Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_028895050.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_011188135.1	1	Reactome: R-HSA-416476	"G alpha (q) signalling events"
XP_011188336.1	37	Reactome: R-HSA-4551638;Reactome: R-HSA-141444;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-9639288;Reactome: R-HSA-983170;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-4570464;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-204005;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-165054	"SUMOylation of chromatin organization proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"Amino acids regulate mTORC1";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"SUMOylation of RNA binding proteins";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Mitotic Prometaphase";"COPII-mediated vesicle transport";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA"
XP_011181745.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_028899055.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_011186912.1	11	MetaCyc: PWY-5913;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-6549;MetaCyc: PWY-7124;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-7268;MetaCyc: PWY-6969	"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"L-glutamine biosynthesis III";"Ethylene biosynthesis V (engineered)";"Glutathione metabolism";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_054081261.1	10	Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-5684264;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590	"Activation of NF-kappaB in B cells";"Neddylation";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling"
XP_054086809.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_028900455.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_054087791.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_028896712.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054083539.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_011180173.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054085296.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054088178.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-1538133	"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"G0 and Early G1"
XP_011183116.1	5	KEGG: 00513+2.4.1.68;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68;KEGG: 00533+2.4.1.68	"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate"
XP_011196068.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_011186890.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_054087425.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_054084438.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011177004.1	3	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256;Reactome: R-HSA-936837	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Ion transport by P-type ATPases"
XP_011190896.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054082500.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054090584.1	7	Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105	"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation"
XP_011183535.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_011187331.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054090145.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011193016.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_054088093.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-432040	"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (z) signalling events";"G alpha (s) signalling events";"Purine metabolism";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_011196910.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_011193949.1	4	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_028893645.1	22	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-389513	"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling"
XP_011176484.1	3	Reactome: R-HSA-5628897;Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_011193189.2	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054089469.1	8	KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;MetaCyc: PWY-6609;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1	"Purine metabolism";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Surfactant metabolism";"Adenine and adenosine salvage V";"Purine salvage";"Purine deoxyribonucleosides degradation II"
XP_054088796.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_028901514.1	14	MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-8051	"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Synthesis of PA";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I"
XP_011187762.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_028899181.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054081798.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis"
XP_054090413.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation"
XP_011185070.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054089722.1	4	KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"HATs acetylate histones"
XP_054090320.1	8	Reactome: R-HSA-163754;Reactome: R-HSA-6791462;Reactome: R-HSA-6791055;MetaCyc: PWY-1861;Reactome: R-HSA-8950505;Reactome: R-HSA-71336;KEGG: 00030+2.2.1.2;MetaCyc: PWY-5723	"Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Pentose phosphate pathway";"Pentose phosphate pathway";"Rubisco shunt"
XP_054084028.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_011176467.1	5	Reactome: R-HSA-70895;KEGG: 00640+1.2.4.4;KEGG: 00280+1.2.4.4;MetaCyc: PWY-5046;Reactome: R-HSA-389661	"Branched-chain amino acid catabolism";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation"
XP_054087035.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054091076.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054089983.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054087418.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_011182728.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_054084479.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_011181638.1	24	Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-190861	"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Aggrephagy";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"RHO GTPases Activate Formins";"Gap junction assembly"
XP_054084473.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054084596.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_054086114.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_028901835.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_054089989.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_011189810.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-180746	"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein"
XP_028894916.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_011189797.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_011184552.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_028896396.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_011182476.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_054081227.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_028898520.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_011184709.1	3	KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158;MetaCyc: PWY-8099	"Folate biosynthesis";"L-phenylalanine degradation V";"Tetrahydropteridine recycling"
XP_011196023.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011177121.2	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_054081906.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_054087195.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011196931.2	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_011177188.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_011176506.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-5628897	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes"
XP_028894909.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_054088099.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-170670	"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Purine metabolism";"G alpha (s) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway"
XP_011180259.1	5	Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-2173789;Reactome: R-HSA-8856825	"UCH proteinases";"Neddylation";"Iron uptake and transport";"TGF-beta receptor signaling activates SMADs";"Cargo recognition for clathrin-mediated endocytosis"
XP_011178815.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011193765.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054088822.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_054088048.1	12	Reactome: R-HSA-451308;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-438066	"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Long-term potentiation";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_011177999.2	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054082949.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_028897640.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_011179476.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_011182544.2	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_054085806.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-432722;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440	"Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network"
XP_028901211.1	9	MetaCyc: PWY-5667;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;MetaCyc: PWY-6118;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.94;Reactome: R-HSA-1483166;MetaCyc: PWY-7902;MetaCyc: PWY-7411	"CDP-diacylglycerol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Synthesis of PA";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)"
XP_011187530.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_028902130.2	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_011179593.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_011178538.2	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_011180179.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_011187988.2	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_011185126.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054083975.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_011192190.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_011190143.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_011196433.2	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_011179111.1	19	MetaCyc: PWY-7176;Reactome: R-HSA-380320;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7220;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7210;Reactome: R-HSA-380270;MetaCyc: PWY-7198;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197	"UTP and CTP de novo biosynthesis";"Recruitment of NuMA to mitotic centrosomes";"Purine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation"
XP_028894862.2	2	Reactome: R-HSA-204626;MetaCyc: PWY-5905	"Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis"
XP_011191137.2	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_054085368.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_011178126.2	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_054090521.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_011185902.1	7	Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-2151201;Reactome: R-HSA-1268020	"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"ATP biosynthesis";"Photosynthesis";"Cristae formation";"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial protein import"
XP_011184330.1	7	KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-3000170;Reactome: R-HSA-212676;Reactome: R-HSA-373753;Reactome: R-HSA-6794361	"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Syndecan interactions";"Dopamine Neurotransmitter Release Cycle";"Nephrin family interactions";"Neurexins and neuroligins"
XP_028896360.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054087100.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_011189985.1	23	Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-456926;Reactome: R-HSA-8964315;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-202040;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-6814122;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-400042;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-8964616	"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through BTK";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"G-protein activation";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through CDC42"
XP_028896080.1	6	MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143	"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis"
XP_054090741.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_011191775.1	8	MetaCyc: PWY-7179;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;MetaCyc: PWY-6609	"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Purine metabolism";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Surfactant metabolism";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III"
XP_054092109.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_054083030.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_028896762.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_028896677.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_011184732.2	8	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_054084946.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_054087429.1	6	Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-73856	"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"RNA Polymerase II Transcription Termination"
XP_054084019.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011186672.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011185260.2	17	MetaCyc: PWY-7224;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7221;MetaCyc: PWY-6545;MetaCyc: PWY-7220;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7184;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7198	"Purine deoxyribonucleosides salvage";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_011176918.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054084630.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054088752.1	23	Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-456926;Reactome: R-HSA-8964315;Reactome: R-HSA-9009391;Reactome: R-HSA-428930;Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-6814122;Reactome: R-HSA-381676;Reactome: R-HSA-202040;Reactome: R-HSA-418217	"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through BTK";"Extra-nuclear estrogen signaling";"Thromboxane signalling through TP receptor";"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G-protein activation";"G beta:gamma signalling through PLC beta"
XP_011190584.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_011191707.3	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_054083973.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;MetaCyc: PWY-7511;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_011184101.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_054090860.1	4	Reactome: R-HSA-1655829;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-381033	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones"
XP_011188258.1	3	Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7	"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism"
XP_011196889.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054090073.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011191076.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_011194055.2	5	KEGG: 00230+6.3.5.3;MetaCyc: PWY-6277;MetaCyc: PWY-6121;Reactome: R-HSA-73817;MetaCyc: PWY-6122	"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_054082728.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_054084006.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_054088957.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011190263.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011186784.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_011178323.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_028894508.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_028900459.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_011182222.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_028895300.2	6	KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-7900;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_054082599.1	12	Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.7.4;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.1.25;Reactome: R-HSA-2408550;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-5340;MetaCyc: PWY-6932;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278	"Transport and synthesis of PAPS";"Purine metabolism";"Sulfur metabolism";"Sulfur metabolism";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenocompound metabolism";"Assimilatory sulfate reduction III";"Sulfate activation for sulfonation";"Selenate reduction";"Monobactam biosynthesis";"Sulfite oxidation III"
XP_054082807.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_028896225.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148	"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_011183306.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1679131;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Neutrophil degranulation";"Trafficking and processing of endosomal TLR";"MHC class II antigen presentation";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_011181261.1	17	KEGG: 00630+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00680+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00270+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-8086;MetaCyc: PWY-6728;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-561;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-5913	"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Cysteine and methionine metabolism";"Citrate cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"Carbon fixation in photosynthetic organisms";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Partial TCA cycle (obligate autotrophs)"
XP_011181375.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_028900847.2	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_011190911.1	5	KEGG: 00270+4.2.1.109;Reactome: R-HSA-111458;Reactome: R-HSA-1237112;Reactome: R-HSA-9627069;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"Formation of apoptosome";"Methionine salvage pathway";"Regulation of the apoptosome activity";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_011188044.2	7	MetaCyc: PWY-5084;Reactome: R-HSA-71403;KEGG: 00310+2.3.1.61;Reactome: R-HSA-389661;Reactome: R-HSA-71064;KEGG: 00380+2.3.1.61;KEGG: 00020+2.3.1.61	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citric acid cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Lysine catabolism";"Tryptophan metabolism";"Citrate cycle (TCA cycle)"
XP_054084475.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_011192502.2	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_011180504.2	6	Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_011189079.2	7	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_054087652.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_011182595.1	42	Reactome: R-HSA-606279;Reactome: R-HSA-427413;Reactome: R-HSA-2299718;Reactome: R-HSA-5693607;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-5625886;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-2559586;Reactome: R-HSA-73772;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-110331;Reactome: R-HSA-5334118;Reactome: R-HSA-1221632;Reactome: R-HSA-5617472;Reactome: R-HSA-1912408;Reactome: R-HSA-427359;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-912446;Reactome: R-HSA-5578749;Reactome: R-HSA-5693565;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-9610379;Reactome: R-HSA-2559580;Reactome: R-HSA-8939236;Reactome: R-HSA-5250924;Reactome: R-HSA-9609690;Reactome: R-HSA-2559582;Reactome: R-HSA-171306;Reactome: R-HSA-9018519;Reactome: R-HSA-5693571;Reactome: R-HSA-427389;Reactome: R-HSA-73728;Reactome: R-HSA-977225;Reactome: R-HSA-3214847;Reactome: R-HSA-69473;Reactome: R-HSA-3214815;Reactome: R-HSA-110329	"Deposition of new CENPA-containing nucleosomes at the centromere";"NoRC negatively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Processing of DNA double-strand break ends";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"DNA Damage/Telomere Stress Induced Senescence";"RNA Polymerase I Promoter Escape";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged purine";"DNA methylation";"Meiotic synapsis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pre-NOTCH Transcription and Translation";"SIRT1 negatively regulates rRNA expression";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Meiotic recombination";"Transcriptional regulation by small RNAs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"HCMV Late Events";"Oxidative Stress Induced Senescence";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"B-WICH complex positively regulates rRNA expression";"HCMV Early Events";"Senescence-Associated Secretory Phenotype (SASP)";"Packaging Of Telomere Ends";"Estrogen-dependent gene expression";"Nonhomologous End-Joining (NHEJ)";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Opening";"Amyloid fiber formation";"HATs acetylate histones";"G2/M DNA damage checkpoint";"HDACs deacetylate histones";"Cleavage of the damaged pyrimidine"
XP_011176524.2	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_011192938.1	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_011176563.2	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_028900932.1	3	Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane"
XP_054083109.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_028901587.2	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_011180322.2	7	Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-6783310	"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Fanconi Anemia Pathway"
XP_011184438.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_054086444.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_011176834.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054089465.1	8	MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-6609;MetaCyc: PWY-6611;Reactome: R-HSA-5683826;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4	"Purine deoxyribonucleosides degradation II";"Purine salvage";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Surfactant metabolism";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Purine metabolism"
XP_011179601.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-166208	"Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling"
XP_011179706.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011184069.2	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_011193945.1	4	Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_028897991.1	6	MetaCyc: PWY-6123;KEGG: 00230+6.3.2.6;KEGG: 00230+4.1.1.21;MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-7234	"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III"
XP_011179222.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054085210.1	10	Reactome: R-HSA-70370;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-7328;Reactome: R-HSA-5609977;MetaCyc: PWY-6317	"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose degradation I (Leloir pathway)"
XP_011178819.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054083628.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;Reactome: R-HSA-197264;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21	"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_011183606.1	3	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism"
XP_054088095.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-164378	"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (z) signalling events";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling"
XP_054091041.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_011183701.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054086200.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_054090143.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011183975.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation"
XP_054086282.1	5	KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661	"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation"
XP_011178088.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_054091643.1	16	Reactome: R-HSA-2559585;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459	"Oncogene Induced Senescence";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_011182301.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis"
XP_011185974.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_054084234.1	6	Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_054083103.1	10	Reactome: R-HSA-182971;Reactome: R-HSA-5689880;Reactome: R-HSA-8875360;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-9636383;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-917729;Reactome: R-HSA-9635644	"EGFR downregulation";"Ub-specific processing proteases";"InlB-mediated entry of Listeria monocytogenes into host cell";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Inhibition of membrane repair"
XP_011190741.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_011189073.2	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_011183030.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation"
XP_011180486.2	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_054081915.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_011178933.2	5	MetaCyc: PWY-6317;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6	"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Galactose metabolism"
XP_011187100.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_011185819.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_011194711.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_028897200.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054087033.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_011179949.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011185754.2	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_054088000.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_054086295.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011195886.2	6	KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7290	"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_054092105.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054082593.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054084709.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_054081880.1	3	Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7	"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism"
XP_011177723.2	14	MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-6433	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_054082297.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_054081802.1	10	MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-7909;MetaCyc: PWY-3841;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-6613;MetaCyc: PWY-1722	"Folate transformations I";"Metabolism of folate and pterines";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formate assimilation into 5,10-methylenetetrahydrofolate"
XP_028900453.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_054081638.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_011189989.1	23	Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-8964315;Reactome: R-HSA-456926;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-202040;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-6814122;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-400042;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-418592	"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"G beta:gamma signalling through BTK";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"G-protein activation";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1"
XP_054088454.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054082111.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_011196708.2	8	Reactome: R-HSA-2151209;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483	"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Activation of AMPK downstream of NMDARs"
XP_054081373.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_011192624.2	5	Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
XP_011177801.1	6	MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11	"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis"
XP_011192535.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_011196883.2	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_054090428.1	9	Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-7852;MetaCyc: PWY-6147;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6703;MetaCyc: PWY-6983;MetaCyc: PWY-5663;MetaCyc: PWY-5664	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Folate biosynthesis";"Preq0 biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II"
XP_054083979.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_054084716.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_011178754.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_028894891.2	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism"
XP_011193032.2	6	Reactome: R-HSA-69166;Reactome: R-HSA-5685939;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-174437;Reactome: R-HSA-162594	"Removal of the Flap Intermediate";"HDR through MMEJ (alt-NHEJ)";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Early Phase of HIV Life Cycle"
XP_011176528.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011181587.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_054087423.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_054088207.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054091758.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_011194988.1	7	MetaCyc: PWY-7836;MetaCyc: PWY-7838;MetaCyc: PWY-7839;Reactome: R-HSA-1660662;MetaCyc: PWY-5129;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7841	"Ganglio-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis"
XP_054086198.1	3	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843	"Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_054091477.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_054086149.1	9	Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253	"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_011181072.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_028901801.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054091296.1	4	Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_011191618.2	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_011180960.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_054088867.1	11	Reactome: R-HSA-975634;Reactome: R-HSA-3560783;Reactome: R-HSA-202733;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-3000170;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801	"Retinoid metabolism and transport";"Defective B4GALT7 causes EDS, progeroid type";"Cell surface interactions at the vascular wall";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Syndecan interactions";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD"
XP_011194199.2	7	KEGG: 00680+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00051+3.1.3.11;KEGG: 00710+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00010+3.1.3.11;Reactome: R-HSA-70263	"Methane metabolism";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis"
XP_028897956.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054089357.1	3	Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_028902052.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_028895613.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011179147.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_011183958.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-8866654	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_054085405.1	11	Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-212436;Reactome: R-HSA-383280;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Generic Transcription Pathway";"Nuclear Receptor transcription pathway";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression"
XP_054083050.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_028901026.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_054088577.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011190597.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_028900154.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_011193470.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011195461.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054089721.1	4	KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"HATs acetylate histones"
XP_011191070.2	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_011186224.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7601	"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_011182565.1	6	MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11	"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis"
XP_011178416.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_054082680.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_054082838.1	3	Reactome: R-HSA-392517;Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Rap1 signalling";"Ca2+ pathway";"cGMP effects"
XP_054090805.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
XP_054091668.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_011191277.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011186346.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_028898812.2	3	MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20	"Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism"
XP_054083177.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_011182147.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054083845.1	5	MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_011181598.2	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_011187976.2	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_054088692.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011178409.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_054086776.1	4	KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450;Reactome: R-HSA-6782315;MetaCyc: PWY-2781	"Zeatin biosynthesis";"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis"
XP_011177798.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_011197013.2	6	MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15;Reactome: R-HSA-196780;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599	"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_054090168.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_011191496.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054088065.1	8	Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;MetaCyc: PWY-7221	"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis"
XP_011179333.2	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_011178398.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_011180537.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51	"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation"
XP_011196932.2	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_011189991.1	23	Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-456926;Reactome: R-HSA-8964315;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-202040;Reactome: R-HSA-418217;Reactome: R-HSA-6814122;Reactome: R-HSA-381676;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-400042;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-8964616	"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through BTK";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"G-protein activation";"G beta:gamma signalling through PLC beta";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through CDC42"
XP_011179678.2	2	Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_011176659.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213	"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs"
XP_054088186.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_011188627.1	15	Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-167243	"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery"
XP_011194331.2	58	MetaCyc: PWY-7007;Reactome: R-HSA-77310;KEGG: 00360+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-7726;MetaCyc: PWY-7656;MetaCyc: PWY-5177;MetaCyc: PWY-7606;KEGG: 00903+4.2.1.17;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7401;MetaCyc: PWY-5138;MetaCyc: PWY-5109;MetaCyc: PWY-6583;MetaCyc: PWY-5136;MetaCyc: PWY-5789;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00650+4.2.1.17;Reactome: R-HSA-77305;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00410+4.2.1.17;KEGG: 00281+4.2.1.17;MetaCyc: PWY-6945;MetaCyc: PWY-7654;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17;Reactome: R-HSA-77348;MetaCyc: PWY-6883;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;Reactome: R-HSA-77346;KEGG: 00720+4.2.1.17;MetaCyc: PWY-7779;MetaCyc: PWY-6435;MetaCyc: PWY-1361;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17;MetaCyc: PWY-7094;MetaCyc: PWY-6946;KEGG: 00362+4.2.1.17+1.1.1.35;Reactome: R-HSA-77350;Reactome: R-HSA-1482798;KEGG: 00623+1.1.1.35;KEGG: 00627+4.2.1.17;KEGG: 00930+4.2.1.17;Reactome: R-HSA-77285;MetaCyc: PWY-7216;MetaCyc: PWY-6863;KEGG: 00280+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.211;Reactome: R-HSA-77288;KEGG: 00380+4.2.1.17	"Methyl ketone biosynthesis (engineered)";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Phenylalanine metabolism";"Tryptophan metabolism";"2-methylpropene degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Spodoptera littoralis pheromone biosynthesis";"Glutaryl-coa degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Limonene and pinene degradation";"Propanoate metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Fermentation to 2-methylbutanoate";"Pyruvate fermentation to butanol I";"Fatty acid beta-oxidation II (plant peroxisome)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Caprolactam degradation";"alpha-Linolenic acid metabolism";"Butanoate metabolism";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Lysine degradation";"Fatty acid degradation";"beta-Alanine metabolism";"Geraniol degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid degradation";"Benzoate degradation";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Pyruvate fermentation to butanol II (engineered)";"Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"Androstenedione degradation";"Fatty acid elongation";"Geraniol degradation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Carbon fixation pathways in prokaryotes";"Methyl tert-butyl ether degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Benzoyl-coa degradation I (aerobic)";"Valine, leucine and isoleucine degradation";"Lysine degradation";"Fatty acid salvage";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Benzoate degradation";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Acyl chain remodeling of CL";"Toluene degradation";"Aminobenzoate degradation";"Caprolactam degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate fermentation to hexanol (engineered)";"Valine, leucine and isoleucine degradation";"Fatty acid elongation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Tryptophan metabolism"
XP_028899229.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054088821.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_011181764.2	2	Reactome: R-HSA-500753;Reactome: R-HSA-73621	"Pyrimidine biosynthesis";"Pyrimidine catabolism"
XP_011190400.2	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_011180708.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011189444.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_028895755.2	3	Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_054081607.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport"
XP_011177587.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1442490;Reactome: R-HSA-1592389	"Degradation of the extracellular matrix";"Collagen degradation";"Activation of Matrix Metalloproteinases"
XP_011188842.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011183440.2	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_028896115.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)"
XP_011188275.1	2	Reactome: R-HSA-1660661;Reactome: R-HSA-6798695	"Sphingolipid de novo biosynthesis";"Neutrophil degranulation"
XP_011186419.1	2	KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841	"Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_028898847.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011177906.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_011186215.2	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_011187305.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_011192012.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_028899268.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_011185775.1	12	MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-7230;MetaCyc: PWY-5856;MetaCyc: PWY-6708;MetaCyc: PWY-5855;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5873;MetaCyc: PWY-5857;MetaCyc: PWY-5871;MetaCyc: PWY-7233	"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)"
XP_054082524.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_011196486.2	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_054083344.1	6	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-8874081;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"Collagen degradation";"MET activates PTK2 signaling";"Collagen biosynthesis and modifying enzymes"
XP_054090522.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_054083586.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054086265.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_011186646.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054090742.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_011187547.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_011182678.2	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_054085345.1	14	Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167243	"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery"
XP_011181594.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054090304.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054083047.1	17	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9648025;Reactome: R-HSA-6804756;Reactome: R-HSA-5663220;Reactome: R-HSA-9022692;Reactome: R-HSA-2467813;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-174178;KEGG: 05170+2.7.11.1;Reactome: R-HSA-68877;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-4615885;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"EML4 and NUDC in mitotic spindle formation";"Regulation of TP53 Activity through Phosphorylation";"RHO GTPases Activate Formins";"Regulation of MECP2 expression and activity";"Separation of Sister Chromatids";"mTOR signaling pathway";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Human immunodeficiency virus 1 infection";"Mitotic Prometaphase";"Human cytomegalovirus infection";"Relaxin signaling pathway";"SUMOylation of DNA replication proteins";"PI3K-Akt signaling pathway"
XP_028895887.2	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_011179467.2	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_011194193.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054082284.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_011196459.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011177430.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_054085120.1	6	MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632	"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_028899970.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398	"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway"
XP_011194511.2	9	MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_054087494.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011187086.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054086263.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054081658.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_011190604.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-983168;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695	"Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation"
XP_011191067.2	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_011188709.2	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_011192894.2	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_054084532.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054084647.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_011189626.1	8	KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Activation of RAC1";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_011193929.2	6	MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_011186570.1	2	Reactome: R-HSA-9020702;Reactome: R-HSA-6798695	"Interleukin-1 signaling";"Neutrophil degranulation"
XP_028896605.1	5	Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation"
XP_011185076.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054087761.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054087666.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_011184940.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054082147.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_011186776.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_011176998.2	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_028896666.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_028896761.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011189936.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin"
XP_011183348.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054089164.1	6	Reactome: R-HSA-76005;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597	"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"G alpha (z) signalling events"
XP_011178773.1	12	KEGG: 00680+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142;Reactome: R-HSA-70171;KEGG: 00710+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-1861;Reactome: R-HSA-70263	"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis"
XP_011189640.1	10	MetaCyc: PWY-7909;MetaCyc: PWY-3841;MetaCyc: PWY-2201;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-5030;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497	"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Folate transformations I";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)"
XP_054088656.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"RNA polymerase II transcribes snRNA genes";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011177379.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_028900064.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_011178405.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs"
XP_011182879.1	29	MetaCyc: PWY-3162;MetaCyc: PWY-5057;KEGG: 00010+1.1.1.1;MetaCyc: PWY-6313;KEGG: 00592+1.1.1.1;KEGG: 00071+1.1.1.1;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5751;MetaCyc: PWY-5078;KEGG: 00980+1.1.1.1;MetaCyc: PWY-6587;KEGG: 00982+1.1.1.1;MetaCyc: PWY-5079;KEGG: 00350+1.1.1.1;MetaCyc: PWY-6871;MetaCyc: PWY-6333;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5486;KEGG: 00260+1.1.1.1;MetaCyc: PWY-7013;MetaCyc: PWY-6802;MetaCyc: PWY-5076;MetaCyc: PWY-5082;MetaCyc: PWY-6342;MetaCyc: PWY-7111;MetaCyc: PWY-7396;MetaCyc: PWY-7118	"L-tryptophan degradation V (side chain pathway)";"L-valine degradation II";"Glycolysis / Gluconeogenesis";"Serotonin degradation";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Retinol metabolism";"Phenylethanol biosynthesis";"L-isoleucine degradation II";"Metabolism of xenobiotics by cytochrome P450";"Pyruvate fermentation to ethanol III";"Drug metabolism - cytochrome P450";"L-phenylalanine degradation III";"Tyrosine metabolism";"3-methylbutanol biosynthesis (engineered)";"Acetaldehyde biosynthesis I";"Naphthalene degradation";"Pyruvate fermentation to ethanol I";"Chloroalkane and chloroalkene degradation";"Pyruvate fermentation to ethanol II";"Glycine, serine and threonine metabolism";"(S)-propane-1,2-diol degradation";"Salidroside biosynthesis";"L-leucine degradation III";"L-methionine degradation III";"Noradrenaline and adrenaline degradation";"Pyruvate fermentation to isobutanol (engineered)";"Butanol and isobutanol biosynthesis (engineered)";"Chitin degradation to ethanol"
XP_054091210.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-2132295;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670	"Neutrophil degranulation";"Glycosphingolipid metabolism";"MHC class II antigen presentation";"Sialic acid metabolism";"Defective NEU1 causes sialidosis"
XP_054092047.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_011178209.2	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;MetaCyc: PWY-7511	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination"
XP_054090816.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054088870.1	11	Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-3000170;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-3560783	"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"Syndecan interactions";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"Defective B4GALT7 causes EDS, progeroid type"
XP_054088063.1	8	Reactome: R-HSA-442982;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324	"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_011190890.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_054087550.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_011179221.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_028901886.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_011186149.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_054091460.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430	"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling"
XP_011194080.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_054088766.1	19	MetaCyc: PWY-6728;MetaCyc: PWY-5538;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-6969;Reactome: R-HSA-6798695;KEGG: 00020+6.2.1.5;Reactome: R-HSA-75105;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5172;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00020+2.3.3.8;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-163765	"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Neutrophil degranulation";"Citrate cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"ChREBP activates metabolic gene expression"
XP_011183553.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_011179602.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_011179005.3	9	Reactome: R-HSA-9656256;Reactome: R-HSA-110331;Reactome: R-HSA-5649702;Reactome: R-HSA-9657050;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-9656255;Reactome: R-HSA-110330;Reactome: R-HSA-110328	"Defective OGG1 Substrate Processing";"Cleavage of the damaged purine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Localization";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Binding";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_011177634.2	5	Reactome: R-HSA-3769402;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472	"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_011177835.2	3	Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5685942	"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)"
XP_054081768.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_011191629.2	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_011186517.2	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_054090809.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054086911.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011196341.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_028894474.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_054091017.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_054087651.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_011190123.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_011190164.2	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_011186415.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054088356.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_011186038.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011195430.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011187984.3	4	KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051	"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I"
XP_054091980.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_054091902.1	4	KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I"
XP_054092050.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_011191819.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_011179918.2	14	KEGG: 00670+2.1.2.1;MetaCyc: PWY-181;KEGG: 00460+2.1.2.1;MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-3661-1;MetaCyc: PWY-2161;MetaCyc: PWY-5497;KEGG: 00630+2.1.2.1;KEGG: 00680+2.1.2.1;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-3841;MetaCyc: PWY-1622	"One carbon pool by folate";"Photorespiration ";"Cyanoamino acid metabolism";"Folate transformations I";"Metabolism of folate and pterines";"Glycine betaine degradation II (mammalian)";"Folate polyglutamylation";"Purine nucleobases degradation II (anaerobic)";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Glycine, serine and threonine metabolism";"Glycine betaine degradation I";"Folate transformations II (plants)";"Formaldehyde assimilation I (serine pathway)"
XP_011183907.1	4	KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5912;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II"
XP_054087059.1	30	Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-2565942;Reactome: R-HSA-5676590;Reactome: R-HSA-5684264;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-2122947;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-400253;Reactome: R-HSA-69231;Reactome: R-HSA-2644607;Reactome: R-HSA-5607761;Reactome: R-HSA-9020702;Reactome: R-HSA-2894862;Reactome: R-HSA-1170546;Reactome: R-HSA-180534;Reactome: R-HSA-917937;Reactome: R-HSA-2644606;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783	"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PLK1 Activity at G2/M Transition";"NIK-->noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Neddylation";"CLEC7A (Dectin-1) signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Circadian Clock";"Cyclin D associated events in G1";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Prolactin receptor signaling";"Vpu mediated degradation of CD4";"Iron uptake and transport";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome"
XP_011182563.1	6	KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484	"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_054086521.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_011187181.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011186371.1	16	Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-167287;Reactome: R-HSA-8951664;Reactome: R-HSA-167246;Reactome: R-HSA-167238	"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery";"Neddylation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation"
XP_011190522.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation"
XP_054084904.1	4	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
XP_011197069.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_028899967.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430	"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling"
XP_028902221.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011178507.2	3	Reactome: R-HSA-480985;Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117	"Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins";"N-Glycan biosynthesis"
XP_054091828.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_011183702.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054086620.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_054086075.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725	"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_011194917.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-5667;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-5981	"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III"
XP_028901993.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011189326.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_011196397.2	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_054088069.1	8	Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9609736	"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors"
XP_054082077.1	3	Reactome: R-HSA-381038;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
XP_028895324.2	15	MetaCyc: PWY-5723;MetaCyc: PWY-7003;MetaCyc: PWY-7218;MetaCyc: PWY-6901;MetaCyc: PWY-5484;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6142;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383	"Rubisco shunt";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_011176655.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_011182873.1	3	Reactome: R-HSA-1369062;Reactome: R-HSA-8964058;Reactome: R-HSA-9029569	"ABC transporters in lipid homeostasis";"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_054081358.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_011186428.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054083555.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_011180087.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_011179524.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_054081142.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
XP_011186079.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_028894811.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_011184897.2	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-7214	"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_054085554.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_028894892.2	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism"
XP_011176943.2	5	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6798695	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Neutrophil degranulation"
XP_011195833.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011184509.2	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_011176500.2	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_011180740.2	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_011179380.1	3	Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane"
XP_011179302.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing"
XP_054085403.1	11	Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-9018519;Reactome: R-HSA-212436;Reactome: R-HSA-383280;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-400253	"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression";"Generic Transcription Pathway";"Nuclear Receptor transcription pathway";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock"
XP_054089851.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_028898641.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_011195965.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054081801.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_011195565.2	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
XP_011177799.1	6	KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004	"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I"
XP_054086352.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_054088537.1	4	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_054090169.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_011176801.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_011194860.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011193965.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-204174;Reactome: R-HSA-8963684	"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism"
XP_054086214.1	5	MetaCyc: PWY-7511;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-8948751	"Protein ubiquitination";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity"
XP_011178408.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids"
XP_011190390.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_011177528.1	6	MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855204;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840	"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Rho GTPase cycle"
XP_011196731.1	14	KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-7254;Reactome: R-HSA-611105;MetaCyc: PWY-6728;MetaCyc: PWY-7279;Reactome: R-HSA-71403;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-3781;MetaCyc: PWY-4302;KEGG: 00720+1.3.5.1	"Butanoate metabolism";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"Methylaspartate cycle";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)";"Oxidative phosphorylation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"Carbon fixation pathways in prokaryotes"
XP_054084951.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_011176787.2	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_028895318.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054091669.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_011194961.1	4	Reactome: R-HSA-389661;MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8;MetaCyc: PWY-7382	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_011179456.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011195242.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054082839.1	3	Reactome: R-HSA-418457;Reactome: R-HSA-4086398;Reactome: R-HSA-392517	"cGMP effects";"Ca2+ pathway";"Rap1 signalling"
XP_011177838.2	10	Reactome: R-HSA-9022692;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-9022699;Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-983231	"Regulation of MECP2 expression and activity";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates neuronal receptors and channels";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"Factors involved in megakaryocyte development and platelet production"
XP_011193283.2	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054090055.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_011179924.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895	"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis"
XP_054081183.1	29	Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-3371453;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-3108214;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-5358606;Reactome: R-HSA-68962;Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-912446;Reactome: R-HSA-6783310;Reactome: R-HSA-3371511;Reactome: R-HSA-5685938;Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-69473;Reactome: R-HSA-5655862	"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of HSF1-mediated heat shock response";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"SUMOylation of DNA damage response and repair proteins";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Activation of the pre-replicative complex";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"Meiotic recombination";"Fanconi Anemia Pathway";"HSF1 activation";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK"
XP_028901005.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948	"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_054089113.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_011194956.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation"
XP_011182285.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054088402.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_011187299.1	2	Reactome: R-HSA-190373;Reactome: R-HSA-5654726	"FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling"
XP_011190547.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_011182489.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_011189124.2	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_028902230.2	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_054081655.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054091220.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_011187495.2	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_011185559.2	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_011192649.2	5	Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
XP_054085600.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_028900692.2	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_011182673.2	3	Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_011181715.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054087522.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_011190727.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_028900611.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_054091246.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_011187626.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054082492.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054085733.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_054090840.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_054091027.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
XP_054086148.1	18	KEGG: 00710+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00250+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00270+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-7383;KEGG: 00950+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6638	"Carbon fixation in photosynthetic organisms";"Novobiocin biosynthesis";"(R)-cysteate degradation";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine biosynthesis";"Coenzyme M biosynthesis II";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism";"Sulfolactate degradation III"
XP_011189498.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_054081994.1	7	Reactome: R-HSA-6794361;Reactome: R-HSA-373753;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-212676;Reactome: R-HSA-3000170;MetaCyc: PWY-7221	"Neurexins and neuroligins";"Nephrin family interactions";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Dopamine Neurotransmitter Release Cycle";"Syndecan interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_011191823.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_054086199.1	3	KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism"
XP_011194989.1	7	MetaCyc: PWY-7836;MetaCyc: PWY-7839;MetaCyc: PWY-7838;MetaCyc: PWY-5129;Reactome: R-HSA-1660662;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7841	"Ganglio-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis"
XP_028894884.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_054091753.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_011178152.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054081497.1	10	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-200425;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-1445148	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Carnitine metabolism";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_011177834.1	6	Reactome: R-HSA-72163;MetaCyc: PWY-7511;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"mRNA Splicing - Major Pathway";"Protein ubiquitination";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_011188885.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011179037.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_011187816.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_028898135.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011186425.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_011185693.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_011182915.2	14	MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;Reactome: R-HSA-75109;KEGG: 00565+3.1.3.4	"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Synthesis of PC";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Triglyceride biosynthesis";"Ether lipid metabolism"
XP_028894311.2	10	Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702;Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-983231	"Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"Factors involved in megakaryocyte development and platelet production"
XP_054087717.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_054085739.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054088960.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054090997.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_011177162.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"Trafficking of GluR2-containing AMPA receptors";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_011189316.1	4	MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_028896717.2	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_011194927.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_054090792.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_011189115.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_054087912.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_054085395.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_011190053.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_011189169.2	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_011181724.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_011191190.2	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_011190651.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_011179880.2	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_011188892.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_011191365.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_028899741.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_011177470.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011179969.1	3	KEGG: 00790+1.1.1.153;Reactome: R-HSA-203615;Reactome: R-HSA-1474151	"Folate biosynthesis";"eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_011189536.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_011186035.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_054084622.1	16	Reactome: R-HSA-5673001;Reactome: R-HSA-6785631;Reactome: R-HSA-1963642;Reactome: R-HSA-6811558;Reactome: R-HSA-8863795;Reactome: R-HSA-1250196;Reactome: R-HSA-8847993;Reactome: R-HSA-1250347;Reactome: R-HSA-1227986;Reactome: R-HSA-1963640;Reactome: R-HSA-1251985;Reactome: R-HSA-9664565;Reactome: R-HSA-1250342;Reactome: R-HSA-1236394;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604	"RAF/MAP kinase cascade";"ERBB2 Regulates Cell Motility";"PI3K events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"SHC1 events in ERBB4 signaling";"Signaling by ERBB2";"GRB2 events in ERBB2 signaling";"Nuclear signaling by ERBB4";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB4 signaling";"Signaling by ERBB4";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling"
XP_011186418.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011185644.2	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-4085001;Reactome: R-HSA-2132295	"Neutrophil degranulation";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"Sialic acid metabolism";"MHC class II antigen presentation"
XP_054088617.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_011196957.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_028895172.2	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_028895534.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_011190666.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_011184903.2	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_011190761.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_054091624.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011182373.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054090785.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_011178845.2	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_054091825.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_054086078.1	13	MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-5538;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969	"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_011180013.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_011195467.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054086429.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_054091061.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054081355.1	6	Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427359	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression"
XP_011189826.2	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_054081156.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054082122.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5080	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I"
XP_054090163.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_028896805.2	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_028894006.2	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_054086331.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_054090059.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_054089562.1	6	Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-416476	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events"
XP_011187007.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_011189804.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_028900790.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_011183643.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054087372.1	9	KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_011189605.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054091132.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_054086100.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_011184905.2	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_011191786.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_011183882.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054081769.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_011184771.2	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_011191628.2	30	Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-2564830;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_011195515.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_011191580.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_011180438.2	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_054091823.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_011187947.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011182375.2	9	KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;Reactome: R-HSA-156590;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00983+2.5.1.18	"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Glutathione conjugation";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Drug metabolism - other enzymes"
XP_054091665.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_011184453.1	22	MetaCyc: PWY-6142;MetaCyc: PWY-8013;KEGG: 00010+5.3.1.9;KEGG: 00500+5.3.1.9;Reactome: R-HSA-6798695;MetaCyc: PWY-7238;MetaCyc: PWY-6981;MetaCyc: PWY-5384;MetaCyc: PWY-5514;MetaCyc: PWY-7347;KEGG: 00520+5.3.1.9;MetaCyc: PWY-5659;Reactome: R-HSA-70263;MetaCyc: PWY-622;MetaCyc: PWY-5054;MetaCyc: PWY-6992;MetaCyc: PWY-3801;MetaCyc: PWY-7385;MetaCyc: PWY-621;KEGG: 00030+5.3.1.9;Reactome: R-HSA-5628897;Reactome: R-HSA-70171	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Neutrophil degranulation";"Sucrose biosynthesis II";"Chitin biosynthesis";"Sucrose degradation IV (sucrose phosphorylase)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Sucrose biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Gluconeogenesis";"Starch biosynthesis";"D-sorbitol biosynthesis I";"1,5-anhydrofructose degradation";"Sucrose degradation II (sucrose synthase)";"1,3-propanediol biosynthesis (engineered)";"Sucrose degradation III (sucrose invertase)";"Pentose phosphate pathway";"TP53 Regulates Metabolic Genes";"Glycolysis"
XP_011193514.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513	"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_011190001.2	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_054083986.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_028895819.2	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_011182913.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054082461.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_011188370.2	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_011181127.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054086396.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_011180361.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_011190055.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_011190309.2	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_054085393.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_011184850.2	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_011177964.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_011180479.2	8	Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68827	"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex"
XP_028900063.2	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_011177700.1	3	Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_011192451.1	17	Reactome: R-HSA-5663220;Reactome: R-HSA-6804756;Reactome: R-HSA-9648025;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-4615885;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-68877;KEGG: 05170+2.7.11.1;Reactome: R-HSA-174178;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2467813;Reactome: R-HSA-9022692	"RHO GTPases Activate Formins";"Regulation of TP53 Activity through Phosphorylation";"EML4 and NUDC in mitotic spindle formation";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"SUMOylation of DNA replication proteins";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Mitotic Prometaphase";"Human immunodeficiency virus 1 infection";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"mTOR signaling pathway";"Separation of Sister Chromatids";"Regulation of MECP2 expression and activity"
XP_011184812.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011182289.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011190039.3	16	Reactome: R-HSA-70171;KEGG: 00680+4.2.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-6886;MetaCyc: PWY-8004;KEGG: 00010+4.2.1.11;Reactome: R-HSA-70263;MetaCyc: PWY-7003;MetaCyc: PWY-5723;MetaCyc: PWY-7218;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-1622;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-7124	"Glycolysis";"Methane metabolism";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Glycerol degradation to butanol";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ethylene biosynthesis V (engineered)"
XP_011197064.2	1	Reactome: R-HSA-5676934	"Protein repair"
XP_011181582.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054088107.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_011181943.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054081659.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054088688.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_028901994.2	5	Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-936964	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_054089001.1	7	KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;MetaCyc: PWY-5921;Reactome: R-HSA-5628897	"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes"
XP_011189366.2	2	KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_054086268.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011184737.1	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
XP_054081653.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_011189086.2	14	Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700	"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_011185160.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011180434.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011182283.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054090666.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_028896340.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_011190498.2	4	KEGG: 00900+2.5.1.87;MetaCyc: PWY-6129;Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Terpenoid backbone biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_054089536.1	5	Reactome: R-HSA-9033500;Reactome: R-HSA-75896;MetaCyc: PWY-7782;Reactome: R-HSA-9033241;KEGG: 00565+2.5.1.26	"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"Peroxisomal protein import";"Ether lipid metabolism"
XP_054084836.1	11	KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-9614657;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-163680;Reactome: R-HSA-6804756	"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"FOXO-mediated transcription of cell death genes";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation"
XP_011196139.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_054091085.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_011177052.1	5	Reactome: R-HSA-5658442;Reactome: R-HSA-5218921;Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-186763	"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"Downstream signal transduction"
XP_011184508.2	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_054089941.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_011196691.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_054085735.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_011178887.3	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011196612.2	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418594	"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (i) signalling events"
XP_011181858.2	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_054087672.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_011196093.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_054089128.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_011184932.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_054086970.1	7	Reactome: R-HSA-381033;Reactome: R-HSA-983170;Reactome: R-HSA-3371453;Reactome: R-HSA-381042;Reactome: R-HSA-381070;Reactome: R-HSA-114608;Reactome: R-HSA-381183	"ATF6 (ATF6-alpha) activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of HSF1-mediated heat shock response";"PERK regulates gene expression";"IRE1alpha activates chaperones";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_011187770.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011193963.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011191056.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054090512.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_054088068.1	8	Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9609736	"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors"
XP_011186592.2	4	KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32	"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism"
XP_028894356.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_054091829.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_054087816.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_011192146.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011187890.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_054084397.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_011190609.2	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_011193285.2	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_011196566.2	5	Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-69205;Reactome: R-HSA-68962	"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"G1/S-Specific Transcription";"Activation of the pre-replicative complex"
XP_011191116.2	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_054083466.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011179919.2	14	MetaCyc: PWY-3661-1;Reactome: R-HSA-196757;MetaCyc: PWY-2201;KEGG: 00460+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-3841;MetaCyc: PWY-1622;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3661;KEGG: 00630+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-2161	"Glycine betaine degradation II (mammalian)";"Metabolism of folate and pterines";"Folate transformations I";"Cyanoamino acid metabolism";"One carbon pool by folate";"Photorespiration ";"Folate transformations II (plants)";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Glycine betaine degradation I";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Purine nucleobases degradation II (anaerobic)";"Folate polyglutamylation"
XP_011176545.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054090756.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054084094.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_011178739.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011176944.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054081185.1	29	Reactome: R-HSA-3371511;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-912446;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-3371453;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-69166;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5651801;Reactome: R-HSA-68962;Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-110320;Reactome: R-HSA-5358606;Reactome: R-HSA-176187	"HSF1 activation";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Meiotic recombination";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Removal of the Flap Intermediate";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of the pre-replicative complex";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"Translesion Synthesis by POLH";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Activation of ATR in response to replication stress"
XP_054090053.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_054081386.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011185196.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054088720.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis"
XP_011195032.1	33	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-4570464;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-159227	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"SUMOylation of RNA binding proteins";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"snRNP Assembly";"tRNA processing in the nucleus";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA"
XP_054084478.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_054088286.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011195241.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054087419.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_054082853.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_011181378.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_011193008.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_054083579.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054088540.1	4	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-499943;Reactome: R-HSA-2161541	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism"
XP_028893555.2	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_011180133.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_011192935.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_011184856.1	7	MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-7282;KEGG: 00230+2.4.2.14	"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine metabolism"
XP_011181674.2	6	MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_011196842.2	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_054088903.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_011184889.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011177719.2	14	MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602	"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_011189750.1	27	Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531	"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus"
XP_011182291.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011196101.2	3	MetaCyc: PWY-7999;Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90	"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_011188932.2	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_011193188.2	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054091894.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_054087406.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054092067.1	5	MetaCyc: PWY-7817;Reactome: R-HSA-1483148;MetaCyc: PWY-5269;MetaCyc: PWY-5668;KEGG: 00564+2.7.8.5	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PG";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism"
XP_054090396.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-76005	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+"
XP_054088526.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_054088259.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_028899851.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_028898479.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_011188376.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_011193948.1	4	Reactome: R-HSA-2161541;Reactome: R-HSA-499943;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_011190423.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_054084952.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_054088043.1	12	Reactome: R-HSA-451308;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-438066	"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Long-term potentiation";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_011193236.2	11	Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167246	"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript"
XP_011195807.2	3	MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)"
XP_054084684.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011187206.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011176915.1	19	Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-4420097;Reactome: R-HSA-5626467;Reactome: R-HSA-2029482;Reactome: R-HSA-182971;Reactome: R-HSA-194840;Reactome: R-HSA-5687128;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-8964616;Reactome: R-HSA-114604;Reactome: R-HSA-983231;Reactome: R-HSA-8950505;Reactome: R-HSA-5627123;Reactome: R-HSA-5625970;Reactome: R-HSA-418885;Reactome: R-HSA-428543;Reactome: R-HSA-389359	"Myogenesis";"RHO GTPases Activate Formins";"VEGFA-VEGFR2 Pathway";"RHO GTPases activate IQGAPs";"Regulation of actin dynamics for phagocytic cup formation";"EGFR downregulation";"Rho GTPase cycle";"MAPK6/MAPK4 signaling";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"G beta:gamma signalling through CDC42";"GPVI-mediated activation cascade";"Factors involved in megakaryocyte development and platelet production";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate PAKs";"RHO GTPases activate KTN1";"DCC mediated attractive signaling";"Inactivation of CDC42 and RAC1";"CD28 dependent Vav1 pathway"
XP_054089144.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400	"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER"
XP_054087620.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_028899770.2	8	Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5689880;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_054089585.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_054082491.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054089677.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_011194118.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;MetaCyc: PWY-7511;Reactome: R-HSA-2644606	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_011186001.2	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_011178574.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011187637.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011190148.1	9	Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_054085246.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_011189871.1	18	Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-561;KEGG: 00720+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-7115;MetaCyc: PWY-1622;KEGG: 00270+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00680+1.1.1.37	"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Carbon fixation in photosynthetic organisms";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Formaldehyde assimilation I (serine pathway)";"Cysteine and methionine metabolism";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methane metabolism"
XP_011191907.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011181488.2	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_054084667.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011182072.2	6	Reactome: R-HSA-6796648;Reactome: R-HSA-5632927;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565	"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_011192252.2	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_054086632.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_054082725.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_054091600.1	5	Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-5221030;Reactome: R-HSA-110357	"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1"
XP_054086808.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054088401.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_028896075.2	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_054087521.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_054083126.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_011187265.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_011192210.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011191047.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_054089225.1	83	Reactome: R-HSA-2730905;Reactome: R-HSA-983695;Reactome: R-HSA-8856825;Reactome: R-HSA-2029482;Reactome: R-HSA-2428933;Reactome: R-HSA-8856828;Reactome: R-HSA-388841;Reactome: R-HSA-74749;Reactome: R-HSA-2871796;Reactome: R-HSA-1257604;Reactome: R-HSA-5654732;Reactome: R-HSA-2871809;Reactome: R-HSA-1250196;Reactome: R-HSA-1433557;Reactome: R-HSA-8851907;Reactome: R-HSA-8853659;Reactome: R-HSA-167044;Reactome: R-HSA-1236382;Reactome: R-HSA-5654700;Reactome: R-HSA-186763;Reactome: R-HSA-6807004;Reactome: R-HSA-8851805;Reactome: R-HSA-5654689;Reactome: R-HSA-5654727;Reactome: R-HSA-6811558;Reactome: R-HSA-5655302;Reactome: R-HSA-182971;Reactome: R-HSA-180336;Reactome: R-HSA-5654726;Reactome: R-HSA-1963642;Reactome: R-HSA-9664565;Reactome: R-HSA-5654712;Reactome: R-HSA-8875656;Reactome: R-HSA-2219530;Reactome: R-HSA-5637810;Reactome: R-HSA-179812;Reactome: R-HSA-354194;Reactome: R-HSA-9634285;Reactome: R-HSA-8875360;Reactome: R-HSA-8853338;Reactome: R-HSA-2424491;Reactome: R-HSA-74751;Reactome: R-HSA-5654688;Reactome: R-HSA-5654695;Reactome: R-HSA-9028731;Reactome: R-HSA-912526;Reactome: R-HSA-5654693;Reactome: R-HSA-8983432;Reactome: R-HSA-1839117;Reactome: R-HSA-2179392;Reactome: R-HSA-5654699;Reactome: R-HSA-9028335;Reactome: R-HSA-5654720;Reactome: R-HSA-1433559;Reactome: R-HSA-5654719;Reactome: R-HSA-391160;Reactome: R-HSA-8865999;Reactome: R-HSA-5654706;Reactome: R-HSA-912631;Reactome: R-HSA-1250347;Reactome: R-HSA-8853334;Reactome: R-HSA-9607240;Reactome: R-HSA-109704;Reactome: R-HSA-389359;Reactome: R-HSA-5655253;Reactome: R-HSA-5654704;Reactome: R-HSA-512988;Reactome: R-HSA-5673001;Reactome: R-HSA-9645135;Reactome: R-HSA-5654710;Reactome: R-HSA-5663213;Reactome: R-HSA-1963640;Reactome: R-HSA-9034864;Reactome: R-HSA-8875555;Reactome: R-HSA-5655291;Reactome: R-HSA-180292;Reactome: R-HSA-9027284;Reactome: R-HSA-375165;Reactome: R-HSA-210993;Reactome: R-HSA-9026519;Reactome: R-HSA-5654733;Reactome: R-HSA-1295596;Reactome: R-HSA-112412	"Role of LAT2/NTAL/LAB on calcium mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"SHC-related events triggered by IGF1R";"Clathrin-mediated endocytosis";"Costimulation by the CD28 family";"Signal attenuation";"FCERI mediated MAPK activation";"PIP3 activates AKT signaling";"Negative regulation of FGFR3 signaling";"FCERI mediated Ca+2 mobilization";"SHC1 events in ERBB2 signaling";"Signaling by SCF-KIT";"MET activates PI3K/AKT signaling";"RET signaling";"Signalling to RAS";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"FRS-mediated FGFR2 signaling";"Downstream signal transduction";"Negative regulation of MET activity";"MET activates RAS signaling";"PI-3K cascade:FGFR1";"Negative regulation of FGFR2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by FGFR1 in disease";"EGFR downregulation";"SHC1 events in EGFR signaling";"Negative regulation of FGFR1 signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"FRS-mediated FGFR4 signaling";"MET receptor recycling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Constitutive Signaling by EGFRvIII";"GRB2 events in EGFR signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Constitutive Signaling by Overexpressed ERBB2";"InlB-mediated entry of Listeria monocytogenes into host cell";"Signaling by FGFR3 point mutants in cancer";"DAP12 signaling";"Insulin receptor signalling cascade";"SHC-mediated cascade:FGFR1";"PI-3K cascade:FGFR2";"Activated NTRK2 signals through FRS2 and FRS3";"Interleukin receptor SHC signaling";"FRS-mediated FGFR1 signaling";"Interleukin-15 signaling";"Signaling by cytosolic FGFR1 fusion mutants";"EGFR Transactivation by Gastrin";"SHC-mediated cascade:FGFR2";"Activated NTRK2 signals through PI3K";"PI-3K cascade:FGFR4";"Regulation of KIT signaling";"SHC-mediated cascade:FGFR4";"Signal regulatory protein family interactions";"MET activates PTPN11";"FRS-mediated FGFR3 signaling";"Regulation of signaling by CBL";"SHC1 events in ERBB4 signaling";"Signaling by FGFR3 fusions in cancer";"FLT3 Signaling";"PI3K Cascade";"CD28 dependent Vav1 pathway";"Signaling by FGFR2 in disease";"SHC-mediated cascade:FGFR3";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RAF/MAP kinase cascade";"STAT5 Activation";"PI-3K cascade:FGFR3";"RHO GTPases Activate WASPs and WAVEs";"GRB2 events in ERBB2 signaling";"Activated NTRK3 signals through RAS";"MET activates RAP1 and RAC1";"Signaling by FGFR4 in disease";"GAB1 signalosome";"Erythropoietin activates RAS";"NCAM signaling for neurite out-growth";"Tie2 Signaling";"Activated NTRK2 signals through RAS";"Negative regulation of FGFR4 signaling";"Spry regulation of FGF signaling";"SOS-mediated signalling"
XP_028897922.2	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_011184342.2	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_028895698.2	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_011192325.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_011178092.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054087911.1	10	Reactome: R-HSA-3214847;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042	"HATs acetylate histones";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_054092108.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054090791.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_011177276.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011195763.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-196108	"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis"
XP_011191152.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513	"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_011176835.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_011187956.2	6	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes"
XP_028895251.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011195066.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_011182436.1	5	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.10;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_011180178.1	3	Reactome: R-HSA-111471;Reactome: R-HSA-140837;Reactome: R-HSA-9645722	"Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"
XP_011176745.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation"
XP_011178151.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_011192902.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_011196063.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_054084433.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011185829.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054082948.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_054090970.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_011178365.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011178271.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_011185578.2	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_054088098.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1	"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"G alpha (s) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Purine metabolism"
XP_054084740.1	15	Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-2173796;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-176034	"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins"
XP_011183387.1	56	Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-187577	"Ub-specific processing proteases";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21"
XP_054082886.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054087584.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_054086332.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_054084520.1	3	Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5685942	"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)"
XP_054082121.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7035	"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis"
XP_028894133.1	4	Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762	"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_028894908.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_011180612.2	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_054087145.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054085663.1	4	Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I"
XP_011184883.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA"
XP_028901795.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011187073.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_011197098.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054091062.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054084621.1	16	Reactome: R-HSA-8863795;Reactome: R-HSA-6811558;Reactome: R-HSA-1963642;Reactome: R-HSA-5673001;Reactome: R-HSA-6785631;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-1250342;Reactome: R-HSA-1236394;Reactome: R-HSA-1251985;Reactome: R-HSA-1963640;Reactome: R-HSA-9664565;Reactome: R-HSA-1250347;Reactome: R-HSA-1227986;Reactome: R-HSA-1250196;Reactome: R-HSA-8847993	"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling";"RAF/MAP kinase cascade";"ERBB2 Regulates Cell Motility";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI3K events in ERBB4 signaling";"Signaling by ERBB4";"Nuclear signaling by ERBB4";"GRB2 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB4 signaling";"Signaling by ERBB2";"SHC1 events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling"
XP_054081793.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011184708.1	3	KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158;MetaCyc: PWY-8099	"Folate biosynthesis";"L-phenylalanine degradation V";"Tetrahydropteridine recycling"
XP_054091457.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364	"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_028898751.2	14	Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593	"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity"
XP_011181052.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_011182900.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_028899742.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054083573.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011190762.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6811438	"RAB geranylgeranylation";"Intra-Golgi traffic"
XP_054089988.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_011188850.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_011178105.2	4	KEGG: 00510+2.4.1.260;Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_028893648.1	22	Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-141444;Reactome: R-HSA-432142;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716	"RAF activation";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Platelet sensitization by LDL";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin"
XP_011190264.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_011184321.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_011191501.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_028901918.2	11	Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-5610787	"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (s) signalling events";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state"
XP_054090530.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_011187620.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_011189762.2	5	Reactome: R-HSA-879415;Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-532668;Reactome: R-HSA-8957275	"Advanced glycosylation endproduct receptor signaling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation"
XP_054085665.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_011188397.2	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_011194851.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-1221632;Reactome: R-HSA-3108214;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519	"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression"
XP_011190527.2	5	Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310	"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway"
XP_054091131.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_011193358.2	5	Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310	"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Fanconi Anemia Pathway"
XP_054083575.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_054087371.1	18	Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7417;Reactome: R-HSA-1483166	"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA"
XP_028899962.2	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_054083933.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011178759.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054089561.1	6	Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-416476	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events"
XP_028902188.1	10	MetaCyc: PWY-6362;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6369;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6372;MetaCyc: PWY-6361;Reactome: R-HSA-1855191	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of IPs in the nucleus"
XP_011189331.2	6	KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23	"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Other glycan degradation";"Galactose metabolism"
XP_028894777.2	10	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-2151209;Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-1445148	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_011187646.1	30	Reactome: R-HSA-5607764;Reactome: R-HSA-2122947;Reactome: R-HSA-983168;Reactome: R-HSA-2565942;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-2644607;Reactome: R-HSA-5607761;Reactome: R-HSA-9020702;Reactome: R-HSA-2894862;Reactome: R-HSA-1170546;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-917937;Reactome: R-HSA-5610785;Reactome: R-HSA-2644606;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-400253;Reactome: R-HSA-69231	"CLEC7A (Dectin-1) signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PLK1 Activity at G2/M Transition";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Prolactin receptor signaling";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"Iron uptake and transport";"GLI3 is processed to GLI3R by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Circadian Clock";"Cyclin D associated events in G1"
XP_054086826.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011194129.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_028899784.2	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_011193900.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011188903.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054082598.1	5	Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-164843	"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"2-LTR circle formation"
XP_011180926.1	13	Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-437239;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-182218;Reactome: R-HSA-5140745;Reactome: R-HSA-8964038;Reactome: R-HSA-8866427	"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"Recycling pathway of L1";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"LDL clearance";"VLDLR internalisation and degradation"
XP_011180362.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_011188138.1	5	KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I"
XP_054081987.1	8	KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Activation of RAC1";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_028900458.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_011193764.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_054081633.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_011192452.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_011184811.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054089917.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054082729.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_054081506.1	12	MetaCyc: PWY-6936;MetaCyc: PWY-2821;MetaCyc: PWY-801;MetaCyc: PWY-6309;KEGG: 00380+2.6.1.7;Reactome: R-HSA-71240;KEGG: 00450+4.4.1.13;MetaCyc: PWY-601;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-7901;MetaCyc: PWY-1187	"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine";"Homocysteine and cysteine interconversion";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Tryptophan catabolism";"Selenocompound metabolism";"Glucosinolate biosynthesis from tryptophan";"Cysteine and methionine metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from homomethionine"
XP_011177686.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_011188259.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_011188526.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_011196888.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011190195.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054090464.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054090423.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_054081964.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_054090214.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011176523.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_054089750.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_054087428.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_011186294.2	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_054084435.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011191440.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181430	"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle"
XP_011193212.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-166208	"Neutrophil degranulation";"Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"mTOR signalling";"mTORC1-mediated signalling"
XP_054086163.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054086124.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_054089942.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_028896337.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_011193354.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_011191204.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"PLC beta mediated events";"G alpha (i) signalling events"
XP_054090429.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_054088990.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_028896961.1	3	KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048	"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG"
XP_054083978.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_011184740.1	4	MetaCyc: PWY-4361;Reactome: R-HSA-1237112;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism"
XP_011178934.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054090967.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_011183824.1	5	KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661	"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation"
XP_054087671.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_028896570.2	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_011186976.2	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_011189988.1	23	Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-456926;Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-500657;Reactome: R-HSA-418597;Reactome: R-HSA-6814122;Reactome: R-HSA-381676;Reactome: R-HSA-202040;Reactome: R-HSA-418217;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-420092	"G alpha (12/13) signalling events";"G alpha (s) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors";"G alpha (z) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G-protein activation";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-type ligand receptors"
XP_011196709.2	8	Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209	"Lipophagy";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
XP_054085166.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_054083452.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_011184384.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_054089080.1	5	Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_054089414.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054081639.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_011196510.2	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_054089223.1	83	Reactome: R-HSA-388841;Reactome: R-HSA-8856828;Reactome: R-HSA-74749;Reactome: R-HSA-2871796;Reactome: R-HSA-1257604;Reactome: R-HSA-5654732;Reactome: R-HSA-8851907;Reactome: R-HSA-1250196;Reactome: R-HSA-2871809;Reactome: R-HSA-1433557;Reactome: R-HSA-167044;Reactome: R-HSA-8853659;Reactome: R-HSA-2730905;Reactome: R-HSA-983695;Reactome: R-HSA-8856825;Reactome: R-HSA-2029482;Reactome: R-HSA-2428933;Reactome: R-HSA-8875656;Reactome: R-HSA-5654712;Reactome: R-HSA-9664565;Reactome: R-HSA-5637810;Reactome: R-HSA-2219530;Reactome: R-HSA-9634285;Reactome: R-HSA-8875360;Reactome: R-HSA-179812;Reactome: R-HSA-354194;Reactome: R-HSA-8853338;Reactome: R-HSA-74751;Reactome: R-HSA-2424491;Reactome: R-HSA-5654688;Reactome: R-HSA-5654700;Reactome: R-HSA-186763;Reactome: R-HSA-1236382;Reactome: R-HSA-6811558;Reactome: R-HSA-5655302;Reactome: R-HSA-5654727;Reactome: R-HSA-6807004;Reactome: R-HSA-8851805;Reactome: R-HSA-5654689;Reactome: R-HSA-180336;Reactome: R-HSA-5654726;Reactome: R-HSA-182971;Reactome: R-HSA-1963642;Reactome: R-HSA-5654720;Reactome: R-HSA-9028335;Reactome: R-HSA-391160;Reactome: R-HSA-8865999;Reactome: R-HSA-1433559;Reactome: R-HSA-5654719;Reactome: R-HSA-5654706;Reactome: R-HSA-109704;Reactome: R-HSA-9607240;Reactome: R-HSA-389359;Reactome: R-HSA-1250347;Reactome: R-HSA-912631;Reactome: R-HSA-8853334;Reactome: R-HSA-912526;Reactome: R-HSA-5654693;Reactome: R-HSA-5654695;Reactome: R-HSA-9028731;Reactome: R-HSA-8983432;Reactome: R-HSA-2179392;Reactome: R-HSA-1839117;Reactome: R-HSA-5654699;Reactome: R-HSA-8875555;Reactome: R-HSA-1963640;Reactome: R-HSA-9034864;Reactome: R-HSA-5655291;Reactome: R-HSA-375165;Reactome: R-HSA-210993;Reactome: R-HSA-9026519;Reactome: R-HSA-180292;Reactome: R-HSA-9027284;Reactome: R-HSA-112412;Reactome: R-HSA-1295596;Reactome: R-HSA-5654733;Reactome: R-HSA-5655253;Reactome: R-HSA-512988;Reactome: R-HSA-5654704;Reactome: R-HSA-5673001;Reactome: R-HSA-5663213;Reactome: R-HSA-9645135;Reactome: R-HSA-5654710	"Costimulation by the CD28 family";"Clathrin-mediated endocytosis";"Signal attenuation";"FCERI mediated MAPK activation";"PIP3 activates AKT signaling";"Negative regulation of FGFR3 signaling";"MET activates PI3K/AKT signaling";"SHC1 events in ERBB2 signaling";"FCERI mediated Ca+2 mobilization";"Signaling by SCF-KIT";"Signalling to RAS";"RET signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"SHC-related events triggered by IGF1R";"MET receptor recycling";"FRS-mediated FGFR4 signaling";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Aberrant PI3K in Cancer";"Constitutive Signaling by Overexpressed ERBB2";"InlB-mediated entry of Listeria monocytogenes into host cell";"GRB2 events in EGFR signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Signaling by FGFR3 point mutants in cancer";"Insulin receptor signalling cascade";"DAP12 signaling";"SHC-mediated cascade:FGFR1";"FRS-mediated FGFR2 signaling";"Downstream signal transduction";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by FGFR1 in disease";"Negative regulation of FGFR2 signaling";"Negative regulation of MET activity";"MET activates RAS signaling";"PI-3K cascade:FGFR1";"SHC1 events in EGFR signaling";"Negative regulation of FGFR1 signaling";"EGFR downregulation";"PI3K events in ERBB2 signaling";"PI-3K cascade:FGFR4";"Activated NTRK2 signals through PI3K";"Signal regulatory protein family interactions";"MET activates PTPN11";"Regulation of KIT signaling";"SHC-mediated cascade:FGFR4";"FRS-mediated FGFR3 signaling";"PI3K Cascade";"FLT3 Signaling";"CD28 dependent Vav1 pathway";"SHC1 events in ERBB4 signaling";"Regulation of signaling by CBL";"Signaling by FGFR3 fusions in cancer";"Interleukin receptor SHC signaling";"FRS-mediated FGFR1 signaling";"PI-3K cascade:FGFR2";"Activated NTRK2 signals through FRS2 and FRS3";"Interleukin-15 signaling";"EGFR Transactivation by Gastrin";"Signaling by cytosolic FGFR1 fusion mutants";"SHC-mediated cascade:FGFR2";"MET activates RAP1 and RAC1";"GRB2 events in ERBB2 signaling";"Activated NTRK3 signals through RAS";"Signaling by FGFR4 in disease";"NCAM signaling for neurite out-growth";"Tie2 Signaling";"Activated NTRK2 signals through RAS";"GAB1 signalosome";"Erythropoietin activates RAS";"SOS-mediated signalling";"Spry regulation of FGF signaling";"Negative regulation of FGFR4 signaling";"Signaling by FGFR2 in disease";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"SHC-mediated cascade:FGFR3";"RAF/MAP kinase cascade";"RHO GTPases Activate WASPs and WAVEs";"STAT5 Activation";"PI-3K cascade:FGFR3"
