Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_016995910.2	13	Reactome: R-HSA-8948216;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-186797;Reactome: R-HSA-1474244;Reactome: R-HSA-2022090;Reactome: R-HSA-3000157;Reactome: R-HSA-216083;Reactome: R-HSA-1442490;Reactome: R-HSA-419037	"Collagen chain trimerization";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Signaling by PDGF";"Extracellular matrix organization";"Assembly of collagen fibrils and other multimeric structures";"Laminin interactions";"Integrin cell surface interactions";"Collagen degradation";"NCAM1 interactions"
XP_017009477.2	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_017009453.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090	"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures"
XP_016994651.2	13	MetaCyc: PWY-7410;MetaCyc: PWY-6859;MetaCyc: PWY-7659;MetaCyc: PWY-6383;MetaCyc: PWY-7102;MetaCyc: PWY-7709;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-5123;MetaCyc: PWY-7141;MetaCyc: PWY-5122;MetaCyc: PWY-7736;MetaCyc: PWY-7721;MetaCyc: PWY-7182	"Ipsdienol biosynthesis";"All-trans-farnesol biosynthesis";"Viridicatumtoxin biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"(3R)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3S)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"Methyl phomopsenoate biosynthesis";"Linalool biosynthesis I"
XP_017008984.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_017012673.2	8	Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712	"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"ATP biosynthesis";"Photosynthesis";"Oxidative phosphorylation";"Ion channel transport"
XP_016992995.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_044250108.1	5	KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00020+4.2.1.3	"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport";"Citrate cycle (TCA cycle)"
XP_017000145.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_017004115.2	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_044250191.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_016996242.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_017001066.2	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_017000387.2	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_017002120.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_017008887.1	57	Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-532668;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541	"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Separation of Sister Chromatids";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway"
XP_016994710.2	7	MetaCyc: PWY-7255;KEGG: 00270+6.3.2.2;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403;MetaCyc: PWY-6840;MetaCyc: PWY-8043	"Ergothioneine biosynthesis I (bacteria)";"Cysteine and methionine metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism";"Glutathione synthesis and recycling";"Homoglutathione biosynthesis";"Ophthalmate biosynthesis"
XP_016999966.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044249683.1	42	Reactome: R-HSA-2559580;Reactome: R-HSA-1221632;Reactome: R-HSA-977225;Reactome: R-HSA-2559586;Reactome: R-HSA-110329;Reactome: R-HSA-9610379;Reactome: R-HSA-5625886;Reactome: R-HSA-5617472;Reactome: R-HSA-3214842;Reactome: R-HSA-1912408;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-69473;Reactome: R-HSA-3214858;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-73728;Reactome: R-HSA-912446;Reactome: R-HSA-427389;Reactome: R-HSA-73772;Reactome: R-HSA-5693607;Reactome: R-HSA-3214841;Reactome: R-HSA-8939236;Reactome: R-HSA-5578749;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-212300;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-9609690;Reactome: R-HSA-8936459;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222	"Oxidative Stress Induced Senescence";"Meiotic synapsis";"Amyloid fiber formation";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"HCMV Late Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HDMs demethylate histones";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"G2/M DNA damage checkpoint";"RMTs methylate histone arginines";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"RNA Polymerase I Promoter Opening";"Meiotic recombination";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape";"Processing of DNA double-strand break ends";"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation by small RNAs";"DNA methylation";"Estrogen-dependent gene expression";"HATs acetylate histones";"PRC2 methylates histones and DNA";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"HCMV Early Events";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis"
XP_017001865.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_017004411.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016996984.2	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_016999033.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_016995504.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_044250675.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_017010798.2	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_016998267.2	5	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_016993813.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_017006103.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017002114.2	18	Reactome: R-HSA-1482839;MetaCyc: PWY-7409;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;Reactome: R-HSA-1483166	"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Synthesis of PA"
XP_016998997.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_017008256.2	13	Reactome: R-HSA-5607763;Reactome: R-HSA-2871809;Reactome: R-HSA-139853;Reactome: R-HSA-114508;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-983695;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-5218921;Reactome: R-HSA-112043;Reactome: R-HSA-5578775;Reactome: R-HSA-422356	"CLEC7A (Dectin-1) induces NFAT activation";"FCERI mediated Ca+2 mobilization";"Elevation of cytosolic Ca2+ levels";"Effects of PIP2 hydrolysis";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"VEGFR2 mediated cell proliferation";"PLC beta mediated events";"Ion homeostasis";"Regulation of insulin secretion"
XP_044251267.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_016994689.2	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_017016310.2	16	Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-141430	"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex"
XP_017016288.2	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_044249779.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017009949.2	13	Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823	"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation"
XP_044250640.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-426117	"Ion transport by P-type ATPases";"Cation-coupled Chloride cotransporters"
XP_044251643.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_017007666.2	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_017000689.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044251527.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_016993996.2	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_044248924.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_044250003.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017005317.1	2	Reactome: R-HSA-8876725;Reactome: R-HSA-611105	"Protein methylation";"Respiratory electron transport"
XP_017012626.2	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_017001386.2	6	Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226	"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017011854.2	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_017010887.2	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-5362798	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell"
XP_017007075.2	2	Reactome: R-HSA-532668;Reactome: R-HSA-6798695	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation"
XP_016997325.1	1	Reactome: R-HSA-419771	"Opsins"
XP_017005160.2	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_017009514.2	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_044251953.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_016992770.2	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_017007187.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_017013157.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016996986.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016998510.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_017007906.2	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_044251951.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_044248679.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_017005338.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_017006216.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823	"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation"
XP_044251292.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_017006956.2	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_017008175.2	3	Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_017012708.2	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_017002472.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016998075.2	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
XP_017003851.2	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
XP_017011154.2	8	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-438066	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_017007330.2	9	MetaCyc: PWY-7115;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-5744;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-7117	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_044248582.1	18	KEGG: 00230+2.7.4.6;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7176;MetaCyc: PWY-7227;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7187;MetaCyc: PWY-7205;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis"
XP_016994775.2	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_017006669.2	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_017008275.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044249847.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_044249444.1	5	Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_044251060.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017011658.2	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_017006474.2	8	Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-69183	"DNA replication initiation";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand"
XP_044251426.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_017008666.2	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_017000249.2	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_017015923.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016997005.2	19	KEGG: 00270+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-561;Reactome: R-HSA-71403;MetaCyc: PWY-7115;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5392	"Cysteine and methionine metabolism";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methane metabolism";"Partial TCA cycle (obligate autotrophs)";"Glyoxylate and dicarboxylate metabolism";"Reductive TCA cycle II"
XP_017007133.2	29	KEGG: 00071+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-3162;MetaCyc: PWY-7396;MetaCyc: PWY-5076;MetaCyc: PWY-6802;MetaCyc: PWY-7013;MetaCyc: PWY-6587;MetaCyc: PWY-6333;KEGG: 00260+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-5480;MetaCyc: PWY-6342;KEGG: 00592+1.1.1.1;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5057;KEGG: 00982+1.1.1.1;MetaCyc: PWY-5751;MetaCyc: PWY-6871;KEGG: 00010+1.1.1.1;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5082;KEGG: 00980+1.1.1.1;KEGG: 00830+1.1.1.1;MetaCyc: PWY-6313;MetaCyc: PWY-7111;MetaCyc: PWY-5078;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5486	"Fatty acid degradation";"Chitin degradation to ethanol";"L-tryptophan degradation V (side chain pathway)";"Butanol and isobutanol biosynthesis (engineered)";"L-leucine degradation III";"Salidroside biosynthesis";"(S)-propane-1,2-diol degradation";"Pyruvate fermentation to ethanol III";"Acetaldehyde biosynthesis I";"Glycine, serine and threonine metabolism";"L-phenylalanine degradation III";"Pyruvate fermentation to ethanol I";"Noradrenaline and adrenaline degradation";"alpha-Linolenic acid metabolism";"Tyrosine metabolism";"L-valine degradation II";"Drug metabolism - cytochrome P450";"Phenylethanol biosynthesis";"3-methylbutanol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Chloroalkane and chloroalkene degradation";"L-methionine degradation III";"Metabolism of xenobiotics by cytochrome P450";"Retinol metabolism";"Serotonin degradation";"Pyruvate fermentation to isobutanol (engineered)";"L-isoleucine degradation II";"Naphthalene degradation";"Pyruvate fermentation to ethanol II"
XP_017003106.2	6	Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule"
XP_017008757.2	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_017011175.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016997060.2	4	KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661;MetaCyc: PWY-6987;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_016996472.2	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events"
XP_017007591.2	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_044249182.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_017012058.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016995724.2	5	Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_016997255.2	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_017003797.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044250140.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017002168.2	11	Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-163615	"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"Glucagon signaling in metabolic regulation";"PKA activation"
XP_017013412.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_017015239.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_017004659.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016997513.2	8	KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway"
XP_017005353.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044249538.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016994679.2	18	KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;MetaCyc: PWY-8051;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482801	"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PS"
XP_044249984.1	3	MetaCyc: PWY-1801;Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12	"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation";"Methane metabolism"
XP_017014351.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017015150.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118	"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors"
XP_017003907.2	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_017015089.1	179	Reactome: R-HSA-5689877;Reactome: R-HSA-205043;Reactome: R-HSA-9613829;Reactome: R-HSA-5696400;Reactome: R-HSA-1358803;Reactome: R-HSA-5693607;Reactome: R-HSA-5610785;Reactome: R-HSA-2173796;Reactome: R-HSA-9013507;Reactome: R-HSA-1234176;Reactome: R-HSA-3134975;Reactome: R-HSA-450302;Reactome: R-HSA-174154;Reactome: R-HSA-5357956;Reactome: R-HSA-9633012;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-162588;Reactome: R-HSA-5656121;Reactome: R-HSA-179409;Reactome: R-HSA-9637628;Reactome: R-HSA-5654733;Reactome: R-HSA-2559585;Reactome: R-HSA-977225;Reactome: R-HSA-445989;Reactome: R-HSA-8875360;Reactome: R-HSA-5607761;Reactome: R-HSA-975163;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-400253;Reactome: R-HSA-6782210;Reactome: R-HSA-5693565;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-2408557;Reactome: R-HSA-69231;Reactome: R-HSA-349425;Reactome: R-HSA-168927;Reactome: R-HSA-1169408;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-937072;Reactome: R-HSA-6783310;Reactome: R-HSA-6804760;Reactome: R-HSA-2559582;Reactome: R-HSA-1236974;Reactome: R-HSA-532668;Reactome: R-HSA-4608870;Reactome: R-HSA-5654732;Reactome: R-HSA-8863795;Reactome: R-HSA-5675482;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-3769402;Reactome: R-HSA-69601;Reactome: R-HSA-110320;Reactome: R-HSA-936440;Reactome: R-HSA-202424;Reactome: R-HSA-936964;Reactome: R-HSA-8876493;Reactome: R-HSA-6807004;Reactome: R-HSA-2467813;Reactome: R-HSA-1236382;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-4641263;Reactome: R-HSA-72689;Reactome: R-HSA-187577;Reactome: R-HSA-72706;Reactome: R-HSA-9645460;Reactome: R-HSA-5655862;Reactome: R-HSA-2559580;Reactome: R-HSA-211733;Reactome: R-HSA-2173791;Reactome: R-HSA-9033241;Reactome: R-HSA-9013973;Reactome: R-HSA-209560;Reactome: R-HSA-917937;Reactome: R-HSA-9646399;Reactome: R-HSA-192823;Reactome: R-HSA-8856828;Reactome: R-HSA-5689896;Reactome: R-HSA-209543;Reactome: R-HSA-168638;Reactome: R-HSA-983168;Reactome: R-HSA-174490;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-5684264;Reactome: R-HSA-2122947;Reactome: R-HSA-937039;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-1799339;Reactome: R-HSA-5656169;Reactome: R-HSA-5357905;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-2672351;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-1253288;Reactome: R-HSA-3785653;Reactome: R-HSA-6804756;Reactome: R-HSA-8856825;Reactome: R-HSA-5654726;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-5696397;Reactome: R-HSA-975956;Reactome: R-HSA-182971;Reactome: R-HSA-5678895;Reactome: R-HSA-975957;Reactome: R-HSA-1295596;Reactome: R-HSA-937041;Reactome: R-HSA-2173795;Reactome: R-HSA-110314;Reactome: R-HSA-8948751;Reactome: R-HSA-8948747;Reactome: R-HSA-180585;Reactome: R-HSA-174048;Reactome: R-HSA-8854050;Reactome: R-HSA-69541;Reactome: R-HSA-912631;Reactome: R-HSA-8951664;Reactome: R-HSA-9636383;Reactome: R-HSA-8849469;Reactome: R-HSA-8866652;Reactome: R-HSA-937042;Reactome: R-HSA-175474;Reactome: R-HSA-975144;Reactome: R-HSA-5205685;Reactome: R-HSA-201681;Reactome: R-HSA-2173788;Reactome: R-HSA-5696395;Reactome: R-HSA-5610783;Reactome: R-HSA-6781823;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-8866654;Reactome: R-HSA-3322077;Reactome: R-HSA-5696394;Reactome: R-HSA-9615710;Reactome: R-HSA-2122948;Reactome: R-HSA-5676590;Reactome: R-HSA-450321;Reactome: R-HSA-5689603;Reactome: R-HSA-2691232;Reactome: R-HSA-2565942;Reactome: R-HSA-5689880;Reactome: R-HSA-69017;Reactome: R-HSA-917729;Reactome: R-HSA-2871837;Reactome: R-HSA-110312;Reactome: R-HSA-4641257;Reactome: R-HSA-5654727;Reactome: R-HSA-2979096;Reactome: R-HSA-6782135;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-168928;Reactome: R-HSA-156902;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-72764;Reactome: R-HSA-382556;Reactome: R-HSA-5685942;Reactome: R-HSA-9014325;Reactome: R-HSA-901032;Reactome: R-HSA-5675221;Reactome: R-HSA-975110;Reactome: R-HSA-5689901	"Josephin domain DUBs";"NRIF signals cell death from the nucleus";"Chaperone Mediated Autophagy";"Dual Incision in GG-NER";"Downregulation of ERBB2:ERBB3 signaling";"Processing of DNA double-strand break ends";"GLI3 is processed to GLI3R by the proteasome";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of innate immune responses to cytosolic DNA";"activated TAK1 mediates p38 MAPK activation";"APC/C:Cdc20 mediated degradation of Securin";"TNFR1-induced NFkappaB signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Budding and maturation of HIV virion";"Translesion synthesis by POLI";"APC-Cdc20 mediated degradation of Nek2A";"Modulation by Mtb of host immune system";"Negative regulation of FGFR4 signaling";"Oncogene Induced Senescence";"Amyloid fiber formation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"InlB-mediated entry of Listeria monocytogenes into host cell";"Dectin-1 mediated noncanonical NF-kB signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Circadian Clock";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Selenocysteine synthesis";"Cyclin D associated events in G1";"Autodegradation of the E3 ubiquitin ligase COP1";"TICAM1, RIP1-mediated IKK complex recruitment";"ISG15 antiviral mechanism";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Methylation";"Senescence-Associated Secretory Phenotype (SASP)";"ER-Phagosome pathway";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Asymmetric localization of PCP proteins";"Negative regulation of FGFR3 signaling";"Downregulation of ERBB2 signaling";"Regulation of necroptotic cell death";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Deactivation of the beta-catenin transactivating complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Translesion Synthesis by POLH";"Negative regulators of DDX58/IFIH1 signaling";"Downstream TCR signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"InlA-mediated entry of Listeria monocytogenes into host cells";"Negative regulation of MET activity";"Separation of Sister Chromatids";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Regulation of FZD by ubiquitination";"Formation of a pool of free 40S subunits";"SCF(Skp2)-mediated degradation of p27/p21";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Alpha-protein kinase 1 signaling pathway";"Translesion synthesis by POLK";"Oxidative Stress Induced Senescence";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Peroxisomal protein import";"TICAM1-dependent activation of IRF3/IRF7";"NF-kB is activated and signals survival";"Iron uptake and transport";"Aggrephagy";"Viral mRNA Translation";"Clathrin-mediated endocytosis";"Ovarian tumor domain proteases";"p75NTR recruits signalling complexes";"NOD1/2 Signaling Pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Membrane binding and targetting of GAG proteins";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"IRAK1 recruits IKK complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"SRP-dependent cotranslational protein targeting to membrane";"Termination of translesion DNA synthesis";"Regulation of TNFR1 signaling";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Stimuli-sensing channels";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Downregulation of ERBB4 signaling";"Myoclonic epilepsy of Lafora";"Regulation of TP53 Activity through Phosphorylation";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of FGFR1 signaling";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"EGFR downregulation";"Defective CFTR causes cystic fibrosis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Spry regulation of FGF signaling";"IKK complex recruitment mediated by RIP1";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of PTEN stability and activity";"Regulation of PTEN localization";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Cyclin B";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Stabilization of p53";"Regulation of signaling by CBL";"Neddylation";"Prevention of phagosomal-lysosomal fusion";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"IRAK2 mediated activation of TAK1 complex";"Assembly Of The HIV Virion";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Pink/Parkin Mediated Mitophagy";"TCF dependent signaling in response to WNT";"Downregulation of TGF-beta receptor signaling";"Formation of Incision Complex in GG-NER";"Degradation of GLI2 by the proteasome";"Formation of TC-NER Pre-Incision Complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"E3 ubiquitin ligases ubiquitinate target proteins";"Glycogen synthesis";"DNA Damage Recognition in GG-NER";"Late endosomal microautophagy";"Activated NOTCH1 Transmits Signal to the Nucleus";"NIK-->noncanonical NF-kB signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"UCH proteinases";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"Ub-specific processing proteases";"CDK-mediated phosphorylation and removal of Cdc6";"Endosomal Sorting Complex Required For Transport (ESCRT)";"FCERI mediated NF-kB activation";"Translesion synthesis by REV1";"Degradation of AXIN";"Negative regulation of FGFR2 signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Dual incision in TC-NER";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Peptide chain elongation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Eukaryotic Translation Termination";"ABC-family proteins mediated transport";"HDR through Homologous Recombination (HRR)";"TICAM1,TRAF6-dependent induction of TAK1 complex";"ER Quality Control Compartment (ERQC)";"Negative regulation of MAPK pathway";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Metalloprotease DUBs"
XP_044252219.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5972;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7724	"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_017011957.2	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_016993239.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017007246.2	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_044251533.1	6	MetaCyc: PWY-6364;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism"
XP_017013447.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_016998904.2	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_017007770.2	5	Reactome: R-HSA-901032;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;MetaCyc: PWY-7511;Reactome: R-HSA-381038	"ER Quality Control Compartment (ERQC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Protein ubiquitination";"XBP1(S) activates chaperone genes"
XP_016993810.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_017014195.2	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_016993873.2	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_017005412.2	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_017009295.1	11	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-2559580;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"Oxidative Stress Induced Senescence";"PI3K-Akt signaling pathway"
XP_017013382.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_044250328.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_017008299.2	4	Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389	"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_016999632.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044251382.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_016994378.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_017010660.2	8	MetaCyc: PWY-5049;Reactome: R-HSA-209905;MetaCyc: PWY-3581;KEGG: 00350+1.14.16.2;MetaCyc: PWY-5394;KEGG: 00790+1.14.16.2;MetaCyc: PWY-6133;KEGG: 00950+1.14.16.2	"Rosmarinic acid biosynthesis II";"Catecholamine biosynthesis";"(S)-reticuline biosynthesis I";"Tyrosine metabolism";"Betalamic acid biosynthesis";"Folate biosynthesis";"(S)-reticuline biosynthesis II";"Isoquinoline alkaloid biosynthesis"
XP_016998426.2	5	Reactome: R-HSA-8856828;Reactome: R-HSA-432722;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440	"Clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network"
XP_017011878.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_017015027.2	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis"
XP_017009416.2	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_016992690.2	8	Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483	"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs"
XP_017000104.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017008808.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016995451.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016999915.2	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_017001769.2	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_044250143.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016997922.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016996515.2	56	Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-68949	"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Degradation of AXIN";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin"
XP_017013525.2	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_044249649.1	42	Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-8939236;Reactome: R-HSA-912446;Reactome: R-HSA-427389;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-5693607;Reactome: R-HSA-9616222;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-8936459;Reactome: R-HSA-171306;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-3214842;Reactome: R-HSA-1912408;Reactome: R-HSA-110329;Reactome: R-HSA-5625886;Reactome: R-HSA-9610379;Reactome: R-HSA-2559586;Reactome: R-HSA-977225;Reactome: R-HSA-1221632;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-2299718;Reactome: R-HSA-5250924;Reactome: R-HSA-5693565;Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-5693571;Reactome: R-HSA-201722;Reactome: R-HSA-3214815;Reactome: R-HSA-3214858;Reactome: R-HSA-69473	"Estrogen-dependent gene expression";"DNA methylation";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Meiotic recombination";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"Processing of DNA double-strand break ends";"Transcriptional regulation of granulopoiesis";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Packaging Of Telomere Ends";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"HCMV Early Events";"PRC2 methylates histones and DNA";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDMs demethylate histones";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged pyrimidine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HCMV Late Events";"DNA Damage/Telomere Stress Induced Senescence";"Amyloid fiber formation";"Meiotic synapsis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Condensation of Prophase Chromosomes";"B-WICH complex positively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Nonhomologous End-Joining (NHEJ)";"Formation of the beta-catenin:TCF transactivating complex";"HDACs deacetylate histones";"RMTs methylate histone arginines";"G2/M DNA damage checkpoint"
XP_017012880.2	9	MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590	"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"Glutathione conjugation"
XP_016995545.2	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_044251952.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_017000053.2	2	Reactome: R-HSA-8983711;Reactome: R-HSA-909733	"OAS antiviral response";"Interferon alpha/beta signaling"
XP_044248838.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_016998106.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016995328.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_017011248.2	24	Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Gap junction assembly";"Kinesins";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"HCMV Early Events";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors"
XP_017006737.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_017015012.2	27	Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-159227	"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"snRNP Assembly";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA"
XP_016997788.2	4	KEGG: 00900+2.5.1.87;Reactome: R-HSA-446199;MetaCyc: PWY-6129;Reactome: R-HSA-4755609	"Terpenoid backbone biosynthesis";"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59"
XP_017015136.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_017006780.2	10	KEGG: 00010+2.7.2.3;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-1042;KEGG: 00710+2.7.2.3;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-5484	"Glycolysis / Gluconeogenesis";"Glycolysis";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)"
XP_044250548.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_017002912.2	6	Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_044250080.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_017002378.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017000609.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044248955.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_017013007.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_017009866.2	15	Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723	"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation"
XP_017012134.2	3	MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7	"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_017001299.2	11	Reactome: R-HSA-163680;KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04926+2.7.11.1	"AMPK inhibits chREBP transcriptional activation activity";"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"FOXO-mediated transcription of cell death genes";"Relaxin signaling pathway"
XP_017015167.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-390471	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis"
XP_017008915.2	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_044251278.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_017011208.2	6	MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_017003920.2	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_017004262.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017012558.2	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6787450	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_017001830.2	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_016999747.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_016995233.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017012745.2	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_044250355.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_017010011.2	14	Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5696400	"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER"
XP_017003773.1	26	Reactome: R-HSA-389977;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-190861;Reactome: R-HSA-983189	"Post-chaperonin tubulin folding pathway";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Gap junction assembly";"Kinesins"
XP_017000159.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016998694.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_017008990.2	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_017014986.2	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_017008172.2	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_016994497.2	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_017008123.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_016997762.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016997789.2	4	KEGG: 00900+2.5.1.87;Reactome: R-HSA-446199;MetaCyc: PWY-6129;Reactome: R-HSA-4755609	"Terpenoid backbone biosynthesis";"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59"
XP_017003210.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017015658.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_017005570.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016995501.2	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_016995058.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_017008473.2	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_016999431.2	4	MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_017009976.2	6	Reactome: R-HSA-196780;MetaCyc: PWY-6987;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181	"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_017003948.2	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism"
XP_016994498.2	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_016997206.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017000827.2	3	Reactome: R-HSA-5626978;Reactome: R-HSA-193681;Reactome: R-HSA-1660662	"TNFR1-mediated ceramide production";"Ceramide signalling";"Glycosphingolipid metabolism"
XP_017003318.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_017002085.2	5	KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_017015026.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_044249319.1	14	Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167152	"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_017005392.2	5	Reactome: R-HSA-936440;Reactome: R-HSA-918233;Reactome: R-HSA-9013973;Reactome: R-HSA-933541;Reactome: R-HSA-936964	"Negative regulators of DDX58/IFIH1 signaling";"TRAF3-dependent IRF activation pathway";"TICAM1-dependent activation of IRF3/IRF7";"TRAF6 mediated IRF7 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_017012942.2	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_016993550.2	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_017006811.2	11	Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-5689880;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"Ub-specific processing proteases";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome"
XP_044249121.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_044248887.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_017014450.2	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_017004393.2	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_017006649.2	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_017010072.1	18	KEGG: 00280+1.8.1.4;KEGG: 00640+1.8.1.4;Reactome: R-HSA-6783984;MetaCyc: PWY-5046;KEGG: 00310+1.8.1.4;KEGG: 00620+1.8.1.4;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.8.1.4;KEGG: 00010+1.8.1.4;KEGG: 00260+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00020+1.8.1.4;Reactome: R-HSA-71403;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Glycine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Lysine degradation";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Lysine catabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Branched-chain amino acid catabolism"
XP_044251261.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_016998373.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017003018.2	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_017004176.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016997490.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044250362.1	2	KEGG: 00514+2.4.1.222;Reactome: R-HSA-1912420	"Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in Golgi"
XP_017000046.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044250906.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_017008746.2	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_017001640.2	5	MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I"
XP_017004768.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_017001112.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_017010490.2	25	Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-380270;Reactome: R-HSA-983189;Reactome: R-HSA-190840;Reactome: R-HSA-8852276	"RHO GTPases Activate Formins";"Aggrephagy";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Gap junction assembly";"Recruitment of mitotic centrosome proteins and complexes";"Kinesins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_044249980.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_044248750.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017001675.1	17	Reactome: R-HSA-6804756;Reactome: R-HSA-2467813;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2500257;Reactome: R-HSA-174178;KEGG: 04714+2.7.11.1;Reactome: R-HSA-141444;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9648025;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9022692;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"Regulation of TP53 Activity through Phosphorylation";"Separation of Sister Chromatids";"Relaxin signaling pathway";"Resolution of Sister Chromatid Cohesion";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Thermogenesis";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"EML4 and NUDC in mitotic spindle formation";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Regulation of MECP2 expression and activity";"mTOR signaling pathway";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_017011273.1	16	Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-174184	"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_016997312.2	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_017001102.2	8	Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-176187	"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress"
XP_044249316.1	14	Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-6796648	"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes"
XP_017014566.2	29	Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-76042	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_017014116.1	10	Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-2151201;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-611105	"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Respiratory electron transport"
XP_017008140.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044251004.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_016999652.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_017010021.1	52	Reactome: R-HSA-112382;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-1834949;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-72165;Reactome: R-HSA-5601884;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-749476;Reactome: R-HSA-203927;Reactome: R-HSA-8851708;Reactome: R-HSA-73779;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-76061;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-72163;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-76066;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-5617472;Reactome: R-HSA-76071;Reactome: R-HSA-168325;Reactome: R-HSA-6782210;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-5250924;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-167152	"Formation of RNA Pol II elongation complex";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"Cytosolic sensors of pathogen-associated DNA";"HIV Transcription Initiation";"mRNA Capping";"RNA Polymerase I Promoter Escape";"mRNA Splicing - Minor Pathway";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Abortive And Retractive Initiation";"MicroRNA (miRNA) biogenesis";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcription of the HIV genome";"FGFR2 alternative splicing";"mRNA Splicing - Major Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Viral Messenger RNA Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"B-WICH complex positively regulates rRNA expression";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_044249755.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044249597.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017008286.2	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_017008574.2	5	KEGG: 00240+3.6.1.6;MetaCyc: PWY-7185;MetaCyc: PWY-7210;Reactome: R-HSA-6798695;KEGG: 00230+3.6.1.6	"Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Neutrophil degranulation";"Purine metabolism"
XP_017001233.2	6	Reactome: R-HSA-6811434;Reactome: R-HSA-416993;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"Trafficking of GluR2-containing AMPA receptors";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_017005024.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_044250780.1	24	Reactome: R-HSA-432040;KEGG: 04150+2.7.11.11;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-8853659;Reactome: R-HSA-163560;Reactome: R-HSA-4420097;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-163358;Reactome: R-HSA-422356;Reactome: R-HSA-5621575;Reactome: R-HSA-9634600;Reactome: R-HSA-8963896;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-9010642;Reactome: R-HSA-111931;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-392517;Reactome: R-HSA-5610785	"Vasopressin regulates renal water homeostasis via Aquaporins";"mTOR signaling pathway";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"RET signaling";"Triglyceride catabolism";"VEGFA-VEGFR2 Pathway";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"PKA-mediated phosphorylation of key metabolic factors";"Regulation of insulin secretion";"CD209 (DC-SIGN) signaling";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"HDL assembly";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ROBO receptors bind AKAP5";"PKA-mediated phosphorylation of CREB";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Rap1 signalling";"GLI3 is processed to GLI3R by the proteasome"
XP_017012199.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_044248675.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_017001982.2	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_017006758.2	56	Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785	"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome"
XP_017006781.2	2	Reactome: R-HSA-156581;Reactome: R-HSA-72764	"Methylation";"Eukaryotic Translation Termination"
XP_017009978.2	13	KEGG: 04714+2.7.11.1;Reactome: R-HSA-9649948;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-6802946;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802955	"Thermogenesis";"Signaling downstream of RAS mutants";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"MAP2K and MAPK activation";"Signaling by moderate kinase activity BRAF mutants";"Human immunodeficiency virus 1 infection";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_017015708.2	3	Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8939243	"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_017003519.2	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_016994787.2	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_017009335.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016992470.2	3	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_017006962.2	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_017007373.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_017002925.2	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_017000078.2	4	MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-77075	"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_017015128.2	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_016998769.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_017015592.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016994499.2	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_044248577.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016999726.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_017006059.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G-protein activation";"PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_017005004.2	14	MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602	"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_017005372.2	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_017005148.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_017002661.1	27	Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854	"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly"
XP_017000983.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_017000276.2	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_044250776.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016996853.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_017012581.1	9	KEGG: 00020+6.4.1.1;MetaCyc: PWY-6146;KEGG: 00620+6.4.1.1;MetaCyc: PWY-8086;Reactome: R-HSA-70263;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Citrate cycle (TCA cycle)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_044249433.1	13	KEGG: 00511+3.2.1.23;Reactome: R-HSA-2022857;Reactome: R-HSA-4341670;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206308;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.23;Reactome: R-HSA-4085001;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695	"Other glycan degradation";"Keratan sulfate degradation";"Defective NEU1 causes sialidosis";"Galactose metabolism";"MPS IV - Morquio syndrome B";"HS-GAG degradation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Sialic acid metabolism";"Sphingolipid metabolism";"Neutrophil degranulation"
XP_017005394.2	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_017010573.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044251489.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016997599.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_017004120.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_017002125.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016999699.2	4	Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044249784.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017000115.2	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_017014868.2	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_017013627.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017011142.2	12	Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8	"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Synaptic adhesion-like molecules";"Purine metabolism"
