	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05165+2.7.11.1;Reactome: R-HSA-201722;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3214847	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Ub-specific processing proteases";"Human papillomavirus infection";"Formation of the beta-catenin:TCF transactivating complex";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"HATs acetylate histones"
XP_053623805.1	3	Reactome: R-HSA-1660661;Reactome: R-HSA-6798695;Reactome: R-HSA-9609523	"Sphingolipid de novo biosynthesis";"Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053612192.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053604359.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_053614702.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053606113.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053607108.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053603193.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_053613275.1	3	Reactome: R-HSA-418597;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13	"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_053609937.1	4	KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;Reactome: R-HSA-964975;MetaCyc: PWY-7204	"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_053604440.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_053617235.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053616862.1	6	MetaCyc: PWY-7391;MetaCyc: PWY-6174;Reactome: R-HSA-2426168;KEGG: 00900+2.7.1.36;MetaCyc: PWY-922;Reactome: R-HSA-191273	"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Cholesterol biosynthesis"
XP_053612044.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053606822.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053607943.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053608358.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053624228.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_053625800.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_053610240.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053626045.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053602231.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_053599809.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-2022854;Reactome: R-HSA-5083627	"O-linked glycosylation";"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_053618314.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_053600453.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053604830.1	3	Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2	"Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism"
XP_053621987.1	17	MetaCyc: PWY-4381;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;Reactome: R-HSA-163765;MetaCyc: PWY-6679;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2	"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"Aflatoxin biosynthesis";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"ChREBP activates metabolic gene expression";"Jadomycin biosynthesis";"Fatty acid biosynthesis";"Pyruvate metabolism";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes"
XP_053602369.1	6	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-416993;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network"
XP_053617378.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_053624543.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053609319.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053614988.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053620550.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_053601911.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053605204.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053610094.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053603484.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_053612172.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053605957.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_053624234.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053624516.1	26	Reactome: R-HSA-983189;Reactome: R-HSA-389977;Reactome: R-HSA-8955332;Reactome: R-HSA-389960;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-380320	"Kinesins";"Post-chaperonin tubulin folding pathway";"Carboxyterminal post-translational modifications of tubulin";"Formation of tubulin folding intermediates by CCT/TriC";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes"
XP_053621092.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053608490.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053615970.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053625402.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_053609284.1	9	MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-7112;Reactome: R-HSA-156590;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18;KEGG: 00983+2.5.1.18	"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Drug metabolism - other enzymes"
XP_053604267.1	3	KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_053614227.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053611988.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053616624.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053617117.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053618404.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053618694.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_053601155.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_053625625.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_053606420.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_053607587.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_053599947.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_053609409.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053616184.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_053615156.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053611253.1	5	Reactome: R-HSA-450604;Reactome: R-HSA-430039;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_053606749.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_053619946.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053617024.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053615963.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053625914.1	10	Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-163680;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-200425;Reactome: R-HSA-1445148;Reactome: R-HSA-380972	"Activation of AMPK downstream of NMDARs";"Lipophagy";"AMPK inhibits chREBP transcriptional activation activity";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Carnitine metabolism";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_053619475.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_053602923.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163615	"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation"
XP_053599603.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_053621228.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_053625185.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053600171.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053624987.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_053620642.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_053618431.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_053610536.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_053618340.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing"
XP_053613555.1	4	KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00270+4.2.1.22	"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism"
XP_053604071.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053620263.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_053614610.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_053618144.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053617675.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_053623586.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_053621989.1	17	MetaCyc: PWY-5789;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Jadomycin biosynthesis";"Glyoxylate assimilation";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"Aflatoxin biosynthesis";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism"
XP_053609020.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_053599807.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)"
XP_053625142.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053602671.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053607609.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_053601331.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053625932.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
YP_009166942.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053625074.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_053622074.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053622932.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-5469	"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Sesamin biosynthesis"
XP_053612327.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_053606009.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_053620192.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053611194.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_053618934.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053619784.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053602959.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation"
XP_053604520.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_053625783.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_053624674.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053601100.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_053620125.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053604269.1	3	KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_053616335.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053607076.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_053614194.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053611560.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053602790.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination"
XP_053625130.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053611767.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053623606.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_053622334.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_053604100.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053607589.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053601885.1	8	MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-5743	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"3-hydroxypropanoate cycle"
XP_053615886.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053601071.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_053611573.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_053609407.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053599949.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_053624768.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_053625940.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_053600740.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_053625301.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_053626082.1	4	Reactome: R-HSA-6782315;MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285	"tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis"
XP_053604753.1	5	Reactome: R-HSA-9648895;Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012;Reactome: R-HSA-380994	"Response of EIF2AK1 (HRI) to heme deficiency";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_053621423.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_053624989.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_053623048.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053607735.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_053610764.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053614099.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053616564.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_053602475.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_053616992.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_053620677.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053618995.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_053613431.1	33	Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-3371453	"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HCMV Early Events";"Mitotic Prometaphase";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response"
XP_053615699.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-383280	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway"
XP_053613289.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_053612409.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_053610649.1	4	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_053619599.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-381038	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes"
XP_053625796.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_053606410.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_053611945.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053625938.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
YP_009166948.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053600738.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_053611476.1	5	Reactome: R-HSA-5205685;Reactome: R-HSA-205043;Reactome: R-HSA-209560;Reactome: R-HSA-9020702;Reactome: R-HSA-209543	"Pink/Parkin Mediated Mitophagy";"NRIF signals cell death from the nucleus";"NF-kB is activated and signals survival";"Interleukin-1 signaling";"p75NTR recruits signalling complexes"
XP_053608451.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_053613694.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053601544.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_053616256.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053616614.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_053623030.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053620591.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053612147.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_053618338.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-73856	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination"
XP_053623370.1	52	Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-5601884;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-73980;Reactome: R-HSA-6807505;Reactome: R-HSA-5617472;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-203927;Reactome: R-HSA-167200;Reactome: R-HSA-5578749;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-76061;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-168325;Reactome: R-HSA-427413;Reactome: R-HSA-6782210;Reactome: R-HSA-167242;Reactome: R-HSA-167162;Reactome: R-HSA-5250924;Reactome: R-HSA-167290;Reactome: R-HSA-749476;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-73780;Reactome: R-HSA-6781823;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-76071;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-73863;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-6781827;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-76066;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-1834949	"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Transcription Termination";"RNA polymerase II transcribes snRNA genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"MicroRNA (miRNA) biogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"FGFR2 alternative splicing";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Viral Messenger RNA Synthesis";"NoRC negatively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II HIV Promoter Escape";"B-WICH complex positively regulates rRNA expression";"Pausing and recovery of HIV elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Chain Elongation";"Formation of TC-NER Pre-Incision Complex";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"mRNA Capping";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Termination";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Cytosolic sensors of pathogen-associated DNA"
XP_053618049.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_053601908.1	7	Reactome: R-HSA-445095;Reactome: R-HSA-264870;Reactome: R-HSA-6807878;Reactome: R-HSA-373753;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6798695	"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins";"COPI-mediated anterograde transport";"Nephrin family interactions";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Neutrophil degranulation"
XP_053604719.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_053601921.1	3	KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757	"Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines"
XP_053611961.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053624526.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053600276.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_053609172.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053623174.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_053615251.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053610433.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_053612319.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053614476.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition"
XP_053609329.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_053619369.1	11	Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-3560783;Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-202733;Reactome: R-HSA-3000170;Reactome: R-HSA-3656253	"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"Cell surface interactions at the vascular wall";"Syndecan interactions";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_053613865.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053608364.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-432720;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053624762.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_053603580.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053623363.1	7	KEGG: 00190+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-2151201;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;MetaCyc: PWY-7980	"Oxidative phosphorylation";"Cristae formation";"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial protein import";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"ATP biosynthesis"
XP_053616394.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053615937.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_053625541.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053608209.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053621975.1	11	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"Thermogenesis";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"p38MAPK events";"Human immunodeficiency virus 1 infection";"activated TAK1 mediates p38 MAPK activation";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_053608352.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053620462.1	10	Reactome: R-HSA-3000171;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7394;Reactome: R-HSA-6798695;Reactome: R-HSA-2453902;Reactome: R-HSA-2453864;Reactome: R-HSA-975634;Reactome: R-HSA-977225;MetaCyc: PWY-5691;MetaCyc: PWY-7849	"Non-integrin membrane-ECM interactions";"Purine metabolism";"Urate conversion to allantoin II";"Neutrophil degranulation";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid cycle disease events";"Retinoid metabolism and transport";"Amyloid fiber formation";"Urate conversion to allantoin I";"Urate conversion to allantoin III"
XP_053621836.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053622318.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053623085.1	7	Reactome: R-HSA-4641258;Reactome: R-HSA-201688;Reactome: R-HSA-4641262;Reactome: R-HSA-4086400;Reactome: R-HSA-5663220;Reactome: R-HSA-5368598;Reactome: R-HSA-201681	"Degradation of DVL";"WNT mediated activation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PCP/CE pathway";"RHO GTPases Activate Formins";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"TCF dependent signaling in response to WNT"
XP_053613287.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_053611620.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_053606772.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053612407.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_053620951.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_053600419.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053619597.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-381038	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes"
XP_053614219.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053611180.1	20	MetaCyc: PWY-7288;MetaCyc: PWY-5136;MetaCyc: PWY-7858;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7007;MetaCyc: PWY-6920;MetaCyc: PWY-7854;MetaCyc: PWY-7726;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-7340;MetaCyc: PWY-6837;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6	"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"(5Z)-dodecenoate biosynthesis II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoate metabolism";"Fatty acid degradation"
XP_053609704.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-8001;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-5826	"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis"
XP_053612178.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_053614733.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053615149.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_053604717.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_053625421.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053602784.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053600556.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_053611351.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053614180.1	7	Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"Non-integrin membrane-ECM interactions"
XP_053615317.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_053620006.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053619367.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_053611733.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_053602060.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_053613144.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_053621295.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_053611097.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_053605060.1	8	KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1	"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Glycolysis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis"
XP_053603789.1	2	KEGG: 00230+3.5.3.4;MetaCyc: PWY-5697	"Purine metabolism";"Allantoin degradation to ureidoglycolate I (urea producing)"
XP_053619487.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053610224.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_053599741.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_053600264.1	6	MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761;Reactome: R-HSA-196807;MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1	"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_053610375.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_053621222.1	5	Reactome: R-HSA-196757;KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3;MetaCyc: PWY-6614;MetaCyc: PWY-3841	"Metabolism of folate and pterines";"One carbon pool by folate";"Folate biosynthesis";"Tetrahydrofolate biosynthesis";"Folate transformations II (plants)"
XP_053615939.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_053613864.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053624507.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053606105.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_053622190.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053602657.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053601611.1	3	MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51	"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Other glycan degradation"
XP_053608102.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053612088.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_053613315.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174	"Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_053616395.1	3	Reactome: R-HSA-499943;KEGG: 00240+3.5.4.12;MetaCyc: PWY-7210	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_053609103.1	3	KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664;MetaCyc: PWY-7999	"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K";"Vitamin K-epoxide cycle"
XP_053623846.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053606016.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053622272.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_053612869.1	6	MetaCyc: PWY-7442;Reactome: R-HSA-1474151;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664;MetaCyc: PWY-5663;MetaCyc: PWY-6983	"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis"
XP_053614944.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053603838.1	15	MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-2221;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-8004	"Rubisco shunt";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I"
XP_053624153.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_053603448.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-141444	"Mitotic Prometaphase";"HCMV Early Events";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053612791.1	13	MetaCyc: PWY-7227;MetaCyc: PWY-7198;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7222;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-6545;Reactome: R-HSA-499943	"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates"
XP_053611342.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053621014.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_053611063.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053617218.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053607722.1	5	MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6	"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_053610012.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053614101.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053609557.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053609248.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053619613.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_053605742.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_053615663.1	12	KEGG: 00010+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-6672;MetaCyc: PWY-5132;KEGG: 00620+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5108;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00640+6.2.1.1	"Glycolysis / Gluconeogenesis";"Colupulone and cohumulone biosynthesis";"Cis-genanyl-coa degradation";"Lupulone and humulone biosynthesis";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Adlupulone and adhumulone biosynthesis";"L-isoleucine biosynthesis V";"Methane metabolism";"Chitin degradation to ethanol";"Propanoate metabolism"
XP_053599903.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053613743.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_053623569.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_053614063.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053614342.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_053613716.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053599647.1	11	MetaCyc: PWY-5381;MetaCyc: PWY-6606;MetaCyc: PWY-6608;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6607;MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-7821;KEGG: 00230+3.1.3.5;KEGG: 00240+3.1.3.5;MetaCyc: PWY-7185	"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Tunicamycin biosynthesis";"Purine metabolism";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I"
XP_053621966.1	3	KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_053622087.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053613695.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053616615.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_053610596.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_053607849.1	5	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-6798695;Reactome: R-HSA-1679131;Reactome: R-HSA-2132295	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation";"Trafficking and processing of endosomal TLR";"MHC class II antigen presentation"
XP_053609999.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053616796.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053621507.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053616565.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_053610765.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053618994.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_053604611.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_053611688.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053603512.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Fanconi Anemia Pathway"
XP_053615670.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053622992.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_053619021.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_053609523.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053608595.1	1	Reactome: R-HSA-156581	"Methylation"
XP_053620132.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053611330.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053612670.1	14	Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_053624509.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053621755.1	57	Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-9010553;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-180585	"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Regulation of expression of SLITs and ROBOs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Degradation of DVL";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"UCH proteinases";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G"
XP_053618188.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_053618634.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053602659.1	14	MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6598	"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis"
XP_053610225.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_053600265.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_053604602.1	3	MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_053611786.1	2	Reactome: R-HSA-442982;Reactome: R-HSA-5673001	"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade"
XP_053604059.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053610170.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_053608430.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_053599678.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053599816.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-2022854;Reactome: R-HSA-5083627	"O-linked glycosylation";"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_053618628.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053605827.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_053600123.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053624356.1	8	MetaCyc: PWY-6133;MetaCyc: PWY-5049;MetaCyc: PWY-5394;KEGG: 00950+1.14.16.2;KEGG: 00350+1.14.16.2;Reactome: R-HSA-209905;KEGG: 00790+1.14.16.2;MetaCyc: PWY-3581	"(S)-reticuline biosynthesis II";"Rosmarinic acid biosynthesis II";"Betalamic acid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Catecholamine biosynthesis";"Folate biosynthesis";"(S)-reticuline biosynthesis I"
XP_053603654.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation"
XP_053599843.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits"
XP_053608226.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_053609639.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053603243.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_053616698.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-380972	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_053606461.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053617413.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_053613450.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_053613935.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053605291.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053607437.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_053602291.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_053624689.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053600503.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_053603477.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053609443.1	10	MetaCyc: PWY-6361;MetaCyc: PWY-6362;Reactome: R-HSA-1855167;Reactome: R-HSA-1855191;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6372;MetaCyc: PWY-6369;MetaCyc: PWY-4661;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.158	"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of pyrophosphates in the cytosol";"Synthesis of IPs in the nucleus";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system"
XP_053606976.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_053625576.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-1912420	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi"
XP_053619250.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_053607262.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin"
XP_053609833.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_053614804.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_053623567.1	4	KEGG: 00790+1.14.16.4;Reactome: R-HSA-209931;MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4	"Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism"
XP_053607847.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_053622089.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053608083.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_053621974.1	11	Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-2559580	"p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"Oxidative Stress Induced Senescence"
XP_053600889.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-3232118;Reactome: R-HSA-5693565	"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of transcription factors";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053613852.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_053613161.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053611465.1	5	Reactome: R-HSA-209560;Reactome: R-HSA-9020702;Reactome: R-HSA-205043;Reactome: R-HSA-5205685;Reactome: R-HSA-209543	"NF-kB is activated and signals survival";"Interleukin-1 signaling";"NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy";"p75NTR recruits signalling complexes"
XP_053603121.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_053620690.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_053623906.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_053600157.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053617303.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_053613398.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053601602.1	3	Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807	"Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_053602563.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_053613994.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-68962	"Polymerase switching";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex"