XP_011182008.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_011196153.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054090984.1	15	Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944	"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2"
XP_028899299.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_011190871.2	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_011184202.1	3	Reactome: R-HSA-1810476;Reactome: R-HSA-933542;Reactome: R-HSA-445989	"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_011185089.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_028901838.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_011194123.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011183314.2	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_028899114.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_011196577.1	13	Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-9646399;Reactome: R-HSA-5689877;Reactome: R-HSA-5689896;Reactome: R-HSA-110320;Reactome: R-HSA-8866654;Reactome: R-HSA-532668;Reactome: R-HSA-8876725;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-3371511	"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Aggrephagy";"Josephin domain DUBs";"Ovarian tumor domain proteases";"Translesion Synthesis by POLH";"E3 ubiquitin ligases ubiquitinate target proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein methylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation";"ABC-family proteins mediated transport";"HSF1 activation"
XP_011186690.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011192687.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_011180336.1	3	Reactome: R-HSA-71262;KEGG: 00310+1.14.11.8;MetaCyc: PWY-6100	"Carnitine synthesis";"Lysine degradation";"L-carnitine biosynthesis"
XP_054088905.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_011192575.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_011192933.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_028895953.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011191849.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054088771.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_011197045.1	19	MetaCyc: PWY-7383;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5913;Reactome: R-HSA-70263;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-561;KEGG: 00720+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-8086;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-1622;KEGG: 00270+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00680+1.1.1.37	"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"Gluconeogenesis";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Carbon fixation in photosynthetic organisms";"Citrate cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Cysteine and methionine metabolism";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methane metabolism"
XP_054087198.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054090511.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_028899482.2	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054088045.1	12	Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308;Reactome: R-HSA-8849932	"Long-term potentiation";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules"
XP_011190556.2	4	Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;KEGG: 00670+1.5.1.6	"Metabolism of folate and pterines";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate"
XP_011177763.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_054088124.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_011176973.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_011180770.2	14	MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7601	"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_011195451.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011193177.1	8	Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-4608870;Reactome: R-HSA-373080;Reactome: R-HSA-4641263;Reactome: R-HSA-4086398;Reactome: R-HSA-5340588	"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"Asymmetric localization of PCP proteins";"Class B/2 (Secretin family receptors)";"Regulation of FZD by ubiquitination";"Ca2+ pathway";"RNF mutants show enhanced WNT signaling and proliferation"
XP_011193272.2	6	Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Neutrophil degranulation";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_011196776.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_011181323.2	16	Reactome: R-HSA-8847993;Reactome: R-HSA-1250196;Reactome: R-HSA-1227986;Reactome: R-HSA-1250347;Reactome: R-HSA-9664565;Reactome: R-HSA-1251985;Reactome: R-HSA-1963640;Reactome: R-HSA-1236394;Reactome: R-HSA-1250342;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-6785631;Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558	"ERBB2 Activates PTK6 Signaling";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2";"SHC1 events in ERBB4 signaling";"Signaling by ERBB2 KD Mutants";"Nuclear signaling by ERBB4";"GRB2 events in ERBB2 signaling";"Signaling by ERBB4";"PI3K events in ERBB4 signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"ERBB2 Regulates Cell Motility";"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_011197124.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_011194180.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_011191853.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_011182555.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_011196073.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937072	"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_011186253.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_011177343.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011194362.2	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_054085292.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_028900608.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_054086850.1	13	KEGG: 04926+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-3928663;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-4420097;Reactome: R-HSA-5627117;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"EPHB-mediated forward signaling";"PI3K-Akt signaling pathway";"Sema4D induced cell migration and growth-cone collapse";"EPHA-mediated growth cone collapse";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate ROCKs";"Thermogenesis";"Human papillomavirus infection"
XP_054091658.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_054086812.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_011185529.1	2	KEGG: 00513+2.4.1.142;KEGG: 00510+2.4.1.142	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_054091117.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_011190811.1	34	Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-141444;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-9639288;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-5663220;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-9648025	"Transcriptional regulation by small RNAs";"snRNP Assembly";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Amino acids regulate mTORC1";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"RHO GTPases Activate Formins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation"
XP_011182733.2	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_011179555.1	10	KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23	"Other glycan degradation";"Galactose metabolism";"HS-GAG degradation";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series"
XP_011191491.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_011187560.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_011184583.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_011188053.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_011185176.1	11	Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-2173796;Reactome: R-HSA-72163	"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"mRNA Splicing - Major Pathway"
XP_054086905.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_011177698.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054088857.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054083267.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_054089087.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_028898198.2	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_054087577.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-5667;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51	"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism"
XP_054089280.1	7	KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;Reactome: R-HSA-2029485;MetaCyc: PWY-3561;KEGG: 00564+3.1.4.4	"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG";"Synthesis of PA";"Role of phospholipids in phagocytosis";"Choline biosynthesis III";"Glycerophospholipid metabolism"
XP_054088997.1	7	Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921;Reactome: R-HSA-5628897	"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes"
XP_011178261.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_011177097.2	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_011192879.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_054085285.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-432040	"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (s) signalling events";"G alpha (z) signalling events";"Purine metabolism";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_011183077.1	5	Reactome: R-HSA-2206305;Reactome: R-HSA-6798695;Reactome: R-HSA-432720;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14	"MPS IIID - Sanfilippo syndrome D";"Neutrophil degranulation";"Lysosome Vesicle Biogenesis";"Keratan sulfate degradation";"Glycosaminoglycan degradation"
XP_011176471.2	22	Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262	"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_011196149.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_011190439.2	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_054081460.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_011184414.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_054082780.1	5	Reactome: R-HSA-9013973;Reactome: R-HSA-918233;Reactome: R-HSA-933541;Reactome: R-HSA-936964;Reactome: R-HSA-936440	"TICAM1-dependent activation of IRF3/IRF7";"TRAF3-dependent IRF activation pathway";"TRAF6 mediated IRF7 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulators of DDX58/IFIH1 signaling"
XP_011187383.1	18	KEGG: 00220+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00270+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-7383;KEGG: 00950+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00710+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00250+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00350+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00400+2.6.1.1	"Arginine biosynthesis";"Coenzyme M biosynthesis II";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism";"Sulfolactate degradation III";"Carbon fixation in photosynthetic organisms";"Novobiocin biosynthesis";"(R)-cysteate degradation";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tyrosine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Phenylalanine, tyrosine and tryptophan biosynthesis"
XP_011196198.1	2	MetaCyc: PWY-5381;KEGG: 00760+2.7.1.173+2.7.1.22	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_011195953.2	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_011178411.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase"
XP_028898213.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_011176818.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_054082559.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_054081828.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_054089757.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_011187069.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_028894912.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_011192635.2	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_011193226.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_011193559.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_028898265.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011194777.1	182	Reactome: R-HSA-209543;Reactome: R-HSA-2173791;Reactome: R-HSA-975163;Reactome: R-HSA-201681;Reactome: R-HSA-5678895;Reactome: R-HSA-8948747;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-9613829;Reactome: R-HSA-5676590;Reactome: R-HSA-936440;Reactome: R-HSA-174113;Reactome: R-HSA-912631;Reactome: R-HSA-5205685;Reactome: R-HSA-5696395;Reactome: R-HSA-2122948;Reactome: R-HSA-8876493;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-72695;Reactome: R-HSA-1295596;Reactome: R-HSA-211733;Reactome: R-HSA-175474;Reactome: R-HSA-179409;Reactome: R-HSA-450408;Reactome: R-HSA-2173796;Reactome: R-HSA-5610780;Reactome: R-HSA-182971;Reactome: R-HSA-937072;Reactome: R-HSA-9033241;Reactome: R-HSA-2644606;Reactome: R-HSA-2173788;Reactome: R-HSA-5693565;Reactome: R-HSA-450321;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-975144;Reactome: R-HSA-6783310;Reactome: R-HSA-72702;Reactome: R-HSA-2691232;Reactome: R-HSA-68949;Reactome: R-HSA-2979096;Reactome: R-HSA-936964;Reactome: R-HSA-72706;Reactome: R-HSA-382556;Reactome: R-HSA-9615710;Reactome: R-HSA-983168;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-156827;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-168638;Reactome: R-HSA-174084;Reactome: R-HSA-5685942;Reactome: R-HSA-977225;Reactome: R-HSA-8866654;Reactome: R-HSA-2559580;Reactome: R-HSA-9637628;Reactome: R-HSA-5689896;Reactome: R-HSA-69017;Reactome: R-HSA-9013507;Reactome: R-HSA-3322077;Reactome: R-HSA-5684264;Reactome: R-HSA-2565942;Reactome: R-HSA-5696400;Reactome: R-HSA-5632684;Reactome: R-HSA-4641258;Reactome: R-HSA-1236382;Reactome: R-HSA-180534;Reactome: R-HSA-8875360;Reactome: R-HSA-209560;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-1358803;Reactome: R-HSA-8854050;Reactome: R-HSA-975956;Reactome: R-HSA-937041;Reactome: R-HSA-975957;Reactome: R-HSA-937039;Reactome: R-HSA-4608870;Reactome: R-HSA-6804760;Reactome: R-HSA-8852276;Reactome: R-HSA-5656121;Reactome: R-HSA-5689877;Reactome: R-HSA-5607764;Reactome: R-HSA-156902;Reactome: R-HSA-2559585;Reactome: R-HSA-5689901;Reactome: R-HSA-168928;Reactome: R-HSA-2173795;Reactome: R-HSA-5357905;Reactome: R-HSA-5693607;Reactome: R-HSA-69601;Reactome: R-HSA-72689;Reactome: R-HSA-110314;Reactome: R-HSA-3785653;Reactome: R-HSA-2894862;Reactome: R-HSA-174048;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8866652;Reactome: R-HSA-9633012;Reactome: R-HSA-9646399;Reactome: R-HSA-4641263;Reactome: R-HSA-69231;Reactome: R-HSA-72649;Reactome: R-HSA-5658442;Reactome: R-HSA-2122947;Reactome: R-HSA-6804756;Reactome: R-HSA-917729;Reactome: R-HSA-2672351;Reactome: R-HSA-6781827;Reactome: R-HSA-9645460;Reactome: R-HSA-450302;Reactome: R-HSA-8856828;Reactome: R-HSA-195253;Reactome: R-HSA-2559582;Reactome: R-HSA-532668;Reactome: R-HSA-5654726;Reactome: R-HSA-5675221;Reactome: R-HSA-8863795;Reactome: R-HSA-5655862;Reactome: R-HSA-3134975;Reactome: R-HSA-3769402;Reactome: R-HSA-2871837;Reactome: R-HSA-1799339;Reactome: R-HSA-8939236;Reactome: R-HSA-975110;Reactome: R-HSA-5675482;Reactome: R-HSA-1169408;Reactome: R-HSA-1253288;Reactome: R-HSA-72764;Reactome: R-HSA-8951664;Reactome: R-HSA-162588;Reactome: R-HSA-8849469;Reactome: R-HSA-1234176;Reactome: R-HSA-168927;Reactome: R-HSA-901032;Reactome: R-HSA-5656169;Reactome: R-HSA-9604323;Reactome: R-HSA-174490;Reactome: R-HSA-8948751;Reactome: R-HSA-5654733;Reactome: R-HSA-9014325;Reactome: R-HSA-5357956;Reactome: R-HSA-4641257;Reactome: R-HSA-110320;Reactome: R-HSA-6804757;Reactome: R-HSA-937042;Reactome: R-HSA-9013973;Reactome: R-HSA-445989;Reactome: R-HSA-8856825;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-9636383;Reactome: R-HSA-68827;Reactome: R-HSA-5654732;Reactome: R-HSA-192823;Reactome: R-HSA-6782210;Reactome: R-HSA-5607761;Reactome: R-HSA-6791226;Reactome: R-HSA-5610783;Reactome: R-HSA-917937;Reactome: R-HSA-5610785;Reactome: R-HSA-5654727;Reactome: R-HSA-6807004;Reactome: R-HSA-174154;Reactome: R-HSA-5696394;Reactome: R-HSA-69541;Reactome: R-HSA-174184;Reactome: R-HSA-2408557;Reactome: R-HSA-400253;Reactome: R-HSA-75815;Reactome: R-HSA-205043	"p75NTR recruits signalling complexes";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TCF dependent signaling in response to WNT";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN localization";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Chaperone Mediated Autophagy";"NIK-->noncanonical NF-kB signaling";"Negative regulators of DDX58/IFIH1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of signaling by CBL";"Pink/Parkin Mediated Mitophagy";"Formation of Incision Complex in GG-NER";"Activated NOTCH1 Transmits Signal to the Nucleus";"InlA-mediated entry of Listeria monocytogenes into host cells";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Formation of the ternary complex, and subsequently, the 43S complex";"Spry regulation of FGF signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Assembly Of The HIV Virion";"APC-Cdc20 mediated degradation of Nek2A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Degradation of GLI1 by the proteasome";"EGFR downregulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Peroxisomal protein import";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Downregulation of TGF-beta receptor signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Fanconi Anemia Pathway";"Ribosomal scanning and start codon recognition";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Orc1 removal from chromatin";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ABC-family proteins mediated transport";"Late endosomal microautophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"L13a-mediated translational silencing of Ceruloplasmin expression";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"NOD1/2 Signaling Pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"HDR through Homologous Recombination (HRR)";"Amyloid fiber formation";"E3 ubiquitin ligases ubiquitinate target proteins";"Oxidative Stress Induced Senescence";"Modulation by Mtb of host immune system";"Ovarian tumor domain proteases";"CDK-mediated phosphorylation and removal of Cdc6";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Glycogen synthesis";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of PLK1 Activity at G2/M Transition";"Dual Incision in GG-NER";"Hedgehog 'on' state";"Degradation of DVL";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Vpu mediated degradation of CD4";"InlB-mediated entry of Listeria monocytogenes into host cell";"NF-kB is activated and signals survival";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Downregulation of ERBB2:ERBB3 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"IKK complex recruitment mediated by RIP1";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"IRAK1 recruits IKK complex";"Asymmetric localization of PCP proteins";"Regulation of TP53 Activity through Methylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translesion synthesis by POLI";"Josephin domain DUBs";"CLEC7A (Dectin-1) signaling";"Peptide chain elongation";"Oncogene Induced Senescence";"Metalloprotease DUBs";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Regulation of TNFR1 signaling";"Processing of DNA double-strand break ends";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Formation of a pool of free 40S subunits";"Recognition of DNA damage by PCNA-containing replication complex";"Myoclonic epilepsy of Lafora";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"APC/C:Cdc20 mediated degradation of Cyclin B";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aggrephagy";"Regulation of FZD by ubiquitination";"Cyclin D associated events in G1";"Translation initiation complex formation";"Regulation of RAS by GAPs";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of TP53 Activity through Phosphorylation";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Stimuli-sensing channels";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Alpha-protein kinase 1 signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Clathrin-mediated endocytosis";"Degradation of beta-catenin by the destruction complex";"Senescence-Associated Secretory Phenotype (SASP)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Negative regulation of FGFR1 signaling";"Negative regulation of MAPK pathway";"Downregulation of ERBB2 signaling";"Translesion synthesis by POLK";"Regulation of innate immune responses to cytosolic DNA";"Deactivation of the beta-catenin transactivating complex";"FCERI mediated NF-kB activation";"SRP-dependent cotranslational protein targeting to membrane";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Regulation of necroptotic cell death";"ISG15 antiviral mechanism";"Downregulation of ERBB4 signaling";"Eukaryotic Translation Termination";"Neddylation";"Budding and maturation of HIV virion";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TICAM1, RIP1-mediated IKK complex recruitment";"ER Quality Control Compartment (ERQC)";"Termination of translesion DNA synthesis";"Negative regulation of NOTCH4 signaling";"Membrane binding and targetting of GAG proteins";"Regulation of PTEN stability and activity";"Negative regulation of FGFR4 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"Degradation of AXIN";"Translesion Synthesis by POLH";"Regulation of TP53 Degradation";"IRAK2 mediated activation of TAK1 complex";"TICAM1-dependent activation of IRF3/IRF7";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Cargo recognition for clathrin-mediated endocytosis";"Separation of Sister Chromatids";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Prevention of phagosomal-lysosomal fusion";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of FGFR3 signaling";"Viral mRNA Translation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dectin-1 mediated noncanonical NF-kB signaling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Degradation of GLI2 by the proteasome";"Iron uptake and transport";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of FGFR2 signaling";"Negative regulation of MET activity";"APC/C:Cdc20 mediated degradation of Securin";"DNA Damage Recognition in GG-NER";"Stabilization of p53";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Selenocysteine synthesis";"Circadian Clock";"Ubiquitin-dependent degradation of Cyclin D";"NRIF signals cell death from the nucleus"
XP_054081980.1	18	MetaCyc: PWY-7416;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7417	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)"
XP_011188243.1	11	Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948	"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_011176759.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054082050.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation"
XP_054091594.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_011189018.1	4	Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903	"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Receptor Mediated Mitophagy"
XP_011196415.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_054089910.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_028898143.2	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054089952.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054082012.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054083569.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_054088826.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_054082404.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_028901452.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_011188808.1	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_011194957.2	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_054081815.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_028896888.1	3	Reactome: R-HSA-189085;Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"Digestion of dietary carbohydrate";"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054081614.1	12	MetaCyc: PWY-5667;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6118;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902;Reactome: R-HSA-1483166;Reactome: R-HSA-5368286;MetaCyc: PWY-7411	"CDP-diacylglycerol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"Synthesis of PA";"Mitochondrial translation initiation";"Phosphatidate biosynthesis (yeast)"
XP_011186903.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_054089684.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_028896019.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"T cell receptor signaling pathway";"Circadian Clock";"Th1 and Th2 cell differentiation"
XP_054088055.1	12	Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-447038;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308;Reactome: R-HSA-8849932	"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules"
XP_011190688.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_011189571.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012	"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_011187275.1	3	Reactome: R-HSA-5617472;Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_028895943.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054083581.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_011177403.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847	"Ub-specific processing proteases";"HATs acetylate histones"
XP_011196079.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937072	"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_011189025.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_011178743.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_011189670.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434	"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054086847.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_054089667.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_011184561.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627	"Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_028902036.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_011190740.2	2	Reactome: R-HSA-2151201;KEGG: 00970+6.1.1.14	"Transcriptional activation of mitochondrial biogenesis";"Aminoacyl-tRNA biosynthesis"
XP_054087238.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_011188351.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2"
XP_054088169.1	3	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions"
XP_054090537.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054082644.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_054088053.1	12	Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-451308	"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Long-term potentiation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor"
XP_054087560.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_011186905.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_054087327.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011185456.2	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_011193958.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684	"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism"
XP_054081813.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054089370.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_011180809.1	7	Reactome: R-HSA-2029485;KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1483148;MetaCyc: PWY-7039	"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Choline biosynthesis III";"Ether lipid metabolism";"Synthesis of PA";"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule"
XP_011178673.1	8	MetaCyc: PWY-6556;MetaCyc: PWY-7181;KEGG: 00983+3.5.4.5;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+3.5.4.5;MetaCyc: PWY-7199;Reactome: R-HSA-6798695	"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides degradation";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Neutrophil degranulation"
XP_028896063.2	14	Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-6798695;Reactome: R-HSA-9017802;Reactome: R-HSA-1474228;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-193692	"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Neutrophil degranulation";"Noncanonical activation of NOTCH3";"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR"
XP_028894626.2	56	Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-350562	"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)"
XP_011179408.2	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism"
XP_011187273.1	10	Reactome: R-HSA-72702;Reactome: R-HSA-72731;Reactome: R-HSA-382556;Reactome: R-HSA-72695;Reactome: R-HSA-9648895;Reactome: R-HSA-156827;Reactome: R-HSA-381042;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-9633012	"Ribosomal scanning and start codon recognition";"Recycling of eIF2:GDP";"ABC-family proteins mediated transport";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK1 (HRI) to heme deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"PERK regulates gene expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_054089274.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011191768.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054089827.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_054084002.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_011190704.1	4	Reactome: R-HSA-3371568;Reactome: R-HSA-3371497;Reactome: R-HSA-8939211;Reactome: R-HSA-9018519	"Attenuation phase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling";"Estrogen-dependent gene expression"
XP_054088789.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_011184988.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_054091944.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7036;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_011182559.1	6	KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11	"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism"
XP_054087661.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_011185489.2	3	Reactome: R-HSA-8878166;Reactome: R-HSA-6785807;Reactome: R-HSA-8939902	"Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity"
XP_011183873.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_011197113.2	11	MetaCyc: PWY-7782;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8052;KEGG: 00600+3.1.3.4;MetaCyc: PWY-6453;Reactome: R-HSA-2029485;KEGG: 00565+3.1.3.4	"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Sphingolipid metabolism";"Stigma estolide biosynthesis";"Role of phospholipids in phagocytosis";"Ether lipid metabolism"
XP_011189202.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553	"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs"
XP_028896705.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_054082843.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_011185071.1	11	KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675;Reactome: R-HSA-8964539;MetaCyc: PWY-6963;MetaCyc: PWY-381;Reactome: R-HSA-210455;MetaCyc: PWY-6964;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6549	"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle II";"Nitrogen metabolism";"L-glutamine biosynthesis III"
XP_011181618.2	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_054090388.1	6	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-76005	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+"
XP_054084747.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_054084223.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054083077.1	5	Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001	"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade"
XP_011182047.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_011181277.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011196346.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_054086916.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054082555.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_011178197.2	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054086098.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_011190996.2	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_011195171.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_054087656.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_054088332.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_011192147.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011180767.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_011192674.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_011192242.2	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_054085256.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_054086909.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054087434.1	24	Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-9009391;Reactome: R-HSA-428930;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-456926;Reactome: R-HSA-8964315;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-202040;Reactome: R-HSA-418217;Reactome: R-HSA-163359;Reactome: R-HSA-381676;Reactome: R-HSA-6814122;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-400042;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-8964616	"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"Extra-nuclear estrogen signaling";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through BTK";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"G-protein activation";"G beta:gamma signalling through PLC beta";"Glucagon signaling in metabolic regulation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through CDC42"
XP_028895476.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_011191354.2	5	Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
XP_011188872.2	6	KEGG: 00900+4.1.1.33;Reactome: R-HSA-191273;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;MetaCyc: PWY-922;Reactome: R-HSA-446199	"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Synthesis of Dolichyl-phosphate"
XP_028902152.1	3	KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_011177490.1	11	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Oxidative Stress Induced Senescence";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"Relaxin signaling pathway"
XP_054085798.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695;Reactome: R-HSA-432722;Reactome: R-HSA-8856825	"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis"
XP_028897049.2	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_011191462.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054085749.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_011179226.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011186850.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_028895728.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_054090688.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_054090830.1	17	Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-8951664;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-174048	"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Neddylation";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B"
XP_054090107.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_011179553.1	10	KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096	"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Galactose metabolism";"HS-GAG degradation"
XP_011182735.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011178981.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_028902226.2	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_054083565.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011192112.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_054084660.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011192150.1	6	Reactome: R-HSA-2046106;Reactome: R-HSA-1369062;Reactome: R-HSA-5684045;Reactome: R-HSA-390247;Reactome: R-HSA-2046105;Reactome: R-HSA-9603798	"alpha-linolenic acid (ALA) metabolism";"ABC transporters in lipid homeostasis";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Beta-oxidation of very long chain fatty acids";"Linoleic acid (LA) metabolism";"Class I peroxisomal membrane protein import"
XP_054091607.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_054086138.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_054086903.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054091188.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_011184585.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_054086540.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_028896732.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011184677.1	18	MetaCyc: PWY-6644;MetaCyc: PWY-6627;KEGG: 00760+2.4.2.1;MetaCyc: PWY-5532;MetaCyc: PWY-6609;Reactome: R-HSA-73614;MetaCyc: PWY-6611;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179-1;KEGG: 00240+2.4.2.3;MetaCyc: PWY-6608;MetaCyc: PWY-4202;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5695;MetaCyc: PWY-6620;Reactome: R-HSA-73621	"Fluoroacetate and fluorothreonine biosynthesis";"Salinosporamide A biosynthesis";"Nicotinate and nicotinamide metabolism";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage III";"Pyrimidine salvage";"Adenine and adenosine salvage V";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Drug metabolism - other enzymes";"Inosine 5'-phosphate degradation";"Guanine and guanosine salvage";"Pyrimidine catabolism"
XP_054085283.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-432040	"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (s) signalling events";"G alpha (z) signalling events";"Purine metabolism";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_011178638.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_011184225.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events"
XP_011188169.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054088351.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_054086641.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054087732.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_028898215.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_011180482.2	2	KEGG: 00970+6.1.1.9;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_011183581.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054086259.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054085587.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011179404.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_028896842.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
XP_011183528.2	5	Reactome: R-HSA-936440;Reactome: R-HSA-936964;Reactome: R-HSA-933541;Reactome: R-HSA-9013973;Reactome: R-HSA-918233	"Negative regulators of DDX58/IFIH1 signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6 mediated IRF7 activation";"TICAM1-dependent activation of IRF3/IRF7";"TRAF3-dependent IRF activation pathway"
XP_011188840.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011194505.2	9	MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism"
XP_054088086.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054089856.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_054088922.1	6	KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-6952;MetaCyc: PWY-4261	"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerol degradation I"
XP_011182152.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054088165.1	3	Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_011181707.1	10	Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-6798695;Reactome: R-HSA-6804756	"Signal transduction by L1";"Synthesis of PC";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Neutrophil degranulation";"Regulation of TP53 Activity through Phosphorylation"
XP_011190154.2	12	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-381038;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-380320	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"XBP1(S) activates chaperone genes";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes"
XP_011176975.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011184511.2	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_011186255.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_011178427.2	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_011191436.2	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_011188826.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011183569.1	7	KEGG: 00550+2.7.8.13;MetaCyc: PWY-6470;Reactome: R-HSA-4549356;Reactome: R-HSA-446193;MetaCyc: PWY-5265;KEGG: 00510+2.7.8.15;MetaCyc: PWY-6471	"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)"
XP_028896069.2	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_011197106.2	9	KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52	"Other glycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series"
XP_054088808.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-418555	"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (z) signalling events";"G alpha (s) signalling events"
XP_054081368.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011194566.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_011196930.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_011187311.2	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_011196741.1	57	Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-69017	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6"
XP_054088059.1	12	KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-9609736	"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors"
XP_054084589.1	7	KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-2301;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25	"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism"
XP_054089889.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_054081409.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_054087590.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_011181734.2	15	Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128	"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling"
XP_054085291.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011184309.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764	"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination"
XP_011184055.2	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_011184443.1	5	Reactome: R-HSA-2022928;MetaCyc: PWY-6558;Reactome: R-HSA-3656253;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656237	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT2 causes exostoses 2"
XP_054092130.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_011178853.2	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_011192003.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_011190812.1	34	Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-9639288;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531	"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"RHO GTPases Activate Formins";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amino acids regulate mTORC1";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus"
XP_054086811.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_011192183.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054081416.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_011187509.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_028894215.2	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_011193271.2	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_011195668.1	3	Reactome: R-HSA-3065676;Reactome: R-HSA-3065678;Reactome: R-HSA-983168	"SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_028894419.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_011184316.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_011187752.1	7	KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-2301;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25	"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis"
XP_011179103.1	12	MetaCyc: PWY-7901;MetaCyc: PWY-1187;MetaCyc: PWY-6842;KEGG: 00270+4.4.1.13;MetaCyc: PWY-601;KEGG: 00450+4.4.1.13;KEGG: 00380+2.6.1.7;Reactome: R-HSA-71240;MetaCyc: PWY-6309;MetaCyc: PWY-801;MetaCyc: PWY-2821;MetaCyc: PWY-6936	"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tryptophan";"Selenocompound metabolism";"Tryptophan metabolism";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)"
XP_054083949.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_054081171.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_011190990.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_011179759.2	24	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2871837;KEGG: 04926+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-114604;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-165158;Reactome: R-HSA-392451;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-5607764;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-2730905;Reactome: R-HSA-5625740;Reactome: R-HSA-202424;Reactome: R-HSA-354192;Reactome: R-HSA-444257;Reactome: R-HSA-5218921	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"FCERI mediated NF-kB activation";"Relaxin signaling pathway";"CD28 dependent PI3K/Akt signaling";"GPVI-mediated activation cascade";"PI3K-Akt signaling pathway";"PIP3 activates AKT signaling";"Activation of AKT2";"G beta:gamma signalling through PI3Kgamma";"Thermogenesis";"Estrogen-stimulated signaling through PRKCZ";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"Role of LAT2/NTAL/LAB on calcium mobilization";"RHO GTPases activate PKNs";"Downstream TCR signaling";"Integrin signaling";"RSK activation";"VEGFR2 mediated cell proliferation"
XP_011195758.1	5	MetaCyc: PWY-7204;Reactome: R-HSA-6798695;KEGG: 00750+2.7.1.35;Reactome: R-HSA-964975;MetaCyc: PWY-7282	"Pyridoxal 5'-phosphate salvage II (plants)";"Neutrophil degranulation";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_011189286.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011180810.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054086388.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_054081649.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_028897772.2	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_028901779.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_011185725.2	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_011194015.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_028895873.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_011178450.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011184603.1	10	Reactome: R-HSA-201722;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Formation of the beta-catenin:TCF transactivating complex";"PI3K-Akt signaling pathway";"HATs acetylate histones";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Ub-specific processing proteases";"Thermogenesis";"mTOR signaling pathway"
XP_054084119.1	9	MetaCyc: PWY-7039;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-8052;Reactome: R-HSA-416476;MetaCyc: PWY-6367	"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism"
XP_054091673.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602	"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_011179814.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054082237.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011192441.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis"
XP_011195939.2	9	Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_011178412.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_054082533.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011178004.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_028899888.2	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_054082606.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_011176472.2	22	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-432142;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-389513	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"RAF activation";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Platelet sensitization by LDL";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling"
XP_054081251.1	5	MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_011193539.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_011177314.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_011179979.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011187336.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_011177252.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054091525.1	7	MetaCyc: PWY-7841;KEGG: 00600+2.4.1.80;MetaCyc: PWY-5129;Reactome: R-HSA-1660662;MetaCyc: PWY-7838;MetaCyc: PWY-7839;MetaCyc: PWY-7836	"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Glycosphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis"
XP_011184730.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_054088696.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011177210.1	5	Reactome: R-HSA-532668;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7918;MetaCyc: PWY-7919;Reactome: R-HSA-4793954	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (yeast)";"Protein N-glycosylation processing phase (plants and animals)";"Defective MOGS causes MOGS-CDG (CDG-2b)"
XP_011192595.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_011190905.1	19	Reactome: R-HSA-6798695;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;Reactome: R-HSA-75105;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;MetaCyc: PWY-5538;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5392;Reactome: R-HSA-163765;MetaCyc: PWY-5172;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00020+2.3.3.8;MetaCyc: PWY-7384	"Neutrophil degranulation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"ChREBP activates metabolic gene expression";"Acetyl-coa biosynthesis III (from citrate)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_011182938.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054081775.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119	"Sphingolipid metabolism";"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_054088837.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054083595.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054088100.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-418597	"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (s) signalling events";"G alpha (z) signalling events"
XP_054087391.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054090401.1	6	Reactome: R-HSA-76005;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597	"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"G alpha (z) signalling events"
XP_054084445.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_011184616.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_054084690.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054091915.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_011177828.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_011181345.1	1	Reactome: R-HSA-419771	"Opsins"
XP_054085594.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_054089951.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_011195021.2	3	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_054082190.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011197080.2	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_028898248.2	5	Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-5218920	"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability"
XP_011195687.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011179328.1	57	Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-450408	"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Neutrophil degranulation";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_011176600.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_011185447.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_011188921.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation"
XP_011182369.2	4	Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-2129379	"Integrin cell surface interactions";"ECM proteoglycans";"Syndecan interactions";"Molecules associated with elastic fibres"
XP_011187095.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_011181959.2	3	Reactome: R-HSA-3214841;Reactome: R-HSA-6804760;Reactome: R-HSA-2299718	"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes"
XP_054081643.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_011194790.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_028895528.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_011188423.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_054092090.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_011190508.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_011190847.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_054083943.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_011186233.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_011176954.1	4	MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268	"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_054083582.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054090526.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_028894413.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_011181252.3	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054084605.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011178236.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-198323;Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-8854214	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"AKT phosphorylates targets in the cytosol";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"TBC/RABGAPs"
XP_011188352.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
XP_011179109.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_028894567.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_011177815.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_028896532.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054087099.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Aggrephagy";"Mitotic Prometaphase";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_028898357.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_011192009.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_011180419.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_028895335.2	11	Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1	"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"G alpha (s) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Purine metabolism"
XP_028898482.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_028893880.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_011185607.1	8	MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism"
XP_054087133.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-3301854	"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"snRNP Assembly";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly"
XP_011186708.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011184303.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054092111.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_028894346.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_011187000.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_011189572.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764	"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination"
XP_011189134.1	2	Reactome: R-HSA-5578999;Reactome: R-HSA-174403	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling"
XP_054083945.1	29	MetaCyc: PWY-6871;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-6587;KEGG: 00980+1.1.1.1;KEGG: 00982+1.1.1.1;MetaCyc: PWY-5751;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5078;KEGG: 00592+1.1.1.1;KEGG: 00071+1.1.1.1;MetaCyc: PWY-3162;MetaCyc: PWY-5057;MetaCyc: PWY-6313;KEGG: 00010+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-7396;MetaCyc: PWY-7111;MetaCyc: PWY-6342;MetaCyc: PWY-5082;MetaCyc: PWY-5076;MetaCyc: PWY-5486;MetaCyc: PWY-6802;KEGG: 00260+1.1.1.1;MetaCyc: PWY-7013;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00626+1.1.1.1;MetaCyc: PWY-6333	"3-methylbutanol biosynthesis (engineered)";"Tyrosine metabolism";"L-phenylalanine degradation III";"Pyruvate fermentation to ethanol III";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Phenylethanol biosynthesis";"Retinol metabolism";"L-isoleucine degradation II";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"L-tryptophan degradation V (side chain pathway)";"L-valine degradation II";"Serotonin degradation";"Glycolysis / Gluconeogenesis";"Chitin degradation to ethanol";"Butanol and isobutanol biosynthesis (engineered)";"Pyruvate fermentation to isobutanol (engineered)";"Noradrenaline and adrenaline degradation";"L-methionine degradation III";"L-leucine degradation III";"Pyruvate fermentation to ethanol II";"Salidroside biosynthesis";"Glycine, serine and threonine metabolism";"(S)-propane-1,2-diol degradation";"Chloroalkane and chloroalkene degradation";"Pyruvate fermentation to ethanol I";"Naphthalene degradation";"Acetaldehyde biosynthesis I"
XP_054084001.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_011186388.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_011187178.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_054084536.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_011188917.2	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_054085944.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_011185072.1	11	MetaCyc: PWY-6549;Reactome: R-HSA-210455;MetaCyc: PWY-6964;KEGG: 00910+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-6963;MetaCyc: PWY-5675;Reactome: R-HSA-8964539;KEGG: 00250+6.3.1.2;KEGG: 00630+6.3.1.2;KEGG: 00220+6.3.1.2	"L-glutamine biosynthesis III";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle II";"Nitrogen metabolism";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle I";"Nitrate reduction V (assimilatory)";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Glyoxylate and dicarboxylate metabolism";"Arginine biosynthesis"
XP_054084603.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054087662.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_054090676.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_011183161.2	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_011177296.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14	"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis"
XP_028899361.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_028899275.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_028898851.1	4	Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism"
XP_011189508.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_028896662.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054082103.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_011184727.2	7	MetaCyc: PWY-7158;MetaCyc: PWY-6134;KEGG: 00360+1.14.16.1;KEGG: 00790+1.14.16.1;KEGG: 00400+1.14.16.1;Reactome: R-HSA-2160456;Reactome: R-HSA-8964208	"L-phenylalanine degradation V";"L-tyrosine biosynthesis IV";"Phenylalanine metabolism";"Folate biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylketonuria";"Phenylalanine metabolism"
XP_011179472.3	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_054086342.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_011197039.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_054091176.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011186478.2	4	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-499943;Reactome: R-HSA-2161541	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism"
XP_011178729.2	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_011183355.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_011177364.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054083593.1	3	KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451;MetaCyc: PWY-7856	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme a biosynthesis"
XP_054086158.1	9	Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-1971475	"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054082814.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_011179237.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_028896710.2	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054083111.1	14	MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166	"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Synthesis of PA"
XP_011181409.1	12	Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167243	"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery"
XP_011192686.2	16	Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553	"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs"
XP_011178598.2	56	Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168	"Degradation of DVL";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011181205.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_028897018.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011179606.1	7	Reactome: R-HSA-373753;Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"Nephrin family interactions";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_011194006.1	4	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054083297.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_011188561.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054087710.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_028902011.2	6	KEGG: 00520+5.4.2.3;MetaCyc: PWY-5514;Reactome: R-HSA-446210;MetaCyc: PWY-6749;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.10	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism"
XP_011190916.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_028900927.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054081645.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054087509.1	2	Reactome: R-HSA-5654726;Reactome: R-HSA-190373	"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation"
XP_028893839.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054084316.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_011195172.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012	"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_011196168.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_054091020.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054087636.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054086642.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054091587.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_011190746.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_054088352.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_054086537.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_011182085.2	3	Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45	"Glycosphingolipid metabolism";"Other glycan degradation";"Sphingolipid metabolism"
XP_054087503.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_054087940.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054091906.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_054087207.1	29	Reactome: R-HSA-176187;Reactome: R-HSA-5358606;Reactome: R-HSA-110320;Reactome: R-HSA-174437;Reactome: R-HSA-68962;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-3108214;Reactome: R-HSA-5696397;Reactome: R-HSA-3371453;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-912446;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-6783310;Reactome: R-HSA-3371511;Reactome: R-HSA-5685938	"Activation of ATR in response to replication stress";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate from the C-strand";"Activation of the pre-replicative complex";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"SUMOylation of DNA damage response and repair proteins";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of HSF1-mediated heat shock response";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"Meiotic recombination";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Fanconi Anemia Pathway";"HSF1 activation";"HDR through Single Strand Annealing (SSA)"
XP_011182868.1	5	Reactome: R-HSA-1834949;Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571	"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)"
XP_011182319.1	16	Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-2467813	"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids"
XP_054088310.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_054090508.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_011188195.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902	"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation"
XP_054082535.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011190526.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_011183582.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054086233.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054091564.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054091523.1	7	MetaCyc: PWY-7841;KEGG: 00600+2.4.1.80;MetaCyc: PWY-5129;Reactome: R-HSA-1660662;MetaCyc: PWY-7839;MetaCyc: PWY-7838;MetaCyc: PWY-7836	"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Glycosphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis"
XP_011194510.1	9	MetaCyc: PWY-6118;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7385;MetaCyc: PWY-5667;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.94	"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism"
XP_028899705.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054084498.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-6453	"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis"
XP_011186830.1	8	KEGG: 00950+1.14.16.2;MetaCyc: PWY-5049;KEGG: 00350+1.14.16.2;MetaCyc: PWY-3581;KEGG: 00790+1.14.16.2;MetaCyc: PWY-5394;MetaCyc: PWY-6133;Reactome: R-HSA-209905	"Isoquinoline alkaloid biosynthesis";"Rosmarinic acid biosynthesis II";"Tyrosine metabolism";"(S)-reticuline biosynthesis I";"Folate biosynthesis";"Betalamic acid biosynthesis";"(S)-reticuline biosynthesis II";"Catecholamine biosynthesis"
XP_011186280.2	15	Reactome: R-HSA-9634285;Reactome: R-HSA-1227986;Reactome: R-HSA-9665249;Reactome: R-HSA-9665246;Reactome: R-HSA-9665233;Reactome: R-HSA-9665245;Reactome: R-HSA-9664565;Reactome: R-HSA-9665247;Reactome: R-HSA-5637810;Reactome: R-HSA-9652282;Reactome: R-HSA-9665251;Reactome: R-HSA-1236382;Reactome: R-HSA-8863795;Reactome: R-HSA-9665250;Reactome: R-HSA-9665244	"Constitutive Signaling by Overexpressed ERBB2";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to tesevatinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to osimertinib";"Constitutive Signaling by EGFRvIII";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to sapitinib"
XP_054091919.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_054085236.1	3	Reactome: R-HSA-70350;Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3	"Fructose catabolism";"Essential fructosuria";"Fructose and mannose metabolism"
XP_054083807.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_054081779.1	4	Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;MetaCyc: PWY-7119	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_011196295.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011190138.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_028896731.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054083548.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_011192593.1	13	KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Hyaluronan uptake and degradation";"CS/DS degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism"
XP_054088487.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_011182306.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_011187647.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011193615.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_054091227.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011178142.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_011186546.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_028896940.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011194273.2	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_011178358.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_011191915.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_028898608.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_011179271.2	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_011184651.2	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_054082109.1	4	MetaCyc: PWY-7887;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-6823	"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_011187254.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_011194234.1	7	Reactome: R-HSA-389661;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;KEGG: 00010+2.3.1.12;Reactome: R-HSA-70268;KEGG: 00620+2.3.1.12;KEGG: 00020+2.3.1.12	"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate metabolism";"Citrate cycle (TCA cycle)"
XP_054084609.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_011179105.1	12	MetaCyc: PWY-2821;MetaCyc: PWY-6936;Reactome: R-HSA-71240;KEGG: 00380+2.6.1.7;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6309;MetaCyc: PWY-801;MetaCyc: PWY-6842;KEGG: 00270+4.4.1.13;MetaCyc: PWY-601;MetaCyc: PWY-1187;MetaCyc: PWY-7901	"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)";"Tryptophan catabolism";"Tryptophan metabolism";"Selenocompound metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Homocysteine and cysteine interconversion";"Glutathione-mediated detoxification II";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tyrosine"
XP_054088921.1	6	Reactome: R-HSA-163560;MetaCyc: PWY-6952;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3	"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerol degradation I";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism"
XP_054085447.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_011182190.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_028894463.2	11	Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-5610787	"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (z) signalling events";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state"
XP_028894424.2	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_011196200.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_028898164.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_011181800.2	5	Reactome: R-HSA-5620924;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Intraflagellar transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_054081738.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_011184512.2	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_054086356.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_054086155.1	9	Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928	"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis"
XP_011182939.1	10	Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11	"Glycolysis";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism"
XP_011196059.1	14	MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166	"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Synthesis of PA"
XP_011181843.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_011186475.2	4	Reactome: R-HSA-499943;Reactome: R-HSA-2161541;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_011195628.2	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_028898366.2	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011196632.1	3	MetaCyc: PWY-6558;Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_011180942.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_011184129.1	13	Reactome: R-HSA-2206308;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;Reactome: R-HSA-4341670;MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;Reactome: R-HSA-4085001;KEGG: 00052+3.2.1.23	"MPS IV - Morquio syndrome B";"Other glycan degradation";"HS-GAG degradation";"Sphingolipid metabolism";"Defective NEU1 causes sialidosis";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Sialic acid metabolism";"Galactose metabolism"
XP_011188265.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_011185441.2	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_011189612.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_054090391.1	6	Reactome: R-HSA-114516;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-5099900	"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4"
XP_011179978.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_028899889.2	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_011193140.1	52	Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-5578749;Reactome: R-HSA-76071;Reactome: R-HSA-72163;Reactome: R-HSA-113418;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-6782135;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-6781823;Reactome: R-HSA-5601884;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-1834949;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-76061;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-76066;Reactome: R-HSA-9018519;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-73980;Reactome: R-HSA-203927;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-5250924;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-72203	"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"mRNA Splicing - Major Pathway";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of TC-NER Pre-Incision Complex";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Estrogen-dependent gene expression";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Termination";"MicroRNA (miRNA) biogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"B-WICH complex positively regulates rRNA expression";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Processing of Capped Intron-Containing Pre-mRNA"
XP_054092170.1	22	Reactome: R-HSA-389513;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-195253	"CTLA4 inhibitory signaling";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex"
XP_011188143.1	5	MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;Reactome: R-HSA-446210	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine"
XP_054088281.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011190095.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-3214858;Reactome: R-HSA-6804760	"snRNP Assembly";"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation"
XP_011183436.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_011196783.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_011189139.2	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_011180747.2	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_011194388.2	6	Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
XP_054088620.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_011180002.2	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_011192004.2	19	Reactome: R-HSA-8963888;Reactome: R-HSA-975634;Reactome: R-HSA-5686938;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-8957275;Reactome: R-HSA-3000497;Reactome: R-HSA-202733;Reactome: R-HSA-8866423;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-3000484;Reactome: R-HSA-3000480;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-432142;Reactome: R-HSA-8963901	"Chylomicron assembly";"Retinoid metabolism and transport";"Regulation of TLR by endogenous ligand";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"Post-translational protein phosphorylation";"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall";"VLDL assembly";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"LDL clearance";"Clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"Scavenging by Class A Receptors";"VLDL clearance";"Scavenging by Class B Receptors";"Platelet sensitization by LDL";"Chylomicron remodeling"
XP_011189551.1	8	Reactome: R-HSA-9636467;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-167590;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-182218	"Blockage of phagosome acidification";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Nef Mediated CD8 Down-regulation"
XP_011184851.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161	"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation"
XP_011187255.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_011195759.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_054086389.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_011181036.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_054081648.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_028901778.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054085422.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-163359	"G alpha (z) signalling events";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation"
XP_054088406.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_011190636.1	5	MetaCyc: PWY-7511;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"Protein ubiquitination";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_011186019.2	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228	"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix"
XP_011179477.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054083999.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_054087641.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_054082070.1	6	MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143	"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis"
XP_054082625.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054090822.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054090048.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_011188481.2	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_011193318.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054083948.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_011190940.1	4	Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-982772	"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Growth hormone receptor signaling"
XP_011180195.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_054087043.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054091923.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_011187508.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_011194910.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_011183787.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_028900712.1	25	Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-380270;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Gap junction assembly";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Recruitment of mitotic centrosome proteins and complexes";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_054087526.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_054083121.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054088419.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054082496.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_011178706.2	8	KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1	"Galactose metabolism";"Starch and sucrose metabolism";"Glycolysis";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_011193579.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_028893875.2	7	MetaCyc: PWY-7511;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-983168;Reactome: R-HSA-69473;Reactome: R-HSA-5693565	"Protein ubiquitination";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_054081408.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_054091639.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054088263.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054091484.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_054086434.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_011185189.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_011179865.1	40	Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-203927;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-5578749;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-6782135;Reactome: R-HSA-168325;Reactome: R-HSA-72165;Reactome: R-HSA-6803529;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-5601884;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-6781827	"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"Dual incision in TC-NER";"Viral Messenger RNA Synthesis";"mRNA Splicing - Minor Pathway";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_011193935.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_028898976.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_011194107.2	26	Reactome: R-HSA-918233;Reactome: R-HSA-9013508;Reactome: R-HSA-3371568;Reactome: R-HSA-201722;Reactome: R-HSA-9617629;Reactome: R-HSA-933541;Reactome: R-HSA-5621575;Reactome: R-HSA-1989781;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-5617472;Reactome: R-HSA-2122947;Reactome: R-HSA-8866907;Reactome: R-HSA-3134973;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-9614657;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-3899300;Reactome: R-HSA-3214847;Reactome: R-HSA-1368082	"TRAF3-dependent IRF activation pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"Attenuation phase";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of FOXO transcriptional activity by acetylation";"TRAF6 mediated IRF7 activation";"CD209 (DC-SIGN) signaling";"PPARA activates gene expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SUMOylation of transcription cofactors";"HATs acetylate histones";"RORA activates gene expression"
XP_054090590.1	7	Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation"
XP_028898605.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_011180418.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_011190710.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_011189312.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_028895749.2	4	Reactome: R-HSA-8849175;Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Threonine catabolism";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_054084482.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_054090691.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_054087098.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497	"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Aggrephagy";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_054091467.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398	"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway"
XP_011178998.2	4	MetaCyc: PWY-7286;MetaCyc: PWY-7285;Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_011179108.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_054081735.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054091217.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_011192999.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054092040.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_011180561.2	4	KEGG: 00534+2.4.2.26;MetaCyc: PWY-6557;KEGG: 00532+2.4.2.26;Reactome: R-HSA-1971475	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_011193625.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_011192886.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_028896909.2	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_054091191.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_011178189.1	4	MetaCyc: PWY-8040;MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072	"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Alanine racemization"
XP_054088877.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_011180970.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_011181958.2	3	Reactome: R-HSA-3214841;Reactome: R-HSA-6804760;Reactome: R-HSA-2299718	"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes"
XP_011187045.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011187453.2	3	MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403	"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_011182021.1	3	Reactome: R-HSA-1660661;Reactome: R-HSA-6798695;Reactome: R-HSA-9609523	"Sphingolipid de novo biosynthesis";"Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054084721.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_011182368.2	4	Reactome: R-HSA-2129379;Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-216083	"Molecules associated with elastic fibres";"ECM proteoglycans";"Syndecan interactions";"Integrin cell surface interactions"
XP_011181739.1	13	MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_028898249.2	5	Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400	"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_054090505.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_054085359.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011188198.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_028899370.2	17	MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;MetaCyc: PWY-4381;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-200425;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;Reactome: R-HSA-196780;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5743;Reactome: R-HSA-3371599;MetaCyc: PWY-5789;KEGG: 00640+6.4.1.2;KEGG: 00254+6.4.1.2;KEGG: 00720+6.4.1.2	"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Candicidin biosynthesis";"Carnitine metabolism";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Biotin transport and metabolism";"Glyoxylate assimilation";"Pyruvate metabolism";"3-hydroxypropanoate cycle";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propanoate metabolism";"Aflatoxin biosynthesis";"Carbon fixation pathways in prokaryotes"
XP_011180229.2	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_011196789.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011179431.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_011193314.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011186884.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_011187676.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_011177829.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_011178161.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_011180750.2	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054084640.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_028899708.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054081110.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule"
XP_011188517.2	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_028902067.2	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_054085724.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_054081152.1	19	Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-3000484;Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-8964026;Reactome: R-HSA-8964038;Reactome: R-HSA-8866423;Reactome: R-HSA-381426;Reactome: R-HSA-202733;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-8957275;Reactome: R-HSA-8856825;Reactome: R-HSA-5686938;Reactome: R-HSA-975634;Reactome: R-HSA-8963888	"Chylomicron remodeling";"Platelet sensitization by LDL";"VLDL clearance";"Scavenging by Class B Receptors";"Scavenging by Class F Receptors";"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"Chylomicron clearance";"LDL clearance";"VLDL assembly";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cell surface interactions at the vascular wall";"LDL remodeling";"Scavenging by Class H Receptors";"Post-translational protein phosphorylation";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Retinoid metabolism and transport";"Chylomicron assembly"
XP_028894527.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054083184.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011192714.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_011182933.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs"
XP_054082325.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_011196053.1	14	Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-7782	"Synthesis of PA";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen biosynthesis"
XP_011185781.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_054081894.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_011187043.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011196169.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_011178659.1	8	MetaCyc: PWY-7980;Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2	"ATP biosynthesis";"Transferrin endocytosis and recycling";"Oxidative phosphorylation";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Photosynthesis"
XP_011194889.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_028896201.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-456926	"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_011187259.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054089044.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_054086821.1	13	MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52	"Anhydromuropeptides recycling II";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_011180464.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_011188406.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_054082387.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73779	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_054083040.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_011183886.1	179	Reactome: R-HSA-6791226;Reactome: R-HSA-5607761;Reactome: R-HSA-6782210;Reactome: R-HSA-192823;Reactome: R-HSA-174154;Reactome: R-HSA-6807004;Reactome: R-HSA-5696394;Reactome: R-HSA-5654727;Reactome: R-HSA-5610785;Reactome: R-HSA-917937;Reactome: R-HSA-5610783;Reactome: R-HSA-69541;Reactome: R-HSA-205043;Reactome: R-HSA-75815;Reactome: R-HSA-400253;Reactome: R-HSA-2408557;Reactome: R-HSA-174184;Reactome: R-HSA-937042;Reactome: R-HSA-6804757;Reactome: R-HSA-110320;Reactome: R-HSA-8856825;Reactome: R-HSA-445989;Reactome: R-HSA-9013973;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-5654732;Reactome: R-HSA-68827;Reactome: R-HSA-9636383;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-8849469;Reactome: R-HSA-168927;Reactome: R-HSA-1234176;Reactome: R-HSA-5654733;Reactome: R-HSA-8948751;Reactome: R-HSA-174490;Reactome: R-HSA-9604323;Reactome: R-HSA-5656169;Reactome: R-HSA-901032;Reactome: R-HSA-5357956;Reactome: R-HSA-4641257;Reactome: R-HSA-9014325;Reactome: R-HSA-5675482;Reactome: R-HSA-1169408;Reactome: R-HSA-1253288;Reactome: R-HSA-72764;Reactome: R-HSA-162588;Reactome: R-HSA-8951664;Reactome: R-HSA-2559582;Reactome: R-HSA-532668;Reactome: R-HSA-5654726;Reactome: R-HSA-5655862;Reactome: R-HSA-8863795;Reactome: R-HSA-5675221;Reactome: R-HSA-2871837;Reactome: R-HSA-3769402;Reactome: R-HSA-3134975;Reactome: R-HSA-975110;Reactome: R-HSA-8939236;Reactome: R-HSA-1799339;Reactome: R-HSA-5658442;Reactome: R-HSA-917729;Reactome: R-HSA-6804756;Reactome: R-HSA-2122947;Reactome: R-HSA-6781827;Reactome: R-HSA-450302;Reactome: R-HSA-9645460;Reactome: R-HSA-2672351;Reactome: R-HSA-195253;Reactome: R-HSA-8856828;Reactome: R-HSA-3785653;Reactome: R-HSA-2894862;Reactome: R-HSA-110314;Reactome: R-HSA-8866652;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-174048;Reactome: R-HSA-4641263;Reactome: R-HSA-9646399;Reactome: R-HSA-9633012;Reactome: R-HSA-69231;Reactome: R-HSA-5607764;Reactome: R-HSA-5689877;Reactome: R-HSA-168928;Reactome: R-HSA-5689901;Reactome: R-HSA-2559585;Reactome: R-HSA-156902;Reactome: R-HSA-2173795;Reactome: R-HSA-72689;Reactome: R-HSA-69601;Reactome: R-HSA-5693607;Reactome: R-HSA-5357905;Reactome: R-HSA-5632684;Reactome: R-HSA-5696400;Reactome: R-HSA-180534;Reactome: R-HSA-1236382;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-1358803;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-209560;Reactome: R-HSA-8875360;Reactome: R-HSA-5656121;Reactome: R-HSA-8852276;Reactome: R-HSA-6804760;Reactome: R-HSA-937039;Reactome: R-HSA-975957;Reactome: R-HSA-4608870;Reactome: R-HSA-937041;Reactome: R-HSA-975956;Reactome: R-HSA-69017;Reactome: R-HSA-9013507;Reactome: R-HSA-5689896;Reactome: R-HSA-9637628;Reactome: R-HSA-3322077;Reactome: R-HSA-2565942;Reactome: R-HSA-5684264;Reactome: R-HSA-5685942;Reactome: R-HSA-174084;Reactome: R-HSA-168638;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-977225;Reactome: R-HSA-8866654;Reactome: R-HSA-2559580;Reactome: R-HSA-72706;Reactome: R-HSA-936964;Reactome: R-HSA-2979096;Reactome: R-HSA-382556;Reactome: R-HSA-6781823;Reactome: R-HSA-983168;Reactome: R-HSA-9615710;Reactome: R-HSA-156827;Reactome: R-HSA-6782135;Reactome: R-HSA-937072;Reactome: R-HSA-182971;Reactome: R-HSA-2173788;Reactome: R-HSA-2644606;Reactome: R-HSA-9033241;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-450321;Reactome: R-HSA-5693565;Reactome: R-HSA-68949;Reactome: R-HSA-2691232;Reactome: R-HSA-6783310;Reactome: R-HSA-975144;Reactome: R-HSA-5689603;Reactome: R-HSA-179409;Reactome: R-HSA-5610780;Reactome: R-HSA-2173796;Reactome: R-HSA-450408;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-1295596;Reactome: R-HSA-175474;Reactome: R-HSA-8948747;Reactome: R-HSA-5678895;Reactome: R-HSA-201681;Reactome: R-HSA-975163;Reactome: R-HSA-2173791;Reactome: R-HSA-209543;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-912631;Reactome: R-HSA-5676590;Reactome: R-HSA-936440;Reactome: R-HSA-9613829;Reactome: R-HSA-1169091;Reactome: R-HSA-2122948;Reactome: R-HSA-8876493;Reactome: R-HSA-5696395;Reactome: R-HSA-5205685	"Major pathway of rRNA processing in the nucleolus and cytosol";"Dectin-1 mediated noncanonical NF-kB signaling";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Viral mRNA Translation";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of MET activity";"DNA Damage Recognition in GG-NER";"Negative regulation of FGFR2 signaling";"GLI3 is processed to GLI3R by the proteasome";"Iron uptake and transport";"Degradation of GLI2 by the proteasome";"Stabilization of p53";"NRIF signals cell death from the nucleus";"Ubiquitin-dependent degradation of Cyclin D";"Circadian Clock";"Selenocysteine synthesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"IRAK2 mediated activation of TAK1 complex";"Regulation of TP53 Degradation";"Translesion Synthesis by POLH";"Cargo recognition for clathrin-mediated endocytosis";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1-dependent activation of IRF3/IRF7";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Separation of Sister Chromatids";"Negative regulation of FGFR3 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Prevention of phagosomal-lysosomal fusion";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"TICAM1, RIP1-mediated IKK complex recruitment";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of FGFR4 signaling";"Regulation of PTEN stability and activity";"Membrane binding and targetting of GAG proteins";"Negative regulation of NOTCH4 signaling";"Termination of translesion DNA synthesis";"ER Quality Control Compartment (ERQC)";"TNFR1-induced NFkappaB signaling pathway";"Degradation of AXIN";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Regulation of necroptotic cell death";"ISG15 antiviral mechanism";"Downregulation of ERBB4 signaling";"Eukaryotic Translation Termination";"Budding and maturation of HIV virion";"Neddylation";"Senescence-Associated Secretory Phenotype (SASP)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Negative regulation of FGFR1 signaling";"Translesion synthesis by POLK";"Downregulation of ERBB2 signaling";"Negative regulation of MAPK pathway";"FCERI mediated NF-kB activation";"Deactivation of the beta-catenin transactivating complex";"Regulation of innate immune responses to cytosolic DNA";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of RAS by GAPs";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Regulation of TP53 Activity through Phosphorylation";"NOTCH1 Intracellular Domain Regulates Transcription";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"activated TAK1 mediates p38 MAPK activation";"Alpha-protein kinase 1 signaling pathway";"Stimuli-sensing channels";"Degradation of beta-catenin by the destruction complex";"Clathrin-mediated endocytosis";"Myoclonic epilepsy of Lafora";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Recognition of DNA damage by PCNA-containing replication complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of FZD by ubiquitination";"Aggrephagy";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Cyclin D associated events in G1";"CLEC7A (Dectin-1) signaling";"Josephin domain DUBs";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Metalloprotease DUBs";"Oncogene Induced Senescence";"Peptide chain elongation";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Formation of a pool of free 40S subunits";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Processing of DNA double-strand break ends";"Regulation of TNFR1 signaling";"Hedgehog 'on' state";"Dual Incision in GG-NER";"Vpu mediated degradation of CD4";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downregulation of ERBB2:ERBB3 signaling";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NF-kB is activated and signals survival";"InlB-mediated entry of Listeria monocytogenes into host cell";"Translesion synthesis by POLI";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of TP53 Activity through Methylation";"IRAK1 recruits IKK complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Asymmetric localization of PCP proteins";"IKK complex recruitment mediated by RIP1";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"CDK-mediated phosphorylation and removal of Cdc6";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Ovarian tumor domain proteases";"Modulation by Mtb of host immune system";"Glycogen synthesis";"Regulation of PLK1 Activity at G2/M Transition";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"HDR through Homologous Recombination (HRR)";"Autodegradation of Cdh1 by Cdh1:APC/C";"NOD1/2 Signaling Pathway";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Amyloid fiber formation";"E3 ubiquitin ligases ubiquitinate target proteins";"Oxidative Stress Induced Senescence";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"ABC-family proteins mediated transport";"Formation of TC-NER Pre-Incision Complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Late endosomal microautophagy";"L13a-mediated translational silencing of Ceruloplasmin expression";"Dual incision in TC-NER";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"EGFR downregulation";"Downregulation of TGF-beta receptor signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Peroxisomal protein import";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Orc1 removal from chromatin";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Fanconi Anemia Pathway";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"UCH proteinases";"APC-Cdc20 mediated degradation of Nek2A";"Degradation of GLI1 by the proteasome";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Spry regulation of FGF signaling";"Assembly Of The HIV Virion";"Regulation of PTEN localization";"Defective CFTR causes cystic fibrosis";"TCF dependent signaling in response to WNT";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"p75NTR recruits signalling complexes";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of signaling by CBL";"NIK-->noncanonical NF-kB signaling";"Negative regulators of DDX58/IFIH1 signaling";"Chaperone Mediated Autophagy";"Activation of NF-kappaB in B cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"InlA-mediated entry of Listeria monocytogenes into host cells";"Formation of Incision Complex in GG-NER";"Pink/Parkin Mediated Mitophagy"
XP_011187641.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054088428.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054090503.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_054090940.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_028901012.1	2	Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Formation of apoptosome";"Regulation of the apoptosome activity"
XP_011192729.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_054083764.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011190532.2	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054081426.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054086159.1	9	Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928	"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis"
XP_011191674.2	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_011196055.1	14	MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-5981	"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III"
XP_054090362.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054083982.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_054083543.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_011194617.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_011186479.2	4	Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054082084.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_011189458.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054081954.1	4	KEGG: 00564+3.1.1.7;Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Glycerophospholipid metabolism";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_054081600.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054081682.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054084129.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011180631.1	4	Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656169	"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis"
XP_028898840.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054088265.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054086392.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_011192072.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011191795.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_054086279.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_011195975.2	5	KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-6317;MetaCyc: PWY-3821	"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification"
XP_054089650.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_011189752.2	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_011193575.1	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_028894511.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_054084851.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_011196001.2	12	Reactome: R-HSA-350054;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-9013695	"Notch-HLH transcription pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_054085994.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011193021.1	3	KEGG: 00600+1.14.19.17;MetaCyc: PWY-5129;Reactome: R-HSA-1660661	"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis"
XP_011190407.2	16	Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902	"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation"
XP_011185422.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_011180988.2	6	Reactome: R-HSA-977347;MetaCyc: PWY-8010;KEGG: 00270+2.6.1.52;KEGG: 00260+2.6.1.52;KEGG: 00750+2.6.1.52;KEGG: 00680+2.6.1.52	"Serine biosynthesis";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Vitamin B6 metabolism";"Methane metabolism"
XP_011196494.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_028897311.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_054081501.1	10	Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-200425;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Carnitine metabolism";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_011177786.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011194571.1	18	Reactome: R-HSA-69473;Reactome: R-HSA-6796648;Reactome: R-HSA-1221632;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-3371453;Reactome: R-HSA-6783310;Reactome: R-HSA-5693616;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic synapsis";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of HSF1-mediated heat shock response";"Fanconi Anemia Pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human immunodeficiency virus 1 infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_028900144.1	3	Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7	"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism"
XP_054092167.1	22	Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-389513	"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling"
XP_028898792.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011181012.2	7	Reactome: R-HSA-72187;Reactome: R-HSA-9033241;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-9010553	"mRNA 3'-end processing";"Peroxisomal protein import";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs"
XP_054082623.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_011187572.2	4	MetaCyc: PWY-5737;Reactome: R-HSA-70688;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2	"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism"
XP_011195011.2	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_011183412.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054082021.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_054084608.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011182902.2	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_011186024.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_011191270.2	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_011179579.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054089647.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_028893834.1	5	Reactome: R-HSA-8849471;Reactome: R-HSA-5218921;Reactome: R-HSA-5658442;Reactome: R-HSA-186763;Reactome: R-HSA-3928662	"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs";"Downstream signal transduction";"EPHB-mediated forward signaling"
XP_011191077.2	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_011194402.2	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_028900214.2	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_054082108.1	4	KEGG: 00790+2.8.1.12;MetaCyc: PWY-6823;Reactome: R-HSA-947581;MetaCyc: PWY-7887	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation"
XP_011178359.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011183725.1	7	KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.22	"Cysteine and methionine metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Arginine and proline metabolism"
XP_011190566.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011182881.1	29	MetaCyc: PWY-6333;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-6802;KEGG: 00260+1.1.1.1;MetaCyc: PWY-7013;MetaCyc: PWY-5082;MetaCyc: PWY-5076;MetaCyc: PWY-6342;MetaCyc: PWY-7396;MetaCyc: PWY-7111;MetaCyc: PWY-7118;MetaCyc: PWY-5057;MetaCyc: PWY-3162;MetaCyc: PWY-6313;KEGG: 00010+1.1.1.1;KEGG: 00592+1.1.1.1;KEGG: 00071+1.1.1.1;MetaCyc: PWY-5751;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5078;KEGG: 00980+1.1.1.1;MetaCyc: PWY-6587;KEGG: 00982+1.1.1.1;MetaCyc: PWY-5079;KEGG: 00350+1.1.1.1;MetaCyc: PWY-6871	"Acetaldehyde biosynthesis I";"Naphthalene degradation";"Pyruvate fermentation to ethanol I";"Chloroalkane and chloroalkene degradation";"Pyruvate fermentation to ethanol II";"Salidroside biosynthesis";"Glycine, serine and threonine metabolism";"(S)-propane-1,2-diol degradation";"L-methionine degradation III";"L-leucine degradation III";"Noradrenaline and adrenaline degradation";"Butanol and isobutanol biosynthesis (engineered)";"Pyruvate fermentation to isobutanol (engineered)";"Chitin degradation to ethanol";"L-valine degradation II";"L-tryptophan degradation V (side chain pathway)";"Serotonin degradation";"Glycolysis / Gluconeogenesis";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Phenylethanol biosynthesis";"Retinol metabolism";"L-isoleucine degradation II";"Metabolism of xenobiotics by cytochrome P450";"Pyruvate fermentation to ethanol III";"Drug metabolism - cytochrome P450";"L-phenylalanine degradation III";"Tyrosine metabolism";"3-methylbutanol biosynthesis (engineered)"
XP_011189180.1	14	MetaCyc: PWY-5057;KEGG: 00280+2.6.1.42;MetaCyc: PWY-7767;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5078;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5076;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-5108;Reactome: R-HSA-70895;MetaCyc: PWY-5101	"L-valine degradation II";"Valine, leucine and isoleucine degradation";"L-leucine degradation IV (Stickland reaction)";"Pantothenate and CoA biosynthesis";"L-isoleucine degradation II";"Glucosinolate biosynthesis";"L-leucine degradation III";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis III";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis V";"Branched-chain amino acid catabolism";"L-isoleucine biosynthesis II"
XP_054091834.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011186560.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_011184936.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_011182042.2	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_054084123.1	9	KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-6367;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-1855204	"Phosphatidylinositol signaling system";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol"
XP_028893873.2	7	Reactome: R-HSA-5693607;MetaCyc: PWY-7511;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-983168;Reactome: R-HSA-69473	"Processing of DNA double-strand break ends";"Protein ubiquitination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M DNA damage checkpoint"
XP_054087905.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011186473.2	4	Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054088570.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054090516.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_011178111.2	4	MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation"
XP_054083598.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_011195868.2	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_054081778.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119	"Sphingolipid metabolism";"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_011190139.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_011178297.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_011186596.2	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_011182579.1	12	Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-982772;Reactome: R-HSA-193692;Reactome: R-HSA-75893;Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-1251985;Reactome: R-HSA-5362798;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Growth hormone receptor signaling";"Regulated proteolysis of p75NTR";"TNF signaling";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Nuclear signaling by ERBB4";"Release of Hh-Np from the secreting cell";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_011192026.1	7	Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-212436;Reactome: R-HSA-2173796;Reactome: R-HSA-381340;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Generic Transcription Pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional regulation of white adipocyte differentiation";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_011195166.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_011188263.1	11	Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507	"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_054091918.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_054083729.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_028897013.1	11	KEGG: 04926+2.7.11.1;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human immunodeficiency virus 1 infection";"FOXO-mediated transcription of cell death genes";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_011191010.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_011192723.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054088073.1	2	Reactome: R-HSA-1299308;Reactome: R-HSA-5576886	"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential"
XP_028895461.1	22	Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-5358752;Reactome: R-HSA-141444;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-389513	"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling"
XP_054088860.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_011188145.1	7	MetaCyc: PWY-6124;KEGG: 00250+4.3.2.2;MetaCyc: PWY-6123;Reactome: R-HSA-73817;MetaCyc: PWY-7234;MetaCyc: PWY-7219;KEGG: 00230+4.3.2.2	"Inosine-5'-phosphate biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_011182869.1	5	Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949	"2-LTR circle formation";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA"
XP_011186751.1	13	Reactome: R-HSA-182218;Reactome: R-HSA-5140745;Reactome: R-HSA-8964038;Reactome: R-HSA-8866427;Reactome: R-HSA-437239;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-8856828;Reactome: R-HSA-167590	"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"LDL clearance";"VLDLR internalisation and degradation";"Recycling pathway of L1";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"Clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation"
XP_054081204.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_011194274.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_011187557.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_028901780.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_011182318.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054090752.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_011183993.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054090897.1	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_028901047.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_011187253.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054091470.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex"
XP_011190691.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_011194370.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011181759.1	13	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5627117;Reactome: R-HSA-4420097;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-416572;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"RHO GTPases Activate ROCKs";"VEGFA-VEGFR2 Pathway";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"EPHA-mediated growth cone collapse";"Sema4D induced cell migration and growth-cone collapse";"PI3K-Akt signaling pathway";"EPHB-mediated forward signaling";"Relaxin signaling pathway"
XP_054086095.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054087317.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_028901973.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_054091422.1	3	Reactome: R-HSA-6783984;KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"Glycine degradation";"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_054081665.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054082558.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_054088282.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011196148.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_011190438.2	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_028898033.2	13	Reactome: R-HSA-445989;Reactome: R-HSA-937042;Reactome: R-HSA-937072;Reactome: R-HSA-168638;Reactome: R-HSA-5607764;Reactome: R-HSA-975163;Reactome: R-HSA-9020702;Reactome: R-HSA-5357956;Reactome: R-HSA-9014325;Reactome: R-HSA-2871837;Reactome: R-HSA-450302;Reactome: R-HSA-9645460;Reactome: R-HSA-450321	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NOD1/2 Signaling Pathway";"CLEC7A (Dectin-1) signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"TNFR1-induced NFkappaB signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"FCERI mediated NF-kB activation";"activated TAK1 mediates p38 MAPK activation";"Alpha-protein kinase 1 signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_011188626.2	6	MetaCyc: PWY-922;MetaCyc: PWY-6174;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;Reactome: R-HSA-191273;KEGG: 00900+2.7.1.36	"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis"
XP_011191994.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_054085421.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-170670	"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Purine metabolism";"G alpha (z) signalling events";"G alpha (s) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway"
XP_011189552.1	8	Reactome: R-HSA-917977;Reactome: R-HSA-167590;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9636467;Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Nef Mediated CD4 Down-regulation";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Blockage of phagosome acidification";"Nef Mediated CD8 Down-regulation";"Ion channel transport";"Amino acids regulate mTORC1"
XP_011193775.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011179844.2	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_011194045.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054082097.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_011196846.2	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_011177240.2	2	Reactome: R-HSA-168138;Reactome: R-HSA-983231	"Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production"
XP_011186350.2	9	Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape"
XP_028898199.2	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_011178914.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054081574.1	3	Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-6804760	"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation"
XP_054090392.1	6	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-76005	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+"