XP_016998882.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_044249767.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_017014490.2	10	KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695	"Other glycan degradation";"MPS VII - Sly syndrome";"Galactose metabolism";"HS-GAG degradation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Neutrophil degranulation"
XP_017010308.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_017013334.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_016998771.2	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_044251115.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_017007032.2	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_044251002.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_017001469.2	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_017012688.2	6	Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450513	"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_044249684.1	42	Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-3214842;Reactome: R-HSA-1912408;Reactome: R-HSA-977225;Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-110329;Reactome: R-HSA-5625886;Reactome: R-HSA-9610379;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-69473;Reactome: R-HSA-3214858;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-8939236;Reactome: R-HSA-912446;Reactome: R-HSA-427389;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-5693607;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-8936459;Reactome: R-HSA-171306;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-212300	"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDMs demethylate histones";"Pre-NOTCH Transcription and Translation";"Amyloid fiber formation";"Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HCMV Late Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"G2/M DNA damage checkpoint";"RMTs methylate histone arginines";"DNA methylation";"Estrogen-dependent gene expression";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Meiotic recombination";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Processing of DNA double-strand break ends";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Packaging Of Telomere Ends";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"PRC2 methylates histones and DNA"
XP_017000329.2	7	Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_017011284.2	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_017000210.1	5	MetaCyc: PWY-6692;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-3781	"Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)"
XP_016997052.2	6	Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_044250124.1	11	MetaCyc: PWY-5695;KEGG: 00230+1.17.1.4;Reactome: R-HSA-8851680;MetaCyc: PWY-6999;MetaCyc: PWY-6596;Reactome: R-HSA-74259;MetaCyc: PWY-6607;MetaCyc: PWY-6538;MetaCyc: PWY-6608;MetaCyc: PWY-6606;MetaCyc: PWY-5497	"Inosine 5'-phosphate degradation";"Purine metabolism";"Butyrophilin (BTN) family interactions";"Theophylline degradation";"Adenosine nucleotides degradation I";"Purine catabolism";"Guanosine nucleotides degradation I";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)"
XP_017008778.2	4	Reactome: R-HSA-937039;Reactome: R-HSA-9020702;Reactome: R-HSA-975144;MetaCyc: PWY-7511	"IRAK1 recruits IKK complex";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination"
XP_017000572.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_017013305.2	11	KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00760+3.6.1.9;KEGG: 00240+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7821	"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis"
XP_017000830.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017014917.2	5	Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383	"Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_017012482.1	56	Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-75815	"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Degradation of AXIN";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D"
XP_016995948.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017012491.2	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_017000773.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017011269.2	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016995891.2	13	Reactome: R-HSA-419037;Reactome: R-HSA-3000157;Reactome: R-HSA-216083;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1474244;Reactome: R-HSA-1650814;Reactome: R-HSA-186797;Reactome: R-HSA-2214320;Reactome: R-HSA-8948216;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-2243919	"NCAM1 interactions";"Laminin interactions";"Integrin cell surface interactions";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Extracellular matrix organization";"Collagen biosynthesis and modifying enzymes";"Signaling by PDGF";"Anchoring fibril formation";"Collagen chain trimerization";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Crosslinking of collagen fibrils"
XP_017006531.1	9	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_016993055.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016996287.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-9022692	"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Long-term potentiation";"RAF activation";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity"
XP_017014348.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017002955.2	5	Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619	"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN"
XP_016993094.2	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_016997847.2	3	Reactome: R-HSA-913709;Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"O-linked glycosylation of mucins";"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_016992387.2	2	Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29	"Threonine catabolism";"Glycine, serine and threonine metabolism"
XP_016998858.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_017002824.2	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_016995224.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017012182.2	9	Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842	"Glutathione conjugation";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification II"
XP_044251743.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044250002.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016992501.2	13	MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6370;Reactome: R-HSA-156590;Reactome: R-HSA-196836	"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Ascorbate glutathione cycle";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Ascorbate and aldarate metabolism";"Ascorbate recycling (cytosolic)";"Glutathione conjugation";"Vitamin C (ascorbate) metabolism"
XP_017007237.1	1	Reactome: R-HSA-419771	"Opsins"
XP_017016276.2	11	MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00250+6.3.5.5;KEGG: 00240+2.1.3.2;KEGG: 00250+2.1.3.2;MetaCyc: PWY-7400;MetaCyc: PWY-5686;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5154;MetaCyc: PWY-7791;KEGG: 00240+6.3.5.5	"UMP biosynthesis II";"Pyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis I";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis III";"Pyrimidine metabolism"
XP_016999912.2	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_017011390.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_016993272.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_017013894.2	8	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Signaling by Hippo";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway"
XP_017011702.2	17	Reactome: R-HSA-6798695;KEGG: 00240+2.4.2.1;MetaCyc: PWY-5532;Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-6611;MetaCyc: PWY-5695;MetaCyc: PWY-4202;MetaCyc: PWY-6627;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;MetaCyc: PWY-6620;KEGG: 00230+2.4.2.1;Reactome: R-HSA-74217;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-6609	"Neutrophil degranulation";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Purine catabolism";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage V";"Inosine 5'-phosphate degradation";"Arsenate detoxification I (mammalian)";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Guanine and guanosine salvage";"Purine metabolism";"Purine salvage";"Nicotinate and nicotinamide metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Adenine and adenosine salvage III"
XP_017008313.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_017008156.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017005868.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044249679.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_017002766.2	27	Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-159236	"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_017002427.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_044250647.1	5	MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013	"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III"
XP_044248971.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_017009340.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_017006196.2	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_017000248.2	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_017003118.2	10	Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953	"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation"
XP_017007493.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044251441.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_017007196.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9633012	"Selenocysteine synthesis";"Viral mRNA Translation";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_016995093.2	3	Reactome: R-HSA-8951664;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Neddylation";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_017005067.2	2	Reactome: R-HSA-70171;Reactome: R-HSA-70263	"Glycolysis";"Gluconeogenesis"
XP_016993563.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_044250138.1	56	Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-174084	"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_017012177.2	1	Reactome: R-HSA-428643	"Organic anion transporters"
XP_016993046.2	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_016997138.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044249470.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_044250282.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_017000215.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017005603.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_016993931.2	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_044251526.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016994906.1	11	Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-2151201;Reactome: R-HSA-9627069;Reactome: R-HSA-3299685;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-1268020	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"Transcriptional activation of mitochondrial biogenesis";"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"Mitochondrial protein import"
XP_016997629.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017010690.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017001070.2	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016995776.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_017002377.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_017009390.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016996250.2	17	Reactome: R-HSA-1169091;Reactome: R-HSA-168638;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-937042;Reactome: R-HSA-9645460;Reactome: R-HSA-445989;Reactome: R-HSA-937072;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-975163;Reactome: R-HSA-9014325;Reactome: R-HSA-5357956;Reactome: R-HSA-450302;Reactome: R-HSA-5689880;Reactome: R-HSA-4086398;Reactome: R-HSA-450321	"Activation of NF-kappaB in B cells";"NOD1/2 Signaling Pathway";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"IRAK2 mediated activation of TAK1 complex";"Alpha-protein kinase 1 signaling pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Ub-specific processing proteases";"Ca2+ pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_017006057.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"PLC beta mediated events";"G alpha (i) signalling events"
XP_016997539.2	32	Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-6803529;Reactome: R-HSA-72203;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-167161	"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"FGFR2 alternative splicing";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Estrogen-dependent gene expression";"HIV Transcription Initiation"
XP_016997162.1	21	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7226;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6+2.7.4.3;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7176;MetaCyc: PWY-7219;MetaCyc: PWY-7227;MetaCyc: PWY-7224;MetaCyc: PWY-7222;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7187;MetaCyc: PWY-7205;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis"
XP_016995307.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957	"Neutrophil degranulation";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_017000927.2	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_017004606.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016999667.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016996875.2	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_016992462.2	8	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_017008581.2	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-1834949	"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA"
XP_017008280.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_017008047.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017007775.2	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_017015878.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017007459.1	7	Reactome: R-HSA-3000170;Reactome: R-HSA-6794361;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-373753;Reactome: R-HSA-212676;MetaCyc: PWY-7221	"Syndecan interactions";"Neurexins and neuroligins";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Nephrin family interactions";"Dopamine Neurotransmitter Release Cycle";"Guanosine ribonucleotides de novo biosynthesis"
XP_017010790.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016994117.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017012048.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975956	"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_016998941.2	14	Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-1474228;Reactome: R-HSA-2894862;Reactome: R-HSA-977225;Reactome: R-HSA-9017802;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-6798695	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Amyloid fiber formation";"Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"Neutrophil degranulation"
XP_016993833.2	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_016999688.2	4	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events"
XP_017014008.2	3	MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531	"Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus"
XP_017006967.2	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044251898.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016996726.2	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_017014123.2	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_017005438.2	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_017007010.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_044250023.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044251538.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_017011178.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016992419.1	14	Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167158	"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex"
XP_016998877.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_044250553.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation"
XP_016994040.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_017010764.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044248727.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_044251032.1	6	Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Neutrophil degranulation";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_016998903.2	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_017009833.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017004293.2	7	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_017007173.2	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_017015866.2	2	Reactome: R-HSA-5689880;Reactome: R-HSA-1632852	"Ub-specific processing proteases";"Macroautophagy"
XP_017001481.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-8934903	"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy"
XP_016997907.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044248529.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016999251.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_044250929.1	33	Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-5663220;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531	"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"snRNP Assembly";"RHO GTPases Activate Formins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus"
XP_016994688.2	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_016994659.2	6	Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6798695;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6781827	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Neutrophil degranulation";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_016993652.1	9	Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-380972;Reactome: R-HSA-166208	"Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Amino acids regulate mTORC1";"Neutrophil degranulation";"MAP2K and MAPK activation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling"
XP_017008350.2	4	Reactome: R-HSA-6799198;Reactome: R-HSA-975871;Reactome: R-HSA-975138;Reactome: R-HSA-166058	"Complex I biogenesis";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane"
XP_017015932.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_017008016.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_044250850.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_044251687.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_017014243.2	27	Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-159227	"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA"
XP_017000902.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_044252023.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_017000057.2	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_044249432.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_017004489.2	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_017006324.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_017016071.2	27	Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3301854	"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"snRNP Assembly";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly"
XP_017004413.2	6	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_017011193.2	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016997137.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017015856.2	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_017008424.2	10	Reactome: R-HSA-427413;Reactome: R-HSA-9022538;Reactome: R-HSA-400206;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-8936459;Reactome: R-HSA-9022702	"NoRC negatively regulates rRNA expression";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of lipid metabolism by PPARalpha";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands"
XP_017015204.2	1	Reactome: R-HSA-203615	"eNOS activation"
XP_017001848.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"Translation initiation complex formation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
XP_017014958.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_017011839.2	5	Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-166166	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade"
XP_017014528.2	3	Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361	"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_016998196.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044248593.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044251671.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016993354.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044252021.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_017001075.2	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016998032.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_044251730.1	5	MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6	"Stachyose degradation";"D-galactose detoxification";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism"
XP_016997702.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017005382.2	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_017010019.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_017008266.2	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_017006200.2	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_017006848.1	11	Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-5689880	"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Ub-specific processing proteases"
XP_017000371.2	14	Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-6796648	"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes"
XP_016992591.2	22	Reactome: R-HSA-195253;Reactome: R-HSA-5675221;Reactome: R-HSA-141444;Reactome: R-HSA-5358747;Reactome: R-HSA-432142;Reactome: R-HSA-9648025;Reactome: R-HSA-4641262;Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-5673000;Reactome: R-HSA-2467813;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-2500257;Reactome: R-HSA-389513	"Degradation of beta-catenin by the destruction complex";"Negative regulation of MAPK pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S33 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"EML4 and NUDC in mitotic spindle formation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"RAF activation";"Separation of Sister Chromatids";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling"
XP_016999233.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-6783310;Reactome: R-HSA-110314	"Ub-specific processing proteases";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex"
XP_016994258.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017004184.2	13	KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-5913	"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)"
XP_017013602.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163	"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway"
XP_016994309.2	5	Reactome: R-HSA-209543;Reactome: R-HSA-9020702;Reactome: R-HSA-205043;Reactome: R-HSA-209560;Reactome: R-HSA-5205685	"p75NTR recruits signalling complexes";"Interleukin-1 signaling";"NRIF signals cell death from the nucleus";"NF-kB is activated and signals survival";"Pink/Parkin Mediated Mitophagy"
XP_044249443.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_016997642.2	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044251958.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_044250086.1	1	MetaCyc: PWY-5901	"2,3-dihydroxybenzoate biosynthesis"
XP_044252153.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016993657.2	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_016994050.1	7	KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-5659;MetaCyc: PWY-7456;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-882	"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)"
XP_016993298.2	4	Reactome: R-HSA-8950505;Reactome: R-HSA-1268020;Reactome: R-HSA-3371453;Reactome: R-HSA-8949613	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Mitochondrial protein import";"Regulation of HSF1-mediated heat shock response";"Cristae formation"
XP_016998033.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_044251052.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017001980.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016995055.2	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_016995049.2	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_017006873.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044249241.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_017001862.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_017005492.2	30	Reactome: R-HSA-9604323;Reactome: R-HSA-917937;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-400253;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-69231;Reactome: R-HSA-2565942;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-1170546;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-2122947;Reactome: R-HSA-2644607;Reactome: R-HSA-5684264	"Negative regulation of NOTCH4 signaling";"Iron uptake and transport";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Circadian Clock";"Interleukin-1 signaling";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cyclin D associated events in G1";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Prolactin receptor signaling";"Downstream TCR signaling";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"NOTCH1 Intracellular Domain Regulates Transcription";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation"
XP_016995689.2	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion"
XP_044251393.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_016999647.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_017000924.2	4	KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;Reactome: R-HSA-4549349;KEGG: 00513+2.4.1.257+2.4.1.132	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Various types of N-glycan biosynthesis"
XP_017008329.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_017012710.2	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_017011880.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_017012312.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017003909.2	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_016998972.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016996279.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-6802946;Reactome: R-HSA-936837	"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Long-term potentiation";"HSF1-dependent transactivation";"RAF activation";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases"
XP_016992854.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_044250728.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016999712.1	7	Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-9018519;Reactome: R-HSA-1221632;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214	"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Meiotic synapsis";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins"
XP_016997049.2	12	KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.1.25;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6932;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4	"Selenocompound metabolism";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Sulfite oxidation III";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Selenate reduction";"Sulfate activation for sulfonation";"Purine metabolism"
XP_017012694.2	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_016994794.2	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_044252191.1	10	Reactome: R-HSA-8939243;Reactome: R-HSA-6814122;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-445144	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"Signal transduction by L1"
XP_017000481.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016998589.2	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_017009284.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016999891.2	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_016997023.2	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_017006618.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_017010616.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017012161.2	6	MetaCyc: PWY-5067;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_017006710.2	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017010957.1	24	Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-190840;Reactome: R-HSA-8852276	"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Gap junction assembly";"Kinesins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_016996282.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-438066	"Regulation of MECP2 expression and activity";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Signaling by BRAF and RAF fusions";"RAF activation";"HSF1-dependent transactivation";"Long-term potentiation";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_017010784.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_017009579.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_017013299.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016998325.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017015922.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_017007034.2	10	Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6807505	"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes"
XP_017016215.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044250890.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_044249972.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_017007884.2	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_017012934.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_017005458.2	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_044250104.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_044252174.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_017015427.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016999181.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016995038.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016993224.2	4	Reactome: R-HSA-611105;Reactome: R-HSA-389661;Reactome: R-HSA-77289;Reactome: R-HSA-6799198	"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis"
XP_017014495.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_017008107.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9633012	"Selenocysteine synthesis";"Viral mRNA Translation";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_017001879.2	11	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-383280;Reactome: R-HSA-1368108;Reactome: R-HSA-212436;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-9018519	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Nuclear Receptor transcription pathway";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Generic Transcription Pathway";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Circadian Clock";"Estrogen-dependent gene expression"
XP_017004292.2	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_016992535.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_017001786.1	22	Reactome: R-HSA-70263;KEGG: 00520+5.3.1.9;MetaCyc: PWY-8013;KEGG: 00030+5.3.1.9;Reactome: R-HSA-70171;Reactome: R-HSA-6798695;MetaCyc: PWY-621;MetaCyc: PWY-5384;MetaCyc: PWY-7347;MetaCyc: PWY-5514;MetaCyc: PWY-7238;MetaCyc: PWY-5054;MetaCyc: PWY-3801;MetaCyc: PWY-7385;KEGG: 00500+5.3.1.9;MetaCyc: PWY-5659;MetaCyc: PWY-6992;Reactome: R-HSA-5628897;MetaCyc: PWY-6981;MetaCyc: PWY-622;KEGG: 00010+5.3.1.9;MetaCyc: PWY-6142	"Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Pentose phosphate pathway";"Glycolysis";"Neutrophil degranulation";"Sucrose degradation III (sucrose invertase)";"Sucrose degradation IV (sucrose phosphorylase)";"Sucrose biosynthesis III";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Sucrose biosynthesis II";"D-sorbitol biosynthesis I";"Sucrose degradation II (sucrose synthase)";"1,3-propanediol biosynthesis (engineered)";"Starch and sucrose metabolism";"GDP-mannose biosynthesis";"1,5-anhydrofructose degradation";"TP53 Regulates Metabolic Genes";"Chitin biosynthesis";"Starch biosynthesis";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_044249261.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_017016133.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656	"Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling"
XP_017005716.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_017009903.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017002860.2	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_016997617.2	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_016996478.2	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_017001596.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017007172.2	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_017003225.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition"
XP_017013188.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_017006715.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_016992624.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044249951.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_016993003.2	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_017004525.2	8	KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Activation of RAC1";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis"
XP_044248911.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_017004080.2	10	MetaCyc: PWY-7187;KEGG: 00670+2.1.1.45;Reactome: R-HSA-69205;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7184;MetaCyc: PWY-7199;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-3841	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"One carbon pool by folate";"G1/S-Specific Transcription";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleosides salvage";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Folate transformations II (plants)"
XP_016998811.2	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_044250953.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017007395.2	6	KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00680+5.4.2.11	"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Methane metabolism"
XP_016992457.2	13	KEGG: 00983+2.5.1.18;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6370;Reactome: R-HSA-196836;Reactome: R-HSA-156590;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00980+2.5.1.18;MetaCyc: PWY-2261;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-4061	"Drug metabolism - other enzymes";"Ascorbate and aldarate metabolism";"Ascorbate recycling (cytosolic)";"Vitamin C (ascorbate) metabolism";"Glutathione conjugation";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate glutathione cycle";"Drug metabolism - cytochrome P450";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I"
XP_017004354.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017003780.2	4	Reactome: R-HSA-4549349;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.142;KEGG: 00510+2.4.1.142	"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_044248617.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_017015160.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_016995515.2	6	Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-6804756	"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation"
XP_017005332.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016998189.2	6	KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7433	"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation"
XP_017000213.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017011108.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_017008201.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017012494.2	6	KEGG: 00730+2.7.6.2;MetaCyc: PWY-6907;MetaCyc: PWY-7356;Reactome: R-HSA-196819;MetaCyc: PWY-6908;MetaCyc: PWY-6898	"Thiamine metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage IV (yeast)";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage III"
XP_017012545.1	8	Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-180024	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events"
XP_017001609.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016997514.2	8	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_017006251.2	1	Reactome: R-HSA-2168880	"Scavenging of heme from plasma"
XP_044249955.1	8	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_017003824.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_017014454.2	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_016994934.2	14	MetaCyc: PWY-7254;MetaCyc: PWY-5690;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-561;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-6969;Reactome: R-HSA-611105;KEGG: 00650+1.3.5.1;MetaCyc: PWY-4302	"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Respiratory electron transport";"Butanoate metabolism";"Aerobic respiration III (alternative oxidase pathway)"
XP_017004508.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_017004671.2	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_017001165.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_016993660.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_017005826.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044251919.1	10	Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702;Reactome: R-HSA-8936459;Reactome: R-HSA-9022699;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300	"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates neuronal receptors and channels";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors"
XP_044249643.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_017011794.2	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_016996716.2	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_017012531.2	6	MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis"
XP_017012486.2	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_016997874.1	3	KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367;MetaCyc: PWY-6368	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation"
XP_016997136.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016994058.2	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_016997977.2	5	Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)"
XP_016999321.2	10	Reactome: R-HSA-437239;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Recycling pathway of L1";"Human cytomegalovirus infection";"mTOR signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"RSK activation";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_017002186.2	10	MetaCyc: PWY-4321;KEGG: 00650+2.6.1.19;MetaCyc: PWY-6536;KEGG: 00410+2.6.1.19;KEGG: 00250+2.6.1.19;MetaCyc: PWY-5022;MetaCyc: PWY-6535;MetaCyc: PWY-6537;KEGG: 00640+2.6.1.19;Reactome: R-HSA-916853	"L-glutamate degradation IV";"Butanoate metabolism";"4-aminobutanoate degradation III";"beta-Alanine metabolism";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation V";"4-aminobutanoate degradation I";"4-aminobutanoate degradation II";"Propanoate metabolism";"Degradation of GABA"
XP_017015644.2	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_017009877.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_017009389.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_017003613.2	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_016994433.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017016176.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_017011989.1	1	Reactome: R-HSA-419771	"Opsins"
XP_017012435.2	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_044250514.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017007535.2	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_016998088.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_016997589.2	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_017009435.2	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_017013366.2	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_017000005.2	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_017006868.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_017011200.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016993192.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_017002441.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-6842	"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Glutathione metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II"
XP_017014708.2	6	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2173796;Reactome: R-HSA-5626467;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RHO GTPases activate IQGAPs";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_017007534.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_044250190.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007	"Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy"
XP_017006897.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"Viral mRNA Translation";"Translation initiation complex formation";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
XP_044250898.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_044249339.1	4	Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_044250892.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017005334.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_017009583.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_044249992.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044248854.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_017012185.2	5	Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766;MetaCyc: PWY-7159;MetaCyc: PWY-5531	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)"
XP_017008672.2	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_017005398.2	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_017003078.2	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_017007056.1	5	MetaCyc: PWY-5514;MetaCyc: PWY-6855;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_017010457.2	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_017001559.2	6	Reactome: R-HSA-9029569;Reactome: R-HSA-9022537;Reactome: R-HSA-3214815;Reactome: R-HSA-9022692;Reactome: R-HSA-9609690;Reactome: R-HSA-1989781	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HDACs deacetylate histones";"Regulation of MECP2 expression and activity";"HCMV Early Events";"PPARA activates gene expression"
XP_044251562.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline catabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism"
XP_044250313.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_017006414.2	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_017006944.2	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_017005511.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_044248832.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_017012007.2	7	Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-212300;Reactome: R-HSA-8943724;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690	"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events"
XP_017009127.2	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_016998248.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_016993764.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_017004640.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_017009151.2	4	MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-5737	"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis"
XP_017009304.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_016999045.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_017002858.2	3	Reactome: R-HSA-4086398;Reactome: R-HSA-418457;Reactome: R-HSA-392517	"Ca2+ pathway";"cGMP effects";"Rap1 signalling"
XP_017013174.2	8	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-6804115;Reactome: R-HSA-2565942;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes"
XP_017006488.2	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
XP_017005431.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017010407.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_017011205.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016997061.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_017001894.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_017007061.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016999490.2	13	Reactome: R-HSA-445989;Reactome: R-HSA-450302;Reactome: R-HSA-9645460;Reactome: R-HSA-5357956;Reactome: R-HSA-450321;Reactome: R-HSA-937072;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-975163;Reactome: R-HSA-9014325;Reactome: R-HSA-937042;Reactome: R-HSA-9020702;Reactome: R-HSA-168638	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"activated TAK1 mediates p38 MAPK activation";"Alpha-protein kinase 1 signaling pathway";"TNFR1-induced NFkappaB signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK2 mediated activation of TAK1 complex";"Interleukin-1 signaling";"NOD1/2 Signaling Pathway"
XP_044251224.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_017005920.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044252175.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"HCMV Early Events"
XP_016992677.2	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_017011296.2	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_016994800.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Neutrophil degranulation";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_016995039.1	6	Reactome: R-HSA-983168;Reactome: R-HSA-8863795;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-2173788	"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2 signaling";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Protein ubiquitination";"Downregulation of TGF-beta receptor signaling"
XP_017010878.2	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_017010889.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168	"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016998696.2	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_016996284.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-438066	"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"RAF activation";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_044248493.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_017003949.2	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_017004193.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017008691.2	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_017009947.2	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_016993099.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-4615885	"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"SUMOylation of DNA replication proteins"
XP_017003573.1	11	Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-3371497;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes"
XP_016993918.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_017009366.2	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016995127.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017004555.2	5	Reactome: R-HSA-8937144;Reactome: R-HSA-1989781;Reactome: R-HSA-211945;Reactome: R-HSA-211976;Reactome: R-HSA-211981	"Aryl hydrocarbon receptor signalling";"PPARA activates gene expression";"Phase I - Functionalization of compounds";"Endogenous sterols";"Xenobiotics"
XP_017004622.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_017014081.1	5	KEGG: 00561+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-6798695;KEGG: 00073+2.3.1.20;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Acyl chain remodeling of DAG and TAG";"Neutrophil degranulation";"Cutin, suberine and wax biosynthesis";"Triglyceride biosynthesis"
XP_044250596.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_016994331.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation"