XP_053611793.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053615523.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053605021.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_053616914.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053615061.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_053614206.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053617459.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053603522.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68949	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin"
XP_053609513.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053625915.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053603900.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053619474.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_053617025.1	9	Reactome: R-HSA-9657050;Reactome: R-HSA-110331;Reactome: R-HSA-9656255;Reactome: R-HSA-5649702;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-9656256;Reactome: R-HSA-110329	"Defective OGG1 Localization";"Cleavage of the damaged purine";"Defective OGG1 Substrate Binding";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Processing";"Cleavage of the damaged pyrimidine"
XP_053625638.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-392154;KEGG: 00330+1.14.13.39;MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39	"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Arginine and proline metabolism";"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis"
XP_053625184.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053611645.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053622915.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_053604498.1	8	Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-8953750;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"Transcriptional Regulation by E2F6";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation"
XP_053609546.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_053624117.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_053622473.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053623629.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-163680;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-200425;Reactome: R-HSA-1445148	"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"Activation of AMPK downstream of NMDARs";"AMPK inhibits chREBP transcriptional activation activity";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Carnitine metabolism";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053609285.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053605646.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_053603766.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053608662.1	2	Reactome: R-HSA-9627069;Reactome: R-HSA-111458	"Regulation of the apoptosome activity";"Formation of apoptosome"
XP_053622460.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_053613726.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053599672.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053605777.1	2	Reactome: R-HSA-190373;Reactome: R-HSA-5654726	"FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling"
XP_053601350.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053602570.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_053609663.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_053618695.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_053611037.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053602613.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053619742.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_053615248.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053624896.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_053601154.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_053621235.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053625624.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_053612750.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958	"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_053615279.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053606641.1	2	KEGG: 00513+2.4.1.142;KEGG: 00510+2.4.1.142	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_053612279.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053611511.1	8	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226	"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053602819.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)"
XP_053605205.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053601046.1	1	Reactome: R-HSA-419771	"Opsins"
XP_053603485.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_053604350.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053617666.1	3	KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693	"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism"
XP_053607626.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_053610095.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053600316.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_053624235.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_053603102.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053613274.1	3	Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events"
XP_053613858.1	3	MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_053610978.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053617234.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053615103.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053615045.1	17	Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167238;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167152;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Th1 and Th2 cell differentiation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053621349.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053612103.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_053617516.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053602393.1	40	MetaCyc: PWY-6944;MetaCyc: PWY-5136;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-6583;MetaCyc: PWY-1361;MetaCyc: PWY-7654;MetaCyc: PWY-7401;MetaCyc: PWY-7778;MetaCyc: PWY-7216;MetaCyc: PWY-7656;MetaCyc: PWY-5138;MetaCyc: PWY-5789;MetaCyc: PWY-6946;MetaCyc: PWY-7779;KEGG: 00410+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00903+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-7007;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6945;KEGG: 00360+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7094;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-6863;MetaCyc: PWY-5177;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35	"Androstenedione degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Geraniol degradation";"Fermentation to 2-methylbutanoate";"Pyruvate fermentation to butanol I";"Benzoyl-coa degradation I (aerobic)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"2-methylpropene degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid beta-oxidation IV (unsaturated, even number)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Methyl tert-butyl ether degradation";"beta-Alanine metabolism";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"4-hydroxybenzoate biosynthesis III (plants)";"Limonene and pinene degradation";"Benzoate degradation";"Valine, leucine and isoleucine degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Aminobenzoate degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Phenylalanine metabolism";"Tryptophan metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid elongation";"Propanoate metabolism";"Fatty acid salvage";"Toluene degradation";"Pyruvate fermentation to butanol II (engineered)";"Pyruvate fermentation to hexanol (engineered)";"Glutaryl-coa degradation";"Caprolactam degradation";"Lysine degradation"
XP_053608096.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_053623823.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_053618980.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053624378.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_053622151.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053617543.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_053626044.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053601608.1	3	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation"
XP_053613392.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21	"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism"
XP_053601621.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053599536.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053606368.1	8	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053609230.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053618161.1	10	MetaCyc: PWY-6397;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6317;MetaCyc: PWY-7344;MetaCyc: PWY-7328;Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2	"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism"
XP_053624347.1	7	KEGG: 00360+1.14.16.1;Reactome: R-HSA-2160456;MetaCyc: PWY-6134;MetaCyc: PWY-7158;KEGG: 00790+1.14.16.1;Reactome: R-HSA-8964208;KEGG: 00400+1.14.16.1	"Phenylalanine metabolism";"Phenylketonuria";"L-tyrosine biosynthesis IV";"L-phenylalanine degradation V";"Folate biosynthesis";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis"
XP_053624119.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053623627.1	10	Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-200425;Reactome: R-HSA-380972	"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carnitine metabolism";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_053619386.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053607734.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053620531.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_053610947.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_053615416.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053612997.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053608477.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_053601960.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053615705.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053614195.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053607872.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053617989.1	9	Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_053605250.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053614122.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_053602779.1	6	Reactome: R-HSA-9022537;Reactome: R-HSA-1989781;Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569	"Loss of MECP2 binding ability to the NCoR/SMRT complex";"PPARA activates gene expression";"HCMV Early Events";"HDACs deacetylate histones";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_053615443.1	12	MetaCyc: PWY-3801;Reactome: R-HSA-3322077;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-7817;MetaCyc: PWY-6527;KEGG: 00500+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00520+2.7.7.9;KEGG: 00561+2.7.7.9;Reactome: R-HSA-173599	"Sucrose degradation II (sucrose synthase)";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Starch and sucrose metabolism";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Glycerolipid metabolism";"Formation of the active cofactor, UDP-glucuronate"
XP_053605779.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053604305.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_053607728.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053602250.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053620979.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_053622335.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_053617212.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053611348.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway"
XP_053601884.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972	"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_053611039.1	7	KEGG: 00620+2.3.1.12;Reactome: R-HSA-389661;KEGG: 00020+2.3.1.12;Reactome: R-HSA-70268;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;KEGG: 00010+2.3.1.12	"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis"
XP_053603442.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"HCMV Early Events";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Aggrephagy"
XP_053625075.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_053612559.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_053612277.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053622075.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053615277.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_053616411.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_053600146.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053620948.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_053617423.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053610583.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053609242.1	6	KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433;MetaCyc: PWY-7290;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122	"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis"
XP_053611195.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_053619785.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053605817.1	5	Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-879415;Reactome: R-HSA-532668	"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_053620320.1	5	MetaCyc: PWY-7822;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_053618450.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053601851.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053618618.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_053604884.1	26	Reactome: R-HSA-983189;Reactome: R-HSA-389977;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"Kinesins";"Post-chaperonin tubulin folding pathway";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_053603226.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_053600113.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053624675.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053623653.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053620124.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053610809.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_053613554.1	4	KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22	"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism"
XP_053603840.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053608501.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053612306.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053618145.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053617674.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_053622736.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828	"TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis"
XP_053600798.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-9609690;Reactome: R-HSA-6804757	"SUMOylation of transcription cofactors";"HCMV Early Events";"Regulation of TP53 Degradation"
XP_053622998.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053625736.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053622881.1	33	Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-3232142;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-4551638	"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of ubiquitinylation proteins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HCMV Early Events";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins"
XP_053625881.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053604706.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_053611682.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053619848.1	6	MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system"
XP_053604367.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7417;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453	"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis"
XP_053599743.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_053624932.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_053624074.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053611704.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053599622.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053609180.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053618672.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_053616675.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053613647.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053612767.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_053620871.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-1632852	"Ub-specific processing proteases";"Macroautophagy"
XP_053615560.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-211981;Reactome: R-HSA-211945;Reactome: R-HSA-8937144;Reactome: R-HSA-1989781	"Endogenous sterols";"Xenobiotics";"Phase I - Functionalization of compounds";"Aryl hydrocarbon receptor signalling";"PPARA activates gene expression"
XP_053599695.1	16	Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-174184	"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_053612560.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_053620927.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_053604959.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_053601790.1	11	Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-380259	"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes"
XP_053621334.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_053603419.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053608055.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_053611886.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_053611353.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_053610287.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053612610.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_053618389.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053608740.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_053614010.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053619424.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053609464.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_053602414.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_053623679.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053624142.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167172	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome"
XP_053623237.1	5	Reactome: R-HSA-5545619;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751	"XAV939 inhibits tankyrase, stabilizing AXIN";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases";"Regulation of PTEN stability and activity"
XP_053604671.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053625423.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053600968.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053625768.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_053603264.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053610901.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053616119.1	13	MetaCyc: PWY-7206;MetaCyc: PWY-7184;MetaCyc: PWY-6545;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00240+3.6.1.9;KEGG: 00230+3.6.1.66;Reactome: R-HSA-74259;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00230+3.6.1.9;KEGG: 00500+3.6.1.9	"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Purine metabolism";"Purine catabolism";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism";"Tunicamycin biosynthesis";"Purine metabolism";"Starch and sucrose metabolism"
XP_053608258.1	9	KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400	"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_053613199.1	3	KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662	"Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_053625212.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053601487.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_053623873.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway"
XP_053611010.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_053603309.1	15	Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-5484;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-8004;MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-2221;KEGG: 00010+2.7.1.40	"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Purine metabolism";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Rubisco shunt";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis / Gluconeogenesis"
XP_053610144.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053601671.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053600789.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_053609097.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053606589.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation"
XP_053622989.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_053616347.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053621074.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053611327.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053615229.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_053605269.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA"
XP_053612194.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053609219.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_053601959.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053604790.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053607818.1	2	Reactome: R-HSA-2393930;MetaCyc: PWY-6502	"Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification I"
XP_053602100.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_053625457.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_053623115.1	42	Reactome: R-HSA-1912408;Reactome: R-HSA-110330;Reactome: R-HSA-5625886;Reactome: R-HSA-606279;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-2559586;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-8939236;Reactome: R-HSA-5578749;Reactome: R-HSA-977225;Reactome: R-HSA-912446;Reactome: R-HSA-3214815;Reactome: R-HSA-9609690;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-427359;Reactome: R-HSA-5693607;Reactome: R-HSA-427389;Reactome: R-HSA-9610379;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-3214841;Reactome: R-HSA-1221632;Reactome: R-HSA-201722;Reactome: R-HSA-3214842;Reactome: R-HSA-5693565;Reactome: R-HSA-4551638;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-73728;Reactome: R-HSA-8936459;Reactome: R-HSA-2299718;Reactome: R-HSA-427413;Reactome: R-HSA-3214847;Reactome: R-HSA-171306;Reactome: R-HSA-2559580;Reactome: R-HSA-3214858	"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA methylation";"PRC2 methylates histones and DNA";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation by small RNAs";"Amyloid fiber formation";"Meiotic recombination";"HDACs deacetylate histones";"HCMV Early Events";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"SIRT1 negatively regulates rRNA expression";"Processing of DNA double-strand break ends";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Late Events";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PKMTs methylate histone lysines";"Meiotic synapsis";"Formation of the beta-catenin:TCF transactivating complex";"HDMs demethylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"SUMOylation of chromatin organization proteins";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"RNA Polymerase I Promoter Opening";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Condensation of Prophase Chromosomes";"NoRC negatively regulates rRNA expression";"HATs acetylate histones";"Packaging Of Telomere Ends";"Oxidative Stress Induced Senescence";"RMTs methylate histone arginines"
XP_053614329.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_053604369.1	10	KEGG: 00332+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00330+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00332+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00330+1.2.1.41;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11	"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis"
XP_053618467.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_053615988.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053622543.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053610404.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053625543.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053618232.1	6	Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10	"Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis III";"Drug metabolism - other enzymes"
XP_053609476.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_053605729.1	11	MetaCyc: PWY-3881;MetaCyc: PWY-5659;MetaCyc: PWY-3861;MetaCyc: PWY-882;KEGG: 00520+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-6992;KEGG: 00051+5.3.1.8;MetaCyc: PWY-7586;MetaCyc: PWY-7456;Reactome: R-HSA-4043916	"Mannitol biosynthesis";"GDP-mannose biosynthesis";"Mannitol degradation II";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"1,5-anhydrofructose degradation";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"Defective MPI causes MPI-CDG (CDG-1b)"
XP_053604204.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901	"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs"
XP_053601599.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-1268020	"Processing of SMDT1";"Mitochondrial protein import"
XP_053600600.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_053605440.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression"
XP_053615253.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_053610431.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_053624312.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053610289.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053603252.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_053618387.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_053601923.1	10	Reactome: R-HSA-2514853;Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-445144;Reactome: R-HSA-6814122;Reactome: R-HSA-8934903;Reactome: R-HSA-1483191	"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Receptor Mediated Mitophagy";"Synthesis of PC"
XP_053613764.1	2	KEGG: 00290+4.3.1.19;KEGG: 00260+4.3.1.19	"Valine, leucine and isoleucine biosynthesis";"Glycine, serine and threonine metabolism"
XP_053625228.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053615644.1	5	MetaCyc: PWY-7822;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_053620593.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053618240.1	18	MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801	"Plasmalogen degradation";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Arachidonic acid metabolism";"Acyl chain remodelling of PS"
XP_053614156.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_053610314.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053608453.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053620363.1	4	Reactome: R-HSA-189483;Reactome: R-HSA-917937;MetaCyc: PWY-5874;KEGG: 00860+1.14.14.18	"Heme degradation";"Iron uptake and transport";"Heme degradation I";"Porphyrin and chlorophyll metabolism"
XP_053617624.1	5	KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317	"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_053613197.1	3	KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662	"Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_053621312.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053600892.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-3232118;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565	"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"SUMOylation of transcription factors";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053600358.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_053600825.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053624914.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_053622987.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_053606780.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053617460.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053609099.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_053601231.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053617638.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053624692.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_053613433.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053611329.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway"
XP_053602267.1	5	Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693571	"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)"
XP_053609217.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053623345.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053616896.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_053618826.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_053607514.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053601957.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053620370.1	2	Reactome: R-HSA-3299685;Reactome: R-HSA-211945	"Detoxification of Reactive Oxygen Species";"Phase I - Functionalization of compounds"
XP_053622459.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_053622092.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053619877.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_053625092.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053619908.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_053625459.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_053618238.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053623270.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053615982.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942	"Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism"
XP_053623759.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_053607355.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits"
XP_053625303.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_053607828.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053621421.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_053621408.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053612805.1	4	KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16	"Cysteine and methionine metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Arginine and proline metabolism"
XP_053623192.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
XP_053608556.1	9	MetaCyc: PWY-8052;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-7039;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476	"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"G alpha (q) signalling events"
XP_053611571.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_053603732.1	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_053616689.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053609229.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053614178.1	7	Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation"
XP_053615733.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053617640.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053603258.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_053612097.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053624318.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053625754.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_053601060.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053616372.1	5	KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22	"Sphingolipid metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_053608264.1	9	Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323	"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol"
XP_053599858.1	26	Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-3899300;Reactome: R-HSA-5617472;Reactome: R-HSA-3134973;Reactome: R-HSA-2894862;Reactome: R-HSA-8866907;Reactome: R-HSA-918233;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-933541;Reactome: R-HSA-9617629;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-9013695;Reactome: R-HSA-3371568	"RORA activates gene expression";"Estrogen-dependent gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"TRAF3-dependent IRF activation pathway";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"TRAF6 mediated IRF7 activation";"Regulation of FOXO transcriptional activity by acetylation";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"NOTCH4 Intracellular Domain Regulates Transcription";"Attenuation phase"
XP_053616294.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053625222.1	20	KEGG: 00410+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-6920	"beta-Alanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)"
XP_053614407.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_053611939.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053600775.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_053604060.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053621318.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053620048.1	2	KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_053625781.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5626467	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs"
XP_053610709.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_053616032.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053602660.1	14	MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725	"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_053611407.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053603547.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_053605660.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_053611697.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053620606.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053599726.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_053602717.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053602438.1	7	Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-5689603;Reactome: R-HSA-171319;Reactome: R-HSA-606279;Reactome: R-HSA-5689880;Reactome: R-HSA-5696394	"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"UCH proteinases";"Telomere Extension By Telomerase";"Deposition of new CENPA-containing nucleosomes at the centromere";"Ub-specific processing proteases";"DNA Damage Recognition in GG-NER"
XP_053618776.1	14	MetaCyc: PWY-8052;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;MetaCyc: PWY-8051;KEGG: 00564+3.1.3.4;KEGG: 00600+3.1.3.4;Reactome: R-HSA-75109;Reactome: R-HSA-1483191;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4	"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Sphingolipid metabolism";"Triglyceride biosynthesis";"Synthesis of PC";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism"
XP_053623505.1	11	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167172	"HATs acetylate histones";"Ub-specific processing proteases";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome"
XP_053601333.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053602673.1	5	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-112409	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation"