XP_011189611.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_011194771.2	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_054088007.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_054082394.1	6	KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis";"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_011185879.2	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_054084956.1	8	Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-113501	"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_011181786.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054085795.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011182466.1	6	MetaCyc: PWY-7356;MetaCyc: PWY-6898;MetaCyc: PWY-6907;MetaCyc: PWY-6908;Reactome: R-HSA-196819;KEGG: 00730+2.7.6.2	"Thiamine salvage IV (yeast)";"Thiamine salvage III";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Vitamin B1 (thiamin) metabolism";"Thiamine metabolism"
XP_028893659.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-75035	"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_011187107.1	12	Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-2644606;Reactome: R-HSA-977225;Reactome: R-HSA-1251985	"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Amyloid fiber formation";"Nuclear signaling by ERBB4"
XP_011178288.1	9	KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-5789	"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_011184224.2	20	Reactome: R-HSA-5656121;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-110320	"Translesion synthesis by POLI";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH"
XP_028896370.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_028894124.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011190028.2	13	Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764	"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination"
XP_054085506.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011190683.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_028900609.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_011191943.2	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_028894785.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_028894562.2	8	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-917977;Reactome: R-HSA-77387;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Ion channel transport";"Photosynthesis";"ATP biosynthesis";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Oxidative phosphorylation";"ROS and RNS production in phagocytes"
XP_011189867.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011188114.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_054082205.1	5	Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
XP_011196310.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054090821.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054086636.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_011192913.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054087642.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_011179216.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054090186.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054083122.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011196214.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_028901471.1	7	Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-1221632;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519;Reactome: R-HSA-3108214	"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Meiotic synapsis";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins"
XP_054086207.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011196352.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_011189577.2	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_011192749.2	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_011176978.2	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_011190790.2	56	Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-382556	"Hedgehog ligand biogenesis";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport"
XP_028894443.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011186612.2	13	KEGG: 00240+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7227;KEGG: 00230+1.17.4.1	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism"
XP_011177272.1	2	Reactome: R-HSA-1268020;MetaCyc: PWY-7533	"Mitochondrial protein import";"Gliotoxin biosynthesis"
XP_011178918.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_054086710.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_054090692.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_054084481.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011186796.1	9	MetaCyc: PWY-6901;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-1042;KEGG: 00710+1.2.1.12	"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms"
XP_054087239.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_011194932.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_054091192.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_011187952.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011195062.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_028900536.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_054088805.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-418597	"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"G alpha (z) signalling events"
XP_028897752.2	4	Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_011187811.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-3247509	"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes"
XP_011190434.1	5	Reactome: R-HSA-8964539;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341;MetaCyc: PWY-6344	"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)"
XP_054092037.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_054091653.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_011192906.2	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_011185096.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport"
XP_028893653.1	22	Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-389513;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025	"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"RAF activation";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation"
XP_054083568.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_011182738.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011177091.1	7	MetaCyc: PWY-6351;Reactome: R-HSA-1483226;KEGG: 00564+2.7.8.11;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;MetaCyc: PWY-7625	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PI";"Glycerophospholipid metabolism";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis II (eukaryotes)"
XP_011190705.2	4	Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_011196468.2	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_054091763.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_054090685.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_011184588.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_054086135.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_054091544.1	19	Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-438066	"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Long-term potentiation";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_054088950.1	10	Reactome: R-HSA-1989781;KEGG: 00900+2.3.3.10;MetaCyc: PWY-922;MetaCyc: PWY-6174;KEGG: 00072+2.3.3.10;KEGG: 00280+2.3.3.10;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-7571;MetaCyc: PWY-7524	"PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Isoprene biosynthesis II (engineered)";"Ferrichrome A biosynthesis";"Mevalonate pathway III (archaea)"
XP_054081151.1	30	Reactome: R-HSA-6804758;Reactome: R-HSA-9614399;Reactome: R-HSA-389357;Reactome: R-HSA-211163;Reactome: R-HSA-1257604;Reactome: R-HSA-392451;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-8876198;Reactome: R-HSA-6804759;Reactome: R-HSA-69202;Reactome: R-HSA-199418;Reactome: R-HSA-5218920;Reactome: R-HSA-111447;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69656;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8948751;Reactome: R-HSA-1358803;Reactome: R-HSA-9634638;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198693;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-8941332;Reactome: R-HSA-389513;Reactome: R-HSA-198323	"Regulation of TP53 Activity through Acetylation";"Regulation of localization of FOXO transcription factors";"CD28 dependent PI3K/Akt signaling";"AKT-mediated inactivation of FOXO1A";"PIP3 activates AKT signaling";"G beta:gamma signalling through PI3Kgamma";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TP53 Activity through Association with Co-factors";"Cyclin E associated events during G1/S transition";"Negative regulation of the PI3K/AKT network";"VEGFR2 mediated vascular permeability";"Activation of BAD and translocation to mitochondria";"mTOR signaling pathway";"Cyclin A:Cdk2-associated events at S phase entry";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Regulation of PTEN stability and activity";"Downregulation of ERBB2:ERBB3 signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Relaxin signaling pathway";"TP53 Regulates Metabolic Genes";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the nucleus";"Thermogenesis";"Human papillomavirus infection";"RUNX2 regulates genes involved in cell migration";"CTLA4 inhibitory signaling";"AKT phosphorylates targets in the cytosol"
XP_054091066.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011185834.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011189019.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_011185284.2	8	Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-113501	"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Polymerase switching";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_011176477.1	22	Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-195253	"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex"
XP_054088444.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054088890.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011191700.3	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_011186347.2	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_011178834.1	2	Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29	"Threonine catabolism";"Glycine, serine and threonine metabolism"
XP_011181056.1	3	KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669;Reactome: R-HSA-1483213	"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE"
XP_011190661.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011187977.1	4	MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32	"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism"
XP_054089479.1	8	Reactome: R-HSA-5683826;MetaCyc: PWY-6611;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179	"Surfactant metabolism";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Neutrophil degranulation";"Purine metabolism";"Purine deoxyribonucleosides degradation I"
XP_054081829.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_011187388.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_054084542.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_054085333.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_011186505.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_054085748.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_011193432.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553	"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs"
XP_011189870.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054090683.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_011189063.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054088114.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_054083037.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_028898195.2	8	Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-212300	"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA"
XP_011186000.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_011184337.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_028896367.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054087107.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events"
XP_054086133.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_054090361.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_054086908.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054083981.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_011186926.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_028896202.1	6	Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-428930	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor"
XP_054090627.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism"
XP_011194253.2	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_011180351.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_011194916.2	3	Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400	"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER"
XP_011184776.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054083230.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054086099.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_011181755.1	13	KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-416572;Reactome: R-HSA-4420097;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5627117	"PI3K-Akt signaling pathway";"EPHB-mediated forward signaling";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"EPHA-mediated growth cone collapse";"Sema4D induced cell migration and growth-cone collapse";"VEGFA-VEGFR2 Pathway";"G alpha (12/13) signalling events";"Human papillomavirus infection";"Thermogenesis";"RHO GTPases Activate ROCKs"
XP_011182205.1	6	KEGG: 00190+7.1.2.2;Reactome: R-HSA-8949613;MetaCyc: PWY-7980;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210	"Oxidative phosphorylation";"Cristae formation";"ATP biosynthesis";"Mitochondrial protein import";"Photosynthesis";"Formation of ATP by chemiosmotic coupling"
XP_011187642.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_011197054.2	14	MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.42;Reactome: R-HSA-1483166;Reactome: R-HSA-75896;Reactome: R-HSA-9033241;MetaCyc: PWY-7587;MetaCyc: PWY-6453	"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"Plasmalogen biosynthesis";"Peroxisomal protein import";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis"
XP_054082734.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_054091127.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_054086822.1	13	KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"CS/DS degradation";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_028896064.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_054090389.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-76005	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+"
XP_011191353.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_011184198.2	8	MetaCyc: PWY-6372;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6580;MetaCyc: PWY-6664;KEGG: 00562+5.5.1.4;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;MetaCyc: PWY-4661	"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Streptomycin biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Di-myo-inositol phosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_054084852.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011180165.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_011189689.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_011180366.1	20	Reactome: R-HSA-5218920;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-6804757;Reactome: R-HSA-166208;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-389357;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"VEGFR2 mediated vascular permeability";"Macroautophagy";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"Amino acids regulate mTORC1";"Regulation of TP53 Degradation";"mTORC1-mediated signalling";"Thermogenesis";"PI3K-Akt signaling pathway";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"TP53 Regulates Metabolic Genes";"CD28 dependent PI3K/Akt signaling";"Human immunodeficiency virus 1 infection";"HSF1-dependent transactivation";"mTOR signalling";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_011191422.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_028897391.2	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_054084810.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_011193203.1	6	Reactome: R-HSA-1483166;MetaCyc: PWY-4261;Reactome: R-HSA-163560;MetaCyc: PWY-6952;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3	"Synthesis of PA";"Glycerol degradation I";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism"
XP_011189473.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054081502.1	10	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-200425;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-1445148	"TP53 Regulates Metabolic Genes";"Macroautophagy";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_028897312.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_011177733.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_011188522.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054086391.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_054091854.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_011180808.1	7	MetaCyc: PWY-3561;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;MetaCyc: PWY-7039	"Choline biosynthesis III";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Ether lipid metabolism";"Synthesis of PG";"Synthesis of PA";"Phosphatidate metabolism, as a signaling molecule"
XP_054081786.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011180632.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_028898527.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_011180547.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_011179409.2	5	MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism"
XP_054088803.1	56	Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-174178	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_054081324.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011194341.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_011188123.2	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_011184517.1	3	Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23	"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism"
XP_028899891.2	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_054088058.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_011191386.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_054089946.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_011196791.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_011190330.2	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_011188950.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_054081369.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_028896684.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054081818.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_054083489.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_011184038.2	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_028901755.2	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_011182041.2	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_054088809.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-418597	"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (s) signalling events";"G alpha (z) signalling events"
XP_054089920.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_011177196.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_011188717.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054091497.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_028896772.2	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_011180591.2	3	Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_054082507.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-164378	"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Purine metabolism";"G alpha (s) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation in glucagon signalling"
XP_011192969.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-389960	"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC"
XP_054089531.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011193893.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054082022.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_054088816.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_011192427.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828	"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis"
XP_011195012.2	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_054089475.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011190013.2	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_011186897.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_011192880.2	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_028896478.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_011179137.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054086258.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_011177160.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_011177457.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_011181306.2	15	Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-176034;Reactome: R-HSA-2173796;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246	"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript"
XP_011186710.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054086691.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_011187889.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054086139.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"HDACs deacetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_011190153.1	6	Reactome: R-HSA-3299685;Reactome: R-HSA-9033241;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6	"Detoxification of Reactive Oxygen Species";"Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism"
XP_011194286.2	5	MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2	"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism"
XP_054091189.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_011179775.2	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_011178112.2	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation"
XP_054085918.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_028897691.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054085793.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011178467.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;Reactome: R-HSA-197264;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21	"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_011197125.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_028899486.2	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054090689.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_011181868.2	6	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5693565;Reactome: R-HSA-8939211;Reactome: R-HSA-5675221	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ESR-mediated signaling";"Negative regulation of MAPK pathway"
XP_011189069.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054089587.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_011187380.1	10	Reactome: R-HSA-70263;KEGG: 00010+2.7.2.3;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-8004;KEGG: 00710+2.7.2.3;MetaCyc: PWY-7003;Reactome: R-HSA-70171	"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis"
XP_054084132.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5080	"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I"
XP_054083766.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011177118.1	8	Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825	"Formation of annular gap junctions";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis"
XP_054091862.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011190261.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054090963.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_011188152.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011189141.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_011193591.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_054089283.1	7	KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1483148;MetaCyc: PWY-7039;MetaCyc: PWY-3561;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485	"Ether lipid metabolism";"Synthesis of PA";"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis"
XP_011192389.1	83	Reactome: R-HSA-5654695;Reactome: R-HSA-9028731;Reactome: R-HSA-912526;Reactome: R-HSA-5654693;Reactome: R-HSA-8983432;Reactome: R-HSA-1839117;Reactome: R-HSA-2179392;Reactome: R-HSA-5654699;Reactome: R-HSA-9028335;Reactome: R-HSA-5654720;Reactome: R-HSA-1433559;Reactome: R-HSA-5654719;Reactome: R-HSA-391160;Reactome: R-HSA-8865999;Reactome: R-HSA-5654706;Reactome: R-HSA-1250347;Reactome: R-HSA-912631;Reactome: R-HSA-8853334;Reactome: R-HSA-9607240;Reactome: R-HSA-109704;Reactome: R-HSA-389359;Reactome: R-HSA-5655253;Reactome: R-HSA-512988;Reactome: R-HSA-5654704;Reactome: R-HSA-5673001;Reactome: R-HSA-9645135;Reactome: R-HSA-5654710;Reactome: R-HSA-5663213;Reactome: R-HSA-1963640;Reactome: R-HSA-9034864;Reactome: R-HSA-8875555;Reactome: R-HSA-5655291;Reactome: R-HSA-9027284;Reactome: R-HSA-180292;Reactome: R-HSA-375165;Reactome: R-HSA-210993;Reactome: R-HSA-9026519;Reactome: R-HSA-5654733;Reactome: R-HSA-1295596;Reactome: R-HSA-112412;Reactome: R-HSA-2730905;Reactome: R-HSA-983695;Reactome: R-HSA-8856825;Reactome: R-HSA-2029482;Reactome: R-HSA-2428933;Reactome: R-HSA-8856828;Reactome: R-HSA-388841;Reactome: R-HSA-74749;Reactome: R-HSA-5654732;Reactome: R-HSA-1257604;Reactome: R-HSA-2871796;Reactome: R-HSA-1250196;Reactome: R-HSA-2871809;Reactome: R-HSA-1433557;Reactome: R-HSA-8851907;Reactome: R-HSA-8853659;Reactome: R-HSA-167044;Reactome: R-HSA-1236382;Reactome: R-HSA-5654700;Reactome: R-HSA-186763;Reactome: R-HSA-6807004;Reactome: R-HSA-8851805;Reactome: R-HSA-5654689;Reactome: R-HSA-5655302;Reactome: R-HSA-6811558;Reactome: R-HSA-5654727;Reactome: R-HSA-182971;Reactome: R-HSA-180336;Reactome: R-HSA-5654726;Reactome: R-HSA-1963642;Reactome: R-HSA-9664565;Reactome: R-HSA-8875656;Reactome: R-HSA-5654712;Reactome: R-HSA-2219530;Reactome: R-HSA-5637810;Reactome: R-HSA-179812;Reactome: R-HSA-354194;Reactome: R-HSA-9634285;Reactome: R-HSA-8875360;Reactome: R-HSA-8853338;Reactome: R-HSA-74751;Reactome: R-HSA-5654688;Reactome: R-HSA-2424491	"PI-3K cascade:FGFR2";"Activated NTRK2 signals through FRS2 and FRS3";"Interleukin receptor SHC signaling";"FRS-mediated FGFR1 signaling";"Interleukin-15 signaling";"Signaling by cytosolic FGFR1 fusion mutants";"EGFR Transactivation by Gastrin";"SHC-mediated cascade:FGFR2";"Activated NTRK2 signals through PI3K";"PI-3K cascade:FGFR4";"Regulation of KIT signaling";"SHC-mediated cascade:FGFR4";"Signal regulatory protein family interactions";"MET activates PTPN11";"FRS-mediated FGFR3 signaling";"SHC1 events in ERBB4 signaling";"Regulation of signaling by CBL";"Signaling by FGFR3 fusions in cancer";"FLT3 Signaling";"PI3K Cascade";"CD28 dependent Vav1 pathway";"Signaling by FGFR2 in disease";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"SHC-mediated cascade:FGFR3";"RAF/MAP kinase cascade";"STAT5 Activation";"PI-3K cascade:FGFR3";"RHO GTPases Activate WASPs and WAVEs";"GRB2 events in ERBB2 signaling";"Activated NTRK3 signals through RAS";"MET activates RAP1 and RAC1";"Signaling by FGFR4 in disease";"Erythropoietin activates RAS";"GAB1 signalosome";"NCAM signaling for neurite out-growth";"Tie2 Signaling";"Activated NTRK2 signals through RAS";"Negative regulation of FGFR4 signaling";"Spry regulation of FGF signaling";"SOS-mediated signalling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"SHC-related events triggered by IGF1R";"Clathrin-mediated endocytosis";"Costimulation by the CD28 family";"Signal attenuation";"Negative regulation of FGFR3 signaling";"PIP3 activates AKT signaling";"FCERI mediated MAPK activation";"SHC1 events in ERBB2 signaling";"FCERI mediated Ca+2 mobilization";"Signaling by SCF-KIT";"MET activates PI3K/AKT signaling";"RET signaling";"Signalling to RAS";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"FRS-mediated FGFR2 signaling";"Downstream signal transduction";"Negative regulation of MET activity";"MET activates RAS signaling";"PI-3K cascade:FGFR1";"Signaling by FGFR1 in disease";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of FGFR2 signaling";"EGFR downregulation";"SHC1 events in EGFR signaling";"Negative regulation of FGFR1 signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"MET receptor recycling";"FRS-mediated FGFR4 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Constitutive Signaling by EGFRvIII";"GRB2 events in EGFR signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Constitutive Signaling by Overexpressed ERBB2";"InlB-mediated entry of Listeria monocytogenes into host cell";"Signaling by FGFR3 point mutants in cancer";"Insulin receptor signalling cascade";"SHC-mediated cascade:FGFR1";"DAP12 signaling"
XP_054081956.1	4	KEGG: 00564+3.1.1.7;Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Glycerophospholipid metabolism";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_054088472.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054082086.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_054086491.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011182494.1	3	MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315	"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol"
XP_054088958.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054081989.1	8	KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Activation of RAC1";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_011180953.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054084665.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054091134.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_054089046.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_011177293.2	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_054087374.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054089919.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054082727.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_054082243.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_011183884.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_011183685.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_011178667.1	8	Reactome: R-HSA-917977;MetaCyc: PWY-7980;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"ATP biosynthesis";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Oxidative phosphorylation";"Photosynthesis";"Ion channel transport";"Amino acids regulate mTORC1"
XP_054082547.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_054085571.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_028898017.1	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_011176660.1	25	Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-380270	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"RHO GTPases Activate Formins";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Recruitment of mitotic centrosome proteins and complexes"
XP_054085996.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_028894779.2	10	Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-200425;Reactome: R-HSA-2151209;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-163680;Reactome: R-HSA-6804756	"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Carnitine metabolism";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"TP53 Regulates Metabolic Genes";"Macroautophagy";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation"
XP_054085018.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_011178478.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_011190839.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156827	"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_011177784.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011176871.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_011181145.2	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_054083434.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011191850.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_011194183.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_011190256.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011179730.2	13	MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Hyaluronan uptake and degradation";"CS/DS degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Glycosaminoglycan degradation"
XP_011190529.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011188399.2	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_011184437.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_011181320.2	16	Reactome: R-HSA-1251985;Reactome: R-HSA-1963640;Reactome: R-HSA-9664565;Reactome: R-HSA-1250342;Reactome: R-HSA-1236394;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-1250196;Reactome: R-HSA-8847993;Reactome: R-HSA-1250347;Reactome: R-HSA-1227986;Reactome: R-HSA-6811558;Reactome: R-HSA-8863795;Reactome: R-HSA-5673001;Reactome: R-HSA-6785631;Reactome: R-HSA-1963642	"Nuclear signaling by ERBB4";"GRB2 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB4 signaling";"Signaling by ERBB4";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"SHC1 events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"SHC1 events in ERBB4 signaling";"Signaling by ERBB2";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Downregulation of ERBB2 signaling";"RAF/MAP kinase cascade";"ERBB2 Regulates Cell Motility";"PI3K events in ERBB2 signaling"
XP_011177244.1	5	Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695	"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation"
XP_011181567.2	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_011187096.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_011179181.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011185621.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_011193351.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"HCMV Late Events"
XP_011184535.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011179857.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_011177054.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-186763;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921;Reactome: R-HSA-8849471	"EPHB-mediated forward signaling";"Downstream signal transduction";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"
XP_011182163.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_011189071.1	11	MetaCyc: PWY-6607;MetaCyc: PWY-6608;MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-7821;MetaCyc: PWY-5381;KEGG: 00240+3.1.3.5;KEGG: 00230+3.1.3.5;MetaCyc: PWY-7185;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6606	"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Tunicamycin biosynthesis";"Pyridine nucleotide cycling (plants)";"Pyrimidine metabolism";"Purine metabolism";"UTP and CTP dephosphorylation I";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation II"
XP_028900216.2	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_054086121.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_054087147.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054087875.1	1	KEGG: 00906+1.23.5.1	"Carotenoid biosynthesis"
XP_011182785.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054091836.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_054084085.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_028899763.2	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_011190919.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_011177482.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1538133	"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"G0 and Early G1"
XP_011194713.2	4	MetaCyc: PWY-7887;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-6823	"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_028896923.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels"
XP_054091455.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_011192689.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_054089411.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_011189924.2	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_054090037.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_054085274.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_054082666.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_011179609.2	17	Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-69166;Reactome: R-HSA-174417;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-174414;Reactome: R-HSA-174437;Reactome: R-HSA-174411	"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Removal of the Flap Intermediate";"Telomere C-strand (Lagging Strand) Synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"Polymerase switching on the C-strand of the telomere"
XP_011186900.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-174411	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere"
XP_011194858.2	3	Reactome: R-HSA-204005;Reactome: R-HSA-162658;Reactome: R-HSA-6807878	"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport"
XP_011186026.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_011187602.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_011193808.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_028901263.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_054081206.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_054084092.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054089913.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054081637.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054082053.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_011196325.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_054082298.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_054090427.1	9	MetaCyc: PWY-6983;MetaCyc: PWY-5663;MetaCyc: PWY-5664;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-6147;MetaCyc: PWY-7852;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6703	"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Folate biosynthesis";"Preq0 biosynthesis"
XP_054090514.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_011186594.2	3	Reactome: R-HSA-4724289;KEGG: 00510+2.4.1.267;Reactome: R-HSA-446193	"Defective ALG6 causes ALG6-CDG (CDG-1c)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_011180507.1	7	Reactome: R-HSA-77348;Reactome: R-HSA-77346;KEGG: 00071+1.3.8.7;KEGG: 00280+1.3.8.7;MetaCyc: PWY-7094;Reactome: R-HSA-1989781;Reactome: R-HSA-77288	"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Fatty acid degradation";"Valine, leucine and isoleucine degradation";"Fatty acid salvage";"PPARA activates gene expression";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids"
XP_054090969.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_011184089.1	56	Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-75815	"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D"
XP_011181588.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_011176527.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011195164.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_054088208.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011195123.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_028896339.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054084151.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011181521.2	5	KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22	"Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism"
XP_011186853.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_028894349.2	6	Reactome: R-HSA-6803204;Reactome: R-HSA-139915;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6803211;Reactome: R-HSA-6804759	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors"
XP_011177604.2	18	MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;MetaCyc: PWY-7416	"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_028901927.2	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_011181776.2	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_011183473.2	16	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-192823	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation"
XP_054084669.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-189085	"Stimuli-sensing channels";"Digestion of dietary carbohydrate"
XP_054082055.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011177493.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054081985.1	8	Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Activation of RAC1";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_011193449.2	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
XP_011177576.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_054092081.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_011196084.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
XP_054089915.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054086549.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054091951.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport"
XP_011190197.1	5	MetaCyc: PWY-5074;KEGG: 00280+4.1.3.4;KEGG: 00650+4.1.3.4;KEGG: 00072+4.1.3.4;KEGG: 00281+4.1.3.4	"Mevalonate degradation";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Synthesis and degradation of ketone bodies";"Geraniol degradation"
XP_011178239.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054086354.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_054082169.1	4	Reactome: R-HSA-937039;Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-9020702	"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"Interleukin-1 signaling"
XP_011191909.2	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_011178435.1	16	Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-176408	"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase"
XP_028898364.2	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054086250.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_054089679.1	14	Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-380270;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Recruitment of mitotic centrosome proteins and complexes";"Separation of Sister Chromatids"
XP_011183751.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_054084437.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011195962.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_011185158.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054084220.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011182366.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_011182922.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_011185861.1	7	Reactome: R-HSA-606279;Reactome: R-HSA-5689880;Reactome: R-HSA-171319;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-5696394;Reactome: R-HSA-201722	"Deposition of new CENPA-containing nucleosomes at the centromere";"Ub-specific processing proteases";"Telomere Extension By Telomerase";"UCH proteinases";"HATs acetylate histones";"DNA Damage Recognition in GG-NER";"Formation of the beta-catenin:TCF transactivating complex"
XP_054082494.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054082840.1	3	Reactome: R-HSA-418457;Reactome: R-HSA-392517;Reactome: R-HSA-4086398	"cGMP effects";"Rap1 signalling";"Ca2+ pathway"
XP_054084324.1	5	MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6906;MetaCyc: PWY-6855	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin derivatives degradation";"Chitin degradation I (archaea)"
XP_054081992.1	7	Reactome: R-HSA-212676;Reactome: R-HSA-3000170;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-6794361;Reactome: R-HSA-373753	"Dopamine Neurotransmitter Release Cycle";"Syndecan interactions";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Neurexins and neuroligins";"Nephrin family interactions"
XP_011178960.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011189020.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_011178571.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_028899765.2	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_054087060.1	30	Reactome: R-HSA-2122947;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-5684264;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-2565942;Reactome: R-HSA-180534;Reactome: R-HSA-917937;Reactome: R-HSA-5610785;Reactome: R-HSA-2644606;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-1170546;Reactome: R-HSA-9020702;Reactome: R-HSA-2894862;Reactome: R-HSA-2644607;Reactome: R-HSA-5607761;Reactome: R-HSA-400253;Reactome: R-HSA-69231;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050	"NOTCH1 Intracellular Domain Regulates Transcription";"CLEC7A (Dectin-1) signaling";"Neddylation";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PLK1 Activity at G2/M Transition";"Vpu mediated degradation of CD4";"Iron uptake and transport";"GLI3 is processed to GLI3R by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Prolactin receptor signaling";"Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Circadian Clock";"Cyclin D associated events in G1";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_011182783.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_054088404.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_011192392.1	83	Reactome: R-HSA-5654733;Reactome: R-HSA-1295596;Reactome: R-HSA-112412;Reactome: R-HSA-180292;Reactome: R-HSA-9027284;Reactome: R-HSA-9026519;Reactome: R-HSA-375165;Reactome: R-HSA-210993;Reactome: R-HSA-5655291;Reactome: R-HSA-9034864;Reactome: R-HSA-1963640;Reactome: R-HSA-8875555;Reactome: R-HSA-5654710;Reactome: R-HSA-9645135;Reactome: R-HSA-5663213;Reactome: R-HSA-5673001;Reactome: R-HSA-5654704;Reactome: R-HSA-512988;Reactome: R-HSA-5655253;Reactome: R-HSA-8853334;Reactome: R-HSA-1250347;Reactome: R-HSA-912631;Reactome: R-HSA-9607240;Reactome: R-HSA-389359;Reactome: R-HSA-109704;Reactome: R-HSA-5654706;Reactome: R-HSA-5654719;Reactome: R-HSA-1433559;Reactome: R-HSA-8865999;Reactome: R-HSA-391160;Reactome: R-HSA-9028335;Reactome: R-HSA-5654720;Reactome: R-HSA-5654699;Reactome: R-HSA-1839117;Reactome: R-HSA-2179392;Reactome: R-HSA-8983432;Reactome: R-HSA-9028731;Reactome: R-HSA-5654695;Reactome: R-HSA-5654693;Reactome: R-HSA-912526;Reactome: R-HSA-74751;Reactome: R-HSA-5654688;Reactome: R-HSA-2424491;Reactome: R-HSA-8853338;Reactome: R-HSA-354194;Reactome: R-HSA-179812;Reactome: R-HSA-9634285;Reactome: R-HSA-8875360;Reactome: R-HSA-2219530;Reactome: R-HSA-5637810;Reactome: R-HSA-9664565;Reactome: R-HSA-8875656;Reactome: R-HSA-5654712;Reactome: R-HSA-1963642;Reactome: R-HSA-182971;Reactome: R-HSA-5654726;Reactome: R-HSA-180336;Reactome: R-HSA-5654689;Reactome: R-HSA-8851805;Reactome: R-HSA-6807004;Reactome: R-HSA-5655302;Reactome: R-HSA-6811558;Reactome: R-HSA-5654727;Reactome: R-HSA-1236382;Reactome: R-HSA-186763;Reactome: R-HSA-5654700;Reactome: R-HSA-8853659;Reactome: R-HSA-167044;Reactome: R-HSA-1433557;Reactome: R-HSA-1250196;Reactome: R-HSA-2871809;Reactome: R-HSA-8851907;Reactome: R-HSA-5654732;Reactome: R-HSA-1257604;Reactome: R-HSA-2871796;Reactome: R-HSA-74749;Reactome: R-HSA-8856828;Reactome: R-HSA-388841;Reactome: R-HSA-2428933;Reactome: R-HSA-2029482;Reactome: R-HSA-8856825;Reactome: R-HSA-983695;Reactome: R-HSA-2730905	"Negative regulation of FGFR4 signaling";"Spry regulation of FGF signaling";"SOS-mediated signalling";"GAB1 signalosome";"Erythropoietin activates RAS";"Activated NTRK2 signals through RAS";"NCAM signaling for neurite out-growth";"Tie2 Signaling";"Signaling by FGFR4 in disease";"Activated NTRK3 signals through RAS";"GRB2 events in ERBB2 signaling";"MET activates RAP1 and RAC1";"PI-3K cascade:FGFR3";"STAT5 Activation";"RHO GTPases Activate WASPs and WAVEs";"RAF/MAP kinase cascade";"SHC-mediated cascade:FGFR3";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Signaling by FGFR2 in disease";"Signaling by FGFR3 fusions in cancer";"SHC1 events in ERBB4 signaling";"Regulation of signaling by CBL";"FLT3 Signaling";"CD28 dependent Vav1 pathway";"PI3K Cascade";"FRS-mediated FGFR3 signaling";"SHC-mediated cascade:FGFR4";"Regulation of KIT signaling";"MET activates PTPN11";"Signal regulatory protein family interactions";"Activated NTRK2 signals through PI3K";"PI-3K cascade:FGFR4";"SHC-mediated cascade:FGFR2";"Signaling by cytosolic FGFR1 fusion mutants";"EGFR Transactivation by Gastrin";"Interleukin-15 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"PI-3K cascade:FGFR2";"FRS-mediated FGFR1 signaling";"Interleukin receptor SHC signaling";"Insulin receptor signalling cascade";"SHC-mediated cascade:FGFR1";"DAP12 signaling";"Signaling by FGFR3 point mutants in cancer";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"GRB2 events in EGFR signaling";"Constitutive Signaling by Overexpressed ERBB2";"InlB-mediated entry of Listeria monocytogenes into host cell";"Constitutive Signaling by Aberrant PI3K in Cancer";"Constitutive Signaling by EGFRvIII";"Signaling by ERBB2 KD Mutants";"MET receptor recycling";"FRS-mediated FGFR4 signaling";"PI3K events in ERBB2 signaling";"EGFR downregulation";"Negative regulation of FGFR1 signaling";"SHC1 events in EGFR signaling";"PI-3K cascade:FGFR1";"MET activates RAS signaling";"Negative regulation of MET activity";"Signaling by FGFR1 in disease";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of FGFR2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Downstream signal transduction";"FRS-mediated FGFR2 signaling";"RET signaling";"Signalling to RAS";"Signaling by SCF-KIT";"SHC1 events in ERBB2 signaling";"FCERI mediated Ca+2 mobilization";"MET activates PI3K/AKT signaling";"Negative regulation of FGFR3 signaling";"PIP3 activates AKT signaling";"FCERI mediated MAPK activation";"Signal attenuation";"Clathrin-mediated endocytosis";"Costimulation by the CD28 family";"SHC-related events triggered by IGF1R";"Regulation of actin dynamics for phagocytic cup formation";"Cargo recognition for clathrin-mediated endocytosis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Role of LAT2/NTAL/LAB on calcium mobilization"
XP_054084246.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_011187678.2	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_011181149.2	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_028899601.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011197050.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_011189122.2	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_011185571.1	10	Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-3214847	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HATs acetylate histones"
XP_011181989.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_011185704.2	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_054088050.1	12	Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;MetaCyc: PWY-7221	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Long-term potentiation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis"
XP_054087524.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism"
XP_054084027.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_054089802.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054087417.1	29	Reactome: R-HSA-69473;Reactome: R-HSA-6796648;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6803204;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693568;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693579;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-6804760;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693565;Reactome: R-HSA-912446;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69541;Reactome: R-HSA-349425;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-6804757;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-3371453;Reactome: R-HSA-6803207	"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of DNA Repair Genes";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Human papillomavirus infection";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Thermogenesis";"Resolution of D-loop Structures through Holliday Junction Intermediates";"PI3K-Akt signaling pathway";"Homologous DNA Pairing and Strand Exchange";"Relaxin signaling pathway";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Methylation";"Human immunodeficiency virus 1 infection";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"Human cytomegalovirus infection";"mTOR signaling pathway";"Stabilization of p53";"Autodegradation of the E3 ubiquitin ligase COP1";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Regulation of TP53 Degradation";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of HSF1-mediated heat shock response";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_054082181.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_028894775.2	10	Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-200425	"Activation of AMPK downstream of NMDARs";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism"
XP_011184092.1	56	Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-5362768	"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_054082857.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_011182298.1	4	MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614	"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage"
XP_011192273.1	4	MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621	"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Pyrimidine catabolism"
XP_054087914.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_054091459.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex"
XP_054081831.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_011189798.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_054088559.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_011195936.1	7	MetaCyc: PWY-7158;MetaCyc: PWY-6134;KEGG: 00360+1.14.16.1;Reactome: R-HSA-2160456;KEGG: 00400+1.14.16.1;KEGG: 00790+1.14.16.1;Reactome: R-HSA-8964208	"L-phenylalanine degradation V";"L-tyrosine biosynthesis IV";"Phenylalanine metabolism";"Phenylketonuria";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Folate biosynthesis";"Phenylalanine metabolism"
XP_011177832.1	9	Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-5674135;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-6798695	"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"MAP2K and MAPK activation";"Amino acids regulate mTORC1";"mTOR signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Neutrophil degranulation"
XP_011191401.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_011184151.1	6	MetaCyc: PWY-6854;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-9615017;Reactome: R-HSA-8862803;Reactome: R-HSA-8950505	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_011176988.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054086436.1	3	Reactome: R-HSA-3214815;Reactome: R-HSA-427413;Reactome: R-HSA-390522	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression";"Striated Muscle Contraction"
XP_011196664.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_011194066.1	5	Reactome: R-HSA-392154;Reactome: R-HSA-1222556;KEGG: 00330+1.14.13.39;MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39	"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes";"Arginine and proline metabolism";"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis"
XP_011179666.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_011197131.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054088702.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011189839.2	27	Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-3371453	"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"snRNP Assembly";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response"
XP_054088047.1	12	Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308;Reactome: R-HSA-8849932	"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules"
XP_011183389.1	56	Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257	"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Separation of Sister Chromatids";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN"
XP_054083821.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054085064.1	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6317	"Galactose metabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)"
XP_054082785.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_028894171.2	5	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_054086040.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_011186886.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_011187674.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054091622.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_011179651.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_054085726.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_011176423.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011176464.2	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_011179249.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-674695;Reactome: R-HSA-5632684;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654	"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Pre-transcription Events";"Hedgehog 'on' state";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_054081215.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054091737.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_054090965.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_011187565.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_054086543.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054084663.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054085367.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_054084624.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_011176487.2	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_028897040.2	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_011181481.1	6	Reactome: R-HSA-1989781;Reactome: R-HSA-3214815;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-9609690;Reactome: R-HSA-9022537	"PPARA activates gene expression";"HDACs deacetylate histones";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HCMV Early Events";"Loss of MECP2 binding ability to the NCoR/SMRT complex"
XP_054084061.1	13	MetaCyc: PWY-7254;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-561;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2;Reactome: R-HSA-71403;KEGG: 00720+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-6728	"TCA cycle VII (acetate-producers)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle"
XP_011179550.1	10	Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00600+3.2.1.23	"HS-GAG degradation";"Galactose metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Sphingolipid metabolism"
XP_011191068.2	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_011193218.2	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5689877;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"Josephin domain DUBs";"DNA Damage Recognition in GG-NER"
XP_054081657.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_011180296.2	5	Reactome: R-HSA-4755579;KEGG: 00510+1.3.1.94;MetaCyc: PWY-6129;Reactome: R-HSA-446199;Reactome: R-HSA-193048	"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Androgen biosynthesis"
XP_028893571.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054085134.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_011179195.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011185322.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_011196394.1	6	KEGG: 00710+5.1.3.1;MetaCyc: PWY-1861;KEGG: 00040+5.1.3.1;Reactome: R-HSA-71336;MetaCyc: PWY-5723;KEGG: 00030+5.1.3.1	"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Rubisco shunt";"Pentose phosphate pathway"
XP_054084699.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_028896185.1	5	Reactome: R-HSA-1834949;Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571	"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)"
XP_028899782.2	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_011187161.2	6	KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;MetaCyc: PWY-622	"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis"
XP_028899700.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054089188.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_011187276.2	3	Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial protein import"
XP_011197056.2	14	KEGG: 00564+2.3.1.42;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-6453;Reactome: R-HSA-75896;MetaCyc: PWY-7587;Reactome: R-HSA-9033241;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-7782	"Glycerophospholipid metabolism";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Peroxisomal protein import";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Plasmalogen biosynthesis"
XP_054082736.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_028893670.1	13	KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802946	"PI3K-Akt signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Relaxin signaling pathway";"Signaling by high-kinase activity BRAF mutants";"Human papillomavirus infection";"Human cytomegalovirus infection";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Signaling by moderate kinase activity BRAF mutants"
XP_011189026.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054091861.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011190167.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_011196558.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_011183178.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054082530.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054088471.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054086878.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_011184208.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054091670.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_054091025.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_028899031.2	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_011193592.2	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_011186924.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9	"Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis"
XP_054091856.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_054088535.1	4	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_028895751.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_011190993.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054083752.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_011188319.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_011192731.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_054092048.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_054081125.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_011194528.1	8	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Signaling by Hippo";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_054081326.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054081962.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_054085697.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_028896297.2	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_011192180.2	19	Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00720+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-1622;Reactome: R-HSA-71403;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-8086;MetaCyc: PWY-6969;KEGG: 00630+1.1.1.37;KEGG: 00680+1.1.1.37	"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation in photosynthetic organisms";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Formaldehyde assimilation I (serine pathway)";"Citric acid cycle (TCA cycle)";"Cysteine and methionine metabolism";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism"
XP_011188166.2	31	MetaCyc: PWY-5367;Reactome: R-HSA-2426168;MetaCyc: PWY-7388;MetaCyc: PWY-6519;MetaCyc: PWY-4381;MetaCyc: PWY-5147;MetaCyc: PWY-5989;MetaCyc: PWYG-321;MetaCyc: PWY-6113;MetaCyc: PWY-7858;MetaCyc: PWY-7723;MetaCyc: PWY-5966-1;MetaCyc: PWY-5971;MetaCyc: PWY-7664;MetaCyc: PWY-6799;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-199220;MetaCyc: PWY-6282;Reactome: R-HSA-163765;MetaCyc: PWY-8049;MetaCyc: PWY-8012;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7746;MetaCyc: PWY-8047;MetaCyc: PWY-7663;Reactome: R-HSA-75105;MetaCyc: PWY-5994;MetaCyc: PWY-5973;Reactome: R-HSA-9029558;MetaCyc: PWY-5366;MetaCyc: PWY-5142	"Petroselinate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis I (plants)";"Stearate biosynthesis II (bacteria and plants)";"";"Superpathway of mycolate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Bacterial bioluminescence";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Biotin metabolism";"Vitamin B5 (pantothenate) metabolism";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"ChREBP activates metabolic gene expression";"Pederin biosynthesis";"Mupirocin biosynthesis";"Fatty acid biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Bryostatin biosynthesis";"Gondoate biosynthesis (anaerobic)";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Cis-vaccenate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Acyl-[acyl-carrier protein] thioesterase pathway"
XP_028894329.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_011195263.2	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_054087297.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_054083516.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011180323.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054081767.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_011196416.2	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_011184695.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_028900865.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011184440.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257	"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion"
XP_054091018.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_054090057.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_011194335.1	6	Reactome: R-HSA-8863795;Reactome: R-HSA-2173788;Reactome: R-HSA-8939902;MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-8948751	"Downregulation of ERBB2 signaling";"Downregulation of TGF-beta receptor signaling";"Regulation of RUNX2 expression and activity";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity"
XP_011187009.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_054087593.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_011191910.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_011178737.1	2	Reactome: R-HSA-191859;Reactome: R-HSA-6807505	"snRNP Assembly";"RNA polymerase II transcribes snRNA genes"
XP_054086833.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011191087.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054089412.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054087130.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_011186037.1	2	Reactome: R-HSA-429958;Reactome: R-HSA-390471	"mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis"
XP_054087548.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_011187601.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_054088814.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_011178622.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_011183908.1	4	MetaCyc: PWY-5912;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581	"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"Methylation"
XP_054090900.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_011184204.1	9	KEGG: 00720+6.4.1.1;MetaCyc: PWY-8086;Reactome: R-HSA-3371599;Reactome: R-HSA-70263;KEGG: 00620+6.4.1.1;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-6146;Reactome: R-HSA-196780	"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Biotin transport and metabolism"
XP_011189170.2	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_011191546.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_028902100.2	8	Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-5610787	"DARPP-32 events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state"
XP_054086122.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_054091827.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_011194918.1	14	MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453	"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Plasmalogen biosynthesis";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Stigma estolide biosynthesis"
XP_028896686.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_011179791.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011191064.1	7	Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-390450	"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC"
XP_028894410.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_028894084.1	6	Reactome: R-HSA-194840;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855204	"Rho GTPase cycle";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol"
XP_028899968.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_011195215.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_028901851.2	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_054081357.1	3	Reactome: R-HSA-189085;Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"Digestion of dietary carbohydrate";"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_011187183.2	13	Reactome: R-HSA-937042;Reactome: R-HSA-937072;Reactome: R-HSA-168638;Reactome: R-HSA-975163;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-445989;Reactome: R-HSA-2871837;Reactome: R-HSA-9645460;Reactome: R-HSA-450302;Reactome: R-HSA-450321;Reactome: R-HSA-5357956;Reactome: R-HSA-9014325	"IRAK2 mediated activation of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway";"activated TAK1 mediates p38 MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TNFR1-induced NFkappaB signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex"
XP_054083636.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_011190886.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054090040.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_011188420.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011189057.2	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-2980766	"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown"
XP_011180819.2	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_054081640.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_011180088.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054082511.1	13	Reactome: R-HSA-6802948;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674135;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802952	"Signaling by high-kinase activity BRAF mutants";"Relaxin signaling pathway";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"PI3K-Akt signaling pathway";"Thermogenesis";"Signaling by moderate kinase activity BRAF mutants";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"MAP2K and MAPK activation";"Human papillomavirus infection";"Signaling by BRAF and RAF fusions"
XP_011184196.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_011192458.2	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_011176840.2	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011193199.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_011180623.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011177206.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054087715.1	6	KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381;Reactome: R-HSA-196807;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653;MetaCyc: PWY-7761	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)"
XP_011194380.2	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_054084152.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054090995.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_011184898.2	4	Reactome: R-HSA-983189;Reactome: R-HSA-68884;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_054082193.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_011188533.1	33	Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-141444;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-159231	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"tRNA processing in the nucleus";"snRNP Assembly";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_028900260.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011187595.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-191859;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201	"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"snRNP Assembly";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_011189117.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-171319	"HATs acetylate histones";"Telomere Extension By Telomerase"
XP_011177927.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_011188823.2	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_028896715.2	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054081626.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_054084693.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_011196882.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054088103.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-418597	"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (s) signalling events";"G alpha (z) signalling events"
XP_011188619.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054084091.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_011193033.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_011184393.1	9	Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-1042;KEGG: 00710+1.2.1.12;MetaCyc: PWY-6901;MetaCyc: PWY-5484;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70263	"Glycolysis";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis"
XP_011182214.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_054091478.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex"
XP_011188973.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054082396.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_011183752.1	7	KEGG: 00230+3.6.1.15;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-6545;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7185;MetaCyc: PWY-7184	"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Thiamine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_054082195.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011177346.2	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
YP_004891176.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054087713.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_011190462.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054084954.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_011180625.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_054088868.1	11	Reactome: R-HSA-202733;Reactome: R-HSA-3560783;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-3000170;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475	"Cell surface interactions at the vascular wall";"Defective B4GALT7 causes EDS, progeroid type";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Syndecan interactions";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054084695.1	5	MetaCyc: PWY-7204;KEGG: 00750+2.7.1.35;Reactome: R-HSA-6798695;Reactome: R-HSA-964975;MetaCyc: PWY-7282	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"Neutrophil degranulation";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_011188624.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011195776.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_028900140.2	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_011188825.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054081770.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_054092082.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_028893910.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_054088578.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011190598.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054088105.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_011189121.2	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
XP_054086489.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_028899602.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011186568.1	56	Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-382556	"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"ABC-family proteins mediated transport"
XP_011184648.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054086634.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054082100.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054082837.1	3	Reactome: R-HSA-418457;Reactome: R-HSA-4086398;Reactome: R-HSA-392517	"cGMP effects";"Ca2+ pathway";"Rap1 signalling"
XP_028893885.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_028895330.2	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_011197011.1	13	Reactome: R-HSA-6802955;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802948;Reactome: R-HSA-9649948;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Signaling by high-kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Thermogenesis";"mTOR signaling pathway"
XP_011184226.2	5	Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-198323;Reactome: R-HSA-3371571;Reactome: R-HSA-5674400	"mTORC1-mediated signalling";"mTOR signalling";"AKT phosphorylates targets in the cytosol";"HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_011191278.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011191025.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054091667.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_054086963.1	7	KEGG: 00230+1.1.1.205;MetaCyc: PWY-7221;MetaCyc: PWY-6596;Reactome: R-HSA-6798695;MetaCyc: PWY-5695;KEGG: 00983+1.1.1.205;Reactome: R-HSA-73817	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine nucleotides degradation I";"Neutrophil degranulation";"Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis"
XP_011184047.2	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_054088539.1	4	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_011178572.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_011190170.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_054083505.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_011188315.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_054088701.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011177228.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_028900534.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828	"TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis"
XP_011188628.1	27	Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-159231	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_011196203.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_054088533.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_011178397.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_011181803.2	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"Kinesins"
XP_028894157.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054086969.1	4	Reactome: R-HSA-8849175;MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493	"Threonine catabolism";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2"
XP_011187769.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011181640.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin"
XP_011193360.2	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_011185094.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011196022.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011192904.2	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_011195469.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054084395.1	3	Reactome: R-HSA-525793;Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Myogenesis";"Ligand-receptor interactions";"Activation of SMO"
XP_011182511.1	5	MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560	"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II"
XP_054081123.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_028896854.1	7	Reactome: R-HSA-6794361;Reactome: R-HSA-373753;Reactome: R-HSA-212676;Reactome: R-HSA-3000170;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8	"Neurexins and neuroligins";"Nephrin family interactions";"Dopamine Neurotransmitter Release Cycle";"Syndecan interactions";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism"
XP_054088619.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_011184012.2	56	Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-1169091	"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells"
XP_054082791.1	4	MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32	"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism"
XP_011180707.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054088030.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_011176547.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011177741.2	5	Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381	"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_028898203.2	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_054087595.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_011195637.1	3	Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-8939243	"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_011194333.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054081832.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_011192566.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011177588.1	3	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)"
XP_054081608.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_011184693.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_054087706.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_054088446.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_028899162.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011177419.2	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054089768.1	34	Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-9639288;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-3301854;Reactome: R-HSA-159231	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Transcriptional regulation by small RNAs";"snRNP Assembly";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amino acids regulate mTORC1";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_054087222.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011181054.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-1632852	"Ub-specific processing proteases";"Macroautophagy"
XP_011186020.2	4	Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320	"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation"
XP_054087003.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_011190764.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6811438	"RAB geranylgeranylation";"Intra-Golgi traffic"
XP_011179193.1	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_011187548.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_011178540.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054085737.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_028895888.2	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_054088313.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_054090948.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_011180318.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649	"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation"
XP_028895630.2	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_054091202.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_011182967.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_028899834.2	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_054088420.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054083048.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_011190040.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins"
XP_011189307.1	6	MetaCyc: PWY-7433;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290	"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_054091546.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9649948	"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants"
XP_011190787.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895	"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis"
XP_011186227.2	5	Reactome: R-HSA-380994;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693	"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_028898432.2	13	MetaCyc: PWY-7909;MetaCyc: PWY-3841;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2161;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-6613;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9	"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Folate polyglutamylation";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate"
XP_054081499.1	10	Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-2151209;Reactome: R-HSA-200425;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_028893830.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011185286.2	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_011185836.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011194010.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_011179610.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011176499.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054091019.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054081390.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054087543.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_011189066.1	4	Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-8953750	"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6"
XP_011190003.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_011194289.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_011180814.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_011187859.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054090807.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_011194485.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_011188815.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_028894328.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_028896764.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011187948.1	8	Reactome: R-HSA-5659996;KEGG: 00051+5.3.1.6;KEGG: 00710+5.3.1.6;KEGG: 00030+5.3.1.6;MetaCyc: PWY-5723;Reactome: R-HSA-71336;MetaCyc: PWY-1861;Reactome: R-HSA-6791461	"RPIA deficiency: failed conversion of R5P to RU5P";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Rubisco shunt";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"RPIA deficiency: failed conversion of RU5P to R5P"
XP_011184076.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054082671.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_011191275.2	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_054086581.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_011190582.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Ion channel transport"
XP_054088754.1	23	Reactome: R-HSA-400042;Reactome: R-HSA-420092;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-418217;Reactome: R-HSA-202040;Reactome: R-HSA-418597;Reactome: R-HSA-6814122;Reactome: R-HSA-381676;Reactome: R-HSA-500657;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-9009391;Reactome: R-HSA-428930;Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-418555;Reactome: R-HSA-416482;Reactome: R-HSA-456926;Reactome: R-HSA-8964315	"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PLC beta";"G-protein activation";"G alpha (z) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Presynaptic function of Kainate receptors";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"Extra-nuclear estrogen signaling";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"G alpha (s) signalling events";"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through BTK"
XP_011190943.1	4	Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-982772	"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Signaling by Leptin";"Growth hormone receptor signaling"
XP_054087787.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_011178180.1	17	Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012	"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_011180979.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_028899456.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054086442.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054091475.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling"
XP_054085254.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_011186795.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_011177846.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054086879.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_028900328.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_011181128.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_028896358.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054083255.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054088865.1	11	Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-3000170;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-3560783	"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Syndecan interactions";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"Defective B4GALT7 causes EDS, progeroid type"
XP_054088623.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_011179263.1	1	Reactome: R-HSA-419771	"Opsins"
XP_011179224.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054089156.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_011188140.1	5	Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013	"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III"
XP_011196559.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011190994.2	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_011195080.1	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_011191438.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011184216.2	8	Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867	"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex"
XP_011184466.2	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_054088108.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_011196240.1	3	MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7888	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)"
XP_054087654.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_011187447.2	4	Reactome: R-HSA-196741;Reactome: R-HSA-8964011;Reactome: R-HSA-3359462;Reactome: R-HSA-3359463	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"HDL clearance";"Defective AMN causes hereditary megaloblastic anemia 1";"Defective CUBN causes hereditary megaloblastic anemia 1"
XP_011194568.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054084232.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_011188618.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054086267.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_054083771.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054082038.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_054085904.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011187545.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054081113.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_011194794.2	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_011190497.2	4	KEGG: 00900+2.5.1.87;MetaCyc: PWY-6129;Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Terpenoid backbone biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_011180753.2	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_011196553.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_011193198.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_054088629.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_011195589.1	4	Reactome: R-HSA-6790901;Reactome: R-HSA-156581;Reactome: R-HSA-6782315;Reactome: R-HSA-72764	"rRNA modification in the nucleus and cytosol";"Methylation";"tRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination"
XP_011181711.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-8948751	"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"Signal transduction by L1";"Synthesis of PC";"Regulation of PTEN stability and activity"
XP_011178458.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863	"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_028895068.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011180089.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_011184345.1	14	KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7035	"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis"
XP_011181792.2	5	Reactome: R-HSA-8937144;Reactome: R-HSA-211945;Reactome: R-HSA-211976;Reactome: R-HSA-211981;Reactome: R-HSA-1989781	"Aryl hydrocarbon receptor signalling";"Phase I - Functionalization of compounds";"Endogenous sterols";"Xenobiotics";"PPARA activates gene expression"
XP_054087212.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_011186010.2	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_011195418.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_011179521.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_011191434.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_011196399.2	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_054088067.1	12	Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;MetaCyc: PWY-7221	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Long-term potentiation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis"
XP_054083990.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_011178710.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_011190016.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_054091552.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_011193860.1	4	Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685	"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Macroautophagy";"Pink/Parkin Mediated Mitophagy"
XP_011194743.1	24	Reactome: R-HSA-163358;Reactome: R-HSA-4420097;Reactome: R-HSA-5621575;Reactome: R-HSA-111931;KEGG: 04150+2.7.11.11;Reactome: R-HSA-422356;Reactome: R-HSA-432040;Reactome: R-HSA-5610780;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-8853659;Reactome: R-HSA-163615;Reactome: R-HSA-392517;Reactome: R-HSA-381676;Reactome: R-HSA-5610783;Reactome: R-HSA-5610787;Reactome: R-HSA-5610785;Reactome: R-HSA-163560;Reactome: R-HSA-5687128;Reactome: R-HSA-9634600;Reactome: R-HSA-983231;Reactome: R-HSA-8963896;Reactome: R-HSA-164378;Reactome: R-HSA-9010642	"PKA-mediated phosphorylation of key metabolic factors";"VEGFA-VEGFR2 Pathway";"CD209 (DC-SIGN) signaling";"PKA-mediated phosphorylation of CREB";"mTOR signaling pathway";"Regulation of insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Degradation of GLI1 by the proteasome";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"RET signaling";"PKA activation";"Rap1 signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Degradation of GLI2 by the proteasome";"Hedgehog 'off' state";"GLI3 is processed to GLI3R by the proteasome";"Triglyceride catabolism";"MAPK6/MAPK4 signaling";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Factors involved in megakaryocyte development and platelet production";"HDL assembly";"PKA activation in glucagon signalling";"ROBO receptors bind AKAP5"
XP_054092043.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_011177225.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_028899969.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364	"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_011180934.2	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_011190713.1	57	Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-6798695;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-1236974	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neutrophil degranulation";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway"
XP_028894814.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_011179646.1	29	Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-167160;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-112382	"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex"
XP_011196845.1	3	MetaCyc: PWY-0;MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57	"Putrescine degradation III";"Spermine and spermidine degradation I";"Arginine and proline metabolism"
XP_054085551.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_011193671.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_011186150.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054088084.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68949	"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Orc1 removal from chromatin"
XP_054089854.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_054091611.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011185509.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-390471	"Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis"
XP_011178957.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011188277.1	12	MetaCyc: PWY-5132;MetaCyc: PWY-5108;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00620+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00630+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-6672;KEGG: 00010+6.2.1.1	"Lupulone and humulone biosynthesis";"L-isoleucine biosynthesis V";"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol";"Pyruvate metabolism";"Propanoate metabolism";"Methane metabolism";"Adlupulone and adhumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Colupulone and cohumulone biosynthesis";"Cis-genanyl-coa degradation";"Glycolysis / Gluconeogenesis"
XP_054091013.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054081605.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport"
XP_011188172.2	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_054088260.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_028901826.1	17	MetaCyc: PWY-6608;Reactome: R-HSA-6798695;MetaCyc: PWY-4202;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-5695;MetaCyc: PWY-6620;Reactome: R-HSA-74217;MetaCyc: PWY-6644;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6627;Reactome: R-HSA-74259;MetaCyc: PWY-5532;MetaCyc: PWY-6609;MetaCyc: PWY-6611;MetaCyc: PWY-7179-1;KEGG: 00230+2.4.2.1	"Guanosine nucleotides degradation III";"Neutrophil degranulation";"Arsenate detoxification I (mammalian)";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Inosine 5'-phosphate degradation";"Guanine and guanosine salvage";"Purine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Nicotinate and nicotinamide metabolism";"Salinosporamide A biosynthesis";"Purine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II";"Purine metabolism"
XP_054083850.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_054088452.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054092045.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_011177747.1	4	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription"
XP_011178407.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_011176541.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011181871.3	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_054088538.1	4	Reactome: R-HSA-2161541;Reactome: R-HSA-499943;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_011193831.2	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_011196208.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_011195736.2	9	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"tRNA modification in the nucleus and cytosol";"Thermogenesis";"mTOR signaling pathway"
XP_011191279.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011182896.2	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_011177837.2	10	Reactome: R-HSA-400206;Reactome: R-HSA-983231;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-9022699;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702;Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-9022692	"Regulation of lipid metabolism by PPARalpha";"Factors involved in megakaryocyte development and platelet production";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"Regulation of MECP2 expression and activity"
XP_011193646.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-5633231	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)"
XP_054089653.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_011186515.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011179671.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_054082911.1	10	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-69473	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint"
XP_054086488.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011176936.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054081603.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_011179860.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_011195921.2	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_054089051.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_011189713.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
XP_011195310.2	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_054082567.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054088579.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011183737.2	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_011190599.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_011187247.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_011182961.2	6	Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-72165	"RNA Polymerase II Transcription Termination";"snRNP Assembly";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway"
XP_054087859.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_028900151.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Clathrin-mediated endocytosis"
XP_054083540.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_054091101.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054090706.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_054090601.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_011190728.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport"
XP_054084844.1	7	Reactome: R-HSA-1855183;MetaCyc: PWY-4702;MetaCyc: PWY-6363;MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25	"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"Inositol phosphate metabolism"
XP_054084490.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-166166	"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade"
XP_054085102.1	3	Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14	"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_011179198.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_011187900.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011193465.2	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_011178133.2	4	Reactome: R-HSA-1660662;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119	"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_028893479.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011192916.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_011194292.1	3	KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3	"Glycine, serine and threonine metabolism";"Serine biosynthesis";"Methane metabolism"
XP_054090943.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054088869.1	11	Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-3000170;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-3560783	"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Syndecan interactions";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"Defective B4GALT7 causes EDS, progeroid type"
XP_011180420.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054083043.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_028895370.2	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_028898440.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_011178099.2	12	MetaCyc: PWY-5856;MetaCyc: PWY-5871;Reactome: R-HSA-1268020;MetaCyc: PWY-6708;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-5855;MetaCyc: PWY-6978;MetaCyc: PWY-5873;MetaCyc: PWY-5857	"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)"
XP_028899492.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_054091028.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054086674.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_028895274.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_011183932.2	5	Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_011196457.2	4	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_028897150.2	7	KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660499;Reactome: R-HSA-1660514;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660516;MetaCyc: PWY-6351;MetaCyc: PWY-6352	"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the Golgi membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis"
XP_054091596.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-5221030	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA"
XP_011179415.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_028900030.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011179038.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_011197070.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054091473.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364	"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_054081498.1	10	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-200425;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-1445148	"TP53 Regulates Metabolic Genes";"Macroautophagy";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_028901922.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_011193346.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_011188067.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054090998.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_011193877.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_011179371.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054083049.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_054088070.1	8	Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-442982	"Long-term potentiation";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_054090949.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_054088824.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_054088863.1	11	Reactome: R-HSA-202733;Reactome: R-HSA-3560783;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-3000170;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332	"Cell surface interactions at the vascular wall";"Defective B4GALT7 causes EDS, progeroid type";"Retinoid metabolism and transport";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Syndecan interactions";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1"
XP_054088277.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_011190297.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011187549.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_011179143.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_028897639.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_011193224.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_011190111.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_054086112.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_011188260.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
XP_011190476.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054086150.1	9	Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-4420332	"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1"
XP_011184554.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054089769.1	34	Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-9639288;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Amino acids regulate mTORC1";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"Separation of Sister Chromatids";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion"
XP_011191692.2	8	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5689880;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Ub-specific processing proteases";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_054082521.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_011186563.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054081609.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_054087545.1	27	Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-159231	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_011186417.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054084120.1	9	MetaCyc: PWY-6367;Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-7039	"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule"
XP_011192401.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-381183;Reactome: R-HSA-2426168	"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)"
XP_011177750.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_028894606.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_011180011.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_011180829.2	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_028896450.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_011189582.2	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_011189765.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_011181591.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054082741.1	3	Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725	"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation";"Protein methylation"
XP_011190359.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_054082646.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_054088618.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_011196958.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_028897077.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_028893560.2	8	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-6804115;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_011190066.2	27	Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-3301854	"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly"
XP_054084345.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054086077.1	24	Reactome: R-HSA-1257604;Reactome: R-HSA-165158;KEGG: 04151+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-389357;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2871837;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-444257;Reactome: R-HSA-354192;Reactome: R-HSA-202424;Reactome: R-HSA-5625740;Reactome: R-HSA-5218920;Reactome: R-HSA-2730905;Reactome: R-HSA-6804757;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5607764;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-392451	"PIP3 activates AKT signaling";"Activation of AKT2";"PI3K-Akt signaling pathway";"GPVI-mediated activation cascade";"CD28 dependent PI3K/Akt signaling";"Relaxin signaling pathway";"FCERI mediated NF-kB activation";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"VEGFR2 mediated cell proliferation";"RSK activation";"Integrin signaling";"Downstream TCR signaling";"RHO GTPases activate PKNs";"VEGFR2 mediated vascular permeability";"Role of LAT2/NTAL/LAB on calcium mobilization";"Regulation of TP53 Degradation";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"CLEC7A (Dectin-1) signaling";"Thermogenesis";"Estrogen-stimulated signaling through PRKCZ";"G beta:gamma signalling through PI3Kgamma"
XP_054089686.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_011196395.2	6	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_011180539.1	17	Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6790901;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72702	"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"rRNA modification in the nucleus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition"
XP_054082281.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_054083173.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_011188629.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-8060;MetaCyc: PWY-7180;Reactome: R-HSA-71336;KEGG: 00030+4.1.2.4	"Neutrophil degranulation";"2-deoxy-D-ribose degradation I";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_028902123.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_028893647.1	22	Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-389513;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-5358749	"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"CTLA4 inhibitory signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated"
XP_011179129.2	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_011190748.2	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054089162.1	6	Reactome: R-HSA-76005;Reactome: R-HSA-114516;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13	"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Phosphatidylinositol signaling system"
XP_011190528.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054089925.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_028899768.2	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_011188398.2	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_011179912.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011190581.1	6	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-6798695	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Neutrophil degranulation"
XP_011183883.2	8	MetaCyc: PWY-7179;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-6609;Reactome: R-HSA-5683826;MetaCyc: PWY-6611	"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Adenine and adenosine salvage III";"Surfactant metabolism";"Adenine and adenosine salvage V"
XP_054086582.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_028895622.2	16	Reactome: R-HSA-1250196;Reactome: R-HSA-8847993;Reactome: R-HSA-1250347;Reactome: R-HSA-1227986;Reactome: R-HSA-1251985;Reactome: R-HSA-1963640;Reactome: R-HSA-9664565;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-1250342;Reactome: R-HSA-1236394;Reactome: R-HSA-5673001;Reactome: R-HSA-6785631;Reactome: R-HSA-1963642;Reactome: R-HSA-6811558;Reactome: R-HSA-8863795	"SHC1 events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"SHC1 events in ERBB4 signaling";"Signaling by ERBB2";"Nuclear signaling by ERBB4";"GRB2 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI3K events in ERBB4 signaling";"Signaling by ERBB4";"RAF/MAP kinase cascade";"ERBB2 Regulates Cell Motility";"PI3K events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Downregulation of ERBB2 signaling"
XP_011191731.2	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_011193357.2	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_011190838.1	27	Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638	"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"snRNP Assembly";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins"
XP_028900849.2	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_028896373.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_011185732.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_028894778.2	10	Reactome: R-HSA-2151209;Reactome: R-HSA-200425;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354	"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism";"TP53 Regulates Metabolic Genes";"Macroautophagy";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Lipophagy"
XP_054084534.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_011192892.2	3	Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517	"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane"
XP_054086003.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_011187833.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_011192811.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942	"Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism"
XP_011188232.2	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_028894196.2	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054082597.1	13	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802948	"Human cytomegalovirus infection";"Human papillomavirus infection";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Thermogenesis";"PI3K-Akt signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Relaxin signaling pathway";"Signaling by high-kinase activity BRAF mutants"
XP_011181264.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_011179866.2	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_011185015.1	8	MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-8086	"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Propanoate metabolism";"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_011189639.1	10	MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-5030;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-3841;MetaCyc: PWY-7909;Reactome: R-HSA-196757;MetaCyc: PWY-2201	"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"Metabolism of folate and pterines";"Folate transformations I"
XP_054089918.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_011186353.2	9	Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_054088959.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_028898701.2	5	Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122	"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_054081988.1	8	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Activation of RAC1";"Relaxin signaling pathway"
XP_054082293.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_028900457.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_054088899.1	33	Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-73779;Reactome: R-HSA-69273;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-69202;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-69656;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-69231;Reactome: R-HSA-8939236;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-6796648	"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"Cyclin D associated events in G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes"