XP_017014006.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017006214.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_044250261.1	29	MetaCyc: PWY-6313;MetaCyc: PWY-7111;MetaCyc: PWY-5078;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5486;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5082;KEGG: 00980+1.1.1.1;KEGG: 00982+1.1.1.1;MetaCyc: PWY-5751;MetaCyc: PWY-6871;KEGG: 00625+1.1.1.1;KEGG: 00010+1.1.1.1;KEGG: 00592+1.1.1.1;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5057;MetaCyc: PWY-7013;MetaCyc: PWY-6587;MetaCyc: PWY-6333;KEGG: 00260+1.1.1.1;MetaCyc: PWY-6342;MetaCyc: PWY-5480;MetaCyc: PWY-5079;MetaCyc: PWY-7396;MetaCyc: PWY-5076;MetaCyc: PWY-6802;KEGG: 00071+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-3162	"Serotonin degradation";"Pyruvate fermentation to isobutanol (engineered)";"L-isoleucine degradation II";"Naphthalene degradation";"Pyruvate fermentation to ethanol II";"Retinol metabolism";"L-methionine degradation III";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Phenylethanol biosynthesis";"3-methylbutanol biosynthesis (engineered)";"Chloroalkane and chloroalkene degradation";"Glycolysis / Gluconeogenesis";"alpha-Linolenic acid metabolism";"Tyrosine metabolism";"L-valine degradation II";"(S)-propane-1,2-diol degradation";"Pyruvate fermentation to ethanol III";"Acetaldehyde biosynthesis I";"Glycine, serine and threonine metabolism";"Noradrenaline and adrenaline degradation";"Pyruvate fermentation to ethanol I";"L-phenylalanine degradation III";"Butanol and isobutanol biosynthesis (engineered)";"L-leucine degradation III";"Salidroside biosynthesis";"Fatty acid degradation";"Chitin degradation to ethanol";"L-tryptophan degradation V (side chain pathway)"
XP_044251681.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975957	"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_017013158.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_017009286.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044250105.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_044248613.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_017007254.2	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_017012580.2	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_017001374.2	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_016993044.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_044249185.1	8	Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5689880;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Ub-specific processing proteases";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_017004454.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex"
XP_044250177.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Protein ubiquitination";"Fanconi Anemia Pathway"
XP_016995941.2	13	MetaCyc: PWY-7184;MetaCyc: PWY-7821;KEGG: 00740+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00230+3.6.1.66;KEGG: 00230+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7187;KEGG: 00760+3.6.1.9;Reactome: R-HSA-74259;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis";"Riboflavin metabolism";"Pantothenate and CoA biosynthesis";"Starch and sucrose metabolism";"Purine metabolism";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Nicotinate and nicotinamide metabolism";"Purine catabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_017007006.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016996283.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692	"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Long-term potentiation";"HSF1-dependent transactivation";"RAF activation";"Signaling by BRAF and RAF fusions";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Regulation of MECP2 expression and activity"
XP_016993689.1	34	Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-9639288;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-5663220;Reactome: R-HSA-5619107	"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"Amino acids regulate mTORC1";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"RHO GTPases Activate Formins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
XP_017004152.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_017007767.2	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_017008529.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_017012529.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_016999640.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_017015048.2	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_017007680.2	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_017002872.2	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_017011535.2	2	Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17	"Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions"
XP_017014453.2	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_016997484.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016998840.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017006717.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_017004809.1	14	Reactome: R-HSA-141444;Reactome: R-HSA-9634638;Reactome: R-HSA-5687128;Reactome: R-HSA-3769402;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-450520;Reactome: R-HSA-68877;Reactome: R-HSA-69273;Reactome: R-HSA-2467813;Reactome: R-HSA-2173788;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"MAPK6/MAPK4 signaling";"Deactivation of the beta-catenin transactivating complex";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"HuR (ELAVL1) binds and stabilizes mRNA";"Mitotic Prometaphase";"Cyclin A/B1/B2 associated events during G2/M transition";"Separation of Sister Chromatids";"Downregulation of TGF-beta receptor signaling";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_017005569.2	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_017015192.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_017011696.2	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_017012445.2	16	Reactome: R-HSA-9664565;Reactome: R-HSA-6785631;Reactome: R-HSA-1227986;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-1963640;Reactome: R-HSA-1250196;Reactome: R-HSA-1250342;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-1236394;Reactome: R-HSA-1257604;Reactome: R-HSA-1250347;Reactome: R-HSA-1963642;Reactome: R-HSA-5673001;Reactome: R-HSA-1251985	"Signaling by ERBB2 KD Mutants";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"GRB2 events in ERBB2 signaling";"SHC1 events in ERBB2 signaling";"PI3K events in ERBB4 signaling";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB4";"PIP3 activates AKT signaling";"SHC1 events in ERBB4 signaling";"PI3K events in ERBB2 signaling";"RAF/MAP kinase cascade";"Nuclear signaling by ERBB4"
XP_017003808.2	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_017012002.2	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_017000557.2	8	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Signaling by Hippo";"PI3K-Akt signaling pathway"
XP_016994792.2	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_017010792.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_017002814.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044251779.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_017007774.2	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
XP_017003320.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_044252169.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"HCMV Early Events"
XP_017009041.2	57	Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-195253	"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex"
XP_017009067.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016993562.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016994801.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_017001738.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017000777.1	9	Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-5696394;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-110314;Reactome: R-HSA-6781823	"Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex"
XP_017001149.1	18	Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167243	"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery"
XP_017010227.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016997369.2	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_044252070.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;MetaCyc: PWY-7511	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"Protein ubiquitination"
XP_017015611.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-159227	"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA"
XP_017000274.2	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_017001115.2	10	KEGG: 05165+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 05170+2.7.1.153;KEGG: 00562+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 04151+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05163+2.7.1.153	"Human papillomavirus infection";"Synthesis of PIPs at the plasma membrane";"Human immunodeficiency virus 1 infection";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human cytomegalovirus infection"
XP_017009332.2	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_017009111.2	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_044252156.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_017011165.2	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_017001006.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016996236.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_017008091.2	15	Reactome: R-HSA-5685939;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-69473	"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"G2/M DNA damage checkpoint"
XP_017004131.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_017009454.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090	"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures"
XP_017011749.2	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_016999104.1	6	MetaCyc: PWY-8004;KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484;MetaCyc: PWY-1622	"Entner-Doudoroff pathway I";"Methane metabolism";"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)"
XP_017012943.2	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_044250121.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_044252014.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_044251106.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_016995215.2	11	Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-163359	"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Glucagon signaling in metabolic regulation"
XP_044250612.1	8	Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-163615	"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation"
XP_017004905.2	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_017014255.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016999463.2	7	Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69202	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition"
XP_044251550.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016998034.2	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_044249485.1	42	Reactome: R-HSA-912446;Reactome: R-HSA-73772;Reactome: R-HSA-427389;Reactome: R-HSA-73728;Reactome: R-HSA-5693607;Reactome: R-HSA-3214841;Reactome: R-HSA-8939236;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-3214847;Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-171306;Reactome: R-HSA-8936459;Reactome: R-HSA-9616222;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-2559580;Reactome: R-HSA-110329;Reactome: R-HSA-9610379;Reactome: R-HSA-5625886;Reactome: R-HSA-2559586;Reactome: R-HSA-977225;Reactome: R-HSA-1221632;Reactome: R-HSA-5617472;Reactome: R-HSA-3214842;Reactome: R-HSA-1912408;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-201722;Reactome: R-HSA-3214815;Reactome: R-HSA-3214858;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-110328;Reactome: R-HSA-2299718;Reactome: R-HSA-5250924	"Meiotic recombination";"RNA Polymerase I Promoter Escape";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Opening";"Processing of DNA double-strand break ends";"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"DNA methylation";"HATs acetylate histones";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"Packaging Of Telomere Ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation of granulopoiesis";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Oxidative Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"HCMV Late Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA Damage/Telomere Stress Induced Senescence";"Amyloid fiber formation";"Meiotic synapsis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HDMs demethylate histones";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex";"HDACs deacetylate histones";"RMTs methylate histone arginines";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Condensation of Prophase Chromosomes";"B-WICH complex positively regulates rRNA expression"
XP_017004209.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017007669.2	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_016997361.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017008880.2	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_017008344.2	7	MetaCyc: PWY-6352;KEGG: 04070+2.7.1.67;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660499;MetaCyc: PWY-6351;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516	"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane"
XP_017003817.1	57	Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway"
XP_016999360.2	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_017000149.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017007668.2	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_017008496.2	27	Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-3371453	"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response"
XP_017005609.1	56	Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-69481	"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Separation of Sister Chromatids";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"G2/M Checkpoints"
XP_017011245.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_017000116.2	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_016997063.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016993074.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_017011548.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_017013565.2	5	Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-532668;Reactome: R-HSA-8957275;Reactome: R-HSA-879415	"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling"
XP_017009793.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017009966.2	2	KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_017004611.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_017008094.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_017000304.1	8	MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7115	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_017000268.2	10	KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-5030;MetaCyc: PWY-6613;MetaCyc: PWY-2201;MetaCyc: PWY-1722;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497	"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Folate transformations II (plants)";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)"
XP_016996991.2	18	KEGG: 00270+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-7115;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5392	"Cysteine and methionine metabolism";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methane metabolism";"Partial TCA cycle (obligate autotrophs)";"Glyoxylate and dicarboxylate metabolism";"Reductive TCA cycle II"
XP_017001954.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_016996627.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_017009445.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216	"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization"
XP_017011103.2	4	KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451;MetaCyc: PWY-5189;MetaCyc: PWY-5188	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_016995079.2	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_017010991.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_044251160.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_044248912.1	7	Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105	"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"O-linked glycosylation"
XP_016995299.2	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_017004559.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017005341.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_017000303.2	7	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-380972	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTOR signalling";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_017011023.2	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_016999847.1	5	KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism"
XP_016999967.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044250930.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044250954.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_017008472.2	6	MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism"
XP_017005248.2	7	Reactome: R-HSA-1442490;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826	"Collagen degradation";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_017014010.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-68827	"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex"
XP_016996445.2	15	Reactome: R-HSA-9665244;Reactome: R-HSA-9665233;Reactome: R-HSA-9665251;Reactome: R-HSA-1227986;Reactome: R-HSA-5637810;Reactome: R-HSA-9664565;Reactome: R-HSA-9665249;Reactome: R-HSA-9665250;Reactome: R-HSA-9652282;Reactome: R-HSA-9665245;Reactome: R-HSA-9665246;Reactome: R-HSA-1236382;Reactome: R-HSA-9634285;Reactome: R-HSA-9665247;Reactome: R-HSA-8863795	"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to lapatinib";"Signaling by ERBB2";"Constitutive Signaling by EGFRvIII";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to AEE788";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to neratinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to osimertinib";"Downregulation of ERBB2 signaling"
XP_016994731.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_017007588.1	7	Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-8950505;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-390471	"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis"
XP_017003528.2	8	MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826;Reactome: R-HSA-74217;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-7179	"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine metabolism";"Surfactant metabolism";"Purine salvage";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I"
XP_017002253.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016997364.2	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_016992341.2	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_017007251.2	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016993482.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044251102.1	3	Reactome: R-HSA-418457;Reactome: R-HSA-4086398;Reactome: R-HSA-392517	"cGMP effects";"Ca2+ pathway";"Rap1 signalling"
XP_016997296.2	5	Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-9649948	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Negative regulation of MAPK pathway";"Signaling downstream of RAS mutants"
XP_017008707.2	14	MetaCyc: PWY-8041;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5080	"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I"
XP_017011198.2	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_017005543.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_044251021.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016999458.2	6	Reactome: R-HSA-76005;Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900	"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4"
XP_017014309.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_044249575.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Translation initiation complex formation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016993370.1	14	Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-1632852;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5620924;Reactome: R-HSA-9646399	"MHC class II antigen presentation";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Macroautophagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Intraflagellar transport";"Aggrephagy"
XP_017015078.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_017009173.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016992584.2	22	Reactome: R-HSA-6811558;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-2467813;Reactome: R-HSA-5673000;Reactome: R-HSA-2500257;Reactome: R-HSA-389513;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-5675221;Reactome: R-HSA-432142;Reactome: R-HSA-9648025;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"RAF activation";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"Negative regulation of MAPK pathway";"Platelet sensitization by LDL";"EML4 and NUDC in mitotic spindle formation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex"
XP_017012225.2	12	MetaCyc: PWY-5871;MetaCyc: PWY-5856;MetaCyc: PWY-5870;MetaCyc: PWY-5855;KEGG: 00130+1.14.99.60;Reactome: R-HSA-2142789;MetaCyc: PWY-7233;MetaCyc: PWY-7230;MetaCyc: PWY-5857;MetaCyc: PWY-6708;MetaCyc: PWY-5873;MetaCyc: PWY-5872	"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)"
XP_016995986.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016997947.2	2	Reactome: R-HSA-5601884;Reactome: R-HSA-1221632	"PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis"
XP_016993225.2	4	Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-77289	"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation"
XP_017011195.2	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016999735.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_017004604.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016994825.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016994816.2	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13	"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Glutathione metabolism"
XP_017009011.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_016997721.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017001467.2	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_016997356.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016995143.2	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_017012744.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_017003399.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_017003323.2	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_017005786.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_016995623.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044249483.1	42	Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-5578749;Reactome: R-HSA-8939236;Reactome: R-HSA-3214841;Reactome: R-HSA-5693607;Reactome: R-HSA-73728;Reactome: R-HSA-912446;Reactome: R-HSA-427389;Reactome: R-HSA-73772;Reactome: R-HSA-9616222;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-171306;Reactome: R-HSA-8936459;Reactome: R-HSA-9609690;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-212300;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-1912408;Reactome: R-HSA-3214842;Reactome: R-HSA-5617472;Reactome: R-HSA-9610379;Reactome: R-HSA-110329;Reactome: R-HSA-5625886;Reactome: R-HSA-977225;Reactome: R-HSA-2559586;Reactome: R-HSA-1221632;Reactome: R-HSA-2559580;Reactome: R-HSA-2299718;Reactome: R-HSA-5250924;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-3214858;Reactome: R-HSA-69473;Reactome: R-HSA-201722;Reactome: R-HSA-3214815	"HATs acetylate histones";"Estrogen-dependent gene expression";"DNA methylation";"Transcriptional regulation by small RNAs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PKMTs methylate histone lysines";"Processing of DNA double-strand break ends";"RNA Polymerase I Promoter Opening";"Meiotic recombination";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape";"Transcriptional regulation of granulopoiesis";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Packaging Of Telomere Ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Early Events";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Pre-NOTCH Transcription and Translation";"HDMs demethylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Late Events";"Cleavage of the damaged pyrimidine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Amyloid fiber formation";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic synapsis";"Oxidative Stress Induced Senescence";"Condensation of Prophase Chromosomes";"B-WICH complex positively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"RMTs methylate histone arginines";"G2/M DNA damage checkpoint";"Formation of the beta-catenin:TCF transactivating complex";"HDACs deacetylate histones"
XP_017004409.2	3	MetaCyc: PWY-7511;Reactome: R-HSA-6807505;Reactome: R-HSA-983168	"Protein ubiquitination";"RNA polymerase II transcribes snRNA genes";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016994703.2	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_016993411.2	5	Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661;MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88	"Proline catabolism";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation";"Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism"
XP_016998894.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016999890.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016997050.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016997259.2	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_017010781.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_017002934.2	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_017015479.2	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_017011699.2	17	MetaCyc: PWY-4202;MetaCyc: PWY-5695;MetaCyc: PWY-7179-1;MetaCyc: PWY-6627;KEGG: 00240+2.4.2.1;Reactome: R-HSA-6798695;Reactome: R-HSA-74259;MetaCyc: PWY-5532;MetaCyc: PWY-6611;MetaCyc: PWY-6608;Reactome: R-HSA-74217;MetaCyc: PWY-6609;MetaCyc: PWY-6644;KEGG: 00760+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-6620;KEGG: 00230+2.4.2.1	"Arsenate detoxification I (mammalian)";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation II";"Salinosporamide A biosynthesis";"Pyrimidine metabolism";"Neutrophil degranulation";"Purine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage V";"Guanosine nucleotides degradation III";"Purine salvage";"Adenine and adenosine salvage III";"Fluoroacetate and fluorothreonine biosynthesis";"Nicotinate and nicotinamide metabolism";"Purine deoxyribonucleosides degradation I";"Guanine and guanosine salvage";"Purine metabolism"
XP_017009982.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-936837	"Cation-coupled Chloride cotransporters";"Ion transport by P-type ATPases"
XP_016999139.2	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_016998965.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016993439.2	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_016997606.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016995852.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_017007598.2	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016995379.2	4	Reactome: R-HSA-189451;MetaCyc: PWY-5189;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75	"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism"
XP_017013675.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044249405.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_044252189.1	10	Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903	"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy"
XP_044249773.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_017013344.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_016997107.2	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_017001101.2	2	KEGG: 00970+6.1.1.9;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_017004009.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_017011434.2	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_016999914.2	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_017003708.2	5	KEGG: 00900+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560	"Terpenoid backbone biosynthesis";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Methylerythritol phosphate pathway II"
XP_044251159.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828	"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Clathrin-mediated endocytosis"
XP_016993402.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044248746.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017013604.2	3	Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-4419969	"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina"
XP_017015096.1	16	Reactome: R-HSA-8936459;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence"
XP_017016203.1	4	Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656	"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry"
XP_017006681.2	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_017010579.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_017005658.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_017000004.2	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_016992548.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044251259.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_017006679.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_044251381.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_017002143.2	3	MetaCyc: PWY-1269;KEGG: 00540+2.7.7.38;Reactome: R-HSA-4085001	"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Lipopolysaccharide biosynthesis";"Sialic acid metabolism"
XP_017001288.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016994743.2	24	Reactome: R-HSA-432040;Reactome: R-HSA-8964315;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-4086398;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-418594;Reactome: R-HSA-420092;Reactome: R-HSA-9009391;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-418217;Reactome: R-HSA-163359;Reactome: R-HSA-392170;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-418555;Reactome: R-HSA-416482;Reactome: R-HSA-418597;Reactome: R-HSA-202040;Reactome: R-HSA-456926	"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through BTK";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"Ca2+ pathway";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (i) signalling events";"Glucagon-type ligand receptors";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 12";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (s) signalling events";"G alpha (12/13) signalling events";"G alpha (z) signalling events";"G-protein activation";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_017005757.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_017015933.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_017006215.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_017004926.1	16	Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-6796648	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes"
XP_017005150.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016999909.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602	"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_017002422.1	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_016994878.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017001905.2	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_017014970.2	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_017010864.2	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_016993659.2	5	Reactome: R-HSA-381426;Reactome: R-HSA-532668;Reactome: R-HSA-901042;Reactome: R-HSA-8957275;Reactome: R-HSA-879415	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle";"Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling"
XP_016998813.2	29	Reactome: R-HSA-3371453;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-6804756;Reactome: R-HSA-6803207;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-6804760;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-349425;Reactome: R-HSA-6803204;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-6796648;Reactome: R-HSA-5693568;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69541;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693548;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69473;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693571	"Regulation of HSF1-mediated heat shock response";"Thermogenesis";"Relaxin signaling pathway";"Regulation of TP53 Degradation";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Methylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"Autodegradation of the E3 ubiquitin ligase COP1";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Holliday Junction Intermediates";"mTOR signaling pathway";"Human cytomegalovirus infection";"Stabilization of p53";"PI3K-Akt signaling pathway";"Sensing of DNA Double Strand Breaks";"Human papillomavirus infection";"G2/M DNA damage checkpoint";"Human immunodeficiency virus 1 infection";"Nonhomologous End-Joining (NHEJ)"
XP_016998777.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_044252020.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_016999876.2	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_017003605.2	10	Reactome: R-HSA-380972;Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-200425;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483	"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Carnitine metabolism";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs"
XP_044250771.1	7	Reactome: R-HSA-203927;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-1655829	"MicroRNA (miRNA) biogenesis";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_016993404.2	5	Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;MetaCyc: PWY-6853;Reactome: R-HSA-389661;KEGG: 00250+1.2.1.88	"Proline catabolism";"Arginine and proline metabolism";"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation";"Alanine, aspartate and glutamate metabolism"
XP_017008683.2	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_016999047.2	6	KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6124;MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123	"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I"
XP_016997840.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044249245.1	11	Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-2022928;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475	"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"HS-GAG biosynthesis";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_016996475.2	4	Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016996139.2	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_017014463.2	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_016999120.2	18	KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;MetaCyc: PWY-8051;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482801	"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PS"
XP_017015629.2	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_044249154.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_017014877.1	6	Reactome: R-HSA-6781827;MetaCyc: PWY-7511;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Protein ubiquitination";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_044252025.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_016998530.2	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_044249891.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_017007107.2	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_017013140.2	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_016995314.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_044250838.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_017011157.2	8	KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-438066	"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_016999197.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016993115.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017005502.1	12	KEGG: 00520+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00500+2.7.7.9;KEGG: 00040+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-7343;MetaCyc: PWY-7238;MetaCyc: PWY-7817;Reactome: R-HSA-173599;KEGG: 00052+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00561+2.7.7.9	"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Starch and sucrose metabolism";"Pentose and glucuronate interconversions";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Formation of the active cofactor, UDP-glucuronate";"Galactose metabolism";"Sucrose degradation II (sucrose synthase)";"Glycerolipid metabolism"
XP_017000214.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017004455.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex"
XP_044250841.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016998914.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_016993330.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_044250736.1	10	Reactome: R-HSA-5689880;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-9636383;Reactome: R-HSA-917729;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-9635644;Reactome: R-HSA-432720	"Ub-specific processing proteases";"Clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"Inhibition of membrane repair";"Lysosome Vesicle Biogenesis"
XP_017014714.1	9	MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-5744;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-7117	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_017014883.1	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_016996542.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_017007604.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_017004167.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016992855.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_017008238.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044251265.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_017003192.2	9	Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167162	"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape"
XP_017013862.2	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_016998883.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_017008084.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016992605.1	19	KEGG: 00020+1.1.1.37;MetaCyc: PWY-7383;Reactome: R-HSA-70263;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00620+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-1622;Reactome: R-HSA-71403;MetaCyc: PWY-7115;MetaCyc: PWY-561;MetaCyc: PWY-8086;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-5913;KEGG: 00630+1.1.1.37;KEGG: 00680+1.1.1.37	"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Cysteine and methionine metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Formaldehyde assimilation I (serine pathway)";"Citric acid cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation in photosynthetic organisms";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism"
XP_044249901.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_017005294.2	4	MetaCyc: PWY-7887;Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12	"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_017012729.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017002059.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044249837.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_017003317.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_017011782.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016996374.1	7	MetaCyc: PWY-7805;MetaCyc: PWY-6610;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-6605;MetaCyc: PWY-7807;KEGG: 00230+2.4.2.7	"(aminomethyl)phosphonate degradation";"Adenine salvage";"Neutrophil degranulation";"Purine salvage";"Adenine and adenosine salvage II";"Glyphosate degradation III";"Purine metabolism"
XP_017010839.2	7	KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Myo-inositol biosynthesis";"Streptomycin biosynthesis"
XP_044250516.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_044251196.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016996869.2	13	KEGG: 00511+3.2.1.23;Reactome: R-HSA-2022857;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;Reactome: R-HSA-4085001;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096;MetaCyc: PWY-6807;Reactome: R-HSA-1660662;KEGG: 00052+3.2.1.23;Reactome: R-HSA-4341670;Reactome: R-HSA-2206308	"Other glycan degradation";"Keratan sulfate degradation";"Sphingolipid metabolism";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Sialic acid metabolism";"Glycosaminoglycan degradation";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid metabolism";"Galactose metabolism";"Defective NEU1 causes sialidosis";"MPS IV - Morquio syndrome B"
XP_017002566.2	5	Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_017014465.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016995905.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_017001168.2	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-7268	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_017008780.1	10	Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-674695	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events"
XP_017005912.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044252028.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_017012538.2	6	Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule"
XP_017013442.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels"
XP_017002049.2	7	MetaCyc: PWY-7886;MetaCyc: PWY-7818;Reactome: R-HSA-1483191;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-3385;MetaCyc: PWY-7782;Reactome: R-HSA-1483213	"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PC";"Glycerophospholipid metabolism";"Choline biosynthesis I";"Plasmalogen biosynthesis";"Synthesis of PE"
XP_016996992.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017004810.2	3	Reactome: R-HSA-2206282;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50	"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation";"Glycosaminoglycan degradation"
XP_016994989.1	5	Reactome: R-HSA-936440;Reactome: R-HSA-1169408;Reactome: R-HSA-5668599;Reactome: R-HSA-6804756;Reactome: R-HSA-6811555	"Negative regulators of DDX58/IFIH1 signaling";"ISG15 antiviral mechanism";"RHO GTPases Activate NADPH Oxidases";"Regulation of TP53 Activity through Phosphorylation";"PI5P Regulates TP53 Acetylation"
XP_016994474.2	9	Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332	"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1"
XP_017012339.2	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_017005304.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_017011686.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016992623.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_017004507.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_017015095.1	16	Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398	"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Ca2+ pathway"
XP_044249515.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017009660.2	3	KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2;Reactome: R-HSA-8963684	"Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism"
XP_017012340.2	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_044251980.1	13	MetaCyc: PWY-6370;Reactome: R-HSA-196836;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;KEGG: 00053+1.8.5.1;MetaCyc: PWY-2261;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18+1.8.5.1	"Ascorbate recycling (cytosolic)";"Vitamin C (ascorbate) metabolism";"Glutathione conjugation";"Drug metabolism - other enzymes";"Ascorbate and aldarate metabolism";"Ascorbate glutathione cycle";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione metabolism"
XP_016996415.1	12	Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167200	"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_044251430.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_017015897.2	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_016992329.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016997257.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017010728.2	24	KEGG: 04151+2.7.11.1;Reactome: R-HSA-1257604;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-114604;Reactome: R-HSA-444257;Reactome: R-HSA-165158;Reactome: R-HSA-392451;Reactome: R-HSA-2730905;Reactome: R-HSA-389357;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-354192;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;Reactome: R-HSA-6804757;Reactome: R-HSA-202424;Reactome: R-HSA-5625740;Reactome: R-HSA-2871837	"PI3K-Akt signaling pathway";"PIP3 activates AKT signaling";"Human papillomavirus infection";"VEGFR2 mediated vascular permeability";"GPVI-mediated activation cascade";"RSK activation";"Activation of AKT2";"G beta:gamma signalling through PI3Kgamma";"Role of LAT2/NTAL/LAB on calcium mobilization";"CD28 dependent PI3K/Akt signaling";"Human immunodeficiency virus 1 infection";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Human cytomegalovirus infection";"Integrin signaling";"Thermogenesis";"Relaxin signaling pathway";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"Regulation of TP53 Degradation";"Downstream TCR signaling";"RHO GTPases activate PKNs";"FCERI mediated NF-kB activation"
XP_017014084.1	17	Reactome: R-HSA-5693616;Reactome: R-HSA-8953750;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1433557;Reactome: R-HSA-176187;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69601;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-6796648;Reactome: R-HSA-75035;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Relaxin signaling pathway";"Signaling by SCF-KIT";"Activation of ATR in response to replication stress";"Human immunodeficiency virus 1 infection";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of DNA Repair Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_016995543.2	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_017006810.1	12	Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-9017802;Reactome: R-HSA-977225	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"Noncanonical activation of NOTCH3";"Amyloid fiber formation"
XP_017003644.1	13	Reactome: R-HSA-5099900;Reactome: R-HSA-8866427;Reactome: R-HSA-416993;Reactome: R-HSA-437239;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-5140745;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-167590;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-182218	"WNT5A-dependent internalization of FZD4";"VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors";"Recycling pathway of L1";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD4 Down-regulation";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation"
XP_017015957.1	10	Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243	"Signal transduction by L1";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_017004250.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_016996089.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_017002026.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_017014951.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_017008739.1	56	Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-4641258	"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL"
XP_017011137.2	12	Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932	"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Synaptic adhesion-like molecules"
XP_016997694.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823	"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation"
XP_017006062.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_017004258.2	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
XP_044249331.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_017008265.2	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_017011192.2	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_017010601.2	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_017004593.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_044250055.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_044249752.1	3	MetaCyc: PWY-4041;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9	"Gamma-glutamyl cycle";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_016995156.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_017011145.2	12	Reactome: R-HSA-451308;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324	"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Synaptic adhesion-like molecules";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_016995685.2	6	MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_017003942.2	9	MetaCyc: PWY-7117;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism"