XP_053617632.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053619520.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053614317.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_053604073.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053622098.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053616356.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053626063.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_053615961.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053618816.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_053602908.1	11	Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040	"Hedgehog 'off' state";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_053599628.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053622106.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053618433.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_053624938.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_053617992.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053624796.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053611251.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053616687.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053625015.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Formation of a pool of free 40S subunits"
XP_053612217.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053615217.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053610049.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_053603866.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_053615452.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053615099.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-606279	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053612099.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053603578.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_053612452.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053617087.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053621179.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053599634.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053613240.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_053599554.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_053610324.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053624148.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053614409.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_053611937.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053614699.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053600160.1	30	Reactome: R-HSA-983168;Reactome: R-HSA-2894862;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-2644606;Reactome: R-HSA-2565942;Reactome: R-HSA-5610780;Reactome: R-HSA-2644607;Reactome: R-HSA-8939902;Reactome: R-HSA-5684264;Reactome: R-HSA-8854050;Reactome: R-HSA-69231;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-1170546;Reactome: R-HSA-400253;Reactome: R-HSA-2122947;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-917937;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of GLI1 by the proteasome";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Regulation of RUNX2 expression and activity";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cyclin D associated events in G1";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Prolactin receptor signaling";"Circadian Clock";"NOTCH1 Intracellular Domain Regulates Transcription";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Iron uptake and transport";"Neddylation"
XP_053617614.1	4	KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183	"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_053610120.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_053606794.1	3	KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695	"Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation"
XP_053607131.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_053623642.1	4	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"ECM proteoglycans";"Laminin interactions"
XP_053600962.1	14	Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-8053	"Synthesis of PA";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II"
XP_053613758.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_053603549.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_053611699.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053619440.1	9	KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52	"Other glycan degradation";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis"
XP_053618764.1	13	Reactome: R-HSA-112043;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-139853;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-114508;Reactome: R-HSA-983695	"PLC beta mediated events";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Elevation of cytosolic Ca2+ levels";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"Effects of PIP2 hydrolysis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"
XP_053624541.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053602719.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053607300.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053621796.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68616	"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication"
XP_053612945.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053607104.1	9	KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52	"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Other glycan degradation"
XP_053616966.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_053602233.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_053626128.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053609769.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053603427.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053621938.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_053620282.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_053608996.1	3	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions"
XP_053608738.1	57	Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257	"Separation of Sister Chromatids";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Degradation of AXIN"
XP_053614319.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_053615850.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053608417.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053607941.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_053607812.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053614867.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053604827.1	3	KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686;Reactome: R-HSA-500753	"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis"
XP_053623504.1	11	Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;Reactome: R-HSA-76042	"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HATs acetylate histones";"Ub-specific processing proteases";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_053625356.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053612910.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_053621640.1	4	KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20;MetaCyc: PWY-5331;Reactome: R-HSA-1614558	"Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism";"Taurine biosynthesis I";"Degradation of cysteine and homocysteine"
XP_053613137.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_053618028.1	3	Reactome: R-HSA-445989;Reactome: R-HSA-1810476;Reactome: R-HSA-933542	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation"
XP_053621089.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053615385.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053612385.1	18	MetaCyc: PWY-6969;MetaCyc: PWY-8086;MetaCyc: PWY-1622;MetaCyc: PWY-5392;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00270+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5913;Reactome: R-HSA-70263;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-561	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II";"Methane metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_053619415.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_053600774.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_053625509.1	5	MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39;Reactome: R-HSA-1222556;Reactome: R-HSA-392154;KEGG: 00330+1.14.13.39	"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Arginine and proline metabolism"
XP_053599995.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053616446.1	4	KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193;Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131	"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis"
XP_053599922.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_053605059.1	8	KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1	"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_053608157.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053602059.1	5	MetaCyc: PWY-6124;Reactome: R-HSA-73817;KEGG: 00230+6.3.2.6;MetaCyc: PWY-7234;MetaCyc: PWY-6123	"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I"
XP_053616975.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-6804760;Reactome: R-HSA-2299718	"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes"
XP_053605602.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053617408.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053610581.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053613603.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_053617421.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_053624552.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053624632.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053600518.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053615441.1	12	MetaCyc: PWY-7343;Reactome: R-HSA-3322077;MetaCyc: PWY-3801;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7238;Reactome: R-HSA-173599;KEGG: 00561+2.7.7.9;KEGG: 00520+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527	"UDP-alpha-D-glucose biosynthesis I";"Glycogen synthesis";"Sucrose degradation II (sucrose synthase)";"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Formation of the active cofactor, UDP-glucuronate";"Glycerolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Starch and sucrose metabolism";"Stachyose degradation"
XP_053622755.1	8	Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-165054	"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA"
XP_053604386.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053625755.1	3	MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451	"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_053603798.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_053625129.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053601002.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053607835.1	5	Reactome: R-HSA-9630221;Reactome: R-HSA-110329;Reactome: R-HSA-9630222;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Defective NTHL1 substrate processing";"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_053616222.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053618292.1	27	Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690	"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events"
XP_053610634.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition"
XP_053610188.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053620090.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_053613809.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6781827	"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_053624868.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_053621632.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_053608683.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689	"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits"
XP_053625372.1	8	MetaCyc: PWY-4984;MetaCyc: PWY-4983;MetaCyc: PWY-7400;Reactome: R-HSA-70635;MetaCyc: PWY-5;KEGG: 00220+4.3.2.1;KEGG: 00250+4.3.2.1;MetaCyc: PWY-5154	"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis IV (archaebacteria)";"Urea cycle";"Canavanine biosynthesis";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)"
XP_053600840.1	20	Reactome: R-HSA-5696400;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-5656121	"Dual Incision in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Translesion synthesis by POLK";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI"
XP_053618956.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053611867.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_053601827.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_053620533.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053618163.1	10	MetaCyc: PWY-7344;MetaCyc: PWY-7328;Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397;MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6317	"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose detoxification";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)"
XP_053624640.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053612804.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_053600668.1	9	Reactome: R-HSA-5218920;Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-4420097;Reactome: R-HSA-2871796;Reactome: R-HSA-2871809;Reactome: R-HSA-193648;Reactome: R-HSA-2029482;Reactome: R-HSA-114604	"VEGFR2 mediated vascular permeability";"Rho GTPase cycle";"G alpha (12/13) signalling events";"VEGFA-VEGFR2 Pathway";"FCERI mediated MAPK activation";"FCERI mediated Ca+2 mobilization";"NRAGE signals death through JNK";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade"
XP_053610628.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053610601.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053603146.1	4	Reactome: R-HSA-3359462;Reactome: R-HSA-8964011;Reactome: R-HSA-3359463;Reactome: R-HSA-196741	"Defective AMN causes hereditary megaloblastic anemia 1";"HDL clearance";"Defective CUBN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_053623821.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_053620189.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053602391.1	40	MetaCyc: PWY-7007;KEGG: 00627+4.2.1.17;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6945;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00903+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-6883;MetaCyc: PWY-6863;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-6583;MetaCyc: PWY-1361;MetaCyc: PWY-7654;MetaCyc: PWY-6944;MetaCyc: PWY-5136;MetaCyc: PWY-6946;MetaCyc: PWY-7779;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7401;MetaCyc: PWY-7778;MetaCyc: PWY-7656;MetaCyc: PWY-7216;MetaCyc: PWY-5138;MetaCyc: PWY-5789	"Methyl ketone biosynthesis (engineered)";"Aminobenzoate degradation";"Phenylalanine metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Butanoate metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Limonene and pinene degradation";"Carbon fixation pathways in prokaryotes";"Benzoate degradation";"Valine, leucine and isoleucine degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Toluene degradation";"Fatty acid salvage";"Pyruvate fermentation to butanol II (engineered)";"Pyruvate fermentation to hexanol (engineered)";"Caprolactam degradation";"Glutaryl-coa degradation";"Lysine degradation";"Tryptophan metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid elongation";"Propanoate metabolism";"Geraniol degradation";"Fermentation to 2-methylbutanoate";"Pyruvate fermentation to butanol I";"Benzoyl-coa degradation I (aerobic)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Androstenedione degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Methyl tert-butyl ether degradation";"Fatty acid degradation";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"2-methylpropene degradation";"Spodoptera littoralis pheromone biosynthesis";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_053614869.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053607105.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053619350.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053622153.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053613139.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_053605545.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053612101.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053621087.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053622966.1	7	Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-110331;Reactome: R-HSA-171306	"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged purine";"Packaging Of Telomere Ends"
XP_053602168.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053602286.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_053606907.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_053603406.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400	"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER"
XP_053606795.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_053626135.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_053606254.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex"
XP_053603715.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_053621925.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_053604537.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053604657.1	4	Reactome: R-HSA-4755609;Reactome: R-HSA-446199;MetaCyc: PWY-6129;KEGG: 00900+2.5.1.87	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"Terpenoid backbone biosynthesis"
XP_053613949.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1	"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism"
XP_053611513.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_053621564.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053602057.1	7	MetaCyc: PWY-6277;MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6121;MetaCyc: PWY-6122;Reactome: R-HSA-73817	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis"
XP_053615688.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_053611670.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053618765.1	13	Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-139853;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-114508;Reactome: R-HSA-983695	"PLC beta mediated events";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Elevation of cytosolic Ca2+ levels";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"Effects of PIP2 hydrolysis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"
XP_053609661.1	13	MetaCyc: PWY-7220;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7198;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7222;KEGG: 00983+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7226;KEGG: 00230+1.17.4.1	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism"
XP_053600814.1	4	Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I"
XP_053619498.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053612070.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_053599918.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053611088.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662	"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling"
XP_053622127.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053625127.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053621190.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053599555.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_053606281.1	29	Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-5696400;Reactome: R-HSA-167160;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-427413;Reactome: R-HSA-6782210	"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"Dual Incision in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"NoRC negatively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_053601537.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_053610858.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_053610325.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053609206.1	13	Reactome: R-HSA-437239;Reactome: R-HSA-5099900;Reactome: R-HSA-167590;Reactome: R-HSA-416993;Reactome: R-HSA-2132295;Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-177504;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-8856828;Reactome: R-HSA-182218	"Recycling pathway of L1";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"MHC class II antigen presentation";"EPH-ephrin mediated repulsion of cells";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation"
XP_053623019.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053613978.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053624992.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163615	"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"PKA activation"
XP_053617615.1	4	Reactome: R-HSA-1855183;MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1	"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism"
XP_053600485.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_053607525.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_053606396.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053622471.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053619181.1	4	Reactome: R-HSA-6807047;Reactome: R-HSA-6807062;KEGG: 00100+1.3.1.72;MetaCyc: PWY-8026	"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol";"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)"
XP_053624614.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053604623.1	6	KEGG: 00053+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17	"Ascorbate and aldarate metabolism";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Caprolactam degradation"
XP_053625471.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_053615521.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053605023.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053602561.1	5	MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)"
XP_053622014.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176974	"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Unwinding of DNA"
XP_053612342.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-8951664;Reactome: R-HSA-8936459	"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Neddylation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_053602023.1	5	Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;MetaCyc: PWY-6853;Reactome: R-HSA-389661;KEGG: 00250+1.2.1.88	"Proline catabolism";"Arginine and proline metabolism";"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation";"Alanine, aspartate and glutamate metabolism"
XP_053609511.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053603343.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-177929	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Signaling by EGFR"
XP_053603062.1	2	KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_053613022.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053614285.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053607592.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053607368.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_053621075.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053614705.1	34	Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-9639288;Reactome: R-HSA-5578749;Reactome: R-HSA-9648025;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-3232142	"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Amino acids regulate mTORC1";"Transcriptional regulation by small RNAs";"EML4 and NUDC in mitotic spindle formation";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"Mitotic Prometaphase";"SUMOylation of ubiquitinylation proteins"
XP_053615379.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053611559.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_053610935.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_053601748.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053612195.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053610618.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_053613956.1	11	Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163359	"PKA activation";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation"
XP_053614443.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_053605305.1	6	Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_053623310.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_053604779.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_053605851.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053608081.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053613163.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_053603123.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_053609112.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_053623027.1	10	Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-2565942;Reactome: R-HSA-983168	"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053613374.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_053620051.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053613225.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_053609831.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053603265.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053608798.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_053599865.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_053621249.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053608936.1	4	Reactome: R-HSA-5358493;Reactome: R-HSA-8849175;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Threonine catabolism";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_053602293.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_053621736.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053622119.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_053599841.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-6791226	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053599912.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053614306.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053606463.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053603241.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_053619425.1	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
XP_053618493.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_053624998.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163359	"PKA activation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation"
XP_053609465.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_053603157.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053625280.1	17	Reactome: R-HSA-69656;Reactome: R-HSA-9616222;Reactome: R-HSA-2559580;Reactome: R-HSA-6804114;Reactome: R-HSA-113501;Reactome: R-HSA-69205;Reactome: R-HSA-69231;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-8953750;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-2173796;Reactome: R-HSA-139915;Reactome: R-HSA-111448;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408	"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional regulation of granulopoiesis";"Oxidative Stress Induced Senescence";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"G1/S-Specific Transcription";"Cyclin D associated events in G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcriptional Regulation by E2F6";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Activation of PUMA and translocation to mitochondria";"Activation of NOXA and translocation to mitochondria";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation"
XP_053605706.1	5	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA"
XP_053602415.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_053602706.1	14	MetaCyc: PWY-7589;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-5981	"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III"
XP_053600121.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053605415.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053610852.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053614639.1	9	Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68689	"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex"
XP_053602960.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-73779	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_053612920.1	7	Reactome: R-HSA-5632681;Reactome: R-HSA-5362798;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5658034	"Ligand-receptor interactions";"Release of Hh-Np from the secreting cell";"Hedgehog 'on' state";"Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"HHAT G278V abrogates palmitoylation of Hh-Np"
XP_053614277.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing"
XP_053611416.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053611705.1	3	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_053604748.1	3	MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315	"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol"
XP_053599694.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053606470.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053618137.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053608054.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053612502.1	15	Reactome: R-HSA-8853659;Reactome: R-HSA-512988;Reactome: R-HSA-2219530;Reactome: R-HSA-114604;Reactome: R-HSA-416476;Reactome: R-HSA-6811558;Reactome: R-HSA-9009391;Reactome: R-HSA-1257604;Reactome: R-HSA-912631;Reactome: R-HSA-912526;Reactome: R-HSA-1660499;Reactome: R-HSA-388841;Reactome: R-HSA-389357;Reactome: R-HSA-1433557;Reactome: R-HSA-1266695	"RET signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"GPVI-mediated activation cascade";"G alpha (q) signalling events";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Extra-nuclear estrogen signaling";"PIP3 activates AKT signaling";"Regulation of signaling by CBL";"Interleukin receptor SHC signaling";"Synthesis of PIPs at the plasma membrane";"Costimulation by the CD28 family";"CD28 dependent PI3K/Akt signaling";"Signaling by SCF-KIT";"Interleukin-7 signaling"
XP_053621335.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_053611557.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes"
XP_053602013.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_053608316.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_053605013.1	6	Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648;Reactome: R-HSA-5632927	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3"
XP_053615377.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053609508.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053619023.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_053619561.1	6	Reactome: R-HSA-6796648;Reactome: R-HSA-5358565;Reactome: R-HSA-5632987;Reactome: R-HSA-5358606;Reactome: R-HSA-5545483;Reactome: R-HSA-912446	"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MLH1";"Meiotic recombination"
XP_053623344.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053607515.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6804756	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation"
XP_053620220.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053601205.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_053604777.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053618022.1	22	MetaCyc: PWY-8013;KEGG: 00030+5.3.1.9;Reactome: R-HSA-5628897;MetaCyc: PWY-3801;MetaCyc: PWY-5054;MetaCyc: PWY-621;KEGG: 00520+5.3.1.9;Reactome: R-HSA-70171;MetaCyc: PWY-6981;MetaCyc: PWY-7238;MetaCyc: PWY-6992;Reactome: R-HSA-6798695;MetaCyc: PWY-622;MetaCyc: PWY-5384;KEGG: 00010+5.3.1.9;Reactome: R-HSA-70263;MetaCyc: PWY-5659;MetaCyc: PWY-7347;KEGG: 00500+5.3.1.9;MetaCyc: PWY-7385;MetaCyc: PWY-5514;MetaCyc: PWY-6142	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Pentose phosphate pathway";"TP53 Regulates Metabolic Genes";"Sucrose degradation II (sucrose synthase)";"D-sorbitol biosynthesis I";"Sucrose degradation III (sucrose invertase)";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin biosynthesis";"Sucrose biosynthesis II";"1,5-anhydrofructose degradation";"Neutrophil degranulation";"Starch biosynthesis";"Sucrose degradation IV (sucrose phosphorylase)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"GDP-mannose biosynthesis";"Sucrose biosynthesis III";"Starch and sucrose metabolism";"1,3-propanediol biosynthesis (engineered)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_053608343.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053613366.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053604613.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_053625896.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-163680;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-200425;Reactome: R-HSA-1445148	"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"Activation of AMPK downstream of NMDARs";"AMPK inhibits chREBP transcriptional activation activity";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Carnitine metabolism";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053610315.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053613486.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053621247.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_053612206.1	13	KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid metabolism";"CS/DS degradation";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis"
XP_053617692.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_053624558.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053600824.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053624915.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_053613741.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_053605498.1	16	Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-8951664;Reactome: R-HSA-75955;Reactome: R-HSA-180585;Reactome: R-HSA-112382;Reactome: R-HSA-1234176;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-983168;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-9010553;Reactome: R-HSA-674695;Reactome: R-HSA-167287	"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation";"RNA Polymerase II Transcription Elongation";"Vif-mediated degradation of APOBEC3G";"Formation of RNA Pol II elongation complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery"
XP_053622117.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053599928.1	9	Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554	"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_053606268.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_053601563.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_053609688.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-1362277	"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex"
XP_053608406.1	6	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Neutrophil degranulation";"Transferrin endocytosis and recycling"
XP_053616666.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053621638.1	4	MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;KEGG: 00270+1.13.11.20;Reactome: R-HSA-1614558	"Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Cysteine and methionine metabolism";"Degradation of cysteine and homocysteine"
XP_053621184.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053615645.1	5	MetaCyc: PWY-7822;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_053624862.1	24	Reactome: R-HSA-4086398;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-6814122;Reactome: R-HSA-392851;Reactome: R-HSA-400042;Reactome: R-HSA-392170;Reactome: R-HSA-8964616;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-418597;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-392451;Reactome: R-HSA-163359;Reactome: R-HSA-9009391;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-8964315;Reactome: R-HSA-428930	"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"G alpha (i) signalling events";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prostacyclin signalling through prostacyclin receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through CDC42";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (z) signalling events";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"G beta:gamma signalling through PI3Kgamma";"Glucagon signaling in metabolic regulation";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor"