XP_011189112.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054088986.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054082816.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_054086441.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054091312.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_054087427.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_028896679.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_011195128.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_011179604.1	7	Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_011196701.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011177789.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011182832.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_011195711.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_011187878.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288	"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1"
XP_054088209.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_028896285.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054090968.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_011189565.2	7	Reactome: R-HSA-5362798;Reactome: R-HSA-5635838;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5658034	"Release of Hh-Np from the secreting cell";"Activation of SMO";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"HHAT G278V abrogates palmitoylation of Hh-Np"
XP_011185971.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_011184623.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011186386.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011178661.2	8	KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2	"Oxidative phosphorylation";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Photosynthesis"
XP_011190060.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
XP_011181712.1	10	Reactome: R-HSA-6798695;Reactome: R-HSA-201688;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-8934903;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853	"Neutrophil degranulation";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Synthesis of PC";"Signal transduction by L1";"Receptor Mediated Mitophagy";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes"
XP_011191703.3	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_054083977.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_011190873.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_011193269.3	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_054088953.1	10	KEGG: 00900+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-922;MetaCyc: PWY-6174;KEGG: 00072+2.3.3.10;KEGG: 00280+2.3.3.10;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7524;MetaCyc: PWY-7391;MetaCyc: PWY-7571	"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Ferrichrome A biosynthesis"
XP_054087835.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_011186680.3	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054087634.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_028895771.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_028902168.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011185766.2	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_011189633.1	11	Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_011193293.1	4	MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism"
XP_011189674.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_011194859.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_028896461.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_028893650.1	22	Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-389513;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337	"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CTLA4 inhibitory signaling";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding"
XP_011186593.1	40	Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-5578749;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6803529;Reactome: R-HSA-72165;Reactome: R-HSA-6782135;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-5601884;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-5617472;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-72203	"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcriptional regulation by small RNAs";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"FGFR2 alternative splicing";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Processing of Capped Intron-Containing Pre-mRNA"
XP_028900843.2	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_054091612.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_028895812.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_028901837.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_054088451.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_011178473.1	56	Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323	"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling"
XP_054091650.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_011183617.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_028894426.2	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_011180204.2	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
XP_011178596.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_054089515.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054087197.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011196868.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72165	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway"
XP_011188409.2	8	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_011181268.2	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_028900733.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_011177804.1	3	MetaCyc: PWY-5996;Reactome: R-HSA-75105;MetaCyc: PWY-5987	"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis";"Sorgoleone biosynthesis"
XP_054085510.1	1	Reactome: R-HSA-3000178	"ECM proteoglycans"
XP_011178790.1	8	KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1	"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Glycolysis";"Starch and sucrose metabolism";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis"
XP_011195449.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011196365.2	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_011193672.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_011179164.2	57	Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-211733	"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_028900036.1	6	Reactome: R-HSA-1369062;Reactome: R-HSA-2046106;Reactome: R-HSA-9603798;Reactome: R-HSA-390247;Reactome: R-HSA-2046105;Reactome: R-HSA-5684045	"ABC transporters in lipid homeostasis";"alpha-linolenic acid (ALA) metabolism";"Class I peroxisomal membrane protein import";"Beta-oxidation of very long chain fatty acids";"Linoleic acid (LA) metabolism";"Defective ABCD1 causes adrenoleukodystrophy (ALD)"
XP_011194236.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_011180160.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011184460.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_028900845.2	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_054089484.1	8	MetaCyc: PWY-7179;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-6609;MetaCyc: PWY-6611;Reactome: R-HSA-5683826	"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Surfactant metabolism"
XP_011176927.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054084477.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_011195922.2	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_054089052.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_054088800.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_011181148.2	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_011177730.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis"
XP_054081223.1	5	KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614	"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Pyrimidine metabolism";"Pyrimidine salvage"
XP_011187427.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_011191312.1	5	Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-389357	"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling"
XP_011193200.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214	"Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs"
XP_011193608.2	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_011188203.1	4	Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16	"Metabolism of polyamines";"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism"
XP_011191391.2	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_011177536.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_054084813.1	8	MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;Reactome: R-HSA-5683826;MetaCyc: PWY-6609	"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Neutrophil degranulation";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Surfactant metabolism";"Adenine and adenosine salvage III"
XP_011180780.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_054089513.1	14	MetaCyc: PWY-3781;MetaCyc: PWY-6969;MetaCyc: PWY-4302;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-561;Reactome: R-HSA-611105;MetaCyc: PWY-7254;KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1	"Aerobic respiration I (cytochrome c)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration III (alternative oxidase pathway)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Butanoate metabolism"
XP_011188146.2	7	MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466	"Betanidin degradation";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis"
XP_011181033.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011188899.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_011195632.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054089217.1	12	Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167238	"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation"
XP_011177840.2	10	Reactome: R-HSA-983231;Reactome: R-HSA-400206;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-9022699;Reactome: R-HSA-9022692	"Factors involved in megakaryocyte development and platelet production";"Regulation of lipid metabolism by PPARalpha";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates neuronal receptors and channels";"Regulation of MECP2 expression and activity"
XP_011188848.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_011179326.2	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_028896874.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_028897781.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011185159.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011192889.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011186968.3	14	MetaCyc: PWY-7036;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725	"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_028896906.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_011187334.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_011191647.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-8953750	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6"
XP_054085479.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206296;Reactome: R-HSA-2024101	"HS-GAG degradation";"MPS II - Hunter syndrome";"CS/DS degradation"
XP_054084104.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_054088694.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_028897807.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_011191705.3	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_011191908.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054088895.1	6	Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_054091841.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011176481.1	22	Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_011189563.2	8	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_011179058.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011179293.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_011189635.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway"
XP_054086807.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054086130.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_054091102.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_011184534.1	5	MetaCyc: PWY-6558;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656237	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT2 causes exostoses 2"
XP_054091180.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054086548.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation"
XP_028900152.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis"
XP_011179816.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054084668.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011185630.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379	"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events"
XP_011187141.2	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_054088955.1	10	KEGG: 00650+2.3.3.10;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-7571;MetaCyc: PWY-7524;Reactome: R-HSA-1989781;KEGG: 00900+2.3.3.10;MetaCyc: PWY-922;MetaCyc: PWY-6174;KEGG: 00072+2.3.3.10	"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Isoprene biosynthesis II (engineered)";"Ferrichrome A biosynthesis";"Mevalonate pathway III (archaea)";"PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Synthesis and degradation of ketone bodies"
XP_011191048.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_054085101.1	3	Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14	"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_011181464.2	16	Reactome: R-HSA-209543;Reactome: R-HSA-5603041;Reactome: R-HSA-9020702;Reactome: R-HSA-5602498;Reactome: R-HSA-1810476;Reactome: R-HSA-166058;Reactome: R-HSA-6811558;Reactome: R-HSA-1236974;Reactome: R-HSA-975155;Reactome: R-HSA-5603037;Reactome: R-HSA-5602680;Reactome: R-HSA-3134963;Reactome: R-HSA-975138;Reactome: R-HSA-975871;Reactome: R-HSA-1257604;Reactome: R-HSA-975110	"p75NTR recruits signalling complexes";"IRAK4 deficiency (TLR2/4)";"Interleukin-1 signaling";"MyD88 deficiency (TLR2/4)";"RIP-mediated NFkB activation via ZBP1";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ER-Phagosome pathway";"MyD88 dependent cascade initiated on endosome";"IRAK4 deficiency (TLR5)";"MyD88 deficiency (TLR5)";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane";"PIP3 activates AKT signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling"
XP_054090680.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_054082604.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_028894348.2	6	Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6803204;Reactome: R-HSA-139915	"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria"
XP_054086111.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_011186858.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011193604.1	19	Reactome: R-HSA-8856828;Reactome: R-HSA-3000471;Reactome: R-HSA-8964046;Reactome: R-HSA-3000480;Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-8963888;Reactome: R-HSA-8856825;Reactome: R-HSA-5686938;Reactome: R-HSA-202733;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038;Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-8866423	"Clathrin-mediated endocytosis";"Scavenging by Class B Receptors";"VLDL clearance";"Scavenging by Class A Receptors";"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"Chylomicron remodeling";"Retinoid metabolism and transport";"Chylomicron assembly";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Cell surface interactions at the vascular wall";"LDL remodeling";"Scavenging by Class H Receptors";"Post-translational protein phosphorylation";"LDL clearance";"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL assembly"
XP_011176961.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_011182357.2	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_054086297.1	4	KEGG: 00561+2.7.1.30;Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions";"Glycerol degradation I"
XP_011191691.2	11	Reactome: R-HSA-5693607;Reactome: R-HSA-69166;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-174437;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_054082295.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_011186355.2	5	Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3	"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes"
XP_054086476.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_011191612.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_011189569.2	6	Reactome: R-HSA-8957275;Reactome: R-HSA-5626467;Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Post-translational protein phosphorylation";"RHO GTPases activate IQGAPs";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_054081660.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_011176776.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_028895098.1	2	Reactome: R-HSA-4570571;Reactome: R-HSA-446193	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_054085596.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054090380.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_028897359.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
XP_054088097.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-164378	"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (z) signalling events";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling"
XP_028898753.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_011187456.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_011196369.2	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_054089700.1	10	MetaCyc: PWY-6372;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6369;MetaCyc: PWY-6554	"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)"
XP_028895572.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_011189838.2	27	Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159230	"Transcriptional regulation by small RNAs";"snRNP Assembly";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA"
XP_011177997.2	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054090060.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23	"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_011188893.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_011193444.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_054084368.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_054086945.1	11	Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-69166;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-174437;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756	"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Removal of the Flap Intermediate from the C-strand";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation"
XP_011176989.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_011185330.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054082282.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_054089923.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_011191044.1	34	Reactome: R-HSA-69202;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-69273;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-69231;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-8939236;Reactome: R-HSA-75953;Reactome: R-HSA-69656;Reactome: R-HSA-6807505;Reactome: R-HSA-76042	"Cyclin E associated events during G1/S transition";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Cyclin D associated events in G1";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_054083704.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
XP_011180012.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_054081229.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_011192402.1	20	MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-6920;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-7574;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7858;MetaCyc: PWY-6837;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6	"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism"
XP_054091777.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_054090524.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_054091458.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex"
XP_011179400.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_011190374.1	4	KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48	"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Pyrimidine metabolism"
XP_011195591.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation"
XP_011195789.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011189528.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_011178685.2	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_011182299.1	4	Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I"
XP_054086005.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054082742.1	3	KEGG: 00310+2.1.1.60;Reactome: R-HSA-2514859;Reactome: R-HSA-8876725	"Lysine degradation";"Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation"
XP_011193950.1	4	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_011183772.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_011176463.1	6	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway"
XP_011181592.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_028893777.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_054084974.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_011189581.2	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054084335.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport"
XP_011184964.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_011185776.2	12	MetaCyc: PWY-6708;MetaCyc: PWY-5856;MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;MetaCyc: PWY-5870;MetaCyc: PWY-7233;MetaCyc: PWY-5871;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5857;MetaCyc: PWY-5873;MetaCyc: PWY-5855	"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)"
XP_011189088.1	14	Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398	"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Ca2+ pathway"
XP_011187105.1	11	Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-5689880;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161	"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Ub-specific processing proteases";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation"
XP_011196289.2	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_011187578.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054081910.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054088111.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_011186451.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-4615885	"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins"
XP_028895666.1	8	Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-164378	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"PKA activation in glucagon signalling"
XP_011182532.2	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_054083984.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_054090364.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_054091770.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_054081952.1	4	KEGG: 00564+3.1.1.7;Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Glycerophospholipid metabolism";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_054082000.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_028893866.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054082082.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_011177812.2	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_054081892.1	24	Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-437239	"COPI-mediated anterograde transport";"Aggrephagy";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"RHO GTPases Activate Formins";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1"
XP_054081757.1	4	MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32	"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism"
XP_028901154.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011180354.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054091493.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis"
XP_054084528.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758	"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation"
XP_011196798.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_054090387.1	6	Reactome: R-HSA-5099900;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-114516	"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation"
XP_011193509.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_054082731.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_028895605.2	15	Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408	"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Ca2+ pathway";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation"
XP_054086205.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054081667.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_011192921.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_011179133.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054086097.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_011178149.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_011177322.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_011181670.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054091129.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_011196878.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_011197066.2	1	Reactome: R-HSA-5676934	"Protein repair"
XP_028900764.2	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_011177453.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553	"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs"
XP_028896818.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_054081684.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_011177504.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_011192736.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_011197005.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_011184339.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_011181704.2	4	Reactome: R-HSA-8849175;Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Threonine catabolism";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_011191118.1	15	Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-9603505;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167158	"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"NTRK3 as a dependence receptor";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex"
XP_054086394.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_011178956.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054091851.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_054090939.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_028895053.1	8	KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1	"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Glycolysis";"Starch and sucrose metabolism";"Galactose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_011188565.3	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_054083039.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_011189754.2	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_054083033.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_054090687.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_054090933.1	56	Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-174178	"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_054086800.1	3	Reactome: R-HSA-114508;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13	"Effects of PIP2 hydrolysis";"G alpha (z) signalling events";"Phosphatidylinositol signaling system"
XP_054086137.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_011178415.2	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_054091608.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_011187030.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_011183942.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011184678.1	18	KEGG: 00240+2.4.2.3;MetaCyc: PWY-6608;MetaCyc: PWY-4202;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5695;Reactome: R-HSA-73621;MetaCyc: PWY-6620;MetaCyc: PWY-6644;MetaCyc: PWY-6627;KEGG: 00760+2.4.2.1;MetaCyc: PWY-5532;MetaCyc: PWY-6609;Reactome: R-HSA-73614;MetaCyc: PWY-6611;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179-1	"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Drug metabolism - other enzymes";"Inosine 5'-phosphate degradation";"Pyrimidine catabolism";"Guanine and guanosine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Salinosporamide A biosynthesis";"Nicotinate and nicotinamide metabolism";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage III";"Pyrimidine salvage";"Adenine and adenosine salvage V";"Purine metabolism";"Purine deoxyribonucleosides degradation II"
XP_011176475.1	22	Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"RAF activation";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_028902099.2	8	Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-381676	"PKA activation in glucagon signalling";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_011182044.2	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_011187619.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_011185637.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation"
XP_028896363.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054087103.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation"
XP_054087938.1	10	Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-3214847;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167162	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HATs acetylate histones";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape"
XP_011196430.2	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_011190140.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_028897882.2	11	MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-6549;KEGG: 00720+1.1.1.42;MetaCyc: PWY-5913	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Ethylene biosynthesis V (engineered)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"L-glutamine biosynthesis III";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)"
XP_011187574.2	4	KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-5737;MetaCyc: PWY-6922	"Arginine and proline metabolism";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis"
XP_054090664.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054083199.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011178983.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054090865.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_011194152.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054083921.1	3	KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5	"Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation"
XP_011187975.1	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32	"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism"
XP_011192511.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_011179139.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_011185927.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_054089172.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-76005	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+"
XP_054089534.1	5	Reactome: R-HSA-75896;Reactome: R-HSA-9033241;MetaCyc: PWY-7782;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033500	"Plasmalogen biosynthesis";"Peroxisomal protein import";"Plasmalogen biosynthesis";"Ether lipid metabolism";"TYSND1 cleaves peroxisomal proteins"
XP_011190980.2	3	Reactome: R-HSA-3899300;Reactome: R-HSA-9609690;Reactome: R-HSA-6804757	"SUMOylation of transcription cofactors";"HCMV Early Events";"Regulation of TP53 Degradation"
XP_011182904.2	3	Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_054081621.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_028898874.1	6	Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_011181708.1	10	Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-6804756	"Signal transduction by L1";"Regulation of PTEN stability and activity";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Regulation of TP53 Activity through Phosphorylation"
XP_011177847.2	6	MetaCyc: PWY-5744;Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-4381;MetaCyc: PWY-5789;MetaCyc: PWY-5743	"Glyoxylate assimilation";"Biotin transport and metabolism";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle"
XP_054090754.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_011192429.1	22	MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7727;MetaCyc: PWY-7035;MetaCyc: PWY-7728;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7053;MetaCyc: PWY-8041;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7592;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7049;MetaCyc: PWY-5353;MetaCyc: PWY-6958;MetaCyc: PWY-7726;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7606	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)"
XP_054081202.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_011183195.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_011176946.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054087979.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_054081546.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_011185194.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis"
XP_011188719.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_054091499.1	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_054083487.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_054088807.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-418555	"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"G alpha (s) signalling events"
XP_011193926.1	5	KEGG: 00010+4.1.1.32;Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32	"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Citrate cycle (TCA cycle)"
XP_054081740.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_054092035.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_011179904.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_028894291.2	9	Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER"
XP_011187958.3	6	Reactome: R-HSA-110362;Reactome: R-HSA-73933;Reactome: R-HSA-110373;Reactome: R-HSA-73930;Reactome: R-HSA-110357;Reactome: R-HSA-5651801	"POLB-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Displacement of DNA glycosylase by APEX1";"PCNA-Dependent Long Patch Base Excision Repair"
XP_011179760.2	24	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2871837;KEGG: 04926+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-114604;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-165158;Reactome: R-HSA-9634635;KEGG: 04714+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-5607764;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-2730905;Reactome: R-HSA-5218920;Reactome: R-HSA-5625740;Reactome: R-HSA-202424;Reactome: R-HSA-354192;Reactome: R-HSA-444257;Reactome: R-HSA-5218921	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"FCERI mediated NF-kB activation";"Relaxin signaling pathway";"CD28 dependent PI3K/Akt signaling";"GPVI-mediated activation cascade";"PI3K-Akt signaling pathway";"PIP3 activates AKT signaling";"Activation of AKT2";"Estrogen-stimulated signaling through PRKCZ";"Thermogenesis";"G beta:gamma signalling through PI3Kgamma";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"Regulation of TP53 Degradation";"Role of LAT2/NTAL/LAB on calcium mobilization";"VEGFR2 mediated vascular permeability";"RHO GTPases activate PKNs";"Downstream TCR signaling";"Integrin signaling";"RSK activation";"VEGFR2 mediated cell proliferation"
XP_011182551.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011184150.2	11	Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497	"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_011192585.2	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_054081367.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011176920.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_028894462.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_011190629.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_011191991.1	2	Reactome: R-HSA-203615;Reactome: R-HSA-8981607	"eNOS activation";"Intracellular oxygen transport"
XP_054086209.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011191912.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_011186558.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_011192002.2	57	Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764	"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling"
XP_054085424.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-164378	"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Purine metabolism";"G alpha (z) signalling events";"G alpha (s) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation in glucagon signalling"
XP_011177572.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_011179082.1	26	Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-389960;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-389977;Reactome: R-HSA-6807878	"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Gap junction assembly";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport"
XP_011179207.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_054083791.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011183610.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_054092033.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_011192182.1	5	MetaCyc: PWY-6692;MetaCyc: PWY-7279;MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781	"Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)"
XP_011178911.2	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_011189869.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
YP_004891171.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_011181235.2	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_011196634.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054091118.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_028901280.2	9	Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400253	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Circadian Clock"
XP_028901830.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_028894121.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011182926.1	11	Reactome: R-HSA-5668599;Reactome: R-HSA-1660514;Reactome: R-HSA-1660499;Reactome: R-HSA-168138;Reactome: R-HSA-109704;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660517;Reactome: R-HSA-1632852;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660516	"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the plasma membrane";"Toll Like Receptor 9 (TLR9) Cascade";"PI3K Cascade";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Synthesis of PIPs at the late endosome membrane";"Macroautophagy";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane"
XP_011189140.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054083035.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_054090496.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_011190084.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_028897773.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011190410.1	24	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-190861	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Aggrephagy";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Gap junction assembly"
XP_054084700.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_028896365.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054087105.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Aggrephagy";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic"
XP_054081996.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054083268.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_054081889.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_011197009.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs"
XP_011184335.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011176473.1	22	Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-432142;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Platelet sensitization by LDL";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_054087578.1	14	MetaCyc: PWY-7411;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-5667	"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I"
XP_028898197.2	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_011178567.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011187381.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011188192.2	3	Reactome: R-HSA-9609736;Reactome: R-HSA-212676;Reactome: R-HSA-6794361	"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins"
XP_054084519.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054090824.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054086734.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_054088016.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_054090625.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_054091784.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_054082822.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054085961.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-204005	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport"
XP_054088998.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500	"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle"
XP_011184799.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054081856.1	57	Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5676590	"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling"
XP_054082099.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_011192195.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_011180993.1	15	KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-5484;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-7003;MetaCyc: PWY-7218	"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)"
XP_011196197.1	5	Reactome: R-HSA-162699;Reactome: R-HSA-4719360;Reactome: R-HSA-162710;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377	"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of glycosylphosphatidylinositol (GPI)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)"
XP_011180718.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054084633.1	3	KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695	"Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation"
XP_028897645.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_054087319.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_011181029.1	22	Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-432142	"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL"
XP_011196211.1	2	Reactome: R-HSA-8983711;Reactome: R-HSA-909733	"OAS antiviral response";"Interferon alpha/beta signaling"
XP_011181023.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054087420.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_054084484.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_011184096.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_011189314.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054082796.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_054082691.1	56	Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091	"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Activation of NF-kappaB in B cells"
XP_011189460.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054081827.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_054084639.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054088719.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_011183423.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_011185419.2	33	Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-168276	"tRNA processing in the nucleus";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"Separation of Sister Chromatids";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways"
XP_011194778.1	182	Reactome: R-HSA-182971;Reactome: R-HSA-937072;Reactome: R-HSA-9033241;Reactome: R-HSA-2644606;Reactome: R-HSA-2173788;Reactome: R-HSA-5693565;Reactome: R-HSA-450321;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-975144;Reactome: R-HSA-72702;Reactome: R-HSA-6783310;Reactome: R-HSA-2691232;Reactome: R-HSA-68949;Reactome: R-HSA-179409;Reactome: R-HSA-450408;Reactome: R-HSA-2173796;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-72695;Reactome: R-HSA-1295596;Reactome: R-HSA-211733;Reactome: R-HSA-175474;Reactome: R-HSA-209543;Reactome: R-HSA-2173791;Reactome: R-HSA-975163;Reactome: R-HSA-201681;Reactome: R-HSA-5678895;Reactome: R-HSA-8948747;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-9613829;Reactome: R-HSA-936440;Reactome: R-HSA-5676590;Reactome: R-HSA-912631;Reactome: R-HSA-174113;Reactome: R-HSA-5205685;Reactome: R-HSA-5696395;Reactome: R-HSA-2122948;Reactome: R-HSA-8876493;Reactome: R-HSA-1169091;Reactome: R-HSA-5696400;Reactome: R-HSA-5632684;Reactome: R-HSA-4641258;Reactome: R-HSA-1236382;Reactome: R-HSA-180534;Reactome: R-HSA-8875360;Reactome: R-HSA-209560;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-1358803;Reactome: R-HSA-8854050;Reactome: R-HSA-937041;Reactome: R-HSA-975956;Reactome: R-HSA-4608870;Reactome: R-HSA-937039;Reactome: R-HSA-975957;Reactome: R-HSA-6804760;Reactome: R-HSA-8852276;Reactome: R-HSA-5656121;Reactome: R-HSA-9637628;Reactome: R-HSA-5689896;Reactome: R-HSA-69017;Reactome: R-HSA-9013507;Reactome: R-HSA-3322077;Reactome: R-HSA-5684264;Reactome: R-HSA-2565942;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-168638;Reactome: R-HSA-174084;Reactome: R-HSA-5685942;Reactome: R-HSA-977225;Reactome: R-HSA-8866654;Reactome: R-HSA-2559580;Reactome: R-HSA-2979096;Reactome: R-HSA-936964;Reactome: R-HSA-72706;Reactome: R-HSA-382556;Reactome: R-HSA-9615710;Reactome: R-HSA-983168;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-156827;Reactome: R-HSA-2559582;Reactome: R-HSA-532668;Reactome: R-HSA-5654726;Reactome: R-HSA-5675221;Reactome: R-HSA-8863795;Reactome: R-HSA-5655862;Reactome: R-HSA-3134975;Reactome: R-HSA-3769402;Reactome: R-HSA-2871837;Reactome: R-HSA-1799339;Reactome: R-HSA-8939236;Reactome: R-HSA-975110;Reactome: R-HSA-5658442;Reactome: R-HSA-72649;Reactome: R-HSA-2122947;Reactome: R-HSA-6804756;Reactome: R-HSA-917729;Reactome: R-HSA-2672351;Reactome: R-HSA-6781827;Reactome: R-HSA-9645460;Reactome: R-HSA-450302;Reactome: R-HSA-8856828;Reactome: R-HSA-195253;Reactome: R-HSA-110314;Reactome: R-HSA-3785653;Reactome: R-HSA-2894862;Reactome: R-HSA-174048;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8866652;Reactome: R-HSA-9633012;Reactome: R-HSA-9646399;Reactome: R-HSA-4641263;Reactome: R-HSA-69231;Reactome: R-HSA-5689877;Reactome: R-HSA-5607764;Reactome: R-HSA-156902;Reactome: R-HSA-2559585;Reactome: R-HSA-5689901;Reactome: R-HSA-168928;Reactome: R-HSA-2173795;Reactome: R-HSA-5357905;Reactome: R-HSA-5693607;Reactome: R-HSA-69601;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-6782210;Reactome: R-HSA-5607761;Reactome: R-HSA-6791226;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-917937;Reactome: R-HSA-5654727;Reactome: R-HSA-6807004;Reactome: R-HSA-5696394;Reactome: R-HSA-174154;Reactome: R-HSA-69541;Reactome: R-HSA-174184;Reactome: R-HSA-2408557;Reactome: R-HSA-400253;Reactome: R-HSA-75815;Reactome: R-HSA-205043;Reactome: R-HSA-110320;Reactome: R-HSA-6804757;Reactome: R-HSA-937042;Reactome: R-HSA-9013973;Reactome: R-HSA-445989;Reactome: R-HSA-8856825;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-9636383;Reactome: R-HSA-68827;Reactome: R-HSA-5654732;Reactome: R-HSA-8849469;Reactome: R-HSA-1234176;Reactome: R-HSA-168927;Reactome: R-HSA-901032;Reactome: R-HSA-9604323;Reactome: R-HSA-5656169;Reactome: R-HSA-174490;Reactome: R-HSA-8948751;Reactome: R-HSA-5654733;Reactome: R-HSA-9014325;Reactome: R-HSA-5357956;Reactome: R-HSA-4641257;Reactome: R-HSA-5675482;Reactome: R-HSA-1169408;Reactome: R-HSA-72764;Reactome: R-HSA-1253288;Reactome: R-HSA-8951664;Reactome: R-HSA-162588	"EGFR downregulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Peroxisomal protein import";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Downregulation of TGF-beta receptor signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Ribosomal scanning and start codon recognition";"Fanconi Anemia Pathway";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Orc1 removal from chromatin";"APC-Cdc20 mediated degradation of Nek2A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Formation of the ternary complex, and subsequently, the 43S complex";"Spry regulation of FGF signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Assembly Of The HIV Virion";"p75NTR recruits signalling complexes";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TCF dependent signaling in response to WNT";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN localization";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Chaperone Mediated Autophagy";"Negative regulators of DDX58/IFIH1 signaling";"NIK-->noncanonical NF-kB signaling";"Regulation of signaling by CBL";"SCF-beta-TrCP mediated degradation of Emi1";"Pink/Parkin Mediated Mitophagy";"Formation of Incision Complex in GG-NER";"Activated NOTCH1 Transmits Signal to the Nucleus";"InlA-mediated entry of Listeria monocytogenes into host cells";"Activation of NF-kappaB in B cells";"Dual Incision in GG-NER";"Hedgehog 'on' state";"Degradation of DVL";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Vpu mediated degradation of CD4";"InlB-mediated entry of Listeria monocytogenes into host cell";"NF-kB is activated and signals survival";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Downregulation of ERBB2:ERBB3 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"IKK complex recruitment mediated by RIP1";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Asymmetric localization of PCP proteins";"IRAK1 recruits IKK complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of TP53 Activity through Methylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translesion synthesis by POLI";"Modulation by Mtb of host immune system";"Ovarian tumor domain proteases";"CDK-mediated phosphorylation and removal of Cdc6";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Glycogen synthesis";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of PLK1 Activity at G2/M Transition";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"NOD1/2 Signaling Pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"HDR through Homologous Recombination (HRR)";"Amyloid fiber formation";"E3 ubiquitin ligases ubiquitinate target proteins";"Oxidative Stress Induced Senescence";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ABC-family proteins mediated transport";"Late endosomal microautophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"L13a-mediated translational silencing of Ceruloplasmin expression";"Senescence-Associated Secretory Phenotype (SASP)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Negative regulation of FGFR1 signaling";"Negative regulation of MAPK pathway";"Downregulation of ERBB2 signaling";"Translesion synthesis by POLK";"Regulation of innate immune responses to cytosolic DNA";"Deactivation of the beta-catenin transactivating complex";"FCERI mediated NF-kB activation";"SRP-dependent cotranslational protein targeting to membrane";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Regulation of RAS by GAPs";"Translation initiation complex formation";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of TP53 Activity through Phosphorylation";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Stimuli-sensing channels";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Alpha-protein kinase 1 signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Clathrin-mediated endocytosis";"Degradation of beta-catenin by the destruction complex";"Recognition of DNA damage by PCNA-containing replication complex";"Myoclonic epilepsy of Lafora";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"APC/C:Cdc20 mediated degradation of Cyclin B";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aggrephagy";"Regulation of FZD by ubiquitination";"Cyclin D associated events in G1";"Josephin domain DUBs";"CLEC7A (Dectin-1) signaling";"Peptide chain elongation";"Oncogene Induced Senescence";"Metalloprotease DUBs";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Regulation of TNFR1 signaling";"Processing of DNA double-strand break ends";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dectin-1 mediated noncanonical NF-kB signaling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Iron uptake and transport";"Negative regulation of FGFR2 signaling";"Negative regulation of MET activity";"DNA Damage Recognition in GG-NER";"APC/C:Cdc20 mediated degradation of Securin";"Stabilization of p53";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Selenocysteine synthesis";"Circadian Clock";"Ubiquitin-dependent degradation of Cyclin D";"NRIF signals cell death from the nucleus";"Translesion Synthesis by POLH";"Regulation of TP53 Degradation";"IRAK2 mediated activation of TAK1 complex";"TICAM1-dependent activation of IRF3/IRF7";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Cargo recognition for clathrin-mediated endocytosis";"Separation of Sister Chromatids";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Prevention of phagosomal-lysosomal fusion";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of FGFR3 signaling";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TICAM1, RIP1-mediated IKK complex recruitment";"ER Quality Control Compartment (ERQC)";"Negative regulation of NOTCH4 signaling";"Termination of translesion DNA synthesis";"Membrane binding and targetting of GAG proteins";"Regulation of PTEN stability and activity";"Negative regulation of FGFR4 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"Degradation of AXIN";"Regulation of necroptotic cell death";"ISG15 antiviral mechanism";"Eukaryotic Translation Termination";"Downregulation of ERBB4 signaling";"Neddylation";"Budding and maturation of HIV virion"
XP_054081708.1	5	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.10;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
XP_054092078.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_054084052.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_028898928.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054083195.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_011186403.2	12	Reactome: R-HSA-6811436;Reactome: R-HSA-381038;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518	"COPI-independent Golgi-to-ER retrograde traffic";"XBP1(S) activates chaperone genes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2"
XP_011182957.1	12	Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-977225;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-205043	"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus"
XP_054081370.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_028898334.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011181367.1	8	Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-432040	"PKA activation in glucagon signalling";"DARPP-32 events";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_054086432.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_011177720.2	14	MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_054091482.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_011190431.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;Reactome: R-HSA-8964539	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism"
XP_028896420.2	14	MetaCyc: PWY-4302;MetaCyc: PWY-6969;MetaCyc: PWY-3781;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-7254;Reactome: R-HSA-611105;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;KEGG: 00650+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-7279;KEGG: 00020+1.3.5.1;KEGG: 00190+1.3.5.1	"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration I (cytochrome c)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Butanoate metabolism";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Citrate cycle (TCA cycle)";"Oxidative phosphorylation"
XP_054082590.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_011181740.1	13	KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_011196928.2	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_011178741.2	56	Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257	"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN"
XP_011191200.2	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_011193312.2	14	Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725	"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_011192750.2	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054087030.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_028896574.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_011194958.2	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_054084333.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_011177094.1	12	KEGG: 05165+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Activation of AMPK downstream of NMDARs";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"TP53 Regulates Metabolic Genes";"Relaxin signaling pathway"
XP_011187103.1	11	Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-5689880	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Ub-specific processing proteases"
XP_054085722.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_011195459.1	6	MetaCyc: PWY-7234;MetaCyc: PWY-6124;KEGG: 00230+3.5.4.10+2.1.2.3;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123	"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I"
XP_028902180.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011189824.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_011178588.1	57	Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257	"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Degradation of AXIN"
XP_011178521.2	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_011194739.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_011182336.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_011190933.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054092039.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_011178281.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_011178831.1	15	MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-6886;Reactome: R-HSA-70171;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6142;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-7003	"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Glycerol degradation to butanol"
XP_054091495.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_054088441.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054086848.1	8	KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;Reactome: R-HSA-5173105	"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"O-linked glycosylation"
XP_054091640.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_011185646.2	5	Reactome: R-HSA-4085001;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Sialic acid metabolism";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_011183530.1	9	Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-6798695	"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"MAP2K and MAPK activation";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Neutrophil degranulation"
XP_011188793.2	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_028894928.2	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_011196718.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_054081891.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054092169.1	22	Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000	"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"RAF activation"
XP_028897534.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_011185962.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_011190205.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011182019.2	5	KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3	"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_054086824.1	13	MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series"
XP_028899786.2	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_054082732.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_054085493.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_054086625.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_011177910.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_054082683.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_011190171.2	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_054083666.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_028897863.2	5	Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_054088112.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_011177811.2	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_054082081.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_028893877.2	7	MetaCyc: PWY-7511;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-983168;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565	"Protein ubiquitination";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_011191034.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_011177892.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_011182006.2	4	Reactome: R-HSA-72086;Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-167160	"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_011195239.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011188470.2	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_011193560.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_054091852.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_054088374.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_011187050.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_011196725.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011191198.2	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_011195960.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054089403.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054083298.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_054083053.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_028899615.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054081966.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_054081322.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054091810.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_011188744.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054090953.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_011193063.1	20	KEGG: 00640+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7574;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7338;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;MetaCyc: PWY-7606	"Propanoate metabolism";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)"
XP_011179920.2	14	MetaCyc: PWY-3841;MetaCyc: PWY-1622;MetaCyc: PWY-5497;MetaCyc: PWY-2161;MetaCyc: PWY-3661;KEGG: 00260+2.1.2.1;KEGG: 00680+2.1.2.1;KEGG: 00630+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-2201;MetaCyc: PWY-3661-1;MetaCyc: PWY-181;KEGG: 00670+2.1.2.1;KEGG: 00460+2.1.2.1	"Folate transformations II (plants)";"Formaldehyde assimilation I (serine pathway)";"Purine nucleobases degradation II (anaerobic)";"Folate polyglutamylation";"Glycine betaine degradation I";"Glycine, serine and threonine metabolism";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"Metabolism of folate and pterines";"Folate transformations I";"Glycine betaine degradation II (mammalian)";"Photorespiration ";"One carbon pool by folate";"Cyanoamino acid metabolism"
XP_011180745.2	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054083512.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_054085991.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011192922.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_011195670.1	5	MetaCyc: PWY-5981;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817	"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_011177439.1	4	MetaCyc: PWY-801;KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603	"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine"
XP_054081504.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_028895193.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011186865.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_028896036.1	5	Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-109704;Reactome: R-HSA-5673001	"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K Cascade";"RAF/MAP kinase cascade"
XP_028895199.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054091588.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_054089416.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_011193438.2	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_054086538.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_011192789.1	8	Reactome: R-HSA-2426168;MetaCyc: PWY-7391;MetaCyc: PWY-7524;Reactome: R-HSA-191273;Reactome: R-HSA-1989781;MetaCyc: PWY-922;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34	"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"PPARA activates gene expression";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis"
XP_011189490.1	5	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-983231;Reactome: R-HSA-6807878	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Factors involved in megakaryocyte development and platelet production";"COPI-mediated anterograde transport"
XP_011180969.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_054089171.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-114516	"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation"
XP_054090507.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_011184763.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011187780.1	2	Reactome: R-HSA-5576886;Reactome: R-HSA-1299308	"Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)"
XP_011182867.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_054090899.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_054083366.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011187559.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054090986.1	15	Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593	"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity"
XP_011194829.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_011191983.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_011186687.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_028900211.2	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_054086126.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_011191542.1	3	KEGG: 00230+3.6.1.17;KEGG: 00240+3.6.1.17;Reactome: R-HSA-3299685	"Purine metabolism";"Pyrimidine metabolism";"Detoxification of Reactive Oxygen Species"
XP_011192053.1	5	MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5667	"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I"
XP_011182273.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7036	"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II"
XP_028894963.1	7	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-373753	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Nephrin family interactions"
XP_054084497.1	14	MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587	"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)"
XP_011187586.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_054090959.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_011184005.2	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_054082560.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_011190041.2	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_054091228.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054082327.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054083808.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_011183941.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054081459.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_054088488.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054083547.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_011191143.2	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_054091831.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011193479.2	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_011178357.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_011187109.3	2	Reactome: R-HSA-72764;Reactome: R-HSA-156581	"Eukaryotic Translation Termination";"Methylation"
XP_054086579.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_028898999.2	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_011184593.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054081201.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_011194271.1	3	Reactome: R-HSA-5619078;Reactome: R-HSA-727802;Reactome: R-HSA-6787639	"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"Transport of nucleotide sugars";"GDP-fucose biosynthesis"
XP_011194365.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_011197147.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_028896440.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_054091465.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway"
XP_011196999.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_054081622.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_011179577.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_054091215.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_054081737.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_011180334.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_028899369.2	17	KEGG: 00620+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5789;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-5744;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-6679;Reactome: R-HSA-200425;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-6722	"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propanoate metabolism";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Jadomycin biosynthesis";"Carnitine metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis"
XP_011179330.2	57	Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761	"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_011187393.2	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_054081572.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-6804760;Reactome: R-HSA-2299718	"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes"
XP_011178912.2	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_011189403.1	4	MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+2.5.1.61	"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_011177670.1	3	MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_011194502.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_054091896.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_011190953.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_011182155.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054082392.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-392154;KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983	"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Arginine and proline metabolism";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)"
XP_011194246.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054090394.1	6	Reactome: R-HSA-5099900;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-114516	"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation"
YP_004891172.1	7	KEGG: 00190+7.1.1.2;Reactome: R-HSA-6799198;MetaCyc: PWY-6692;Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-4302;MetaCyc: PWY-5083	"Oxidative phosphorylation";"Complex I biogenesis";"Fe(II) oxidation";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"NAD/NADH phosphorylation and dephosphorylation"
XP_028901376.1	12	Reactome: R-HSA-1169408;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-450408;Reactome: R-HSA-975956;Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72662;Reactome: R-HSA-9010553	"ISG15 antiviral mechanism";"mTORC1-mediated signalling";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Regulation of expression of SLITs and ROBOs"
XP_054091463.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364	"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_028900283.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011180261.2	11	Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_011179937.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_054088284.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011186017.2	4	Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320	"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation"
XP_011178851.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054088873.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_011179081.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_054087553.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_011177571.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_054088060.1	12	Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-399719	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Long-term potentiation";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors"
XP_054092086.1	9	MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism"
XP_054092165.1	5	Reactome: R-HSA-381038;Reactome: R-HSA-5358346;MetaCyc: PWY-7511;Reactome: R-HSA-5362768;Reactome: R-HSA-901032	"XBP1(S) activates chaperone genes";"Hedgehog ligand biogenesis";"Protein ubiquitination";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER Quality Control Compartment (ERQC)"
XP_028895917.2	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_011188968.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_011185991.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054091213.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_011195811.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011185576.1	4	KEGG: 00510+2.4.1.257+2.4.1.132;KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_011180256.2	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_011190076.2	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_054082238.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011177889.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_054086387.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_011195757.1	5	MetaCyc: PWY-7282;Reactome: R-HSA-964975;Reactome: R-HSA-6798695;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7204	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Neutrophil degranulation";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_054082186.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_028894874.2	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_011189137.2	15	Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-111465;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-3769402;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333;Reactome: R-HSA-5358751;Reactome: R-HSA-5689896	"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Apoptotic cleavage of cellular proteins";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated";"S45 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases"
XP_054084659.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011182275.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_028895871.2	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_011195952.1	7	MetaCyc: PWY-6605;KEGG: 00230+2.4.2.7;MetaCyc: PWY-6610;Reactome: R-HSA-6798695;MetaCyc: PWY-7805;MetaCyc: PWY-7807;Reactome: R-HSA-74217	"Adenine and adenosine salvage II";"Purine metabolism";"Adenine salvage";"Neutrophil degranulation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Purine salvage"
XP_011182937.1	10	MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1042	"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)"
XP_011178576.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054086260.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_011184003.2	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_011180839.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011194615.2	9	Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-400253	"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"Circadian Clock"
XP_054091481.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_011181847.2	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_011182434.1	5	KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.10	"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_011196723.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011181508.2	6	Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616	"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_011178448.1	11	MetaCyc: PWY-6963;MetaCyc: PWY-381;Reactome: R-HSA-210455;MetaCyc: PWY-6964;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675;Reactome: R-HSA-8964539	"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle II";"Nitrogen metabolism";"L-glutamine biosynthesis III";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)";"Glutamate and glutamine metabolism"
XP_011194381.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_011187440.2	13	Reactome: R-HSA-2022090;Reactome: R-HSA-3000157;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-216083;Reactome: R-HSA-186797;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-3000171;Reactome: R-HSA-1474244;Reactome: R-HSA-3000178;Reactome: R-HSA-419037	"Assembly of collagen fibrils and other multimeric structures";"Laminin interactions";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Integrin cell surface interactions";"Signaling by PDGF";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Non-integrin membrane-ECM interactions";"Extracellular matrix organization";"ECM proteoglycans";"NCAM1 interactions"
XP_054088221.1	13	MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2;KEGG: 00720+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-561;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-5913;MetaCyc: PWY-7384	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_011182596.2	9	Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-3645790;Reactome: R-HSA-5689603;Reactome: R-HSA-3642279;Reactome: R-HSA-3656535;Reactome: R-HSA-2173789;Reactome: R-HSA-2173791;Reactome: R-HSA-3304356	"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR2 Kinase Domain Mutants in Cancer";"UCH proteinases";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_011192303.2	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_054083055.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_028901676.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054089405.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_011180675.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_011196787.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011180743.2	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_011195688.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054090895.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_054082692.1	56	Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113	"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1"
XP_011187555.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_011177233.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_011187954.2	6	Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171	"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Collagen degradation";"Non-integrin membrane-ECM interactions"
XP_028895195.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054091194.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_011180046.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011195023.1	2	Reactome: R-HSA-1663150;Reactome: R-HSA-1660662	"The activation of arylsulfatases";"Glycosphingolipid metabolism"
XP_011188378.2	5	Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_028895360.2	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_011190507.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_011182024.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_054088442.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054091219.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_011192997.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_011190848.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_011178608.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-5617472;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580	"Regulation of PTEN gene transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PRC2 methylates histones and DNA";"HCMV Early Events";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence"
XP_011183366.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_011178832.1	7	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-8957275;Reactome: R-HSA-418594;Reactome: R-HSA-114608;Reactome: R-HSA-381426;Reactome: R-HSA-140837	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"Post-translational protein phosphorylation";"G alpha (i) signalling events";"Platelet degranulation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Intrinsic Pathway of Fibrin Clot Formation"
XP_054086623.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_054085495.1	7	KEGG: 00730+3.6.1.15;MetaCyc: PWY-6545;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7198;MetaCyc: PWY-7185;MetaCyc: PWY-7184	"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_011187843.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_028899319.1	4	MetaCyc: PWY-6829;MetaCyc: PWY-7285;Reactome: R-HSA-6782861;MetaCyc: PWY-7286	"Trna methylation (yeast)";"Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_054091469.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_028896699.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_028897974.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054089844.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_011188421.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_011182560.1	6	KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004	"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I"
XP_028897623.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011178123.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054082884.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_011177480.2	2	Reactome: R-HSA-2564830;Reactome: R-HSA-5693554	"Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_054082685.1	5	MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-6121;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_054082577.1	6	Reactome: R-HSA-5673001;Reactome: R-HSA-5654706;Reactome: R-HSA-5654700;Reactome: R-HSA-5654712;Reactome: R-HSA-5654693;Reactome: R-HSA-9028731	"RAF/MAP kinase cascade";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR1 signaling";"Activated NTRK2 signals through FRS2 and FRS3"
XP_054091542.1	19	Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952	"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions"
XP_054087586.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_011190959.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_011187733.2	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_054087907.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_011185832.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054085721.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_011185727.2	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_011191820.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011189300.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_054084004.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_054083788.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011179856.2	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_011187901.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054086975.1	10	Reactome: R-HSA-6798695;Reactome: R-HSA-201688;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-8934903;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853	"Neutrophil degranulation";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Synthesis of PC";"Signal transduction by L1";"Receptor Mediated Mitophagy";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes"
XP_011179617.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054085730.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_011189204.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_054082388.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_028894678.2	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_011177069.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011181407.1	12	Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167243	"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery"
XP_028896345.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054086619.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_028899364.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054091223.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_028895927.2	5	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)"
XP_011189457.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-77289	"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation"
XP_011191199.2	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_011178727.2	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_054089272.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011191148.2	8	Reactome: R-HSA-165054;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"Rev-mediated nuclear export of HIV RNA";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_054086446.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_011177479.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_054082811.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054085316.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011177028.1	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_011177275.2	1	Reactome: R-HSA-376172	"DSCAM interactions"
XP_011188874.2	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054081180.1	29	Reactome: R-HSA-3371453;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5651801;Reactome: R-HSA-68962;Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-5358606;Reactome: R-HSA-6783310;Reactome: R-HSA-3371511;Reactome: R-HSA-5685938;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565	"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of the pre-replicative complex";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Fanconi Anemia Pathway";"HSF1 activation";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Meiotic recombination";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_011188833.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011188283.2	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_011196706.1	13	MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7198	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_011193830.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_011181822.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011176903.2	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_011182018.2	5	Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione metabolism"
XP_011188046.2	13	KEGG: 00720+6.3.4.3;MetaCyc: PWY-2161;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-7909;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-5030;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;Reactome: R-HSA-196757	"Carbon fixation pathways in prokaryotes";"Folate polyglutamylation";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Folate transformations I";"Metabolism of folate and pterines"
XP_054092168.1	22	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins"
XP_011192244.2	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_054084236.1	6	MetaCyc: PWY-7290;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122	"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis"
XP_011185761.2	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_011184040.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054087734.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011181590.2	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_011191144.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_054084607.1	10	KEGG: 00332+2.7.2.11+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00330+2.7.2.11;KEGG: 00332+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41	"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis"
XP_054089648.1	6	MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;MetaCyc: PWY-622;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_054089699.1	10	Reactome: R-HSA-1855191;MetaCyc: PWY-6361;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6372;MetaCyc: PWY-6369;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;MetaCyc: PWY-6362	"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_054088461.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_028898156.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_011192357.2	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_011183604.1	3	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism"
XP_011180217.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_028895961.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_028898998.2	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_011180467.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011184764.2	4	MetaCyc: PWY-6517;MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210	"N-acetylglucosamine degradation II";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_011189682.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition"
XP_054086578.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_011180929.2	14	Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167238	"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation"
XP_054081777.1	4	Reactome: R-HSA-1660662;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119	"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_054083809.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_011187290.1	13	MetaCyc: PWY-7384;MetaCyc: PWY-5913;MetaCyc: PWY-7254;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-561;KEGG: 00020+4.2.1.2;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00720+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism"
XP_054088489.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011179883.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054091229.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054091556.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_054084714.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_011192803.1	10	MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;Reactome: R-HSA-1483166	"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA"
XP_028900378.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054083597.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_011184358.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_011187251.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054083058.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_054084447.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_011194042.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-390471;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation"
XP_011181347.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490	"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins"
XP_054089393.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_054091917.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_011186056.2	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_011189555.2	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
XP_011185651.2	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_054083816.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054090898.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_011180968.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_054088924.1	6	MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism"
XP_054088963.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011188411.2	12	Reactome: R-HSA-73817;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6277;Reactome: R-HSA-196780;MetaCyc: PWY-6122;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6121;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6613;KEGG: 00670+2.1.2.2	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Biotin transport and metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate"
XP_054091589.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_011185445.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_054086539.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_011190553.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054088456.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_011189440.1	7	Reactome: R-HSA-73817;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6277	"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_011181940.2	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_011191195.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_011179235.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011196686.2	13	MetaCyc: PWY-6859;MetaCyc: PWY-7709;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7721;MetaCyc: PWY-7410;MetaCyc: PWY-5123;MetaCyc: PWY-7102;MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-5122;MetaCyc: PWY-7659;MetaCyc: PWY-6383;MetaCyc: PWY-7182	"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Methyl phomopsenoate biosynthesis";"Ipsdienol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Geranyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Linalool biosynthesis I"
XP_011183114.1	5	KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.68	"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis"
XP_011181731.2	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_054085294.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_011197020.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054089395.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_028896349.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_011179977.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011194452.2	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_054086814.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054088965.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011178316.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_011180799.2	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_011194067.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_011196659.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011190426.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_054081647.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054082239.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011186574.2	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_054081350.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_011182321.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_011196715.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_054083947.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_028893631.2	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_054090047.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_011193154.2	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_011187022.1	27	Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-159236;Reactome: R-HSA-111367;Reactome: R-HSA-159227;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-191859;Reactome: R-HSA-6807505;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72203;Reactome: R-HSA-112382;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-674695;Reactome: R-HSA-77588;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-8851708;Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-6803529	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SLBP independent Processing of Histone Pre-mRNAs";"Transport of the SLBP independent Mature mRNA";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"snRNP Assembly";"RNA polymerase II transcribes snRNA genes";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of RNA Pol II elongation complex";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Pre-transcription Events";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Signaling by FGFR2 IIIa TM";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"FGFR2 alternative splicing"
XP_028901509.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_054083282.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_028895281.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_011192912.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_011191223.1	6	Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960	"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC"
XP_054090586.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_011180569.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_011183640.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054091988.1	10	KEGG: 05170+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 05163+2.7.1.153;KEGG: 05165+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 04150+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 04151+2.7.1.153;KEGG: 00562+2.7.1.153;MetaCyc: PWY-6352	"Human immunodeficiency virus 1 infection";"Phosphatidylinositol signaling system";"Human cytomegalovirus infection";"Human papillomavirus infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"mTOR signaling pathway";"Synthesis of PIPs at the plasma membrane";"PI3K-Akt signaling pathway";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis"
XP_054084072.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_011183936.2	4	KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_054087882.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_011191002.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation"
XP_054083742.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011195438.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_011183299.1	24	Reactome: R-HSA-202040;Reactome: R-HSA-418217;Reactome: R-HSA-163359;Reactome: R-HSA-381676;Reactome: R-HSA-6814122;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-400042;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-8964616;Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-456926;Reactome: R-HSA-8964315;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-432040;Reactome: R-HSA-392851	"G-protein activation";"G beta:gamma signalling through PLC beta";"Glucagon signaling in metabolic regulation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through BTK";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor"
XP_011180515.2	7	Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300	"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"G0 and Early G1";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_011193025.2	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_054091592.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_011185609.1	10	Reactome: R-HSA-5684264;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-1169091	"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Downstream TCR signaling";"Activation of NF-kappaB in B cells"
XP_011194974.1	22	MetaCyc: PWY-7726;MetaCyc: PWY-6958;MetaCyc: PWY-5353;MetaCyc: PWY-7049;MetaCyc: PWY-7606;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7592;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+4.2.1.134;MetaCyc: PWY-8041;MetaCyc: PWY-7053;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7728;MetaCyc: PWY-7035;MetaCyc: PWY-7727	"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)"
XP_011184447.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_011192742.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_011191917.1	4	Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_011187216.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_011180563.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011192007.1	3	KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753;MetaCyc: PWY-5686	"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I"
XP_054089954.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_011191556.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012	"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_054082402.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_011183597.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_011186011.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_011176676.2	11	KEGG: 00500+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7184;KEGG: 00770+3.6.1.9;KEGG: 00240+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7821;MetaCyc: PWY-7187	"Starch and sucrose metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pantothenate and CoA biosynthesis";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_011178792.2	10	KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11	"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway"
XP_054082014.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054091468.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_054085445.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_011191589.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011179107.1	12	Reactome: R-HSA-71240;KEGG: 00380+2.6.1.7;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6309;MetaCyc: PWY-801;MetaCyc: PWY-2821;MetaCyc: PWY-6936;MetaCyc: PWY-7901;MetaCyc: PWY-1187;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-601	"Tryptophan catabolism";"Tryptophan metabolism";"Selenocompound metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from homomethionine";"Cysteine and methionine metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tryptophan"
XP_011180284.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_028901636.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_054083717.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_054081566.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_054086116.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_011179621.2	9	Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-69017;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-1362277	"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Transcription of E2F targets under negative control by DREAM complex"
XP_028893610.2	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_011196386.2	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_054088492.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011191712.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
YP_004891166.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054086471.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_011192304.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-8876725	"Respiratory electron transport";"Protein methylation"
XP_028895810.2	33	Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-4570464;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-170822	"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"SUMOylation of RNA binding proteins";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
XP_011190849.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_054091218.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_054091144.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_011176951.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_011182367.2	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_011188379.2	5	Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_028894288.2	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_011182087.2	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_028896416.1	3	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis"
XP_011195473.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_011182740.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011183672.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764	"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination"
XP_054082642.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_011178988.3	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_011195689.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011189780.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054085605.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_028896343.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_028899707.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011185562.1	7	Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.3;MetaCyc: PWY-6614;Reactome: R-HSA-1474151;Reactome: R-HSA-69205	"Metabolism of folate and pterines";"Folate biosynthesis";"Folate transformations II (plants)";"One carbon pool by folate";"Tetrahydrofolate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"G1/S-Specific Transcription"
XP_054083604.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_011196297.1	4	Reactome: R-HSA-1268020;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial protein import";"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054083805.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_054081650.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_011176891.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_011183741.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_054083038.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_054089166.1	6	Reactome: R-HSA-76005;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597	"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"G alpha (z) signalling events"
XP_054086907.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054085080.1	52	Reactome: R-HSA-1834949;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-73980;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-76066;Reactome: R-HSA-5250924;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-5617472;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-72203;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-5578749;Reactome: R-HSA-76071;Reactome: R-HSA-72163;Reactome: R-HSA-113418;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-6782135;Reactome: R-HSA-72165;Reactome: R-HSA-5601884;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-73772	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"B-WICH complex positively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"mRNA Capping";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"mRNA Splicing - Major Pathway";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Dual incision in TC-NER";"mRNA Splicing - Minor Pathway";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape"
XP_054091603.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054089271.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011193486.2	5	Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20;Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20;Reactome: R-HSA-1482883	"Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis";"Neutrophil degranulation";"Glycerolipid metabolism";"Acyl chain remodeling of DAG and TAG"
XP_054085360.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054087575.1	14	KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-8055	"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis"
XP_011195407.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_054088654.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6807505	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes"
XP_011185988.1	5	Reactome: R-HSA-389661;MetaCyc: PWY-6853;Reactome: R-HSA-70688;KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88	"Glyoxylate metabolism and glycine degradation";"Ethylene biosynthesis II (microbes)";"Proline catabolism";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism"
XP_011195817.3	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_028896368.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054089085.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_011179049.1	18	Reactome: R-HSA-70268;Reactome: R-HSA-71064;KEGG: 00260+1.8.1.4;Reactome: R-HSA-204174;KEGG: 00020+1.8.1.4;Reactome: R-HSA-5362517;MetaCyc: PWY-5046;MetaCyc: PWY-5084;KEGG: 00010+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00380+1.8.1.4;Reactome: R-HSA-71403;Reactome: R-HSA-70895;Reactome: R-HSA-6783984;Reactome: R-HSA-389661;KEGG: 00620+1.8.1.4;KEGG: 00640+1.8.1.4;KEGG: 00280+1.8.1.4	"Pyruvate metabolism";"Lysine catabolism";"Glycine, serine and threonine metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glycolysis / Gluconeogenesis";"Lysine degradation";"Tryptophan metabolism";"Citric acid cycle (TCA cycle)";"Branched-chain amino acid catabolism";"Glycine degradation";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Propanoate metabolism";"Valine, leucine and isoleucine degradation"
XP_054083265.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_054088855.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011192198.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_054090628.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_011180769.2	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7035	"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis"
XP_011192149.1	6	Reactome: R-HSA-9603798;Reactome: R-HSA-390247;Reactome: R-HSA-2046105;Reactome: R-HSA-5684045;Reactome: R-HSA-1369062;Reactome: R-HSA-2046106	"Class I peroxisomal membrane protein import";"Beta-oxidation of very long chain fatty acids";"Linoleic acid (LA) metabolism";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"ABC transporters in lipid homeostasis";"alpha-linolenic acid (ALA) metabolism"
XP_011190606.1	4	KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558	"Cysteine and methionine metabolism";"Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine"
XP_011177095.2	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054084375.1	3	Reactome: R-HSA-5635838;Reactome: R-HSA-525793;Reactome: R-HSA-5632681	"Activation of SMO";"Myogenesis";"Ligand-receptor interactions"
XP_011178530.2	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_011196879.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-168333	"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_054091128.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_028899773.2	8	Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-5689880;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes"
XP_011190574.2	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054087623.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054087664.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_011185074.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054087865.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_054084798.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011188886.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011186555.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_011190420.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_011177636.2	5	Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841	"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines"
XP_054090979.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_011183406.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_011179341.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054088787.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_011194343.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011184461.2	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_011182557.1	6	KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11	"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism"
XP_054088543.1	4	Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_011180548.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_011176708.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054082812.1	7	Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948	"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_011181186.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_054090814.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011181946.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_011177454.2	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Cyanoamino acid metabolism"
XP_011184518.1	3	Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23	"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism"
XP_054087329.1	6	Reactome: R-HSA-73817;MetaCyc: PWY-7234;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6123;KEGG: 00230+4.1.1.21;MetaCyc: PWY-6124	"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II"
XP_054088723.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_028897408.1	3	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_011180111.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_028896104.1	12	Reactome: R-HSA-193692;Reactome: R-HSA-75893;Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-1251985;Reactome: R-HSA-5362798;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-982772	"Regulated proteolysis of p75NTR";"TNF signaling";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"Nuclear signaling by ERBB4";"Release of Hh-Np from the secreting cell";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Growth hormone receptor signaling"
XP_054081817.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_054091562.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054089887.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_054088057.1	12	Reactome: R-HSA-451308;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-447038	"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions"
XP_054087410.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011192194.2	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054090328.1	5	MetaCyc: PWY-7159;MetaCyc: PWY-7766;Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37;MetaCyc: PWY-5531	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)"
XP_011189786.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_054085561.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_011182540.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011181692.2	42	MetaCyc: PWY-7216;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6945;MetaCyc: PWY-7654;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-7094;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6946;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6944;KEGG: 00903+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7401;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-5109;MetaCyc: PWY-6583;MetaCyc: PWY-7779;MetaCyc: PWY-6435;MetaCyc: PWY-1361;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;KEGG: 00360+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-7726;MetaCyc: PWY-6883;MetaCyc: PWY-5177;MetaCyc: PWY-7656;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606	"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Lysine degradation";"Pyruvate fermentation to hexanol (engineered)";"beta-Alanine metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Valine, leucine and isoleucine degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Caprolactam degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid salvage";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Benzoate degradation";"Toluene degradation";"Aminobenzoate degradation";"Androstenedione degradation";"Limonene and pinene degradation";"Fatty acid elongation";"Butanoate metabolism";"Propanoate metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Geraniol degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Fermentation to 2-methylbutanoate";"Pyruvate fermentation to butanol I";"Methyl tert-butyl ether degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Benzoyl-coa degradation I (aerobic)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Phenylalanine metabolism";"Tryptophan metabolism";"2-methylpropene degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Pyruvate fermentation to butanol II (engineered)";"Glutaryl-coa degradation";"Spodoptera littoralis pheromone biosynthesis";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)"
XP_054083570.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_054081790.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011180476.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_011178677.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_028902134.1	13	Reactome: R-HSA-8876725;Reactome: R-HSA-5362768;Reactome: R-HSA-5689877;Reactome: R-HSA-110320;Reactome: R-HSA-8866654;Reactome: R-HSA-5689896;Reactome: R-HSA-532668;Reactome: R-HSA-9646399;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-3371511;Reactome: R-HSA-382556;Reactome: R-HSA-6798695	"Protein methylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Josephin domain DUBs";"Translesion Synthesis by POLH";"E3 ubiquitin ligases ubiquitinate target proteins";"Ovarian tumor domain proteases";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Aggrephagy";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"HSF1 activation";"ABC-family proteins mediated transport";"Neutrophil degranulation"
XP_011186382.2	5	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation"
XP_028895962.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011186300.2	56	Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091	"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Activation of NF-kappaB in B cells"
XP_011184230.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054088354.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_054085660.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054086644.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054091498.1	6	MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_011182746.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_011187070.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054084523.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_011185762.2	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054083860.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_028897735.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_011180090.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_011182526.1	5	Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-109704;Reactome: R-HSA-5673001	"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K Cascade";"RAF/MAP kinase cascade"