XP_017010426.2	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_016994744.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_017007976.2	3	Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7888	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)"
XP_017005022.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_017015664.1	6	MetaCyc: PWY-6854;Reactome: R-HSA-2151201;Reactome: R-HSA-8862803;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-8950505	"Ethylene biosynthesis III (microbes)";"Transcriptional activation of mitochondrial biogenesis";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_017000555.2	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_017016150.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016998822.1	5	Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_017015970.2	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_017003015.2	3	Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007	"Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy"
XP_017012955.2	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_016992857.2	13	MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52	"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_016996868.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_017011556.2	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_044251762.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017006066.2	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_017009876.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_017001863.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_017010432.2	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_016994206.2	26	Reactome: R-HSA-110312;Reactome: R-HSA-174417;Reactome: R-HSA-6782135;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-69205;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-69183;Reactome: R-HSA-5656169;Reactome: R-HSA-4615885;Reactome: R-HSA-8866654;Reactome: R-HSA-174437;Reactome: R-HSA-6804114;Reactome: R-HSA-174414;Reactome: R-HSA-1362277;Reactome: R-HSA-6782210;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-110320	"Translesion synthesis by REV1";"Telomere C-strand (Lagging Strand) Synthesis";"Dual incision in TC-NER";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"G1/S-Specific Transcription";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Processive synthesis on the lagging strand";"Termination of translesion DNA synthesis";"SUMOylation of DNA replication proteins";"E3 ubiquitin ligases ubiquitinate target proteins";"Removal of the Flap Intermediate from the C-strand";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Processive synthesis on the C-strand of the telomere";"Transcription of E2F targets under negative control by DREAM complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH"
XP_016999653.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_017003019.2	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_044249800.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017014869.2	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_017015281.2	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_017005211.2	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_017000874.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044248461.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_017012797.1	8	KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-983712;KEGG: 00190+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Photosynthesis";"ATP biosynthesis";"Ion channel transport";"Oxidative phosphorylation";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_017004731.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044249747.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016998931.2	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_044251434.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_016993663.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017013567.2	5	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-532668;Reactome: R-HSA-901042;Reactome: R-HSA-879415	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling"
XP_017004420.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation"
XP_017001393.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_017001140.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_016998218.1	7	KEGG: 00330+3.5.3.1;MetaCyc: PWY-4984;MetaCyc: PWY-6922;MetaCyc: PWY-31;Reactome: R-HSA-70635;MetaCyc: PWY-46;KEGG: 00220+3.5.3.1	"Arginine and proline metabolism";"Urea cycle";"L-Ndelta-acetylornithine biosynthesis";"Canavanine degradation";"Urea cycle";"Putrescine biosynthesis III";"Arginine biosynthesis"
XP_017006971.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044250392.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016997399.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_017010437.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_044250170.1	3	Reactome: R-HSA-8953750;Reactome: R-HSA-427389;Reactome: R-HSA-73772	"Transcriptional Regulation by E2F6";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape"
XP_044248998.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016999506.1	6	Reactome: R-HSA-76005;Reactome: R-HSA-418597;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-5099900	"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4"
XP_044251780.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_017001917.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_017005731.2	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_017011727.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_017001881.2	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_017000564.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_016995518.2	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_017001397.2	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_017000628.2	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_017001725.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_017015097.1	16	Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897	"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes"
XP_044249313.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_017007035.2	4	MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes"
XP_016998200.2	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016995937.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_017009331.2	2	Reactome: R-HSA-446193;Reactome: R-HSA-4570571	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)"
XP_017004138.2	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_016999370.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_017013006.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_017007683.1	12	KEGG: 00030+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1042;Reactome: R-HSA-70263;MetaCyc: PWY-1861;MetaCyc: PWY-7385;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00010+4.1.2.13	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Glycolysis";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis"
XP_017004535.1	4	MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581	"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation"
XP_017014349.2	6	Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;MetaCyc: PWY-6922	"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis"
XP_017015722.2	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
XP_017009348.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017008326.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044249139.1	8	Reactome: R-HSA-9627069;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-6798695;Reactome: R-HSA-6803207;Reactome: R-HSA-111458;Reactome: R-HSA-111463	"Regulation of the apoptosome activity";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs"
XP_017009448.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216	"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization"
XP_016993084.2	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_017005442.2	3	MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700	"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)"
XP_017002631.2	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_016992340.2	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_017008335.2	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_017007868.2	11	Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-2022928	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"HS-GAG biosynthesis"
XP_017007577.2	9	Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-69205;Reactome: R-HSA-113501	"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"DNA replication initiation";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_017005672.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_017014014.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_017008900.2	27	Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-168325	"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis"
XP_017005411.2	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_016999711.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation"
XP_044250192.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_017011356.2	7	MetaCyc: PWY-7176;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.14	"UTP and CTP de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes"
XP_017000989.2	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_017014851.1	4	KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;Reactome: R-HSA-1614558;KEGG: 00430+1.13.11.20	"Cysteine and methionine metabolism";"Taurine biosynthesis I";"Degradation of cysteine and homocysteine";"Taurine and hypotaurine metabolism"
XP_016992712.1	33	Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-69273;Reactome: R-HSA-6781827;Reactome: R-HSA-69231;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-69656;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-8939236;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-69202;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-73762;Reactome: R-HSA-6796648	"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"Cyclin A/B1/B2 associated events during G2/M transition";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cyclin D associated events in G1";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"mRNA Capping";"Cyclin E associated events during G1/S transition";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes"
XP_017004421.2	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_017012448.2	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_044251672.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_044250231.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_017014800.1	12	Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-9017802;Reactome: R-HSA-977225;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-2979096	"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"Noncanonical activation of NOTCH3";"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_017012892.2	5	MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism"
XP_044248705.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_017008281.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_017007564.2	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_017004603.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_017013182.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044251270.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_017015766.2	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_017016012.1	5	KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;Reactome: R-HSA-975578;MetaCyc: PWY-7426	"Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_017002887.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_017000566.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_017005678.2	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_017005365.2	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_044250165.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_017010414.2	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_016992335.2	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_017010179.1	6	Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;MetaCyc: PWY-6118;MetaCyc: PWY-6952;MetaCyc: PWY-4261	"Synthesis of PA";"Glycerophospholipid metabolism";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Glycerol degradation I"
XP_017015001.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_017001560.2	6	Reactome: R-HSA-9029569;Reactome: R-HSA-9022537;Reactome: R-HSA-3214815;Reactome: R-HSA-9022692;Reactome: R-HSA-9609690;Reactome: R-HSA-1989781	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HDACs deacetylate histones";"Regulation of MECP2 expression and activity";"HCMV Early Events";"PPARA activates gene expression"
XP_016996066.2	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_017015941.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_017010301.2	1	Reactome: R-HSA-5676934	"Protein repair"
XP_017009309.2	6	Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949	"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin"
XP_017011392.2	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_017006405.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559	"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Glutathione metabolism";"Glutathione degradation (DUG pathway"
XP_017005026.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_016996945.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Aggrephagy";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation"
XP_044251985.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_044250465.1	3	MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors"
XP_017001864.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_016993537.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_017001678.2	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_016999631.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044251994.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_017005634.2	5	KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22	"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Sphingolipid metabolism";"Galactose metabolism"
XP_017010684.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_017004984.2	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_017008292.2	4	Reactome: R-HSA-2408557;MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2;KEGG: 00450+2.9.1.2	"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_017008340.2	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_017005565.2	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_016994001.2	12	Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-9013695;Reactome: R-HSA-3214847;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408	"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation"
XP_044252277.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_017014818.2	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_017004990.2	14	MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602	"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_017006347.2	4	MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32	"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism"
XP_016999166.2	6	Reactome: R-HSA-977347;KEGG: 00270+2.6.1.52;KEGG: 00260+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00750+2.6.1.52;KEGG: 00680+2.6.1.52	"Serine biosynthesis";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Vitamin B6 metabolism";"Methane metabolism"
XP_017008902.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044250549.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017011720.1	14	KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-8051	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I"
XP_016992788.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-6798695	"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Neutrophil degranulation"
XP_017013882.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_017003351.2	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_017009292.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044248756.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044249425.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_017001009.2	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_017011109.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016994582.2	17	Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9633012	"Selenocysteine synthesis";"Viral mRNA Translation";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_016994741.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_017002907.2	3	Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45;KEGG: 00511+3.2.1.45	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Other glycan degradation"
XP_017006492.2	7	Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159	"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling"
XP_044250092.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_044251989.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_016993806.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_017014573.2	4	KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943;MetaCyc: PWY-7221	"Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis"
XP_016998563.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_017004225.2	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_017000575.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_017009440.2	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016999491.2	13	Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-168638;Reactome: R-HSA-975163;Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-9014325;Reactome: R-HSA-5357956;Reactome: R-HSA-450302;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-937072;Reactome: R-HSA-450321	"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"activated TAK1 mediates p38 MAPK activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_017001880.2	4	KEGG: 00510+2.4.1.131;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)"
XP_017007608.2	5	Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827	"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_017011608.2	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_017013554.2	10	KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11;KEGG: 00330+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00332+2.7.2.11+1.2.1.41	"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis"
XP_017006060.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events";"G-protein activation";"G alpha (i) signalling events"
XP_017013866.2	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_016993369.1	14	Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-1632852;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-5620924;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Macroautophagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Intraflagellar transport";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_017001579.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_017001068.2	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_017015326.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016994764.1	57	Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-69017	"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6"
XP_017012322.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016996968.1	3	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198;Reactome: R-HSA-8854214	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs";"TBC/RABGAPs"
XP_017007533.2	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_017009337.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016998104.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_017001715.2	7	Reactome: R-HSA-9018676;Reactome: R-HSA-2142691;Reactome: R-HSA-6798695;Reactome: R-HSA-9020265;Reactome: R-HSA-9023661;Reactome: R-HSA-9018896;Reactome: R-HSA-9018681	"Biosynthesis of D-series resolvins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Neutrophil degranulation";"Biosynthesis of aspirin-triggered D-series resolvins";"Biosynthesis of E-series 18(R)-resolvins";"Biosynthesis of E-series 18(S)-resolvins";"Biosynthesis of protectins"
XP_016999540.2	6	Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Neutrophil degranulation";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_017014599.2	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_017015489.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_044248485.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017008826.2	4	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-418594	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"G alpha (i) signalling events"
XP_016994504.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016997563.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_016996075.2	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_017010942.2	3	Reactome: R-HSA-204174;Reactome: R-HSA-8963684;Reactome: R-HSA-156590	"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism";"Glutathione conjugation"
XP_017008741.2	8	MetaCyc: PWY-7817;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;MetaCyc: PWY-5668;MetaCyc: PWY-5269;KEGG: 00564+3.1.3.27;Reactome: R-HSA-1483148;KEGG: 05235+3.1.3.16	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"Synthesis of PG";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044251363.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_016993651.2	5	Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-532668;Reactome: R-HSA-8957275;Reactome: R-HSA-879415	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling"
XP_016998727.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016996785.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016993106.2	7	Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_017007566.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_017007467.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762	"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation"
XP_017005718.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_017009434.2	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_044248592.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017012645.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016992992.2	1	Reactome: R-HSA-5676934	"Protein repair"
XP_017011913.1	10	Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-6807505	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes"
XP_017009872.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_016999945.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016999057.2	6	Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-1250196;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-418597	"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"SHC1 events in ERBB2 signaling";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events"
XP_016995869.2	6	Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-69473	"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint"
XP_017010052.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016993830.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_017010494.2	6	Reactome: R-HSA-5651801;Reactome: R-HSA-73933;Reactome: R-HSA-110362;Reactome: R-HSA-110357;Reactome: R-HSA-110373;Reactome: R-HSA-73930	"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"
XP_016993388.2	5	Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;MetaCyc: PWY-6853;Reactome: R-HSA-389661;KEGG: 00250+1.2.1.88	"Proline catabolism";"Arginine and proline metabolism";"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation";"Alanine, aspartate and glutamate metabolism"
XP_017014083.1	17	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-8953750;Reactome: R-HSA-5693616;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-75035;Reactome: R-HSA-6796648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-69601;KEGG: 04151+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-1433557;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Transcriptional Regulation by E2F6";"Presynaptic phase of homologous DNA pairing and strand exchange";"mTOR signaling pathway";"Human cytomegalovirus infection";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Transcription of DNA Repair Genes";"Human papillomavirus infection";"G2/M DNA damage checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"PI3K-Akt signaling pathway";"Activation of ATR in response to replication stress";"Signaling by SCF-KIT";"Human immunodeficiency virus 1 infection"
XP_017013923.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_017015082.2	4	MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21	"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism"
XP_017004029.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_017005006.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_017004644.2	7	Reactome: R-HSA-5362517;Reactome: R-HSA-389661;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00010+2.3.1.12;KEGG: 00020+2.3.1.12;KEGG: 00620+2.3.1.12	"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism"
XP_017014581.2	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016995680.2	3	MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1	"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation"
XP_017010837.2	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_016999819.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Viral mRNA Translation";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_044249059.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_017000433.2	5	MetaCyc: PWY-7511;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"Protein ubiquitination";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_017003818.2	8	Reactome: R-HSA-4551638;Reactome: R-HSA-8943724;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-212300	"SUMOylation of chromatin organization proteins";"Regulation of PTEN gene transcription";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA"
XP_017012359.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016998401.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_016994871.2	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_016993755.2	9	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-110314;Reactome: R-HSA-6781823	"Neddylation";"DNA Damage Recognition in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex"
XP_017012245.2	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_016999306.2	29	Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-5696395;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-5696400	"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"RNA Polymerase I Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual Incision in GG-NER"
XP_016996360.2	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_017013519.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_017007057.1	5	MetaCyc: PWY-5514;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6906	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin derivatives degradation"
XP_017006411.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_016998764.2	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_017006527.1	27	Reactome: R-HSA-4641262;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5358747;KEGG: 04151+2.7.11.1;Reactome: R-HSA-399956;Reactome: R-HSA-75815;KEGG: 05170+2.7.11.1;Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5250924;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-5467337;Reactome: R-HSA-5610785;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-198323	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Human papillomavirus infection";"S33 mutants of beta-catenin aren't phosphorylated";"PI3K-Akt signaling pathway";"CRMPs in Sema3A signaling";"Ubiquitin-dependent degradation of Cyclin D";"Human immunodeficiency virus 1 infection";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"mTOR signaling pathway";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"APC truncation mutants have impaired AXIN binding";"GLI3 is processed to GLI3R by the proteasome";"Relaxin signaling pathway";"Thermogenesis";"Regulation of HSF1-mediated heat shock response";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"AKT phosphorylates targets in the cytosol"
XP_044251030.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_017014462.2	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_017008132.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_017011183.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_017015950.2	4	MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175	"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Threonine catabolism"
XP_017005140.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016996094.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_017001602.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_044252005.1	4	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255	"HATs acetylate histones";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis"
XP_016995712.2	30	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-1170546;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-2644607;Reactome: R-HSA-5684264;Reactome: R-HSA-187577;Reactome: R-HSA-2122947;Reactome: R-HSA-5676590;Reactome: R-HSA-400253;Reactome: R-HSA-5607764;Reactome: R-HSA-9604323;Reactome: R-HSA-917937;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-69231;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-2565942	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Neddylation";"Downstream TCR signaling";"Prolactin receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"SCF(Skp2)-mediated degradation of p27/p21";"NOTCH1 Intracellular Domain Regulates Transcription";"NIK-->noncanonical NF-kB signaling";"Circadian Clock";"CLEC7A (Dectin-1) signaling";"Negative regulation of NOTCH4 signaling";"Iron uptake and transport";"Orc1 removal from chromatin";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cyclin D associated events in G1";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Regulation of PLK1 Activity at G2/M Transition"
XP_016993684.2	17	MetaCyc: PWY-5966-1;Reactome: R-HSA-196780;Reactome: R-HSA-200425;MetaCyc: PWY-5789;KEGG: 00254+6.4.1.2;Reactome: R-HSA-163765;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;KEGG: 00061+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-4381	"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Biotin transport and metabolism";"Carnitine metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Aflatoxin biosynthesis";"ChREBP activates metabolic gene expression";"Propanoate metabolism";"3-hydroxypropanoate cycle";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Carbon fixation pathways in prokaryotes";"Candicidin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)"
XP_017012615.2	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_017006892.1	3	Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619	"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI"
XP_016995842.2	3	KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619;Reactome: R-HSA-74217	"Purine metabolism";"Adenine and adenosine salvage VI";"Purine salvage"
XP_017010027.2	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_017007529.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044252120.1	7	KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043;Reactome: R-HSA-174403;MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255;Reactome: R-HSA-5578999	"Glutathione metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_017010004.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017005734.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016996397.2	17	Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-69166;Reactome: R-HSA-6782135;Reactome: R-HSA-174417;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-6782210;Reactome: R-HSA-174414;Reactome: R-HSA-174437;Reactome: R-HSA-69183;Reactome: R-HSA-5656169	"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate";"Dual incision in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the lagging strand";"Termination of translesion DNA synthesis"
XP_017005273.2	4	Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-1170546;Reactome: R-HSA-982772	"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Prolactin receptor signaling";"Growth hormone receptor signaling"
XP_044252211.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_017016285.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017002392.2	5	Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310	"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Fanconi Anemia Pathway"
XP_017016089.2	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_017013889.1	16	Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-9010553;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-1234176;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167200	"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of expression of SLITs and ROBOs";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_016999656.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044251355.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_017008993.2	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_017014643.2	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_016998688.2	14	Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601	"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_044251501.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_016998016.2	29	Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-73772	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Promoter Escape"
XP_017005320.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_044252015.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_017000389.1	57	Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-1169091	"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells"
XP_016994735.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017012388.2	8	Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-5099900;Reactome: R-HSA-432720;Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"WNT5A-dependent internalization of FZD4";"Lysosome Vesicle Biogenesis";"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis"
XP_016993715.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_017008141.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044250643.1	5	KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_017001798.2	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_017013714.2	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_017015804.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_017004660.2	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_016997179.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_017009977.2	6	Reactome: R-HSA-196780;MetaCyc: PWY-6987;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181	"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_017013156.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_017012101.2	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_017000478.2	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_017007306.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017010133.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017007751.2	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_016997715.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016993172.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_017012210.1	56	Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-202424	"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Downstream TCR signaling"
XP_016998059.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016999003.2	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_016998035.2	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_044248824.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_017007886.2	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_017010776.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_017007033.2	10	Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-9018519	"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Estrogen-dependent gene expression"
XP_017009991.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins"
XP_016993934.2	18	Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"mTORC1-mediated signalling";"Translation initiation complex formation";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
XP_016995639.2	3	KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_016996285.1	19	Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244	"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"RAF activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Long-term potentiation"
XP_016993371.1	14	Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-1632852;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5620924;Reactome: R-HSA-9646399	"MHC class II antigen presentation";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Macroautophagy";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Intraflagellar transport";"Aggrephagy"
XP_016999070.2	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_016996721.2	5	MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18	"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism"
XP_044248530.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_017001426.2	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_017016202.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
XP_016994604.2	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_017013538.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_017003112.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016992582.2	22	Reactome: R-HSA-5673000;Reactome: R-HSA-2467813;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-2500257;Reactome: R-HSA-389513;Reactome: R-HSA-6811558;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-195253;Reactome: R-HSA-5675221;Reactome: R-HSA-141444;Reactome: R-HSA-5358747;Reactome: R-HSA-432142;Reactome: R-HSA-9648025;Reactome: R-HSA-4641262	"RAF activation";"Separation of Sister Chromatids";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Degradation of beta-catenin by the destruction complex";"Negative regulation of MAPK pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S33 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"EML4 and NUDC in mitotic spindle formation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_044251818.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_017005188.2	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_016998859.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_017008232.2	2	Reactome: R-HSA-5627123;Reactome: R-HSA-8856828	"RHO GTPases activate PAKs";"Clathrin-mediated endocytosis"
XP_017014323.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_017000468.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017005339.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_017000069.2	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;MetaCyc: PWY-7511;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_017016107.2	5	Reactome: R-HSA-4755579;MetaCyc: PWY-6129;Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94;Reactome: R-HSA-446199	"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Dolichol and dolichyl phosphate biosynthesis";"Androgen biosynthesis";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_044249472.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_017007908.2	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_016999090.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_016993038.2	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_016997517.2	9	Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape"
XP_016999278.2	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_017007818.2	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_044251549.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_017006355.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_017004666.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017001198.2	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_017007183.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016992884.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_044248486.1	7	Reactome: R-HSA-110362;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-5685939;Reactome: R-HSA-2173795	"POLB-Dependent Long Patch Base Excision Repair";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"HDR through MMEJ (alt-NHEJ)";"Downregulation of SMAD2/3:SMAD4 transcriptional activity"
XP_016992631.2	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_017010789.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_017009765.2	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_044249340.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_044249542.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_016996231.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016993070.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_017003256.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016992773.2	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_017006061.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_017011133.2	12	Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001	"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Synaptic adhesion-like molecules";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade"
XP_017008082.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016995113.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-6804115;Reactome: R-HSA-5617472	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_017003051.2	3	Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271	"GDP-fucose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_017003527.2	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_044248608.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_017003265.2	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016996014.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_017001291.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_017007614.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016995243.2	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_016995198.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017015424.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044250840.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016993664.2	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_016995872.1	29	Reactome: R-HSA-75953;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-73772;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-73762	"RNA Polymerase II Transcription Initiation";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"mRNA Capping";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation"
XP_044252048.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_017005272.2	4	Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-1170546;Reactome: R-HSA-982772	"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Prolactin receptor signaling";"Growth hormone receptor signaling"
XP_017001852.2	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_017012882.2	26	Reactome: R-HSA-2122947;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-918233;Reactome: R-HSA-3134973;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568;Reactome: R-HSA-3214847;Reactome: R-HSA-8866907;Reactome: R-HSA-9013695;Reactome: R-HSA-1368082;Reactome: R-HSA-5621575;Reactome: R-HSA-9617629;Reactome: R-HSA-1912408;Reactome: R-HSA-9614657;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-1989781;Reactome: R-HSA-8941856;Reactome: R-HSA-201722;Reactome: R-HSA-1234158;Reactome: R-HSA-400253	"NOTCH1 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF3-dependent IRF activation pathway";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"Estrogen-dependent gene expression";"Attenuation phase";"HATs acetylate histones";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH4 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"CD209 (DC-SIGN) signaling";"Regulation of FOXO transcriptional activity by acetylation";"Pre-NOTCH Transcription and Translation";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"RUNX3 regulates NOTCH signaling";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression by Hypoxia-inducible Factor";"Circadian Clock"
XP_017011155.2	8	Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-9609736	"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors"
XP_017006959.2	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016997058.1	4	Reactome: R-HSA-8934903;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-936440	"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling"
XP_017013438.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria"
XP_016995683.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_017012347.2	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_017000776.2	7	KEGG: 00250+4.3.2.2;MetaCyc: PWY-6123;MetaCyc: PWY-7234;MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-7219;KEGG: 00230+4.3.2.2	"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_044251576.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044248914.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017015271.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_017006964.2	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_017007916.1	24	Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332	"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Kinesins";"Gap junction assembly";"Mitotic Prometaphase";"Recycling pathway of L1";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin"
XP_016999030.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016993373.1	27	Reactome: R-HSA-674695;Reactome: R-HSA-77595;Reactome: R-HSA-191859;Reactome: R-HSA-975957;Reactome: R-HSA-167242;Reactome: R-HSA-159230;Reactome: R-HSA-111367;Reactome: R-HSA-9010553;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-77588;Reactome: R-HSA-159236;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-159227;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-112382;Reactome: R-HSA-6803529;Reactome: R-HSA-72187;Reactome: R-HSA-167200;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-975956	"RNA Polymerase II Pre-transcription Events";"Processing of Intronless Pre-mRNAs";"snRNP Assembly";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transport of the SLBP Dependant Mature mRNA";"SLBP independent Processing of Histone Pre-mRNAs";"Regulation of expression of SLITs and ROBOs";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Transport of the SLBP independent Mature mRNA";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"Formation of RNA Pol II elongation complex";"FGFR2 alternative splicing";"mRNA 3'-end processing";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_017005361.2	4	Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation"
XP_017007532.2	57	Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-69481	"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Separation of Sister Chromatids";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints"
XP_016995929.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_017012005.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_044250330.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016997775.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_017003229.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_017008397.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_017005053.1	40	Reactome: R-HSA-73776;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-167243;Reactome: R-HSA-6782135;Reactome: R-HSA-167238;Reactome: R-HSA-72163;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-6782210;Reactome: R-HSA-168325;Reactome: R-HSA-203927;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-72165;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-5578749;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-8851708;Reactome: R-HSA-73779	"RNA Polymerase II Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated HIV elongation arrest and recovery";"Dual incision in TC-NER";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Major Pathway";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Viral Messenger RNA Synthesis";"MicroRNA (miRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Minor Pathway";"mRNA Capping";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"Transcriptional regulation by small RNAs";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_017000084.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789;Reactome: R-HSA-917937	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"UCH proteinases";"TGF-beta receptor signaling activates SMADs";"Iron uptake and transport"