XP_053619286.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_053610182.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053609101.1	3	KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664;MetaCyc: PWY-7999	"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K";"Vitamin K-epoxide cycle"
XP_053609128.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_053614279.1	29	Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-5696400;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-167152;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-73762	"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"Dual Incision in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation"
XP_053614557.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053621460.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_053616516.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053607026.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053602350.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_053600662.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053601570.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053600479.1	16	Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-8853884	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX"
XP_053617312.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053605154.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053618139.1	2	Reactome: R-HSA-5578999;Reactome: R-HSA-174403	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling"
XP_053602449.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053619667.1	29	Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-427413;Reactome: R-HSA-5696395;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-167160;Reactome: R-HSA-5696400;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167158	"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"NoRC negatively regulates rRNA expression";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex"
XP_053614138.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053609627.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053607732.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053615617.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053626085.1	3	MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis"
XP_053611651.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053616287.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053611531.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_053599666.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053603801.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_053625398.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053604373.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_053623230.1	18	KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166	"Linoleic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Synthesis of PA"
XP_053618278.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450513	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_053602839.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053607983.1	6	MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7290	"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_053616056.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_053604360.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_053617656.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_053603444.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_053614320.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_053614124.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053605527.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053615567.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"MHC class II antigen presentation";"Neutrophil degranulation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_053605720.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750	"Regulation of PTEN gene transcription";"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"HCMV Early Events";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6"
XP_053601905.1	7	Reactome: R-HSA-375165;Reactome: R-HSA-6798695;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-373753;Reactome: R-HSA-445095;Reactome: R-HSA-264870	"NCAM signaling for neurite out-growth";"Neutrophil degranulation";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Nephrin family interactions";"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_053607874.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053602527.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053600609.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_053619710.1	52	Reactome: R-HSA-6781823;Reactome: R-HSA-73780;Reactome: R-HSA-6782135;Reactome: R-HSA-749476;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-167162;Reactome: R-HSA-167290;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-76071;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-72203;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-6781827;Reactome: R-HSA-1834949;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-76066;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-73980;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-5601884;Reactome: R-HSA-203927;Reactome: R-HSA-167200;Reactome: R-HSA-5578749;Reactome: R-HSA-76042;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-5617472;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-76061;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-168325	"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Chain Elongation";"Dual incision in TC-NER";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Pausing and recovery of HIV elongation";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Estrogen-dependent gene expression";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cytosolic sensors of pathogen-associated DNA";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Termination";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"Viral Messenger RNA Synthesis"
XP_053603834.1	3	Reactome: R-HSA-4086400;Reactome: R-HSA-4608870;Reactome: R-HSA-373080	"PCP/CE pathway";"Asymmetric localization of PCP proteins";"Class B/2 (Secretin family receptors)"
XP_053614948.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_053611320.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_053615397.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053614979.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_053612397.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053614504.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_053607740.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_053617389.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053611124.1	3	KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684	"Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism"
XP_053607547.1	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_053624137.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_053609244.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053625935.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_053611948.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053625450.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_053620195.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053621583.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053616901.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_053622145.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053625568.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053606968.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_053611684.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053622003.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053619004.1	19	Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8964038;Reactome: R-HSA-432142;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-3000484;Reactome: R-HSA-8963888;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-975634;Reactome: R-HSA-3000480	"LDL remodeling";"Regulation of TLR by endogenous ligand";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL clearance";"Platelet sensitization by LDL";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"Scavenging by Class F Receptors";"Chylomicron assembly";"Cell surface interactions at the vascular wall";"VLDL clearance";"Clathrin-mediated endocytosis";"VLDL assembly";"Chylomicron remodeling";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Scavenging by Class A Receptors"
XP_053600076.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_053610119.1	2	Reactome: R-HSA-977225;Reactome: R-HSA-8854214	"Amyloid fiber formation";"TBC/RABGAPs"
XP_053602633.1	3	KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857	"Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis"
XP_053611017.1	4	KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834	"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Spermidine biosynthesis III"
XP_053612051.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053601480.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_053617672.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_053613632.1	11	Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-6782210	"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_053616431.1	56	Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"UCH proteinases";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Degradation of DVL";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation"
XP_053607000.1	2	KEGG: 00040+5.3.1.5;KEGG: 00051+5.3.1.5	"Pentose and glucuronate interconversions";"Fructose and mannose metabolism"
XP_053619472.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053608236.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_053622182.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053616289.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053625182.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053607866.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_053617094.1	13	Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916	"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation"
XP_053608749.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_053605993.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_053623513.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053602993.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_053603524.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053621298.1	3	Reactome: R-HSA-948021;Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Transport to the Golgi and subsequent modification";"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_053600133.1	6	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_053616841.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053618558.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_053602837.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053623670.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053611977.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053601152.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_053609857.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053613256.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-8876725	"Respiratory electron transport";"Protein methylation"
XP_053600943.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_053625743.1	6	MetaCyc: PWY-7511;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"Protein ubiquitination";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_053609189.1	12	KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5655302;Reactome: R-HSA-1839117;Reactome: R-HSA-193648;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Rho GTPase cycle";"Relaxin signaling pathway";"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway"
XP_053604950.1	33	Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-4551638	"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Transcriptional regulation by small RNAs";"snRNP Assembly";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins"
XP_053612569.1	14	MetaCyc: PWY-7039;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-418217;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;Reactome: R-HSA-4086398;KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;Reactome: R-HSA-399997;KEGG: 00562+3.1.4.11	"Phosphatidate metabolism, as a signaling molecule";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Ca2+ pathway";"Phosphatidylinositol signaling system";"PLC beta mediated events";"Acetylcholine regulates insulin secretion";"Inositol phosphate metabolism"
XP_053599674.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053607578.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_053624022.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053600497.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-174084	"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_053603658.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053619519.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053600607.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_053625695.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends"
XP_053600916.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_053605260.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_053614977.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053607549.1	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_053609210.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins"
XP_053612175.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_053617387.1	6	Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938	"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)"
XP_053624139.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73779	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_053619870.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053626042.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-113501	"DNA replication initiation";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_053622864.1	24	Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257	"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HCMV Early Events";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Kinesins";"Aggrephagy";"Resolution of Sister Chromatid Cohesion"
XP_053606892.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053603941.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-975957	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053620661.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-1362409	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis"
XP_053599768.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053612436.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053608778.1	9	MetaCyc: PWY-6142;MetaCyc: PWY-8086;Reactome: R-HSA-196780;Reactome: R-HSA-70263;Reactome: R-HSA-3371599;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;KEGG: 00720+6.4.1.1	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Carbon fixation pathways in prokaryotes"
XP_053623088.1	6	KEGG: 00040+1.1.1.22;KEGG: 00053+1.1.1.22;MetaCyc: PWY-7346;Reactome: R-HSA-173599;MetaCyc: PWY-7820;KEGG: 00520+1.1.1.22	"Pentose and glucuronate interconversions";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Formation of the active cofactor, UDP-glucuronate";"Teichuronic acid biosynthesis (B. subtilis 168)";"Amino sugar and nucleotide sugar metabolism"
XP_053615846.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053624298.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053616865.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
XP_053617232.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053599989.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053606787.1	11	Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5358606;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554	"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_053622980.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_053617467.1	2	KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053606580.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053600780.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_053617647.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053625188.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-76042	"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_053605986.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053625634.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053612090.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_053611027.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053602986.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053606207.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_053601067.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events"
XP_053613249.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_053620831.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_053604604.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_053623306.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_053607419.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-1679131;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"MHC class II antigen presentation";"Neutrophil degranulation";"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_053626079.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate"
XP_053602004.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-111367	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs"
XP_053618552.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053616635.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053617903.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_053610129.1	6	KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;Reactome: R-HSA-189085;MetaCyc: PWY-7900;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Starch biosynthesis";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_053600169.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053614690.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053623559.1	4	Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;MetaCyc: PWY-7437	"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation"
XP_053613075.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053615244.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_053601584.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053606376.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination"
XP_053603652.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-5676590	"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling"
XP_053608756.1	4	KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism"
XP_053611310.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_053624028.1	6	KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66	"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system"
XP_053605031.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-181429	"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_053609397.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053612653.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_053599526.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053605371.1	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_053602710.1	14	MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725	"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_053609760.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053619527.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053612187.1	12	MetaCyc: PWY-7221;Reactome: R-HSA-399719;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-447038;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-9617324	"Guanosine ribonucleotides de novo biosynthesis";"Trafficking of AMPA receptors";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Synaptic adhesion-like molecules";"NrCAM interactions";"RAF/MAP kinase cascade";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_053618089.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053617375.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053614771.1	4	Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053613335.1	11	Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_053614114.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867	"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex"
XP_053624163.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053618640.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053603818.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_053609084.1	57	Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-6798695;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-69017	"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Neutrophil degranulation";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6"
XP_053604067.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053624225.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_053606898.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_053606981.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053607556.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_053626048.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053601604.1	3	Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807	"Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_053610974.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053609906.1	12	Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-112382	"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex"
XP_053608355.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053620465.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053618868.1	5	Reactome: R-HSA-5221030;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-3108214	"TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins"
XP_053609773.1	10	KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695	"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Sphingolipid metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"HS-GAG degradation";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Neutrophil degranulation"
XP_053603747.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053621972.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_053606352.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053611690.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053601069.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053611029.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053625274.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053618190.1	5	KEGG: 00010+4.1.1.32;KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00620+4.1.1.32	"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism"
XP_053617649.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053607417.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053607738.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_053613247.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_053619273.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829	"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_053607996.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_053621486.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_053623103.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-381038	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"XBP1(S) activates chaperone genes"
XP_053624765.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_053620070.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_053611930.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053613862.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053606160.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053610127.1	6	KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;MetaCyc: PWY-5067;Reactome: R-HSA-189085;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1	"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch biosynthesis";"Starch and sucrose metabolism"
XP_053621741.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053610014.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_053620521.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_053617764.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053604271.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053606484.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053611344.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_053600058.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_053614811.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053609399.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053616338.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053607252.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053619260.1	8	KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1	"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis"
XP_053614140.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_053616078.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_053623999.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_053602519.1	5	Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920	"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability"
XP_053620128.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053625726.1	11	MetaCyc: PWY-6963;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2;KEGG: 00220+6.3.1.2;Reactome: R-HSA-210455;Reactome: R-HSA-8964539;MetaCyc: PWY-5675;MetaCyc: PWY-6549;MetaCyc: PWY-381;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2	"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Arginine biosynthesis";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glutamate and glutamine metabolism";"Nitrate reduction V (assimilatory)";"L-glutamine biosynthesis III";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism"
XP_053620101.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053606451.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_053612189.1	12	Reactome: R-HSA-399719;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001;Reactome: R-HSA-447038	"Trafficking of AMPA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade";"NrCAM interactions"
XP_053611942.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053610153.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053622994.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_053620688.1	10	KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385	"Methane metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)"
XP_053600255.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_053600794.1	6	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-5632684;Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-8866654	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Hedgehog 'on' state";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053604069.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053599975.1	16	Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-8853884	"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX"
XP_053619993.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-73762	"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation"
XP_053616995.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053610507.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_053602472.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_053618992.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053616500.1	2	Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11	"Tryptophan catabolism";"Tryptophan metabolism"
XP_053613915.1	52	Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-68827	"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Hedgehog 'on' state";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex"
XP_053617678.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_053602669.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053613473.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053613380.1	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_053600909.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053609085.1	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_053623886.1	19	Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-8950505;Reactome: R-HSA-5626467;Reactome: R-HSA-5625970;Reactome: R-HSA-418885;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-8964616;Reactome: R-HSA-428543;Reactome: R-HSA-194840;Reactome: R-HSA-3928662;Reactome: R-HSA-182971;Reactome: R-HSA-389359;Reactome: R-HSA-5687128;Reactome: R-HSA-114604;Reactome: R-HSA-5627123;Reactome: R-HSA-4420097;Reactome: R-HSA-5663220	"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate IQGAPs";"RHO GTPases activate KTN1";"DCC mediated attractive signaling";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"G beta:gamma signalling through CDC42";"Inactivation of CDC42 and RAC1";"Rho GTPase cycle";"EPHB-mediated forward signaling";"EGFR downregulation";"CD28 dependent Vav1 pathway";"MAPK6/MAPK4 signaling";"GPVI-mediated activation cascade";"RHO GTPases activate PAKs";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate Formins"
XP_053624224.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_053603191.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-983170	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_053606111.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053601605.1	3	KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
XP_053604246.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053610975.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053613301.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053608354.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053611679.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053616581.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053611237.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_053612339.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_053621903.1	4	Reactome: R-HSA-9613829;Reactome: R-HSA-9646399;Reactome: R-HSA-3899300;Reactome: R-HSA-9615710	"Chaperone Mediated Autophagy";"Aggrephagy";"SUMOylation of transcription cofactors";"Late endosomal microautophagy"
XP_053609702.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_053610098.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053602208.1	3	KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740;MetaCyc: PWY-7999	"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle"
XP_053605208.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053619211.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053619359.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_053624238.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053614006.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053612496.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053611951.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053621647.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053599966.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_053613334.1	11	Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-205043;Reactome: R-HSA-2122948	"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_053614984.1	57	Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-6798695;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346	"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Neutrophil degranulation";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Degradation of GLI1 by the proteasome";"UCH proteinases";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis"
XP_053617170.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053614115.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053602897.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_053618698.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_053618421.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_053608461.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159231	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_053620351.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_053613074.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053611860.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits"
XP_053619686.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_053618408.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3000178	"Protein ubiquitination";"ECM proteoglycans"
XP_053599687.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_053606226.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053624776.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787	"G alpha (z) signalling events";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Hedgehog 'off' state"
XP_053622047.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_053615245.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_053617972.1	24	Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Kinesins";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation"
XP_053602782.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053624647.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_053620982.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_053613411.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053611984.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_053611648.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053606955.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_053625555.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_053607503.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_053606518.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053617028.1	18	KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7783;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166	"Linoleic acid metabolism";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Plasmalogen degradation";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Synthesis of PA"
XP_053610222.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_053600262.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053601739.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053604495.1	4	Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;MetaCyc: PWY-7437	"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation"
XP_053619126.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053605143.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_053626090.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_053616554.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_053605005.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
XP_053614237.1	8	Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-432040	"Hedgehog 'off' state";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_053613142.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_053621752.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053622707.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_053608592.1	10	MetaCyc: PWY-6365;KEGG: 04070+2.7.1.159;Reactome: R-HSA-1855204;KEGG: 00562+2.7.1.134+2.7.1.159;Reactome: R-HSA-983231;MetaCyc: PWY-4661;MetaCyc: PWY-6554;MetaCyc: PWY-6366;Reactome: R-HSA-1855167;MetaCyc: PWY-6362	"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Factors involved in megakaryocyte development and platelet production";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_053603515.1	3	MetaCyc: PWY-7800;MetaCyc: PWY-7799;Reactome: R-HSA-2514859	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_053606900.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_053611746.1	10	Reactome: R-HSA-196757;MetaCyc: PWY-1722;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-6613;MetaCyc: PWY-5030;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909	"Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations I";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)"