XP_054085750.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_011178193.2	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_011179138.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_011195566.1	13	KEGG: 00720+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5132;MetaCyc: PWY-5108;KEGG: 00620+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5133;Reactome: R-HSA-71384;KEGG: 00010+6.2.1.1;MetaCyc: PWY-6672	"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol";"Lupulone and humulone biosynthesis";"L-isoleucine biosynthesis V";"Pyruvate metabolism";"Propanoate metabolism";"Glyoxylate and dicarboxylate metabolism";"Adlupulone and adhumulone biosynthesis";"Methane metabolism";"Colupulone and cohumulone biosynthesis";"Ethanol oxidation";"Glycolysis / Gluconeogenesis";"Cis-genanyl-coa degradation"
XP_011196060.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7417	"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)"
XP_011193322.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054089755.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_028897050.2	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_011192983.2	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_028896939.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011181234.1	25	Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-416482;Reactome: R-HSA-8964315;Reactome: R-HSA-456926;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-9009391;Reactome: R-HSA-381771;Reactome: R-HSA-428930;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-8964616;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-400042;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-6814122;Reactome: R-HSA-381676;Reactome: R-HSA-163359;Reactome: R-HSA-418217;Reactome: R-HSA-202040	"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"G alpha (12/13) signalling events";"G beta:gamma signalling through BTK";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"Extra-nuclear estrogen signaling";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Thromboxane signalling through TP receptor";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through PLC beta";"G-protein activation"
XP_011179286.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_054082255.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011186196.2	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_011184514.2	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_011185511.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_011188725.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_011187618.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_054087939.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054091609.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011184679.1	18	KEGG: 00983+2.4.2.3;MetaCyc: PWY-5695;Reactome: R-HSA-73621;MetaCyc: PWY-6620;KEGG: 00240+2.4.2.3;MetaCyc: PWY-6608;MetaCyc: PWY-4202;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179;Reactome: R-HSA-73614;MetaCyc: PWY-6609;MetaCyc: PWY-6611;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179-1;MetaCyc: PWY-6644;MetaCyc: PWY-6627;KEGG: 00760+2.4.2.1;MetaCyc: PWY-5532	"Drug metabolism - other enzymes";"Inosine 5'-phosphate degradation";"Pyrimidine catabolism";"Guanine and guanosine salvage";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Pyrimidine salvage";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Fluoroacetate and fluorothreonine biosynthesis";"Salinosporamide A biosynthesis";"Nicotinate and nicotinamide metabolism";"Nucleoside and nucleotide degradation (archaea)"
XP_054085556.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_011195760.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_011181867.2	6	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-8939211;Reactome: R-HSA-5693565;Reactome: R-HSA-5675221	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"ESR-mediated signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Negative regulation of MAPK pathway"
XP_011194232.1	7	Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00620+2.3.1.12;KEGG: 00020+2.3.1.12;Reactome: R-HSA-70268;KEGG: 00010+2.3.1.12	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_011178468.1	5	Reactome: R-HSA-197264;Reactome: R-HSA-1368108;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381	"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_011187252.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054089753.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_011181028.1	22	Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-5358752;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-389513;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337	"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CTLA4 inhibitory signaling";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding"
XP_011194076.1	10	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04151+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04926+2.7.11.1;Reactome: R-HSA-437239	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"RSK activation";"PI3K-Akt signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Relaxin signaling pathway";"Recycling pathway of L1"
XP_011180719.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054082557.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_054087318.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_054088999.1	7	Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921	"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation"
XP_011194773.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762	"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_054088886.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_054083406.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054082098.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_011180500.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_011180582.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_011193836.2	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_011188723.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_011180601.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_011197008.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054083269.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_011187329.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_054091294.1	14	MetaCyc: PWY-7036;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725	"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_011188900.1	56	Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Separation of Sister Chromatids"
XP_011192567.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011195940.2	9	Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6804756	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation"
XP_011176830.2	8	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083633	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_011177312.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011193401.1	20	Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-69091	"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching"
XP_028898795.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_011185002.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_011190027.2	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_011196421.2	29	Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-6796648	"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes"
XP_028899266.2	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_011178287.1	9	MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-5744	"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation"
XP_028896980.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946	"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin"
XP_011189085.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_054082341.1	13	Reactome: R-HSA-2022090;Reactome: R-HSA-3000157;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-216083;Reactome: R-HSA-1650814;Reactome: R-HSA-186797;Reactome: R-HSA-2243919;Reactome: R-HSA-3000171;Reactome: R-HSA-2214320;Reactome: R-HSA-1474244;Reactome: R-HSA-3000178;Reactome: R-HSA-419037	"Assembly of collagen fibrils and other multimeric structures";"Laminin interactions";"Collagen chain trimerization";"Collagen degradation";"Integrin cell surface interactions";"Collagen biosynthesis and modifying enzymes";"Signaling by PDGF";"Crosslinking of collagen fibrils";"Non-integrin membrane-ECM interactions";"Anchoring fibril formation";"Extracellular matrix organization";"ECM proteoglycans";"NCAM1 interactions"
XP_011187108.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_011186344.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_054083646.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-9020702	"Neutrophil degranulation";"Interleukin-1 signaling"
XP_011187974.2	4	KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing"
XP_054087881.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054083741.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054086774.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_054084071.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_011189868.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054083930.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011190938.1	4	Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-982772	"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Growth hormone receptor signaling"
XP_011192810.2	5	KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3	"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)"
XP_011185583.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758	"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation"
XP_054089825.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_054091305.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_028895304.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_011187623.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_011182966.2	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_054090975.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054082173.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_054086208.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011178414.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_054090533.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_011178080.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_028895200.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_011187021.1	27	Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-6803529;Reactome: R-HSA-73856;Reactome: R-HSA-8851708;Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-159231;Reactome: R-HSA-72203;Reactome: R-HSA-77595;Reactome: R-HSA-112382;Reactome: R-HSA-77588;Reactome: R-HSA-674695;Reactome: R-HSA-159230;Reactome: R-HSA-9010553;Reactome: R-HSA-191859;Reactome: R-HSA-6807505;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-72163;Reactome: R-HSA-159227;Reactome: R-HSA-111367;Reactome: R-HSA-159236;Reactome: R-HSA-167242	"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Termination";"Signaling by FGFR2 IIIa TM";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Capped Intron-Containing Pre-mRNA";"Processing of Intronless Pre-mRNAs";"Formation of RNA Pol II elongation complex";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Pre-transcription Events";"Transport of the SLBP Dependant Mature mRNA";"Regulation of expression of SLITs and ROBOs";"snRNP Assembly";"RNA polymerase II transcribes snRNA genes";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Major Pathway";"Transport of the SLBP independent Mature mRNA";"SLBP independent Processing of Histone Pre-mRNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_011192797.2	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_011178360.1	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS I - Hurler syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_011188436.1	17	Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-6791226	"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_011187813.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_028900222.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_011178917.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_011177760.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_011194507.2	9	KEGG: 00564+1.1.1.8;MetaCyc: PWY-7385;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-6118;MetaCyc: PWY-7902;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7411	"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle";"Glucosylglycerol biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)"
XP_011176977.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011181705.1	7	Reactome: R-HSA-381070;Reactome: R-HSA-381042;Reactome: R-HSA-381183;Reactome: R-HSA-114608;Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-3371453	"IRE1alpha activates chaperones";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of HSF1-mediated heat shock response"
XP_054088167.1	3	Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_011189446.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_011191857.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054086849.1	13	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-3928663;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5627117	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"EPHB-mediated forward signaling";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Sema4D induced cell migration and growth-cone collapse";"EPHA-mediated growth cone collapse";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"G alpha (12/13) signalling events";"Human papillomavirus infection";"Thermogenesis";"RHO GTPases Activate ROCKs"
XP_011183896.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054088491.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054091591.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_054082401.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_011177566.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_011178712.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_011179376.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition"
XP_054085592.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_028900500.2	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
XP_054083911.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_011181766.2	2	Reactome: R-HSA-500753;Reactome: R-HSA-73621	"Pyrimidine biosynthesis";"Pyrimidine catabolism"
XP_011178268.2	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_011185561.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054089681.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_011190061.2	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_054082540.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_028896070.2	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_011191124.2	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_011188549.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011193909.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_028898484.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_054089220.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_028895576.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054081611.1	12	Reactome: R-HSA-9013508;Reactome: R-HSA-350054;Reactome: R-HSA-9013695;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947	"NOTCH3 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_028898052.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_011196217.2	11	Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-163359	"G alpha (s) signalling events";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation"
XP_054082286.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_011176478.1	22	Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"RAF activation";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_011190624.2	9	Reactome: R-HSA-69205;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-176187	"G1/S-Specific Transcription";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_054087573.1	14	KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-5667;MetaCyc: PWY-8053	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II"
XP_011179255.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1"
XP_011187084.1	27	Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-159236	"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"snRNP Assembly";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_028902045.2	6	KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7290	"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_011189132.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381038;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_011181751.2	2	KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105	"Fatty acid elongation";"Fatty acyl-CoA biosynthesis"
XP_054091605.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_011184743.1	4	Reactome: R-HSA-1237112;MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23	"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism"
XP_028898929.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_011186348.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011188250.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_011184122.2	8	KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Activation of RAC1";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_028894601.1	5	MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;Reactome: R-HSA-197264	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging"
XP_054083584.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_011186399.2	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_011176952.1	4	KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004	"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Entner-Doudoroff pathway I"
XP_054081709.1	5	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.10;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
XP_054092079.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_054084880.1	3	KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_011184046.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
XP_054084638.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011178561.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054082641.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_011181596.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011187067.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_028896534.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_011193557.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_054086160.1	9	Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783	"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type"
XP_011187978.1	4	KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32	"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism"
XP_011194687.1	4	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_054085512.1	1	Reactome: R-HSA-3000178	"ECM proteoglycans"
XP_011179520.1	57	Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761	"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_054091193.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_054087649.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_011177685.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_011178711.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054089555.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_011188338.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_011192164.1	3	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"One carbon pool by folate";"Glycine degradation"
XP_011180744.2	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_011183058.2	4	Reactome: R-HSA-111465;Reactome: R-HSA-5693607;Reactome: R-HSA-5689880;Reactome: R-HSA-176187	"Apoptotic cleavage of cellular proteins";"Processing of DNA double-strand break ends";"Ub-specific processing proteases";"Activation of ATR in response to replication stress"
XP_054085550.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054090693.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_011191791.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_011188745.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011188924.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054084436.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054091610.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011194865.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054091039.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_011180060.2	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_028893652.1	22	Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-5358752;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-389513;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000	"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"RAF activation"
XP_011180635.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_011192200.2	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_011182433.1	5	KEGG: 00230+2.7.4.10;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_011188525.1	2	KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399	"Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_011190196.1	3	KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451;MetaCyc: PWY-7159	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_054088261.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054087409.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011177692.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_011188197.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011187734.2	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_011182931.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs"
XP_054092054.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_011196051.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-7782	"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Plasmalogen biosynthesis"
XP_054088749.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_011180793.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"ECM proteoglycans";"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_054083770.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011188211.2	1	Reactome: R-HSA-70171	"Glycolysis"
XP_011186085.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_054088798.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_011189344.1	14	Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-2173788;Reactome: R-HSA-5663220;Reactome: R-HSA-69273;Reactome: R-HSA-5687128;Reactome: R-HSA-450520;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3769402;Reactome: R-HSA-9634638	"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"Downregulation of TGF-beta receptor signaling";"RHO GTPases Activate Formins";"Cyclin A/B1/B2 associated events during G2/M transition";"MAPK6/MAPK4 signaling";"HuR (ELAVL1) binds and stabilizes mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Deactivation of the beta-catenin transactivating complex";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling"
XP_011193889.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011196653.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_011184121.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_028894221.2	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_011177013.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054090399.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-114516	"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation"
XP_054091967.1	12	KEGG: 00010+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;Reactome: R-HSA-70171;KEGG: 00710+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1042;KEGG: 00030+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1861	"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Gluconeogenesis";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_054084026.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_054086825.1	13	KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Anhydromuropeptides recycling II";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_011178245.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_011187844.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054085332.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011181710.1	10	Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-8948751;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-201688	"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"Regulation of PTEN stability and activity";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL"
XP_011187451.2	5	Reactome: R-HSA-5610787;Reactome: R-HSA-373080;Reactome: R-HSA-5620922;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684	"Hedgehog 'off' state";"Class B/2 (Secretin family receptors)";"BBSome-mediated cargo-targeting to cilium";"Activation of SMO";"Hedgehog 'on' state"
XP_054084723.1	4	MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_054084247.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_011184859.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_054087171.1	24	Reactome: R-HSA-163359;Reactome: R-HSA-418217;Reactome: R-HSA-202040;Reactome: R-HSA-418597;Reactome: R-HSA-381676;Reactome: R-HSA-6814122;Reactome: R-HSA-400042;Reactome: R-HSA-420092;Reactome: R-HSA-8964616;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-418555;Reactome: R-HSA-416482;Reactome: R-HSA-8964315;Reactome: R-HSA-456926;Reactome: R-HSA-500657;Reactome: R-HSA-392851;Reactome: R-HSA-432040	"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through PLC beta";"G-protein activation";"G alpha (z) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-type ligand receptors";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"G alpha (s) signalling events";"G alpha (12/13) signalling events";"G beta:gamma signalling through BTK";"Thrombin signalling through proteinase activated receptors (PARs)";"Presynaptic function of Kainate receptors";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_054087266.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011176622.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_028900380.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_011182757.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011181207.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_028901135.2	12	KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783	"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Plasmalogen degradation"
XP_011192576.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_054091214.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_011180136.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_011178309.2	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_054091464.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_028900284.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_011196781.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054082856.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_011195627.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054084598.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_011188141.1	5	MetaCyc: PWY-6749;Reactome: R-HSA-446210;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16	"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_011176737.2	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054088283.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011186755.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_011187779.1	2	Reactome: R-HSA-5576886;Reactome: R-HSA-1299308	"Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)"
XP_011180528.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054090393.1	6	Reactome: R-HSA-114516;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-5099900	"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4"
XP_054089958.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_054088919.1	13	MetaCyc: PWY-7182;MetaCyc: PWY-6383;MetaCyc: PWY-5122;MetaCyc: PWY-7736;MetaCyc: PWY-7659;MetaCyc: PWY-7141;MetaCyc: PWY-7102;MetaCyc: PWY-5123;MetaCyc: PWY-7410;MetaCyc: PWY-7721;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7709;MetaCyc: PWY-6859	"Linalool biosynthesis I";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Geranyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"Viridicatumtoxin biosynthesis";"(3S)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Methyl phomopsenoate biosynthesis";"Terpenoid backbone biosynthesis";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis"
XP_054088046.1	12	Reactome: R-HSA-447038;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-451308	"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor"
XP_011179772.2	3	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054086437.1	3	Reactome: R-HSA-3214815;Reactome: R-HSA-427413;Reactome: R-HSA-390522	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression";"Striated Muscle Contraction"
XP_011177065.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_011197046.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011192168.2	9	Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-975634	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport"
XP_011176508.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054084250.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_011185128.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_028895228.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_054085727.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_011179478.1	24	Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497	"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"RHO GTPases Activate Formins";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Aggrephagy";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_028902064.2	9	Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73779	"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_011192890.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011182068.2	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_011182667.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011192950.2	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_054086246.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054091921.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_011195015.2	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_054083123.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011178730.2	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_054086027.1	11	Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4"
XP_011190501.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054086580.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_011178128.2	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_011193480.2	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_011184184.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_011185001.2	8	KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-8086;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481	"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Propanoate metabolism";"Cysteine and methionine metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate"
XP_011192991.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation"
XP_054086502.1	5	Reactome: R-HSA-211945;Reactome: R-HSA-8937144;Reactome: R-HSA-211976;Reactome: R-HSA-211981;Reactome: R-HSA-1989781	"Phase I - Functionalization of compounds";"Aryl hydrocarbon receptor signalling";"Endogenous sterols";"Xenobiotics";"PPARA activates gene expression"
XP_011179910.1	27	Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-9610379	"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"snRNP Assembly";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events"
XP_011186864.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_028895521.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011191264.2	5	MetaCyc: PWY-7511;Reactome: R-HSA-5362768;Reactome: R-HSA-901032;Reactome: R-HSA-381038;Reactome: R-HSA-5358346	"Protein ubiquitination";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER Quality Control Compartment (ERQC)";"XBP1(S) activates chaperone genes";"Hedgehog ligand biogenesis"
XP_054087643.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_028900096.2	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_054082087.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_011179402.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054081957.1	4	KEGG: 00564+3.1.1.7;Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Glycerophospholipid metabolism";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_011180639.1	13	KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-5538;MetaCyc: PWY-6728	"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle"
XP_054084121.1	9	MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-416476;MetaCyc: PWY-8052	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"PLC beta mediated events";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis"
XP_054083340.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011193910.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_011177751.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Cargo concentration in the ER"
XP_011180484.1	8	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Signaling by Hippo"
XP_011196998.2	13	Reactome: R-HSA-5607763;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-983695;Reactome: R-HSA-5218921;Reactome: R-HSA-381676;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-422356	"CLEC7A (Dectin-1) induces NFAT activation";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"VEGFR2 mediated cell proliferation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"Regulation of insulin secretion"
XP_011191984.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054089907.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_028896451.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054084948.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_054083767.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011181139.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054082740.1	3	Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725	"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation";"Protein methylation"
XP_011178605.2	13	KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Anhydromuropeptides recycling II";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
XP_054089586.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER"
XP_054082023.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_054081710.1	5	KEGG: 00230+2.7.4.10;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism"
XP_054089226.1	83	Reactome: R-HSA-512988;Reactome: R-HSA-5654704;Reactome: R-HSA-5655253;Reactome: R-HSA-5673001;Reactome: R-HSA-5654710;Reactome: R-HSA-9645135;Reactome: R-HSA-5663213;Reactome: R-HSA-9034864;Reactome: R-HSA-1963640;Reactome: R-HSA-8875555;Reactome: R-HSA-5655291;Reactome: R-HSA-9027284;Reactome: R-HSA-180292;Reactome: R-HSA-375165;Reactome: R-HSA-210993;Reactome: R-HSA-9026519;Reactome: R-HSA-1295596;Reactome: R-HSA-5654733;Reactome: R-HSA-112412;Reactome: R-HSA-9028731;Reactome: R-HSA-5654695;Reactome: R-HSA-5654693;Reactome: R-HSA-912526;Reactome: R-HSA-8983432;Reactome: R-HSA-1839117;Reactome: R-HSA-2179392;Reactome: R-HSA-5654699;Reactome: R-HSA-9028335;Reactome: R-HSA-5654720;Reactome: R-HSA-5654719;Reactome: R-HSA-1433559;Reactome: R-HSA-391160;Reactome: R-HSA-8865999;Reactome: R-HSA-5654706;Reactome: R-HSA-8853334;Reactome: R-HSA-912631;Reactome: R-HSA-1250347;Reactome: R-HSA-109704;Reactome: R-HSA-9607240;Reactome: R-HSA-389359;Reactome: R-HSA-1236382;Reactome: R-HSA-186763;Reactome: R-HSA-5654700;Reactome: R-HSA-5654689;Reactome: R-HSA-8851805;Reactome: R-HSA-6807004;Reactome: R-HSA-5655302;Reactome: R-HSA-6811558;Reactome: R-HSA-5654727;Reactome: R-HSA-182971;Reactome: R-HSA-5654726;Reactome: R-HSA-180336;Reactome: R-HSA-1963642;Reactome: R-HSA-9664565;Reactome: R-HSA-5654712;Reactome: R-HSA-8875656;Reactome: R-HSA-2219530;Reactome: R-HSA-5637810;Reactome: R-HSA-354194;Reactome: R-HSA-179812;Reactome: R-HSA-8875360;Reactome: R-HSA-9634285;Reactome: R-HSA-2424491;Reactome: R-HSA-74751;Reactome: R-HSA-5654688;Reactome: R-HSA-8853338;Reactome: R-HSA-2730905;Reactome: R-HSA-8856825;Reactome: R-HSA-983695;Reactome: R-HSA-2029482;Reactome: R-HSA-2428933;Reactome: R-HSA-8856828;Reactome: R-HSA-388841;Reactome: R-HSA-1257604;Reactome: R-HSA-2871796;Reactome: R-HSA-5654732;Reactome: R-HSA-74749;Reactome: R-HSA-1433557;Reactome: R-HSA-2871809;Reactome: R-HSA-1250196;Reactome: R-HSA-8851907;Reactome: R-HSA-8853659;Reactome: R-HSA-167044	"Interleukin-3, Interleukin-5 and GM-CSF signaling";"SHC-mediated cascade:FGFR3";"Signaling by FGFR2 in disease";"RAF/MAP kinase cascade";"PI-3K cascade:FGFR3";"STAT5 Activation";"RHO GTPases Activate WASPs and WAVEs";"Activated NTRK3 signals through RAS";"GRB2 events in ERBB2 signaling";"MET activates RAP1 and RAC1";"Signaling by FGFR4 in disease";"Erythropoietin activates RAS";"GAB1 signalosome";"NCAM signaling for neurite out-growth";"Tie2 Signaling";"Activated NTRK2 signals through RAS";"Spry regulation of FGF signaling";"Negative regulation of FGFR4 signaling";"SOS-mediated signalling";"Activated NTRK2 signals through FRS2 and FRS3";"PI-3K cascade:FGFR2";"FRS-mediated FGFR1 signaling";"Interleukin receptor SHC signaling";"Interleukin-15 signaling";"Signaling by cytosolic FGFR1 fusion mutants";"EGFR Transactivation by Gastrin";"SHC-mediated cascade:FGFR2";"Activated NTRK2 signals through PI3K";"PI-3K cascade:FGFR4";"SHC-mediated cascade:FGFR4";"Regulation of KIT signaling";"Signal regulatory protein family interactions";"MET activates PTPN11";"FRS-mediated FGFR3 signaling";"Signaling by FGFR3 fusions in cancer";"Regulation of signaling by CBL";"SHC1 events in ERBB4 signaling";"PI3K Cascade";"FLT3 Signaling";"CD28 dependent Vav1 pathway";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Downstream signal transduction";"FRS-mediated FGFR2 signaling";"PI-3K cascade:FGFR1";"MET activates RAS signaling";"Negative regulation of MET activity";"Signaling by FGFR1 in disease";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of FGFR2 signaling";"EGFR downregulation";"Negative regulation of FGFR1 signaling";"SHC1 events in EGFR signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"FRS-mediated FGFR4 signaling";"MET receptor recycling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Constitutive Signaling by EGFRvIII";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"GRB2 events in EGFR signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Constitutive Signaling by Overexpressed ERBB2";"DAP12 signaling";"Insulin receptor signalling cascade";"SHC-mediated cascade:FGFR1";"Signaling by FGFR3 point mutants in cancer";"Role of LAT2/NTAL/LAB on calcium mobilization";"Cargo recognition for clathrin-mediated endocytosis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of actin dynamics for phagocytic cup formation";"SHC-related events triggered by IGF1R";"Clathrin-mediated endocytosis";"Costimulation by the CD28 family";"PIP3 activates AKT signaling";"FCERI mediated MAPK activation";"Negative regulation of FGFR3 signaling";"Signal attenuation";"Signaling by SCF-KIT";"FCERI mediated Ca+2 mobilization";"SHC1 events in ERBB2 signaling";"MET activates PI3K/AKT signaling";"RET signaling";"Signalling to RAS"
XP_054090062.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_011196009.2	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_011193811.2	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_011183308.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_011195013.2	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_054089702.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011178761.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_011187266.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_028899933.2	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_054090382.1	10	KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23	"Other glycan degradation";"Galactose metabolism";"HS-GAG degradation";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series"
XP_011177689.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_054082726.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011181650.2	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_028897868.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_054089047.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_011182708.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_011190735.1	9	MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism"
XP_028896773.2	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_011176909.1	4	Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-176187	"Unwinding of DNA";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress"
XP_054082280.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_011177434.1	29	Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135	"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"mRNA Capping";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER"
XP_011189843.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_011192299.2	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_011192936.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_028893556.2	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_011193667.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_011183950.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011180333.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_011194828.2	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_028900031.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011192248.2	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_011192495.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_011186753.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_054088285.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011190012.2	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_011179370.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_028901174.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_054088071.1	8	Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-9609736	"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors"
XP_011178053.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054081662.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_011195330.2	11	MetaCyc: PWY-6992;MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-7456;MetaCyc: PWY-5659;KEGG: 00051+5.3.1.8;MetaCyc: PWY-7586;MetaCyc: PWY-882;MetaCyc: PWY-3861;Reactome: R-HSA-446205	"1,5-anhydrofructose degradation";"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol degradation II";"Synthesis of GDP-mannose"
XP_011181566.2	56	Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-1169091	"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells"
XP_011193235.2	11	Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-674695	"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events"
XP_011186315.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_054085792.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-432722;Reactome: R-HSA-8856825;Reactome: R-HSA-6798695	"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation"
XP_054090395.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-114516	"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation"
XP_054088525.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_011188261.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
XP_011188375.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_011184436.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_011190257.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054087405.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011186471.2	4	Reactome: R-HSA-499943;Reactome: R-HSA-2161541;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_011177063.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_011194538.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_011177822.3	5	MetaCyc: PWY-5381;KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761;MetaCyc: PWY-5653;Reactome: R-HSA-196807	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism"
XP_011185632.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_028893583.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011196441.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054091182.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054091837.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_054086132.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_054087146.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_011189062.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_011183608.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation"
XP_011183282.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054090682.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_054084491.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-168164	"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade"
XP_054083626.1	5	Reactome: R-HSA-197264;Reactome: R-HSA-1368108;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381	"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_011192118.1	4	Reactome: R-HSA-189451;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5189;MetaCyc: PWY-5188	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_054082439.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054084184.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_028897975.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054086823.1	13	KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52	"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation"
XP_028898441.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_028902233.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_011187643.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_011188794.2	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_054082667.1	20	MetaCyc: PWY-7606;MetaCyc: PWY-6920;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-7338;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6	"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism"
XP_011187800.2	3	Reactome: R-HSA-1369062;Reactome: R-HSA-8964058;Reactome: R-HSA-9029569	"ABC transporters in lipid homeostasis";"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_054090036.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011182670.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011180782.1	4	Reactome: R-HSA-499943;KEGG: 00590+5.3.99.3;Reactome: R-HSA-2162123;Reactome: R-HSA-6798695	"Interconversion of nucleotide di- and triphosphates";"Arachidonic acid metabolism";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Neutrophil degranulation"
XP_054081636.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_011176540.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_011177683.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054081503.1	10	Reactome: R-HSA-200425;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354	"Carnitine metabolism";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Lipophagy"
XP_011193107.2	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_054091396.1	9	MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1	"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism"
XP_011186669.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_011187955.2	6	Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-8874081;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090	"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"Collagen degradation";"MET activates PTK2 signaling";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures"
XP_011191310.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011194573.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054091195.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054081207.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_011177842.2	10	Reactome: R-HSA-3899300;Reactome: R-HSA-9615017;Reactome: R-HSA-983231;Reactome: R-HSA-400206;Reactome: R-HSA-9022692;Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-9022699	"SUMOylation of transcription cofactors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Factors involved in megakaryocyte development and platelet production";"Regulation of lipid metabolism by PPARalpha";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates neuronal receptors and channels"
XP_011184057.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_011187554.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_011180519.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011188020.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_011186814.2	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
XP_011180964.1	11	MetaCyc: PWY-5695;MetaCyc: PWY-6538;Reactome: R-HSA-8851680;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6607;MetaCyc: PWY-6608;MetaCyc: PWY-5497;MetaCyc: PWY-6596;MetaCyc: PWY-6606;MetaCyc: PWY-6999;Reactome: R-HSA-74259	"Inosine 5'-phosphate degradation";"Caffeine degradation III (bacteria, via demethylation)";"Butyrophilin (BTN) family interactions";"Purine metabolism";"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Theophylline degradation";"Purine catabolism"
XP_011188906.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_011180923.1	11	MetaCyc: PWY-7560;MetaCyc: PWY-6383;MetaCyc: PWY-922;MetaCyc: PWY-7102;MetaCyc: PWY-6174;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7391;MetaCyc: PWY-7524;Reactome: R-HSA-191273;MetaCyc: PWY-5123;MetaCyc: PWY-6859	"Methylerythritol phosphate pathway II";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Mevalonate pathway I";"Bisabolene biosynthesis (engineered)";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis"
XP_054088928.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_011196003.2	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_054089404.1	3	Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23	"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism"
XP_011179278.2	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_054082952.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_028898706.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011179025.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054090954.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_054088373.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_011184212.1	56	Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-1236978	"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_011195006.2	6	Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176974	"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Unwinding of DNA"
XP_011189958.1	3	Reactome: R-HSA-4085001;MetaCyc: PWY-1269;KEGG: 00540+2.7.7.38	"Sialic acid metabolism";"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Lipopolysaccharide biosynthesis"
XP_054082910.1	10	Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5685942	"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"HDR through Homologous Recombination (HRR)"
XP_011188564.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_011179861.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054088802.1	56	Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-5658442	"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs"
XP_011196943.2	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054088880.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011180633.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054089050.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_054090426.1	9	MetaCyc: PWY-6703;MetaCyc: PWY-7852;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6147;Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-5664;MetaCyc: PWY-5663;MetaCyc: PWY-6983	"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis"
XP_011193134.1	8	KEGG: 04658+3.1.3.16;MetaCyc: PWY-5269;Reactome: R-HSA-1483148;KEGG: 04660+3.1.3.16;MetaCyc: PWY-5668;KEGG: 00564+3.1.3.27;KEGG: 05235+3.1.3.16;MetaCyc: PWY-7817	"Th1 and Th2 cell differentiation";"Cardiolipin biosynthesis II";"Synthesis of PG";"T cell receptor signaling pathway";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_028893756.1	16	Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-174048	"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B"
YP_004891177.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_028897958.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_011190369.1	12	MetaCyc: PWY-6142;KEGG: 00010+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00030+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1042;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00710+4.1.2.13;KEGG: 00051+4.1.2.13	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Gluconeogenesis";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism"
XP_054082397.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054083810.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_054086395.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_011179201.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054088262.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054088450.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_028898270.1	2	Reactome: R-HSA-1299308;Reactome: R-HSA-5576886	"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential"
XP_054091651.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_011185696.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_011177178.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation"
XP_011197004.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054085610.1	8	Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-164378	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"PKA activation in glucagon signalling"
XP_011193862.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_011179508.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054085511.1	1	Reactome: R-HSA-3000178	"ECM proteoglycans"
XP_011196270.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_011189313.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054081867.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_028893789.1	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_054086204.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_011193697.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011188057.2	4	KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193;Reactome: R-HSA-4720454;KEGG: 00513+2.4.1.261	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Various types of N-glycan biosynthesis"
XP_011184675.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011195710.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_011184906.2	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_011196467.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_028897778.2	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_054086300.1	4	Reactome: R-HSA-5661270;KEGG: 00561+2.7.1.30;KEGG: 00040+2.7.1.17;MetaCyc: PWY-4261	"Formation of xylulose-5-phosphate";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Glycerol degradation I"
XP_011182737.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_054086382.1	4	KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193;Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131	"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis"
XP_054087172.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_011181790.2	20	Reactome: R-HSA-6804756;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-69091	"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Polymerase switching"
XP_028898639.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054081153.1	19	Reactome: R-HSA-381426;Reactome: R-HSA-8866423;Reactome: R-HSA-8964038;Reactome: R-HSA-8964026;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-8957275;Reactome: R-HSA-202733;Reactome: R-HSA-5686938;Reactome: R-HSA-8856825;Reactome: R-HSA-8963888;Reactome: R-HSA-975634;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-3000480;Reactome: R-HSA-3000484;Reactome: R-HSA-3000471;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL assembly";"LDL clearance";"Chylomicron clearance";"Scavenging by Class H Receptors";"LDL remodeling";"Post-translational protein phosphorylation";"Cell surface interactions at the vascular wall";"Regulation of TLR by endogenous ligand";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly";"Retinoid metabolism and transport";"Chylomicron remodeling";"Platelet sensitization by LDL";"Scavenging by Class A Receptors";"Scavenging by Class F Receptors";"Scavenging by Class B Receptors";"VLDL clearance";"Clathrin-mediated endocytosis"
XP_054086778.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_011188117.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_011182932.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs"
XP_011196052.1	14	MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166	"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Synthesis of PA"
XP_011176910.2	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054083985.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_054090365.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_028897204.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011196010.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_011182376.2	9	KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-7533;Reactome: R-HSA-156590;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18	"Drug metabolism - other enzymes";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis";"Glutathione conjugation";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450"
XP_054091666.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_028894222.2	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054089938.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_028896573.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054084334.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport"
XP_011196639.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_011189030.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011187104.1	11	Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-5689880;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-3214847	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Ub-specific processing proteases";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones"
XP_011181683.1	19	Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-3214858;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-8876725;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-72695;Reactome: R-HSA-156902	"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"RMTs methylate histone arginines";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Protein methylation";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation"
XP_028896579.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_011180765.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_011192145.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011196633.1	3	KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_011192346.2	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_011196378.1	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_011178195.1	10	MetaCyc: PWY-1042;KEGG: 00562+5.3.1.1;MetaCyc: PWY-7003;KEGG: 00710+5.3.1.1;KEGG: 00051+5.3.1.1;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00010+5.3.1.1	"Glycolysis IV (plant cytosol)";"Inositol phosphate metabolism";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Glycolysis";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis"
XP_011178396.1	29	Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-73776	"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"mRNA Capping";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape"
XP_054092034.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_028894355.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011191443.2	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_011181361.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_011196875.2	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_028899698.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_011185195.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011180003.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054085423.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-164378	"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Purine metabolism";"G alpha (s) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation in glucagon signalling"
XP_054086440.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_028898031.2	6	Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_011176546.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054090755.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_011188764.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_011196782.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_011193286.2	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_028898875.1	6	MetaCyc: PWY-7433;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290	"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_028901971.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_011196700.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054083465.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_054089535.1	5	Reactome: R-HSA-9033500;KEGG: 00565+2.5.1.26;Reactome: R-HSA-75896;Reactome: R-HSA-9033241;MetaCyc: PWY-7782	"TYSND1 cleaves peroxisomal proteins";"Ether lipid metabolism";"Plasmalogen biosynthesis";"Peroxisomal protein import";"Plasmalogen biosynthesis"
XP_011183219.1	7	Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-1655829;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-6784531;Reactome: R-HSA-180746	"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"tRNA processing in the nucleus";"Nuclear import of Rev protein"
XP_011184568.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_054091165.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_011181069.1	7	Reactome: R-HSA-5362798;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5658034;Reactome: R-HSA-5632681	"Release of Hh-Np from the secreting cell";"Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"HHAT G278V abrogates palmitoylation of Hh-Np";"Ligand-receptor interactions"
XP_011190246.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054084489.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-166166	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade"
XP_011182676.2	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_054087231.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_054091922.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_054090823.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054090864.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_011193094.1	56	Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_011187575.2	4	KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;Reactome: R-HSA-70688;MetaCyc: PWY-6922	"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_011177391.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011191536.2	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_054090665.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054088447.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054083588.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_011182504.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011190502.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011185182.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_011187819.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_011176474.1	22	Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-432142	"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL"
XP_011185837.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011182274.3	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_028899343.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_028897501.2	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_054091547.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-442982	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_011189306.1	6	KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7290	"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_054085033.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_011194405.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_011178747.2	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_054082572.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_028898421.2	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_028897774.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_054085736.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_011185942.2	2	Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
XP_011181611.2	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_054090381.1	10	Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23	"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"HS-GAG degradation";"Galactose metabolism";"Other glycan degradation"
XP_028896067.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_054090061.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269	"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_028897644.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_054087668.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_011177516.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054089533.1	5	Reactome: R-HSA-9033500;Reactome: R-HSA-75896;Reactome: R-HSA-9033241;MetaCyc: PWY-7782;KEGG: 00565+2.5.1.26	"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Peroxisomal protein import";"Plasmalogen biosynthesis";"Ether lipid metabolism"
XP_011182903.2	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
XP_011181013.2	7	Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-9033241;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Peroxisomal protein import";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054081656.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_011187573.2	4	MetaCyc: PWY-5737;Reactome: R-HSA-70688;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2	"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism"
XP_011193850.2	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_011178984.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_011189083.2	16	Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-2467813	"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids"
XP_011194895.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_028900422.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054085035.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_011182043.2	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_054088658.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-6807505;Reactome: R-HSA-983168	"Protein ubiquitination";"RNA polymerase II transcribes snRNA genes";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054084122.1	9	MetaCyc: PWY-8052;Reactome: R-HSA-416476;MetaCyc: PWY-6367;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039	"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_054087104.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Mitotic Prometaphase";"Aggrephagy";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_054089030.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_011179401.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054083034.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_011178429.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-429958	"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_011177710.1	2	Reactome: R-HSA-140875;Reactome: R-HSA-202733	"Common Pathway of Fibrin Clot Formation";"Cell surface interactions at the vascular wall"
XP_011189502.2	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_028896668.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_011190166.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_011190365.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_028899986.2	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_011189027.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011188262.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
XP_011177458.2	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin"
XP_011179836.1	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Cyanoamino acid metabolism"
XP_054085791.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_028896296.2	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_011185218.2	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_054081327.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011185610.1	10	Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5684264;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-2871837	"Neddylation";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation"
XP_054082459.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_011191298.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_011186472.2	4	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;Reactome: R-HSA-2161541	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism"
XP_054083989.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_054091857.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_054090818.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011191249.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_054085425.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-170670	"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Purine metabolism";"G alpha (z) signalling events";"G alpha (s) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway"
XP_054081870.1	18	KEGG: 04151+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-6783310;Reactome: R-HSA-3371453;Reactome: R-HSA-9633012;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-1221632;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Relaxin signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Fanconi Anemia Pathway";"Regulation of HSF1-mediated heat shock response";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"G2/M DNA damage checkpoint";"Meiotic synapsis";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Human papillomavirus infection";"Thermogenesis"
XP_054090056.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism"
XP_054089420.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_011179641.2	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation"
XP_028897152.2	7	KEGG: 00562+2.7.1.67;MetaCyc: PWY-6351;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660499	"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane"
XP_011196925.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_011196267.2	11	Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-6785631;Reactome: R-HSA-5673001;Reactome: R-HSA-8847993;Reactome: R-HSA-1250196;Reactome: R-HSA-1963642;Reactome: R-HSA-1227986	"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Regulates Cell Motility";"RAF/MAP kinase cascade";"ERBB2 Activates PTK6 Signaling";"SHC1 events in ERBB2 signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB2"
XP_054084794.1	13	Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52	"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series"
XP_011196417.2	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
XP_054081661.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_011188307.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_054083517.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_054090753.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_011190011.2	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_011193504.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187	"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_011195876.2	3	MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531	"Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus"
XP_011191789.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_011196914.2	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_011184338.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_011179916.2	14	MetaCyc: PWY-5497;MetaCyc: PWY-2161;MetaCyc: PWY-3661;KEGG: 00260+2.1.2.1;KEGG: 00680+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-3841;MetaCyc: PWY-181;KEGG: 00670+2.1.2.1;KEGG: 00460+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-2201;MetaCyc: PWY-3661-1	"Purine nucleobases degradation II (anaerobic)";"Folate polyglutamylation";"Glycine betaine degradation I";"Glycine, serine and threonine metabolism";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Folate transformations II (plants)";"Photorespiration ";"One carbon pool by folate";"Cyanoamino acid metabolism";"Metabolism of folate and pterines";"Folate transformations I";"Glycine betaine degradation II (mammalian)"
XP_054082504.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054090502.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_011179557.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054088358.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_011187042.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054091494.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_054091840.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_028899490.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_011194251.2	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_011191922.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_054086131.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_054090363.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_011190887.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054083983.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_011178199.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054091181.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011196442.2	7	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins"
XP_011192989.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation"
XP_011178148.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_011189663.2	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_011187980.1	4	MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32	"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism"
XP_054090220.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_054087368.1	18	MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1483166	"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA"
XP_028895626.1	14	Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-6796648	"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes"
XP_054090681.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_011178846.2	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_054091826.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_054084878.1	3	Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361	"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_028898602.1	4	Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827	"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_011192187.3	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_028895054.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_011188607.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_011187815.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_028898335.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011180659.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_011179862.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054088801.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_011177731.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725	"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_054086393.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_011193201.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214	"Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs"
XP_011182697.1	18	KEGG: 00950+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-5913;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00250+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6642	"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism";"Sulfolactate degradation III";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Arginine biosynthesis";"Coenzyme M biosynthesis II";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"Novobiocin biosynthesis";"(R)-cysteate degradation"
XP_011193622.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_028901884.2	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_011180781.1	57	Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5687128	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling"
XP_054085396.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_011179134.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011192570.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011189315.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011177841.2	10	Reactome: R-HSA-400206;Reactome: R-HSA-983231;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-9022699;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702;Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-9022692	"Regulation of lipid metabolism by PPARalpha";"Factors involved in megakaryocyte development and platelet production";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"Regulation of MECP2 expression and activity"
XP_011183419.2	10	MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-4061	"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I"
XP_011189116.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_011182752.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011177259.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054088765.1	20	KEGG: 00720+2.3.3.8;Reactome: R-HSA-75105;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;Reactome: R-HSA-6798695;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-6728;Reactome: R-HSA-163765;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00020+2.3.3.8;Reactome: R-HSA-1268020;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5172	"Carbon fixation pathways in prokaryotes";"Fatty acyl-CoA biosynthesis";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Neutrophil degranulation";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"ChREBP activates metabolic gene expression";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Mitochondrial protein import";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)"
XP_011196638.1	5	Reactome: R-HSA-191273;KEGG: 00900+2.7.4.2;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-2426168	"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)"
XP_011177526.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_011181280.2	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_054089939.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_054082650.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_054090815.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011185465.2	5	MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis"
XP_011178406.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_054086779.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011182710.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011187669.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_011176683.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341	"mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors"
XP_011178269.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_011177903.1	17	KEGG: 04660+3.1.3.16;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-167243;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Th1 and Th2 cell differentiation"
XP_054081642.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054084150.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011196037.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_054082551.1	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_011188353.1	5	KEGG: 00240+6.3.4.2;MetaCyc: PWY-7185;MetaCyc: PWY-7177;Reactome: R-HSA-499943;MetaCyc: PWY-7176	"Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"UTP and CTP dephosphorylation II";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis"
XP_011185075.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011190575.2	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054087665.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_028894412.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_011190687.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_011187580.1	56	Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-1236974	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway"
XP_054086120.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_054090707.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011183820.1	5	KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084	"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_054090042.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_054091788.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_054083583.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_028895941.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054088994.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-202040	"PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation"
XP_054082566.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_011186800.2	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_011187324.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_054088854.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_028899399.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68962	"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex"
XP_011185930.1	24	Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878	"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"RHO GTPases Activate Formins";"Gap junction assembly";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Aggrephagy";"COPI-mediated anterograde transport"
XP_054087574.1	14	MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-7589	"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_054089364.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_011184060.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_011186901.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_011190368.1	12	KEGG: 00710+4.1.2.13;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-7385;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142	"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_028897959.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_011189172.2	28	Reactome: R-HSA-110312;Reactome: R-HSA-69166;Reactome: R-HSA-5693607;Reactome: R-HSA-3371453;Reactome: R-HSA-5696397;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-5358606;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-3371511;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942	"Translesion synthesis by REV1";"Removal of the Flap Intermediate";"Processing of DNA double-strand break ends";"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"HSF1 activation";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Meiotic recombination";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)"
XP_011189534.2	5	Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-1834949	"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA"
XP_054090902.1	6	MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_054091248.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_011187681.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_011187786.1	7	KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;MetaCyc: PWY-6363;MetaCyc: PWY-2301	"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis"
XP_011185588.2	13	Reactome: R-HSA-416482;Reactome: R-HSA-5687128;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-3928662;Reactome: R-HSA-193648;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"G alpha (12/13) signalling events";"MAPK6/MAPK4 signaling";"Human papillomavirus infection";"Thermogenesis";"Rho GTPase cycle";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"G alpha (q) signalling events";"EPHB-mediated forward signaling";"NRAGE signals death through JNK";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_011194395.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054082347.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_054083414.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011192917.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_011193904.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_011183592.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_028897953.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_011180004.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_011193347.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_028898634.1	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_011180167.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_011187089.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054083556.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_028901520.1	4	Reactome: R-HSA-912631;Reactome: R-HSA-8875555;Reactome: R-HSA-186763;Reactome: R-HSA-8875656	"Regulation of signaling by CBL";"MET activates RAP1 and RAC1";"Downstream signal transduction";"MET receptor recycling"
XP_054083229.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_011193760.1	5	MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20	"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_054091597.1	5	Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-3108214	"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins"
XP_054083589.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_011191851.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_011183468.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_028893816.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_011195453.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054089754.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_011195045.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-76042	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_028897893.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_054081960.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_054088161.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_011176971.2	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_011196338.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054088276.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_028897076.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054082532.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011178413.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_054082647.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_011187061.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_028893672.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"HDACs deacetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_011177909.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_028895449.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011176434.1	5	Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389957	"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_011181952.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_011193590.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_011178263.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_054083871.1	4	KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2	"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_054086490.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054088355.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_011176656.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054086773.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011193612.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_011196292.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_028899702.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011185567.1	10	Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-73779	"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_054087085.1	5	Reactome: R-HSA-376172;Reactome: R-HSA-171007;Reactome: R-HSA-168638;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24	"DSCAM interactions";"p38MAPK events";"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway"
XP_011190775.3	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_028896578.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_011194954.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054081617.1	9	MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1	"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism"
XP_011177098.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_011186343.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_011190387.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_011196461.2	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_054085570.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011185542.2	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054090806.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_054086232.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011182566.1	6	KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7426;Reactome: R-HSA-4793952	"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_011187864.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054088353.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_054086643.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_028899300.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_028893608.2	1	Reactome: R-HSA-5676934	"Protein repair"
XP_011179691.2	13	KEGG: 00983+2.5.1.18;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6842;Reactome: R-HSA-156590;MetaCyc: PWY-2261;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-7112;MetaCyc: PWY-6370;Reactome: R-HSA-196836;MetaCyc: PWY-7533;MetaCyc: PWY-4061	"Drug metabolism - other enzymes";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Ascorbate glutathione cycle";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Ascorbate recycling (cytosolic)";"Vitamin C (ascorbate) metabolism";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I"
XP_011190707.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_054089070.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_011192218.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-6906;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514	"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_028899457.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011192592.1	13	MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Hyaluronan uptake and degradation";"CS/DS degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation"
XP_054083988.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_028899160.2	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_011191248.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_054090819.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011190902.1	5	MetaCyc: PWY-6892;MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560	"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II"
XP_054083846.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_011183527.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_011178143.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_011182347.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_028896103.1	12	Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-5362798;Reactome: R-HSA-1251985;Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-75893;Reactome: R-HSA-193692;Reactome: R-HSA-982772;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Release of Hh-Np from the secreting cell";"Nuclear signaling by ERBB4";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"TNF signaling";"Regulated proteolysis of p75NTR";"Growth hormone receptor signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation"
XP_011189084.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_011187887.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_054091007.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_011184077.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_054089935.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_028894072.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_011182760.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_028900729.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_011179551.1	10	KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096	"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Neutrophil degranulation";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Other glycan degradation";"HS-GAG degradation"
XP_011192331.2	7	KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921;Reactome: R-HSA-5628897	"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes"
XP_011184639.2	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_028897955.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_011190614.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
NP_001291679.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_054091295.1	4	Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054081830.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_054081107.1	5	KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749	"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I"
XP_011194272.2	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_054086398.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_054085419.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-5610787	"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (s) signalling events";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state"
XP_011180247.2	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_011192677.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_011184513.2	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_054087669.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_011196906.1	1	Reactome: R-HSA-419771	"Opsins"
XP_028901025.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_011185079.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011189629.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_011196874.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012	"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_011195043.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation"
XP_028894117.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054084221.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011195916.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_054087624.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_011191672.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_011191244.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054087663.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_054082841.1	3	Reactome: R-HSA-392517;Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Rap1 signalling";"Ca2+ pathway";"cGMP effects"
XP_011190277.2	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6787450	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_011180057.2	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_054083585.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054086266.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_011195557.1	17	Reactome: R-HSA-6798695;MetaCyc: PWY-4202;MetaCyc: PWY-6608;MetaCyc: PWY-7179;KEGG: 00240+2.4.2.1;Reactome: R-HSA-74217;MetaCyc: PWY-6620;MetaCyc: PWY-5695;MetaCyc: PWY-6644;MetaCyc: PWY-5532;MetaCyc: PWY-6627;Reactome: R-HSA-74259;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-6609;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179-1	"Neutrophil degranulation";"Arsenate detoxification I (mammalian)";"Guanosine nucleotides degradation III";"Purine deoxyribonucleosides degradation I";"Pyrimidine metabolism";"Purine salvage";"Guanine and guanosine salvage";"Inosine 5'-phosphate degradation";"Fluoroacetate and fluorothreonine biosynthesis";"Nucleoside and nucleotide degradation (archaea)";"Salinosporamide A biosynthesis";"Purine catabolism";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Purine metabolism";"Purine deoxyribonucleosides degradation II"
XP_054087061.1	30	Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-2565942;Reactome: R-HSA-5676590;Reactome: R-HSA-5684264;Reactome: R-HSA-2122947;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-400253;Reactome: R-HSA-69231;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-1170546;Reactome: R-HSA-917937;Reactome: R-HSA-2644606;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-2644607;Reactome: R-HSA-5607761;Reactome: R-HSA-9020702;Reactome: R-HSA-2894862	"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PLK1 Activity at G2/M Transition";"NIK-->noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Circadian Clock";"Cyclin D associated events in G1";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Prolactin receptor signaling";"Iron uptake and transport";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_011185671.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_011196529.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_054091604.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_011179254.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_011187085.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054088653.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"RNA polymerase II transcribes snRNA genes";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011190625.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_011185570.1	10	Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-3214847;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_028899600.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011188949.2	9	MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;Reactome: R-HSA-416476;MetaCyc: PWY-6367;MetaCyc: PWY-8052	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"PLC beta mediated events";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis"
XP_011181617.1	11	KEGG: 00240+6.3.5.5;MetaCyc: PWY-7400;MetaCyc: PWY-7791;MetaCyc: PWY-5154;KEGG: 00250+2.1.3.2;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5686;Reactome: R-HSA-500753;MetaCyc: PWY-7790;KEGG: 00240+3.5.2.3;KEGG: 00240+2.1.3.2	"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis III";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis";"UMP biosynthesis II";"Pyrimidine metabolism";"Pyrimidine metabolism"
XP_011192214.2	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_011188189.1	7	Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-110362;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-2173795;Reactome: R-HSA-5685939	"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"HDR through MMEJ (alt-NHEJ)"
XP_011191125.2	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_028896663.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054082102.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054088051.1	12	Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9609736	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Long-term potentiation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors"
XP_011196261.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_011179647.1	3	Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-5696394	"UCH proteinases";"HATs acetylate histones";"DNA Damage Recognition in GG-NER"
XP_054084879.1	3	MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_054087369.1	18	Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925	"Acyl chain remodelling of PS";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG"
XP_011192148.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054088544.1	4	Reactome: R-HSA-2161541;Reactome: R-HSA-499943;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054085911.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011192846.1	20	MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-7291;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-7337;MetaCyc: PWY-6920;MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-5136;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"
XP_054088066.1	12	Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308;Reactome: R-HSA-8849932	"Long-term potentiation";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules"
XP_028900900.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054092080.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_011178198.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_054090813.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_011193336.2	29	Reactome: R-HSA-69541;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693565;KEGG: 05163+2.7.11.1;Reactome: R-HSA-912446;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-6804760;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693568;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6803204;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-6796648;Reactome: R-HSA-69473;Reactome: R-HSA-6803207;Reactome: R-HSA-5693607;Reactome: R-HSA-3371453;Reactome: R-HSA-5693616;Reactome: R-HSA-6804757;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756;Reactome: R-HSA-349425	"Stabilization of p53";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Human cytomegalovirus infection";"Meiotic recombination";"Relaxin signaling pathway";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Methylation";"PI3K-Akt signaling pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Thermogenesis";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Human papillomavirus infection";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"TP53 Regulates Transcription of DNA Repair Genes";"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Processing of DNA double-strand break ends";"Regulation of HSF1-mediated heat shock response";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Degradation";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_011186216.2	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_011187829.1	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_054088359.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_054081388.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_011185198.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054086649.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_011190460.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054083468.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011192820.1	57	Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-1169091	"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells"
XP_011183589.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_028898878.1	6	MetaCyc: PWY-7433;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290	"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_011180020.1	4	Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-72086	"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping"
XP_054081641.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_011192245.2	9	Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-4420332	"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1"
XP_011193006.1	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_011182473.1	5	KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781;MetaCyc: PWY-6692;MetaCyc: PWY-7279;MetaCyc: PWY-7082	"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)"
XP_054082510.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011184858.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_054084476.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_011187695.1	4	MetaCyc: PWY-5350;Reactome: R-HSA-1614558;KEGG: 00920+2.8.1.1;MetaCyc: PWY-7927	"Thiosulfate disproportionation IV (rhodanese)";"Degradation of cysteine and homocysteine";"Sulfur metabolism";"Sulfide oxidation IV (mitochondria)"
XP_011191406.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_011196040.2	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_011185448.2	5	MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_028898543.1	3	Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial protein import"
XP_054090398.1	6	Reactome: R-HSA-114516;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-5099900	"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4"
XP_054088528.1	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_011193019.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_054082013.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_011194535.1	8	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269	"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Signaling by Hippo"
XP_011177274.2	1	Reactome: R-HSA-376172	"DSCAM interactions"
XP_054081903.1	14	MetaCyc: PWY-6453;Reactome: R-HSA-9033241;MetaCyc: PWY-7587;Reactome: R-HSA-75896;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.42;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15	"Stigma estolide biosynthesis";"Peroxisomal protein import";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism"
XP_011184998.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902	"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation"
XP_011183294.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054087408.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_028898142.2	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_011195830.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
XP_054084090.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_054083603.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_011179689.2	13	MetaCyc: PWY-6370;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-4061;MetaCyc: PWY-7533;Reactome: R-HSA-196836;MetaCyc: PWY-6842;KEGG: 00053+1.8.5.1;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-2261;Reactome: R-HSA-156590	"Ascorbate recycling (cytosolic)";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification II";"Ascorbate and aldarate metabolism";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Ascorbate glutathione cycle";"Glutathione conjugation"
XP_011181486.2	5	Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-1655829	"MHC class II antigen presentation";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_011184301.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054085248.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_011196436.2	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_028899365.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_028899271.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_028893469.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054091038.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054090901.1	6	MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_054084945.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_011185522.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_011186902.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_011191930.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_011183305.1	5	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1679131;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Trafficking and processing of endosomal TLR";"MHC class II antigen presentation";"Neutrophil degranulation"
XP_028900749.2	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_028897819.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054090232.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_011185304.1	4	MetaCyc: PWY-4361;MetaCyc: PWY-7174;Reactome: R-HSA-72731;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP";"Cysteine and methionine metabolism"
XP_011178742.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_011179817.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054083730.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_054087648.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_054086806.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054090041.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054084005.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_011185947.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_011192826.2	6	KEGG: 00520+2.7.7.12;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317;Reactome: R-HSA-70370;Reactome: R-HSA-5609978;MetaCyc: PWY-6527	"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Defective GALT can cause Galactosemia";"Stachyose degradation"
XP_011179732.2	9	Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape"
XP_054086477.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_011177342.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011186252.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_011178129.2	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_011191852.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054086296.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054092106.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011176972.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_011179101.1	12	KEGG: 00270+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-601;MetaCyc: PWY-7901;MetaCyc: PWY-1187;MetaCyc: PWY-2821;MetaCyc: PWY-6936;KEGG: 00380+2.6.1.7;KEGG: 00450+4.4.1.13;Reactome: R-HSA-71240;MetaCyc: PWY-6309;MetaCyc: PWY-801	"Cysteine and methionine metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)";"Tryptophan metabolism";"Selenocompound metabolism";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Homocysteine and cysteine interconversion"
XP_011192128.1	3	KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Porphyrin and chlorophyll metabolism";"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
XP_054083616.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_011180411.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054085597.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011180878.2	5	MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7766;MetaCyc: PWY-7159	"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_011183591.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_028896091.2	3	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion"
XP_011176777.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011195667.2	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_011196768.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054084715.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_011184441.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_011194363.2	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_011192536.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_011185129.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_011179683.2	14	Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-674695	"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events"
XP_054085293.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_011182101.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)"
XP_011184765.2	4	KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210;MetaCyc: PWY-6517;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Chitin derivatives degradation"
XP_011189232.2	10	MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-7112;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4061;MetaCyc: PWY-5826	"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis"
XP_011181812.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_011191413.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_011196462.2	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_028893570.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054088918.1	13	MetaCyc: PWY-7102;MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-5122;MetaCyc: PWY-7659;MetaCyc: PWY-7182;MetaCyc: PWY-6383;MetaCyc: PWY-6859;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-7410;MetaCyc: PWY-5123	"Bisabolene biosynthesis (engineered)";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Geranyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Linalool biosynthesis I";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Terpenoid backbone biosynthesis";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Ipsdienol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis"
XP_011184183.2	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_011178168.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_011183605.1	3	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism"
XP_054089959.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_054088096.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-163359	"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"G alpha (s) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation"
XP_028899701.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054091860.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_011189067.3	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_028894919.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_028898291.2	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_054084599.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_011186277.2	3	KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271	"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"Fructose and mannose metabolism"
XP_011180485.2	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_011181990.1	18	KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7224;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7227;MetaCyc: PWY-7184;MetaCyc: PWY-7226;MetaCyc: PWY-7222;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7205;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197	"Purine metabolism";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation"
XP_011193709.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_054082531.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011191985.2	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_011182842.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_054083872.1	4	MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817	"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_054091671.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_011182361.2	4	Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178;Reactome: R-HSA-3000170	"Integrin cell surface interactions";"Molecules associated with elastic fibres";"ECM proteoglycans";"Syndecan interactions"
XP_011190490.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_011190844.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_054091646.1	16	Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569	"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_011186088.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_011192512.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_011186021.2	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228	"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix"
XP_054086902.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_011192591.1	13	KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52	"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Other glycan degradation";"Various types of N-glycan biosynthesis"
XP_011183603.1	3	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism"
XP_028894071.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)"
XP_011189844.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_028893646.1	22	Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_011192550.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_011178541.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054090146.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_028894525.1	15	Reactome: R-HSA-9009391;Reactome: R-HSA-1266695;Reactome: R-HSA-6811558;Reactome: R-HSA-912526;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-912631;Reactome: R-HSA-1433557;Reactome: R-HSA-1660499;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-114604;Reactome: R-HSA-416476;Reactome: R-HSA-388841;Reactome: R-HSA-389357	"Extra-nuclear estrogen signaling";"Interleukin-7 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin receptor SHC signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"Regulation of signaling by CBL";"Signaling by SCF-KIT";"Synthesis of PIPs at the plasma membrane";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"GPVI-mediated activation cascade";"G alpha (q) signalling events";"Costimulation by the CD28 family";"CD28 dependent PI3K/Akt signaling"
XP_054086828.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_054091620.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054091075.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_011187624.3	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_054088421.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011179013.1	3	Reactome: R-HSA-71336;KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44	"Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway"
XP_011192249.2	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_028899328.2	1	Reactome: R-HSA-3000178	"ECM proteoglycans"
XP_011193356.2	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_054085282.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1	"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism"
XP_054087733.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011192298.2	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_011196714.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_011179611.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_011191428.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054088700.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011192666.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054084009.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_011186431.2	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_011191079.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_011182709.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_011177830.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_011183309.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_028895487.2	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_011189209.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054082596.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_011185482.2	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_054089558.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_011177384.2	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_011182153.2	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054088964.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011189466.1	4	Reactome: R-HSA-77289;Reactome: R-HSA-611105;Reactome: R-HSA-389661;Reactome: R-HSA-6799198	"Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis"