XP_044251286.1	4	Reactome: R-HSA-8875555;Reactome: R-HSA-186763;Reactome: R-HSA-8875656;Reactome: R-HSA-912631	"MET activates RAP1 and RAC1";"Downstream signal transduction";"MET receptor recycling";"Regulation of signaling by CBL"
XP_017009830.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044249782.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017011221.2	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_044252266.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_016995967.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044251855.1	56	Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174184	"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"Separation of Sister Chromatids";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_016997133.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_017001706.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017001676.2	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_017008418.2	7	Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-156711	"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events"
XP_017012925.1	13	Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-6804757;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-389357;Reactome: R-HSA-9639288;Reactome: R-HSA-5218920;Reactome: R-HSA-1632852;Reactome: R-HSA-1257604;Reactome: R-HSA-5628897	"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"Regulation of TP53 Degradation";"mTOR signalling";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"CD28 dependent PI3K/Akt signaling";"Amino acids regulate mTORC1";"VEGFR2 mediated vascular permeability";"Macroautophagy";"PIP3 activates AKT signaling";"TP53 Regulates Metabolic Genes"
XP_016995673.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_016994093.2	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_016996882.2	6	Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772	"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape"
XP_017015696.2	7	KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Myo-inositol biosynthesis";"Streptomycin biosynthesis"
XP_044250212.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_017006961.2	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_017013259.2	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_044249662.1	42	Reactome: R-HSA-9616222;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-171306;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-8939236;Reactome: R-HSA-427389;Reactome: R-HSA-912446;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-5693607;Reactome: R-HSA-2299718;Reactome: R-HSA-5250924;Reactome: R-HSA-5693565;Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-5693571;Reactome: R-HSA-201722;Reactome: R-HSA-3214815;Reactome: R-HSA-3214858;Reactome: R-HSA-69473;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-3214842;Reactome: R-HSA-1912408;Reactome: R-HSA-9610379;Reactome: R-HSA-5625886;Reactome: R-HSA-110329;Reactome: R-HSA-1221632;Reactome: R-HSA-977225;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580	"Transcriptional regulation of granulopoiesis";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Packaging Of Telomere Ends";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"HCMV Early Events";"PRC2 methylates histones and DNA";"Estrogen-dependent gene expression";"DNA methylation";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic recombination";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"Processing of DNA double-strand break ends";"Condensation of Prophase Chromosomes";"B-WICH complex positively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Nonhomologous End-Joining (NHEJ)";"Formation of the beta-catenin:TCF transactivating complex";"HDACs deacetylate histones";"RMTs methylate histone arginines";"G2/M DNA damage checkpoint";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDMs demethylate histones";"Pre-NOTCH Transcription and Translation";"HCMV Late Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Cleavage of the damaged pyrimidine";"Meiotic synapsis";"Amyloid fiber formation";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence"
XP_017005978.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_016997193.1	4	Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841	"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)"
XP_017000947.2	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016992509.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_017005723.2	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_017006226.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017001861.2	11	Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-3371497;Reactome: R-HSA-380270	"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes"
XP_044252210.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_017005988.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044251376.1	3	Reactome: R-HSA-212676;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361	"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins"
XP_017011712.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_017005427.1	17	Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Translation initiation complex formation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_017008824.2	4	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases"
XP_016997458.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_017001394.2	8	MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;Reactome: R-HSA-5683826;KEGG: 00230+3.5.4.4;Reactome: R-HSA-74217;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-7179	"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Surfactant metabolism";"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I"
XP_017002264.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_017009447.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
XP_044251510.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_017013566.2	3	Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5656169	"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis"
XP_044251464.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044248837.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_016993582.2	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_017002251.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_017014558.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_017011698.1	13	Reactome: R-HSA-1855204;Reactome: R-HSA-2871809;MetaCyc: PWY-7039;Reactome: R-HSA-2424491;KEGG: 04070+3.1.4.11;Reactome: R-HSA-9027277;MetaCyc: PWY-6351;Reactome: R-HSA-2029485;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-2871796;Reactome: R-HSA-202433;KEGG: 00562+3.1.4.11	"Synthesis of IP3 and IP4 in the cytosol";"FCERI mediated Ca+2 mobilization";"Phosphatidate metabolism, as a signaling molecule";"DAP12 signaling";"Phosphatidylinositol signaling system";"Erythropoietin activates Phospholipase C gamma (PLCG)";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Role of phospholipids in phagocytosis";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"FCERI mediated MAPK activation";"Generation of second messenger molecules";"Inositol phosphate metabolism"
XP_017000793.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_017004625.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_017010428.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016992705.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_017007176.2	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_017006211.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_016996441.2	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_017008174.2	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers"
XP_017011359.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_017005732.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580	"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence"
XP_017011437.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017009076.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017011657.2	4	KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17	"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism"
XP_044249110.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_017013672.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017004142.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016996273.2	4	Reactome: R-HSA-1799339;Reactome: R-HSA-446203;Reactome: R-HSA-6798695;Reactome: R-HSA-879415	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation";"Neutrophil degranulation";"Advanced glycosylation endproduct receptor signaling"
XP_017004569.2	7	MetaCyc: PWY-6614;MetaCyc: PWY-3841;Reactome: R-HSA-69205;Reactome: R-HSA-1474151;KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3;Reactome: R-HSA-196757	"Tetrahydrofolate biosynthesis";"Folate transformations II (plants)";"G1/S-Specific Transcription";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"One carbon pool by folate";"Folate biosynthesis";"Metabolism of folate and pterines"
XP_044250194.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_016996438.2	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_017001943.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016994873.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_016996015.2	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_017002892.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-6798695;Reactome: R-HSA-1660499;Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Neutrophil degranulation";"Synthesis of PIPs at the plasma membrane";"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_016997482.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017013876.2	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_017000742.2	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_044251990.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_016992522.2	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_044250556.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
XP_017010296.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_017006190.2	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_016995347.2	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_017002210.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_017012620.1	13	Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-3371511;Reactome: R-HSA-382556;Reactome: R-HSA-110320;Reactome: R-HSA-5689896;Reactome: R-HSA-6798695;Reactome: R-HSA-532668;Reactome: R-HSA-8876725;Reactome: R-HSA-5678895;Reactome: R-HSA-8866654;Reactome: R-HSA-9646399;Reactome: R-HSA-5689877	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"HSF1 activation";"ABC-family proteins mediated transport";"Translesion Synthesis by POLH";"Ovarian tumor domain proteases";"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein methylation";"Defective CFTR causes cystic fibrosis";"E3 ubiquitin ligases ubiquitinate target proteins";"Aggrephagy";"Josephin domain DUBs"
XP_016999542.2	9	MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-7003;MetaCyc: PWY-8004;KEGG: 00710+1.2.1.12;MetaCyc: PWY-1042;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70263;Reactome: R-HSA-70171	"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Glycolysis"
XP_017013154.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016998825.2	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_017012207.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_016992718.2	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_016995398.2	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_017012641.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis"
XP_017002758.2	5	MetaCyc: PWY-7180;MetaCyc: PWY-8060;KEGG: 00030+4.1.2.4;Reactome: R-HSA-6798695;Reactome: R-HSA-71336	"2-deoxy-alpha-D-ribose 1-phosphate degradation";"2-deoxy-D-ribose degradation I";"Pentose phosphate pathway";"Neutrophil degranulation";"Pentose phosphate pathway"
XP_017012191.2	2	Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Formation of apoptosome";"Regulation of the apoptosome activity"
XP_016999032.2	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_016994776.2	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_017008138.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044249488.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016994778.2	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_017013446.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_017015926.1	6	KEGG: 00630+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6	"Glyoxylate and dicarboxylate metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Peroxisomal protein import";"Neutrophil degranulation";"Tryptophan metabolism"
XP_017004597.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044248937.1	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
XP_017015431.1	1	Reactome: R-HSA-416476	"G alpha (q) signalling events"
XP_016996817.2	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_044250455.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_017008827.2	4	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases"
XP_017009150.2	4	KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;Reactome: R-HSA-70688;MetaCyc: PWY-5737	"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis"
XP_016995514.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975957	"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_017012983.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_017006437.1	4	Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_017011379.1	12	Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00010+4.1.2.13;MetaCyc: PWY-5484	"Glycolysis";"Fructose and mannose metabolism";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)"
XP_016996710.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_016997522.2	9	Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167162	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape"
XP_017015111.2	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_016995245.1	5	Reactome: R-HSA-5218921;Reactome: R-HSA-5658442;Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-186763	"VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs";"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Downstream signal transduction"
XP_017014623.2	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_017003100.2	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_016995595.2	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_044249418.1	42	Reactome: R-HSA-73772;Reactome: R-HSA-912446;Reactome: R-HSA-427389;Reactome: R-HSA-73728;Reactome: R-HSA-5693607;Reactome: R-HSA-3214841;Reactome: R-HSA-8939236;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-3214847;Reactome: R-HSA-212300;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-9609690;Reactome: R-HSA-171306;Reactome: R-HSA-8936459;Reactome: R-HSA-9616222;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-2559580;Reactome: R-HSA-5625886;Reactome: R-HSA-110329;Reactome: R-HSA-9610379;Reactome: R-HSA-977225;Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-3214842;Reactome: R-HSA-1912408;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-201722;Reactome: R-HSA-3214815;Reactome: R-HSA-3214858;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-2299718;Reactome: R-HSA-5250924	"RNA Polymerase I Promoter Escape";"Meiotic recombination";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Opening";"Processing of DNA double-strand break ends";"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"DNA methylation";"HATs acetylate histones";"PRC2 methylates histones and DNA";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"HCMV Early Events";"Packaging Of Telomere Ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation of granulopoiesis";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Oxidative Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Cleavage of the damaged pyrimidine";"HCMV Late Events";"Amyloid fiber formation";"Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HDMs demethylate histones";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex";"HDACs deacetylate histones";"RMTs methylate histone arginines";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Condensation of Prophase Chromosomes";"B-WICH complex positively regulates rRNA expression"
XP_017013137.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016999290.2	11	Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-164378	"Glucagon signaling in metabolic regulation";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation in glucagon signalling"
XP_017000975.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_017002066.2	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_017003292.2	16	Reactome: R-HSA-1810476;Reactome: R-HSA-975871;Reactome: R-HSA-5602498;Reactome: R-HSA-1257604;Reactome: R-HSA-975110;Reactome: R-HSA-3134963;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5603037;Reactome: R-HSA-166058;Reactome: R-HSA-5602680;Reactome: R-HSA-5603041;Reactome: R-HSA-975138;Reactome: R-HSA-6811558;Reactome: R-HSA-975155;Reactome: R-HSA-209543	"RIP-mediated NFkB activation via ZBP1";"MyD88 cascade initiated on plasma membrane";"MyD88 deficiency (TLR2/4)";"PIP3 activates AKT signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"ER-Phagosome pathway";"Interleukin-1 signaling";"IRAK4 deficiency (TLR5)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 deficiency (TLR5)";"IRAK4 deficiency (TLR2/4)";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88 dependent cascade initiated on endosome";"p75NTR recruits signalling complexes"
XP_017004183.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_017011739.2	4	Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_017014130.2	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_016994853.1	30	Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-400253;Reactome: R-HSA-9604323;Reactome: R-HSA-917937;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-2565942;Reactome: R-HSA-8854050;Reactome: R-HSA-69231;Reactome: R-HSA-2871837;Reactome: R-HSA-1170546;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-1169091;Reactome: R-HSA-2644607;Reactome: R-HSA-5684264;Reactome: R-HSA-187577;Reactome: R-HSA-2122947;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785	"Orc1 removal from chromatin";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Circadian Clock";"Negative regulation of NOTCH4 signaling";"Iron uptake and transport";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Regulation of PLK1 Activity at G2/M Transition";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cyclin D associated events in G1";"FCERI mediated NF-kB activation";"Prolactin receptor signaling";"Downstream TCR signaling";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of NF-kappaB in B cells";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"SCF(Skp2)-mediated degradation of p27/p21";"NOTCH1 Intracellular Domain Regulates Transcription";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome"
XP_017010783.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016995230.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016992766.2	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_017013715.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_017004599.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044249877.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_017005489.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_017016011.1	14	KEGG: 00280+2.6.1.42;MetaCyc: PWY-5057;MetaCyc: PWY-5078;MetaCyc: PWY-5108;MetaCyc: PWY-5101;MetaCyc: PWY-7767;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00290+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5076;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5104;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"L-valine degradation II";"L-isoleucine degradation II";"L-isoleucine biosynthesis V";"L-isoleucine biosynthesis II";"L-leucine degradation IV (Stickland reaction)";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis III";"Valine, leucine and isoleucine biosynthesis";"Cysteine and methionine metabolism";"L-leucine degradation III";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis IV";"Branched-chain amino acid catabolism"
XP_016995774.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017008468.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-428930	"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor"
XP_016995160.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_017005910.2	6	KEGG: 00720+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.3	"Carbon fixation pathways in prokaryotes";"Mitochondrial protein import";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)"
XP_017009412.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017014912.2	10	MetaCyc: PWY-6174;Reactome: R-HSA-1989781;KEGG: 00650+2.3.3.10;KEGG: 00900+2.3.3.10;MetaCyc: PWY-922;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7571;MetaCyc: PWY-7524;MetaCyc: PWY-7391;KEGG: 00280+2.3.3.10	"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Butanoate metabolism";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Synthesis and degradation of ketone bodies";"Ferrichrome A biosynthesis";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Valine, leucine and isoleucine degradation"
XP_017006407.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_017008171.2	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers"
XP_044249965.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_017015810.2	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_016999081.2	3	KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067;Reactome: R-HSA-3322077	"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis"
XP_017002029.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044251006.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_017012450.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_017003629.2	5	Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772	"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape"
XP_017011347.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_017008395.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016999496.2	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_017006680.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_016996296.1	7	KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-2151201;Reactome: R-HSA-8949613	"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"Photosynthesis";"ATP biosynthesis";"Transcriptional activation of mitochondrial biogenesis";"Cristae formation"
XP_016996238.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_016992904.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017006277.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72649	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Viral mRNA Translation";"Translation initiation complex formation"
XP_017007513.2	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_017007468.2	8	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_016998834.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016996727.2	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_016996689.2	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_016996616.2	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_016994676.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017007521.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044251881.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016993293.2	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_044251003.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_017005938.2	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_017015694.1	13	MetaCyc: PWY-6672;Reactome: R-HSA-71384;MetaCyc: PWY-7118;MetaCyc: PWY-5133;KEGG: 00630+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-7857;KEGG: 00620+6.2.1.1;KEGG: 00010+6.2.1.1;KEGG: 00720+6.2.1.1	"Cis-genanyl-coa degradation";"Ethanol oxidation";"Chitin degradation to ethanol";"Colupulone and cohumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Propanoate metabolism";"Lupulone and humulone biosynthesis";"Methane metabolism";"L-isoleucine biosynthesis V";"Adlupulone and adhumulone biosynthesis";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Carbon fixation pathways in prokaryotes"
XP_044251379.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016992993.2	1	Reactome: R-HSA-5676934	"Protein repair"
XP_017000700.2	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_016998091.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_044250528.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_017011606.2	14	KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-7411;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7589;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-7782	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Plasmalogen biosynthesis"
XP_017007910.2	3	Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-9634638	"RHO GTPases Activate Formins";"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling"
XP_016999662.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016999557.2	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_016993253.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016996434.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_017009204.2	3	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_017015893.2	15	Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-5467337;Reactome: R-HSA-5689896;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5467333;Reactome: R-HSA-195253;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-5358749;Reactome: R-HSA-111465;Reactome: R-HSA-5339716	"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"APC truncation mutants are not K63 polyubiquitinated";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin"
XP_017005337.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_017011272.2	9	Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape"
XP_017009227.2	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_017003726.2	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_017005508.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044248655.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_016994580.2	16	Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-174048	"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B"
XP_017008168.2	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers"
XP_017012945.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_017010348.2	8	Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-68962	"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex"
XP_017013336.2	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_044248694.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_017002165.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016993761.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_017005676.2	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_017009239.2	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_017013895.2	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_017006344.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016993978.2	4	KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;MetaCyc: PWY-7268	"Glutathione metabolism";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_016992726.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017010055.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016995715.2	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_044249492.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_017004982.2	14	MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7724	"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_017000953.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017005336.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_017010818.2	18	Reactome: R-HSA-1482801;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-7409;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4	"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Plasmalogen degradation";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism"
XP_017003497.2	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_016994915.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_016999635.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044252018.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_044251729.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_017006734.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72649	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"Translation initiation complex formation"
XP_017012746.1	4	KEGG: 00860+1.14.14.18;MetaCyc: PWY-5874;Reactome: R-HSA-917937;Reactome: R-HSA-189483	"Porphyrin and chlorophyll metabolism";"Heme degradation I";"Iron uptake and transport";"Heme degradation"
XP_017005068.2	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_044249599.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016994785.2	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_017013900.2	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_017004613.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_017008425.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016999691.1	13	Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5627117;Reactome: R-HSA-416572;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-3928663;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"RHO GTPases Activate ROCKs";"Sema4D induced cell migration and growth-cone collapse";"mTOR signaling pathway";"Human cytomegalovirus infection";"EPHB-mediated forward signaling";"EPHA-mediated growth cone collapse";"Thermogenesis";"Relaxin signaling pathway"
XP_016996152.2	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_017005245.2	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_017008359.2	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_017003537.2	8	KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-6611;MetaCyc: PWY-7179;Reactome: R-HSA-6798695	"Purine metabolism";"Surfactant metabolism";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation"
XP_017003093.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_017003691.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_044248661.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_017013810.2	7	KEGG: 00562+2.7.8.11;MetaCyc: PWY-7625;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6351;MetaCyc: PWY-6352;Reactome: R-HSA-1483226;KEGG: 00564+2.7.8.11	"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Synthesis of PI";"Glycerophospholipid metabolism"
XP_017014859.2	5	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_044249431.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_017005059.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016999618.2	13	MetaCyc: PWY-5913;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-7254;MetaCyc: PWY-8086;KEGG: 00020+4.2.1.2;Reactome: R-HSA-71403;MetaCyc: PWY-561;KEGG: 00620+4.2.1.2	"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism"
XP_044249849.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_017005444.1	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
XP_017015707.2	9	KEGG: 00790+3.5.4.16;MetaCyc: PWY-6703;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-5664;MetaCyc: PWY-6147;MetaCyc: PWY-7852;MetaCyc: PWY-5663	"Folate biosynthesis";"Preq0 biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis I"
XP_017014625.2	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_017008861.2	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_017004456.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_017004450.2	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_017003906.2	16	MetaCyc: PWY-7384;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.4;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5913;MetaCyc: PWY-5749;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-6728	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"Propanoate metabolism";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Itaconate degradation";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle"
XP_017003486.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017005007.2	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7035	"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis"
XP_017011199.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016996948.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport"
XP_017008343.2	7	MetaCyc: PWY-6352;KEGG: 00562+2.7.1.67;KEGG: 04070+2.7.1.67;MetaCyc: PWY-6351;Reactome: R-HSA-1660499;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516	"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane"
XP_017008825.2	4	Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"G alpha (i) signalling events";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_044250159.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_017001181.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_017009446.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
XP_044251279.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_017013402.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs"
XP_017005166.2	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_017012981.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_017006471.2	4	MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32	"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism"
XP_017006675.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_044249738.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_017005393.2	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_016992517.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017008549.2	42	Reactome: R-HSA-5693607;Reactome: R-HSA-427389;Reactome: R-HSA-912446;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-8939236;Reactome: R-HSA-3214841;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-171306;Reactome: R-HSA-9616222;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-110329;Reactome: R-HSA-5625886;Reactome: R-HSA-9610379;Reactome: R-HSA-977225;Reactome: R-HSA-2559586;Reactome: R-HSA-1221632;Reactome: R-HSA-1912408;Reactome: R-HSA-3214842;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-3214858;Reactome: R-HSA-69473;Reactome: R-HSA-201722;Reactome: R-HSA-3214815;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-110328;Reactome: R-HSA-2299718;Reactome: R-HSA-5250924	"Processing of DNA double-strand break ends";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic recombination";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PKMTs methylate histone lysines";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"Estrogen-dependent gene expression";"DNA methylation";"PRC2 methylates histones and DNA";"HCMV Early Events";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Packaging Of Telomere Ends";"Transcriptional regulation of granulopoiesis";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cleavage of the damaged pyrimidine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HCMV Late Events";"Amyloid fiber formation";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic synapsis";"Pre-NOTCH Transcription and Translation";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"RMTs methylate histone arginines";"G2/M DNA damage checkpoint";"Formation of the beta-catenin:TCF transactivating complex";"HDACs deacetylate histones";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Condensation of Prophase Chromosomes";"B-WICH complex positively regulates rRNA expression"
XP_016996583.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016996149.2	7	Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_044248597.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017007453.2	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_016997997.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_017002393.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-68827	"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Separation of Sister Chromatids";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex"
XP_016992583.2	22	Reactome: R-HSA-6811558;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-2467813;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-432142;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"Separation of Sister Chromatids";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Platelet sensitization by LDL";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins"
XP_017013518.2	1	Reactome: R-HSA-3295583	"TRP channels"
XP_017000120.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_016999465.2	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_044251619.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_017008004.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_017013444.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_017010198.2	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_017007796.2	4	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway"
XP_044251746.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_017011985.2	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_016999585.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288	"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1"
XP_017002067.2	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_017003512.2	4	Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_017006530.1	27	KEGG: 05170+2.7.11.1;Reactome: R-HSA-75815;Reactome: R-HSA-399956;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5250924;Reactome: R-HSA-5674400;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-196299;Reactome: R-HSA-5610785;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3371453	"Human immunodeficiency virus 1 infection";"Ubiquitin-dependent degradation of Cyclin D";"CRMPs in Sema3A signaling";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Human cytomegalovirus infection";"mTOR signaling pathway";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by AKT1 E17K in Cancer";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Beta-catenin phosphorylation cascade";"GLI3 is processed to GLI3R by the proteasome";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Thermogenesis";"Regulation of HSF1-mediated heat shock response"
XP_017006432.1	5	MetaCyc: PWY-7185;MetaCyc: PWY-7177;Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7176	"UTP and CTP dephosphorylation I";"UTP and CTP dephosphorylation II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis"
XP_017015322.2	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_044251357.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_017004858.2	6	Reactome: R-HSA-5654706;Reactome: R-HSA-9028731;Reactome: R-HSA-5654700;Reactome: R-HSA-5673001;Reactome: R-HSA-5654712;Reactome: R-HSA-5654693	"FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR2 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR1 signaling"
XP_017016287.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016994127.2	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_016995838.2	6	MetaCyc: PWY-5484;MetaCyc: PWY-1622;KEGG: 00010+5.4.2.11;KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004	"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Methane metabolism";"Entner-Doudoroff pathway I"
XP_016994066.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_017012634.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_017010159.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_017005497.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017005136.2	26	Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-389977;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690	"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Kinesins";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Post-chaperonin tubulin folding pathway";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"MHC class II antigen presentation";"HCMV Early Events"
XP_017013284.2	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_044252196.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017002325.2	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_044251739.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_017012416.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_017012978.2	3	MetaCyc: PWY-5963;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9	"Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_016994404.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_017002909.2	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_017005789.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_044250160.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_017006238.2	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_016997041.2	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_017012405.2	3	KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562;Reactome: R-HSA-70350	"Fructose and mannose metabolism";"Essential fructosuria";"Fructose catabolism"
XP_016996978.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017003199.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_017008569.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_044248711.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017013786.2	3	MetaCyc: PWY-7511;Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Protein ubiquitination";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017004091.2	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_017012449.2	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_016998861.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_017006223.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_017000142.2	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_017001132.2	6	MetaCyc: PWY-5067;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;Reactome: R-HSA-3322077;Reactome: R-HSA-3878781	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen synthesis";"Glycogen storage disease type IV (GBE1)"
XP_017010298.2	1	Reactome: R-HSA-5676934	"Protein repair"
XP_044249209.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_017015380.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_017005834.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016993230.2	4	Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_017003998.2	20	Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-6804756;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)"
XP_044251757.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016997511.2	8	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540	"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Activation of RAC1"
XP_017010119.2	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_017010418.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_044249680.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_017005883.2	6	Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-73856	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination"
XP_017000158.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_017001707.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017016094.2	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_016999300.2	7	MetaCyc: PWY-6545;KEGG: 00730+3.6.1.15;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7184;MetaCyc: PWY-7185;MetaCyc: PWY-7198;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Thiamine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_017008870.2	6	KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;MetaCyc: PWY-7426	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_017001298.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016995529.2	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_016994852.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_017007795.2	4	MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-7174	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_044251983.1	10	Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932	"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Long-term potentiation";"Synaptic adhesion-like molecules"
XP_016994266.1	10	MetaCyc: PWY-7661;Reactome: R-HSA-4719377;MetaCyc: PWY-7921;Reactome: R-HSA-4719360;MetaCyc: PWY-7979;Reactome: R-HSA-913709;Reactome: R-HSA-4717374;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7922;Reactome: R-HSA-162699	"Protein N-glycosylation (Haloferax volcanii)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Protein O-mannosylation I (yeast)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation of mucins";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"N-Glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Synthesis of dolichyl-phosphate mannose"
XP_044250100.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_017008366.2	5	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
XP_017002550.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016996280.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"RAF activation";"Long-term potentiation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors"
XP_017006795.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_017014838.1	57	Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5678895	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Degradation of AXIN";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis"
XP_017014438.2	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_017004602.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044248607.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_016993561.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016997391.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_016995699.2	9	Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-445355	"Platelet degranulation";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction"
XP_044251889.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_017000153.2	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_044248895.1	4	Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788	"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling"
XP_017006454.1	11	MetaCyc: PWY-6969;MetaCyc: PWY-6549;KEGG: 00480+1.1.1.42;KEGG: 00720+1.1.1.42;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-7268;MetaCyc: PWY-7124;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-6728	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-glutamine biosynthesis III";"Glutathione metabolism";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Ethylene biosynthesis V (engineered)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle"
XP_044251431.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016996878.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_017007687.2	8	KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism"
XP_016998427.2	5	Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695;Reactome: R-HSA-432722	"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis"
XP_017008011.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_016998947.2	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_017013584.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_017008269.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_017000620.2	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_044251719.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_017001927.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_017013437.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740	"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs"
XP_017013514.2	1	Reactome: R-HSA-3295583	"TRP channels"
XP_017000969.1	5	Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