XP_053623156.1	7	MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11	"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system"
XP_053617366.1	5	Reactome: R-HSA-6802946;Reactome: R-HSA-5675221;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000	"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation"
XP_053604530.1	19	Reactome: R-HSA-380270;MetaCyc: PWY-7222;Reactome: R-HSA-380320;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7226;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7224;MetaCyc: PWY-7227;MetaCyc: PWY-7197;MetaCyc: PWY-7198	"Recruitment of mitotic centrosome proteins and complexes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of NuMA to mitotic centrosomes";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_053618924.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053604737.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_053599974.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_053610218.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053602050.1	7	KEGG: 00250+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14	"Alanine, aspartate and glutamate metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism"
XP_053611481.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053616994.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053613914.1	52	Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-180585	"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Degradation of DVL";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G"
XP_053622922.1	12	KEGG: 00130+2.5.1.39;MetaCyc: PWY-6978;Reactome: R-HSA-1268020;MetaCyc: PWY-6708;MetaCyc: PWY-5855;MetaCyc: PWY-5871;MetaCyc: PWY-5857;Reactome: R-HSA-2142789;MetaCyc: PWY-5873;MetaCyc: PWY-5872;MetaCyc: PWY-5870;MetaCyc: PWY-5856	"Ubiquinone and other terpenoid-quinone biosynthesis";"Plastoquinol-9 biosynthesis II";"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)"
XP_053618148.1	2	KEGG: 04150+2.7.11.24;Reactome: R-HSA-5687128	"mTOR signaling pathway";"MAPK6/MAPK4 signaling"
XP_053612337.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053611239.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_053600722.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_053606522.1	5	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;MetaCyc: PWY-7511	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Protein ubiquitination"
XP_053616562.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_053613692.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053601542.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_053611361.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_053601321.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053624433.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_053601308.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053602403.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053624678.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053603283.1	3	Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9	"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate"
XP_053605693.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-5469	"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Sesamin biosynthesis"
XP_053621649.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053622078.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053604093.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053625078.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_053617486.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053611198.1	4	Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2	"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053621080.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053606766.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053607725.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053617765.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053607887.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053621816.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_053622049.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_053622338.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_053602761.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053619202.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053624080.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053614198.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053609711.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_053600439.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053606814.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053625275.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053622120.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_053599755.1	8	MetaCyc: PWY-1861;Reactome: R-HSA-5659996;KEGG: 00710+5.3.1.6;MetaCyc: PWY-5723;KEGG: 00030+5.3.1.6;KEGG: 00051+5.3.1.6;Reactome: R-HSA-6791461;Reactome: R-HSA-71336	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"RPIA deficiency: failed conversion of R5P to RU5P";"Carbon fixation in photosynthetic organisms";"Rubisco shunt";"Pentose phosphate pathway";"Fructose and mannose metabolism";"RPIA deficiency: failed conversion of RU5P to R5P";"Pentose phosphate pathway"
XP_053601418.1	24	Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin"
XP_053600281.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_053625120.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_053616392.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053614713.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053624764.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_053620452.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_053618322.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053614481.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_053611454.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053614239.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-983231	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Factors involved in megakaryocyte development and platelet production"
XP_053615953.1	5	KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-7560;MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7	"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism"
XP_053622144.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053604412.1	3	Reactome: R-HSA-9634638;Reactome: R-HSA-525793;Reactome: R-HSA-5663220	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis";"RHO GTPases Activate Formins"
XP_053611685.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053609586.1	14	Reactome: R-HSA-2500257;Reactome: R-HSA-380259;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Resolution of Sister Chromatid Cohesion";"Loss of Nlp from mitotic centrosomes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_053619143.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053625928.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053621656.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053610768.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053625901.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_053616003.1	7	KEGG: 04070+2.7.1.67;MetaCyc: PWY-6352;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;MetaCyc: PWY-6351;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660499	"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane"
XP_053611263.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053601223.1	14	Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801	"Polymerase switching";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair"
XP_053619116.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053614990.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053604086.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053624672.1	16	Reactome: R-HSA-975155;Reactome: R-HSA-975138;Reactome: R-HSA-9020702;Reactome: R-HSA-975871;Reactome: R-HSA-166058;Reactome: R-HSA-6811558;Reactome: R-HSA-5602498;Reactome: R-HSA-1257604;Reactome: R-HSA-5603037;Reactome: R-HSA-1810476;Reactome: R-HSA-5602680;Reactome: R-HSA-3134963;Reactome: R-HSA-5603041;Reactome: R-HSA-209543;Reactome: R-HSA-975110;Reactome: R-HSA-1236974	"MyD88 dependent cascade initiated on endosome";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"Interleukin-1 signaling";"MyD88 cascade initiated on plasma membrane";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88 deficiency (TLR2/4)";"PIP3 activates AKT signaling";"IRAK4 deficiency (TLR5)";"RIP-mediated NFkB activation via ZBP1";"MyD88 deficiency (TLR5)";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"IRAK4 deficiency (TLR2/4)";"p75NTR recruits signalling complexes";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"ER-Phagosome pathway"
XP_053601302.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis"
XP_053616876.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053606243.1	8	Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-442720	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"DARPP-32 events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase"
XP_053613408.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053617493.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_053601548.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_053603461.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_053623571.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_053619933.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053611192.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_053604257.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_053618411.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3000178	"Protein ubiquitination";"ECM proteoglycans"
XP_053609245.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import"
XP_053625934.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
YP_009166944.1	7	KEGG: 00190+7.1.1.2;Reactome: R-HSA-6799198;MetaCyc: PWY-5083;MetaCyc: PWY-6692;Reactome: R-HSA-611105;MetaCyc: PWY-4302;MetaCyc: PWY-3781	"Oxidative phosphorylation";"Complex I biogenesis";"NAD/NADH phosphorylation and dephosphorylation";"Fe(II) oxidation";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration I (cytochrome c)"
XP_053606534.1	8	Reactome: R-HSA-975957;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_053622072.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053620194.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053620560.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053611990.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053603445.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-141444	"HCMV Early Events";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053614759.1	24	Reactome: R-HSA-8964616;Reactome: R-HSA-381676;Reactome: R-HSA-456926;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-392451;Reactome: R-HSA-9009391;Reactome: R-HSA-163359;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-4086398;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-6814122;Reactome: R-HSA-500657;Reactome: R-HSA-392851;Reactome: R-HSA-392170;Reactome: R-HSA-400042	"G beta:gamma signalling through CDC42";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"G beta:gamma signalling through PI3Kgamma";"Extra-nuclear estrogen signaling";"Glucagon signaling in metabolic regulation";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"G alpha (i) signalling events";"G alpha (s) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Presynaptic function of Kainate receptors";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 12";"Adrenaline,noradrenaline inhibits insulin secretion"
XP_053610674.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_053604548.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053621469.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_053601579.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163615	"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Hedgehog 'off' state";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation"
XP_053602359.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_053601257.1	18	MetaCyc: PWY-5913;MetaCyc: PWY-6638;KEGG: 00220+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7117;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-7115;KEGG: 00401+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7383	"Partial TCA cycle (obligate autotrophs)";"Sulfolactate degradation III";"Arginine biosynthesis";"Arginine and proline metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Cysteine and methionine metabolism";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Alanine, aspartate and glutamate metabolism";"(R)-cysteate degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Novobiocin biosynthesis";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_053618334.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695	"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_053607875.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053603703.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_053600470.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_053600383.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053615702.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_053609339.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_053601412.1	24	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors"
XP_053613318.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053626084.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_053610423.1	5	Reactome: R-HSA-3134975;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-3249367	"Regulation of innate immune responses to cytosolic DNA";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"STAT6-mediated induction of chemokines"
XP_053604223.1	6	Reactome: R-HSA-196819;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6898;MetaCyc: PWY-6907;MetaCyc: PWY-6908;MetaCyc: PWY-7356	"Vitamin B1 (thiamin) metabolism";"Thiamine metabolism";"Thiamine salvage III";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage IV (yeast)"
XP_053624536.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053624656.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_053606121.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053623697.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053607113.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_053603150.1	7	MetaCyc: PWY-6737;Reactome: R-HSA-70221;MetaCyc: PWY-5941;MetaCyc: PWY-6724;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;KEGG: 00500+2.4.1.25	"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Starch degradation II";"Sucrose biosynthesis II";"Neutrophil degranulation";"Starch and sucrose metabolism"
XP_053602506.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053612085.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_053618328.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_053613395.1	4	MetaCyc: PWY-7887;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-6823	"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_053616980.1	11	Reactome: R-HSA-174437;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607	"Removal of the Flap Intermediate from the C-strand";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends"
XP_053619346.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053602323.1	7	Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00330+2.5.1.16	"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism"
XP_053606824.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_053615363.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053623893.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053622110.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053603043.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053619313.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053618800.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_053613203.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053624232.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053611550.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_053615370.1	4	KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;Reactome: R-HSA-4549349;KEGG: 00513+2.4.1.257+2.4.1.132	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Various types of N-glycan biosynthesis"
XP_053621094.1	6	KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_053612174.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_053610459.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_053607406.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053620227.1	7	Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.7;MetaCyc: PWY-6610;MetaCyc: PWY-6605;MetaCyc: PWY-7807;MetaCyc: PWY-7805;Reactome: R-HSA-74217	"Neutrophil degranulation";"Purine metabolism";"Adenine salvage";"Adenine and adenosine salvage II";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Purine salvage"
XP_053607715.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_053619899.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_053614757.1	2	MetaCyc: PWY-6938;Reactome: R-HSA-430039	"NADH repair";"mRNA decay by 5' to 3' exoribonuclease"
XP_053617978.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_053621232.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053614550.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053621467.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_053618692.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_053599675.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053601577.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615	"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation"
XP_053601311.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_053618625.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053600186.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_053620988.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_053609282.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053610543.1	8	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway"
XP_053625694.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693607	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends"
XP_053612030.1	22	MetaCyc: PWY-7728;MetaCyc: PWY-7606;MetaCyc: PWY-7049;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7724;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7619;MetaCyc: PWY-7726;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7727;MetaCyc: PWY-7592;MetaCyc: PWY-7053;MetaCyc: PWY-5353;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-6958	"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Juniperonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis I (lower eukaryotes)"
XP_053610201.1	5	MetaCyc: PWY-7822;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_053603964.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_053609337.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_053613924.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053611723.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053620644.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_053600268.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053610228.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-983231	"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Factors involved in megakaryocyte development and platelet production"
XP_053615593.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053607343.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_053600712.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_053622841.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053625912.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053624240.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053611642.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053610666.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053617095.1	5	Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389960	"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_053625431.1	3	Reactome: R-HSA-1369062;Reactome: R-HSA-9029569;Reactome: R-HSA-8964058	"ABC transporters in lipid homeostasis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling"
XP_053623699.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053625289.1	17	Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-69231;Reactome: R-HSA-69656;Reactome: R-HSA-2559580;Reactome: R-HSA-9616222;Reactome: R-HSA-6804114;Reactome: R-HSA-113501;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-1362300;Reactome: R-HSA-8953750;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-2173796;Reactome: R-HSA-139915;Reactome: R-HSA-111448	"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Cyclin D associated events in G1";"Cyclin A:Cdk2-associated events at S phase entry";"Oxidative Stress Induced Senescence";"Transcriptional regulation of granulopoiesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcriptional Regulation by E2F6";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Activation of PUMA and translocation to mitochondria";"Activation of NOXA and translocation to mitochondria"
XP_053613538.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_053610607.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053610497.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053602569.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_053620588.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053603614.1	4	Reactome: R-HSA-198693;Reactome: R-HSA-5674400;Reactome: R-HSA-9615017;Reactome: R-HSA-9614399	"AKT phosphorylates targets in the nucleus";"Constitutive Signaling by AKT1 E17K in Cancer";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of localization of FOXO transcription factors"
XP_053624316.1	8	KEGG: 00640+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-5481;KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27;Reactome: R-HSA-70268	"Propanoate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Pyruvate fermentation to (S)-lactate";"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism"
XP_053603256.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_053619857.1	6	Reactome: R-HSA-427359;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772	"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_053599856.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_053611861.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053618420.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_053606912.1	17	MetaCyc: PWY-6611;MetaCyc: PWY-7179-1;MetaCyc: PWY-5532;MetaCyc: PWY-4202;MetaCyc: PWY-5695;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-6620;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6609;Reactome: R-HSA-74217;MetaCyc: PWY-6627;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6644	"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II";"Nucleoside and nucleotide degradation (archaea)";"Arsenate detoxification I (mammalian)";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Purine catabolism";"Guanine and guanosine salvage";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage III";"Purine salvage";"Salinosporamide A biosynthesis";"Purine metabolism";"Fluoroacetate and fluorothreonine biosynthesis"
XP_053608558.1	9	Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-8052	"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis"
XP_053615837.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_053610133.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053623011.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053615993.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_053604019.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_053614176.1	7	Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"Non-integrin membrane-ECM interactions"
XP_053626091.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_053607094.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053607826.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053605619.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053618236.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053623474.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
XP_053609472.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_053621406.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053623183.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_053619629.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053600349.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_053610780.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_053616580.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_053622096.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053613104.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053602846.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-6598	"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis"
XP_053618822.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_053608151.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"G alpha (i) signalling events";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_053616358.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053615273.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_053613812.1	13	MetaCyc: PWY-5497;MetaCyc: PWY-5030;KEGG: 00670+6.3.4.3;MetaCyc: PWY-3841;MetaCyc: PWY-2201;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2161;MetaCyc: PWY-6613;MetaCyc: PWY-7909;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9	"Purine nucleobases degradation II (anaerobic)";"L-histidine degradation III";"One carbon pool by folate";"Folate transformations II (plants)";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Folate polyglutamylation";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"One carbon pool by folate"
XP_053606110.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053620498.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_053620621.1	40	Reactome: R-HSA-9018519;Reactome: R-HSA-8851708;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-5617472;Reactome: R-HSA-72163;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-203927;Reactome: R-HSA-75955;Reactome: R-HSA-5578749;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-6782135;Reactome: R-HSA-5601884;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-6803529	"Estrogen-dependent gene expression";"Signaling by FGFR2 IIIa TM";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Elongation";"Transcriptional regulation by small RNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"FGFR2 alternative splicing"
XP_053603190.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport"
XP_053600117.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053605813.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-9018519;Reactome: R-HSA-8939211;Reactome: R-HSA-3371568	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Estrogen-dependent gene expression";"ESR-mediated signaling";"Attenuation phase"
XP_053603394.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_053624406.1	13	KEGG: 04926+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-5687128;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-193648	"Relaxin signaling pathway";"EPHB-mediated forward signaling";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"Thermogenesis";"G alpha (12/13) signalling events";"Human papillomavirus infection";"G alpha (q) signalling events";"MAPK6/MAPK4 signaling";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"NRAGE signals death through JNK"
XP_053617171.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053609456.1	12	KEGG: 00670+2.1.2.2;MetaCyc: PWY-6122;Reactome: R-HSA-196780;KEGG: 00230+6.3.4.13;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6121;MetaCyc: PWY-6613;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.9;KEGG: 00230+6.3.3.1;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6277	"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis II";"Biotin transport and metabolism";"Purine metabolism";"Aminoacyl-tRNA biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Purine metabolism";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_053615109.1	4	KEGG: 00970+6.1.1.11;Reactome: R-HSA-2408557;Reactome: R-HSA-379716;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"Cytosolic tRNA aminoacylation";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_053611950.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053625448.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_053611435.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_053600024.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053617714.1	5	Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665	"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells"
XP_053621316.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053619210.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053622838.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053599734.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_053604808.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053607758.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_053605399.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053602399.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053610052.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053609710.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053609517.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_053624081.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053602567.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_053611905.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053611797.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053621054.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_053606332.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_053623466.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_053602760.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053615527.1	15	Reactome: R-HSA-9665249;Reactome: R-HSA-9665245;Reactome: R-HSA-9665246;Reactome: R-HSA-5637810;Reactome: R-HSA-1236382;Reactome: R-HSA-1227986;Reactome: R-HSA-9665247;Reactome: R-HSA-9665244;Reactome: R-HSA-9664565;Reactome: R-HSA-9665233;Reactome: R-HSA-9634285;Reactome: R-HSA-9665250;Reactome: R-HSA-8863795;Reactome: R-HSA-9652282;Reactome: R-HSA-9665251	"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to neratinib";"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to sapitinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to trastuzumab";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to AEE788";"Downregulation of ERBB2 signaling";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to lapatinib"
XP_053603576.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_053614164.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_053619187.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_053611882.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053622681.1	6	KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920;MetaCyc: PWY-7426	"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_053601504.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_053615839.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053617983.1	5	KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403	"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_053604017.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_053613828.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053622108.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053601531.1	4	MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation"
XP_053599626.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053618818.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_053625121.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-937072	"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_053620706.1	10	KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11	"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis"
XP_053622121.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_053605906.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_053615449.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_053624875.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_053609667.1	56	Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-174178;Reactome: R-HSA-5678895	"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"UCH proteinases";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis"
XP_053612449.1	31	MetaCyc: PWY-7664;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;MetaCyc: PWY-6519;MetaCyc: PWY-7723;MetaCyc: PWY-8049;MetaCyc: PWY-5142;MetaCyc: PWY-7388;MetaCyc: PWY-5367;MetaCyc: PWY-8012;MetaCyc: PWY-7858;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-5971;Reactome: R-HSA-2426168;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-8047;MetaCyc: PWY-5366;MetaCyc: PWYG-321;Reactome: R-HSA-163765;MetaCyc: PWY-5994;MetaCyc: PWY-7746;MetaCyc: PWY-4381;MetaCyc: PWY-7663;MetaCyc: PWY-6799;Reactome: R-HSA-199220;MetaCyc: PWY-5989;MetaCyc: PWY-5966-1;Reactome: R-HSA-75105;MetaCyc: PWY-5973	"Oleate biosynthesis IV (anaerobic)";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Bacterial bioluminescence";"Pederin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Petroselinate biosynthesis";"Mupirocin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Bryostatin biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Vitamin B5 (pantothenate) metabolism";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"Cis-vaccenate biosynthesis"
XP_053603632.1	3	MetaCyc: PWY-5963;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9	"Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_053607469.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_053617429.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_053602051.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_053612553.1	4	Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis"
XP_053606144.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_053623539.1	13	Reactome: R-HSA-4341670;MetaCyc: PWY-6807;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2022857;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206308;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;Reactome: R-HSA-1660662	"Defective NEU1 causes sialidosis";"Xyloglucan degradation II (exoglucanase)";"Sialic acid metabolism";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Keratan sulfate degradation";"Sphingolipid metabolism";"Other glycan degradation";"MPS IV - Morquio syndrome B";"HS-GAG degradation";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism"