XP_011190895.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054086815.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_011194868.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_054089394.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_054087426.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_054084949.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_011196886.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054085295.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_011179884.2	15	MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-7003;MetaCyc: PWY-5723;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6142;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-6901	"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Glycolysis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation"
XP_011177087.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011190398.1	57	Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-69601	"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Neutrophil degranulation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_054082817.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_011183115.1	5	KEGG: 00513+2.4.1.68;MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.68;KEGG: 00533+2.4.1.68	"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate"
XP_011191194.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_011194166.2	6	KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6363	"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_011188918.1	7	Reactome: R-HSA-70268;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00010+1.2.4.1	"Pyruvate metabolism";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis"
XP_054083976.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_054091224.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_011182946.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054084719.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_011190409.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_011176796.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion"
XP_028896062.2	40	Reactome: R-HSA-75955;Reactome: R-HSA-72203;Reactome: R-HSA-112382;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-5601884;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-167162;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-5578749;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-167246	"RNA Polymerase II Transcription Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of RNA Pol II elongation complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"PIWI-interacting RNA (piRNA) biogenesis";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"RNA Polymerase II HIV Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Transcriptional regulation by small RNAs";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript"
XP_011192390.1	83	Reactome: R-HSA-5637810;Reactome: R-HSA-2219530;Reactome: R-HSA-8875656;Reactome: R-HSA-5654712;Reactome: R-HSA-9664565;Reactome: R-HSA-74751;Reactome: R-HSA-2424491;Reactome: R-HSA-5654688;Reactome: R-HSA-8853338;Reactome: R-HSA-9634285;Reactome: R-HSA-8875360;Reactome: R-HSA-354194;Reactome: R-HSA-179812;Reactome: R-HSA-6811558;Reactome: R-HSA-5655302;Reactome: R-HSA-5654727;Reactome: R-HSA-5654689;Reactome: R-HSA-8851805;Reactome: R-HSA-6807004;Reactome: R-HSA-186763;Reactome: R-HSA-5654700;Reactome: R-HSA-1236382;Reactome: R-HSA-1963642;Reactome: R-HSA-5654726;Reactome: R-HSA-180336;Reactome: R-HSA-182971;Reactome: R-HSA-1257604;Reactome: R-HSA-2871796;Reactome: R-HSA-5654732;Reactome: R-HSA-74749;Reactome: R-HSA-388841;Reactome: R-HSA-8856828;Reactome: R-HSA-167044;Reactome: R-HSA-8853659;Reactome: R-HSA-8851907;Reactome: R-HSA-1433557;Reactome: R-HSA-1250196;Reactome: R-HSA-2871809;Reactome: R-HSA-8856825;Reactome: R-HSA-983695;Reactome: R-HSA-2730905;Reactome: R-HSA-2428933;Reactome: R-HSA-2029482;Reactome: R-HSA-5655291;Reactome: R-HSA-8875555;Reactome: R-HSA-9034864;Reactome: R-HSA-1963640;Reactome: R-HSA-112412;Reactome: R-HSA-5654733;Reactome: R-HSA-1295596;Reactome: R-HSA-9026519;Reactome: R-HSA-375165;Reactome: R-HSA-210993;Reactome: R-HSA-9027284;Reactome: R-HSA-180292;Reactome: R-HSA-512988;Reactome: R-HSA-5654704;Reactome: R-HSA-5655253;Reactome: R-HSA-5663213;Reactome: R-HSA-5654710;Reactome: R-HSA-9645135;Reactome: R-HSA-5673001;Reactome: R-HSA-8865999;Reactome: R-HSA-391160;Reactome: R-HSA-5654719;Reactome: R-HSA-1433559;Reactome: R-HSA-5654720;Reactome: R-HSA-9028335;Reactome: R-HSA-9607240;Reactome: R-HSA-389359;Reactome: R-HSA-109704;Reactome: R-HSA-8853334;Reactome: R-HSA-912631;Reactome: R-HSA-1250347;Reactome: R-HSA-5654706;Reactome: R-HSA-8983432;Reactome: R-HSA-5654693;Reactome: R-HSA-912526;Reactome: R-HSA-9028731;Reactome: R-HSA-5654695;Reactome: R-HSA-5654699;Reactome: R-HSA-2179392;Reactome: R-HSA-1839117	"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Aberrant PI3K in Cancer";"MET receptor recycling";"FRS-mediated FGFR4 signaling";"Signaling by ERBB2 KD Mutants";"Insulin receptor signalling cascade";"DAP12 signaling";"SHC-mediated cascade:FGFR1";"Signaling by FGFR3 point mutants in cancer";"Constitutive Signaling by Overexpressed ERBB2";"InlB-mediated entry of Listeria monocytogenes into host cell";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"GRB2 events in EGFR signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by FGFR1 in disease";"Negative regulation of FGFR2 signaling";"PI-3K cascade:FGFR1";"MET activates RAS signaling";"Negative regulation of MET activity";"Downstream signal transduction";"FRS-mediated FGFR2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"PI3K events in ERBB2 signaling";"Negative regulation of FGFR1 signaling";"SHC1 events in EGFR signaling";"EGFR downregulation";"PIP3 activates AKT signaling";"FCERI mediated MAPK activation";"Negative regulation of FGFR3 signaling";"Signal attenuation";"Costimulation by the CD28 family";"Clathrin-mediated endocytosis";"Signalling to RAS";"RET signaling";"MET activates PI3K/AKT signaling";"Signaling by SCF-KIT";"SHC1 events in ERBB2 signaling";"FCERI mediated Ca+2 mobilization";"Cargo recognition for clathrin-mediated endocytosis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Role of LAT2/NTAL/LAB on calcium mobilization";"SHC-related events triggered by IGF1R";"Regulation of actin dynamics for phagocytic cup formation";"Signaling by FGFR4 in disease";"MET activates RAP1 and RAC1";"Activated NTRK3 signals through RAS";"GRB2 events in ERBB2 signaling";"SOS-mediated signalling";"Negative regulation of FGFR4 signaling";"Spry regulation of FGF signaling";"Activated NTRK2 signals through RAS";"NCAM signaling for neurite out-growth";"Tie2 Signaling";"Erythropoietin activates RAS";"GAB1 signalosome";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"SHC-mediated cascade:FGFR3";"Signaling by FGFR2 in disease";"RHO GTPases Activate WASPs and WAVEs";"PI-3K cascade:FGFR3";"STAT5 Activation";"RAF/MAP kinase cascade";"MET activates PTPN11";"Signal regulatory protein family interactions";"SHC-mediated cascade:FGFR4";"Regulation of KIT signaling";"PI-3K cascade:FGFR4";"Activated NTRK2 signals through PI3K";"FLT3 Signaling";"CD28 dependent Vav1 pathway";"PI3K Cascade";"Signaling by FGFR3 fusions in cancer";"Regulation of signaling by CBL";"SHC1 events in ERBB4 signaling";"FRS-mediated FGFR3 signaling";"Interleukin-15 signaling";"FRS-mediated FGFR1 signaling";"Interleukin receptor SHC signaling";"Activated NTRK2 signals through FRS2 and FRS3";"PI-3K cascade:FGFR2";"SHC-mediated cascade:FGFR2";"EGFR Transactivation by Gastrin";"Signaling by cytosolic FGFR1 fusion mutants"
XP_028894141.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054087457.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_054089137.1	3	KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_054082101.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054088052.1	12	Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-451308	"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Long-term potentiation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor"
XP_011179475.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_011197010.1	13	KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802955;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802948;Reactome: R-HSA-9649948;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802946	"PI3K-Akt signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Relaxin signaling pathway";"Signaling by high-kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Human papillomavirus infection";"Human cytomegalovirus infection";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Signaling by moderate kinase activity BRAF mutants"
XP_028895331.2	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_054082842.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_011191776.1	8	MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-6609;Reactome: R-HSA-5683826;MetaCyc: PWY-6611	"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Adenine and adenosine salvage III";"Surfactant metabolism";"Adenine and adenosine salvage V"
XP_011182159.2	5	MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_054084222.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011189345.2	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_028893584.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011185672.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_054084003.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_011193689.2	4	MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;Reactome: R-HSA-964975	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate"
XP_054087062.1	5	Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-380972	"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Macroautophagy";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_011184130.1	13	Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206308;Reactome: R-HSA-4085001;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-4341670;KEGG: 00600+3.2.1.23	"HS-GAG degradation";"Other glycan degradation";"MPS IV - Morquio syndrome B";"Sialic acid metabolism";"Galactose metabolism";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Defective NEU1 causes sialidosis";"Sphingolipid metabolism"
XP_028895677.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011189848.1	6	MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-7442;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664	"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II"
XP_011178962.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054081990.1	8	Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Activation of RAC1";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_011188267.2	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054088333.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054086210.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_028901138.2	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_011191989.2	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_011194864.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011192243.2	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_028893797.2	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_054084595.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_028901836.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_011196944.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_011185816.1	5	Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
XP_054085444.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_011188284.2	4	Reactome: R-HSA-9615710;Reactome: R-HSA-9646399;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300	"Late endosomal microautophagy";"Aggrephagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors"
XP_011183609.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011195025.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054089955.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_011181862.2	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_028897157.1	32	Reactome: R-HSA-167238;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-6803529;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-168325;Reactome: R-HSA-72165;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-72203;Reactome: R-HSA-112382	"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"Viral Messenger RNA Synthesis";"mRNA Splicing - Minor Pathway";"mRNA Capping";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of RNA Pol II elongation complex"
XP_054091911.1	4	Reactome: R-HSA-352230;Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-5660862	"Amino acid transport across the plasma membrane";"Basigin interactions";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)"
XP_011179531.1	3	Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-525793	"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis"
XP_054092001.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187	"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_054081771.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_011192366.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011179159.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011187110.1	11	Reactome: R-HSA-3214847;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-5689880;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042	"HATs acetylate histones";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"Ub-specific processing proteases";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_011178118.2	4	Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_011177068.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_054087196.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011179469.1	16	Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-167287;Reactome: R-HSA-8951664;Reactome: R-HSA-167246;Reactome: R-HSA-167238	"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery";"Neddylation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation"
XP_054086639.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_011186096.1	13	KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"CS/DS degradation";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_011192259.2	5	Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9615710	"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Late endosomal microautophagy"
XP_011194230.1	6	Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957	"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_028898204.2	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_011185650.2	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_054085509.1	1	Reactome: R-HSA-419771	"Opsins"
XP_054090355.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011193320.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011195429.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_011177035.1	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_011189655.2	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_054085752.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_011196382.1	6	Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.64+3.1.3.95;KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6367;MetaCyc: PWY-6580;MetaCyc: PWY-6368	"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"3-phosphoinositide degradation"
XP_011179637.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_011178590.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_028900606.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_011181512.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_011180613.2	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_011184041.2	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_054090161.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_011186925.1	3	MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9	"Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis"
XP_028898196.2	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_011187072.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_054091024.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_028895278.2	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_054090497.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054088460.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054087004.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_011190724.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_011195610.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_028898958.1	4	Reactome: R-HSA-611105;Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-6799198	"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis"
XP_054084848.1	5	Reactome: R-HSA-9646399;Reactome: R-HSA-983168;Reactome: R-HSA-5205685;Reactome: R-HSA-5689877;Reactome: R-HSA-977225	"Aggrephagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Pink/Parkin Mediated Mitophagy";"Josephin domain DUBs";"Amyloid fiber formation"
XP_011179194.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_054091560.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_011193797.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_011177425.1	9	Reactome: R-HSA-2871809;Reactome: R-HSA-194840;Reactome: R-HSA-2029482;Reactome: R-HSA-2871796;Reactome: R-HSA-4420097;Reactome: R-HSA-114604;Reactome: R-HSA-193648;Reactome: R-HSA-5218920;Reactome: R-HSA-416482	"FCERI mediated Ca+2 mobilization";"Rho GTPase cycle";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated MAPK activation";"VEGFA-VEGFR2 Pathway";"GPVI-mediated activation cascade";"NRAGE signals death through JNK";"VEGFR2 mediated vascular permeability";"G alpha (12/13) signalling events"
XP_011185566.2	4	KEGG: 00860+1.14.14.18;Reactome: R-HSA-917937;Reactome: R-HSA-189483;MetaCyc: PWY-5874	"Porphyrin and chlorophyll metabolism";"Iron uptake and transport";"Heme degradation";"Heme degradation I"
XP_054081792.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054083572.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011182542.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011190544.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_054087450.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_011191273.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054086795.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_028900306.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_011188021.2	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_011194456.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_054081181.1	29	Reactome: R-HSA-912446;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-6783310;Reactome: R-HSA-3371511;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-5696397;Reactome: R-HSA-5696395;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-5693607;Reactome: R-HSA-69166;Reactome: R-HSA-110312;Reactome: R-HSA-176187;Reactome: R-HSA-5358606;Reactome: R-HSA-110320;Reactome: R-HSA-174437;Reactome: R-HSA-68962;Reactome: R-HSA-6804756	"Meiotic recombination";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Fanconi Anemia Pathway";"HSF1 activation";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Formation of Incision Complex in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate";"Translesion synthesis by REV1";"Activation of ATR in response to replication stress";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate from the C-strand";"Activation of the pre-replicative complex";"Regulation of TP53 Activity through Phosphorylation"
XP_054089297.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054090655.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054082797.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_028896714.2	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_011188865.2	11	Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-212436;Reactome: R-HSA-2151201;Reactome: R-HSA-383280	"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Estrogen-dependent gene expression";"Generic Transcription Pathway";"Transcriptional activation of mitochondrial biogenesis";"Nuclear Receptor transcription pathway"
XP_011182149.2	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_011196501.1	4	KEGG: 00510+2.4.1.258;Reactome: R-HSA-4720475;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.258	"N-Glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis"
XP_054088231.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_011177942.2	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_028900319.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_054087714.1	6	Reactome: R-HSA-196807;KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761;MetaCyc: PWY-5653;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_054084953.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_054088828.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_054088042.1	12	Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308;Reactome: R-HSA-8849932	"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules"
XP_028899485.2	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054089090.1	5	Reactome: R-HSA-3134975;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941;Reactome: R-HSA-3249367;Reactome: R-HSA-3270619	"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation";"STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN"
XP_011182956.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011178254.2	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_054086782.1	3	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_054090127.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_011191946.2	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054086700.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_011184416.2	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_011179149.2	5	Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159231	"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_011192697.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_028897242.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054085731.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_028897674.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_011185822.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_011186335.1	5	KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;MetaCyc: PWY-5532	"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)"
XP_054084451.1	3	Reactome: R-HSA-525793;Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Myogenesis";"Ligand-receptor interactions";"Activation of SMO"
XP_054085454.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_011186748.1	13	Reactome: R-HSA-437239;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-8856825;Reactome: R-HSA-182218;Reactome: R-HSA-5140745;Reactome: R-HSA-8866427;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-167590;Reactome: R-HSA-2132295;Reactome: R-HSA-3928665;Reactome: R-HSA-177504	"Recycling pathway of L1";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"VLDLR internalisation and degradation";"LDL clearance";"Clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"MHC class II antigen presentation";"EPH-ephrin mediated repulsion of cells";"Retrograde neurotrophin signalling"
XP_028893937.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_011184409.2	6	Reactome: R-HSA-912446;Reactome: R-HSA-5632987;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5545483;Reactome: R-HSA-6796648	"Meiotic recombination";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MLH1";"TP53 Regulates Transcription of DNA Repair Genes"
XP_011182073.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_011195487.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_054085362.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054086633.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_011186581.2	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_011195917.2	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_028897635.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054083504.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054081789.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054088758.1	8	Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-6798695;Reactome: R-HSA-8953750;Reactome: R-HSA-9627069	"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Neutrophil degranulation";"Transcriptional Regulation by E2F6";"Regulation of the apoptosome activity"
XP_011176950.1	8	KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Activation of RAC1";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_054092094.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_011188252.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_054081512.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054086162.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011193213.1	4	Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis"
XP_054090359.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_011186678.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_028898012.1	6	MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_028898404.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1"
XP_011193896.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054089222.1	83	Reactome: R-HSA-180336;Reactome: R-HSA-5654726;Reactome: R-HSA-182971;Reactome: R-HSA-1963642;Reactome: R-HSA-5654700;Reactome: R-HSA-186763;Reactome: R-HSA-1236382;Reactome: R-HSA-6811558;Reactome: R-HSA-5654727;Reactome: R-HSA-5655302;Reactome: R-HSA-6807004;Reactome: R-HSA-5654689;Reactome: R-HSA-8851805;Reactome: R-HSA-8875360;Reactome: R-HSA-9634285;Reactome: R-HSA-179812;Reactome: R-HSA-354194;Reactome: R-HSA-8853338;Reactome: R-HSA-5654688;Reactome: R-HSA-2424491;Reactome: R-HSA-74751;Reactome: R-HSA-5654712;Reactome: R-HSA-8875656;Reactome: R-HSA-9664565;Reactome: R-HSA-5637810;Reactome: R-HSA-2219530;Reactome: R-HSA-2029482;Reactome: R-HSA-2428933;Reactome: R-HSA-2730905;Reactome: R-HSA-983695;Reactome: R-HSA-8856825;Reactome: R-HSA-8851907;Reactome: R-HSA-2871809;Reactome: R-HSA-1250196;Reactome: R-HSA-1433557;Reactome: R-HSA-167044;Reactome: R-HSA-8853659;Reactome: R-HSA-388841;Reactome: R-HSA-8856828;Reactome: R-HSA-74749;Reactome: R-HSA-1257604;Reactome: R-HSA-5654732;Reactome: R-HSA-2871796;Reactome: R-HSA-5673001;Reactome: R-HSA-5663213;Reactome: R-HSA-9645135;Reactome: R-HSA-5654710;Reactome: R-HSA-5655253;Reactome: R-HSA-5654704;Reactome: R-HSA-512988;Reactome: R-HSA-375165;Reactome: R-HSA-9026519;Reactome: R-HSA-210993;Reactome: R-HSA-180292;Reactome: R-HSA-9027284;Reactome: R-HSA-112412;Reactome: R-HSA-1295596;Reactome: R-HSA-5654733;Reactome: R-HSA-8875555;Reactome: R-HSA-1963640;Reactome: R-HSA-9034864;Reactome: R-HSA-5655291;Reactome: R-HSA-2179392;Reactome: R-HSA-1839117;Reactome: R-HSA-5654699;Reactome: R-HSA-912526;Reactome: R-HSA-5654693;Reactome: R-HSA-9028731;Reactome: R-HSA-5654695;Reactome: R-HSA-8983432;Reactome: R-HSA-5654706;Reactome: R-HSA-9607240;Reactome: R-HSA-109704;Reactome: R-HSA-389359;Reactome: R-HSA-912631;Reactome: R-HSA-1250347;Reactome: R-HSA-8853334;Reactome: R-HSA-5654720;Reactome: R-HSA-9028335;Reactome: R-HSA-391160;Reactome: R-HSA-8865999;Reactome: R-HSA-1433559;Reactome: R-HSA-5654719	"SHC1 events in EGFR signaling";"Negative regulation of FGFR1 signaling";"EGFR downregulation";"PI3K events in ERBB2 signaling";"FRS-mediated FGFR2 signaling";"Downstream signal transduction";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of FGFR2 signaling";"Signaling by FGFR1 in disease";"Negative regulation of MET activity";"PI-3K cascade:FGFR1";"MET activates RAS signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Constitutive Signaling by Overexpressed ERBB2";"GRB2 events in EGFR signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Signaling by FGFR3 point mutants in cancer";"SHC-mediated cascade:FGFR1";"DAP12 signaling";"Insulin receptor signalling cascade";"FRS-mediated FGFR4 signaling";"MET receptor recycling";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Aberrant PI3K in Cancer";"Regulation of actin dynamics for phagocytic cup formation";"SHC-related events triggered by IGF1R";"Role of LAT2/NTAL/LAB on calcium mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Cargo recognition for clathrin-mediated endocytosis";"MET activates PI3K/AKT signaling";"FCERI mediated Ca+2 mobilization";"SHC1 events in ERBB2 signaling";"Signaling by SCF-KIT";"Signalling to RAS";"RET signaling";"Costimulation by the CD28 family";"Clathrin-mediated endocytosis";"Signal attenuation";"PIP3 activates AKT signaling";"Negative regulation of FGFR3 signaling";"FCERI mediated MAPK activation";"RAF/MAP kinase cascade";"RHO GTPases Activate WASPs and WAVEs";"STAT5 Activation";"PI-3K cascade:FGFR3";"Signaling by FGFR2 in disease";"SHC-mediated cascade:FGFR3";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"NCAM signaling for neurite out-growth";"Activated NTRK2 signals through RAS";"Tie2 Signaling";"GAB1 signalosome";"Erythropoietin activates RAS";"SOS-mediated signalling";"Spry regulation of FGF signaling";"Negative regulation of FGFR4 signaling";"MET activates RAP1 and RAC1";"GRB2 events in ERBB2 signaling";"Activated NTRK3 signals through RAS";"Signaling by FGFR4 in disease";"EGFR Transactivation by Gastrin";"Signaling by cytosolic FGFR1 fusion mutants";"SHC-mediated cascade:FGFR2";"Interleukin receptor SHC signaling";"FRS-mediated FGFR1 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"PI-3K cascade:FGFR2";"Interleukin-15 signaling";"FRS-mediated FGFR3 signaling";"FLT3 Signaling";"PI3K Cascade";"CD28 dependent Vav1 pathway";"Regulation of signaling by CBL";"SHC1 events in ERBB4 signaling";"Signaling by FGFR3 fusions in cancer";"PI-3K cascade:FGFR4";"Activated NTRK2 signals through PI3K";"Signal regulatory protein family interactions";"MET activates PTPN11";"Regulation of KIT signaling";"SHC-mediated cascade:FGFR4"
XP_028894938.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_028900615.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_011184203.1	9	KEGG: 00720+6.4.1.1;MetaCyc: PWY-6142;KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-8086;Reactome: R-HSA-196780;MetaCyc: PWY-6146	"Carbon fixation pathways in prokaryotes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism"
XP_011183134.1	14	Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167287	"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery"
XP_054090386.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-76005	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+"
XP_054090544.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_011187412.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_011177193.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607	"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends"
XP_054086635.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_011187004.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_011189548.1	10	Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897;Reactome: R-HSA-111459;Reactome: R-HSA-2151201	"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Respiratory electron transport";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis"
XP_011191560.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_011195712.2	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_054081756.1	4	KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing"
XP_028898050.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_011179269.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_028899230.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054081651.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054090051.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_054087658.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_011178897.1	3	MetaCyc: PWY-5697;MetaCyc: PWY-5698;KEGG: 00230+3.5.2.5	"Allantoin degradation to ureidoglycolate I (urea producing)";"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Purine metabolism"
XP_028895952.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011191689.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1	"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Purine metabolism"
XP_011186639.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_011188625.2	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_011194965.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_011177429.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_054086096.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054081761.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_054081666.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054084694.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_011182465.1	6	KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"Circadian Clock";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_011193337.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_011188534.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_011192201.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_028893611.2	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_011195561.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011190156.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_011194833.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_011176604.1	3	MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen synthesis"
XP_011176805.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Ion channel transport"
XP_011185752.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72165	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway"
XP_028895811.2	33	Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-168325	"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Mitotic Prometaphase";"Separation of Sister Chromatids";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis"
XP_011183903.2	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054086136.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_028898408.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_028899835.2	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_028899285.1	12	Reactome: R-HSA-70263;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-6142;KEGG: 00010+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13	"Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism"
XP_054090686.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_011189185.2	7	KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043;MetaCyc: PWY-7255;KEGG: 00480+6.3.2.2;MetaCyc: PWY-6840;Reactome: R-HSA-5578999;Reactome: R-HSA-174403	"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Glutathione metabolism";"Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling"
XP_028902228.2	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_054085908.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_011185926.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_011182877.2	29	MetaCyc: PWY-5480;KEGG: 00625+1.1.1.1;MetaCyc: PWY-6802;MetaCyc: PWY-7013;KEGG: 00260+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-6333;KEGG: 00626+1.1.1.1;MetaCyc: PWY-7396;MetaCyc: PWY-7111;MetaCyc: PWY-7118;MetaCyc: PWY-5076;MetaCyc: PWY-5082;MetaCyc: PWY-6342;MetaCyc: PWY-5078;MetaCyc: PWY-5751;KEGG: 00830+1.1.1.1;KEGG: 00982+1.1.1.1;MetaCyc: PWY-6587;KEGG: 00980+1.1.1.1;MetaCyc: PWY-6313;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5057;MetaCyc: PWY-3162;KEGG: 00071+1.1.1.1;KEGG: 00592+1.1.1.1;MetaCyc: PWY-6871;MetaCyc: PWY-5079;KEGG: 00350+1.1.1.1	"Pyruvate fermentation to ethanol I";"Chloroalkane and chloroalkene degradation";"Salidroside biosynthesis";"(S)-propane-1,2-diol degradation";"Glycine, serine and threonine metabolism";"Pyruvate fermentation to ethanol II";"Acetaldehyde biosynthesis I";"Naphthalene degradation";"Butanol and isobutanol biosynthesis (engineered)";"Pyruvate fermentation to isobutanol (engineered)";"Chitin degradation to ethanol";"L-leucine degradation III";"L-methionine degradation III";"Noradrenaline and adrenaline degradation";"L-isoleucine degradation II";"Phenylethanol biosynthesis";"Retinol metabolism";"Drug metabolism - cytochrome P450";"Pyruvate fermentation to ethanol III";"Metabolism of xenobiotics by cytochrome P450";"Serotonin degradation";"Glycolysis / Gluconeogenesis";"L-valine degradation II";"L-tryptophan degradation V (side chain pathway)";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"3-methylbutanol biosynthesis (engineered)";"L-phenylalanine degradation III";"Tyrosine metabolism"
XP_011190500.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_011187886.2	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
XP_054083932.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054086799.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054090241.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_011181309.2	15	Reactome: R-HSA-176034;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-2173796;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-674695	"Interactions of Tat with host cellular proteins";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events"
XP_011191081.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_011186031.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_011189476.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_054087594.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_011191356.1	3	MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662	"Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_011183397.1	3	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis"
XP_054088088.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054089858.1	4	Reactome: R-HSA-8950505;Reactome: R-HSA-3371453;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of HSF1-mediated heat shock response";"Cristae formation";"Mitochondrial protein import"
XP_054088819.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_011178095.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_054089949.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054081366.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011192905.2	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_011186339.1	5	MetaCyc: PWY-5269;KEGG: 00564+2.7.8.5;MetaCyc: PWY-5668;MetaCyc: PWY-7817;Reactome: R-HSA-1483148	"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PG"
XP_054089998.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011196648.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135	"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER"
XP_011192504.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_011195414.2	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_011189051.2	7	KEGG: 00030+3.1.1.31;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6;Reactome: R-HSA-71336;MetaCyc: PWY-6906;MetaCyc: PWY-6855;MetaCyc: PWY-8004	"Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Pentose phosphate pathway";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"Entner-Doudoroff pathway I"
XP_011195002.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_011196907.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_011193927.1	5	Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32;KEGG: 00620+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00010+4.1.1.32	"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis"
XP_011179877.2	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_011186421.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_028900535.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011182911.2	14	Reactome: R-HSA-4419969;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-1483213;Reactome: R-HSA-75109;KEGG: 00565+3.1.3.4;MetaCyc: PWY-7782;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1483191;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4	"Depolymerisation of the Nuclear Lamina";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of PE";"Triglyceride biosynthesis";"Ether lipid metabolism";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Synthesis of PC";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism"
XP_054088806.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054083486.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_054090422.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_011183094.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_011188828.1	14	KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-975634;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7417	"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Plasmalogen degradation";"Retinoid metabolism and transport";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)"
XP_011196381.1	6	MetaCyc: PWY-6368;MetaCyc: PWY-6580;MetaCyc: PWY-6367;KEGG: 00562+3.1.3.64+3.1.3.95;KEGG: 04070+3.1.3.64+3.1.3.95;Reactome: R-HSA-1660499	"3-phosphoinositide degradation";"Phosphatidylinositol biosynthesis I (bacteria)";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane"
XP_054085751.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_011192827.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054082499.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_011196061.1	14	MetaCyc: PWY-6453;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-7589	"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_011177245.1	5	Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695	"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation"
XP_011191796.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_011183478.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_028897051.2	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_011194723.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_011186009.2	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_011193805.2	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_054081970.1	9	Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-3928662;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"EPHB-mediated forward signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation"
XP_011178153.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_011191093.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_011196973.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054090096.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_011178716.2	3	Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER"
XP_054088343.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_054081268.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_011194787.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_011187197.2	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_028900648.2	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054090793.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_011187379.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_011196934.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054087913.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_028901377.1	12	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-450408;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-9010553;Reactome: R-HSA-72662;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-166208	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"Regulation of expression of SLITs and ROBOs";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"ISG15 antiviral mechanism";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling"
XP_011184318.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_011189136.2	15	Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-5358752;Reactome: R-HSA-3769402;Reactome: R-HSA-5358749;Reactome: R-HSA-5358751;Reactome: R-HSA-5467333;Reactome: R-HSA-5467337;Reactome: R-HSA-5689896	"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"T41 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"S37 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases"
XP_011184902.2	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_054082608.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054090635.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_028899886.2	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_054087411.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054082187.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011195756.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_011184538.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054091135.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_054083571.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_054086386.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_054081696.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_054084664.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054081791.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054085661.1	4	Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I"
XP_054088698.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011182495.1	14	Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5656121	"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Polymerase switching";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLI"
XP_011195550.1	17	MetaCyc: PWY-7179;KEGG: 00240+2.4.2.1;MetaCyc: PWY-4202;Reactome: R-HSA-6798695;MetaCyc: PWY-6608;Reactome: R-HSA-74217;MetaCyc: PWY-6620;MetaCyc: PWY-5695;MetaCyc: PWY-5532;Reactome: R-HSA-74259;MetaCyc: PWY-6627;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6644;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;MetaCyc: PWY-6609	"Purine deoxyribonucleosides degradation I";"Pyrimidine metabolism";"Arsenate detoxification I (mammalian)";"Neutrophil degranulation";"Guanosine nucleotides degradation III";"Purine salvage";"Guanine and guanosine salvage";"Inosine 5'-phosphate degradation";"Nucleoside and nucleotide degradation (archaea)";"Purine catabolism";"Salinosporamide A biosynthesis";"Nicotinate and nicotinamide metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III"
XP_028893458.2	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_054090162.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_028902244.2	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_011194855.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_011182936.1	10	MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861	"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_011184042.2	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_011187285.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_011187835.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054086359.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_011194654.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_011179482.1	5	MetaCyc: PWY-7536;KEGG: 00860+2.3.1.37;MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00260+2.3.1.37	"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Glycine, serine and threonine metabolism"
XP_011182372.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054081425.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011191760.2	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_011192014.2	7	Reactome: R-HSA-446193;MetaCyc: PWY-6385;MetaCyc: PWY-6470;Reactome: R-HSA-5633231;MetaCyc: PWY-5265;MetaCyc: PWY-6471;KEGG: 00550+2.4.1.227	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis"
XP_011187338.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_011189799.2	10	MetaCyc: PWY-6537;MetaCyc: PWY-4321;MetaCyc: PWY-5022;MetaCyc: PWY-6535;KEGG: 00650+2.6.1.19;KEGG: 00640+2.6.1.19;KEGG: 00410+2.6.1.19;Reactome: R-HSA-916853;KEGG: 00250+2.6.1.19;MetaCyc: PWY-6536	"4-aminobutanoate degradation II";"L-glutamate degradation IV";"4-aminobutanoate degradation V";"4-aminobutanoate degradation I";"Butanoate metabolism";"Propanoate metabolism";"beta-Alanine metabolism";"Degradation of GABA";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation III"
XP_011184210.2	56	Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-69017	"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6"
XP_011195086.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_028901677.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011195165.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_011178279.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_011180907.2	42	KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6944;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6583;MetaCyc: PWY-5109;MetaCyc: PWY-1361;MetaCyc: PWY-7779;MetaCyc: PWY-6435;MetaCyc: PWY-5138;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00360+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-7778;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-7606;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-5177;MetaCyc: PWY-6883;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-7216;MetaCyc: PWY-6945;MetaCyc: PWY-7654;KEGG: 00410+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00592+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00623+1.1.1.35;KEGG: 00627+4.2.1.17	"Butanoate metabolism";"Propanoate metabolism";"Androstenedione degradation";"Fatty acid elongation";"Limonene and pinene degradation";"Pyruvate fermentation to butanol I";"Fermentation to 2-methylbutanoate";"Benzoyl-coa degradation I (aerobic)";"Methyl tert-butyl ether degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Geraniol degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Phenylalanine metabolism";"Tryptophan metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"2-methylpropene degradation";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"Spodoptera littoralis pheromone biosynthesis";"Glutaryl-coa degradation";"Pyruvate fermentation to butanol II (engineered)";"Lysine degradation";"Pyruvate fermentation to hexanol (engineered)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"beta-Alanine metabolism";"Benzoate degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"alpha-Linolenic acid metabolism";"Valine, leucine and isoleucine degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Caprolactam degradation";"Fatty acid salvage";"Toluene degradation";"Aminobenzoate degradation"
XP_011187679.1	15	Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-8853884	"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX"
XP_011180648.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054086353.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_054090515.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_011193123.1	9	MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00710+1.2.1.12;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-6901;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70263	"Glycerol degradation to butanol";"Glycolysis";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Gluconeogenesis"
XP_011176469.2	22	Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-5358752;Reactome: R-HSA-141444	"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"RAF activation";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_054081182.1	29	Reactome: R-HSA-6804756;Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-110320;Reactome: R-HSA-5358606;Reactome: R-HSA-176187;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-3371453;Reactome: R-HSA-69166;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-3371511;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-912446	"Regulation of TP53 Activity through Phosphorylation";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"Translesion Synthesis by POLH";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Activation of ATR in response to replication stress";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of HSF1-mediated heat shock response";"Removal of the Flap Intermediate";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HSF1 activation";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Meiotic recombination"
XP_054084629.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054088901.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011196083.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054089112.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_028898027.2	3	Reactome: R-HSA-913709;Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"O-linked glycosylation of mucins";"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_011186655.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_011181074.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_011192704.2	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_011188345.1	3	KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_028898669.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_011187638.1	30	Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-400253;Reactome: R-HSA-69231;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-2894862;Reactome: R-HSA-2644607;Reactome: R-HSA-5607761;Reactome: R-HSA-917937;Reactome: R-HSA-180534;Reactome: R-HSA-2644606;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-1170546;Reactome: R-HSA-5676590;Reactome: R-HSA-5684264;Reactome: R-HSA-174113;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-2122947	"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Circadian Clock";"Cyclin D associated events in G1";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Iron uptake and transport";"Vpu mediated degradation of CD4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Prolactin receptor signaling";"NIK-->noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_011178630.2	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_054087523.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule"
XP_011196437.1	4	KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_011182244.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_011182767.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_054088349.1	26	Reactome: R-HSA-918233;Reactome: R-HSA-9013508;Reactome: R-HSA-3371568;Reactome: R-HSA-201722;Reactome: R-HSA-9617629;Reactome: R-HSA-933541;Reactome: R-HSA-5621575;Reactome: R-HSA-1989781;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-8866907;Reactome: R-HSA-2122947;Reactome: R-HSA-5617472;Reactome: R-HSA-3134973;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-9614657;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-3899300;Reactome: R-HSA-3214847;Reactome: R-HSA-1368082	"TRAF3-dependent IRF activation pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"Attenuation phase";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of FOXO transcriptional activity by acetylation";"TRAF6 mediated IRF7 activation";"CD209 (DC-SIGN) signaling";"PPARA activates gene expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SUMOylation of transcription cofactors";"HATs acetylate histones";"RORA activates gene expression"
XP_054087227.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646	"Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification"
XP_011190633.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68962	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of the pre-replicative complex"
XP_054088403.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_054089270.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054085361.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054090528.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_011188432.2	9	Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779	"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_011184935.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_011191099.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_011189873.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-5689880	"Ovarian tumor domain proteases";"Ub-specific processing proteases"
XP_054087906.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_011183726.1	7	KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.16	"Cysteine and methionine metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Glutathione metabolism"
XP_054087587.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_011191822.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_054086781.1	3	Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_011190700.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_011182962.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_054085732.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_054082493.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_011185560.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054082541.1	13	Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802955;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674135;KEGG: 05170+2.7.11.1	"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"mTOR signaling pathway";"Thermogenesis";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Human cytomegalovirus infection";"Human papillomavirus infection";"MAP2K and MAPK activation";"Human immunodeficiency virus 1 infection"
XP_028896071.2	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_011187176.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_011176852.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054084538.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_054087525.1	6	Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_054089221.1	24	Reactome: R-HSA-190840;Reactome: R-HSA-6811434;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-983189	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Aggrephagy";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Gap junction assembly";"RHO GTPases activate IQGAPs";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Kinesins"
XP_054081610.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_054081652.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054085273.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7	"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis"
XP_011195616.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011182282.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054088405.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_011195857.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054082626.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_011185024.1	8	MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-8086	"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Propanoate metabolism";"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_054087673.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_028899764.2	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_054084126.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054091178.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011194714.2	8	KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;Reactome: R-HSA-5173105	"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"O-linked glycosylation"
XP_054084325.1	5	Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;MetaCyc: PWY-6855;MetaCyc: PWY-6906	"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Chitin derivatives degradation"
XP_028896924.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_054082495.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_011176911.1	3	MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892	"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)"
XP_054090678.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_011177053.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-186763;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921;Reactome: R-HSA-8849471	"EPHB-mediated forward signaling";"Downstream signal transduction";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"
XP_054087071.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_054083667.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011190162.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_011182742.2	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_011186297.2	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_011188266.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_028893796.1	10	MetaCyc: PWY-5844;MetaCyc: PWY-5849;MetaCyc: PWY-5890;MetaCyc: PWY-5839;KEGG: 00130+2.1.1.163;Reactome: R-HSA-2142789;MetaCyc: PWY-7996;MetaCyc: PWY-5892;MetaCyc: PWY-5895;MetaCyc: PWY-5891	"Menaquinol-9 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-7 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-12 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-11 biosynthesis"
XP_054081967.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_028898365.2	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011179608.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054090217.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_054089879.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_011193125.1	8	KEGG: 04660+3.1.3.16;MetaCyc: PWY-5668;KEGG: 05235+3.1.3.16;KEGG: 00564+3.1.3.27;MetaCyc: PWY-7817;MetaCyc: PWY-5269;KEGG: 04658+3.1.3.16;Reactome: R-HSA-1483148	"T cell receptor signaling pathway";"Cardiolipin biosynthesis I";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Th1 and Th2 cell differentiation";"Synthesis of PG"
XP_054090513.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_011187289.1	13	MetaCyc: PWY-5913;MetaCyc: PWY-7384;KEGG: 00020+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-8086;KEGG: 00720+4.2.1.2;Reactome: R-HSA-71403;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6969	"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_054088490.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011196578.2	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_054086355.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_054086156.1	9	Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-975634	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport"
XP_011181035.1	5	Reactome: R-HSA-168638;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-171007	"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"DSCAM interactions";"p38MAPK events"
XP_011176877.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_011180457.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_011194886.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_011196085.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_054089914.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054089569.1	12	Reactome: R-HSA-2644606;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_011191516.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054090052.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_054084318.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_054091590.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_011196271.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054082054.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011187798.1	7	MetaCyc: PWY-6363;MetaCyc: PWY-4702;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_054082400.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_011179007.2	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
XP_011195245.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011192520.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_054087292.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_011181660.2	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_054090987.1	15	Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398	"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"Ca2+ pathway"
XP_011188349.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_011189270.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_011180426.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_011181249.3	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011195055.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_054083520.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011195443.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054090506.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_011195309.2	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_011187046.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054087880.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_054089563.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-456926	"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_011191082.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_054087638.1	9	KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7533;Reactome: R-HSA-156590;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18	"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis";"Glutathione conjugation";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450"
XP_054089417.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054084070.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054091133.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_011187564.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054090242.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_054091908.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054083931.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011186599.2	4	Reactome: R-HSA-351202;KEGG: 00270+4.1.1.50;MetaCyc: PWY-6834;KEGG: 00330+4.1.1.50	"Metabolism of polyamines";"Cysteine and methionine metabolism";"Spermidine biosynthesis III";"Arginine and proline metabolism"
XP_011187283.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_054090964.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_011182308.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054082326.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054090519.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_028896334.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_011179851.1	10	Reactome: R-HSA-2453902;Reactome: R-HSA-2453864;MetaCyc: PWY-5691;MetaCyc: PWY-7394;MetaCyc: PWY-7849;Reactome: R-HSA-3000171;KEGG: 00230+3.5.2.17;Reactome: R-HSA-6798695;Reactome: R-HSA-977225;Reactome: R-HSA-975634	"The canonical retinoid cycle in rods (twilight vision)";"Retinoid cycle disease events";"Urate conversion to allantoin I";"Urate conversion to allantoin II";"Urate conversion to allantoin III";"Non-integrin membrane-ECM interactions";"Purine metabolism";"Neutrophil degranulation";"Amyloid fiber formation";"Retinoid metabolism and transport"
XP_054091099.1	9	KEGG: 00720+6.4.1.1;KEGG: 00620+6.4.1.1;Reactome: R-HSA-3371599;Reactome: R-HSA-70263;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-8086;Reactome: R-HSA-196780;MetaCyc: PWY-6146	"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism"
XP_011187587.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_054083621.1	19	Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-8856828;Reactome: R-HSA-3000484;Reactome: R-HSA-3000480;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-8957275;Reactome: R-HSA-202733;Reactome: R-HSA-8866423;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-8964038;Reactome: R-HSA-8963888;Reactome: R-HSA-975634;Reactome: R-HSA-5686938;Reactome: R-HSA-8856825	"Platelet sensitization by LDL";"Chylomicron remodeling";"Clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"Scavenging by Class A Receptors";"VLDL clearance";"Scavenging by Class B Receptors";"LDL remodeling";"Scavenging by Class H Receptors";"Post-translational protein phosphorylation";"Cell surface interactions at the vascular wall";"VLDL assembly";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"LDL clearance";"Chylomicron assembly";"Retinoid metabolism and transport";"Regulation of TLR by endogenous ligand";"Cargo recognition for clathrin-mediated endocytosis"
XP_011187675.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_011178361.1	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS I - Hurler syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_011186686.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_054086127.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_011184410.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-196108	"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Pregnenolone biosynthesis"
XP_011179168.2	5	Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382	"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex"
XP_028899549.2	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_011181002.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_028898975.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_011191095.1	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8854691;KEGG: 04660+2.7.10.2	"Interleukin-4 and Interleukin-13 signaling";"Interleukin-20 family signaling";"T cell receptor signaling pathway"
XP_054090421.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_054081199.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_011182912.2	14	Reactome: R-HSA-75109;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-1483213;MetaCyc: PWY-8051;Reactome: R-HSA-1483191;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-7782;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053	"Triglyceride biosynthesis";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of PE";"Anandamide biosynthesis I";"Synthesis of PC";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II"
XP_054084618.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011180501.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_011194184.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_011184813.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_028895459.1	22	Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558	"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_054081736.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_011178069.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_011181583.2	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_011179308.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054085392.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_028898665.2	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_011179576.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_054087915.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_011188901.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_011193541.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_011194450.2	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_011177922.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_011182756.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054081620.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_011179605.1	7	Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Nephrin family interactions";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_011187339.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_011180137.2	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_054086358.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_054088699.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011178402.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_011195626.2	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_011177164.2	4	Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_011192330.1	7	Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897	"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes"
XP_054084315.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_011196819.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011193001.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_011181415.1	14	Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-674695	"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events"
XP_011195803.1	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
XP_054081741.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_011180775.1	11	Reactome: R-HSA-2029482;Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5663213;Reactome: R-HSA-8940973;Reactome: R-HSA-525793;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-69231;Reactome: R-HSA-8939236;Reactome: R-HSA-983231	"Regulation of actin dynamics for phagocytic cup formation";"Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway";"RHO GTPases Activate WASPs and WAVEs";"RUNX2 regulates osteoblast differentiation";"Myogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"Cyclin D associated events in G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Factors involved in megakaryocyte development and platelet production"
XP_028894290.2	9	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-110314	"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex"
XP_028896569.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_011181038.1	5	Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-380972	"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Macroautophagy";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_011191094.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_011179761.2	24	KEGG: 05163+2.7.11.1;Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-1257604;Reactome: R-HSA-114604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-5607764;KEGG: 04714+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-9634635;Reactome: R-HSA-5218921;Reactome: R-HSA-444257;Reactome: R-HSA-202424;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;Reactome: R-HSA-5218920;Reactome: R-HSA-5625740	"Human cytomegalovirus infection";"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Activation of AKT2";"PIP3 activates AKT signaling";"GPVI-mediated activation cascade";"Relaxin signaling pathway";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"CLEC7A (Dectin-1) signaling";"Thermogenesis";"G beta:gamma signalling through PI3Kgamma";"Estrogen-stimulated signaling through PRKCZ";"VEGFR2 mediated cell proliferation";"RSK activation";"Downstream TCR signaling";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"VEGFR2 mediated vascular permeability";"RHO GTPases activate PKNs"
XP_011181265.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054084471.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054090743.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_011192716.1	6	Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_028896680.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054084535.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_054087528.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_011191540.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_011187378.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_011187506.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_054086801.1	3	Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events"
XP_054081269.1	13	Reactome: R-HSA-4341670;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;Reactome: R-HSA-4085001;KEGG: 00052+3.2.1.23;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;Reactome: R-HSA-2206308;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096	"Defective NEU1 causes sialidosis";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Sialic acid metabolism";"Galactose metabolism";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"MPS IV - Morquio syndrome B";"Other glycan degradation";"HS-GAG degradation"
XP_054090046.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_054088408.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_054083946.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_054090523.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_011190373.1	4	KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614	"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage"
XP_011178827.2	3	Reactome: R-HSA-975577;Reactome: R-HSA-2022854;Reactome: R-HSA-913709	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis";"O-linked glycosylation of mucins"
XP_011190141.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_011196431.2	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_011179113.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_028894409.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_011184578.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_054089924.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_011191043.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_011185233.1	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_054090675.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_054090587.1	7	Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171	"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions"
XP_011177295.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646	"Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification"
XP_054082498.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_011193443.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012	"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_011187700.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_011191641.1	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_011187191.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_011183596.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_011179922.2	14	KEGG: 00630+2.1.2.1;KEGG: 00680+2.1.2.1;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-2161;MetaCyc: PWY-5497;MetaCyc: PWY-3841;MetaCyc: PWY-1622;KEGG: 00460+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-3661-1;MetaCyc: PWY-2201;Reactome: R-HSA-196757	"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Glycine, serine and threonine metabolism";"Glycine betaine degradation I";"Folate polyglutamylation";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Formaldehyde assimilation I (serine pathway)";"Cyanoamino acid metabolism";"One carbon pool by folate";"Photorespiration ";"Glycine betaine degradation II (mammalian)";"Folate transformations I";"Metabolism of folate and pterines"
XP_054082309.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_054089969.1	16	Reactome: R-HSA-5602498;Reactome: R-HSA-209543;Reactome: R-HSA-5603041;Reactome: R-HSA-9020702;Reactome: R-HSA-6811558;Reactome: R-HSA-1236974;Reactome: R-HSA-975155;Reactome: R-HSA-1810476;Reactome: R-HSA-166058;Reactome: R-HSA-5602680;Reactome: R-HSA-3134963;Reactome: R-HSA-975138;Reactome: R-HSA-5603037;Reactome: R-HSA-975110;Reactome: R-HSA-1257604;Reactome: R-HSA-975871	"MyD88 deficiency (TLR2/4)";"p75NTR recruits signalling complexes";"IRAK4 deficiency (TLR2/4)";"Interleukin-1 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ER-Phagosome pathway";"MyD88 dependent cascade initiated on endosome";"RIP-mediated NFkB activation via ZBP1";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 deficiency (TLR5)";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"IRAK4 deficiency (TLR5)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"PIP3 activates AKT signaling";"MyD88 cascade initiated on plasma membrane"
XP_011179783.2	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_011192531.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_011177805.1	3	Reactome: R-HSA-75105;MetaCyc: PWY-5996;MetaCyc: PWY-5987	"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Sorgoleone biosynthesis"
XP_028902113.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011195767.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_011191098.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_011192703.1	6	MetaCyc: PWY-5651;MetaCyc: PWY-7765;Reactome: R-HSA-71240;MetaCyc: PWY-6309;MetaCyc: PWY-7717;KEGG: 00380+1.14.13.9	"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan metabolism"
XP_011181073.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_054090529.1	1	Reactome: R-HSA-525793	"Myogenesis"
YP_004891167.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_011179547.2	10	Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23	"HS-GAG degradation";"Other glycan degradation";"Galactose metabolism";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism"
XP_054091850.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism"
XP_028901143.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011183817.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_011193124.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_028901542.1	7	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism"
XP_054081567.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054081413.1	7	Reactome: R-HSA-2173796;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-212436	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Generic Transcription Pathway"
XP_011187010.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_054083716.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_011181961.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011179106.1	12	MetaCyc: PWY-7901;MetaCyc: PWY-1187;MetaCyc: PWY-601;MetaCyc: PWY-6842;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6309;MetaCyc: PWY-801;KEGG: 00380+2.6.1.7;KEGG: 00450+4.4.1.13;Reactome: R-HSA-71240;MetaCyc: PWY-6936;MetaCyc: PWY-2821	"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tryptophan";"Glutathione-mediated detoxification II";"Cysteine and methionine metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Homocysteine and cysteine interconversion";"Tryptophan metabolism";"Selenocompound metabolism";"Tryptophan catabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine"
XP_028898668.2	9	Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_011181517.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_028893905.1	5	Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-8856825	"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis"
XP_011193609.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_011186450.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_054088110.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_011181463.2	16	Reactome: R-HSA-5603037;Reactome: R-HSA-5602680;Reactome: R-HSA-975138;Reactome: R-HSA-3134963;Reactome: R-HSA-975871;Reactome: R-HSA-975110;Reactome: R-HSA-1257604;Reactome: R-HSA-209543;Reactome: R-HSA-9020702;Reactome: R-HSA-5603041;Reactome: R-HSA-5602498;Reactome: R-HSA-1810476;Reactome: R-HSA-166058;Reactome: R-HSA-1236974;Reactome: R-HSA-6811558;Reactome: R-HSA-975155	"IRAK4 deficiency (TLR5)";"MyD88 deficiency (TLR5)";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"PIP3 activates AKT signaling";"p75NTR recruits signalling complexes";"Interleukin-1 signaling";"IRAK4 deficiency (TLR2/4)";"MyD88 deficiency (TLR2/4)";"RIP-mediated NFkB activation via ZBP1";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"ER-Phagosome pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88 dependent cascade initiated on endosome"
XP_011184887.2	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_011176511.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_011182086.2	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_011197110.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_011177890.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_054091905.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_028899183.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_054087635.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_054084628.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054090411.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054088693.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011193616.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_011184665.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011197012.2	6	Reactome: R-HSA-196780;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15	"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism"
XP_011180649.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_011182305.1	57	Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-6798695	"Separation of Sister Chromatids";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neutrophil degranulation"
XP_054082730.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_054088091.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-5610787	"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (z) signalling events";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state"
XP_028896873.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_011189227.2	10	MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842	"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification II"
XP_011183560.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_028895566.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_011187333.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054084103.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_011190046.1	17	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-75035;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-69473;Reactome: R-HSA-8953750;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1433557;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"G2/M DNA damage checkpoint";"Transcriptional Regulation by E2F6";"mTOR signaling pathway";"Signaling by SCF-KIT";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_054090880.1	13	Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52	"CS/DS degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_011178740.2	4	MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;Reactome: R-HSA-71737	"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation";"Pyrophosphate hydrolysis"
XP_011192751.2	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054090802.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054082605.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_011190523.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72702	"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition"
XP_054087242.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011195448.2	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-432722	"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis"
XP_011185023.2	7	Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.67;MetaCyc: PWY-6352;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;KEGG: 00562+2.7.1.67;MetaCyc: PWY-6351	"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_011182562.1	6	KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11	"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis"
XP_011185202.2	4	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
XP_011190743.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_054088954.1	10	MetaCyc: PWY-922;Reactome: R-HSA-1989781;KEGG: 00900+2.3.3.10;KEGG: 00072+2.3.3.10;MetaCyc: PWY-6174;MetaCyc: PWY-7571;MetaCyc: PWY-7391;MetaCyc: PWY-7524;KEGG: 00650+2.3.3.10;KEGG: 00280+2.3.3.10	"Mevalonate pathway I";"PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Synthesis and degradation of ketone bodies";"Mevalonate pathway II (archaea)";"Ferrichrome A biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Butanoate metabolism";"Valine, leucine and isoleucine degradation"
XP_011185688.1	9	Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-69183	"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Processive synthesis on the lagging strand"
XP_054084319.1	9	Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_011190122.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_028902128.2	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_011189835.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011180779.1	11	Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-983231;Reactome: R-HSA-8939236;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890;Reactome: R-HSA-525793;Reactome: R-HSA-8940973	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling";"Myogenesis";"RUNX2 regulates osteoblast differentiation"
XP_054091540.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9649948	"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants"
XP_011178107.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011187288.1	13	MetaCyc: PWY-7254;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-561;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2;Reactome: R-HSA-71403;KEGG: 00720+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-6728	"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle"
XP_011178280.2	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_011184624.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054088440.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054088894.1	6	KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-7900;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_054091641.1	16	Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-426496;Reactome: R-HSA-1912408	"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation"
XP_054088695.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011191932.2	8	MetaCyc: PWY-5740;KEGG: 00051+4.2.1.47;MetaCyc: PWY-7573;MetaCyc: PWY-66;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5739;Reactome: R-HSA-6787639;MetaCyc: PWY-5738	"GDP-L-colitose biosynthesis";"Fructose and mannose metabolism";"GDP-mycosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"Amino sugar and nucleotide sugar metabolism";"GDP-D-perosamine biosynthesis";"GDP-fucose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis"
XP_011191704.3	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_011194009.1	4	KEGG: 00510+3.2.1.114;MetaCyc: PWY-7920;KEGG: 00513+3.2.1.114;MetaCyc: PWY-7426	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_011178546.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_028897948.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011191175.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_011183531.1	5	Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-532668;Reactome: R-HSA-8957275;Reactome: R-HSA-901042	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation";"Calnexin/calreticulin cycle"
XP_028893641.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054081428.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054087519.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_054091043.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_011183703.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_011181406.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_011179163.2	57	Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-6798695	"Ub-specific processing proteases";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation"
XP_054087421.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_011193059.2	20	MetaCyc: PWY-7338;MetaCyc: PWY-6920;MetaCyc: PWY-7606;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;MetaCyc: PWY-5136;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-7291;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6	"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism"
XP_028894893.2	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_054090679.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_011177299.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14	"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis"
XP_011192705.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_011181620.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054091179.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011189211.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897	"mTOR signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes"
XP_011176837.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_028900734.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_011187515.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_011188907.2	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054081143.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2"
XP_011196231.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011194301.1	10	Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-9018519;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-167161	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation"
XP_011180146.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_011177721.2	14	Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725	"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_011182997.2	3	Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312	"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1"
XP_054081415.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054085402.1	11	Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-383280;Reactome: R-HSA-2151201;Reactome: R-HSA-212436;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108	"Circadian Clock";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Nuclear Receptor transcription pathway";"Transcriptional activation of mitochondrial biogenesis";"Generic Transcription Pathway";"Estrogen-dependent gene expression";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_028898157.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_011190878.2	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_028898460.2	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_054084533.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054086004.1	4	Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_011187635.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_054084606.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_011187834.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_054084701.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011190375.1	4	KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I"
XP_054086262.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054086450.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_011192015.1	4	Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2;MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2	"Selenocysteine synthesis";"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_054089965.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054081198.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_028896077.1	6	KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920	"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)"
XP_054083971.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_011188050.2	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_028902163.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054082106.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_011196210.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054090338.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_011183330.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_054091916.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_011181346.1	1	Reactome: R-HSA-419771	"Opsins"
XP_011195168.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_011191990.1	2	Reactome: R-HSA-8981607;Reactome: R-HSA-203615	"Intracellular oxygen transport";"eNOS activation"
XP_054087929.1	10	Reactome: R-HSA-3214847;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042	"HATs acetylate histones";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_054084446.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_011179603.1	7	Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Nephrin family interactions";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_011184615.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex"
XP_054088382.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_054083596.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054090518.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_054091557.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_011196573.2	8	Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-164378	"Factors involved in megakaryocyte development and platelet production";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"DARPP-32 events";"PKA activation in glucagon signalling"
XP_054088062.1	8	Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-5673001	"Long-term potentiation";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade"
XP_011196935.2	7	Reactome: R-HSA-1474151;Reactome: R-HSA-69205;MetaCyc: PWY-6614;KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3;MetaCyc: PWY-3841;Reactome: R-HSA-196757	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"G1/S-Specific Transcription";"Tetrahydrofolate biosynthesis";"One carbon pool by folate";"Folate biosynthesis";"Folate transformations II (plants)";"Metabolism of folate and pterines"
XP_054081776.1	4	MetaCyc: PWY-7119;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662	"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_054091909.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011195604.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156827	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_054088457.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054084420.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_011181413.1	5	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-3214815	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"HDACs deacetylate histones"
XP_011190749.1	3	Reactome: R-HSA-1358803;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011194582.1	7	MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-1268020;Reactome: R-HSA-2151201;Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2	"ATP biosynthesis";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis";"Cristae formation";"Photosynthesis"
XP_054087639.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_054082294.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
YP_004891170.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_028895897.2	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_011188348.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_054083817.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_028900935.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_011184553.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011193002.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054081742.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_054087655.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_054088887.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_054082556.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_054084472.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_011190995.2	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_011180140.2	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_011179144.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_011184152.2	3	Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999	"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
XP_011197132.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011179762.2	24	Reactome: R-HSA-2871837;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-1257604;KEGG: 04151+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-389357;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5607764;Reactome: R-HSA-392451;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-5218921;Reactome: R-HSA-444257;Reactome: R-HSA-354192;Reactome: R-HSA-202424;Reactome: R-HSA-5625740;Reactome: R-HSA-2730905;Reactome: R-HSA-5218920	"FCERI mediated NF-kB activation";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Activation of AKT2";"PIP3 activates AKT signaling";"PI3K-Akt signaling pathway";"GPVI-mediated activation cascade";"CD28 dependent PI3K/Akt signaling";"Relaxin signaling pathway";"Regulation of TP53 Degradation";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"CLEC7A (Dectin-1) signaling";"G beta:gamma signalling through PI3Kgamma";"Thermogenesis";"Estrogen-stimulated signaling through PRKCZ";"VEGFR2 mediated cell proliferation";"RSK activation";"Integrin signaling";"Downstream TCR signaling";"RHO GTPases activate PKNs";"Role of LAT2/NTAL/LAB on calcium mobilization";"VEGFR2 mediated vascular permeability"
XP_054084849.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_011181721.2	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_054081200.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_011188502.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_011179225.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054089212.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054088823.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_054088864.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_011178401.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_054085255.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_028895475.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_054091474.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430	"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling"
XP_054083647.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054089170.1	6	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-76005	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+"
XP_028899925.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_011195428.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011186675.1	24	Reactome: R-HSA-500657;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-9009391;Reactome: R-HSA-428930;Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-8964315;Reactome: R-HSA-456926;Reactome: R-HSA-400042;Reactome: R-HSA-420092;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-163359;Reactome: R-HSA-202040;Reactome: R-HSA-418217;Reactome: R-HSA-418597;Reactome: R-HSA-381676;Reactome: R-HSA-6814122	"Presynaptic function of Kainate receptors";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Extra-nuclear estrogen signaling";"Thromboxane signalling through TP receptor";"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"G beta:gamma signalling through BTK";"Thrombin signalling through proteinase activated receptors (PARs)";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-type ligand receptors";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Glucagon signaling in metabolic regulation";"G-protein activation";"G beta:gamma signalling through PLC beta";"G alpha (z) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_028899267.2	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_054086928.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_028896765.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054085175.1	4	Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963	"Pyrimidine catabolism";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I"
XP_011186906.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_011188437.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_011179218.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054087765.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011192612.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_011180614.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_011186523.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054082561.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_054090236.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_011186564.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_011192258.2	5	Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379	"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events"
XP_011186046.1	8	Reactome: R-HSA-917977;MetaCyc: PWY-7980;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"ATP biosynthesis";"ROS and RNS production in phagocytes";"Oxidative phosphorylation";"Insulin receptor recycling";"Photosynthesis";"Ion channel transport";"Amino acids regulate mTORC1"
XP_028901118.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054091830.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011189184.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_054086638.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_011181784.2	3	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-8951664	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Neddylation"
XP_011186913.1	11	MetaCyc: PWY-7254;MetaCyc: PWY-6549;KEGG: 00720+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6728	"TCA cycle VII (acetate-producers)";"L-glutamine biosynthesis III";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Ethylene biosynthesis V (engineered)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle"
XP_011191617.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_011183897.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054081604.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport"
XP_011195961.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054081805.1	10	Reactome: R-HSA-196757;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-1722;MetaCyc: PWY-6613;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030	"Metabolism of folate and pterines";"Folate transformations I";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III"
XP_011186749.1	13	Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-8964038;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-182218;Reactome: R-HSA-8856828;Reactome: R-HSA-167590;Reactome: R-HSA-177504;Reactome: R-HSA-3928665;Reactome: R-HSA-2132295	"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"LDL clearance";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD8 Down-regulation";"Clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Retrograde neurotrophin signalling";"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation"
XP_011188934.1	14	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-5620924;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-1632852;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Aggrephagy";"Mitotic Prometaphase";"Intraflagellar transport";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Macroautophagy";"RHO GTPases Activate Formins"
XP_028895692.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011189447.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054088166.1	3	Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_011176976.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054089855.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_011181962.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_028901541.1	22	MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7727;MetaCyc: PWY-7728;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7053;KEGG: 00062+4.2.1.134;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7592;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7049;MetaCyc: PWY-5353;MetaCyc: PWY-7726;MetaCyc: PWY-6958;MetaCyc: PWY-7602;MetaCyc: PWY-7606;MetaCyc: PWY-5080	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I"
XP_054089654.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_011185916.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_011193418.2	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054085990.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_028898076.2	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_011194782.2	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_011179530.2	3	Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-525793	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"Myogenesis"
XP_011194964.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011192532.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_011181657.2	3	Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_011184586.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_011184344.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725	"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_011188056.1	32	Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-6803529;Reactome: R-HSA-72165;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-72203;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167162	"mRNA Capping";"HIV Transcription Initiation";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"FGFR2 alternative splicing";"mRNA Splicing - Minor Pathway";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape"
XP_054085045.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_054091068.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054086673.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_011176756.1	8	MetaCyc: PWY-7400;MetaCyc: PWY-5;KEGG: 00220+6.3.4.5;Reactome: R-HSA-70635;KEGG: 00250+6.3.4.5;MetaCyc: PWY-4983;MetaCyc: PWY-5154;MetaCyc: PWY-4984	"L-arginine biosynthesis IV (archaebacteria)";"Canavanine biosynthesis";"Arginine biosynthesis";"Urea cycle";"Alanine, aspartate and glutamate metabolism";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle"
XP_054081890.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054083566.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_054088829.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_054090944.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_011180460.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054088092.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-164378	"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Purine metabolism";"G alpha (z) signalling events";"G alpha (s) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation in glucagon signalling"
XP_011182074.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-8876198;Reactome: R-HSA-1445148;Reactome: R-HSA-8873719;Reactome: R-HSA-1660499	"Neutrophil degranulation";"RAB GEFs exchange GTP for GDP on RABs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB geranylgeranylation";"Synthesis of PIPs at the plasma membrane"
XP_011193229.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_011182148.2	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_011186261.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_011193425.2	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_011183777.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011177810.2	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_054090412.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011179487.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_011182377.1	20	Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-6804756	"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation"
XP_028898466.1	7	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00983+2.7.4.14;MetaCyc: PWY-7176;KEGG: 00240+2.7.4.14	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism"
XP_028897673.2	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_011188089.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases"
XP_028895275.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054091642.1	16	Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569	"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_028895361.2	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_011193487.2	5	Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20	"Neutrophil degranulation";"Glycerolipid metabolism";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_011178201.2	8	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-8953750	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6"
XP_028897122.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054086906.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054089167.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-114516	"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation"
XP_011179229.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011197091.3	3	MetaCyc: PWY-1801;KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590	"Formaldehyde oxidation II (glutathione-dependent)";"Methane metabolism";"Glutathione conjugation"
XP_054082585.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_011177428.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_054081114.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_011182561.1	6	MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11	"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis"
XP_011195419.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_011191726.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_011184778.2	29	Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-69166;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-3371453;Reactome: R-HSA-5696397;Reactome: R-HSA-3108214;Reactome: R-HSA-110320;Reactome: R-HSA-5358606;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-3371511;Reactome: R-HSA-6783310;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-69473	"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Removal of the Flap Intermediate";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Translesion Synthesis by POLH";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"HSF1 activation";"Fanconi Anemia Pathway";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint"
XP_028901717.2	7	KEGG: 00195+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-2151201;Reactome: R-HSA-8949613;Reactome: R-HSA-163210;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2	"Photosynthesis";"Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis";"Cristae formation";"Formation of ATP by chemiosmotic coupling";"ATP biosynthesis";"Oxidative phosphorylation"
XP_011192752.2	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054087032.1	1	Reactome: R-HSA-376172	"DSCAM interactions"
XP_011191280.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011180754.2	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054083102.1	10	Reactome: R-HSA-432720;Reactome: R-HSA-182971;Reactome: R-HSA-5689880;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-917729;Reactome: R-HSA-9635644;Reactome: R-HSA-8856828;Reactome: R-HSA-9636383	"Lysosome Vesicle Biogenesis";"EGFR downregulation";"Ub-specific processing proteases";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Inhibition of membrane repair";"Clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion"
XP_011190607.1	4	KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558	"Cysteine and methionine metabolism";"Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine"
XP_054085286.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-163359	"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"G alpha (z) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation"
XP_011179696.2	3	KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2	"Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation"
XP_054086227.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_011185201.2	4	Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_011178508.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport"
XP_011189072.2	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_054087659.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_011182229.1	2	Reactome: R-HSA-1461973;Reactome: R-HSA-1462054	"Defensins";"Alpha-defensins"
XP_054081803.1	10	KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-6613;Reactome: R-HSA-196757;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-7909	"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines";"Folate transformations I";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)"
XP_011177722.2	14	MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5080	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I"
XP_011187441.2	3	Reactome: R-HSA-174403;MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9	"Glutathione synthesis and recycling";"Gamma-glutamyl cycle";"Glutathione metabolism"
XP_011176494.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054085401.1	11	Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-383280;Reactome: R-HSA-2151201;Reactome: R-HSA-212436;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108	"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Nuclear Receptor transcription pathway";"Transcriptional activation of mitochondrial biogenesis";"Generic Transcription Pathway";"Estrogen-dependent gene expression";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_054088083.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054089853.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054082592.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_011177637.2	5	Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines"
XP_028896422.2	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_011176941.2	6	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_011189462.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_011177219.2	3	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_028899150.2	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_054085179.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011180933.2	2	MetaCyc: PWY-5344;KEGG: 00270+2.3.1.31	"L-homocysteine biosynthesis";"Cysteine and methionine metabolism"
XP_011195075.1	5	MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556;Reactome: R-HSA-392154	"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis";"Arginine and proline metabolism";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase"
XP_054087422.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_011181187.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_011189291.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011179561.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_011190447.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011194267.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_011189212.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_028900067.1	10	Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-917729;Reactome: R-HSA-9635644;Reactome: R-HSA-8856828;Reactome: R-HSA-9636383;Reactome: R-HSA-432720;Reactome: R-HSA-182971;Reactome: R-HSA-5689880;Reactome: R-HSA-8875360	"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Inhibition of membrane repair";"Clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"Lysosome Vesicle Biogenesis";"EGFR downregulation";"Ub-specific processing proteases";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_011188864.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054092044.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_054081788.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011177265.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_054088759.1	8	Reactome: R-HSA-9627069;Reactome: R-HSA-6798695;Reactome: R-HSA-8953750;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-6803207	"Regulation of the apoptosome activity";"Neutrophil degranulation";"Transcriptional Regulation by E2F6";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_054083972.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2644606	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_011178771.1	33	Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-69273;Reactome: R-HSA-112382;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-69202;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-69656;Reactome: R-HSA-76042;Reactome: R-HSA-69231;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-8939236;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-6796648	"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"Cyclin E associated events during G1/S transition";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin D associated events in G1";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes"