XP_016995393.2	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_044251785.1	83	Reactome: R-HSA-74751;Reactome: R-HSA-179812;Reactome: R-HSA-5654733;Reactome: R-HSA-186763;Reactome: R-HSA-2179392;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-354194;Reactome: R-HSA-109704;Reactome: R-HSA-9034864;Reactome: R-HSA-8856825;Reactome: R-HSA-5654726;Reactome: R-HSA-8853334;Reactome: R-HSA-983695;Reactome: R-HSA-8853338;Reactome: R-HSA-5673001;Reactome: R-HSA-1433557;Reactome: R-HSA-8851907;Reactome: R-HSA-1839117;Reactome: R-HSA-5654699;Reactome: R-HSA-2428933;Reactome: R-HSA-912631;Reactome: R-HSA-9645135;Reactome: R-HSA-2029482;Reactome: R-HSA-5637810;Reactome: R-HSA-1295596;Reactome: R-HSA-1963640;Reactome: R-HSA-391160;Reactome: R-HSA-5654695;Reactome: R-HSA-9607240;Reactome: R-HSA-5654720;Reactome: R-HSA-8851805;Reactome: R-HSA-8983432;Reactome: R-HSA-5654693;Reactome: R-HSA-2424491;Reactome: R-HSA-5655302;Reactome: R-HSA-180292;Reactome: R-HSA-1963642;Reactome: R-HSA-912526;Reactome: R-HSA-9634285;Reactome: R-HSA-2871796;Reactome: R-HSA-5654706;Reactome: R-HSA-5655253;Reactome: R-HSA-5654727;Reactome: R-HSA-1236382;Reactome: R-HSA-6807004;Reactome: R-HSA-9028731;Reactome: R-HSA-5654700;Reactome: R-HSA-2730905;Reactome: R-HSA-375165;Reactome: R-HSA-8856828;Reactome: R-HSA-1250347;Reactome: R-HSA-2871809;Reactome: R-HSA-74749;Reactome: R-HSA-5654704;Reactome: R-HSA-1250196;Reactome: R-HSA-9028335;Reactome: R-HSA-2219530;Reactome: R-HSA-5654688;Reactome: R-HSA-5654689;Reactome: R-HSA-6811558;Reactome: R-HSA-389359;Reactome: R-HSA-512988;Reactome: R-HSA-210993;Reactome: R-HSA-167044;Reactome: R-HSA-5654712;Reactome: R-HSA-8875555;Reactome: R-HSA-9664565;Reactome: R-HSA-5663213;Reactome: R-HSA-5655291;Reactome: R-HSA-8853659;Reactome: R-HSA-8875656;Reactome: R-HSA-180336;Reactome: R-HSA-8865999;Reactome: R-HSA-9026519;Reactome: R-HSA-1257604;Reactome: R-HSA-5654719;Reactome: R-HSA-5654710;Reactome: R-HSA-5654732;Reactome: R-HSA-112412;Reactome: R-HSA-1433559;Reactome: R-HSA-9027284;Reactome: R-HSA-388841	"Insulin receptor signalling cascade";"GRB2 events in EGFR signaling";"Negative regulation of FGFR4 signaling";"Downstream signal transduction";"EGFR Transactivation by Gastrin";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"PI3K Cascade";"Activated NTRK3 signals through RAS";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of FGFR1 signaling";"Signaling by FGFR3 fusions in cancer";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Signaling by FGFR3 point mutants in cancer";"RAF/MAP kinase cascade";"Signaling by SCF-KIT";"MET activates PI3K/AKT signaling";"Signaling by cytosolic FGFR1 fusion mutants";"SHC-mediated cascade:FGFR2";"SHC-related events triggered by IGF1R";"Regulation of signaling by CBL";"STAT5 Activation";"Regulation of actin dynamics for phagocytic cup formation";"Constitutive Signaling by EGFRvIII";"Spry regulation of FGF signaling";"GRB2 events in ERBB2 signaling";"Signal regulatory protein family interactions";"PI-3K cascade:FGFR2";"FLT3 Signaling";"PI-3K cascade:FGFR4";"MET activates RAS signaling";"Interleukin-15 signaling";"FRS-mediated FGFR1 signaling";"DAP12 signaling";"Signaling by FGFR1 in disease";"GAB1 signalosome";"PI3K events in ERBB2 signaling";"Interleukin receptor SHC signaling";"Constitutive Signaling by Overexpressed ERBB2";"FCERI mediated MAPK activation";"FRS-mediated FGFR3 signaling";"Signaling by FGFR2 in disease";"Negative regulation of FGFR2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Negative regulation of MET activity";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR2 signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"NCAM signaling for neurite out-growth";"Clathrin-mediated endocytosis";"SHC1 events in ERBB4 signaling";"FCERI mediated Ca+2 mobilization";"Signal attenuation";"SHC-mediated cascade:FGFR3";"SHC1 events in ERBB2 signaling";"Activated NTRK2 signals through PI3K";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC-mediated cascade:FGFR1";"PI-3K cascade:FGFR1";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CD28 dependent Vav1 pathway";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Tie2 Signaling";"Signalling to RAS";"FRS-mediated FGFR4 signaling";"MET activates RAP1 and RAC1";"Signaling by ERBB2 KD Mutants";"RHO GTPases Activate WASPs and WAVEs";"Signaling by FGFR4 in disease";"RET signaling";"MET receptor recycling";"SHC1 events in EGFR signaling";"MET activates PTPN11";"Activated NTRK2 signals through RAS";"PIP3 activates AKT signaling";"SHC-mediated cascade:FGFR4";"PI-3K cascade:FGFR3";"Negative regulation of FGFR3 signaling";"SOS-mediated signalling";"Regulation of KIT signaling";"Erythropoietin activates RAS";"Costimulation by the CD28 family"
XP_016994523.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016997270.1	6	MetaCyc: PWY-5668;KEGG: 00564+2.7.8.5;MetaCyc: PWY-7817;Reactome: R-HSA-1483166;MetaCyc: PWY-5269;Reactome: R-HSA-1483148	"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PA";"Cardiolipin biosynthesis II";"Synthesis of PG"
XP_016996953.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6807878	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-mediated anterograde transport"
XP_044252173.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_017010711.2	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_016997976.2	5	Reactome: R-HSA-3371571;Reactome: R-HSA-198323;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5674400	"HSF1-dependent transactivation";"AKT phosphorylates targets in the cytosol";"mTOR signalling";"mTORC1-mediated signalling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_017006348.1	9	KEGG: 00564+1.1.1.94;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7385;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-7902;MetaCyc: PWY-7411;MetaCyc: PWY-6118	"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerol-3-phosphate shuttle"
XP_017003388.2	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_017003354.2	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_016999048.2	4	Reactome: R-HSA-6782315;MetaCyc: PWY-2781;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis";"Zeatin biosynthesis";"tRNA modification in the mitochondrion"
XP_017011161.2	12	Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8	"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"NrCAM interactions";"Synaptic adhesion-like molecules";"Purine metabolism"
XP_016992694.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017012250.2	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_017010154.2	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_017000839.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016996241.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_016994791.2	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_017010430.1	4	Reactome: R-HSA-1268020;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial protein import";"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_017002871.1	4	MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism"
XP_017013018.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_017006784.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_017005296.2	6	KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;MetaCyc: PWY-6363;MetaCyc: PWY-6364;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56	"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system"
XP_017012306.2	11	Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-68952;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-6782210;Reactome: R-HSA-174430;Reactome: R-HSA-6782135	"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"DNA replication initiation";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand synthesis initiation";"Dual incision in TC-NER"
XP_017007586.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5080	"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I"
XP_017012288.2	13	MetaCyc: PWY-5913;MetaCyc: PWY-7384;KEGG: 00720+4.2.1.2;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-7254;MetaCyc: PWY-8086;KEGG: 00020+4.2.1.2;Reactome: R-HSA-71403;KEGG: 00620+4.2.1.2;MetaCyc: PWY-561	"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_017003064.2	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_017000121.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_017009773.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_017005913.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017004199.2	16	Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-8853884	"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX"
XP_016996141.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017000513.2	20	MetaCyc: PWY-735;MetaCyc: PWY-7340;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7007;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-7854;MetaCyc: PWY-6837;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7606;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726	"Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"
XP_017004554.1	5	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_017006201.2	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_017004612.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_017009540.2	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_017004488.2	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_017006023.2	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_017011136.2	12	Reactome: R-HSA-447038;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-442982	"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Purine metabolism";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_017012985.2	1	MetaCyc: PWY-6938	"NADH repair"
XP_017002844.2	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_017012455.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_017013055.2	2	Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1	"Vitamin B1 (thiamin) metabolism";"Purine metabolism"
XP_044249620.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016994407.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017000504.2	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism"
XP_017015187.2	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_017011139.2	12	Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-451308	"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Synaptic adhesion-like molecules";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor"
XP_016994625.2	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_016997648.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016998689.2	14	MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis"
XP_044248647.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044249246.1	11	Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332	"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1"
XP_044248819.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_017000236.2	10	KEGG: 00010+2.7.1.11;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1861;MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484	"Glycolysis / Gluconeogenesis";"Methane metabolism";"Glycolysis";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_016993920.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_017015699.2	5	Reactome: R-HSA-983168;Reactome: R-HSA-977225;Reactome: R-HSA-5205685;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399	"Antigen processing: Ubiquitination & Proteasome degradation";"Amyloid fiber formation";"Pink/Parkin Mediated Mitophagy";"Josephin domain DUBs";"Aggrephagy"
XP_044248888.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_017015282.1	24	Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813	"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"HCMV Early Events";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"Recycling pathway of L1";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Gap junction assembly";"Kinesins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids"
XP_016996240.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_016996121.2	11	Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-72163;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-2173796;Reactome: R-HSA-350054	"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"mRNA Splicing - Major Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Notch-HLH transcription pathway"
XP_017009192.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044248663.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_017002379.2	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_017013448.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_016994781.2	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_017007376.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_016998843.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"Respiratory electron transport";"Mitochondrial protein import"
XP_017014164.2	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_017000181.2	3	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion"
XP_017006615.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_016994506.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016997937.2	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_017003383.2	4	Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_016998773.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_017012930.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_017004557.2	5	Reactome: R-HSA-211981;Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211945;Reactome: R-HSA-211976	"Xenobiotics";"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Phase I - Functionalization of compounds";"Endogenous sterols"
XP_017013591.2	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_044251877.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016997995.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_017012233.2	12	MetaCyc: PWY-5855;MetaCyc: PWY-5870;MetaCyc: PWY-5856;MetaCyc: PWY-5871;MetaCyc: PWY-5872;MetaCyc: PWY-5873;MetaCyc: PWY-6708;MetaCyc: PWY-5857;MetaCyc: PWY-7230;MetaCyc: PWY-7233;KEGG: 00130+1.14.99.60;Reactome: R-HSA-2142789	"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis"
XP_017011026.1	4	Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-381033	"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones"
XP_016999036.2	3	MetaCyc: PWY-0;KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117	"Putrescine degradation III";"Arginine and proline metabolism";"Spermine and spermidine degradation I"
XP_044251956.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_017013745.2	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_016993997.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_017000483.2	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_017006924.2	1	Reactome: R-HSA-264876	"Insulin processing"
XP_017005428.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_016997176.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017012418.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_017004807.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017013969.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_017012916.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016999426.2	6	KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;MetaCyc: PWY-622;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Digestion of dietary carbohydrate"
XP_017009868.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_017015144.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_016997105.2	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_017011759.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016999513.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-114516;Reactome: R-HSA-76005;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993	"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors"
XP_017015700.2	9	Reactome: R-HSA-446343;KEGG: 04150+2.7.11.1;Reactome: R-HSA-446353;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Localization of the PINCH-ILK-PARVIN complex to focal adhesions";"mTOR signaling pathway";"Cell-extracellular matrix interactions";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_017014862.2	5	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_044250354.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_017009531.2	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_017008654.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_017007769.2	10	Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206292	"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"HS-GAG degradation";"Galactose metabolism";"Neutrophil degranulation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"MPS VII - Sly syndrome"
XP_017014336.2	4	Reactome: R-HSA-176187;Reactome: R-HSA-111465;Reactome: R-HSA-5693607;Reactome: R-HSA-5689880	"Activation of ATR in response to replication stress";"Apoptotic cleavage of cellular proteins";"Processing of DNA double-strand break ends";"Ub-specific processing proteases"
XP_016998864.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_044251462.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_017007667.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_017001891.2	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_017012477.2	6	Reactome: R-HSA-71240;MetaCyc: PWY-5651;MetaCyc: PWY-7765;KEGG: 00380+1.14.13.9;MetaCyc: PWY-6309;MetaCyc: PWY-7717	"Tryptophan catabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis I"
XP_017006135.2	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_016995638.2	4	KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_017008736.2	8	Reactome: R-HSA-191273;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7524;MetaCyc: PWY-7391;MetaCyc: PWY-922	"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I"
XP_017009156.2	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_044248923.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_017007596.2	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_017015981.2	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_017011244.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_017008671.1	8	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-8953750;Reactome: R-HSA-912446	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Transcriptional Regulation by E2F6";"Meiotic recombination"
XP_017006462.2	3	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_017009809.2	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_044251445.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_017001227.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_017003721.2	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_017005297.2	6	MetaCyc: PWY-6363;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56	"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism"
XP_016997311.2	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_016995237.2	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_016998717.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044252209.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_017015968.2	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_016999110.1	52	Reactome: R-HSA-73863;Reactome: R-HSA-167243;Reactome: R-HSA-6782135;Reactome: R-HSA-167238;Reactome: R-HSA-72163;Reactome: R-HSA-6803529;Reactome: R-HSA-76066;Reactome: R-HSA-72203;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-5617472;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-6782210;Reactome: R-HSA-168325;Reactome: R-HSA-76071;Reactome: R-HSA-5250924;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-5578749;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-1834949;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-73772;Reactome: R-HSA-72165;Reactome: R-HSA-203927;Reactome: R-HSA-749476;Reactome: R-HSA-73762;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-76061;Reactome: R-HSA-75955;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Termination";"Tat-mediated HIV elongation arrest and recovery";"Dual incision in TC-NER";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Major Pathway";"FGFR2 alternative splicing";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Transcriptional regulation by small RNAs";"mRNA Capping";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"Cytosolic sensors of pathogen-associated DNA";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase I Promoter Escape";"mRNA Splicing - Minor Pathway";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression"
XP_017004891.2	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_044248821.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016996575.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_017014978.2	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_017007736.2	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_017000235.2	10	KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171	"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Glycolysis"
XP_016997521.2	9	Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome"
XP_017006762.2	56	Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-8939902	"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity"
XP_044251954.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_016993788.2	1	Reactome: R-HSA-428643	"Organic anion transporters"
XP_017011147.2	8	KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-438066	"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_017000573.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_044252214.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016995203.2	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_017016178.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044250814.1	3	KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Other glycan degradation"
XP_016995840.2	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_044248814.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016994172.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044248591.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017004148.2	4	MetaCyc: PWY-6281;Reactome: R-HSA-2408557;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_016997727.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
XP_017012012.2	4	KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250;Reactome: R-HSA-947581;Reactome: R-HSA-1362409	"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Molybdenum cofactor biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis"
XP_017000054.2	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_017014977.2	6	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;MetaCyc: PWY-6829;Reactome: R-HSA-6787450;MetaCyc: PWY-7285;MetaCyc: PWY-7286	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"Trna methylation (yeast)";"tRNA modification in the mitochondrion";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_016998977.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_017001838.2	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_017001887.2	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_017011813.2	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_016999911.2	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_017008271.2	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_017010018.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_017015811.2	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_017004307.2	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044250329.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_044249109.1	57	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-8854050	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_017012061.2	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_016997025.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044251846.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016997156.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016993229.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017013698.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044249368.1	6	Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_017000952.2	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_017000903.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016996243.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_017008080.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017002405.2	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_044251385.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_017005875.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044249753.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017010155.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_017006067.2	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_017010881.2	5	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-430039	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease"
XP_044248833.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_017004540.1	6	Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957	"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_016996741.2	6	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_017012926.2	7	Reactome: R-HSA-71064;Reactome: R-HSA-389661;KEGG: 00380+2.3.1.61;MetaCyc: PWY-5084;Reactome: R-HSA-71403;KEGG: 00020+2.3.1.61;KEGG: 00310+2.3.1.61	"Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Lysine degradation"
XP_017001925.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_044250331.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_017006404.2	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826	"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Hypoglycin biosynthesis"
XP_017015229.2	11	Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167200	"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_017008909.2	1	Reactome: R-HSA-525793	"Myogenesis"
XP_044249961.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_016999052.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016997274.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_044249963.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_017004773.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_017015873.2	5	Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_017009875.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_044250759.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017012186.2	5	MetaCyc: PWY-7159;MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7766	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)"
XP_017004412.2	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_017003549.2	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016996487.2	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_016992544.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017015776.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_044251248.1	12	Reactome: R-HSA-72662;Reactome: R-HSA-1169408;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-450408;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-429947;Reactome: R-HSA-9010553	"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"ISG15 antiviral mechanism";"mTORC1-mediated signalling";"Translation initiation complex formation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Deadenylation of mRNA";"Regulation of expression of SLITs and ROBOs"
XP_016997185.2	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_017011191.2	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_044251713.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-456926	"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_016995627.2	14	MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5972;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-8041	"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis"
XP_016994790.2	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_044249998.1	3	KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_016996207.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_017010836.2	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_017001282.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017012947.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017009174.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016992948.2	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_044250146.1	30	Reactome: R-HSA-1169091;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-1170546;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-2122947;Reactome: R-HSA-2644607;Reactome: R-HSA-5684264;Reactome: R-HSA-9604323;Reactome: R-HSA-917937;Reactome: R-HSA-5676590;Reactome: R-HSA-400253;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-69231;Reactome: R-HSA-2565942;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-180534	"Activation of NF-kappaB in B cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Prolactin receptor signaling";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"NOTCH1 Intracellular Domain Regulates Transcription";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Negative regulation of NOTCH4 signaling";"Iron uptake and transport";"NIK-->noncanonical NF-kB signaling";"Circadian Clock";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cyclin D associated events in G1";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4"
XP_017005514.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_017010871.2	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_017003107.2	6	Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors"
XP_044251579.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_016994670.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016996835.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956	"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_016999777.2	11	Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-418594	"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"G alpha (i) signalling events"
XP_044252245.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016997230.2	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_017000044.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016997223.2	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_017013829.2	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_044248853.1	5	Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-3134975;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619	"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN"
XP_017004623.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_017002841.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016998884.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_044250125.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016996140.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016996556.2	8	Reactome: R-HSA-6791461;KEGG: 00051+5.3.1.6;MetaCyc: PWY-1861;Reactome: R-HSA-5659996;Reactome: R-HSA-71336;KEGG: 00030+5.3.1.6;MetaCyc: PWY-5723;KEGG: 00710+5.3.1.6	"RPIA deficiency: failed conversion of RU5P to R5P";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"RPIA deficiency: failed conversion of R5P to RU5P";"Pentose phosphate pathway";"Pentose phosphate pathway";"Rubisco shunt";"Carbon fixation in photosynthetic organisms"
XP_017015865.2	3	MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE"
XP_017008616.2	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_017015004.2	14	Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-203927	"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis"
XP_017014580.1	25	Reactome: R-HSA-380270;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148	"Recruitment of mitotic centrosome proteins and complexes";"Kinesins";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Recycling pathway of L1";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044250803.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_017014442.2	14	Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725	"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_016994707.2	7	KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403;MetaCyc: PWY-8043;MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255;Reactome: R-HSA-5578999	"Glutathione metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_017007670.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_017005917.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044249407.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_017000434.2	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_017014452.2	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_017009246.1	4	Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48	"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_016993809.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-191859	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly"
XP_016996213.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044248690.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_017005473.2	3	KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347	"Methane metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis"
XP_016997022.2	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_017009972.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016997224.2	1	Reactome: R-HSA-419771	"Opsins"
XP_017012911.2	10	MetaCyc: PWY-7559;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2	"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Glutathione metabolism";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism"
XP_017012148.2	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_017001724.2	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_017012417.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_017005677.2	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_044251667.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_017005278.1	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
XP_017015021.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_017002906.2	3	KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662	"Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_016998536.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_017015954.1	7	Reactome: R-HSA-114608;Reactome: R-HSA-381033;Reactome: R-HSA-381183;Reactome: R-HSA-3371453;Reactome: R-HSA-381042;Reactome: R-HSA-983170;Reactome: R-HSA-381070	"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperones";"ATF6 (ATF6-alpha) activates chaperone genes";"Regulation of HSF1-mediated heat shock response";"PERK regulates gene expression";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"IRE1alpha activates chaperones"
XP_017002690.1	52	Reactome: R-HSA-8851708;Reactome: R-HSA-73779;Reactome: R-HSA-73762;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-167162;Reactome: R-HSA-76061;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-167172;Reactome: R-HSA-5578749;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-1834949;Reactome: R-HSA-72086;Reactome: R-HSA-5601884;Reactome: R-HSA-72165;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-203927;Reactome: R-HSA-749476;Reactome: R-HSA-6782210;Reactome: R-HSA-168325;Reactome: R-HSA-76071;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-5250924;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-6803529;Reactome: R-HSA-6782135;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-73863;Reactome: R-HSA-72163;Reactome: R-HSA-76066;Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-5617472	"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Transcription of the HIV genome";"Transcriptional regulation by small RNAs";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"Cytosolic sensors of pathogen-associated DNA";"mRNA Capping";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Minor Pathway";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Abortive And Retractive Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"FGFR2 alternative splicing";"Dual incision in TC-NER";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Transcription Termination";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_017010243.2	19	MetaCyc: PWY-6969;MetaCyc: PWY-7384;MetaCyc: PWY-5538;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;Reactome: R-HSA-6798695;MetaCyc: PWY-5172;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;Reactome: R-HSA-75105;KEGG: 00020+2.3.3.8;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5;KEGG: 00720+2.3.3.8;Reactome: R-HSA-163765;Reactome: R-HSA-71403	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Neutrophil degranulation";"Acetyl-coa biosynthesis III (from citrate)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Propanoate metabolism";"Fatty acyl-CoA biosynthesis";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Citric acid cycle (TCA cycle)"
XP_017003564.2	3	Reactome: R-HSA-8878166;Reactome: R-HSA-6785807;Reactome: R-HSA-8939902	"Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity"
XP_044249981.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-110357	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Displacement of DNA glycosylase by APEX1"
XP_017005477.1	8	Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-381676	"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_017000443.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044250462.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_017011006.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257	"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion"
XP_016993754.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_016994006.2	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
XP_016999441.1	6	MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;MetaCyc: PWY-622;Reactome: R-HSA-189085	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Digestion of dietary carbohydrate"
XP_017002412.2	3	MetaCyc: PWY-5698;MetaCyc: PWY-5697;KEGG: 00230+3.5.2.5	"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism"
XP_016997512.2	8	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540	"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Activation of RAC1"
XP_017006957.2	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044251921.1	10	Reactome: R-HSA-400206;Reactome: R-HSA-9022538;Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-9022702;Reactome: R-HSA-9022699;Reactome: R-HSA-9022692;Reactome: R-HSA-983231;Reactome: R-HSA-3899300;Reactome: R-HSA-9615017	"Regulation of lipid metabolism by PPARalpha";"Loss of MECP2 binding ability to 5mC-DNA";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands";"MECP2 regulates neuronal receptors and channels";"Regulation of MECP2 expression and activity";"Factors involved in megakaryocyte development and platelet production";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_017008545.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_017015715.2	9	MetaCyc: PWY-5663;MetaCyc: PWY-7852;MetaCyc: PWY-6147;MetaCyc: PWY-5664;MetaCyc: PWY-6983;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6703	"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"Preq0 biosynthesis"
XP_017011762.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_017004654.2	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044251222.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_016994207.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_017014870.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016997122.2	5	Reactome: R-HSA-199220;MetaCyc: PWY-6289;MetaCyc: PWY-6012;KEGG: 00770+2.7.8.7;MetaCyc: PWY-6012-1	"Vitamin B5 (pantothenate) metabolism";"Petrobactin biosynthesis";"Acyl carrier protein metabolism";"Pantothenate and CoA biosynthesis";"Acyl carrier protein activation"
XP_017001882.2	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_044251937.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_017009517.2	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_017001984.2	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_017010696.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016999716.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016999948.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017009238.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016995175.1	6	MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis"
XP_017003993.2	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_017014956.2	4	Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-6802952	"Macroautophagy";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions"
XP_017010786.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_017014631.2	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_017014405.2	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_017010475.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_017013149.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016998927.2	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_017009588.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017013159.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016996232.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_044250645.1	5	MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013	"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III"
XP_044251664.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_017009108.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_044251361.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_017000996.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044249787.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044250415.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-68884;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"MHC class II antigen presentation";"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044249312.1	5	Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32;KEGG: 00620+4.1.1.32;KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383	"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_017015634.2	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_017007474.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_017000868.2	5	MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate"
XP_016997199.2	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_017000447.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_017015523.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017000675.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_017014481.2	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_016992380.2	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_016995232.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044249177.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_044248827.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_016996067.2	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_044252045.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_017009241.2	3	Reactome: R-HSA-9029569;Reactome: R-HSA-8964058;Reactome: R-HSA-1369062	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling";"ABC transporters in lipid homeostasis"
XP_016997822.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044249168.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_017014252.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044251776.1	7	Reactome: R-HSA-210500;Reactome: R-HSA-5628897;MetaCyc: PWY-5921;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2	"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis"
XP_016996570.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016995063.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017014172.2	3	MetaCyc: PWY-7424;KEGG: 00100+2.3.1.26;Reactome: R-HSA-8964038	"Sterol:steryl ester interconversion (yeast)";"Steroid biosynthesis";"LDL clearance"
XP_017012296.1	42	Reactome: R-HSA-3214841;Reactome: R-HSA-8939236;Reactome: R-HSA-427389;Reactome: R-HSA-912446;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-5693607;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-8936459;Reactome: R-HSA-171306;Reactome: R-HSA-2559586;Reactome: R-HSA-977225;Reactome: R-HSA-1221632;Reactome: R-HSA-9610379;Reactome: R-HSA-5625886;Reactome: R-HSA-110329;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-3214842;Reactome: R-HSA-1912408;Reactome: R-HSA-5693571;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-69473;Reactome: R-HSA-3214858;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-5693565	"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic recombination";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"Processing of DNA double-strand break ends";"DNA methylation";"Estrogen-dependent gene expression";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Packaging Of Telomere Ends";"DNA Damage/Telomere Stress Induced Senescence";"Amyloid fiber formation";"Meiotic synapsis";"HCMV Late Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Cleavage of the damaged pyrimidine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDMs demethylate histones";"Pre-NOTCH Transcription and Translation";"Nonhomologous End-Joining (NHEJ)";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"G2/M DNA damage checkpoint";"RMTs methylate histone arginines";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_017012278.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017003398.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_017003895.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-2408557	"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_017014930.2	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic"
XP_016999029.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_017002250.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_017014302.1	5	Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6814122	"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_044250020.1	15	MetaCyc: PWY-6886;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-6142;KEGG: 00620+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-5723;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-7383;MetaCyc: PWY-1042;MetaCyc: PWY-7218	"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"Purine metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)"
XP_017012000.2	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_016997168.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_017009371.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_017000232.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-75035	"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_017002658.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription"
XP_017010300.2	1	Reactome: R-HSA-5676934	"Protein repair"
XP_017011203.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_017007477.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_017011750.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_017002859.2	3	Reactome: R-HSA-392517;Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"Rap1 signalling";"cGMP effects";"Ca2+ pathway"
XP_017016286.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017000380.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_017010057.2	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_016997341.2	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_017007571.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044251319.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_016995489.2	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_017011335.1	10	KEGG: 00520+5.1.3.2;MetaCyc: PWY-7328;Reactome: R-HSA-5609977;MetaCyc: PWY-6527;MetaCyc: PWY-6317;Reactome: R-HSA-70370;MetaCyc: PWY-3821;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6397	"Amino sugar and nucleotide sugar metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"
XP_017007688.2	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_017010802.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017000311.2	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_016995309.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_017006938.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_017003785.2	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_044249188.1	8	Reactome: R-HSA-380270;Reactome: R-HSA-5689880;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"Ub-specific processing proteases";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_017008759.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044252130.1	9	KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-8052;MetaCyc: PWY-6351;Reactome: R-HSA-112043;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039	"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule"
XP_017008520.2	6	MetaCyc: PWY-7391;KEGG: 00900+2.7.1.36;MetaCyc: PWY-922;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-6174	"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)"