XP_053600119.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053604531.1	19	MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-7222;Reactome: R-HSA-380320;Reactome: R-HSA-380270;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7176;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-7227	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_053609004.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_053621936.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_053620293.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_053625528.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053621875.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-68884;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"MHC class II antigen presentation";"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053621798.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_053621081.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053618652.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053624054.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053622216.1	25	Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833	"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Gap junction assembly";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Cilium Assembly"
XP_053611164.1	20	Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-6804757;KEGG: 05170+2.7.11.1;Reactome: R-HSA-165159;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-3371571;Reactome: R-HSA-9639288;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Degradation";"Human immunodeficiency virus 1 infection";"mTOR signalling";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"CD28 dependent PI3K/Akt signaling";"HSF1-dependent transactivation";"Amino acids regulate mTORC1";"PI3K-Akt signaling pathway";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Human papillomavirus infection"
XP_053621113.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_053602397.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053601320.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053600471.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_053619175.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_053623205.1	2	KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_053604811.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_053625485.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_053602210.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725	"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_053616173.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053611991.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053615456.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053609109.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_053624159.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053600127.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053606120.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053620611.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053603151.1	7	Reactome: R-HSA-6798695;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-6737	"Neutrophil degranulation";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Starch degradation II";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch degradation V"
XP_053601930.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053624887.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_053618104.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_053606275.1	33	Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-68877;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-159231	"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"Mitotic Prometaphase";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_053603247.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_053617996.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053619846.1	6	MetaCyc: PWY-6362;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_053608394.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade"
XP_053618812.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_053613778.1	3	KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158;MetaCyc: PWY-8099	"Folate biosynthesis";"L-phenylalanine degradation V";"Tetrahydropteridine recycling"
XP_053612669.1	14	Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_053603473.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053607816.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053625900.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_053606995.1	4	Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48	"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_053618965.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_053622522.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053622341.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_053606922.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_053625522.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053626050.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053610255.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053603624.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053600153.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053612744.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053608087.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_053618410.1	2	Reactome: R-HSA-3000178;MetaCyc: PWY-7511	"ECM proteoglycans";"Protein ubiquitination"
XP_053623570.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_053603460.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_053620168.1	7	Reactome: R-HSA-71336;KEGG: 00030+3.1.1.31;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;MetaCyc: PWY-8004;MetaCyc: PWY-6906;MetaCyc: PWY-6855	"Pentose phosphate pathway";"Pentose phosphate pathway";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Entner-Doudoroff pathway I";"Chitin derivatives degradation";"Chitin degradation I (archaea)"
XP_053600966.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053619569.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_053608256.1	9	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053614991.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053602653.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_053619397.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053612031.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Neutrophil degranulation";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_053625226.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053621123.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-171007;Reactome: R-HSA-168638;Reactome: R-HSA-4420097	"mTOR signaling pathway";"DSCAM interactions";"p38MAPK events";"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway"
XP_053601310.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_053618756.1	9	KEGG: 00130+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00960+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00401+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00950+2.6.1.5	"Ubiquinone and other terpenoid-quinone biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Cysteine and methionine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Tyrosine catabolism";"Novobiocin biosynthesis";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis"
XP_053624503.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053622668.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_053625668.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_053605244.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053611158.1	20	KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-7007;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7854;MetaCyc: PWY-6920	"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)"
XP_053603075.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053620582.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_053624889.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_053604690.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_053610169.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_053600129.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053625430.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053600755.1	7	Reactome: R-HSA-70635;MetaCyc: PWY-46;MetaCyc: PWY-4984;MetaCyc: PWY-6922;KEGG: 00330+3.5.3.1;MetaCyc: PWY-31;KEGG: 00220+3.5.3.1	"Urea cycle";"Putrescine biosynthesis III";"Urea cycle";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Canavanine degradation";"Arginine biosynthesis"
XP_053612004.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053600294.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_053608632.1	5	KEGG: 00510+2.4.1.68;MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68;KEGG: 00513+2.4.1.68	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate";"Various types of N-glycan biosynthesis"
XP_053606918.1	3	MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531	"Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus"
XP_053624241.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053622840.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053609478.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_053611067.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053616207.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053615986.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053616954.1	12	Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-7385;KEGG: 00680+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00710+4.1.2.13	"Glycolysis";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms"
XP_053618801.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_053605627.1	10	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-201722;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Formation of the beta-catenin:TCF transactivating complex";"Human papillomavirus infection";"Human cytomegalovirus infection";"HATs acetylate histones";"Relaxin signaling pathway";"Ub-specific processing proteases";"PI3K-Akt signaling pathway"
XP_053615667.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_053599878.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_053619773.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053625111.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_053600509.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053625774.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_053599643.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053622083.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053616981.1	11	Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-69473	"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint"
XP_053617556.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_053624265.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_053613676.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053618772.1	24	Reactome: R-HSA-392451;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-163359;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-8964616;Reactome: R-HSA-418597;Reactome: R-HSA-500657;Reactome: R-HSA-6814122;Reactome: R-HSA-400042;Reactome: R-HSA-392170;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-418555;Reactome: R-HSA-202040;Reactome: R-HSA-418594	"G beta:gamma signalling through PI3Kgamma";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"Glucagon signaling in metabolic regulation";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through CDC42";"G alpha (z) signalling events";"Presynaptic function of Kainate receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 12";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"G alpha (s) signalling events";"G-protein activation";"G alpha (i) signalling events"
XP_053624123.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053600883.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_053617264.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_053607224.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053618834.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053614158.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_053619567.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_053609527.1	8	Reactome: R-HSA-606279;Reactome: R-HSA-141444;Reactome: R-HSA-6783310;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Fanconi Anemia Pathway";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_053607752.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_053611631.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053612517.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007	"Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy"
XP_053599566.1	3	Reactome: R-HSA-5626978;Reactome: R-HSA-193681;Reactome: R-HSA-1660662	"TNFR1-mediated ceramide production";"Ceramide signalling";"Glycosphingolipid metabolism"
XP_053611551.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_053615710.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053616766.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_053621738.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053625451.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_053601198.1	12	MetaCyc: PWY-6842;MetaCyc: PWY-2821;MetaCyc: PWY-1187;Reactome: R-HSA-71240;MetaCyc: PWY-6309;KEGG: 00380+2.6.1.7;KEGG: 00450+4.4.1.13;MetaCyc: PWY-801;MetaCyc: PWY-7901;KEGG: 00270+4.4.1.13;MetaCyc: PWY-601;MetaCyc: PWY-6936	"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from homomethionine";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Selenocompound metabolism";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tryptophan";"Seleno-amino acid biosynthesis (plants)"
XP_053615403.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053613283.1	7	Reactome: R-HSA-379716;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.15;Reactome: R-HSA-2408522;MetaCyc: PWY-5188	"Cytosolic tRNA aminoacylation";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_053602282.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_053606612.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_053603402.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053605337.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053608148.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-418594	"Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events"
XP_053599575.1	6	MetaCyc: PWY-6906;MetaCyc: PWY-7077;Reactome: R-HSA-446210;KEGG: 00052+3.5.1.25;KEGG: 00520+3.5.1.25;MetaCyc: PWY-7395	"Chitin derivatives degradation";"N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation"
XP_053615050.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053622594.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_053606994.1	4	Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I"
XP_053610643.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053618964.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053614418.1	17	Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053607366.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion"
XP_053610795.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_053610907.1	8	Reactome: R-HSA-8856828;Reactome: R-HSA-4641263;Reactome: R-HSA-4086398;Reactome: R-HSA-5340588;Reactome: R-HSA-373080;Reactome: R-HSA-4608870;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900	"Clathrin-mediated endocytosis";"Regulation of FZD by ubiquitination";"Ca2+ pathway";"RNF mutants show enhanced WNT signaling and proliferation";"Class B/2 (Secretin family receptors)";"Asymmetric localization of PCP proteins";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4"
XP_053601746.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053610254.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_053604677.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_053601454.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053623231.1	12	KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4	"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Plasmalogen degradation";"Linoleic acid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism"
XP_053610849.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053607596.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053618105.1	2	Reactome: R-HSA-389397;Reactome: R-HSA-416476	"Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events"
XP_053606325.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053621307.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053603800.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_053623489.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053618043.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053625160.1	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
XP_053611650.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053608395.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade"
XP_053619042.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_053603312.1	15	MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-7383;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5723;KEGG: 00010+2.7.1.40;MetaCyc: PWY-2221	"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Rubisco shunt";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_053608179.1	8	Reactome: R-HSA-983712;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"Photosynthesis";"ATP biosynthesis";"Oxidative phosphorylation";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_053610439.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_053604198.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053624996.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418594	"PKA activation";"Hedgehog 'off' state";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events"
XP_053625173.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_053624417.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_053609202.1	8	Reactome: R-HSA-5689880;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942	"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_053622484.1	3	MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807	"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III"
XP_053602708.1	14	MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-5981;MetaCyc: PWY-7411;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-5667;Reactome: R-HSA-1483166	"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA"
XP_053605708.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_053611093.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_053625484.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_053610396.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_053608203.1	16	Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579	"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"HATs acetylate histones";"Estrogen-dependent gene expression";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange"
XP_053601345.1	16	MetaCyc: PWY-5749;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.4;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5537;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.4;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403	"Itaconate degradation";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Citric acid cycle (TCA cycle)"
XP_053614321.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_053607765.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_053623369.1	52	Reactome: R-HSA-5578749;Reactome: R-HSA-167200;Reactome: R-HSA-203927;Reactome: R-HSA-76042;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-5617472;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-73980;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-5601884;Reactome: R-HSA-167242;Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-168325;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-76061;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-73863;Reactome: R-HSA-76071;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-72203;Reactome: R-HSA-6781823;Reactome: R-HSA-73780;Reactome: R-HSA-6782135;Reactome: R-HSA-749476;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-5250924;Reactome: R-HSA-167162;Reactome: R-HSA-167290;Reactome: R-HSA-1834949;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-76066;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-6781827	"Transcriptional regulation by small RNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Termination";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"Viral Messenger RNA Synthesis";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"mRNA Capping";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Chain Elongation";"Dual incision in TC-NER";"RNA Polymerase III Abortive And Retractive Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Pausing and recovery of HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_053620673.1	3	Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23	"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism"
XP_053619871.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053624556.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053599926.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_053607225.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053618835.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053607292.1	8	Reactome: R-HSA-6781827;Reactome: R-HSA-8948747;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation"
XP_053609359.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_053620848.1	5	Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695	"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation"
XP_053609211.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053617683.1	31	MetaCyc: PWY-8047;MetaCyc: PWYG-321;MetaCyc: PWY-5366;Reactome: R-HSA-163765;MetaCyc: PWY-5994;MetaCyc: PWY-7746;MetaCyc: PWY-4381;MetaCyc: PWY-7663;MetaCyc: PWY-6799;Reactome: R-HSA-199220;MetaCyc: PWY-5989;MetaCyc: PWY-5966-1;Reactome: R-HSA-75105;MetaCyc: PWY-5973;MetaCyc: PWY-7664;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;MetaCyc: PWY-7723;MetaCyc: PWY-6519;MetaCyc: PWY-8049;MetaCyc: PWY-7388;MetaCyc: PWY-5142;MetaCyc: PWY-8012;MetaCyc: PWY-5367;MetaCyc: PWY-5147;MetaCyc: PWY-7858;MetaCyc: PWY-6282;Reactome: R-HSA-9029558;MetaCyc: PWY-5971;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168	"Bryostatin biosynthesis";"";"Palmitoleate biosynthesis II (plants and bacteria)";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Vitamin B5 (pantothenate) metabolism";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"Cis-vaccenate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"Bacterial bioluminescence";"8-amino-7-oxononanoate biosynthesis I";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Mupirocin biosynthesis";"Petroselinate biosynthesis";"Oleate biosynthesis I (plants)";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_053612208.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape"
XP_053601382.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053605261.1	14	Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167246	"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript"
XP_053606581.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053602048.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_053601679.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053600781.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_053605048.1	182	Reactome: R-HSA-1253288;Reactome: R-HSA-5684264;Reactome: R-HSA-72764;Reactome: R-HSA-382556;Reactome: R-HSA-2559582;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-6804756;Reactome: R-HSA-6804757;Reactome: R-HSA-9633012;Reactome: R-HSA-937041;Reactome: R-HSA-6807004;Reactome: R-HSA-69481;Reactome: R-HSA-5357956;Reactome: R-HSA-8849469;Reactome: R-HSA-5656121;Reactome: R-HSA-3769402;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-9613829;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-6791226;Reactome: R-HSA-69231;Reactome: R-HSA-975163;Reactome: R-HSA-5632684;Reactome: R-HSA-168638;Reactome: R-HSA-5696394;Reactome: R-HSA-9033241;Reactome: R-HSA-2173796;Reactome: R-HSA-937042;Reactome: R-HSA-5696395;Reactome: R-HSA-8866654;Reactome: R-HSA-5675221;Reactome: R-HSA-209543;Reactome: R-HSA-168928;Reactome: R-HSA-3322077;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5689896;Reactome: R-HSA-72695;Reactome: R-HSA-8875360;Reactome: R-HSA-2122947;Reactome: R-HSA-5654726;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-110320;Reactome: R-HSA-5654727;Reactome: R-HSA-211733;Reactome: R-HSA-937039;Reactome: R-HSA-8852276;Reactome: R-HSA-6782210;Reactome: R-HSA-2979096;Reactome: R-HSA-912631;Reactome: R-HSA-5687128;Reactome: R-HSA-72706;Reactome: R-HSA-2559585;Reactome: R-HSA-4641257;Reactome: R-HSA-9013973;Reactome: R-HSA-9615710;Reactome: R-HSA-3134975;Reactome: R-HSA-69541;Reactome: R-HSA-5654732;Reactome: R-HSA-2173791;Reactome: R-HSA-2644606;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-9013507;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-2173788;Reactome: R-HSA-8948747;Reactome: R-HSA-1358803;Reactome: R-HSA-8951664;Reactome: R-HSA-182971;Reactome: R-HSA-2408557;Reactome: R-HSA-209560;Reactome: R-HSA-5678895;Reactome: R-HSA-8866652;Reactome: R-HSA-2173795;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-2122948;Reactome: R-HSA-6781827;Reactome: R-HSA-5693565;Reactome: R-HSA-6783310;Reactome: R-HSA-977225;Reactome: R-HSA-5689880;Reactome: R-HSA-9637628;Reactome: R-HSA-175474;Reactome: R-HSA-2672351;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-2565942;Reactome: R-HSA-5696400;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-9636383;Reactome: R-HSA-983168;Reactome: R-HSA-5685942;Reactome: R-HSA-1234176;Reactome: R-HSA-2894862;Reactome: R-HSA-1799339;Reactome: R-HSA-5358346;Reactome: R-HSA-6804760;Reactome: R-HSA-937072;Reactome: R-HSA-450321;Reactome: R-HSA-5205685;Reactome: R-HSA-110314;Reactome: R-HSA-174490;Reactome: R-HSA-5655862;Reactome: R-HSA-975144;Reactome: R-HSA-174084;Reactome: R-HSA-72702;Reactome: R-HSA-5357905;Reactome: R-HSA-187577;Reactome: R-HSA-162588;Reactome: R-HSA-8876493;Reactome: R-HSA-6781823;Reactome: R-HSA-4641263;Reactome: R-HSA-6782135;Reactome: R-HSA-5675482;Reactome: R-HSA-205043;Reactome: R-HSA-2559580;Reactome: R-HSA-174178;Reactome: R-HSA-917729;Reactome: R-HSA-5654733;Reactome: R-HSA-68827;Reactome: R-HSA-1295596;Reactome: R-HSA-400253;Reactome: R-HSA-975956;Reactome: R-HSA-450302;Reactome: R-HSA-975110;Reactome: R-HSA-69601;Reactome: R-HSA-201681;Reactome: R-HSA-8863795;Reactome: R-HSA-174048;Reactome: R-HSA-5689901;Reactome: R-HSA-901032;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-5656169;Reactome: R-HSA-9646399;Reactome: R-HSA-975957;Reactome: R-HSA-5689877;Reactome: R-HSA-168927;Reactome: R-HSA-2691232;Reactome: R-HSA-9014325;Reactome: R-HSA-936964;Reactome: R-HSA-5693607;Reactome: R-HSA-1236382;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-936440;Reactome: R-HSA-8856825;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-3785653;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-8856828;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-445989;Reactome: R-HSA-72689;Reactome: R-HSA-9645460;Reactome: R-HSA-917937;Reactome: R-HSA-4608870;Reactome: R-HSA-532668;Reactome: R-HSA-1169408;Reactome: R-HSA-179409;Reactome: R-HSA-174113	"Downregulation of ERBB4 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Eukaryotic Translation Termination";"ABC-family proteins mediated transport";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of RAS by GAPs";"UCH proteinases";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Regulation of TP53 Activity through Phosphorylation";"Regulation of TP53 Degradation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"IKK complex recruitment mediated by RIP1";"Negative regulation of MET activity";"G2/M Checkpoints";"TNFR1-induced NFkappaB signaling pathway";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Translesion synthesis by POLI";"Deactivation of the beta-catenin transactivating complex";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Chaperone Mediated Autophagy";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Major pathway of rRNA processing in the nucleolus and cytosol";"Cyclin D associated events in G1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Hedgehog 'on' state";"NOD1/2 Signaling Pathway";"DNA Damage Recognition in GG-NER";"Peroxisomal protein import";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"IRAK2 mediated activation of TAK1 complex";"Formation of Incision Complex in GG-NER";"E3 ubiquitin ligases ubiquitinate target proteins";"Negative regulation of MAPK pathway";"p75NTR recruits signalling complexes";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Glycogen synthesis";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Ovarian tumor domain proteases";"Formation of the ternary complex, and subsequently, the 43S complex";"InlB-mediated entry of Listeria monocytogenes into host cell";"NOTCH1 Intracellular Domain Regulates Transcription";"Negative regulation of FGFR1 signaling";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Translesion Synthesis by POLH";"Negative regulation of FGFR2 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"IRAK1 recruits IKK complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulation of signaling by CBL";"MAPK6/MAPK4 signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Oncogene Induced Senescence";"Degradation of AXIN";"TICAM1-dependent activation of IRF3/IRF7";"Late endosomal microautophagy";"Regulation of innate immune responses to cytosolic DNA";"Stabilization of p53";"Negative regulation of FGFR3 signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downregulation of TGF-beta receptor signaling";"Regulation of PTEN localization";"Downregulation of ERBB2:ERBB3 signaling";"Neddylation";"EGFR downregulation";"Selenocysteine synthesis";"NF-kB is activated and signals survival";"Defective CFTR causes cystic fibrosis";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Activated NOTCH1 Transmits Signal to the Nucleus";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Fanconi Anemia Pathway";"Amyloid fiber formation";"Ub-specific processing proteases";"Modulation by Mtb of host immune system";"Assembly Of The HIV Virion";"Stimuli-sensing channels";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of PLK1 Activity at G2/M Transition";"Dual Incision in GG-NER";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"Prevention of phagosomal-lysosomal fusion";"Antigen processing: Ubiquitination & Proteasome degradation";"HDR through Homologous Recombination (HRR)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SRP-dependent cotranslational protein targeting to membrane";"Hedgehog ligand biogenesis";"Regulation of TP53 Activity through Methylation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Pink/Parkin Mediated Mitophagy";"Recognition of DNA damage by PCNA-containing replication complex";"Membrane binding and targetting of GAG proteins";"Translesion synthesis by POLK";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ribosomal scanning and start codon recognition";"Regulation of TNFR1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Budding and maturation of HIV virion";"InlA-mediated entry of Listeria monocytogenes into host cells";"Formation of TC-NER Pre-Incision Complex";"Regulation of FZD by ubiquitination";"Dual incision in TC-NER";"Regulation of necroptotic cell death";"NRIF signals cell death from the nucleus";"Oxidative Stress Induced Senescence";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Negative regulation of FGFR4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Spry regulation of FGF signaling";"Circadian Clock";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"activated TAK1 mediates p38 MAPK activation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TCF dependent signaling in response to WNT";"Downregulation of ERBB2 signaling";"APC/C:Cdc20 mediated degradation of Cyclin B";"Metalloprotease DUBs";"ER Quality Control Compartment (ERQC)";"Peptide chain elongation";"Viral mRNA Translation";"Termination of translesion DNA synthesis";"Aggrephagy";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Josephin domain DUBs";"TICAM1, RIP1-mediated IKK complex recruitment";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Processing of DNA double-strand break ends";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Negative regulators of DDX58/IFIH1 signaling";"Cargo recognition for clathrin-mediated endocytosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Myoclonic epilepsy of Lafora";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Clathrin-mediated endocytosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Formation of a pool of free 40S subunits";"Alpha-protein kinase 1 signaling pathway";"Iron uptake and transport";"Asymmetric localization of PCP proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ISG15 antiviral mechanism";"APC-Cdc20 mediated degradation of Nek2A";"SCF-beta-TrCP mediated degradation of Emi1"
XP_053622981.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_053618150.1	2	KEGG: 04150+2.7.11.24;Reactome: R-HSA-5687128	"mTOR signaling pathway";"MAPK6/MAPK4 signaling"
XP_053614246.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053613368.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053625898.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_053625775.1	7	Reactome: R-HSA-203927;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-1655829;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-168333	"MicroRNA (miRNA) biogenesis";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_053624309.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053611605.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053617123.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs"
XP_053608318.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053613191.1	7	KEGG: 00550+2.7.8.13;MetaCyc: PWY-5265;KEGG: 00510+2.7.8.15;Reactome: R-HSA-446193;MetaCyc: PWY-6471;Reactome: R-HSA-4549356;MetaCyc: PWY-6470	"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis V (beta-lactam resistance)"
XP_053614213.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053623671.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_053604679.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination"
XP_053612143.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053600754.1	7	Reactome: R-HSA-70635;MetaCyc: PWY-4984;MetaCyc: PWY-46;KEGG: 00330+3.5.3.1;MetaCyc: PWY-6922;KEGG: 00220+3.5.3.1;MetaCyc: PWY-31	"Urea cycle";"Urea cycle";"Putrescine biosynthesis III";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine biosynthesis";"Canavanine degradation"
XP_053621309.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053614422.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_053602586.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_053612005.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053600295.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053610262.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-9609690;Reactome: R-HSA-3899300	"Regulation of TP53 Degradation";"HCMV Early Events";"SUMOylation of transcription cofactors"
XP_053600222.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_053610437.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_053616518.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053616955.1	10	MetaCyc: PWY-5891;Reactome: R-HSA-2142789;KEGG: 00130+2.1.1.163;MetaCyc: PWY-7996;MetaCyc: PWY-5890;MetaCyc: PWY-5892;MetaCyc: PWY-5849;MetaCyc: PWY-5844;MetaCyc: PWY-5839;MetaCyc: PWY-5895	"Menaquinol-11 biosynthesis";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-10 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-13 biosynthesis"
XP_053608177.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053616668.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053621556.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053615782.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053618296.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053600303.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053612782.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_053607972.1	10	Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape"