XP_054084240.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_054088753.1	23	Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-500657;Reactome: R-HSA-8964315;Reactome: R-HSA-456926;Reactome: R-HSA-418555;Reactome: R-HSA-416482;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-9009391;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-420092;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-6814122;Reactome: R-HSA-418597;Reactome: R-HSA-418217;Reactome: R-HSA-202040	"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through BTK";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (s) signalling events";"G alpha (12/13) signalling events";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"Extra-nuclear estrogen signaling";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Glucagon-type ligand receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (z) signalling events";"G beta:gamma signalling through PLC beta";"G-protein activation"
XP_011188829.1	14	Reactome: R-HSA-1482788;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5	"Acyl chain remodelling of PC";"Retinoid metabolism and transport";"Ether lipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Glycerophospholipid metabolism"
XP_011181851.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011196251.1	4	Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs"
XP_011188092.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-418594	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"G alpha (i) signalling events"
XP_054091960.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_054088056.1	12	KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-451308;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-399719	"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Long-term potentiation";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors"
XP_011196649.1	4	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_054089886.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_054084586.1	7	KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-2301;MetaCyc: PWY-6363;Reactome: R-HSA-1855183	"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Phytate degradation I";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_011196290.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_011193039.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054081816.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_054089948.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054088818.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_011182414.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_028895063.2	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_054088089.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011189764.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_028899378.1	4	MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20	"Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism"
XP_054086261.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_011192095.2	6	Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-176187	"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress"
XP_011176562.2	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_011192207.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054087653.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_054086798.1	3	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis"
XP_011181576.2	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
XP_011191811.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_028895817.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_011188868.2	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_011195320.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054086529.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_011180668.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_054088825.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_028897913.2	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_054088624.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_028902229.2	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_011179223.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_028899421.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011192362.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_028893889.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011179527.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_011178850.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_054088061.1	12	Reactome: R-HSA-451308;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-438066	"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Long-term potentiation";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_011194288.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011192000.2	3	Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_011185990.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054088381.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-975577;Reactome: R-HSA-913709	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation";"O-linked glycosylation of mucins"
XP_011186518.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER"
XP_011196997.2	13	Reactome: R-HSA-5578775;Reactome: R-HSA-2871809;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-381676;Reactome: R-HSA-983695;Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-139853;Reactome: R-HSA-4086398;Reactome: R-HSA-1489509	"Ion homeostasis";"FCERI mediated Ca+2 mobilization";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"Elevation of cytosolic Ca2+ levels";"Ca2+ pathway";"DAG and IP3 signaling"
XP_011190904.1	19	MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;Reactome: R-HSA-163765;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5172;MetaCyc: PWY-7384;KEGG: 00020+2.3.3.8;Reactome: R-HSA-6798695;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;KEGG: 00720+2.3.3.8;Reactome: R-HSA-75105;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-5537;Reactome: R-HSA-71403	"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Acetyl-coa biosynthesis III (from citrate)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Neutrophil degranulation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Fatty acyl-CoA biosynthesis";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)"
XP_011191678.2	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_054082819.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054087453.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_054082088.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_054091744.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_011191706.3	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_054088896.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_054088989.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_054081958.1	4	KEGG: 00564+3.1.1.7;Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Glycerophospholipid metabolism";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_028896905.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_054091563.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054091524.1	7	KEGG: 00600+2.4.1.80;MetaCyc: PWY-7841;MetaCyc: PWY-7836;MetaCyc: PWY-7839;MetaCyc: PWY-7838;MetaCyc: PWY-5129;Reactome: R-HSA-1660662	"Sphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Glycosphingolipid metabolism"
XP_054087322.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054089908.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_054084947.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_054083768.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_028896676.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_028895489.2	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_011185544.2	7	Reactome: R-HSA-500753;MetaCyc: PWY-5686;MetaCyc: PWY-7790;KEGG: 00240+2.4.2.10;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10	"Pyrimidine biosynthesis";"UMP biosynthesis I";"UMP biosynthesis II";"Pyrimidine metabolism";"Pyrimidine metabolism";"UMP biosynthesis III";"Drug metabolism - other enzymes"
XP_054082806.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_011192855.2	1	Reactome: R-HSA-525793	"Myogenesis"
XP_011184640.2	10	Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-2197563;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-8941856	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"RUNX3 regulates NOTCH signaling"
XP_011186327.2	3	Reactome: R-HSA-975577;Reactome: R-HSA-2022854;Reactome: R-HSA-913709	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis";"O-linked glycosylation of mucins"
XP_011186971.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_054086234.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011179815.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011196711.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_011194014.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_011189940.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_011179614.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_011187862.1	18	MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416	"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_054088956.1	6	Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;MetaCyc: PWY-7285;MetaCyc: PWY-6829;Reactome: R-HSA-6785470;MetaCyc: PWY-7286	"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"Methylwyosine biosynthesis";"Trna methylation (yeast)";"tRNA processing in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_011185945.1	57	Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-532668;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-8939902	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity"
XP_054084007.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_011189731.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054086330.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_011182707.1	4	KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_054089048.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_054084522.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054086709.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_011193668.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_028894310.2	10	Reactome: R-HSA-400206;Reactome: R-HSA-983231;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692	"Regulation of lipid metabolism by PPARalpha";"Factors involved in megakaryocyte development and platelet production";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity"
XP_011186689.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011179980.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054088961.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_011192982.2	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_028900921.1	4	Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_011192543.2	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_028900846.2	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_011196074.3	5	Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937072	"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_054085949.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_011182815.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011183718.2	5	KEGG: 00860+4.2.1.24;Reactome: R-HSA-189451;MetaCyc: PWY-5188;Reactome: R-HSA-6798695;MetaCyc: PWY-5189	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)"
XP_028902157.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_011184054.2	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_011192801.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_011180429.2	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_011190258.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054085009.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_011191112.1	13	Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-5628897;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-6804757;Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724	"mTOR signalling";"HSF1-dependent transactivation";"TP53 Regulates Metabolic Genes";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of TP53 Degradation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"Macroautophagy";"Regulation of PTEN gene transcription"
XP_011179881.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_028893470.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054091602.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030;Reactome: R-HSA-110357	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1"
XP_054086630.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054091838.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_054091221.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_011182070.2	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_028902231.2	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_011192250.2	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_011179314.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_011177979.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054085601.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011197079.2	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_011184340.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_028900218.2	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_011187455.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_028900610.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_054082104.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_011187720.2	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_011191031.2	2	Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054085943.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_011182496.2	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_011196309.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_011187836.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054086006.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_054090841.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_028899772.2	8	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5689880;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Ub-specific processing proteases";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_011183859.2	8	MetaCyc: PWY-6609;MetaCyc: PWY-6611;Reactome: R-HSA-5683826;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;MetaCyc: PWY-7179	"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Surfactant metabolism";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Purine metabolism";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I"
XP_011190174.1	10	KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11;KEGG: 00332+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;Reactome: R-HSA-8964539	"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism"
XP_011186683.2	6	MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-6922;KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981;Reactome: R-HSA-8964539	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism"
XP_011178807.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_054086475.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_011177103.1	7	MetaCyc: PWY-4984;MetaCyc: PWY-46;MetaCyc: PWY-6922;MetaCyc: PWY-31;KEGG: 00220+3.5.3.1;KEGG: 00330+3.5.3.1;Reactome: R-HSA-70635	"Urea cycle";"Putrescine biosynthesis III";"L-Ndelta-acetylornithine biosynthesis";"Canavanine degradation";"Arginine biosynthesis";"Arginine and proline metabolism";"Urea cycle"
XP_011176800.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702	"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition"
XP_011194342.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054082296.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_011187401.2	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_011181780.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054088927.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054084950.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_011184058.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_011193974.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560	"T cell receptor signaling pathway";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"Triglyceride catabolism"
XP_054086311.1	1	Reactome: R-HSA-419771	"Opsins"
XP_054085595.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054088206.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011193623.2	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_011176775.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054088722.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_054084717.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_011181648.2	16	Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-174178	"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_054088542.1	4	Reactome: R-HSA-499943;Reactome: R-HSA-2161541;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054083594.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141	"Heme biosynthesis";"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_054081774.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_028900984.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_011197143.2	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_054082813.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation"
XP_011186069.2	8	Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69166	"Polymerase switching";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate"
XP_028893569.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011177083.2	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054084114.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_011192008.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011182329.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011177578.1	12	MetaCyc: PWY-5873;MetaCyc: PWY-5857;MetaCyc: PWY-5855;KEGG: 00130+1.14.99.60;MetaCyc: PWY-7233;MetaCyc: PWY-5871;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-6708;MetaCyc: PWY-7230;MetaCyc: PWY-5856	"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (prokaryotic)"
XP_054081644.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054086473.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_028901733.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_011179664.2	3	Reactome: R-HSA-5694530;Reactome: R-HSA-948021;Reactome: R-HSA-204005	"Cargo concentration in the ER";"Transport to the Golgi and subsequent modification";"COPII-mediated vesicle transport"
XP_011188337.1	11	Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-68952	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation"
XP_028894195.2	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_011177868.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_054086817.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054085593.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_054082815.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_011197145.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054085297.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_011195825.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011192188.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_011183291.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_011191524.1	2	Reactome: R-HSA-389957;Reactome: R-HSA-8953750	"Prefoldin mediated transfer of substrate to CCT/TriC";"Transcriptional Regulation by E2F6"
XP_011196550.2	5	Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490	"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins"
XP_054087572.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_054087134.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054089000.1	7	KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;Reactome: R-HSA-5628897	"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes"
XP_054091374.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_028901426.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011176893.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_028898053.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_011185161.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011185276.2	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_054089926.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_028896341.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_011193017.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_011182819.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_054088810.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_011191267.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_028894837.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_011188989.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_011196512.2	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_054089940.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_011184007.1	52	Reactome: R-HSA-72163;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-5578749;Reactome: R-HSA-76071;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-6782135;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-6781823;Reactome: R-HSA-5601884;Reactome: R-HSA-167158;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-76066;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-167152;Reactome: R-HSA-73980;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-5250924;Reactome: R-HSA-73776;Reactome: R-HSA-1834949;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-76061;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-72203;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-73863	"mRNA Splicing - Major Pathway";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of TC-NER Pre-Incision Complex";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Termination";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Processing of Capped Intron-Containing Pre-mRNA";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination"
XP_011191302.1	5	MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)"
XP_011184742.1	4	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_011193157.2	33	Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-141444	"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_011186685.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_011195818.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011186577.2	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_011176953.1	4	MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49	"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Pentose phosphate pathway"
XP_011187771.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054084248.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054082460.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054081780.1	4	MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23	"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Sphingolipid metabolism"
XP_011182758.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_011181208.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_028898165.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054081226.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_028894425.2	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_028897389.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_011177619.1	4	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281;Reactome: R-HSA-2408557;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Cytosolic tRNA aminoacylation"
XP_028901382.1	12	Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-450408;Reactome: R-HSA-975956;Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72662	"ISG15 antiviral mechanism";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"
XP_054089752.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_054084597.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_011182296.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_011188038.2	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32	"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism"
XP_011194235.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_054089957.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_011182813.1	25	Reactome: R-HSA-8939246;Reactome: R-HSA-8939236;Reactome: R-HSA-8941284;Reactome: R-HSA-8939256;Reactome: R-HSA-8931987;Reactome: R-HSA-8939242;Reactome: R-HSA-8941858;Reactome: R-HSA-8936459;Reactome: R-HSA-8951911;Reactome: R-HSA-8941326;Reactome: R-HSA-8939243;Reactome: R-HSA-8949275;Reactome: R-HSA-8939247;Reactome: R-HSA-8939245;Reactome: R-HSA-8935964;Reactome: R-HSA-8877330;Reactome: R-HSA-8951936;Reactome: R-HSA-8940973;Reactome: R-HSA-8939902;Reactome: R-HSA-8941332;Reactome: R-HSA-9616222;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-8878166;Reactome: R-HSA-8941333	"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"Regulation of RUNX3 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX3 regulates RUNX1-mediated transcription";"RUNX2 regulates bone development";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates expression of components of tight junctions";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX3 regulates p14-ARF";"RUNX2 regulates osteoblast differentiation";"Regulation of RUNX2 expression and activity";"RUNX2 regulates genes involved in cell migration";"Transcriptional regulation of granulopoiesis";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Transcriptional regulation by RUNX2";"RUNX2 regulates genes involved in differentiation of myeloid cells"
XP_011195580.2	1	Reactome: R-HSA-3000178	"ECM proteoglycans"
XP_011176507.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-1445148	"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_011181578.3	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
XP_054091488.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_054088831.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_011195246.2	6	Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68949	"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Orc1 removal from chromatin"
XP_054086438.1	3	Reactome: R-HSA-3214815;Reactome: R-HSA-427413;Reactome: R-HSA-390522	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression";"Striated Muscle Contraction"
XP_011188722.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_054087397.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011178582.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054085728.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_011193614.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_011185127.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_028900791.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_011189566.2	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_011186888.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_054089135.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054085599.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-6798695;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Neutrophil degranulation";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_011176779.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054091565.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054090532.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_011177755.2	9	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-110314	"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex"
XP_011188194.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902	"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation"
XP_054082534.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011186920.1	2	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
XP_011187201.1	6	MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;MetaCyc: PWY-622;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_011191748.2	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_028893633.2	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_011185765.2	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_011184604.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_011187622.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_054091674.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199	"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation"
XP_054087667.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_011185077.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011177739.2	5	KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5653	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_054090705.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_011184415.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_011178270.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_011180756.2	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_011179813.3	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_028894119.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602	"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_011183568.2	3	Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426	"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_054084521.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054085284.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-163359	"G alpha (z) signalling events";"G alpha (s) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation"
XP_011191066.2	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_011191544.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_011187861.1	18	Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482925	"Acyl chain remodelling of PS";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PG"
XP_011190273.2	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_011180053.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011191185.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054088657.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-6807505;Reactome: R-HSA-983168	"Protein ubiquitination";"RNA polymerase II transcribes snRNA genes";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054087885.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_011189683.1	16	Reactome: R-HSA-5693548;Reactome: R-HSA-3214847;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-9018519;Reactome: R-HSA-2559586;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-201722;Reactome: R-HSA-5693565	"Sensing of DNA Double Strand Breaks";"HATs acetylate histones";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Estrogen-dependent gene expression";"DNA Damage/Telomere Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Formation of the beta-catenin:TCF transactivating complex";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_054086904.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_011182901.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011189842.2	4	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_011179554.1	10	KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916	"Galactose metabolism";"Other glycan degradation";"HS-GAG degradation";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation"
XP_011192915.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_054082146.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_054083525.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6811438	"RAB geranylgeranylation";"Intra-Golgi traffic"
XP_011185270.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012	"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_011185217.2	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_054087910.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_054090790.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_054089392.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_011187018.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011194043.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-390471;Reactome: R-HSA-983168	"Neddylation";"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011179882.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054089279.1	7	Reactome: R-HSA-2029485;KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561;MetaCyc: PWY-7039;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;KEGG: 00565+3.1.4.4	"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG";"Synthesis of PA";"Ether lipid metabolism"
XP_054090817.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011192373.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_054086650.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054091858.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_054092046.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_011196970.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_011192802.1	10	MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;Reactome: R-HSA-1483166	"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA"
XP_011190552.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_054088784.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054091016.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_011196268.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011181319.1	11	Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-68962	"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Activation of the pre-replicative complex"
XP_011185052.2	8	KEGG: 04151+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_028894390.1	10	MetaCyc: PWY-6142;Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00010+5.3.1.1;KEGG: 00562+5.3.1.1;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00710+5.3.1.1;KEGG: 00051+5.3.1.1	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Inositol phosphate metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism"
XP_011190709.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_054084419.1	3	Reactome: R-HSA-5632681;Reactome: R-HSA-525793;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Myogenesis";"Activation of SMO"
XP_054090473.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_028896910.2	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_054088962.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011179901.1	2	Reactome: R-HSA-4570571;Reactome: R-HSA-446193	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_054083518.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_054088125.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_028895549.2	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_028899771.2	8	Reactome: R-HSA-5689880;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518	"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2"
XP_011182416.1	56	Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5676590	"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling"
XP_054082645.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_054090842.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis"
XP_011190159.2	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_054085581.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054081979.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_011185031.2	5	Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000	"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of MAPK pathway";"RAF activation"
XP_054088357.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_011190531.1	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_011178674.1	8	Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5;MetaCyc: PWY-6556;MetaCyc: PWY-7181;Reactome: R-HSA-6798695;MetaCyc: PWY-7193;KEGG: 00240+3.5.4.5;MetaCyc: PWY-7199	"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides degradation";"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage"
XP_011183564.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_054091222.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_028902232.2	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_011194557.1	4	Reactome: R-HSA-446199;MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108;Reactome: R-HSA-4755583	"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)"
XP_011178147.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054082076.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-381038	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes"
XP_011190888.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054091601.1	5	Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-3108214	"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins"
XP_054089273.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011196396.2	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_054083638.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054088054.1	12	Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;MetaCyc: PWY-7221	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Long-term potentiation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis"
XP_054087520.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_054084346.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011191807.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_028897908.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054089685.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_054087367.1	18	KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1483166	"Arachidonic acid metabolism";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA"
XP_011184860.1	5	MetaCyc: PWY-5523;MetaCyc: PWY-7863;MetaCyc: PWY-6168;KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843	"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Roseoflavin biosynthesis";"Flavin biosynthesis III (fungi)";"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism"
XP_054081814.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_054088721.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_054090438.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_011192456.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011193345.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_011176902.2	1	Reactome: R-HSA-5676934	"Protein repair"
XP_011195240.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054085569.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_011179416.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_054088541.1	4	Reactome: R-HSA-499943;Reactome: R-HSA-2161541;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054091595.1	5	Reactome: R-HSA-110357;Reactome: R-HSA-5221030;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-3108214	"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins"
XP_054081103.1	9	MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_011181619.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011188947.2	9	Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-416476;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204	"PLC beta mediated events";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol"
XP_011180059.2	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_011188164.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_011180305.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_011182290.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011192673.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_028893854.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011191715.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation"
XP_054086312.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_028899850.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011188007.2	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011184213.2	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_011193738.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_028901681.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_028897957.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_011181663.2	17	Reactome: R-HSA-2871837;Reactome: R-HSA-9645460;Reactome: R-HSA-450302;Reactome: R-HSA-450321;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-5357956;Reactome: R-HSA-9014325;Reactome: R-HSA-937072;Reactome: R-HSA-937042;Reactome: R-HSA-4086398;Reactome: R-HSA-168638;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-975163;Reactome: R-HSA-445989;Reactome: R-HSA-202424	"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway";"activated TAK1 mediates p38 MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"TNFR1-induced NFkappaB signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex";"Ca2+ pathway";"NOD1/2 Signaling Pathway";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Downstream TCR signaling"
XP_054082398.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054082403.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054088866.1	11	Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-3000170;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-3560783;Reactome: R-HSA-202733	"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Syndecan interactions";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective B4GALT7 causes EDS, progeroid type";"Cell surface interactions at the vascular wall"
XP_011196429.2	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_011190656.2	17	KEGG: 00720+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-3371599;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5743;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-196780;Reactome: R-HSA-2426168;MetaCyc: PWY-6679;Reactome: R-HSA-200425;MetaCyc: PWY-6722;MetaCyc: PWY-4381;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1	"Carbon fixation pathways in prokaryotes";"Aflatoxin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Propanoate metabolism";"3-hydroxypropanoate cycle";"Pyruvate metabolism";"Glyoxylate assimilation";"Biotin transport and metabolism";"Activation of gene expression by SREBF (SREBP)";"Jadomycin biosynthesis";"Carnitine metabolism";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)"
XP_054091297.1	4	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_011189311.2	6	MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122	"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis"
XP_011194508.1	9	MetaCyc: PWY-5981;MetaCyc: PWY-6118;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7385;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902;Reactome: R-HSA-1483166	"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"Synthesis of PA"
XP_011177845.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_054084428.1	14	Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692	"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity"
XP_054091476.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430	"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling"
XP_011180498.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_011190596.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_011180449.1	52	Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-72203;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-76061;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-9018519;Reactome: R-HSA-73980;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-203927;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-5250924;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-5601884;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-168325;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-5578749;Reactome: R-HSA-76071;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-72163	"HIV Transcription Initiation";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Processing of Capped Intron-Containing Pre-mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Termination";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"MicroRNA (miRNA) biogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"Viral Messenger RNA Synthesis";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"mRNA Splicing - Major Pathway"
XP_054088576.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054090510.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_011183518.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_011191949.1	3	KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00230+1.7.3.3	"Caffeine metabolism";"Urate conversion to allantoin I";"Purine metabolism"
XP_011184215.2	5	Reactome: R-HSA-3134975;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-3249367	"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines"
XP_054082554.1	13	Reactome: R-HSA-8856828;Reactome: R-HSA-167590;Reactome: R-HSA-177504;Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-8856825;Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-8964038;Reactome: R-HSA-182218;Reactome: R-HSA-5140745	"Clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Retrograde neurotrophin signalling";"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1";"VLDLR internalisation and degradation";"LDL clearance";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2"
XP_028894115.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_028899094.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_011179345.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054090709.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_028899138.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_011184521.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_011189821.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_011193649.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054084371.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_028896704.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_011196039.2	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_054091945.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-211981;Reactome: R-HSA-211976;Reactome: R-HSA-8937144;Reactome: R-HSA-211945	"PPARA activates gene expression";"Xenobiotics";"Endogenous sterols";"Aryl hydrocarbon receptor signalling";"Phase I - Functionalization of compounds"
XP_011187772.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011176939.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_011184930.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_011185302.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513	"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_011186566.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_028896960.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_011189186.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_028897777.2	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_054082041.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_054087670.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_011185267.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011191497.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054086777.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_011188118.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_011184075.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_011196511.2	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_054091005.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054081613.1	12	MetaCyc: PWY-7411;MetaCyc: PWY-7902;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.94;Reactome: R-HSA-5368286;MetaCyc: PWY-6118;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7385;MetaCyc: PWY-5667	"Phosphatidate biosynthesis (yeast)";"Glucosylglycerol biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Mitochondrial translation initiation";"Glycerol-3-phosphate shuttle";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis I"
XP_028900309.2	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_011190870.2	4	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11;Reactome: R-HSA-2408557;Reactome: R-HSA-379716	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"Cytosolic tRNA aminoacylation"
XP_011185563.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_011188816.2	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_011186904.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_054089683.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_054089937.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_028896342.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_011187439.1	13	Reactome: R-HSA-3000157;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-186797;Reactome: R-HSA-1650814;Reactome: R-HSA-216083;Reactome: R-HSA-1442490;Reactome: R-HSA-2243919;Reactome: R-HSA-1474244;Reactome: R-HSA-3000178;Reactome: R-HSA-419037;Reactome: R-HSA-2214320;Reactome: R-HSA-3000171	"Laminin interactions";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Signaling by PDGF";"Collagen biosynthesis and modifying enzymes";"Integrin cell surface interactions";"Collagen degradation";"Crosslinking of collagen fibrils";"Extracellular matrix organization";"ECM proteoglycans";"NCAM1 interactions";"Anchoring fibril formation";"Non-integrin membrane-ECM interactions"
XP_011185569.1	10	Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-6804756	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation"
XP_028896402.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054084149.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011195501.2	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_011177047.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation"
XP_011193901.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054081619.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_054088187.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_054088832.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_011177559.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011180536.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_011177907.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_011191854.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_011185442.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72649	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation"
XP_011192568.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054081606.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_011182953.2	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_011195600.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_011188936.1	14	Reactome: R-HSA-1632852;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-5620924;Reactome: R-HSA-9646399;Reactome: R-HSA-68877	"Macroautophagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Intraflagellar transport";"Aggrephagy";"Mitotic Prometaphase"
XP_011183679.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_054082649.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_011176806.2	18	KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1483166	"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Synthesis of PA"
XP_054089751.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_011177648.2	3	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-159230	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA"
XP_011191441.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_011184567.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels"
XP_011191500.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764	"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination"
XP_011187384.1	18	KEGG: 00220+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-5913;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00950+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00710+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00250+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;KEGG: 00400+2.6.1.1	"Arginine biosynthesis";"Coenzyme M biosynthesis II";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism";"Sulfolactate degradation III";"Carbon fixation in photosynthetic organisms";"Novobiocin biosynthesis";"(R)-cysteate degradation";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis"
XP_054083283.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054090531.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_011178136.2	4	MetaCyc: PWY-7119;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662	"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_011187621.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_054083587.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054088448.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_011195426.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011187688.2	5	Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825	"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis"
XP_011190081.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_028898310.1	18	KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;MetaCyc: PWY-7783	"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Plasmalogen degradation"
XP_011184584.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_011187087.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011178528.2	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_011189884.1	44	Reactome: R-HSA-5673001;Reactome: R-HSA-5663213;Reactome: R-HSA-170968;Reactome: R-HSA-982772;Reactome: R-HSA-881907;Reactome: R-HSA-375165;Reactome: R-HSA-5654733;Reactome: R-HSA-1295596;Reactome: R-HSA-879415;Reactome: R-HSA-2559580;Reactome: R-HSA-162658;Reactome: R-HSA-8939211;Reactome: R-HSA-8940973;Reactome: R-HSA-2559585;Reactome: R-HSA-6802948;Reactome: R-HSA-202670;Reactome: R-HSA-9627069;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-445144;Reactome: R-HSA-6802952;Reactome: R-HSA-5654726;Reactome: R-HSA-2559582;Reactome: R-HSA-9635465;Reactome: R-HSA-8943724;Reactome: R-HSA-5675221;Reactome: R-HSA-5654727;Reactome: R-HSA-444257;Reactome: R-HSA-6811558;Reactome: R-HSA-9634638;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-2029482;Reactome: R-HSA-198753;Reactome: R-HSA-456926;Reactome: R-HSA-5674499;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-3371453;Reactome: R-HSA-5668599;Reactome: R-HSA-5654732;Reactome: R-HSA-2871796;Reactome: R-HSA-74749;Reactome: R-HSA-112409	"RAF/MAP kinase cascade";"RHO GTPases Activate WASPs and WAVEs";"Frs2-mediated activation";"Growth hormone receptor signaling";"Gastrin-CREB signalling pathway via PKC and MAPK";"NCAM signaling for neurite out-growth";"Negative regulation of FGFR4 signaling";"Spry regulation of FGF signaling";"Advanced glycosylation endproduct receptor signaling";"Oxidative Stress Induced Senescence";"Golgi Cisternae Pericentriolar Stack Reorganization";"ESR-mediated signaling";"RUNX2 regulates osteoblast differentiation";"Oncogene Induced Senescence";"Signaling by high-kinase activity BRAF mutants";"ERKs are inactivated";"Regulation of the apoptosome activity";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"Signal transduction by L1";"Signaling by BRAF and RAF fusions";"Negative regulation of FGFR1 signaling";"Senescence-Associated Secretory Phenotype (SASP)";"Suppression of apoptosis";"Regulation of PTEN gene transcription";"Negative regulation of MAPK pathway";"Negative regulation of FGFR2 signaling";"RSK activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of actin dynamics for phagocytic cup formation";"ERK/MAPK targets";"Thrombin signalling through proteinase activated receptors (PARs)";"Negative feedback regulation of MAPK pathway";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Regulation of HSF1-mediated heat shock response";"RHO GTPases Activate NADPH Oxidases";"Negative regulation of FGFR3 signaling";"FCERI mediated MAPK activation";"Signal attenuation";"RAF-independent MAPK1/3 activation"
XP_011184346.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_028902120.2	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway"
XP_054091130.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_011188054.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_054085565.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER"
XP_054087370.1	18	MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4	"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism"
XP_028896708.2	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054089560.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-456926	"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_054083743.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011181814.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_011185838.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011178581.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054091599.1	5	Reactome: R-HSA-110357;Reactome: R-HSA-5221030;Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-110328	"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_028899572.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011179466.2	18	Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-77075;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167160;Reactome: R-HSA-167238	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation"
XP_011182734.2	56	Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-382556	"Hedgehog ligand biogenesis";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport"
XP_011194155.3	3	KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757	"Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines"
XP_054082300.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_011181815.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054089960.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_054087842.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_011192217.1	5	Reactome: R-HSA-70171;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-6906	"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin derivatives degradation"
XP_028896101.2	6	MetaCyc: PWY-6606;KEGG: 00230+3.5.4.3;MetaCyc: PWY-7442;Reactome: R-HSA-74259;MetaCyc: PWY-5497;MetaCyc: PWY-6608	"Guanosine nucleotides degradation II";"Purine metabolism";"Drosopterin and aurodrosopterin biosynthesis";"Purine catabolism";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation III"
XP_054091886.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_011187006.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_054084418.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054082204.1	5	Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_011177432.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_011189977.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_054090520.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_011196406.2	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_011188115.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_054083506.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_028896361.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054083378.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054087101.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Aggrephagy";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_054083987.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_011190233.2	8	Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-8943724;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-212300	"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of PTEN gene transcription";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"PRC2 methylates histones and DNA"
XP_011194691.1	12	Reactome: R-HSA-9010553;Reactome: R-HSA-72662;Reactome: R-HSA-156827;Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-450408;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-1169408	"Regulation of expression of SLITs and ROBOs";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"L13a-mediated translational silencing of Ceruloplasmin expression";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"mTORC1-mediated signalling";"ISG15 antiviral mechanism"
XP_054091859.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_028894962.1	7	Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Nephrin family interactions";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_011190537.2	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_028898465.2	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_011187946.1	6	Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-191859	"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"snRNP Assembly"
XP_028894125.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011187821.2	17	Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-1221632;Reactome: R-HSA-6796648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-3371453;Reactome: R-HSA-6783310;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Meiotic synapsis";"TP53 Regulates Transcription of DNA Repair Genes";"Human papillomavirus infection";"Activation of ATR in response to replication stress";"Thermogenesis";"PI3K-Akt signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of HSF1-mediated heat shock response";"Fanconi Anemia Pathway";"Relaxin signaling pathway";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_028897138.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011187888.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_011184967.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054090740.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269	"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_028896937.1	7	Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1660499;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;Reactome: R-HSA-8856828	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Clathrin-mediated endocytosis"
XP_028896683.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054085794.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
YP_004891175.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_028899509.2	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_028896356.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_028897401.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_011176574.2	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_011189401.3	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_054082395.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_011194876.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011189029.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011189811.1	27	Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-168271	"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus"
XP_054082196.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_028893447.2	13	MetaCyc: PWY-6859;MetaCyc: PWY-7709;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7410;MetaCyc: PWY-7102;MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-5122;MetaCyc: PWY-7659;MetaCyc: PWY-6383;MetaCyc: PWY-7182	"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Bisabolene biosynthesis (engineered)";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Geranyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Linalool biosynthesis I"
XP_054086397.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_054081687.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_011178915.2	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_011181126.1	10	Reactome: R-HSA-913709;MetaCyc: PWY-7979;Reactome: R-HSA-4717374;Reactome: R-HSA-162699;MetaCyc: PWY-7921;Reactome: R-HSA-4719377;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7661;Reactome: R-HSA-4719360;MetaCyc: PWY-7922	"O-linked glycosylation of mucins";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Synthesis of dolichyl-phosphate mannose";"Protein O-mannosylation I (yeast)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"N-Glycan biosynthesis";"Protein N-glycosylation (Haloferax volcanii)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_054081108.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_011184652.1	56	Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-69017	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6"
XP_011177120.2	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_054088106.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_011178483.1	15	Reactome: R-HSA-1660499;Reactome: R-HSA-1433557;Reactome: R-HSA-912631;Reactome: R-HSA-8853659;Reactome: R-HSA-389357;Reactome: R-HSA-416476;Reactome: R-HSA-388841;Reactome: R-HSA-114604;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-9009391;Reactome: R-HSA-512988;Reactome: R-HSA-912526;Reactome: R-HSA-6811558;Reactome: R-HSA-1266695	"Synthesis of PIPs at the plasma membrane";"Signaling by SCF-KIT";"Regulation of signaling by CBL";"RET signaling";"CD28 dependent PI3K/Akt signaling";"G alpha (q) signalling events";"Costimulation by the CD28 family";"GPVI-mediated activation cascade";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Extra-nuclear estrogen signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interleukin receptor SHC signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-7 signaling"
XP_011180495.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8875656	"RAB geranylgeranylation";"MET receptor recycling"
XP_011177959.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_054083339.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011190402.2	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_011181140.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054081623.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_054081664.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_011176619.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054086094.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054082501.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054084100.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054089537.1	5	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241;MetaCyc: PWY-7782;Reactome: R-HSA-75896;KEGG: 00565+2.5.1.26	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"Ether lipid metabolism"
XP_028893491.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_011197053.2	14	MetaCyc: PWY-8053;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-8051;Reactome: R-HSA-75896;Reactome: R-HSA-9033241;MetaCyc: PWY-7587;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.42;Reactome: R-HSA-1483166;MetaCyc: PWY-7411	"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Peroxisomal protein import";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)"
XP_054082733.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_054085492.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_011184033.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_011183162.1	3	Reactome: R-HSA-5626978;Reactome: R-HSA-193681;Reactome: R-HSA-1660662	"TNFR1-mediated ceramide production";"Ceramide signalling";"Glycosphingolipid metabolism"
XP_011187685.2	1	Reactome: R-HSA-419771	"Opsins"
XP_054087971.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_011189087.2	14	Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569	"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_054087705.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_011180058.2	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_054083678.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011195558.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054088445.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_011190960.2	10	Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_054090321.1	8	Reactome: R-HSA-8950505;Reactome: R-HSA-6791055;MetaCyc: PWY-1861;KEGG: 00030+2.2.1.2;MetaCyc: PWY-5723;Reactome: R-HSA-71336;Reactome: R-HSA-6791462;Reactome: R-HSA-163754	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Rubisco shunt";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Insulin effects increased synthesis of Xylulose-5-Phosphate"
XP_054086134.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_054091545.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-9620244	"Ion homeostasis";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation"
XP_011176539.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011193472.2	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_011177893.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054090684.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_011189064.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054088113.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_054090439.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_011191072.2	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054081323.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_028895051.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_054089014.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_011191598.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054089402.1	3	KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048	"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG"
XP_054090952.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_011184423.1	15	Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-69473;Reactome: R-HSA-5685939;Reactome: R-HSA-5693568;Reactome: R-HSA-2559586;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693565	"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"G2/M DNA damage checkpoint";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"DNA Damage/Telomere Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_011195416.2	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054083639.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054091853.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_011179344.2	13	MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-6728	"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle"
XP_011190435.1	5	Reactome: R-HSA-8964539;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;MetaCyc: PWY-3341	"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)"
XP_011185197.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054081387.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011179559.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_011192700.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011193204.1	6	Reactome: R-HSA-1483166;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-4261;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3	"Synthesis of PA";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism"
XP_011190856.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054087596.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_011187510.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_028897916.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_054081978.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-7445	"Matairesinol biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation"
XP_011186891.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_011192923.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054083513.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011191117.2	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_028898877.1	6	MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433	"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_011192380.2	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_054081325.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_028898415.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_011188119.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_011193780.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054091855.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_054088536.1	4	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_011184712.2	11	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-380972	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Human papillomavirus infection";"FOXO-mediated transcription of cell death genes";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_011178794.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_011183421.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2	"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism"
XP_011196371.2	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_054087475.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011186094.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011176938.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_011180007.2	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_054083515.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011196038.2	6	MetaCyc: PWY-7820;KEGG: 00520+1.1.1.22;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7346;Reactome: R-HSA-173599;KEGG: 00053+1.1.1.22	"Teichuronic acid biosynthesis (B. subtilis 168)";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Formation of the active cofactor, UDP-glucuronate";"Ascorbate and aldarate metabolism"
XP_011180742.2	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_011180123.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_011193648.1	56	Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-174084	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_011190726.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_011187842.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764	"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination"
XP_011178675.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_028896065.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_028901477.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011183700.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054091040.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054086622.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_011197055.2	14	MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-6453;Reactome: R-HSA-75896;MetaCyc: PWY-7587;Reactome: R-HSA-9033241;KEGG: 00564+2.3.1.42;Reactome: R-HSA-1483166;MetaCyc: PWY-7411	"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Peroxisomal protein import";"Glycerophospholipid metabolism";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)"
XP_054082735.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_028895222.2	3	Reactome: R-HSA-418457;Reactome: R-HSA-4086398;Reactome: R-HSA-392517	"cGMP effects";"Ca2+ pathway";"Rap1 signalling"
XP_054086201.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_054088443.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054088309.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_011183519.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_011182062.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_011182300.1	4	Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48	"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes"
XP_011180499.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054084429.1	14	Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723	"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation"
XP_054092052.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_011187732.2	2	KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819	"Purine metabolism";"Vitamin B1 (thiamin) metabolism"
XP_054091543.1	19	Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-877300;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571	"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Interferon gamma signaling";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation"
XP_011195432.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011182160.2	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_054091026.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_054083528.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_028897622.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011196428.2	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_011177349.2	3	KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963;Reactome: R-HSA-947581	"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_011190367.1	12	KEGG: 00680+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00051+4.1.2.13;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00030+4.1.2.13;MetaCyc: PWY-7385;Reactome: R-HSA-70263	"Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis"
XP_054082399.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054090996.1	13	Reactome: R-HSA-445989;Reactome: R-HSA-9020702;Reactome: R-HSA-975163;Reactome: R-HSA-5607764;Reactome: R-HSA-168638;Reactome: R-HSA-937072;Reactome: R-HSA-937042;Reactome: R-HSA-9014325;Reactome: R-HSA-5357956;Reactome: R-HSA-450321;Reactome: R-HSA-450302;Reactome: R-HSA-9645460;Reactome: R-HSA-2871837	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"CLEC7A (Dectin-1) signaling";"NOD1/2 Signaling Pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"activated TAK1 mediates p38 MAPK activation";"Alpha-protein kinase 1 signaling pathway";"FCERI mediated NF-kB activation"
XP_011192528.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_011193348.1	6	Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_011190910.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-1660499	"Macroautophagy";"Synthesis of PIPs at the plasma membrane"
XP_011188605.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_054084352.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054087716.1	6	KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism"
YP_004891173.1	7	MetaCyc: PWY-6692;Reactome: R-HSA-611105;MetaCyc: PWY-5083;MetaCyc: PWY-3781;MetaCyc: PWY-4302;KEGG: 00190+7.1.1.2;Reactome: R-HSA-6799198	"Fe(II) oxidation";"Respiratory electron transport";"NAD/NADH phosphorylation and dephosphorylation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"Complex I biogenesis"
XP_011192581.2	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054087611.1	9	Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695	"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"MAP2K and MAPK activation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation"
XP_011189480.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_011192799.1	57	Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-68949	"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin"
XP_011178913.2	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_028900742.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_054081573.1	3	Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-6804760	"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation"
XP_054091598.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1"
XP_011184195.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_011178256.2	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_054081496.1	10	Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-2151209;Reactome: R-HSA-200425;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_028896709.2	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_011176825.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054086891.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011180493.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054091212.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_011183467.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_011178485.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_054088449.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_011179600.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054081625.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_054091462.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_054089474.1	8	MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;Reactome: R-HSA-5683826;MetaCyc: PWY-6609	"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Neutrophil degranulation";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Surfactant metabolism";"Adenine and adenosine salvage III"
XP_028896716.2	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_011182774.2	13	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553	"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs"
XP_011196956.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_011180129.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1"
XP_054082648.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_054088616.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_011183678.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_011190684.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_011190885.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_028899048.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_011182682.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_054083834.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_054081157.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_011188113.1	5	Reactome: R-HSA-5610787;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684	"Hedgehog 'off' state";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state"
XP_011184080.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_028896685.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_028896577.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_011181939.1	4	Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;Reactome: R-HSA-4719360;Reactome: R-HSA-162699	"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of dolichyl-phosphate mannose"
XP_011181296.2	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_011191545.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_028894123.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011190321.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-110314;Reactome: R-HSA-6783310	"Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway"
XP_011187661.2	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_028899766.2	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_011177754.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_011183943.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011179695.3	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_028893906.2	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054091833.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_028896362.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054087102.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Aggrephagy";"Mitotic Prometaphase";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_011180428.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054083032.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_011187822.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_028900213.2	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_011189504.2	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_011183183.1	4	KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism"
XP_011187174.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_011193669.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_028899560.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054084245.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_011195614.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011186688.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011177431.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_054082624.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_028899971.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_054086708.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_011177575.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_054081507.1	12	MetaCyc: PWY-1187;MetaCyc: PWY-7901;MetaCyc: PWY-601;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-801;MetaCyc: PWY-6309;Reactome: R-HSA-71240;KEGG: 00450+4.4.1.13;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6936;MetaCyc: PWY-2821	"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from tryptophan";"Cysteine and methionine metabolism";"Glutathione-mediated detoxification II";"Homocysteine and cysteine interconversion";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"Selenocompound metabolism";"Tryptophan metabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine"
XP_054089916.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_011189990.1	23	Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-9009391;Reactome: R-HSA-428930;Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-418555;Reactome: R-HSA-416482;Reactome: R-HSA-456926;Reactome: R-HSA-8964315;Reactome: R-HSA-500657;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-202040;Reactome: R-HSA-418597;Reactome: R-HSA-6814122;Reactome: R-HSA-381676;Reactome: R-HSA-400042;Reactome: R-HSA-420092;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-8964616	"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"Extra-nuclear estrogen signaling";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"G alpha (s) signalling events";"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through BTK";"Presynaptic function of Kainate receptors";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"G-protein activation";"G alpha (z) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42"
XP_011197074.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054089049.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_011181775.2	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_011191427.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011180038.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054081986.1	8	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_028898832.2	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_011180265.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054088074.1	2	Reactome: R-HSA-5576886;Reactome: R-HSA-1299308	"Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)"
XP_011190094.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_028895488.2	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_054081203.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_011193502.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation"
XP_011190401.2	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_011187407.1	58	Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-5689901;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603	"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"Metalloprotease DUBs";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Separation of Sister Chromatids";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases"
XP_054083769.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011188264.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_011188223.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_028897402.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_011193786.1	10	KEGG: 00010+1.2.4.1;Reactome: R-HSA-5389840;KEGG: 00020+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-70268	"Glycolysis / Gluconeogenesis";"Mitochondrial translation elongation";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Mitochondrial translation termination";"Mitochondrial translation initiation";"Pyruvate metabolism"
XP_054082089.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_054081959.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_054086154.1	9	Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801	"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD"
XP_011182151.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_028900570.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_054082818.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_011197148.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054088846.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_011188527.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition"
XP_011177088.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011184550.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764	"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination"
XP_011196444.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054089720.1	4	KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;MetaCyc: PWY-7437	"Other types of O-glycan biosynthesis";"HATs acetylate histones";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation"
XP_054087458.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_054090966.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054085725.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_011177813.2	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_054082083.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_011181649.2	6	MetaCyc: PWY-7077;MetaCyc: PWY-6906;Reactome: R-HSA-446210;KEGG: 00520+3.5.1.25;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7395	"N-acetyl-D-galactosamine degradation";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation"
XP_011178768.2	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_054085545.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054082220.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_011181394.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation"
XP_054082681.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_011182533.2	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_054082786.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011191634.1	6	KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-7900;Reactome: R-HSA-3878781;Reactome: R-HSA-3322077;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen storage disease type IV (GBE1)";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_054083763.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011186885.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_011186235.2	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_054084840.1	11	Reactome: R-HSA-6804756;Reactome: R-HSA-163680;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9614657	"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human immunodeficiency virus 1 infection";"FOXO-mediated transcription of cell death genes"
XP_011184059.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_054085491.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_011196912.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_011182665.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly"
XP_054090504.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_054082502.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_011187044.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011192353.1	6	Reactome: R-HSA-114516;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-5099900	"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4"
XP_054086025.1	11	Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_011182030.2	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_011191924.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_028897960.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_011187566.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_054089043.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_028893798.2	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_054082669.1	20	MetaCyc: PWY-5136;MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-6920;MetaCyc: PWY-7606;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-6837;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854	"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)"
XP_011182755.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_054083192.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054081734.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054085718.1	5	MetaCyc: PWY-5381;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-7761;Reactome: R-HSA-196807	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism"
XP_028901137.2	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_011186029.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_011180961.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011197144.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_011177084.1	7	Reactome: R-HSA-9029569;Reactome: R-HSA-3214842;Reactome: R-HSA-9018519;Reactome: R-HSA-8943724;Reactome: R-HSA-5625886;Reactome: R-HSA-983231;Reactome: R-HSA-3214815	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDMs demethylate histones";"Estrogen-dependent gene expression";"Regulation of PTEN gene transcription";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Factors involved in megakaryocyte development and platelet production";"HDACs deacetylate histones"
XP_011179574.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054085993.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011177323.1	16	KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-5538;KEGG: 00640+6.2.1.4;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5749;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;KEGG: 00020+6.2.1.4;MetaCyc: PWY-7384	"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Itaconate degradation";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_054090891.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011197078.2	33	MetaCyc: PWY-6333;KEGG: 00626+1.1.1.1;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5480;MetaCyc: PWY-5486;MetaCyc: PWY-6802;KEGG: 00260+1.1.1.1;MetaCyc: PWY-7013;MetaCyc: PWY-5082;MetaCyc: PWY-5076;MetaCyc: PWY-6342;KEGG: 00680+1.1.1.284;MetaCyc: PWY-7396;MetaCyc: PWY-7111;MetaCyc: PWY-7118;MetaCyc: PWY-3162;MetaCyc: PWY-5057;MetaCyc: PWY-6313;KEGG: 00010+1.1.1.1;KEGG: 00592+1.1.1.1;KEGG: 00071+1.1.1.1;MetaCyc: PWY-5751;KEGG: 00830+1.1.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-5078;KEGG: 00980+1.1.1.1;MetaCyc: PWY-6587;KEGG: 00982+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-1801;KEGG: 00350+1.1.1.1;MetaCyc: PWY-7798;MetaCyc: PWY-6871	"Acetaldehyde biosynthesis I";"Naphthalene degradation";"Chloroalkane and chloroalkene degradation";"Pyruvate fermentation to ethanol I";"Pyruvate fermentation to ethanol II";"Salidroside biosynthesis";"Glycine, serine and threonine metabolism";"(S)-propane-1,2-diol degradation";"L-methionine degradation III";"L-leucine degradation III";"Noradrenaline and adrenaline degradation";"Methane metabolism";"Butanol and isobutanol biosynthesis (engineered)";"Pyruvate fermentation to isobutanol (engineered)";"Chitin degradation to ethanol";"L-tryptophan degradation V (side chain pathway)";"L-valine degradation II";"Serotonin degradation";"Glycolysis / Gluconeogenesis";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Phenylethanol biosynthesis";"Retinol metabolism";"Ethanol oxidation";"L-isoleucine degradation II";"Metabolism of xenobiotics by cytochrome P450";"Pyruvate fermentation to ethanol III";"Drug metabolism - cytochrome P450";"L-phenylalanine degradation III";"Formaldehyde oxidation II (glutathione-dependent)";"Tyrosine metabolism";"Protein S-nitrosylation and denitrosylation";"3-methylbutanol biosynthesis (engineered)"
XP_054089401.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_028896957.1	3	Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23	"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism"
XP_054086435.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_011178117.2	4	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_054091485.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_011188970.2	13	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation"
XP_011177978.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_054086996.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_011177387.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011183949.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011180860.2	9	KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533;Reactome: R-HSA-156590;MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;KEGG: 00983+2.5.1.18	"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Glutathione conjugation";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Drug metabolism - other enzymes"
XP_054091839.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_011181146.2	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_011183422.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_028895914.2	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_011184711.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054088942.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054088287.1	3	Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_054089990.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_011180741.2	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_011181986.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054088360.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_011193574.1	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_054088414.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054088527.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_054090397.1	6	Reactome: R-HSA-114516;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-5099900	"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4"
XP_011192301.2	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_054087407.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_028898495.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054088264.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054083854.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_054091483.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_054086433.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_011190459.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054081955.1	4	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311;KEGG: 00564+3.1.1.7	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Glycerophospholipid metabolism"
XP_011195431.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054085247.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_011192189.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_054085723.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_054082085.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_011185859.1	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_011179056.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054091981.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_011196054.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_011182934.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148	"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054083765.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054089905.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_028900992.2	26	Reactome: R-HSA-3134973;Reactome: R-HSA-381340;Reactome: R-HSA-1234158;Reactome: R-HSA-400253;Reactome: R-HSA-2894862;Reactome: R-HSA-9614657;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-3899300;Reactome: R-HSA-1368082;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-3371568;Reactome: R-HSA-918233;Reactome: R-HSA-933541;Reactome: R-HSA-201722;Reactome: R-HSA-9617629;Reactome: R-HSA-210744;Reactome: R-HSA-1989781;Reactome: R-HSA-5621575;Reactome: R-HSA-8866907;Reactome: R-HSA-5617472;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408	"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression by Hypoxia-inducible Factor";"Circadian Clock";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"SUMOylation of transcription cofactors";"RORA activates gene expression";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Attenuation phase";"TRAF3-dependent IRF activation pathway";"TRAF6 mediated IRF7 activation";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"PPARA activates gene expression";"CD209 (DC-SIGN) signaling";"Activation of the TFAP2 (AP-2) family of transcription factors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation"
XP_028897367.2	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_011191046.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_054086621.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_011179315.2	18	MetaCyc: PWY-7222;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-6545	"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_011183686.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_011180465.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054089045.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_054091334.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054087647.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_011182328.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054084666.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011179363.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_011179324.1	6	KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"Circadian Clock";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_011180567.2	11	Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-163359	"G alpha (s) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation"
XP_054091211.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_011195387.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_011179083.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054083355.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054087551.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_011194937.1	4	Reactome: R-HSA-8875555;Reactome: R-HSA-186763;Reactome: R-HSA-8875656;Reactome: R-HSA-912631	"MET activates RAP1 and RAC1";"Downstream signal transduction";"MET receptor recycling";"Regulation of signaling by CBL"
XP_054086478.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_011179220.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011182669.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054091461.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402	"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex"
XP_054087612.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-9649948	"Platelet degranulation";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling downstream of RAS mutants"
XP_054084351.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011176778.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011186018.1	3	MetaCyc: PWY-7800;MetaCyc: PWY-7799;Reactome: R-HSA-2514859	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_011186889.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_011191289.2	3	Reactome: R-HSA-3214841;Reactome: R-HSA-383280;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_054086910.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_028901203.2	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_011187897.2	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_028901848.2	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_011179938.2	6	KEGG: 04070+3.1.3.66;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516	"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane"
XP_011178993.1	9	KEGG: 00401+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00400+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00960+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00270+2.6.1.5	"Novobiocin biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine catabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Cysteine and methionine metabolism"
XP_011190951.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_054085057.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_028900646.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_011195452.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054087650.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_054085729.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_011181645.2	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_054091489.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_011178491.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011186704.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054086439.1	3	Reactome: R-HSA-427413;Reactome: R-HSA-3214815;Reactome: R-HSA-390522	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones";"Striated Muscle Contraction"
XP_028898293.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_054087876.1	1	KEGG: 00906+1.23.5.1	"Carotenoid biosynthesis"
XP_011194389.1	26	Reactome: R-HSA-5656169;Reactome: R-HSA-8866654;Reactome: R-HSA-5656121;Reactome: R-HSA-69205;Reactome: R-HSA-6804114;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-174417;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-5651801;Reactome: R-HSA-4615885;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-69166;Reactome: R-HSA-1362277;Reactome: R-HSA-5358606;Reactome: R-HSA-110320;Reactome: R-HSA-174437;Reactome: R-HSA-174411;Reactome: R-HSA-174414	"Termination of translesion DNA synthesis";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion synthesis by POLI";"G1/S-Specific Transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Polymerase switching";"Processive synthesis on the lagging strand";"PCNA-Dependent Long Patch Base Excision Repair";"SUMOylation of DNA replication proteins";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Removal of the Flap Intermediate";"Transcription of E2F targets under negative control by DREAM complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate from the C-strand";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the C-strand of the telomere"
XP_011182681.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_054091634.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011193190.2	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_011187662.2	3	Reactome: R-HSA-6807505;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"RNA polymerase II transcribes snRNA genes";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_028899186.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_011190322.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_028900215.2	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_028893835.1	5	Reactome: R-HSA-8849471;Reactome: R-HSA-5218921;Reactome: R-HSA-5658442;Reactome: R-HSA-186763;Reactome: R-HSA-3928662	"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs";"Downstream signal transduction";"EPHB-mediated forward signaling"
XP_011186025.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_011177618.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_054087566.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_011182759.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
XP_011178184.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054082665.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_054091456.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364	"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_011182580.1	12	Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-75893;Reactome: R-HSA-193692;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-5362798;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-982772;Reactome: R-HSA-2644606	"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"TNF signaling";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Release of Hh-Np from the secreting cell";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Growth hormone receptor signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_028894620.2	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_011188158.2	4	KEGG: 00561+2.7.1.30;Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions";"Glycerol degradation I"
XP_011184622.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011190449.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054088029.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_011191702.3	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_011182020.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-9609523;Reactome: R-HSA-1660661	"Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Sphingolipid de novo biosynthesis"
XP_011181713.1	10	Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243	"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Synthesis of PC";"Signal transduction by L1";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_011182587.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_011194269.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_054083490.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011186984.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011189119.2	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_054088757.1	8	Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-6798695;Reactome: R-HSA-8953750	"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Neutrophil degranulation";"Transcriptional Regulation by E2F6"
XP_054084138.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7036;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-6433	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_011186677.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011188856.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_011177191.2	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_028899371.2	17	MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-6679;Reactome: R-HSA-200425;Reactome: R-HSA-2426168;Reactome: R-HSA-196780;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5789;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5743;KEGG: 00254+6.4.1.2;KEGG: 00720+6.4.1.2	"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Candicidin biosynthesis";"Jadomycin biosynthesis";"Carnitine metabolism";"Activation of gene expression by SREBF (SREBP)";"Biotin transport and metabolism";"Glyoxylate assimilation";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propanoate metabolism";"3-hydroxypropanoate cycle";"Aflatoxin biosynthesis";"Carbon fixation pathways in prokaryotes"
XP_054084540.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_011192432.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_054091868.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011179430.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_011196551.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011177010.2	4	KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1	"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism"
XP_011182046.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_054090804.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7036;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6433	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_011189243.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054081111.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_054087244.1	5	MetaCyc: PWY-3841;KEGG: 00670+1.5.1.20;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.20;MetaCyc: PWY-2201	"Folate transformations II (plants)";"One carbon pool by folate";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Folate transformations I"
XP_011188996.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_011196650.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
XP_011182743.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_011182965.2	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_054088952.1	10	KEGG: 00650+2.3.3.10;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-7571;MetaCyc: PWY-6174;KEGG: 00072+2.3.3.10;KEGG: 00900+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-922	"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Ferrichrome A biosynthesis";"Mevalonate pathway II (archaea)";"Synthesis and degradation of ketone bodies";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Mevalonate pathway I"
XP_011185204.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_028895104.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054089826.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_054091306.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_011178898.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054088885.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_054087657.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_011192203.2	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_028897712.2	9	Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_054090591.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_011180063.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_011186511.2	5	Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399;Reactome: R-HSA-5083630	"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3"
XP_054085404.1	11	Reactome: R-HSA-212436;Reactome: R-HSA-2151201;Reactome: R-HSA-383280;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-2426168	"Generic Transcription Pathway";"Transcriptional activation of mitochondrial biogenesis";"Nuclear Receptor transcription pathway";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)"
XP_011194075.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054091613.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_028900842.2	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_054090690.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_054086712.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011185472.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-73856	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination"
XP_054091539.1	19	Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775	"Long-term potentiation";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ion homeostasis"
XP_011188861.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054092041.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_054091190.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_054086750.1	17	Reactome: R-HSA-9014325;Reactome: R-HSA-1169091;Reactome: R-HSA-5357956;Reactome: R-HSA-5689880;Reactome: R-HSA-2871837;Reactome: R-HSA-9645460;Reactome: R-HSA-450321;Reactome: R-HSA-450302;Reactome: R-HSA-202424;Reactome: R-HSA-445989;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-975163;Reactome: R-HSA-937072;Reactome: R-HSA-937042;Reactome: R-HSA-4086398;Reactome: R-HSA-168638	"TICAM1,TRAF6-dependent induction of TAK1 complex";"Activation of NF-kappaB in B cells";"TNFR1-induced NFkappaB signaling pathway";"Ub-specific processing proteases";"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"activated TAK1 mediates p38 MAPK activation";"Downstream TCR signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex";"Ca2+ pathway";"NOD1/2 Signaling Pathway"
XP_054089169.1	6	Reactome: R-HSA-114516;Reactome: R-HSA-76005;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-416993	"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors"
XP_011194930.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_011180971.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_011195442.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_028900751.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_011190730.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011179529.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_054089163.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-114516	"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation"
XP_054082071.1	6	KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920	"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)"
XP_011176714.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054091606.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_011177488.1	11	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-4420097	"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection";"p38MAPK events";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Oxidative Stress Induced Senescence";"VEGFA-VEGFR2 Pathway"
XP_054082285.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_011190941.1	4	Reactome: R-HSA-2586552;Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-982772	"Signaling by Leptin";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling"
XP_028902227.2	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_011192953.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011183901.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_011182878.2	29	MetaCyc: PWY-6342;MetaCyc: PWY-5076;MetaCyc: PWY-5082;MetaCyc: PWY-7118;MetaCyc: PWY-7396;MetaCyc: PWY-7111;KEGG: 00626+1.1.1.1;MetaCyc: PWY-6333;MetaCyc: PWY-5486;MetaCyc: PWY-6802;MetaCyc: PWY-7013;KEGG: 00260+1.1.1.1;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-6871;KEGG: 00592+1.1.1.1;KEGG: 00071+1.1.1.1;MetaCyc: PWY-3162;MetaCyc: PWY-5057;MetaCyc: PWY-6313;KEGG: 00010+1.1.1.1;KEGG: 00980+1.1.1.1;MetaCyc: PWY-6587;KEGG: 00982+1.1.1.1;MetaCyc: PWY-5751;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5078	"Noradrenaline and adrenaline degradation";"L-leucine degradation III";"L-methionine degradation III";"Chitin degradation to ethanol";"Butanol and isobutanol biosynthesis (engineered)";"Pyruvate fermentation to isobutanol (engineered)";"Naphthalene degradation";"Acetaldehyde biosynthesis I";"Pyruvate fermentation to ethanol II";"Salidroside biosynthesis";"(S)-propane-1,2-diol degradation";"Glycine, serine and threonine metabolism";"Chloroalkane and chloroalkene degradation";"Pyruvate fermentation to ethanol I";"Tyrosine metabolism";"L-phenylalanine degradation III";"3-methylbutanol biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"L-tryptophan degradation V (side chain pathway)";"L-valine degradation II";"Serotonin degradation";"Glycolysis / Gluconeogenesis";"Metabolism of xenobiotics by cytochrome P450";"Pyruvate fermentation to ethanol III";"Drug metabolism - cytochrome P450";"Phenylethanol biosynthesis";"Retinol metabolism";"L-isoleucine degradation II"
XP_011181595.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_028896372.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_011195914.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_028900473.2	20	MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-6920;MetaCyc: PWY-7606;Reactome: R-HSA-9033241;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-7858;MetaCyc: PWY-6837;KEGG: 00640+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7854	"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoate metabolism";"beta-Alanine metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)"
XP_011187832.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_011184045.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_028895088.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054091030.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_054083345.1	6	Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_054086264.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_011192209.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011185774.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_011192405.1	4	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