XP_017009180.2	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_016998695.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044250210.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_017003362.2	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_016999231.2	20	MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7858;MetaCyc: PWY-7574;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7007;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-735;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136	"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_017012433.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_017001795.1	23	Reactome: R-HSA-418594;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-400042;Reactome: R-HSA-4086398;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-6814122;Reactome: R-HSA-432040;Reactome: R-HSA-202040;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-418597;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-418217;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-420092;Reactome: R-HSA-8964616	"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"Adrenaline,noradrenaline inhibits insulin secretion";"Ca2+ pathway";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Vasopressin regulates renal water homeostasis via Aquaporins";"G-protein activation";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"G alpha (z) signalling events";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"Glucagon-type ligand receptors";"G beta:gamma signalling through CDC42"
XP_017006529.1	27	Reactome: R-HSA-198323;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-3371453;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5610785;Reactome: R-HSA-5467337;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5250924;Reactome: R-HSA-5674400;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-75815;KEGG: 05170+2.7.11.1;Reactome: R-HSA-399956;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;KEGG: 05165+2.7.11.1	"AKT phosphorylates targets in the cytosol";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"Regulation of HSF1-mediated heat shock response";"Thermogenesis";"Relaxin signaling pathway";"GLI3 is processed to GLI3R by the proteasome";"APC truncation mutants have impaired AXIN binding";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"mTOR signaling pathway";"Human cytomegalovirus infection";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by AKT1 E17K in Cancer";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Human immunodeficiency virus 1 infection";"CRMPs in Sema3A signaling";"PI3K-Akt signaling pathway";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Human papillomavirus infection"
XP_016999642.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_017001466.2	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_017003729.2	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_017012726.2	14	MetaCyc: PWY-8053;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634	"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Retinoid metabolism and transport"
XP_044248745.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017007920.1	57	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-8854050;Reactome: R-HSA-180585	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Separation of Sister Chromatids";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G"
XP_017001806.2	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_044249002.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_044250169.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_017015199.2	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_044251495.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_017015818.2	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_016998849.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_017006648.2	3	Reactome: R-HSA-1362409;KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020	"Mitochondrial iron-sulfur cluster biogenesis";"Porphyrin and chlorophyll metabolism";"Mitochondrial protein import"
XP_017011104.2	4	Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_017004605.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_017004094.2	4	MetaCyc: PWY-6834;KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202;KEGG: 00270+4.1.1.50	"Spermidine biosynthesis III";"Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism"
XP_017001454.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_016997865.2	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_017012169.2	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_016994675.2	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_017004353.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016996406.2	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_017007318.2	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_017009874.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_016999084.2	2	Reactome: R-HSA-110314;Reactome: R-HSA-6783310	"Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway"
XP_017005587.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017004919.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits"
XP_016993409.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_017009342.2	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_017009084.2	14	MetaCyc: PWY-2161;MetaCyc: PWY-2201;MetaCyc: PWY-3661;KEGG: 00680+2.1.2.1;MetaCyc: PWY-5497;Reactome: R-HSA-196757;MetaCyc: PWY-181;KEGG: 00260+2.1.2.1;KEGG: 00670+2.1.2.1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-3661-1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3841	"Folate polyglutamylation";"Folate transformations I";"Glycine betaine degradation I";"Methane metabolism";"Purine nucleobases degradation II (anaerobic)";"Metabolism of folate and pterines";"Photorespiration ";"Glycine, serine and threonine metabolism";"One carbon pool by folate";"Cyanoamino acid metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycine betaine degradation II (mammalian)";"Glyoxylate and dicarboxylate metabolism";"Folate transformations II (plants)"
XP_017015590.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016997488.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016993397.2	5	Reactome: R-HSA-389661;MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88;Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88	"Glyoxylate metabolism and glycine degradation";"Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism";"Proline catabolism";"Arginine and proline metabolism"
XP_017004560.1	4	MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5041	"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"Methylation";"S-adenosyl-L-methionine cycle II"
XP_016999080.2	3	MetaCyc: PWY-5067;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch and sucrose metabolism"
XP_016996523.2	27	Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453	"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response"
XP_016995375.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662	"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling"
XP_017009152.2	4	MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;Reactome: R-HSA-70688	"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism"
XP_016997383.2	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_017006314.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_017004621.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016996270.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_017004563.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016998533.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_017002947.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_017003703.1	13	Reactome: R-HSA-437239;Reactome: R-HSA-5140745;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-177504;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-167590	"Recycling pathway of L1";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation"
XP_017003154.2	7	Reactome: R-HSA-73817;MetaCyc: PWY-6277;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121;MetaCyc: PWY-7282	"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_016993376.2	18	Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4	"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism"
XP_016998878.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_017015189.2	10	MetaCyc: PWY-5849;MetaCyc: PWY-7996;MetaCyc: PWY-5844;Reactome: R-HSA-2142789;MetaCyc: PWY-5839;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5890;MetaCyc: PWY-5895;MetaCyc: PWY-5892;MetaCyc: PWY-5891	"Menaquinol-6 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-9 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-7 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-11 biosynthesis"
XP_017010435.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_017001017.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_016995557.2	6	Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;Reactome: R-HSA-6798695	"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Tryptophan metabolism";"Neutrophil degranulation"
XP_044252212.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_017010633.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_017016148.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656	"Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling"
XP_017014543.2	7	MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7	"Justicidin B biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis"
XP_017010311.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044250969.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_017000899.2	2	MetaCyc: PWY-5381;KEGG: 00760+2.7.1.173+2.7.1.22	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_016998917.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_017007726.2	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_044249971.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_016997920.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_017015896.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016993398.2	3	Reactome: R-HSA-6783984;KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"Glycine degradation";"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_044250174.1	22	Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-5675221;Reactome: R-HSA-432142;Reactome: R-HSA-9648025;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-6811558;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-5673000;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-389513	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"Negative regulation of MAPK pathway";"Platelet sensitization by LDL";"EML4 and NUDC in mitotic spindle formation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling"
XP_016997873.1	3	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism"
XP_044251749.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_016994991.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_017007017.1	6	KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-1268020;Reactome: R-HSA-71403;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3	"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Mitochondrial protein import";"Citric acid cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)"
XP_044251360.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_017012949.2	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_017016142.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017008772.2	2	Reactome: R-HSA-429958;Reactome: R-HSA-390471	"mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis"
XP_017003795.2	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_017007871.1	11	Reactome: R-HSA-3000170;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332	"Syndecan interactions";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1"
XP_017005556.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_017001777.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044250872.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017009568.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902	"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation"
XP_016999655.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_017010959.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044249760.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_016994786.2	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_016992391.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016993713.2	27	Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-6784531	"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"HCMV Late Events";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus"
XP_016998693.2	4	KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation"
XP_017008704.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Translation initiation complex formation";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_017002449.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_017010177.2	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_044249625.1	42	Reactome: R-HSA-9610379;Reactome: R-HSA-110329;Reactome: R-HSA-5625886;Reactome: R-HSA-977225;Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-3214842;Reactome: R-HSA-1912408;Reactome: R-HSA-5693571;Reactome: R-HSA-201722;Reactome: R-HSA-3214815;Reactome: R-HSA-3214858;Reactome: R-HSA-69473;Reactome: R-HSA-2299718;Reactome: R-HSA-5250924;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-110328;Reactome: R-HSA-3214841;Reactome: R-HSA-8939236;Reactome: R-HSA-912446;Reactome: R-HSA-427389;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-5693607;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-9616222;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-171306	"HCMV Late Events";"Cleavage of the damaged pyrimidine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Amyloid fiber formation";"Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDMs demethylate histones";"Pre-NOTCH Transcription and Translation";"Nonhomologous End-Joining (NHEJ)";"Formation of the beta-catenin:TCF transactivating complex";"HDACs deacetylate histones";"RMTs methylate histone arginines";"G2/M DNA damage checkpoint";"Condensation of Prophase Chromosomes";"B-WICH complex positively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Meiotic recombination";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"Processing of DNA double-strand break ends";"Estrogen-dependent gene expression";"DNA methylation";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"PRC2 methylates histones and DNA";"Transcriptional regulation of granulopoiesis";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Packaging Of Telomere Ends"
XP_017010594.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_017007864.2	11	Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-3000170;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237	"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"Syndecan interactions";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2"
XP_016992396.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016998911.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_017000040.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
XP_017002995.2	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016997295.2	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_016999147.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017014397.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016997616.2	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_016997619.1	18	Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis"
XP_017010791.2	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_017012444.2	16	Reactome: R-HSA-1251985;Reactome: R-HSA-5673001;Reactome: R-HSA-1963642;Reactome: R-HSA-1257604;Reactome: R-HSA-1250347;Reactome: R-HSA-1236394;Reactome: R-HSA-8847993;Reactome: R-HSA-8863795;Reactome: R-HSA-1250342;Reactome: R-HSA-1250196;Reactome: R-HSA-1963640;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1227986;Reactome: R-HSA-6785631;Reactome: R-HSA-9664565	"Nuclear signaling by ERBB4";"RAF/MAP kinase cascade";"PI3K events in ERBB2 signaling";"PIP3 activates AKT signaling";"SHC1 events in ERBB4 signaling";"Signaling by ERBB4";"ERBB2 Activates PTK6 Signaling";"Downregulation of ERBB2 signaling";"PI3K events in ERBB4 signaling";"SHC1 events in ERBB2 signaling";"GRB2 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2 KD Mutants"
XP_016999121.2	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_016996476.2	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_017000518.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016996088.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016995157.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_016997959.2	40	KEGG: 00640+4.2.1.17;MetaCyc: PWY-5177;MetaCyc: PWY-7216;MetaCyc: PWY-5136;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7094;MetaCyc: PWY-7656;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-6583;MetaCyc: PWY-5138;MetaCyc: PWY-6944;MetaCyc: PWY-6945;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-6883;MetaCyc: PWY-7654;MetaCyc: PWY-6946;MetaCyc: PWY-1361;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-7007;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-5109;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35	"Propanoate metabolism";"Glutaryl-coa degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Aminobenzoate degradation";"Fatty acid salvage";"Spodoptera littoralis pheromone biosynthesis";"Butanoate metabolism";"beta-Alanine metabolism";"Carbon fixation pathways in prokaryotes";"Methyl tert-butyl ether degradation";"Pyruvate fermentation to butanol I";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Androstenedione degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Valine, leucine and isoleucine degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Pyruvate fermentation to butanol II (engineered)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Benzoyl-coa degradation I (aerobic)";"Lysine degradation";"Caprolactam degradation";"Limonene and pinene degradation";"Toluene degradation";"2-methylpropene degradation";"Methyl ketone biosynthesis (engineered)";"Geraniol degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Benzoate degradation";"Tryptophan metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to hexanol (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fermentation to 2-methylbutanoate";"Fatty acid degradation";"Phenylalanine metabolism";"Fatty acid elongation"
XP_017000425.2	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_017006443.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016993223.2	4	Reactome: R-HSA-77289;Reactome: R-HSA-6799198;Reactome: R-HSA-389661;Reactome: R-HSA-611105	"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport"
XP_044249929.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_016999530.2	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_044248698.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017008006.2	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_017015951.2	4	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546;Reactome: R-HSA-8849175	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism"
XP_016999963.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017001114.2	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_017008899.1	17	Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_044249859.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017010602.2	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_017007475.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016996866.2	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_016997161.1	21	KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;KEGG: 00230+2.7.4.6+2.7.4.3;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7226;MetaCyc: PWY-7176;MetaCyc: PWY-7197;MetaCyc: PWY-7205;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7187;MetaCyc: PWY-7227;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7219;MetaCyc: PWY-7221;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7220	"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine metabolism";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"CMP phosphorylation";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II"
XP_016993301.2	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_017003687.2	17	Reactome: R-HSA-4086398;Reactome: R-HSA-450321;Reactome: R-HSA-5357956;Reactome: R-HSA-450302;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-975163;Reactome: R-HSA-9014325;Reactome: R-HSA-5607764;Reactome: R-HSA-937072;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-168638;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-937042;Reactome: R-HSA-1169091	"Ca2+ pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TNFR1-induced NFkappaB signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Ub-specific processing proteases";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"CLEC7A (Dectin-1) signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"NOD1/2 Signaling Pathway";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"IRAK2 mediated activation of TAK1 complex";"Activation of NF-kappaB in B cells"
XP_017011695.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_017015429.2	3	Reactome: R-HSA-416476;Reactome: R-HSA-881907;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Gastrin-CREB signalling pathway via PKC and MAPK";"Peptide ligand-binding receptors"
XP_044250229.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016999149.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017004485.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_017015361.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_017011314.2	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_017009858.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017011803.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_017002948.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_044251878.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044249232.1	56	Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-5668541	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Degradation of AXIN";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway"
XP_016995935.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_017015132.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_017016126.2	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism"
XP_017011685.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016992769.2	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_017010458.2	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_017013708.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017005331.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_017002608.2	6	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway"
XP_017006656.2	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_017002591.2	15	MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-5723;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-1042;MetaCyc: PWY-7218	"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Rubisco shunt";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)"
XP_016999788.2	1	Reactome: R-HSA-419771	"Opsins"
XP_016999317.2	4	MetaCyc: PWY-7285;MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6782315	"Methylwyosine biosynthesis";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol"
XP_017012142.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044251386.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_017014962.2	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_017004936.2	14	Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167290	"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation"
XP_044251808.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017013142.2	3	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_044250069.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-5466	"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis"
XP_017000400.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_017015522.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017004600.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_017009245.1	4	Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48	"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_017005077.1	32	Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-6803529;Reactome: R-HSA-72203;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-167152	"Formation of RNA Pol II elongation complex";"mRNA Capping";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"FGFR2 alternative splicing";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_017000267.1	6	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-5632684	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"Hedgehog 'on' state"
XP_016999091.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044250842.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044250154.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_016994528.1	2	Reactome: R-HSA-8875656;Reactome: R-HSA-8873719	"MET receptor recycling";"RAB geranylgeranylation"
XP_016996063.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_017008283.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016998869.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016996393.1	7	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-373753	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Nephrin family interactions"
XP_016993765.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_017007834.2	11	Reactome: R-HSA-1250196;Reactome: R-HSA-6785631;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-1963642;Reactome: R-HSA-1257604;Reactome: R-HSA-1227986;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530	"SHC1 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB2 signaling";"PIP3 activates AKT signaling";"Signaling by ERBB2";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer"
XP_017005476.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-164378	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling"
XP_044249473.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_017011889.2	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_017013603.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-6784531	"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus"
XP_017012785.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016994740.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016994696.2	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_017010632.2	6	Reactome: R-HSA-173599;KEGG: 00520+1.1.1.22;KEGG: 00053+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7346	"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Ascorbate and aldarate metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"Pentose and glucuronate interconversions";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)"
XP_017015767.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016997523.2	9	Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167162	"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape"
XP_017001110.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_017015148.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_017001131.2	2	Reactome: R-HSA-1237044;KEGG: 00520+1.6.2.2	"Erythrocytes take up carbon dioxide and release oxygen";"Amino sugar and nucleotide sugar metabolism"
XP_017010178.1	6	MetaCyc: PWY-4261;MetaCyc: PWY-6118;MetaCyc: PWY-6952;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560	"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Synthesis of PA";"Glycerophospholipid metabolism";"Triglyceride catabolism"
XP_017001391.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_017001869.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_016994692.2	4	Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-2129379	"ECM proteoglycans";"Syndecan interactions";"Integrin cell surface interactions";"Molecules associated with elastic fibres"
XP_016992626.2	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_044248609.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_016998853.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016992669.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_017009002.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017004681.1	6	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1"
XP_016997478.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016998760.2	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_017006837.2	5	MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_016996831.1	4	KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.4	"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_044249827.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016993366.2	7	KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-70268;Reactome: R-HSA-204174	"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_017015238.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_016998863.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_017007679.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044249252.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_017004312.1	14	MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis"
XP_016994124.2	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_017007550.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_017001113.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_016997180.2	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_017012173.2	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_044248610.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_016999511.1	6	Reactome: R-HSA-76005;Reactome: R-HSA-418597;Reactome: R-HSA-114516;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900	"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4"
XP_017007993.2	4	Reactome: R-HSA-8866427;MetaCyc: PWY-7511;Reactome: R-HSA-9031525;Reactome: R-HSA-983168	"VLDLR internalisation and degradation";"Protein ubiquitination";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044250433.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_017001788.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016996750.2	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_016994396.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_017015002.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_017015945.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044248506.1	5	Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Protein ubiquitination";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_017010974.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_044249057.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_017008333.2	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_017010668.1	8	MetaCyc: PWY-8086;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00640+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00270+1.1.1.27	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate";"Propanoate metabolism";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Cysteine and methionine metabolism"
XP_044251783.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_044251568.1	3	KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403	"Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling"
XP_016999134.2	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_017000275.2	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_016998925.2	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_016992351.2	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_044251832.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016999220.2	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_017011182.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016995624.2	14	MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-8041	"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis"
XP_016994750.2	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_044250309.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape"
XP_044250845.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_044251826.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044249284.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016996614.2	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_044250662.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044251097.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_016999232.2	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_016997189.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_017000051.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_016993432.2	2	Reactome: R-HSA-5689880;MetaCyc: PWY-7511	"Ub-specific processing proteases";"Protein ubiquitination"
XP_017009177.2	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_017005029.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_016999838.2	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_017000411.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"Triglyceride catabolism";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_016995544.2	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_017004082.2	3	Reactome: R-HSA-4724289;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.267	"Defective ALG6 causes ALG6-CDG (CDG-1c)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_016995653.2	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_016995697.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_017008142.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_017002203.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044250016.1	4	KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)"
XP_017003679.2	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_017013821.2	7	KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1	"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)"
XP_044250342.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_017001069.2	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016992816.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Translation initiation complex formation";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_017013673.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017014557.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_017005980.2	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_016992510.2	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_017016036.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-9609523;Reactome: R-HSA-1660661	"Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Sphingolipid de novo biosynthesis"
XP_017010788.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_017012590.2	3	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-111367	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs"
XP_017005943.2	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_017006391.2	12	Reactome: R-HSA-71240;MetaCyc: PWY-7901;MetaCyc: PWY-1187;MetaCyc: PWY-2821;MetaCyc: PWY-6936;MetaCyc: PWY-6309;KEGG: 00380+2.6.1.7;KEGG: 00270+4.4.1.13;MetaCyc: PWY-801;MetaCyc: PWY-601;MetaCyc: PWY-6842;KEGG: 00450+4.4.1.13	"Tryptophan catabolism";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tryptophan";"Glutathione-mediated detoxification II";"Selenocompound metabolism"
XP_017007161.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044249138.1	23	Reactome: R-HSA-432040;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-4086398;Reactome: R-HSA-500657;Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-418592;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-8964616;Reactome: R-HSA-420092;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-418217;Reactome: R-HSA-418555;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-416482;Reactome: R-HSA-418597;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-202040	"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Ca2+ pathway";"Presynaptic function of Kainate receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 1";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"G beta:gamma signalling through CDC42";"Glucagon-type ligand receptors";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta";"G alpha (s) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (12/13) signalling events";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"G-protein activation"
XP_016998235.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017012419.2	3	KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317	"Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)"
XP_044252083.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_044249165.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_044249337.1	2	Reactome: R-HSA-204626;MetaCyc: PWY-5905	"Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis"
XP_017005730.2	12	Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-381038;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-3371497;Reactome: R-HSA-380270	"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"XBP1(S) activates chaperone genes";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes"
XP_017012328.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017009341.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016999498.2	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_017005396.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_044250306.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167161	"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation"
XP_016993126.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017007989.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016999903.2	4	KEGG: 00590+5.3.99.3;Reactome: R-HSA-499943;Reactome: R-HSA-6798695;Reactome: R-HSA-2162123	"Arachidonic acid metabolism";"Interconversion of nucleotide di- and triphosphates";"Neutrophil degranulation";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"
XP_017006436.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_016999462.2	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_017005770.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_017000273.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_044251669.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017005968.2	6	Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_017005190.2	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_017005213.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016995333.2	16	Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-176407;Reactome: R-HSA-174184	"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_017011568.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016996711.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044249088.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_016997486.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017005724.2	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_016995218.2	5	Reactome: R-HSA-6811434;Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295	"COPI-dependent Golgi-to-ER retrograde traffic";"Intraflagellar transport";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation"
XP_017001019.1	83	Reactome: R-HSA-9028335;Reactome: R-HSA-1250196;Reactome: R-HSA-5654704;Reactome: R-HSA-74749;Reactome: R-HSA-2871809;Reactome: R-HSA-1250347;Reactome: R-HSA-8856828;Reactome: R-HSA-375165;Reactome: R-HSA-5654700;Reactome: R-HSA-2730905;Reactome: R-HSA-9028731;Reactome: R-HSA-6807004;Reactome: R-HSA-1236382;Reactome: R-HSA-5654727;Reactome: R-HSA-5655253;Reactome: R-HSA-5654706;Reactome: R-HSA-388841;Reactome: R-HSA-9027284;Reactome: R-HSA-1433559;Reactome: R-HSA-112412;Reactome: R-HSA-5654732;Reactome: R-HSA-5654719;Reactome: R-HSA-5654710;Reactome: R-HSA-1257604;Reactome: R-HSA-9026519;Reactome: R-HSA-8865999;Reactome: R-HSA-180336;Reactome: R-HSA-8875656;Reactome: R-HSA-8853659;Reactome: R-HSA-5655291;Reactome: R-HSA-5663213;Reactome: R-HSA-9664565;Reactome: R-HSA-8875555;Reactome: R-HSA-5654712;Reactome: R-HSA-167044;Reactome: R-HSA-512988;Reactome: R-HSA-210993;Reactome: R-HSA-389359;Reactome: R-HSA-6811558;Reactome: R-HSA-5654689;Reactome: R-HSA-5654688;Reactome: R-HSA-2219530;Reactome: R-HSA-1963640;Reactome: R-HSA-1295596;Reactome: R-HSA-5637810;Reactome: R-HSA-2029482;Reactome: R-HSA-9645135;Reactome: R-HSA-912631;Reactome: R-HSA-2428933;Reactome: R-HSA-5654699;Reactome: R-HSA-1839117;Reactome: R-HSA-8851907;Reactome: R-HSA-5673001;Reactome: R-HSA-1433557;Reactome: R-HSA-8853334;Reactome: R-HSA-983695;Reactome: R-HSA-8853338;Reactome: R-HSA-5654726;Reactome: R-HSA-8856825;Reactome: R-HSA-9034864;Reactome: R-HSA-109704;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-354194;Reactome: R-HSA-2179392;Reactome: R-HSA-186763;Reactome: R-HSA-5654733;Reactome: R-HSA-179812;Reactome: R-HSA-74751;Reactome: R-HSA-2871796;Reactome: R-HSA-9634285;Reactome: R-HSA-912526;Reactome: R-HSA-180292;Reactome: R-HSA-5655302;Reactome: R-HSA-1963642;Reactome: R-HSA-2424491;Reactome: R-HSA-5654693;Reactome: R-HSA-8983432;Reactome: R-HSA-8851805;Reactome: R-HSA-5654720;Reactome: R-HSA-9607240;Reactome: R-HSA-5654695;Reactome: R-HSA-391160	"Activated NTRK2 signals through PI3K";"SHC1 events in ERBB2 signaling";"SHC-mediated cascade:FGFR3";"Signal attenuation";"FCERI mediated Ca+2 mobilization";"SHC1 events in ERBB4 signaling";"Clathrin-mediated endocytosis";"NCAM signaling for neurite out-growth";"FRS-mediated FGFR2 signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Activated NTRK2 signals through FRS2 and FRS3";"Negative regulation of MET activity";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Negative regulation of FGFR2 signaling";"Signaling by FGFR2 in disease";"FRS-mediated FGFR3 signaling";"Costimulation by the CD28 family";"Erythropoietin activates RAS";"Regulation of KIT signaling";"SOS-mediated signalling";"Negative regulation of FGFR3 signaling";"SHC-mediated cascade:FGFR4";"PI-3K cascade:FGFR3";"PIP3 activates AKT signaling";"Activated NTRK2 signals through RAS";"MET activates PTPN11";"SHC1 events in EGFR signaling";"MET receptor recycling";"RET signaling";"Signaling by FGFR4 in disease";"RHO GTPases Activate WASPs and WAVEs";"Signaling by ERBB2 KD Mutants";"MET activates RAP1 and RAC1";"FRS-mediated FGFR4 signaling";"Signalling to RAS";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Tie2 Signaling";"CD28 dependent Vav1 pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI-3K cascade:FGFR1";"SHC-mediated cascade:FGFR1";"Constitutive Signaling by Aberrant PI3K in Cancer";"GRB2 events in ERBB2 signaling";"Spry regulation of FGF signaling";"Constitutive Signaling by EGFRvIII";"Regulation of actin dynamics for phagocytic cup formation";"STAT5 Activation";"Regulation of signaling by CBL";"SHC-related events triggered by IGF1R";"SHC-mediated cascade:FGFR2";"Signaling by cytosolic FGFR1 fusion mutants";"MET activates PI3K/AKT signaling";"RAF/MAP kinase cascade";"Signaling by SCF-KIT";"Signaling by FGFR3 fusions in cancer";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Signaling by FGFR3 point mutants in cancer";"Negative regulation of FGFR1 signaling";"Cargo recognition for clathrin-mediated endocytosis";"Activated NTRK3 signals through RAS";"PI3K Cascade";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"EGFR Transactivation by Gastrin";"Downstream signal transduction";"Negative regulation of FGFR4 signaling";"GRB2 events in EGFR signaling";"Insulin receptor signalling cascade";"FCERI mediated MAPK activation";"Constitutive Signaling by Overexpressed ERBB2";"Interleukin receptor SHC signaling";"GAB1 signalosome";"Signaling by FGFR1 in disease";"PI3K events in ERBB2 signaling";"DAP12 signaling";"FRS-mediated FGFR1 signaling";"Interleukin-15 signaling";"MET activates RAS signaling";"PI-3K cascade:FGFR4";"FLT3 Signaling";"PI-3K cascade:FGFR2";"Signal regulatory protein family interactions"
XP_044251272.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_017003480.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017016141.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017016253.2	3	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_017009801.2	18	KEGG: 00330+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-6638;MetaCyc: PWY-6643;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-5913;KEGG: 00710+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00401+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1	"Arginine and proline metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Sulfolactate degradation III";"Coenzyme M biosynthesis II";"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Cysteine and methionine metabolism";"(R)-cysteate degradation";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation in photosynthetic organisms";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Novobiocin biosynthesis";"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine biosynthesis";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis"
XP_044248980.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_044250837.1	2	Reactome: R-HSA-168138;Reactome: R-HSA-983231	"Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production"
XP_016998759.2	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016998388.2	6	Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_016997917.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_017003335.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_017008096.1	26	Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-389977;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-190840;Reactome: R-HSA-8852276	"RHO GTPases Activate Formins";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Gap junction assembly";"Kinesins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_017000951.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017002256.2	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016995932.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_016997597.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_017014152.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_017004061.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016994808.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017000598.2	4	MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23	"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Sphingolipid metabolism"
XP_044251119.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_017008212.2	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_017006468.2	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_017000711.2	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_044248483.1	2	Reactome: R-HSA-8849473;Reactome: R-HSA-6791226	"PTK6 Expression";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044249421.1	42	Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-9616222;Reactome: R-HSA-8936459;Reactome: R-HSA-171306;Reactome: R-HSA-3214841;Reactome: R-HSA-8939236;Reactome: R-HSA-912446;Reactome: R-HSA-427389;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-5693607;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-5693571;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-69473;Reactome: R-HSA-3214858;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-977225;Reactome: R-HSA-2559586;Reactome: R-HSA-1221632;Reactome: R-HSA-110329;Reactome: R-HSA-9610379;Reactome: R-HSA-5625886;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-3214842;Reactome: R-HSA-1912408	"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"PRC2 methylates histones and DNA";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Packaging Of Telomere Ends";"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Meiotic recombination";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"Processing of DNA double-strand break ends";"DNA methylation";"Estrogen-dependent gene expression";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"Nonhomologous End-Joining (NHEJ)";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"G2/M DNA damage checkpoint";"RMTs methylate histone arginines";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Amyloid fiber formation";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic synapsis";"Cleavage of the damaged pyrimidine";"HCMV Late Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDMs demethylate histones";"Pre-NOTCH Transcription and Translation"
XP_016995452.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_017000066.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823	"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation"
XP_017003956.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_016994052.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017001712.2	5	KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556;KEGG: 00220+1.14.13.39;Reactome: R-HSA-392154;MetaCyc: PWY-4983	"Arginine and proline metabolism";"ROS and RNS production in phagocytes";"Arginine biosynthesis";"Nitric oxide stimulates guanylate cyclase";"Nitric oxide biosynthesis II (mammals)"