XP_053605245.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053617157.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053611585.1	6	Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-5620922	"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_053606266.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_053601006.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053611820.1	10	Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)"
XP_053609686.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053603074.1	3	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_053600025.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053617715.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_053617696.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053611434.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_053617406.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_053614311.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053599803.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053613482.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-390471	"Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053612202.1	13	Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857	"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"CS/DS degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Keratan sulfate degradation"
XP_053615202.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination"
XP_053609761.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053620842.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_053599735.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_053602711.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6433	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_053605370.1	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_053601630.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_053607298.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053611691.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053609313.1	10	MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842	"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Glutathione metabolism";"Glutathione-mediated detoxification II"
XP_053613362.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053603322.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_053624549.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053615323.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053612323.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_053600987.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053625787.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_053606980.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053603395.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053608312.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053624714.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053622358.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053621549.1	10	Reactome: R-HSA-9615017;Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-9022702;Reactome: R-HSA-427413;Reactome: R-HSA-9022699;Reactome: R-HSA-9022692;Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-3899300	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands";"NoRC negatively regulates rRNA expression";"MECP2 regulates neuronal receptors and channels";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"SUMOylation of transcription cofactors"
XP_053617316.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053614428.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_053614691.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_053608914.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053604468.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053610626.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053600666.1	9	Reactome: R-HSA-5218920;Reactome: R-HSA-194840;Reactome: R-HSA-2029482;Reactome: R-HSA-114604;Reactome: R-HSA-2871809;Reactome: R-HSA-193648;Reactome: R-HSA-2871796;Reactome: R-HSA-416482;Reactome: R-HSA-4420097	"VEGFR2 mediated vascular permeability";"Rho GTPase cycle";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade";"FCERI mediated Ca+2 mobilization";"NRAGE signals death through JNK";"FCERI mediated MAPK activation";"G alpha (12/13) signalling events";"VEGFA-VEGFR2 Pathway"
XP_053607022.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_053617343.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053618958.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_053605593.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053601723.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053611763.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053612091.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_053619337.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_053624866.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053612788.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053616479.1	5	KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6906;MetaCyc: PWY-6855;MetaCyc: PWY-5514	"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_053619282.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_053605030.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_053609693.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-159230	"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA"
XP_053611577.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_053611259.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053606622.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053624000.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_053608692.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053604388.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053623136.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053621427.1	5	Reactome: R-HSA-1482883;Reactome: R-HSA-6798695;KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20;Reactome: R-HSA-75109	"Acyl chain remodeling of DAG and TAG";"Neutrophil degranulation";"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_053608402.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_053607807.1	33	Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-180910;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-3232142;Reactome: R-HSA-9648025;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-159231	"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HCMV Early Events";"Mitotic Prometaphase";"SUMOylation of ubiquitinylation proteins";"EML4 and NUDC in mitotic spindle formation";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_053604757.1	20	Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-69473;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5693616;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5693607;Reactome: R-HSA-5696400;Reactome: R-HSA-6804756	"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"G2/M DNA damage checkpoint";"Polymerase switching";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processing of DNA double-strand break ends";"Dual Incision in GG-NER";"Regulation of TP53 Activity through Phosphorylation"
XP_053616216.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_053613296.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159231	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_053609897.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053607947.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053616534.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_053621732.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053614904.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053605288.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053611165.1	20	Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-6804757;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-389357;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;Reactome: R-HSA-165159;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-5218920;Reactome: R-HSA-3371571;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Degradation";"Macroautophagy";"Regulation of PTEN gene transcription";"CD28 dependent PI3K/Akt signaling";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"mTOR signalling";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Amino acids regulate mTORC1";"VEGFR2 mediated vascular permeability";"HSF1-dependent transactivation";"Relaxin signaling pathway";"PIP3 activates AKT signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection";"Thermogenesis"
XP_053620100.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053607603.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053607493.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053622535.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053623784.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_053606618.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053608074.1	15	Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-912446	"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination"
XP_053602288.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_053614086.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053614141.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_053624547.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053613381.1	3	KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693	"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism"
XP_053609116.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
XP_053602166.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_053616528.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_053615126.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053605166.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053623806.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-9609523;Reactome: R-HSA-1660661	"Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Sphingolipid de novo biosynthesis"
XP_053610872.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847	"Ub-specific processing proteases";"HATs acetylate histones"
XP_053625789.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053602953.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_053601685.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174	"Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_053614412.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_053617054.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053621740.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053608301.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053611931.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053621547.1	10	Reactome: R-HSA-3899300;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-9022538;Reactome: R-HSA-9022699;Reactome: R-HSA-427413;Reactome: R-HSA-9615017;Reactome: R-HSA-400206;Reactome: R-HSA-9022702;Reactome: R-HSA-8936459	"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates neuronal receptors and channels";"NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates transcription of neuronal ligands";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_053620071.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_053620414.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_053618191.1	5	Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32	"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism"
XP_053603318.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_053624874.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_053619339.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_053624258.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053606398.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053613835.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053619261.1	56	Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664	"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Separation of Sister Chromatids";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Neddylation"
XP_053615359.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053621055.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_053599943.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_053611904.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053611579.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_053617936.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053611257.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053612359.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007	"Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy"
XP_053619917.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_053619496.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053614165.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_053607809.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053613445.1	22	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5339716;Reactome: R-HSA-2500257;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-6811558;Reactome: R-HSA-5467348;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-141444;Reactome: R-HSA-5467337	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Resolution of Sister Chromatid Cohesion";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Truncations of AMER1 destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"RAF activation";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding"
XP_053604759.1	12	MetaCyc: PWY-6708;MetaCyc: PWY-7230;MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-5855;MetaCyc: PWY-7233;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5856;MetaCyc: PWY-5873;MetaCyc: PWY-5872;MetaCyc: PWY-5871;Reactome: R-HSA-2142789	"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis"
XP_053620520.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_053601505.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_053599916.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_053604270.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_053600841.1	20	Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-176187;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5696400	"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Polymerase switching";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of ATR in response to replication stress";"Translesion synthesis by POLK";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Dual Incision in GG-NER"
XP_053600912.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_053620091.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_053605644.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_053613724.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053601963.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053608387.1	30	KEGG: 04150+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-6804758;Reactome: R-HSA-198693;Reactome: R-HSA-9614399;Reactome: R-HSA-198323;Reactome: R-HSA-5628897;Reactome: R-HSA-6804757;Reactome: R-HSA-69656;Reactome: R-HSA-392451;Reactome: R-HSA-111447;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-8948751;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-8941332;Reactome: R-HSA-69202;Reactome: R-HSA-199418;Reactome: R-HSA-6804759;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8876198;Reactome: R-HSA-389513;Reactome: R-HSA-9634638;Reactome: R-HSA-5218920;Reactome: R-HSA-211163;Reactome: R-HSA-1358803;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Activity through Acetylation";"AKT phosphorylates targets in the nucleus";"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the cytosol";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Degradation";"Cyclin A:Cdk2-associated events at S phase entry";"G beta:gamma signalling through PI3Kgamma";"Activation of BAD and translocation to mitochondria";"Thermogenesis";"Human papillomavirus infection";"Regulation of PTEN stability and activity";"PI3K-Akt signaling pathway";"PIP3 activates AKT signaling";"RUNX2 regulates genes involved in cell migration";"Cyclin E associated events during G1/S transition";"Negative regulation of the PI3K/AKT network";"Regulation of TP53 Activity through Association with Co-factors";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"RAB GEFs exchange GTP for GDP on RABs";"CTLA4 inhibitory signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"VEGFR2 mediated vascular permeability";"AKT-mediated inactivation of FOXO1A";"Downregulation of ERBB2:ERBB3 signaling";"Relaxin signaling pathway"
XP_053605253.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053624894.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_053625626.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053615155.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053613996.1	6	KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433;MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632	"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_053613417.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_053614204.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053609233.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053612729.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053614957.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_053615729.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053619945.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053620969.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053619476.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_053602988.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053608232.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_053625041.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_053605988.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_053623542.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_053604290.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_053609544.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053608467.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053623308.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_053618427.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160	"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions"
XP_053613276.1	3	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_053603843.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053620202.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053612911.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_053611957.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053621641.1	4	MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;KEGG: 00270+1.13.11.20;Reactome: R-HSA-1614558	"Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Cysteine and methionine metabolism";"Degradation of cysteine and homocysteine"
XP_053617514.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053618866.1	5	Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-5221030	"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA"
XP_053615911.1	17	Reactome: R-HSA-9648025;Reactome: R-HSA-174178;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-68877;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2500257;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9022692;Reactome: R-HSA-6804756;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Thermogenesis";"Human papillomavirus infection";"Mitotic Prometaphase";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Resolution of Sister Chromatid Cohesion";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Regulation of MECP2 expression and activity";"Regulation of TP53 Activity through Phosphorylation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053608826.1	56	Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-9604323	"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling"
XP_053619217.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053624283.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_053602227.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_053601329.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053603433.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"HCMV Early Events";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_053626046.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053607915.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053607638.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_053607184.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053611231.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053610787.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724	"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription"
XP_053613307.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053606117.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053601044.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053607624.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_053624515.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053614671.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_053600056.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_053622463.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053612414.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Neddylation";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053608389.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_053621191.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053606280.1	29	Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-73779	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_053600287.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7601	"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_053605610.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053601731.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053602458.1	2	KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399	"Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_053612071.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_053617532.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7602	"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_053617652.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053624598.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053615885.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053609510.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053616499.1	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
XP_053600332.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_053602560.1	5	KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661	"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation"
XP_053615520.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053609673.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053612727.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053625470.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism"
XP_053603776.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_053608672.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation"
XP_053619180.1	4	Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72;MetaCyc: PWY-8026;Reactome: R-HSA-6807062	"Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol"
XP_053625856.1	1	Reactome: R-HSA-417973	"Adenosine P1 receptors"
XP_053599662.1	4	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation"
XP_053618429.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160	"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions"
XP_053608469.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_053609848.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053619384.1	11	Reactome: R-HSA-3656253;Reactome: R-HSA-202733;Reactome: R-HSA-3000170;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Cell surface interactions at the vascular wall";"Syndecan interactions";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1"
XP_053614367.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_053607736.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053615100.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053612100.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053615304.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053617676.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_053611959.1	5	Reactome: R-HSA-2426168;MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2;Reactome: R-HSA-191273;MetaCyc: PWY-922	"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway I"
XP_053619351.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053607278.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_053602229.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053601327.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053604704.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73779	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_053608214.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053611671.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053610789.1	18	MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;MetaCyc: PWY-7417	"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Plasmalogen degradation";"Linoleic acid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Synthesis of PA";"Arachidonic acid metabolism";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)"
XP_053600340.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_053600144.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053611487.1	5	Reactome: R-HSA-5658442;Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-186763;Reactome: R-HSA-5218921	"Regulation of RAS by GAPs";"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Downstream signal transduction";"VEGFR2 mediated cell proliferation"
XP_053599824.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053606119.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-390471;Reactome: R-HSA-983168	"Neddylation";"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053621598.1	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_053613264.1	4	Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4	"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053620126.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053600120.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053599518.1	7	Reactome: R-HSA-73817;MetaCyc: PWY-6596;MetaCyc: PWY-5695;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;KEGG: 00983+1.1.1.205;MetaCyc: PWY-7221	"Purine ribonucleoside monophosphate biosynthesis";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Purine metabolism";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis"
XP_053621105.1	6	MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-6922	"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-Ndelta-acetylornithine biosynthesis"
XP_053625281.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053599955.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_053604409.1	2	Reactome: R-HSA-1299308;Reactome: R-HSA-5576886	"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential"
XP_053621362.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053601893.1	24	Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-9648025	"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Kinesins";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"EML4 and NUDC in mitotic spindle formation"
XP_053600324.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_053614475.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053617410.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053607087.1	14	Reactome: R-HSA-196757;MetaCyc: PWY-3661-1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2161;KEGG: 00630+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-3661;MetaCyc: PWY-181;MetaCyc: PWY-3841;MetaCyc: PWY-1622;KEGG: 00260+2.1.2.1;KEGG: 00670+2.1.2.1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-5497	"Metabolism of folate and pterines";"Glycine betaine degradation II (mammalian)";"Methane metabolism";"Folate polyglutamylation";"Glyoxylate and dicarboxylate metabolism";"Folate transformations I";"Glycine betaine degradation I";"Photorespiration ";"Folate transformations II (plants)";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"One carbon pool by folate";"Cyanoamino acid metabolism";"Purine nucleobases degradation II (anaerobic)"
XP_053608197.1	16	Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"HATs acetylate histones";"Estrogen-dependent gene expression"
XP_053610209.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053602099.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_053614913.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053610815.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053625396.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_053606471.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053605217.1	8	MetaCyc: PWY-7734;MetaCyc: PWY-5651;MetaCyc: PWY-7717;MetaCyc: PWY-6309;MetaCyc: PWY-7765;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7733;KEGG: 00380+3.5.1.9	"Quinoxaline-2-carboxylate biosynthesis";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Glyoxylate and dicarboxylate metabolism";"3-hydroxyquinaldate biosynthesis";"Tryptophan metabolism"
XP_053601319.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053620899.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053610173.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_053599668.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053617524.1	12	MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00680+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00030+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861	"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_053612908.1	12	Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-977225	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Amyloid fiber formation"
XP_053607564.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053601147.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_053626023.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway"
XP_053602961.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-76042	"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_053612544.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_053606153.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053620693.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_053618417.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_053605850.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053604251.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053602476.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_053623311.1	7	KEGG: 00310+2.3.1.61;KEGG: 00380+2.3.1.61;MetaCyc: PWY-5084;Reactome: R-HSA-71403;Reactome: R-HSA-389661;KEGG: 00020+2.3.1.61;Reactome: R-HSA-71064	"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citric acid cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine catabolism"
XP_053613427.1	4	KEGG: 00510+2.4.1.260;KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_053599832.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053624482.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053625566.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409	"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis"
XP_053617104.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053610451.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053603232.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053608764.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053603387.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-456926	"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_053619253.1	24	Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332	"HCMV Early Events";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin"
XP_053625795.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
XP_053600707.1	5	Reactome: R-HSA-1912420;Reactome: R-HSA-1912399;Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912408	"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation"
XP_053625616.1	3	Reactome: R-HSA-8939243;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence"
XP_053604893.1	5	Reactome: R-HSA-111458;Reactome: R-HSA-9627069;KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112;MetaCyc: PWY-4361	"Formation of apoptosome";"Regulation of the apoptosome activity";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_053625878.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053611946.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053625722.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053613171.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053619644.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053616255.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053622643.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053621964.1	3	KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_053610594.1	8	Reactome: R-HSA-9636467;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-77387;Reactome: R-HSA-167590;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Blockage of phagosome acidification";"Transferrin endocytosis and recycling";"Ion channel transport";"Nef Mediated CD8 Down-regulation";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_053616794.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053599814.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627	"Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_053606129.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053604407.1	2	Reactome: R-HSA-1299308;Reactome: R-HSA-5576886	"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential"
XP_053621381.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053600918.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_053625437.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_053606755.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053609753.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053607089.1	14	MetaCyc: PWY-2161;MetaCyc: PWY-3661-1;KEGG: 00680+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-5497;KEGG: 00260+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-3841;KEGG: 00670+2.1.2.1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-3661;KEGG: 00630+2.1.2.1;MetaCyc: PWY-2201	"Folate polyglutamylation";"Glycine betaine degradation II (mammalian)";"Methane metabolism";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Folate transformations II (plants)";"One carbon pool by folate";"Cyanoamino acid metabolism";"Photorespiration ";"Glycine betaine degradation I";"Glyoxylate and dicarboxylate metabolism";"Folate transformations I"
XP_053606372.1	4	Reactome: R-HSA-156581;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-6782315	"Methylation";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"tRNA modification in the nucleus and cytosol"
XP_053620005.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053610954.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053608199.1	16	Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579	"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"HATs acetylate histones";"Estrogen-dependent gene expression";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange"
XP_053610207.1	13	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Thermogenesis";"Human papillomavirus infection";"Signaling by BRAF and RAF fusions";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053622193.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_053609269.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_053606689.1	8	Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-4551638;Reactome: R-HSA-8943724;Reactome: R-HSA-212300	"HCMV Early Events";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"SUMOylation of chromatin organization proteins";"Regulation of PTEN gene transcription";"PRC2 methylates histones and DNA"