XP_011187304.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054091446.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_028894473.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_054087400.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054084098.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-9037629	"Voltage gated Potassium channels";"Lewis blood group biosynthesis"
XP_054082292.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_054081130.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011188274.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_011190169.2	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_011184990.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_011186352.2	9	Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome"
XP_011181706.1	7	Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-3371453;Reactome: R-HSA-381070;Reactome: R-HSA-381042;Reactome: R-HSA-381183;Reactome: R-HSA-114608	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Platelet degranulation"
XP_011182529.1	26	Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-389977;Reactome: R-HSA-9648025;Reactome: R-HSA-389960;Reactome: R-HSA-5626467	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Gap junction assembly";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Post-chaperonin tubulin folding pathway";"EML4 and NUDC in mitotic spindle formation";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases activate IQGAPs"
XP_011177378.2	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_054089792.1	14	Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-68877;Reactome: R-HSA-2565942;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-380270;Reactome: R-HSA-2467813;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Mitotic Prometaphase";"Regulation of PLK1 Activity at G2/M Transition";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Recruitment of mitotic centrosome proteins and complexes";"Separation of Sister Chromatids";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_054088087.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054090390.1	6	Reactome: R-HSA-114516;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-5099900	"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4"
XP_054092171.1	22	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5358752;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins"
XP_011196532.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_011196174.1	5	KEGG: 00770+2.7.8.7;MetaCyc: PWY-6012;MetaCyc: PWY-6012-1;MetaCyc: PWY-6289;Reactome: R-HSA-199220	"Pantothenate and CoA biosynthesis";"Acyl carrier protein metabolism";"Acyl carrier protein activation";"Petrobactin biosynthesis";"Vitamin B5 (pantothenate) metabolism"
XP_011196647.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497	"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_054088280.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011181765.2	2	Reactome: R-HSA-73621;Reactome: R-HSA-500753	"Pyrimidine catabolism";"Pyrimidine biosynthesis"
XP_011194567.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054088726.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_011195799.2	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_011197107.2	9	KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52	"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Other glycan degradation";"Various types of N-glycan biosynthesis"
XP_011179878.2	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_011183955.2	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_011189550.1	10	Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-5628897;Reactome: R-HSA-611105;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-3299685;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-2151201	"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"TP53 Regulates Metabolic Genes";"Respiratory electron transport";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Detoxification of Reactive Oxygen Species";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis"
XP_054088546.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054088064.1	8	KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-5673001	"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade"
XP_011178110.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_011187118.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012	"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_011188321.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_011191613.1	14	MetaCyc: PWY-7254;Reactome: R-HSA-611105;MetaCyc: PWY-5690;MetaCyc: PWY-561;KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-4302;MetaCyc: PWY-3781;Reactome: R-HSA-71403;MetaCyc: PWY-7279;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6728	"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Butanoate metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration I (cytochrome c)";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Methylaspartate cycle"
XP_028894475.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_011196777.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_028896129.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011190789.2	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_011191011.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_011179638.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_028895460.1	22	Reactome: R-HSA-389513;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"CTLA4 inhibitory signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"RAF activation";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_011186750.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_054091116.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_028898458.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_011181185.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_054091471.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364	"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_011177267.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011194371.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_028900065.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_011178012.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_054086218.1	5	Reactome: R-HSA-8964539;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;MetaCyc: PWY-3341	"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)"
XP_054082283.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_011179915.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_054083171.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_054087576.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-7782;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-5981;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51	"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism"
XP_054089086.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68949	"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin"
XP_054081998.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_011187962.1	17	Reactome: R-HSA-5693616;Reactome: R-HSA-1834949;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-2559586;Reactome: R-HSA-5685939;Reactome: R-HSA-5693568	"Presynaptic phase of homologous DNA pairing and strand exchange";"Cytosolic sensors of pathogen-associated DNA";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"DNA Damage/Telomere Stress Induced Senescence";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_054083266.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_054089165.1	6	Reactome: R-HSA-5099900;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-114516	"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation"
XP_028898710.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_054081949.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_054089922.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054087493.1	3	Reactome: R-HSA-881907;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Gastrin-CREB signalling pathway via PKC and MAPK";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_054090303.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054082020.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_011189603.2	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_011178735.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054090498.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_028895573.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_011193798.1	5	Reactome: R-HSA-168638;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-171007	"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"DSCAM interactions";"p38MAPK events"
XP_011184043.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_011193749.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_011187340.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_011192895.2	4	Reactome: R-HSA-6799198;Reactome: R-HSA-975138;Reactome: R-HSA-975871;Reactome: R-HSA-166058	"Complex I biogenesis";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane"
XP_028898957.1	8	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-182218;Reactome: R-HSA-9636467;Reactome: R-HSA-917977;Reactome: R-HSA-167590;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Amino acids regulate mTORC1";"Nef Mediated CD8 Down-regulation";"Blockage of phagosome acidification";"Transferrin endocytosis and recycling";"Nef Mediated CD4 Down-regulation";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_011182880.1	29	MetaCyc: PWY-6802;MetaCyc: PWY-7013;KEGG: 00260+1.1.1.1;MetaCyc: PWY-5486;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00626+1.1.1.1;MetaCyc: PWY-6333;MetaCyc: PWY-7118;MetaCyc: PWY-7396;MetaCyc: PWY-7111;MetaCyc: PWY-6342;MetaCyc: PWY-5082;MetaCyc: PWY-5076;KEGG: 00982+1.1.1.1;KEGG: 00980+1.1.1.1;MetaCyc: PWY-6587;MetaCyc: PWY-5078;MetaCyc: PWY-5751;KEGG: 00830+1.1.1.1;KEGG: 00071+1.1.1.1;KEGG: 00592+1.1.1.1;MetaCyc: PWY-6313;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5057;MetaCyc: PWY-3162;MetaCyc: PWY-6871;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5079	"Salidroside biosynthesis";"(S)-propane-1,2-diol degradation";"Glycine, serine and threonine metabolism";"Pyruvate fermentation to ethanol II";"Chloroalkane and chloroalkene degradation";"Pyruvate fermentation to ethanol I";"Naphthalene degradation";"Acetaldehyde biosynthesis I";"Chitin degradation to ethanol";"Butanol and isobutanol biosynthesis (engineered)";"Pyruvate fermentation to isobutanol (engineered)";"Noradrenaline and adrenaline degradation";"L-methionine degradation III";"L-leucine degradation III";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Pyruvate fermentation to ethanol III";"L-isoleucine degradation II";"Phenylethanol biosynthesis";"Retinol metabolism";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Serotonin degradation";"Glycolysis / Gluconeogenesis";"L-valine degradation II";"L-tryptophan degradation V (side chain pathway)";"3-methylbutanol biosynthesis (engineered)";"Tyrosine metabolism";"L-phenylalanine degradation III"
XP_011195513.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011189128.2	33	Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-141444	"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"tRNA processing in the nucleus";"snRNP Assembly";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_011186561.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_054088996.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_054083343.1	6	Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-8874081;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216	"Non-integrin membrane-ECM interactions";"Collagen degradation";"MET activates PTK2 signaling";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization"
XP_011187767.1	8	Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER"
XP_054088889.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_054082529.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054081601.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_011179071.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_011194671.1	8	KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171	"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Starch and sucrose metabolism";"Glycolysis"
XP_011180630.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_011195964.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_011193564.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Notch-HLH transcription pathway"
XP_028896295.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_011188520.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_011193227.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_054082798.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_054089756.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_054089651.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_028901544.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation"
XP_028894510.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_011179338.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation"
XP_011184049.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054088827.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_011187357.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_054084850.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_011193020.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_054085555.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_011196926.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011188064.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_028897310.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_054081500.1	10	Reactome: R-HSA-2151209;Reactome: R-HSA-200425;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354	"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Lipophagy"
XP_011188280.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054084812.1	8	Reactome: R-HSA-5683826;MetaCyc: PWY-6611;MetaCyc: PWY-6609;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179	"Surfactant metabolism";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Neutrophil degranulation";"Purine metabolism";"Purine deoxyribonucleosides degradation I"
XP_011191420.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054089512.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_028899992.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_054091979.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_011189785.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_011187248.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054083041.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054083232.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_028897530.1	52	Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-5601884;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-72163;Reactome: R-HSA-5578749;Reactome: R-HSA-76071;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-72203;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-76066;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-203927;Reactome: R-HSA-73980;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-5250924;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-76061;Reactome: R-HSA-73776;Reactome: R-HSA-1834949	"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"mRNA Splicing - Major Pathway";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Processing of Capped Intron-Containing Pre-mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"mRNA Capping";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Transcription Termination";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Promoter Escape";"Cytosolic sensors of pathogen-associated DNA"
XP_011195795.2	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_028895881.2	3	KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662	"Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_054084905.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5461	"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation"
XP_054090941.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_028899346.2	1	Reactome: R-HSA-3000178	"ECM proteoglycans"
XP_054082176.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-937039;Reactome: R-HSA-975144	"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_028900153.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Clathrin-mediated endocytosis"
XP_054091103.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054089666.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_011186080.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_054086846.1	16	Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-9018519;Reactome: R-HSA-5693568;Reactome: R-HSA-201722;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565	"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"Estrogen-dependent gene expression";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Formation of the beta-catenin:TCF transactivating complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_054087608.1	16	Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-141430	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex"
XP_054081112.1	6	Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_028898510.2	2	Reactome: R-HSA-6793080;Reactome: R-HSA-2151201	"rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis"
XP_011180752.2	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_011188049.2	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_054087034.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054084537.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_011196013.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011191062.2	6	Reactome: R-HSA-8963889;Reactome: R-HSA-8957275;Reactome: R-HSA-8874211;Reactome: R-HSA-381426;Reactome: R-HSA-381033;Reactome: R-HSA-1655829	"Assembly of active LPL and LIPC lipase complexes";"Post-translational protein phosphorylation";"CREB3 factors activate genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_011182188.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_011193291.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-192823	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation"
XP_011195858.1	4	KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_054088951.1	10	MetaCyc: PWY-922;KEGG: 00900+2.3.3.10;Reactome: R-HSA-1989781;KEGG: 00072+2.3.3.10;MetaCyc: PWY-6174;MetaCyc: PWY-7391;MetaCyc: PWY-7571;MetaCyc: PWY-7524;KEGG: 00650+2.3.3.10;KEGG: 00280+2.3.3.10	"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Synthesis and degradation of ketone bodies";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Ferrichrome A biosynthesis";"Mevalonate pathway III (archaea)";"Butanoate metabolism";"Valine, leucine and isoleucine degradation"
XP_011176529.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_011186332.2	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_011178663.2	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_054088891.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054091177.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054091644.1	16	Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-426496	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"Post-transcriptional silencing by small RNAs"
XP_011191701.3	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_028899640.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011184621.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_028899495.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_054086449.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_011180957.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_028893644.1	22	Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5358747	"RAF activation";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated"
XP_011189846.2	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_011192431.2	4	Reactome: R-HSA-947581;Reactome: R-HSA-1362409;MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7	"Molybdenum cofactor biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism"
XP_054090144.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054090585.1	7	Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation"
XP_011177297.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646	"Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification"
XP_054090677.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_011194007.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_054081968.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_011179607.1	7	Reactome: R-HSA-373753;Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"Nephrin family interactions";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_054091257.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_011190791.2	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_011196330.1	10	Reactome: R-HSA-1855191;MetaCyc: PWY-6361;MetaCyc: PWY-6372;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-6369;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6362;Reactome: R-HSA-1855167	"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of pyrophosphates in the cytosol"
XP_054090218.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_054084480.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_054089396.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_054087424.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_011186298.2	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_054083758.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation"
XP_028898867.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_011196884.2	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_054087213.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_011183252.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_011188862.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054092042.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_011194742.1	24	Reactome: R-HSA-4420097;Reactome: R-HSA-163358;KEGG: 04150+2.7.11.11;Reactome: R-HSA-422356;Reactome: R-HSA-111931;Reactome: R-HSA-5621575;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-5610780;Reactome: R-HSA-8853659;Reactome: R-HSA-180024;Reactome: R-HSA-5610783;Reactome: R-HSA-5610787;Reactome: R-HSA-5610785;Reactome: R-HSA-163615;Reactome: R-HSA-392517;Reactome: R-HSA-381676;Reactome: R-HSA-5687128;Reactome: R-HSA-163560;Reactome: R-HSA-8963896;Reactome: R-HSA-983231;Reactome: R-HSA-9634600;Reactome: R-HSA-164378;Reactome: R-HSA-9010642	"VEGFA-VEGFR2 Pathway";"PKA-mediated phosphorylation of key metabolic factors";"mTOR signaling pathway";"Regulation of insulin secretion";"PKA-mediated phosphorylation of CREB";"CD209 (DC-SIGN) signaling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"Degradation of GLI1 by the proteasome";"RET signaling";"DARPP-32 events";"Degradation of GLI2 by the proteasome";"Hedgehog 'off' state";"GLI3 is processed to GLI3R by the proteasome";"PKA activation";"Rap1 signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"MAPK6/MAPK4 signaling";"Triglyceride catabolism";"HDL assembly";"Factors involved in megakaryocyte development and platelet production";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"PKA activation in glucagon signalling";"ROBO receptors bind AKAP5"
XP_011189487.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_011177724.2	14	MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602	"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_011188173.2	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_054091012.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_028900454.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_011193768.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_054084317.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_054088453.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_011190425.2	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_011178471.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_011180777.1	11	Reactome: R-HSA-525793;Reactome: R-HSA-8940973;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-8939236;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565	"Myogenesis";"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_011192088.1	3	MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493	"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2"
XP_011178116.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_011194200.1	7	MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00010+3.1.3.11;KEGG: 00680+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00051+3.1.3.11	"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism"
XP_028900000.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Aggrephagy";"Mitotic Prometaphase"
XP_028896463.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011194282.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054082594.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_011192819.1	3	MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403	"5-oxo-L-proline metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_054081270.1	13	KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;Reactome: R-HSA-4341670;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;Reactome: R-HSA-2206308;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23	"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Defective NEU1 causes sialidosis";"Sphingolipid metabolism";"Galactose metabolism";"Sialic acid metabolism";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"MPS IV - Morquio syndrome B";"HS-GAG degradation";"Other glycan degradation"
XP_054083088.1	7	Reactome: R-HSA-9020265;Reactome: R-HSA-9018681;Reactome: R-HSA-6798695;Reactome: R-HSA-9023661;Reactome: R-HSA-2142691;Reactome: R-HSA-9018676;Reactome: R-HSA-9018896	"Biosynthesis of aspirin-triggered D-series resolvins";"Biosynthesis of protectins";"Neutrophil degranulation";"Biosynthesis of E-series 18(R)-resolvins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of D-series resolvins";"Biosynthesis of E-series 18(S)-resolvins"
XP_011190080.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_011178220.2	4	Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695	"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"HS-GAG degradation";"Neutrophil degranulation"
XP_028896371.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054090988.1	15	Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128	"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"Ca2+ pathway";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling"
XP_028893586.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054083819.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_011184684.2	5	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-9630222;Reactome: R-HSA-9630221;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate binding";"Defective NTHL1 substrate processing";"Displacement of DNA glycosylase by APEX1"
XP_054088459.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_011189984.1	23	Reactome: R-HSA-202040;Reactome: R-HSA-418217;Reactome: R-HSA-6814122;Reactome: R-HSA-381676;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-400042;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-9009391;Reactome: R-HSA-428930;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-8964315;Reactome: R-HSA-456926;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-432040;Reactome: R-HSA-392851	"G-protein activation";"G beta:gamma signalling through PLC beta";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"Extra-nuclear estrogen signaling";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"G beta:gamma signalling through BTK";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor"
XP_054086603.1	5	KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I"
XP_054086536.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_011191578.3	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054089418.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_011185938.1	7	KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379716;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.15;Reactome: R-HSA-2408522	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_011190942.1	4	Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-2586552	"Growth hormone receptor signaling";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin"
XP_011191208.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-202040	"PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation"
XP_054091559.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_011178938.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011178103.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_054090820.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054082072.1	6	KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11	"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis"
XP_011184772.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054090074.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054083806.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_054091780.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_028900752.1	19	Reactome: R-HSA-8964038;Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-8866423;Reactome: R-HSA-202733;Reactome: R-HSA-8964041;Reactome: R-HSA-8957275;Reactome: R-HSA-3000497;Reactome: R-HSA-8856825;Reactome: R-HSA-5686938;Reactome: R-HSA-975634;Reactome: R-HSA-8963888;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-3000471;Reactome: R-HSA-8964046;Reactome: R-HSA-3000480;Reactome: R-HSA-3000484;Reactome: R-HSA-8856828	"LDL clearance";"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL assembly";"Cell surface interactions at the vascular wall";"LDL remodeling";"Post-translational protein phosphorylation";"Scavenging by Class H Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Retinoid metabolism and transport";"Chylomicron assembly";"Chylomicron remodeling";"Platelet sensitization by LDL";"Scavenging by Class B Receptors";"VLDL clearance";"Scavenging by Class A Receptors";"Scavenging by Class F Receptors";"Clathrin-mediated endocytosis"
XP_011190287.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_054087927.1	10	Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73779	"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_011183126.2	3	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions"
XP_011191555.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054088622.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_011196703.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72695	"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_011176675.2	8	MetaCyc: PWY-7400;MetaCyc: PWY-5;KEGG: 00220+4.3.2.1;Reactome: R-HSA-70635;KEGG: 00250+4.3.2.1;MetaCyc: PWY-4983;MetaCyc: PWY-5154;MetaCyc: PWY-4984	"L-arginine biosynthesis IV (archaebacteria)";"Canavanine biosynthesis";"Arginine biosynthesis";"Urea cycle";"Alanine, aspartate and glutamate metabolism";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle"
XP_028897115.2	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_011176906.2	9	Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948	"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Platelet degranulation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants"
XP_011178814.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_011195719.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_011178615.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011177728.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7601	"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_011193142.1	8	MetaCyc: PWY-5668;KEGG: 04660+3.1.3.16;MetaCyc: PWY-7817;KEGG: 05235+3.1.3.16;KEGG: 00564+3.1.3.27;MetaCyc: PWY-5269;KEGG: 04658+3.1.3.16;Reactome: R-HSA-1483148	"Cardiolipin biosynthesis I";"T cell receptor signaling pathway";"Type I lipoteichoic acid biosynthesis (S. aureus)";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II";"Th1 and Th2 cell differentiation";"Synthesis of PG"
XP_011196531.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_011179412.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_011193543.2	31	MetaCyc: PWY-8047;MetaCyc: PWY-7663;Reactome: R-HSA-75105;MetaCyc: PWY-7746;MetaCyc: PWY-5973;Reactome: R-HSA-9029558;MetaCyc: PWY-5366;MetaCyc: PWY-5142;MetaCyc: PWY-5994;Reactome: R-HSA-163765;MetaCyc: PWY-6282;MetaCyc: PWY-8012;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-8049;MetaCyc: PWY-5971;MetaCyc: PWY-7664;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-199220;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-4381;MetaCyc: PWY-5147;MetaCyc: PWY-5367;Reactome: R-HSA-2426168;MetaCyc: PWY-7388;MetaCyc: PWY-6113;MetaCyc: PWY-7858;MetaCyc: PWY-7723;MetaCyc: PWY-5966-1;MetaCyc: PWY-5989;MetaCyc: PWYG-321	"Bryostatin biosynthesis";"Gondoate biosynthesis (anaerobic)";"Fatty acyl-CoA biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Cis-vaccenate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mupirocin biosynthesis";"Fatty acid biosynthesis";"Pederin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Biotin metabolism";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis I (plants)";"Petroselinate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Superpathway of mycolate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Bacterial bioluminescence";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";""
XP_054085420.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-170670	"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Purine metabolism";"G alpha (z) signalling events";"G alpha (s) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway"
XP_054086443.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_028896079.1	6	MetaCyc: PWY-7426;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143	"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis"
XP_054087194.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011176833.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_011186351.2	9	Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation"
XP_054082291.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_028896194.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011181136.2	5	Reactome: R-HSA-205043;Reactome: R-HSA-209543;Reactome: R-HSA-5205685;Reactome: R-HSA-9020702;Reactome: R-HSA-209560	"NRIF signals cell death from the nucleus";"p75NTR recruits signalling complexes";"Pink/Parkin Mediated Mitophagy";"Interleukin-1 signaling";"NF-kB is activated and signals survival"
XP_054084239.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_028900135.1	83	Reactome: R-HSA-8875360;Reactome: R-HSA-9634285;Reactome: R-HSA-179812;Reactome: R-HSA-354194;Reactome: R-HSA-8853338;Reactome: R-HSA-2424491;Reactome: R-HSA-74751;Reactome: R-HSA-5654688;Reactome: R-HSA-8875656;Reactome: R-HSA-5654712;Reactome: R-HSA-9664565;Reactome: R-HSA-5637810;Reactome: R-HSA-2219530;Reactome: R-HSA-180336;Reactome: R-HSA-5654726;Reactome: R-HSA-182971;Reactome: R-HSA-1963642;Reactome: R-HSA-5654700;Reactome: R-HSA-186763;Reactome: R-HSA-1236382;Reactome: R-HSA-5655302;Reactome: R-HSA-6811558;Reactome: R-HSA-5654727;Reactome: R-HSA-6807004;Reactome: R-HSA-5654689;Reactome: R-HSA-8851805;Reactome: R-HSA-8851907;Reactome: R-HSA-2871809;Reactome: R-HSA-1250196;Reactome: R-HSA-1433557;Reactome: R-HSA-167044;Reactome: R-HSA-8853659;Reactome: R-HSA-388841;Reactome: R-HSA-8856828;Reactome: R-HSA-74749;Reactome: R-HSA-1257604;Reactome: R-HSA-5654732;Reactome: R-HSA-2871796;Reactome: R-HSA-2029482;Reactome: R-HSA-2428933;Reactome: R-HSA-2730905;Reactome: R-HSA-983695;Reactome: R-HSA-8856825;Reactome: R-HSA-375165;Reactome: R-HSA-210993;Reactome: R-HSA-9026519;Reactome: R-HSA-180292;Reactome: R-HSA-9027284;Reactome: R-HSA-112412;Reactome: R-HSA-5654733;Reactome: R-HSA-1295596;Reactome: R-HSA-8875555;Reactome: R-HSA-1963640;Reactome: R-HSA-9034864;Reactome: R-HSA-5655291;Reactome: R-HSA-5673001;Reactome: R-HSA-5663213;Reactome: R-HSA-9645135;Reactome: R-HSA-5654710;Reactome: R-HSA-5655253;Reactome: R-HSA-512988;Reactome: R-HSA-5654704;Reactome: R-HSA-5654706;Reactome: R-HSA-109704;Reactome: R-HSA-9607240;Reactome: R-HSA-389359;Reactome: R-HSA-1250347;Reactome: R-HSA-912631;Reactome: R-HSA-8853334;Reactome: R-HSA-5654720;Reactome: R-HSA-9028335;Reactome: R-HSA-391160;Reactome: R-HSA-8865999;Reactome: R-HSA-1433559;Reactome: R-HSA-5654719;Reactome: R-HSA-2179392;Reactome: R-HSA-1839117;Reactome: R-HSA-5654699;Reactome: R-HSA-912526;Reactome: R-HSA-5654693;Reactome: R-HSA-9028731;Reactome: R-HSA-5654695;Reactome: R-HSA-8983432	"InlB-mediated entry of Listeria monocytogenes into host cell";"Constitutive Signaling by Overexpressed ERBB2";"GRB2 events in EGFR signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Signaling by FGFR3 point mutants in cancer";"DAP12 signaling";"Insulin receptor signalling cascade";"SHC-mediated cascade:FGFR1";"MET receptor recycling";"FRS-mediated FGFR4 signaling";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in EGFR signaling";"Negative regulation of FGFR1 signaling";"EGFR downregulation";"PI3K events in ERBB2 signaling";"FRS-mediated FGFR2 signaling";"Downstream signal transduction";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by FGFR1 in disease";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of FGFR2 signaling";"Negative regulation of MET activity";"PI-3K cascade:FGFR1";"MET activates RAS signaling";"MET activates PI3K/AKT signaling";"FCERI mediated Ca+2 mobilization";"SHC1 events in ERBB2 signaling";"Signaling by SCF-KIT";"Signalling to RAS";"RET signaling";"Costimulation by the CD28 family";"Clathrin-mediated endocytosis";"Signal attenuation";"PIP3 activates AKT signaling";"Negative regulation of FGFR3 signaling";"FCERI mediated MAPK activation";"Regulation of actin dynamics for phagocytic cup formation";"SHC-related events triggered by IGF1R";"Role of LAT2/NTAL/LAB on calcium mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Cargo recognition for clathrin-mediated endocytosis";"NCAM signaling for neurite out-growth";"Tie2 Signaling";"Activated NTRK2 signals through RAS";"GAB1 signalosome";"Erythropoietin activates RAS";"SOS-mediated signalling";"Negative regulation of FGFR4 signaling";"Spry regulation of FGF signaling";"MET activates RAP1 and RAC1";"GRB2 events in ERBB2 signaling";"Activated NTRK3 signals through RAS";"Signaling by FGFR4 in disease";"RAF/MAP kinase cascade";"RHO GTPases Activate WASPs and WAVEs";"STAT5 Activation";"PI-3K cascade:FGFR3";"Signaling by FGFR2 in disease";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"SHC-mediated cascade:FGFR3";"FRS-mediated FGFR3 signaling";"PI3K Cascade";"FLT3 Signaling";"CD28 dependent Vav1 pathway";"SHC1 events in ERBB4 signaling";"Regulation of signaling by CBL";"Signaling by FGFR3 fusions in cancer";"PI-3K cascade:FGFR4";"Activated NTRK2 signals through PI3K";"Signal regulatory protein family interactions";"MET activates PTPN11";"Regulation of KIT signaling";"SHC-mediated cascade:FGFR4";"EGFR Transactivation by Gastrin";"Signaling by cytosolic FGFR1 fusion mutants";"SHC-mediated cascade:FGFR2";"Interleukin receptor SHC signaling";"FRS-mediated FGFR1 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"PI-3K cascade:FGFR2";"Interleukin-15 signaling"
YP_004891165.1	7	Reactome: R-HSA-6799198;KEGG: 00190+7.1.1.2;MetaCyc: PWY-5083;MetaCyc: PWY-4302;MetaCyc: PWY-3781;MetaCyc: PWY-6692;Reactome: R-HSA-611105	"Complex I biogenesis";"Oxidative phosphorylation";"NAD/NADH phosphorylation and dephosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Respiratory electron transport"
XP_054089791.1	14	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-380270;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-380259;Reactome: R-HSA-6811436	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Recruitment of mitotic centrosome proteins and complexes";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic"
XP_054086115.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_054081565.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_011177659.2	7	Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_054085446.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_011185814.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_011177497.2	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_011183477.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011193944.1	4	Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054088862.1	11	Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-3000170;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-202733;Reactome: R-HSA-975634	"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"Syndecan interactions";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport"
XP_011196705.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72702	"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition"
XP_011190652.2	17	Reactome: R-HSA-200425;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;KEGG: 00720+6.4.1.2;KEGG: 00254+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-5789;Reactome: R-HSA-3371599;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-196780	"Carnitine metabolism";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carbon fixation pathways in prokaryotes";"Aflatoxin biosynthesis";"Pyruvate metabolism";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Propanoate metabolism";"Glyoxylate assimilation";"Biotin transport and metabolism"
XP_011183939.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011185190.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_011178829.2	6	Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_011195724.2	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_054087992.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_028894407.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_054091472.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling"
XP_054086445.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_011187517.1	10	Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation"
XP_054081267.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_011177301.1	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_011180876.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_028901147.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011176525.2	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_011188322.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_028898560.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_011192980.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_011194626.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011180505.2	6	MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;MetaCyc: PWY-622;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_011187896.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300	"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"G0 and Early G1";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_054089487.1	8	MetaCyc: PWY-7179;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-6611;Reactome: R-HSA-5683826	"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Purine metabolism";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Surfactant metabolism"
XP_011184317.1	3	Reactome: R-HSA-189085;Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"Digestion of dietary carbohydrate";"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054084474.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_028901378.1	12	Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-72662;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-166208	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"ISG15 antiviral mechanism";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling"
XP_054086113.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_011179723.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_011193450.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_011179142.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054082607.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054082188.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011193718.2	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_011190331.2	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_011182040.2	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_028899187.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_011187776.2	13	Reactome: R-HSA-2424491;Reactome: R-HSA-2871809;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2871796;MetaCyc: PWY-6367;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-9027277;MetaCyc: PWY-6351;Reactome: R-HSA-202433;MetaCyc: PWY-8052;Reactome: R-HSA-2029485	"DAP12 signaling";"FCERI mediated Ca+2 mobilization";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"FCERI mediated MAPK activation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Erythropoietin activates Phospholipase C gamma (PLCG)";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Generation of second messenger molecules";"2-arachidonoylglycerol biosynthesis";"Role of phospholipids in phagocytosis"
XP_011181112.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation"
XP_011190225.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_054087985.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_011183978.2	2	Reactome: R-HSA-5627123;Reactome: R-HSA-8856828	"RHO GTPases activate PAKs";"Clathrin-mediated endocytosis"
XP_054089921.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_011178578.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011190144.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_011187961.1	4	Reactome: R-HSA-1655829;Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-8963889	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes"
XP_054088697.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_011182142.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054084688.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011177009.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_054090871.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011183410.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_011186303.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_028896346.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_028901678.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054091555.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_028897390.2	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_011197138.2	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_011180174.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011181633.2	11	Reactome: R-HSA-111459;Reactome: R-HSA-1268020;Reactome: R-HSA-111457;Reactome: R-HSA-611105;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-2151201;Reactome: R-HSA-9627069;Reactome: R-HSA-3299685	"Activation of caspases through apoptosome-mediated cleavage";"Mitochondrial protein import";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Transcriptional activation of mitochondrial biogenesis";"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species"
XP_011192534.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_011180647.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_011192625.2	5	Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-6784531	"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus"
XP_011195130.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054088455.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054086390.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_011181565.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011189712.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_011185446.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_011195686.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011182354.2	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_054086294.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_028895694.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054089652.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_054083815.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_011181964.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_028899890.2	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_054086119.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_054081569.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_028894044.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_054089984.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054084068.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_028896741.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_011185619.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054090527.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_011190377.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_011187143.2	3	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_011190988.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054084235.1	6	MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7433	"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation"
XP_054083980.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_011180407.1	56	Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761	"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_054090360.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
YP_004891169.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_011185665.2	4	MetaCyc: PWY-6030;Reactome: R-HSA-209931;KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4	"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Folate biosynthesis"
XP_011183409.3	8	KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533;MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;KEGG: 00983+2.5.1.18	"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Drug metabolism - other enzymes"
XP_011185823.2	26	Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-5617472;Reactome: R-HSA-8866907;Reactome: R-HSA-1989781;Reactome: R-HSA-5621575;Reactome: R-HSA-210744;Reactome: R-HSA-9617629;Reactome: R-HSA-201722;Reactome: R-HSA-933541;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-3214847;Reactome: R-HSA-1368082;Reactome: R-HSA-3899300;Reactome: R-HSA-2644606;Reactome: R-HSA-9614657;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-2894862;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-3134973	"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of the TFAP2 (AP-2) family of transcription factors";"PPARA activates gene expression";"CD209 (DC-SIGN) signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of FOXO transcriptional activity by acetylation";"Formation of the beta-catenin:TCF transactivating complex";"TRAF6 mediated IRF7 activation";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"HATs acetylate histones";"RORA activates gene expression";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"
XP_054087588.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_054081879.1	8	Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-8953750;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Transcriptional Regulation by E2F6";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_028893682.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_011184861.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054081442.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011187371.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054089429.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_028901513.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-7782	"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Plasmalogen biosynthesis"
XP_011178665.2	20	MetaCyc: PWY-7854;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7291;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-7606;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-7574;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Propanoate metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"
XP_011185606.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852	"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy"
XP_054090942.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054083231.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_011191559.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_011178619.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054083042.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_028893843.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-429958	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_054088094.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-163359	"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"G alpha (z) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation"
XP_011188486.1	15	Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-2559586;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571	"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)"
XP_054089224.1	83	Reactome: R-HSA-2428933;Reactome: R-HSA-2029482;Reactome: R-HSA-8856825;Reactome: R-HSA-983695;Reactome: R-HSA-2730905;Reactome: R-HSA-8853659;Reactome: R-HSA-167044;Reactome: R-HSA-1433557;Reactome: R-HSA-2871809;Reactome: R-HSA-1250196;Reactome: R-HSA-8851907;Reactome: R-HSA-1257604;Reactome: R-HSA-5654732;Reactome: R-HSA-2871796;Reactome: R-HSA-74749;Reactome: R-HSA-8856828;Reactome: R-HSA-388841;Reactome: R-HSA-1963642;Reactome: R-HSA-182971;Reactome: R-HSA-5654726;Reactome: R-HSA-180336;Reactome: R-HSA-8851805;Reactome: R-HSA-5654689;Reactome: R-HSA-6807004;Reactome: R-HSA-6811558;Reactome: R-HSA-5655302;Reactome: R-HSA-5654727;Reactome: R-HSA-1236382;Reactome: R-HSA-186763;Reactome: R-HSA-5654700;Reactome: R-HSA-74751;Reactome: R-HSA-2424491;Reactome: R-HSA-5654688;Reactome: R-HSA-8853338;Reactome: R-HSA-354194;Reactome: R-HSA-179812;Reactome: R-HSA-8875360;Reactome: R-HSA-9634285;Reactome: R-HSA-2219530;Reactome: R-HSA-5637810;Reactome: R-HSA-9664565;Reactome: R-HSA-5654712;Reactome: R-HSA-8875656;Reactome: R-HSA-5654699;Reactome: R-HSA-1839117;Reactome: R-HSA-2179392;Reactome: R-HSA-8983432;Reactome: R-HSA-5654695;Reactome: R-HSA-9028731;Reactome: R-HSA-5654693;Reactome: R-HSA-912526;Reactome: R-HSA-8853334;Reactome: R-HSA-1250347;Reactome: R-HSA-912631;Reactome: R-HSA-9607240;Reactome: R-HSA-389359;Reactome: R-HSA-109704;Reactome: R-HSA-5654706;Reactome: R-HSA-5654719;Reactome: R-HSA-1433559;Reactome: R-HSA-391160;Reactome: R-HSA-8865999;Reactome: R-HSA-9028335;Reactome: R-HSA-5654720;Reactome: R-HSA-5654710;Reactome: R-HSA-9645135;Reactome: R-HSA-5663213;Reactome: R-HSA-5673001;Reactome: R-HSA-512988;Reactome: R-HSA-5654704;Reactome: R-HSA-5655253;Reactome: R-HSA-1295596;Reactome: R-HSA-5654733;Reactome: R-HSA-112412;Reactome: R-HSA-180292;Reactome: R-HSA-9027284;Reactome: R-HSA-375165;Reactome: R-HSA-9026519;Reactome: R-HSA-210993;Reactome: R-HSA-5655291;Reactome: R-HSA-9034864;Reactome: R-HSA-1963640;Reactome: R-HSA-8875555	"SHC-related events triggered by IGF1R";"Regulation of actin dynamics for phagocytic cup formation";"Cargo recognition for clathrin-mediated endocytosis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Role of LAT2/NTAL/LAB on calcium mobilization";"RET signaling";"Signalling to RAS";"Signaling by SCF-KIT";"FCERI mediated Ca+2 mobilization";"SHC1 events in ERBB2 signaling";"MET activates PI3K/AKT signaling";"PIP3 activates AKT signaling";"Negative regulation of FGFR3 signaling";"FCERI mediated MAPK activation";"Signal attenuation";"Clathrin-mediated endocytosis";"Costimulation by the CD28 family";"PI3K events in ERBB2 signaling";"EGFR downregulation";"Negative regulation of FGFR1 signaling";"SHC1 events in EGFR signaling";"MET activates RAS signaling";"PI-3K cascade:FGFR1";"Negative regulation of MET activity";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by FGFR1 in disease";"Negative regulation of FGFR2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Downstream signal transduction";"FRS-mediated FGFR2 signaling";"Insulin receptor signalling cascade";"DAP12 signaling";"SHC-mediated cascade:FGFR1";"Signaling by FGFR3 point mutants in cancer";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"GRB2 events in EGFR signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by Aberrant PI3K in Cancer";"Constitutive Signaling by EGFRvIII";"Signaling by ERBB2 KD Mutants";"FRS-mediated FGFR4 signaling";"MET receptor recycling";"SHC-mediated cascade:FGFR2";"Signaling by cytosolic FGFR1 fusion mutants";"EGFR Transactivation by Gastrin";"Interleukin-15 signaling";"PI-3K cascade:FGFR2";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR1 signaling";"Interleukin receptor SHC signaling";"Signaling by FGFR3 fusions in cancer";"SHC1 events in ERBB4 signaling";"Regulation of signaling by CBL";"FLT3 Signaling";"CD28 dependent Vav1 pathway";"PI3K Cascade";"FRS-mediated FGFR3 signaling";"SHC-mediated cascade:FGFR4";"Regulation of KIT signaling";"Signal regulatory protein family interactions";"MET activates PTPN11";"Activated NTRK2 signals through PI3K";"PI-3K cascade:FGFR4";"PI-3K cascade:FGFR3";"STAT5 Activation";"RHO GTPases Activate WASPs and WAVEs";"RAF/MAP kinase cascade";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"SHC-mediated cascade:FGFR3";"Signaling by FGFR2 in disease";"Spry regulation of FGF signaling";"Negative regulation of FGFR4 signaling";"SOS-mediated signalling";"GAB1 signalosome";"Erythropoietin activates RAS";"NCAM signaling for neurite out-growth";"Activated NTRK2 signals through RAS";"Tie2 Signaling";"Signaling by FGFR4 in disease";"Activated NTRK3 signals through RAS";"GRB2 events in ERBB2 signaling";"MET activates RAP1 and RAC1"
XP_011192818.1	16	Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-190873;Reactome: R-HSA-2132295;Reactome: R-HSA-3928665;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-437239;Reactome: R-HSA-8964038;Reactome: R-HSA-8866427;Reactome: R-HSA-164939;Reactome: R-HSA-196025;Reactome: R-HSA-182218;Reactome: R-HSA-5140745	"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"Gap junction degradation";"MHC class II antigen presentation";"EPH-ephrin mediated repulsion of cells";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1";"LDL clearance";"VLDLR internalisation and degradation";"Nef mediated downregulation of CD28 cell surface expression";"Formation of annular gap junctions";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2"
XP_011179156.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_011187264.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054090983.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054083363.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_011188407.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_028896074.2	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_054087846.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_011177995.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_054082724.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_054087377.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_011184383.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_054089413.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_028894504.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_011190075.2	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_054083580.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_028896921.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_011188254.1	11	Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985	"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4"
XP_011187837.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011185021.1	2	Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_011183823.1	5	KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2	"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism"
XP_054092092.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-5627123	"Clathrin-mediated endocytosis";"RHO GTPases activate PAKs"
XP_011194857.1	18	Reactome: R-HSA-72695;Reactome: R-HSA-6790901;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764	"Formation of the ternary complex, and subsequently, the 43S complex";"rRNA modification in the nucleus and cytosol";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination"
XP_011178575.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054081427.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054086164.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011191899.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829	"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_054086123.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_054081969.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_011188350.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_011178806.2	4	Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-5579026	"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_011176914.1	19	Reactome: R-HSA-5663220;Reactome: R-HSA-4420097;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-5687128;Reactome: R-HSA-5626467;Reactome: R-HSA-2029482;Reactome: R-HSA-182971;Reactome: R-HSA-194840;Reactome: R-HSA-983231;Reactome: R-HSA-8950505;Reactome: R-HSA-5627123;Reactome: R-HSA-418885;Reactome: R-HSA-5625970;Reactome: R-HSA-3928662;Reactome: R-HSA-8964616;Reactome: R-HSA-114604;Reactome: R-HSA-389359;Reactome: R-HSA-428543	"RHO GTPases Activate Formins";"VEGFA-VEGFR2 Pathway";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"MAPK6/MAPK4 signaling";"RHO GTPases activate IQGAPs";"Regulation of actin dynamics for phagocytic cup formation";"EGFR downregulation";"Rho GTPase cycle";"Factors involved in megakaryocyte development and platelet production";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate PAKs";"DCC mediated attractive signaling";"RHO GTPases activate KTN1";"EPHB-mediated forward signaling";"G beta:gamma signalling through CDC42";"GPVI-mediated activation cascade";"CD28 dependent Vav1 pathway";"Inactivation of CDC42 and RAC1"
XP_054089145.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_054090219.1	42	MetaCyc: PWY-6944;KEGG: 00903+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5138;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-6583;MetaCyc: PWY-5109;MetaCyc: PWY-1361;MetaCyc: PWY-7779;MetaCyc: PWY-6435;MetaCyc: PWY-7007;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-7778;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-6883;MetaCyc: PWY-7656;MetaCyc: PWY-7606;MetaCyc: PWY-7216;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6945;MetaCyc: PWY-7654;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-7094;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6946;KEGG: 00623+1.1.1.35;KEGG: 00627+4.2.1.17	"Androstenedione degradation";"Limonene and pinene degradation";"Fatty acid elongation";"Butanoate metabolism";"Propanoate metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Geraniol degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Pyruvate fermentation to butanol I";"Fermentation to 2-methylbutanoate";"Benzoyl-coa degradation I (aerobic)";"Methyl tert-butyl ether degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Phenylalanine metabolism";"Tryptophan metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"2-methylpropene degradation";"Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"Glutaryl-coa degradation";"Pyruvate fermentation to butanol II (engineered)";"Spodoptera littoralis pheromone biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Lysine degradation";"Pyruvate fermentation to hexanol (engineered)";"beta-Alanine metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Valine, leucine and isoleucine degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid salvage";"Caprolactam degradation";"Benzoate degradation";"alpha-Linolenic acid metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Toluene degradation";"Aminobenzoate degradation"
XP_054084153.1	4	MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6	"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"Cysteine and methionine metabolism"
XP_011193781.1	7	Reactome: R-HSA-70268;Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00010+1.2.4.1	"Pyruvate metabolism";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis"
XP_028896352.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_011190465.1	3	Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-6794361	"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Neurexins and neuroligins"
XP_054083669.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_011188174.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054081230.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_011195121.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_054091895.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_011177900.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3108214	"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins"
XP_011191779.2	8	MetaCyc: PWY-6609;MetaCyc: PWY-6611;Reactome: R-HSA-5683826;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179	"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Surfactant metabolism";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Neutrophil degranulation";"Purine metabolism";"Purine deoxyribonucleosides degradation I"
XP_054086448.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054092166.1	5	Reactome: R-HSA-5358346;Reactome: R-HSA-381038;Reactome: R-HSA-901032;Reactome: R-HSA-5362768;MetaCyc: PWY-7511	"Hedgehog ligand biogenesis";"XBP1(S) activates chaperone genes";"ER Quality Control Compartment (ERQC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein ubiquitination"
XP_054081981.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_028893554.2	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_054088102.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-418597	"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"G alpha (z) signalling events"
XP_011192934.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_054082051.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_011181675.2	6	KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761;MetaCyc: PWY-5653;Reactome: R-HSA-196807;MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1	"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_028897499.2	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_011183313.2	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_054084692.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_028901375.1	12	Reactome: R-HSA-9010553;Reactome: R-HSA-72662;Reactome: R-HSA-156827;Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-450408;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-1169408	"Regulation of expression of SLITs and ROBOs";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"L13a-mediated translational silencing of Ceruloplasmin expression";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"mTORC1-mediated signalling";"ISG15 antiviral mechanism"
XP_028899550.2	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_011177658.2	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_011196996.1	9	Reactome: R-HSA-6794361;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-3928662;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324	"Neurexins and neuroligins";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"EPHB-mediated forward signaling";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_054085573.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011177250.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011182582.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_028894622.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_011187561.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054084238.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011182183.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_054087225.1	2	KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608	"Aminoacyl-tRNA biosynthesis";"Platelet degranulation"
XP_011183365.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054083934.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011192437.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_011178067.1	8	MetaCyc: PWY-7197;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184	"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_054083061.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_054081197.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_011193593.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_028896078.1	6	KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920	"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)"
XP_054089281.1	7	KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561;Reactome: R-HSA-2029485;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Choline biosynthesis III";"Role of phospholipids in phagocytosis";"Ether lipid metabolism";"Synthesis of PG";"Synthesis of PA";"Phosphatidate metabolism, as a signaling molecule"
XP_011187660.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation"
XP_054087585.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_011190567.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011196158.2	12	KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;Reactome: R-HSA-3322077;MetaCyc: PWY-7817;Reactome: R-HSA-173599;MetaCyc: PWY-6527;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;KEGG: 00520+2.7.7.9	"Galactose metabolism";"Sucrose biosynthesis II";"Glycogen synthesis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Formation of the active cofactor, UDP-glucuronate";"Stachyose degradation";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_011184081.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_011177729.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6598	"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis"
XP_011190224.2	8	Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841	"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines"
XP_054082781.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-933541;Reactome: R-HSA-936440;Reactome: R-HSA-918233;Reactome: R-HSA-9013973	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6 mediated IRF7 activation";"Negative regulators of DDX58/IFIH1 signaling";"TRAF3-dependent IRF activation pathway";"TICAM1-dependent activation of IRF3/IRF7"
XP_011184275.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_011178410.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_011181256.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054091205.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Sialic acid metabolism";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism"
XP_011185629.1	3	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis"
XP_011178758.2	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054089406.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054090213.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054086129.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_011183011.2	7	MetaCyc: PWY-5941;MetaCyc: PWY-6724;Reactome: R-HSA-6798695;MetaCyc: PWY-6737;MetaCyc: PWY-7238;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.25	"Glycogen degradation II";"Starch degradation II";"Neutrophil degranulation";"Starch degradation V";"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism"
XP_011194181.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_054090424.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_054091558.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054090517.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_028899390.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6811438	"RAB geranylgeranylation";"Intra-Golgi traffic"
XP_054089419.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054081634.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054087592.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_054088458.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_028895196.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054086851.1	8	Reactome: R-HSA-5173105;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629	"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
XP_011188347.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes"
XP_054090896.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_011195725.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_011187556.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_011183151.1	26	Reactome: R-HSA-6811434;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-389977;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-389960;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"Cilium Assembly";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Gap junction assembly";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Kinesins"
XP_011191953.1	3	KEGG: 00230+1.7.3.3;KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691	"Purine metabolism";"Caffeine metabolism";"Urate conversion to allantoin I"
XP_028899351.2	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_011190810.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054083818.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054083089.1	5	Reactome: R-HSA-109704;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001	"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade"
XP_028898342.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054092132.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_011195492.3	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_011176700.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011188926.2	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805	"Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation"
XP_054084434.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011186295.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054081122.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054084689.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_028900134.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011193003.2	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_054081965.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_028894049.2	7	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_011183669.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_011196830.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054086357.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_011185815.2	29	Reactome: R-HSA-176187;Reactome: R-HSA-5358606;Reactome: R-HSA-110320;Reactome: R-HSA-174437;Reactome: R-HSA-68962;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;Reactome: R-HSA-69166;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-3371453;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-5696395;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-912446;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-3371511	"Activation of ATR in response to replication stress";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate from the C-strand";"Activation of the pre-replicative complex";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of HSF1-mediated heat shock response";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Formation of Incision Complex in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"Meiotic recombination";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"HSF1 activation"
XP_054088174.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054088532.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_011181037.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_011193943.2	3	Reactome: R-HSA-8963684;Reactome: R-HSA-156590;Reactome: R-HSA-204174	"Tyrosine catabolism";"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_011196367.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011188503.2	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054081833.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_011184013.2	56	Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Separation of Sister Chromatids"
XP_011180746.2	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_011183437.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_011189992.2	7	Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-5620922	"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_011182051.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_011193183.1	7	Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-8950505;Reactome: R-HSA-6814122	"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_011180684.3	3	Reactome: R-HSA-381426;Reactome: R-HSA-5362798;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation"
XP_028898202.2	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_054082189.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011176987.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_028898830.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054087527.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_054084024.1	5	Reactome: R-HSA-1482883;KEGG: 00561+2.3.1.20;Reactome: R-HSA-6798695;Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20	"Acyl chain remodeling of DAG and TAG";"Glycerolipid metabolism";"Neutrophil degranulation";"Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_054089570.1	12	Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096	"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_054086626.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_054087002.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054090228.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_054085575.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011188095.2	14	MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4	"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Retinoid metabolism and transport";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism"
XP_028901379.1	12	Reactome: R-HSA-9010553;Reactome: R-HSA-72662;Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-1169408	"Regulation of expression of SLITs and ROBOs";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"mTORC1-mediated signalling";"ISG15 antiviral mechanism"
XP_028895780.2	11	Reactome: R-HSA-432040;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-164378	"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Purine metabolism";"G alpha (z) signalling events";"G alpha (s) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation in glucagon signalling"
XP_054084661.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054081794.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011194550.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_054087223.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_011191643.2	14	MetaCyc: PWY-5690;MetaCyc: PWY-561;Reactome: R-HSA-611105;MetaCyc: PWY-7254;KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-6969;MetaCyc: PWY-3781;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;Reactome: R-HSA-71403	"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Butanoate metabolism";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration I (cytochrome c)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)"
XP_054083574.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054086541.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054088407.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_054087583.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_054089860.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_011195995.1	7	KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-7586;MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8;MetaCyc: PWY-882;Reactome: R-HSA-446205	"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose"
XP_028902241.2	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_028894134.1	4	Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_054088350.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_054085664.1	12	MetaCyc: PWY-7343;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.9;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;MetaCyc: PWY-7238;MetaCyc: PWY-7817;KEGG: 00520+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00500+2.7.7.9;KEGG: 00040+2.7.7.9	"UDP-alpha-D-glucose biosynthesis I";"Stachyose degradation";"Galactose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Amino sugar and nucleotide sugar metabolism";"Glycerolipid metabolism";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"Pentose and glucuronate interconversions"
XP_011176421.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054091022.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011187074.1	3	Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine"
XP_054086640.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054090588.1	7	Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_011190469.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_011183027.1	2	MetaCyc: PWY-6938;Reactome: R-HSA-430039	"NADH repair";"mRNA decay by 5' to 3' exoribonuclease"
XP_054091203.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_011178707.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_011184273.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054088312.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_054082497.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_011190424.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_054083092.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054088044.1	12	Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-451308	"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Long-term potentiation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor"
XP_054087712.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_011191097.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_054087589.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_011184311.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
YP_004891168.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_054088876.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_011183818.1	5	KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084	"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_054091953.1	42	KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7778;KEGG: 00360+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-5177;MetaCyc: PWY-6883;MetaCyc: PWY-7606;KEGG: 00903+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;KEGG: 00640+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-1361;MetaCyc: PWY-6435;MetaCyc: PWY-7779;MetaCyc: PWY-6583;MetaCyc: PWY-5109;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-5136;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00592+4.2.1.17;KEGG: 00627+4.2.1.17;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-6863;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-6945	"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"2-methylpropene degradation";"Phenylalanine metabolism";"Tryptophan metabolism";"Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"Spodoptera littoralis pheromone biosynthesis";"Glutaryl-coa degradation";"Pyruvate fermentation to butanol II (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Limonene and pinene degradation";"Fatty acid elongation";"Androstenedione degradation";"Propanoate metabolism";"Butanoate metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Geraniol degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Benzoyl-coa degradation I (aerobic)";"4-hydroxybenzoate biosynthesis III (plants)";"Methyl tert-butyl ether degradation";"Pyruvate fermentation to butanol I";"Fermentation to 2-methylbutanoate";"Fatty acid degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Caprolactam degradation";"Fatty acid salvage";"Fatty acid beta-oxidation II (plant peroxisome)";"Valine, leucine and isoleucine degradation";"Benzoate degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"alpha-Linolenic acid metabolism";"Aminobenzoate degradation";"Toluene degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate fermentation to hexanol (engineered)";"Lysine degradation";"beta-Alanine metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Cholesterol degradation to androstenedione I (cholesterol oxidase)"
XP_011192887.1	56	Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541	"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway"
XP_011185157.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin"
XP_054091216.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_011177491.1	11	KEGG: 05170+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-4420097;KEGG: 04926+2.7.11.1;Reactome: R-HSA-171007	"Human immunodeficiency virus 1 infection";"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Oxidative Stress Induced Senescence";"VEGFA-VEGFR2 Pathway";"Relaxin signaling pathway";"p38MAPK events"
XP_054088904.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_011185210.2	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_054088760.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-8953750;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-111459;Reactome: R-HSA-6803207	"Neutrophil degranulation";"Transcriptional Regulation by E2F6";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_011196235.2	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2"
XP_054091466.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_011183315.2	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_028898667.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_011185618.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054086118.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_054081568.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_054084069.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054082854.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_011186851.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_011178625.1	7	Reactome: R-HSA-212300;Reactome: R-HSA-8943724;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580	"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"HCMV Early Events";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence"
XP_054083271.1	6	MetaCyc: PWY-7238;MetaCyc: PWY-6731;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.1;MetaCyc: PWY-5941;Reactome: R-HSA-70221	"Sucrose biosynthesis II";"Starch degradation III";"Starch degradation V";"Starch and sucrose metabolism";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)"
XP_028895644.2	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_054083365.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054090985.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_011196952.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054089371.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_054083085.1	5	Reactome: R-HSA-109704;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001	"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade"
XP_011180253.2	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_054089415.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_028899603.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011184385.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_011177993.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902	"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation"
XP_011178573.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_054087871.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_011178935.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011183825.1	5	KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084	"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_011182686.1	18	KEGG: 00400+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00330+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00401+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00360+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-5913;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00220+2.6.1.1	"Phenylalanine, tyrosine and tryptophan biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism";"(R)-cysteate degradation";"Novobiocin biosynthesis";"Carbon fixation in photosynthetic organisms";"Sulfolactate degradation III";"Phenylalanine metabolism";"Isoquinoline alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Coenzyme M biosynthesis II";"Arginine biosynthesis"
XP_011191205.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-112043	"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"PLC beta mediated events"
XP_011178496.1	6	Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8951664;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Neddylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines"
XP_011197139.2	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_011193355.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_054087660.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_028901679.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011189620.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_011186576.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_011196029.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"PLC beta mediated events";"G alpha (i) signalling events"
XP_054086125.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_028894641.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011187677.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011187585.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_011186927.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_028899762.2	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_011185022.1	2	KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054089168.1	6	Reactome: R-HSA-114516;Reactome: R-HSA-76005;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-5099900	"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4"
XP_011196094.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_054092091.1	2	Reactome: R-HSA-5627123;Reactome: R-HSA-8856828	"RHO GTPases activate PAKs";"Clathrin-mediated endocytosis"
XP_054083501.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_028896366.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_011189672.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054087106.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497	"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_054081995.1	7	Reactome: R-HSA-3000170;MetaCyc: PWY-7221;Reactome: R-HSA-212676;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-373753;Reactome: R-HSA-6794361	"Syndecan interactions";"Guanosine ribonucleotides de novo biosynthesis";"Dopamine Neurotransmitter Release Cycle";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Nephrin family interactions";"Neurexins and neuroligins"
XP_011189244.2	14	Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-112382	"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex"
XP_011197155.2	5	KEGG: 00240+3.6.1.6;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7210;Reactome: R-HSA-6798695;MetaCyc: PWY-7185	"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Neutrophil degranulation";"UTP and CTP dephosphorylation I"
XP_054091538.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952	"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Long-term potentiation";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions"
XP_054083036.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_011178738.2	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_011189340.2	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50	"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation"
XP_011194589.2	3	KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis";"Heme biosynthesis"
XP_011183699.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_011186637.1	6	Reactome: R-HSA-70221;KEGG: 00500+2.4.1.1;MetaCyc: PWY-5941;MetaCyc: PWY-7238;MetaCyc: PWY-6731;MetaCyc: PWY-6737	"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Glycogen degradation II";"Sucrose biosynthesis II";"Starch degradation III";"Starch degradation V"
XP_011181714.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_011177427.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_011184777.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054092110.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_011183780.2	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_011187840.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011178848.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_011189125.2	4	Reactome: R-HSA-5660862;Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-352230	"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions";"Tryptophan catabolism";"Amino acid transport across the plasma membrane"
XP_011190608.1	4	KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20;MetaCyc: PWY-5331;Reactome: R-HSA-1614558	"Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism";"Taurine biosynthesis I";"Degradation of cysteine and homocysteine"
XP_054088438.1	6	Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-427359;Reactome: R-HSA-73863;Reactome: R-HSA-5250924	"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression"
XP_011187001.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_011178899.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054090626.1	6	Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_011182284.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011189809.1	18	Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925	"Acyl chain remodelling of PS";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG"
XP_054089912.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054084093.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054082052.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_054088101.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-164378	"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (z) signalling events";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling"
XP_054090054.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_028898286.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_054081982.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_011189597.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_054090400.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-76005	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+"
XP_054082484.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_011183408.1	10	KEGG: 00670+2.1.1.45;MetaCyc: PWY-3841;MetaCyc: PWY-7187;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7210;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7184;MetaCyc: PWY-7199;Reactome: R-HSA-69205	"One carbon pool by folate";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleosides salvage";"G1/S-Specific Transcription"
XP_011184710.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_054084691.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054089950.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_011197101.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_028894910.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis"
XP_011184516.1	3	Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23	"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism"
XP_054091869.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_028896351.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_011180546.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_028900068.1	10	Reactome: R-HSA-9636383;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-917729;Reactome: R-HSA-9635644;Reactome: R-HSA-182971;Reactome: R-HSA-5689880;Reactome: R-HSA-8875360;Reactome: R-HSA-432720	"Prevention of phagosomal-lysosomal fusion";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Inhibition of membrane repair";"EGFR downregulation";"Ub-specific processing proteases";"InlB-mediated entry of Listeria monocytogenes into host cell";"Lysosome Vesicle Biogenesis"
XP_011193923.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_028898526.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_054081787.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054082513.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_054083695.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011188006.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_054088028.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_011192665.3	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011184454.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_028898049.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054090962.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946	"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin"
XP_011196909.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_011189788.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_028900474.1	29	Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-77075	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_011179879.2	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_054089282.1	7	KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;MetaCyc: PWY-3561;KEGG: 00564+3.1.4.4	"Ether lipid metabolism";"Synthesis of PG";"Synthesis of PA";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"Choline biosynthesis III";"Glycerophospholipid metabolism"
XP_011192440.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_054082519.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_011182288.1	14	MetaCyc: PWY-7036;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725	"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_028894520.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_028894087.1	9	Reactome: R-HSA-416482;Reactome: R-HSA-5218920;Reactome: R-HSA-193648;Reactome: R-HSA-114604;Reactome: R-HSA-4420097;Reactome: R-HSA-2871796;Reactome: R-HSA-2029482;Reactome: R-HSA-2871809;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"VEGFR2 mediated vascular permeability";"NRAGE signals death through JNK";"GPVI-mediated activation cascade";"VEGFA-VEGFR2 Pathway";"FCERI mediated MAPK activation";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated Ca+2 mobilization";"Rho GTPase cycle"
XP_054089947.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_028896332.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054091824.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_054091863.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_054081250.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_054090784.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054091625.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_011179914.2	4	Reactome: R-HSA-6798695;Reactome: R-HSA-879415;Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Neutrophil degranulation";"Advanced glycosylation endproduct receptor signaling";"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_011184207.1	9	MetaCyc: PWY-6142;KEGG: 00020+6.4.1.1;Reactome: R-HSA-70263;KEGG: 00620+6.4.1.1;Reactome: R-HSA-3371599;MetaCyc: PWY-8086;Reactome: R-HSA-196780;MetaCyc: PWY-6146;KEGG: 00720+6.4.1.1	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Carbon fixation pathways in prokaryotes"
XP_011193010.1	4	Reactome: R-HSA-8950505;Reactome: R-HSA-1268020;Reactome: R-HSA-3371453;Reactome: R-HSA-8949613	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Mitochondrial protein import";"Regulation of HSF1-mediated heat shock response";"Cristae formation"
XP_011182581.2	5	KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;MetaCyc: PWY-7921	"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)"
XP_011190866.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_011185490.2	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_011182528.1	5	Reactome: R-HSA-109704;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001	"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade"
XP_028894688.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054082506.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-163615	"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"G alpha (s) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation"
XP_011190168.2	6	Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938	"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)"
XP_054088790.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_028894023.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_054081549.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054082242.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_011187562.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_054084099.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-9037629	"Voltage gated Potassium channels";"Lewis blood group biosynthesis"
XP_011178734.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_054086852.1	8	KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7921	"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation I (yeast)"
XP_011190851.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_054085290.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011192271.3	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_054087591.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_011197063.2	1	Reactome: R-HSA-5676934	"Protein repair"
XP_011181307.2	15	Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-176034;Reactome: R-HSA-2173796;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167287	"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery"
XP_011181725.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_011192208.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011180321.1	12	Reactome: R-HSA-73863;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-427413;Reactome: R-HSA-1834949;Reactome: R-HSA-5250924;Reactome: R-HSA-73980;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476	"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"NoRC negatively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation"
XP_054092131.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-5689880	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"G alpha (i) signalling events";"Ub-specific processing proteases"
XP_011179136.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054085394.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_011177963.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_011186896.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781	"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression"
XP_011184095.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_054086810.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_011176497.2	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_011178466.1	5	MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;Reactome: R-HSA-197264	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging"
XP_011187616.1	56	Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761	"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_011177489.1	11	KEGG: 05170+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-171007	"Human immunodeficiency virus 1 infection";"activated TAK1 mediates p38 MAPK activation";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"p38MAPK events"
XP_011182914.2	14	Reactome: R-HSA-1483213;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-4419969;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-8053;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-8051	"Synthesis of PE";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Depolymerisation of the Nuclear Lamina";"Ether lipid metabolism";"Triglyceride biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Synthesis of PC";"Anandamide biosynthesis I"
XP_028898134.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_011179528.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_011192501.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_011188884.2	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_054086992.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_011194182.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_011189054.2	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_011194287.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054084710.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_011182484.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054082096.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_028900342.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_011179374.2	57	Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346	"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Neutrophil degranulation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis"
XP_011181723.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_028899425.2	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_011193581.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011197065.2	1	Reactome: R-HSA-5676934	"Protein repair"
XP_011191579.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011177965.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_011181026.1	22	Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-432142;Reactome: R-HSA-5358752;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348	"RAF activation";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Platelet sensitization by LDL";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex"
XP_011184093.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_011184258.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011185554.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_011182052.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054087316.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_011192845.2	1	Reactome: R-HSA-525793	"Myogenesis"
XP_011190054.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_011180453.3	14	MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6433	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_028899712.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_054088920.1	13	MetaCyc: PWY-7141;MetaCyc: PWY-7102;MetaCyc: PWY-6383;MetaCyc: PWY-7182;MetaCyc: PWY-5122;MetaCyc: PWY-7736;MetaCyc: PWY-7659;MetaCyc: PWY-7709;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-6859;MetaCyc: PWY-5123;MetaCyc: PWY-7410;MetaCyc: PWY-7721	"(3S)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Linalool biosynthesis I";"Geranyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"Viridicatumtoxin biosynthesis";"(3R)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"All-trans-farnesol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Methyl phomopsenoate biosynthesis"
XP_054081121.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_011182929.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011176781.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054082470.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_011181801.2	5	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport"
XP_011176548.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054081999.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054081886.1	6	Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6364;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism"
XP_011189866.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_011188551.3	3	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-111367	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs"
XP_054091021.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_011177794.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_011184044.2	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_011188155.2	4	KEGG: 00040+2.7.1.17;MetaCyc: PWY-4261;Reactome: R-HSA-5661270;KEGG: 00561+2.7.1.30	"Pentose and glucuronate interconversions";"Glycerol degradation I";"Formation of xylulose-5-phosphate";"Glycerolipid metabolism"
XP_054091623.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_011182374.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_011179484.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_011195427.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054084336.1	19	KEGG: 00630+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00680+1.1.1.37;KEGG: 00270+1.1.1.37;Reactome: R-HSA-71403;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-8086;MetaCyc: PWY-6728;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-561;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-5913;Reactome: R-HSA-70263	"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methane metabolism";"Cysteine and methionine metabolism";"Citric acid cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"Carbon fixation in photosynthetic organisms";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Partial TCA cycle (obligate autotrophs)";"Gluconeogenesis"
XP_054088311.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_011187106.1	11	Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-5689880;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-6804756	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Ub-specific processing proteases";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation"
XP_011192404.2	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_011191538.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_011185643.2	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_054085959.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_054087001.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_028896128.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_011186831.1	8	MetaCyc: PWY-5394;KEGG: 00790+1.14.16.2;MetaCyc: PWY-3581;MetaCyc: PWY-5049;KEGG: 00950+1.14.16.2;KEGG: 00350+1.14.16.2;Reactome: R-HSA-209905;MetaCyc: PWY-6133	"Betalamic acid biosynthesis";"Folate biosynthesis";"(S)-reticuline biosynthesis I";"Rosmarinic acid biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Catecholamine biosynthesis";"(S)-reticuline biosynthesis II"
XP_011183682.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_011184904.2	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_054086542.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_028901117.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_028895574.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054086637.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054084662.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_011177492.1	11	Reactome: R-HSA-171007;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1	"p38MAPK events";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Oxidative Stress Induced Senescence";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection"
XP_011193060.2	20	MetaCyc: PWY-7007;MetaCyc: PWY-5136;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-7337;MetaCyc: PWY-6920;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7858;MetaCyc: PWY-6837;MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-735	"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis"
XP_011180571.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_054084095.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_011190657.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054091939.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_011176544.2	8	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_054083110.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-5667;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51	"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism"
XP_011188766.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_011186852.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_028896711.2	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_028894402.2	7	Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_011189448.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_011185649.2	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_054087711.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054087616.1	19	Reactome: R-HSA-418885;Reactome: R-HSA-5625970;Reactome: R-HSA-983231;Reactome: R-HSA-5627123;Reactome: R-HSA-8950505;Reactome: R-HSA-8964616;Reactome: R-HSA-114604;Reactome: R-HSA-3928662;Reactome: R-HSA-389359;Reactome: R-HSA-428543;Reactome: R-HSA-4420097;Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-5687128;Reactome: R-HSA-182971;Reactome: R-HSA-194840;Reactome: R-HSA-5626467;Reactome: R-HSA-2029482	"DCC mediated attractive signaling";"RHO GTPases activate KTN1";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases activate PAKs";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"G beta:gamma signalling through CDC42";"GPVI-mediated activation cascade";"EPHB-mediated forward signaling";"CD28 dependent Vav1 pathway";"Inactivation of CDC42 and RAC1";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate Formins";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"MAPK6/MAPK4 signaling";"EGFR downregulation";"Rho GTPase cycle";"RHO GTPases activate IQGAPs";"Regulation of actin dynamics for phagocytic cup formation"
XP_054081167.1	5	Reactome: R-HSA-75955;Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_011195745.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_011183739.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_011187249.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_011185097.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Aggrephagy";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_011179378.1	6	Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6798695;Reactome: R-HSA-6782135	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Neutrophil degranulation";"Dual incision in TC-NER"
XP_054085209.1	10	KEGG: 00520+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-7328;Reactome: R-HSA-5609977;MetaCyc: PWY-6317	"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Stachyose degradation";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose degradation I (Leloir pathway)"
XP_054092036.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_011192240.2	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_054083693.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_011180670.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_011179875.2	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_054086213.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_054091067.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_028896163.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_054081993.1	7	Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-212676;MetaCyc: PWY-7221;Reactome: R-HSA-3000170;Reactome: R-HSA-6794361;Reactome: R-HSA-373753	"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Dopamine Neurotransmitter Release Cycle";"Guanosine ribonucleotides de novo biosynthesis";"Syndecan interactions";"Neurexins and neuroligins";"Nephrin family interactions"
XP_011177485.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_011189304.1	6	MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632	"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_011181462.1	16	Reactome: R-HSA-5602498;Reactome: R-HSA-209543;Reactome: R-HSA-5603041;Reactome: R-HSA-9020702;Reactome: R-HSA-6811558;Reactome: R-HSA-1236974;Reactome: R-HSA-975155;Reactome: R-HSA-1810476;Reactome: R-HSA-166058;Reactome: R-HSA-5602680;Reactome: R-HSA-3134963;Reactome: R-HSA-975138;Reactome: R-HSA-5603037;Reactome: R-HSA-975110;Reactome: R-HSA-1257604;Reactome: R-HSA-975871	"MyD88 deficiency (TLR2/4)";"p75NTR recruits signalling complexes";"IRAK4 deficiency (TLR2/4)";"Interleukin-1 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ER-Phagosome pathway";"MyD88 dependent cascade initiated on endosome";"RIP-mediated NFkB activation via ZBP1";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 deficiency (TLR5)";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"IRAK4 deficiency (TLR5)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"PIP3 activates AKT signaling";"MyD88 cascade initiated on plasma membrane"
XP_011177839.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_011190125.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_011182923.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_011183300.1	24	Reactome: R-HSA-418597;Reactome: R-HSA-381676;Reactome: R-HSA-6814122;Reactome: R-HSA-418217;Reactome: R-HSA-202040;Reactome: R-HSA-163359;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-420092;Reactome: R-HSA-418555;Reactome: R-HSA-416482;Reactome: R-HSA-456926;Reactome: R-HSA-8964315;Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-500657	"G alpha (z) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PLC beta";"G-protein activation";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-type ligand receptors";"G alpha (s) signalling events";"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through BTK";"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors"
XP_011182497.3	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054085734.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_011193793.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-194840	"RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle"
XP_011183457.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054091410.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054082799.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_011182674.2	3	Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_011191935.1	13	MetaCyc: PWY-7184;KEGG: 00770+3.6.1.9;Reactome: R-HSA-74259;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00500+3.6.1.9;KEGG: 00230+3.6.1.66;MetaCyc: PWY-6545;MetaCyc: PWY-7821;KEGG: 00240+3.6.1.9	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pantothenate and CoA biosynthesis";"Purine catabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Starch and sucrose metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Tunicamycin biosynthesis";"Pyrimidine metabolism"
XP_054089803.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_011184099.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_011179421.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_054083399.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054090866.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_011189123.2	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_011180239.2	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_054091452.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_028901995.2	5	Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-936964	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"