XP_053601317.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053602351.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_053611073.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_053601571.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053624703.1	10	MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00562+5.3.1.1;KEGG: 00051+5.3.1.1;KEGG: 00710+5.3.1.1;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-7003;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70171	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Inositol phosphate metabolism";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Glycolysis"
XP_053611784.1	2	Reactome: R-HSA-442982;Reactome: R-HSA-5673001	"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade"
XP_053623548.1	7	MetaCyc: PWY-5697;MetaCyc: PWY-5686;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5698;MetaCyc: PWY-7791;KEGG: 00230+3.5.2.5;MetaCyc: PWY-7790	"Allantoin degradation to ureidoglycolate I (urea producing)";"UMP biosynthesis I";"Pyrimidine metabolism";"Allantoin degradation to ureidoglycolate II (ammonia producing)";"UMP biosynthesis III";"Purine metabolism";"UMP biosynthesis II"
XP_053607868.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053615879.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053609100.1	3	MetaCyc: PWY-7999;Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4	"Vitamin K-epoxide cycle";"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_053612879.1	17	MetaCyc: PWY-7227;MetaCyc: PWY-7197;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7176;MetaCyc: PWY-7226;MetaCyc: PWY-7222;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7221	"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis"
XP_053608238.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_053601149.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_053621835.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_053615848.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053623579.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-76042	"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_053614073.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_053609902.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053618419.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160	"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions"
XP_053613055.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053620221.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-8953750	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6"
XP_053607632.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_053607552.1	7	MetaCyc: PWY-7456;MetaCyc: PWY-7586;Reactome: R-HSA-446205;KEGG: 00051+5.4.2.8;MetaCyc: PWY-882;MetaCyc: PWY-5659;KEGG: 00520+5.4.2.8	"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_053612673.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053611333.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_053604149.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_053615717.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053612510.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_053609885.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_053604939.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_053613740.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_053603389.1	6	Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-399997	"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion"
XP_053606974.1	4	MetaCyc: PWY-2781;Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315	"Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion";"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol"
XP_053625574.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_053600709.1	5	Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-5083630;Reactome: R-HSA-1912399;Reactome: R-HSA-1912420	"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Processing in Golgi"
XP_053606509.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053624952.1	11	MetaCyc: PWY-381;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-5675;MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2;Reactome: R-HSA-210455;Reactome: R-HSA-8964539	"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Nitrate reduction V (assimilatory)";"L-glutamine biosynthesis III";"Arginine biosynthesis";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glutamate and glutamine metabolism"
XP_053616575.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053610775.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_053604020.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_053605330.1	3	Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271	"GDP-fucose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_053617482.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053608765.1	56	Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-983168	"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053601670.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053618887.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053615057.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053606218.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_053625794.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5626467	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs"
XP_053601513.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053611011.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_053618159.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053604088.1	57	Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-6798695;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Degradation of DVL";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation"
XP_053624812.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_053619645.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053620669.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053621965.1	3	KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_053616254.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053613406.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053610595.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-167590;Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-917977;Reactome: R-HSA-9636467	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation";"Ion channel transport";"Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling";"Blockage of phagosome acidification"
XP_053616616.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053602128.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_053602101.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_053610766.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053616566.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_053619118.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053609350.1	18	KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482801;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416;Reactome: R-HSA-1482925	"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG"
XP_053611623.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_053601663.1	4	Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-5579026	"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_053619037.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_053623152.1	11	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"E3 ubiquitin ligases ubiquitinate target proteins";"mTOR signaling pathway";"IRF3-mediated induction of type I IFN";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA"
XP_053609588.1	4	Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-389661;Reactome: R-HSA-77289	"Respiratory electron transport";"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation"
XP_053613343.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-204005	"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport"
XP_053619377.1	11	Reactome: R-HSA-3656253;Reactome: R-HSA-1971475;Reactome: R-HSA-3000170;Reactome: R-HSA-202733;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis";"Syndecan interactions";"Cell surface interactions at the vascular wall";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation"
XP_053609013.1	6	Reactome: R-HSA-114516;Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900	"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4"
XP_053602063.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_053618326.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_053612561.1	7	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-140837;Reactome: R-HSA-416476;Reactome: R-HSA-114608;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"Intrinsic Pathway of Fibrin Clot Formation";"G alpha (q) signalling events";"Platelet degranulation";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_053601791.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053606106.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_053607924.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053621131.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053602508.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053605063.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8875656	"RAB geranylgeranylation";"MET receptor recycling"
XP_053615023.1	2	Reactome: R-HSA-191859;Reactome: R-HSA-6807505	"snRNP Assembly";"RNA polymerase II transcribes snRNA genes"
XP_053617880.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_053623845.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053607565.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053614742.1	7	Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-110331;Reactome: R-HSA-171306	"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged purine";"Packaging Of Telomere Ends"
XP_053601869.1	32	Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-8851708;Reactome: R-HSA-9018519;Reactome: R-HSA-6796648;Reactome: R-HSA-72163;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-168325;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167238	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Signaling by FGFR2 IIIa TM";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation"
XP_053611829.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_053621104.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-113507	"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation"
XP_053604670.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053599954.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_053607938.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053614011.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053608741.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_053600274.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_053600325.1	3	Reactome: R-HSA-71262;KEGG: 00310+1.14.11.8;MetaCyc: PWY-6100	"Carnitine synthesis";"Lysine degradation";"L-carnitine biosynthesis"
XP_053603807.1	3	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409;KEGG: 00860+1.16.3.1	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis";"Porphyrin and chlorophyll metabolism"
XP_053600858.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_053612611.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_053622167.1	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_053614474.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_053614183.1	7	Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_053604546.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053619661.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053601230.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053606781.1	6	Reactome: R-HSA-111367;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-77588	"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_053615602.1	3	KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;MetaCyc: PWY-6987	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_053625575.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi"
XP_053612492.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053618157.1	2	KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217	"Purine metabolism";"Purine salvage"
XP_053599962.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_053615059.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053623033.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053618241.1	5	KEGG: 00072+4.1.3.4;KEGG: 00650+4.1.3.4;KEGG: 00280+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00281+4.1.3.4	"Synthesis and degradation of ketone bodies";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Mevalonate degradation";"Geraniol degradation"
XP_053611853.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053611466.1	3	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843	"Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_053623905.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053613054.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053610442.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_053606098.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053619348.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053609884.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053619379.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;MetaCyc: PWY-7980;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"ATP biosynthesis";"Transferrin endocytosis and recycling";"Photosynthesis";"Oxidative phosphorylation"
XP_053600601.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_053613081.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_053608163.1	31	MetaCyc: PWY-7746;Reactome: R-HSA-163765;MetaCyc: PWY-5994;MetaCyc: PWYG-321;MetaCyc: PWY-5366;MetaCyc: PWY-8047;MetaCyc: PWY-5966-1;Reactome: R-HSA-75105;MetaCyc: PWY-5973;Reactome: R-HSA-199220;MetaCyc: PWY-5989;MetaCyc: PWY-6799;MetaCyc: PWY-4381;MetaCyc: PWY-7663;MetaCyc: PWY-7388;MetaCyc: PWY-5142;MetaCyc: PWY-7723;MetaCyc: PWY-6519;MetaCyc: PWY-8049;MetaCyc: PWY-7664;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168;MetaCyc: PWY-5971;MetaCyc: PWY-5147;MetaCyc: PWY-7858;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-8012;MetaCyc: PWY-5367	"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"";"Palmitoleate biosynthesis II (plants and bacteria)";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"Cis-vaccenate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bacterial bioluminescence";"8-amino-7-oxononanoate biosynthesis I";"Pederin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis I (plants)";"(5Z)-dodecenoate biosynthesis II";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mupirocin biosynthesis";"Petroselinate biosynthesis"
XP_053604426.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053611785.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-442982	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_053610226.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_053600266.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053619122.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053611827.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053615890.1	6	MetaCyc: PWY-7442;MetaCyc: PWY-6606;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;Reactome: R-HSA-74259;MetaCyc: PWY-5497	"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Purine metabolism";"Purine catabolism";"Purine nucleobases degradation II (anaerobic)"
XP_053601867.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053618683.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053616847.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053624801.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-2173788	"UCH proteinases";"Downregulation of TGF-beta receptor signaling"
XP_053600188.1	5	MetaCyc: PWY-6129;Reactome: R-HSA-4755579;Reactome: R-HSA-193048;Reactome: R-HSA-446199;KEGG: 00510+1.3.1.94	"Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Androgen biosynthesis";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis"
XP_053624772.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_053610430.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_053620004.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053617703.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053605441.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination"
XP_053616437.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_053599968.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18	"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053602661.1	25	Reactome: R-HSA-8941332;Reactome: R-HSA-8939236;Reactome: R-HSA-8941284;Reactome: R-HSA-8939902;Reactome: R-HSA-8940973;Reactome: R-HSA-8939242;Reactome: R-HSA-9018519;Reactome: R-HSA-8941326;Reactome: R-HSA-9616222;Reactome: R-HSA-8939246;Reactome: R-HSA-8939256;Reactome: R-HSA-8949275;Reactome: R-HSA-8941858;Reactome: R-HSA-8939247;Reactome: R-HSA-8936459;Reactome: R-HSA-8878166;Reactome: R-HSA-8931987;Reactome: R-HSA-8934593;Reactome: R-HSA-8951936;Reactome: R-HSA-8951911;Reactome: R-HSA-8939243;Reactome: R-HSA-8935964;Reactome: R-HSA-8941333;Reactome: R-HSA-8939245;Reactome: R-HSA-8877330	"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates chondrocyte maturation";"Regulation of RUNX2 expression and activity";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"Estrogen-dependent gene expression";"RUNX2 regulates bone development";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX3 Regulates Immune Response and Cell Migration";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by RUNX2";"RUNX1 regulates estrogen receptor mediated transcription";"Regulation of RUNX1 Expression and Activity";"RUNX3 regulates p14-ARF";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates expression of components of tight junctions";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)"
XP_053607692.1	5	Reactome: R-HSA-9033500;MetaCyc: PWY-7782;KEGG: 00565+2.5.1.26;Reactome: R-HSA-75896;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Plasmalogen biosynthesis";"Peroxisomal protein import"
XP_053625780.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053605206.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053625587.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
XP_053610096.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053603486.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_053617665.1	3	KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693	"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism"
XP_053601103.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_053614008.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053624236.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053604061.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053624514.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053613326.1	17	Reactome: R-HSA-176412;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-179409	"Phosphorylation of the APC/C";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A"
XP_053604248.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053611819.1	10	Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607	"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends"
XP_053614570.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_053617515.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053603012.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053614646.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_053609023.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053608095.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_053619521.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053620109.1	33	Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-69656;Reactome: R-HSA-76042;Reactome: R-HSA-69202;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-8939236;Reactome: R-HSA-69231;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-5696395;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-69273;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-6781823;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-427413;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-167172	"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"Cyclin A/B1/B2 associated events during G2/M transition";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome"
XP_053610448.1	9	KEGG: 00010+1.2.1.12;MetaCyc: PWY-7003;MetaCyc: PWY-5484;MetaCyc: PWY-6901;Reactome: R-HSA-70263;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-1042	"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)"
XP_053607914.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053622064.1	6	MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_053599535.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053602377.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7601	"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_053615588.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-204005	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport"
XP_053609391.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053615154.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053601248.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053605037.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-388844	"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_053612588.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053616041.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053625943.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_053611570.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_053614205.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053611777.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-442982	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_053619944.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053617026.1	9	Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-9656256;Reactome: R-HSA-110330;Reactome: R-HSA-5649702;Reactome: R-HSA-9656255;Reactome: R-HSA-110331;Reactome: R-HSA-9657050	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Defective OGG1 Substrate Processing";"Recognition and association of DNA glycosylase with site containing an affected purine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Substrate Binding";"Cleavage of the damaged purine";"Defective OGG1 Localization"
XP_053625607.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_053622916.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053625497.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-6798695;Reactome: R-HSA-446203;Reactome: R-HSA-879415	"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation";"Asparagine N-linked glycosylation";"Advanced glycosylation endproduct receptor signaling"
XP_053611646.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053609545.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_053619128.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053609168.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053620529.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053623271.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053613159.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053600182.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_053621749.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053624822.1	12	Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-429947;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72662;Reactome: R-HSA-166208;Reactome: R-HSA-156827	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053605645.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_053606666.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053616626.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053614393.1	52	Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-76061;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-203927;Reactome: R-HSA-167200;Reactome: R-HSA-5578749;Reactome: R-HSA-5617472;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-73980;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-5601884;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-112382;Reactome: R-HSA-1834949;Reactome: R-HSA-73762;Reactome: R-HSA-76066;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-6781827;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-76071;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-72203;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-73780;Reactome: R-HSA-6781823;Reactome: R-HSA-167290;Reactome: R-HSA-5250924;Reactome: R-HSA-167162;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-749476	"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"MicroRNA (miRNA) biogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcriptional regulation by small RNAs";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"Formation of RNA Pol II elongation complex";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Estrogen-dependent gene expression";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Chain Elongation";"Formation of TC-NER Pre-Incision Complex";"Pausing and recovery of HIV elongation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053603765.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053604103.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053618696.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_053602793.1	26	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-389960;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"Mitotic Prometaphase";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"Formation of tubulin folding intermediates by CCT/TriC";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs"
XP_053611563.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_053624895.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_053617641.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053621236.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053605793.1	15	Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-3769402;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-5689896;Reactome: R-HSA-5358747;Reactome: R-HSA-111465;Reactome: R-HSA-5467333;Reactome: R-HSA-195253	"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"S33 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"APC truncation mutants are not K63 polyubiquitinated";"Degradation of beta-catenin by the destruction complex"
XP_053616268.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_053624778.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-432040	"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_053606228.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053619441.1	9	KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52	"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Other glycan degradation"
XP_053603292.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191;KEGG: 00564+3.1.1.7	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC";"Glycerophospholipid metabolism"
XP_053625076.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_053622076.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053613683.1	5	Reactome: R-HSA-5358346;Reactome: R-HSA-901032;MetaCyc: PWY-7511;Reactome: R-HSA-381038;Reactome: R-HSA-5362768	"Hedgehog ligand biogenesis";"ER Quality Control Compartment (ERQC)";"Protein ubiquitination";"XBP1(S) activates chaperone genes";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_053600145.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053616728.1	7	KEGG: 00620+2.3.3.9;MetaCyc: PWY-7295;KEGG: 00630+2.3.3.9;MetaCyc: PWY-7118;MetaCyc: PWY-7854;MetaCyc: PWY-6969;MetaCyc: PWY-7294	"Pyruvate metabolism";"L-arabinose degradation IV";"Glyoxylate and dicarboxylate metabolism";"Chitin degradation to ethanol";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"D-xylose degradation IV"
XP_053617488.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053599892.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_053606989.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_053599825.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053604082.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053624818.1	12	Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-72662	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"ISG15 antiviral mechanism";"Translation initiation complex formation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"
XP_053603374.1	5	Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-201722	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex"
XP_053610654.1	3	KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684	"Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism"
XP_053603163.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053607940.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053618081.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_053615162.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053621652.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053618146.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053615305.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053604443.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_053611817.1	10	Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-69473	"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint"
XP_053623584.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_053623158.1	7	MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism"
XP_053610243.1	5	Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5620922;Reactome: R-HSA-5610787;Reactome: R-HSA-5632684	"Activation of SMO";"Class B/2 (Secretin family receptors)";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'off' state";"Hedgehog 'on' state"
XP_053625735.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_053611748.1	10	MetaCyc: PWY-5497;MetaCyc: PWY-6613;MetaCyc: PWY-5030;MetaCyc: PWY-3841;MetaCyc: PWY-7909;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-1722;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9	"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations I";"One carbon pool by folate"
XP_053600450.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053601559.1	12	MetaCyc: PWY-1187;MetaCyc: PWY-6842;MetaCyc: PWY-2821;MetaCyc: PWY-7901;MetaCyc: PWY-801;KEGG: 00450+4.4.1.13;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6936;KEGG: 00270+4.4.1.13;MetaCyc: PWY-601;MetaCyc: PWY-6309;Reactome: R-HSA-71240	"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"Selenocompound metabolism";"Tryptophan metabolism";"Seleno-amino acid biosynthesis (plants)";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tryptophan";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism"
XP_053607301.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053617368.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053610477.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-2871796;Reactome: R-HSA-450321	"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_053615884.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053608137.1	10	Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)"
XP_053602039.1	13	MetaCyc: PWY-6969;MetaCyc: PWY-5537;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_053611779.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-442982	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_053613068.1	5	MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621	"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine catabolism"
XP_053619910.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_053614748.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-418594	"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"G alpha (i) signalling events"
XP_053622052.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_053619385.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053623551.1	7	MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00230+3.5.2.5;MetaCyc: PWY-5698;MetaCyc: PWY-5697;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5686	"UMP biosynthesis II";"UMP biosynthesis III";"Purine metabolism";"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Allantoin degradation to ureidoglycolate I (urea producing)";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_053601416.1	3	Reactome: R-HSA-6799198;Reactome: R-HSA-1268020;Reactome: R-HSA-611105	"Complex I biogenesis";"Mitochondrial protein import";"Respiratory electron transport"
XP_053620527.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_053602920.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053603034.1	18	KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7117;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-7115;MetaCyc: PWY-5913;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00330+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7383	"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Cysteine and methionine metabolism";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Alanine, aspartate and glutamate metabolism";"(R)-cysteate degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)";"Arginine biosynthesis";"Sulfolactate degradation III";"Arginine and proline metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Novobiocin biosynthesis";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_053621747.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053610121.1	13	Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-6804757;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-5218920;Reactome: R-HSA-9639288;Reactome: R-HSA-1257604;Reactome: R-HSA-380972	"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Macroautophagy";"Regulation of TP53 Degradation";"TP53 Regulates Metabolic Genes";"mTOR signalling";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"VEGFR2 mediated vascular permeability";"Amino acids regulate mTORC1";"PIP3 activates AKT signaling";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_053615415.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053600161.1	7	Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-6798695;Reactome: R-HSA-389960	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Neutrophil degranulation";"Formation of tubulin folding intermediates by CCT/TriC"
XP_053613157.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053607932.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_053614196.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053612973.1	18	KEGG: 00270+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-5392;MetaCyc: PWY-1622;MetaCyc: PWY-6969;MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-7115;Reactome: R-HSA-70263;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00720+1.1.1.37	"Cysteine and methionine metabolism";"Methane metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Reductive TCA cycle II";"Formaldehyde assimilation I (serine pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes"
XP_053613241.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_053616463.1	20	Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-69473;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5693616;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5693607;Reactome: R-HSA-5696400;Reactome: R-HSA-6804756	"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"G2/M DNA damage checkpoint";"Polymerase switching";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processing of DNA double-strand break ends";"Dual Incision in GG-NER";"Regulation of TP53 Activity through Phosphorylation"
XP_053623604.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_053604306.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_053622336.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_053621818.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"