XP_017007729.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_017000585.2	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_017013953.2	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_017015640.2	11	Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5358565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5358606;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_016996621.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016993248.2	4	KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931;MetaCyc: PWY-6030;KEGG: 00790+1.14.16.4	"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis";"Folate biosynthesis"
XP_044248656.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_016992969.2	3	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_017005780.2	8	KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5;Reactome: R-HSA-6798695;Reactome: R-HSA-73614;MetaCyc: PWY-6556;MetaCyc: PWY-7199;MetaCyc: PWY-7181;MetaCyc: PWY-7193	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Neutrophil degranulation";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage I"
XP_017012754.2	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_017011790.2	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_017013145.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_017000458.2	5	Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Protein ubiquitination";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_017007515.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044248886.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_016994671.1	3	Reactome: R-HSA-9645722;Reactome: R-HSA-111471;Reactome: R-HSA-140837	"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation"
XP_017012067.2	5	MetaCyc: PWY-6124;MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6123	"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I"
XP_017009515.2	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_017012946.2	8	Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1	"Glycolysis";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Streptomycin biosynthesis";"Fructose and mannose metabolism"
XP_016999908.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5972;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-8041	"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis"
XP_017013726.2	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_017002025.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_017005202.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016994622.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_016993724.2	14	KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8053;Reactome: R-HSA-75109;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-7782;MetaCyc: PWY-8051;Reactome: R-HSA-1483213;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-1483191;KEGG: 00600+3.1.3.4	"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Triglyceride biosynthesis";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Synthesis of PE";"Stigma estolide biosynthesis";"Ether lipid metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of PC";"Sphingolipid metabolism"
XP_017004608.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044249034.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017014414.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_017012616.1	9	MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-6901;Reactome: R-HSA-70171;KEGG: 00710+1.2.1.12;MetaCyc: PWY-1042;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70263	"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis"
XP_044251699.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016996516.2	13	Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_017010865.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_017005025.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_016997177.2	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_044252157.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016993001.1	5	KEGG: 00230+2.7.4.10;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219	"Purine metabolism";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis"
XP_017015879.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017007627.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_017008555.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_017003728.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_017015971.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_017015616.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_017000437.2	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_016995991.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_044252194.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017000364.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_017007883.2	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_017015000.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_017003069.2	4	Reactome: R-HSA-4720475;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.258;KEGG: 00513+2.4.1.258	"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_017001384.2	5	MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate"
XP_017000581.2	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_017001716.2	7	Reactome: R-HSA-9023661;Reactome: R-HSA-9020265;Reactome: R-HSA-9018681;Reactome: R-HSA-9018896;Reactome: R-HSA-6798695;Reactome: R-HSA-2142691;Reactome: R-HSA-9018676	"Biosynthesis of E-series 18(R)-resolvins";"Biosynthesis of aspirin-triggered D-series resolvins";"Biosynthesis of protectins";"Biosynthesis of E-series 18(S)-resolvins";"Neutrophil degranulation";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of D-series resolvins"
XP_016996118.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017006655.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_016998532.2	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_017008689.2	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_044251670.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044252026.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_017012788.2	4	Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9	"Metabolism of folate and pterines";"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_016997859.2	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_017005146.2	11	Reactome: R-HSA-446205;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881;MetaCyc: PWY-7586;MetaCyc: PWY-882;KEGG: 00051+5.3.1.8;MetaCyc: PWY-5659;MetaCyc: PWY-7456;MetaCyc: PWY-3861;Reactome: R-HSA-4043916;MetaCyc: PWY-6992	"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Mannitol degradation II";"Defective MPI causes MPI-CDG (CDG-1b)";"1,5-anhydrofructose degradation"
XP_017008169.2	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
XP_017008427.2	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_017001401.2	15	MetaCyc: PWY-5484;KEGG: 00230+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-7218;MetaCyc: PWY-1042;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-5723	"Glycolysis II (from fructose 6-phosphate)";"Purine metabolism";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt"
XP_017005992.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_017005457.2	5	KEGG: 00750+2.7.1.35;Reactome: R-HSA-6798695;MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282	"Vitamin B6 metabolism";"Neutrophil degranulation";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_016994789.2	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_017010113.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044251193.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_044249007.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016995839.2	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_017001999.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_017011247.2	2	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"HATs acetylate histones";"Ub-specific processing proteases"
XP_016998832.2	3	Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-159230	"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA"
XP_017006523.2	9	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_017010241.2	19	KEGG: 00720+2.3.3.8;Reactome: R-HSA-163765;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00020+2.3.3.8;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;Reactome: R-HSA-75105;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;Reactome: R-HSA-6798695;MetaCyc: PWY-5172;MetaCyc: PWY-5538;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-7384	"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Propanoate metabolism";"Fatty acyl-CoA biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Neutrophil degranulation";"Acetyl-coa biosynthesis III (from citrate)";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_017006222.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017005047.2	13	Reactome: R-HSA-196757;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+6.3.4.3;MetaCyc: PWY-3841;MetaCyc: PWY-2201;MetaCyc: PWY-5030;MetaCyc: PWY-6613;MetaCyc: PWY-2161;KEGG: 00720+6.3.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-1722;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9	"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Folate transformations II (plants)";"Folate transformations I";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate polyglutamylation";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate"
XP_017008365.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044249260.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016999648.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_017009948.2	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_016994055.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016998691.2	14	MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5972	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)"
XP_017007506.2	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_044251268.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_016997519.2	9	Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome"
XP_017003164.2	7	KEGG: 00230+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6121;Reactome: R-HSA-73817	"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis"
XP_016993781.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-165159	"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"mTOR signalling"
XP_017007975.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_017003865.2	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_016998761.2	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_017011511.2	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
XP_017014340.1	24	Reactome: R-HSA-456926;Reactome: R-HSA-202040;Reactome: R-HSA-418597;Reactome: R-HSA-416482;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-418555;Reactome: R-HSA-392170;Reactome: R-HSA-163359;Reactome: R-HSA-418217;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-9009391;Reactome: R-HSA-420092;Reactome: R-HSA-418594;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-4086398;Reactome: R-HSA-6814122;Reactome: R-HSA-8964315;Reactome: R-HSA-400042;Reactome: R-HSA-432040	"Thrombin signalling through proteinase activated receptors (PARs)";"G-protein activation";"G alpha (z) signalling events";"G alpha (12/13) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (s) signalling events";"ADP signalling through P2Y purinoceptor 12";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"Extra-nuclear estrogen signaling";"Glucagon-type ligand receptors";"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"Ca2+ pathway";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through BTK";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_017003511.2	4	Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_017003585.2	5	Reactome: R-HSA-112382;Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_016997731.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_044250451.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_017011764.2	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_017013593.2	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_016999658.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016998664.1	42	MetaCyc: PWY-7007;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7778;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7726;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5109;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6863;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-7094;MetaCyc: PWY-7216;MetaCyc: PWY-5136;KEGG: 00627+4.2.1.17;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5177;MetaCyc: PWY-7654;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-1361;MetaCyc: PWY-7401;MetaCyc: PWY-6883;MetaCyc: PWY-6945;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-6583;MetaCyc: PWY-6944	"Methyl ketone biosynthesis (engineered)";"Toluene degradation";"2-methylpropene degradation";"Lysine degradation";"Caprolactam degradation";"Limonene and pinene degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid elongation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"Phenylalanine metabolism";"Fermentation to 2-methylbutanoate";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to hexanol (engineered)";"Tryptophan metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Geraniol degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Benzoate degradation";"beta-Alanine metabolism";"Carbon fixation pathways in prokaryotes";"Methyl tert-butyl ether degradation";"Butanoate metabolism";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid salvage";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Aminobenzoate degradation";"Fatty acid degradation";"Propanoate metabolism";"Glutaryl-coa degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Butanoate metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Benzoyl-coa degradation I (aerobic)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Pyruvate fermentation to butanol II (engineered)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Valine, leucine and isoleucine degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Pyruvate fermentation to butanol I";"Androstenedione degradation"
XP_016995620.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017009012.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_017000234.2	10	MetaCyc: PWY-1861;MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00680+2.7.1.11;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00030+2.7.1.11	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway"
XP_017001261.2	8	Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68949	"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin"
XP_017008049.2	14	MetaCyc: PWY-6969;MetaCyc: PWY-7279;MetaCyc: PWY-4302;Reactome: R-HSA-611105;KEGG: 00650+1.3.5.1;KEGG: 00190+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-561;Reactome: R-HSA-71403;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-5690	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"Respiratory electron transport";"Butanoate metabolism";"Oxidative phosphorylation";"Carbon fixation pathways in prokaryotes";"Aerobic respiration I (cytochrome c)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)"
XP_017012147.2	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_017003313.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_044249184.1	7	MetaCyc: PWY-6124;MetaCyc: PWY-7234;Reactome: R-HSA-73817;MetaCyc: PWY-7219;KEGG: 00230+4.3.2.2;KEGG: 00250+4.3.2.2;MetaCyc: PWY-6123	"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis I"
XP_017004662.2	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_017009915.2	56	Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-349425	"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Degradation of AXIN";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_017013283.2	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_017006929.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017008526.2	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism"
XP_016999843.2	5	MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation"
XP_017005703.2	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_016994123.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016994704.2	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_016994106.2	5	Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772	"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape"
XP_016994737.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017016156.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828	"TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis"
XP_044249871.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-6433	"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_017008000.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044250230.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_016997653.2	10	Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape"
XP_017005921.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017007877.2	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_017006494.2	9	KEGG: 00910+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-6964;MetaCyc: PWY-6963;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675	"Nitrogen metabolism";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle II";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III";"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)"
XP_017013842.2	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_044252042.1	22	Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-2500257;Reactome: R-HSA-6811558;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-141444;Reactome: R-HSA-5675221;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-432142;Reactome: R-HSA-9648025;Reactome: R-HSA-5358747	"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"Resolution of Sister Chromatid Cohesion";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Negative regulation of MAPK pathway";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Platelet sensitization by LDL";"EML4 and NUDC in mitotic spindle formation";"S33 mutants of beta-catenin aren't phosphorylated"
XP_044248460.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_017008651.2	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_017007590.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016996354.2	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_017011409.2	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_016997094.2	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_016999248.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044249469.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016993407.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_017005475.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_017001909.2	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_017006671.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_017013533.2	8	Reactome: R-HSA-71336;MetaCyc: PWY-1861;Reactome: R-HSA-6791462;Reactome: R-HSA-8950505;KEGG: 00030+2.2.1.2;Reactome: R-HSA-163754;MetaCyc: PWY-5723;Reactome: R-HSA-6791055	"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Pentose phosphate pathway";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Rubisco shunt";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P"
XP_017010585.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_017015133.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_017015955.1	10	Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243	"Signal transduction by L1";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_017009162.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017003020.2	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007	"Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy"
XP_016995775.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017008983.2	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_017001661.2	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_017008767.2	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_017012636.1	56	Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902	"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Degradation of AXIN";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity"
XP_044248611.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_017005763.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_017006616.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_044251120.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044250970.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_017014146.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016993332.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis"
XP_017006716.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_044252160.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_017002087.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_017011905.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_017005118.1	6	KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5693565;Reactome: R-HSA-8939211	"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ESR-mediated signaling"
XP_016998889.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_017001455.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_017015599.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017008859.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_017016048.2	2	Reactome: R-HSA-1268020;MetaCyc: PWY-7533	"Mitochondrial protein import";"Gliotoxin biosynthesis"
XP_016994774.2	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_044249771.1	3	Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161	"Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation"
XP_044249661.1	42	Reactome: R-HSA-606279;Reactome: R-HSA-110328;Reactome: R-HSA-5693565;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-69473;Reactome: R-HSA-3214858;Reactome: R-HSA-5693571;Reactome: R-HSA-3214842;Reactome: R-HSA-1912408;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-2559580;Reactome: R-HSA-1221632;Reactome: R-HSA-977225;Reactome: R-HSA-2559586;Reactome: R-HSA-5625886;Reactome: R-HSA-9610379;Reactome: R-HSA-110329;Reactome: R-HSA-5617472;Reactome: R-HSA-171306;Reactome: R-HSA-8936459;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-212300;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-427389;Reactome: R-HSA-912446;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-5693607;Reactome: R-HSA-3214841;Reactome: R-HSA-8939236	"Deposition of new CENPA-containing nucleosomes at the centromere";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"G2/M DNA damage checkpoint";"RMTs methylate histone arginines";"Nonhomologous End-Joining (NHEJ)";"HDMs demethylate histones";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Oxidative Stress Induced Senescence";"Meiotic synapsis";"Amyloid fiber formation";"DNA Damage/Telomere Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HCMV Late Events";"Cleavage of the damaged pyrimidine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Packaging Of Telomere Ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"PRC2 methylates histones and DNA";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"HCMV Early Events";"Transcriptional regulation by small RNAs";"DNA methylation";"Estrogen-dependent gene expression";"HATs acetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic recombination";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"Processing of DNA double-strand break ends";"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_016998682.2	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_016998776.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016996474.2	4	Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_017005867.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016994904.2	9	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6782315;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"tRNA modification in the nucleus and cytosol";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_017004860.2	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_044250205.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_016998556.2	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_017005251.2	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_017011773.2	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017013345.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017005836.2	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_016997417.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-390450	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC"
XP_017004238.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016998890.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_044251091.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017013315.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_017014712.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_017013520.2	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_017002077.2	56	Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780	"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Separation of Sister Chromatids";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome"
XP_017001868.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_017008056.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_017007665.2	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_017013400.2	5	Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_016999962.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017013351.2	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_017015898.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_016994254.2	16	Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-983168	"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017004607.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_017002812.2	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_016992627.2	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_017005714.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_017006834.2	4	MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32	"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism"
XP_044249843.1	56	Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590	"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Degradation of AXIN";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling"
XP_016996114.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016997770.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_044248905.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_017005526.2	3	Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins"
XP_044251194.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_017010773.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_016994527.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016994632.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition"
XP_017006617.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_017010277.2	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_017009766.2	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_044248484.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-8849473	"Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression"
XP_016999281.2	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_016996665.2	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_017007585.1	14	MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis"
XP_044251174.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044250972.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017008166.2	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
XP_016993463.2	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_044252016.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_017015784.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_044249914.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016999212.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017006772.2	8	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6791226	"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017009330.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017002554.1	42	Reactome: R-HSA-3214841;Reactome: R-HSA-8939236;Reactome: R-HSA-427389;Reactome: R-HSA-912446;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-5693607;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-8936459;Reactome: R-HSA-171306;Reactome: R-HSA-977225;Reactome: R-HSA-2559586;Reactome: R-HSA-1221632;Reactome: R-HSA-110329;Reactome: R-HSA-9610379;Reactome: R-HSA-5625886;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-3214842;Reactome: R-HSA-1912408;Reactome: R-HSA-5693571;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-69473;Reactome: R-HSA-3214858;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-5693565	"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic recombination";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"Processing of DNA double-strand break ends";"DNA methylation";"Estrogen-dependent gene expression";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"HCMV Early Events";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Packaging Of Telomere Ends";"Amyloid fiber formation";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic synapsis";"Cleavage of the damaged pyrimidine";"HCMV Late Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDMs demethylate histones";"Pre-NOTCH Transcription and Translation";"Nonhomologous End-Joining (NHEJ)";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"G2/M DNA damage checkpoint";"RMTs methylate histone arginines";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_016995116.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016994377.2	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_017015161.2	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_044251157.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis"
XP_044251801.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_044250478.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044252022.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_017011746.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_017009163.2	8	Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"mTOR signalling";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_017012918.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017012656.2	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_016995667.1	3	Reactome: R-HSA-71336;KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44	"Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway"
XP_017002548.2	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_044250332.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_017012784.2	20	Reactome: R-HSA-110320;Reactome: R-HSA-69473;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-6804756	"Translesion Synthesis by POLH";"G2/M DNA damage checkpoint";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Regulation of TP53 Activity through Phosphorylation"
XP_044251202.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016994411.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_016995241.2	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_017015362.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_017007885.2	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_044249751.1	3	KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403;MetaCyc: PWY-4041	"Glutathione metabolism";"Glutathione synthesis and recycling";"Gamma-glutamyl cycle"
XP_017005831.2	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_016998068.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_017007248.2	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_017005178.1	7	Reactome: R-HSA-5689880;Reactome: R-HSA-201722;Reactome: R-HSA-606279;Reactome: R-HSA-5689603;Reactome: R-HSA-171319;Reactome: R-HSA-3214847;Reactome: R-HSA-5696394	"Ub-specific processing proteases";"Formation of the beta-catenin:TCF transactivating complex";"Deposition of new CENPA-containing nucleosomes at the centromere";"UCH proteinases";"Telomere Extension By Telomerase";"HATs acetylate histones";"DNA Damage Recognition in GG-NER"
XP_017008325.1	57	Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174184	"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Degradation of AXIN";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_017006329.2	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_017006133.2	2	Reactome: R-HSA-196741;Reactome: R-HSA-3359473	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD"
XP_017000650.2	10	Reactome: R-HSA-201688;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756	"WNT mediated activation of DVL";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"Signal transduction by L1";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation"
XP_017011745.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_016998820.2	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_016995479.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_017012638.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_017007444.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_017008928.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044250654.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_044249422.1	42	Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-606279;Reactome: R-HSA-110328;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-3214858;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-1912408;Reactome: R-HSA-3214842;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-977225;Reactome: R-HSA-1221632;Reactome: R-HSA-110329;Reactome: R-HSA-5625886;Reactome: R-HSA-9610379;Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-171306;Reactome: R-HSA-8936459;Reactome: R-HSA-9609690;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-212300;Reactome: R-HSA-3214847;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-5578749;Reactome: R-HSA-8939236;Reactome: R-HSA-3214841;Reactome: R-HSA-5693607;Reactome: R-HSA-427389;Reactome: R-HSA-912446;Reactome: R-HSA-73772;Reactome: R-HSA-73728	"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"RMTs methylate histone arginines";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Pre-NOTCH Transcription and Translation";"HDMs demethylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"Amyloid fiber formation";"Meiotic synapsis";"Cleavage of the damaged pyrimidine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HCMV Late Events";"Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"Packaging Of Telomere Ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Early Events";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"HATs acetylate histones";"DNA methylation";"Estrogen-dependent gene expression";"Transcriptional regulation by small RNAs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PKMTs methylate histone lysines";"Processing of DNA double-strand break ends";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic recombination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening"
XP_017011910.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_017004543.1	4	Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912	"Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis"
XP_016992594.1	3	Reactome: R-HSA-3299685;Reactome: R-HSA-5628897;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes";"Glutathione metabolism"
XP_016999304.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_017009546.2	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_017014441.2	14	MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-6433	"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_016997299.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_017013888.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane"
XP_017004639.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_017015564.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_016992727.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_017004137.2	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_044251622.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016994782.2	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_016994802.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016997056.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016999672.1	26	Reactome: R-HSA-1362277;Reactome: R-HSA-6782210;Reactome: R-HSA-69183;Reactome: R-HSA-5656169;Reactome: R-HSA-4615885;Reactome: R-HSA-8866654;Reactome: R-HSA-174437;Reactome: R-HSA-6804114;Reactome: R-HSA-174414;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-6782135;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-174417;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-69205	"Transcription of E2F targets under negative control by DREAM complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the lagging strand";"Termination of translesion DNA synthesis";"SUMOylation of DNA replication proteins";"E3 ubiquitin ligases ubiquitinate target proteins";"Removal of the Flap Intermediate from the C-strand";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Processive synthesis on the C-strand of the telomere";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"G1/S-Specific Transcription"
XP_017014447.2	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_017008287.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_017002618.1	7	Reactome: R-HSA-2173796;Reactome: R-HSA-381340;Reactome: R-HSA-2122947;Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional regulation of white adipocyte differentiation";"NOTCH1 Intracellular Domain Regulates Transcription";"Generic Transcription Pathway";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_016994409.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_017016175.2	4	KEGG: 00532+2.4.2.26;KEGG: 00534+2.4.2.26;Reactome: R-HSA-1971475;MetaCyc: PWY-6557	"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan-protein linkage region biosynthesis"
XP_016999151.1	7	KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-70268	"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism"
XP_017014448.2	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_016999165.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_017005002.2	56	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-180585	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G"
XP_017015147.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_017006452.1	11	Reactome: R-HSA-71403;MetaCyc: PWY-7268;MetaCyc: PWY-7124;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6549;KEGG: 00720+1.1.1.42;MetaCyc: PWY-5913	"Citric acid cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Ethylene biosynthesis V (engineered)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glutathione metabolism";"L-glutamine biosynthesis III";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)"
XP_016992866.2	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_017010570.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044248463.1	2	Reactome: R-HSA-9614657;Reactome: R-HSA-5205685	"FOXO-mediated transcription of cell death genes";"Pink/Parkin Mediated Mitophagy"
XP_016997204.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_017001790.2	7	Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-6798695;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389957	"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Neutrophil degranulation";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_017014803.2	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_016998870.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016993793.2	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_017000574.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_017014507.2	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_017006398.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_017011968.2	7	Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-8953750	"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6"
XP_017004197.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288	"mTOR signalling";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1"
XP_017001945.2	6	Reactome: R-HSA-110362;Reactome: R-HSA-162594;Reactome: R-HSA-5651801;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-5685939	"POLB-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"HDR through MMEJ (alt-NHEJ)"
XP_017004928.2	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_017000335.1	3	Reactome: R-HSA-75105;MetaCyc: PWY-5987;MetaCyc: PWY-5996	"Fatty acyl-CoA biosynthesis";"Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)"
XP_044249642.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016999466.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016993911.1	25	Reactome: R-HSA-8941858;Reactome: R-HSA-8941333;Reactome: R-HSA-8940973;Reactome: R-HSA-8935964;Reactome: R-HSA-8934593;Reactome: R-HSA-8931987;Reactome: R-HSA-8939247;Reactome: R-HSA-8939242;Reactome: R-HSA-8939245;Reactome: R-HSA-8951911;Reactome: R-HSA-8936459;Reactome: R-HSA-9616222;Reactome: R-HSA-8939256;Reactome: R-HSA-8939902;Reactome: R-HSA-8939246;Reactome: R-HSA-8939236;Reactome: R-HSA-8941332;Reactome: R-HSA-8939243;Reactome: R-HSA-8878166;Reactome: R-HSA-8951936;Reactome: R-HSA-8941326;Reactome: R-HSA-8877330;Reactome: R-HSA-8949275;Reactome: R-HSA-8941284;Reactome: R-HSA-9018519	"Regulation of RUNX3 expression and activity";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates expression of components of tight junctions";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in WNT signaling";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates genes involved in cell migration";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional regulation by RUNX2";"RUNX3 regulates p14-ARF";"RUNX2 regulates bone development";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX2 regulates chondrocyte maturation";"Estrogen-dependent gene expression"
XP_017010803.2	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_016992536.2	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_044251199.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_017008618.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_017012432.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_017012787.1	8	KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"Oxidative phosphorylation";"Ion channel transport";"ATP biosynthesis";"Photosynthesis";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_044249347.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_016998906.2	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_016993958.2	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_017000571.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_017003819.2	8	Reactome: R-HSA-8943724;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841	"Regulation of PTEN gene transcription";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines"
XP_017000009.2	9	Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332	"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1"
XP_016998278.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016995067.2	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_017009004.2	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_017007517.2	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_017009164.2	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_017013407.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044251282.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_017007022.2	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_044252197.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044249234.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_017006402.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_017011028.1	13	MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7198;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7222;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Pyrimidine metabolism";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_016993935.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017015475.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_016994372.1	15	Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-9603505	"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"NTRK3 as a dependence receptor"
XP_017010874.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044248709.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017006096.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_017012301.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017015782.2	2	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
XP_017008357.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902	"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation"
XP_044251318.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_017007182.2	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_016998344.1	9	MetaCyc: PWY-5743;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-7117	"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_044251698.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_017011850.2	3	Reactome: R-HSA-1660661;Reactome: R-HSA-9609523;Reactome: R-HSA-6798695	"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation"
XP_017002299.1	9	MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11	"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"G alpha (q) signalling events";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism"
XP_016999634.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_017012676.2	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8869496	"Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_016997435.2	5	Reactome: R-HSA-75896;Reactome: R-HSA-9033241;Reactome: R-HSA-9033500;KEGG: 00565+2.5.1.26;MetaCyc: PWY-7782	"Plasmalogen biosynthesis";"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins";"Ether lipid metabolism";"Plasmalogen biosynthesis"
XP_016996937.2	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_016995131.2	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_017013433.2	9	Reactome: R-HSA-191859;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-2151201	"snRNP Assembly";"RORA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis"
XP_017000117.2	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_016996251.2	17	Reactome: R-HSA-4086398;Reactome: R-HSA-450321;Reactome: R-HSA-450302;Reactome: R-HSA-5689880;Reactome: R-HSA-5357956;Reactome: R-HSA-9014325;Reactome: R-HSA-975163;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-937072;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-202424;Reactome: R-HSA-937042;Reactome: R-HSA-2871837;Reactome: R-HSA-168638;Reactome: R-HSA-1169091	"Ca2+ pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"activated TAK1 mediates p38 MAPK activation";"Ub-specific processing proteases";"TNFR1-induced NFkappaB signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"Downstream TCR signaling";"IRAK2 mediated activation of TAK1 complex";"FCERI mediated NF-kB activation";"NOD1/2 Signaling Pathway";"Activation of NF-kappaB in B cells"
XP_017014821.1	6	KEGG: 00040+5.1.3.1;KEGG: 00710+5.1.3.1;MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00030+5.1.3.1;Reactome: R-HSA-71336	"Pentose and glucuronate interconversions";"Carbon fixation in photosynthetic organisms";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_017005070.2	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_016992585.2	22	Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-9648025;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-2500257;Reactome: R-HSA-5673000;Reactome: R-HSA-2467813;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-6811558	"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"EML4 and NUDC in mitotic spindle formation";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"Resolution of Sister Chromatid Cohesion";"RAF activation";"Separation of Sister Chromatids";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_016999230.2	9	Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_017002522.2	3	Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-6804760	"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation"
XP_016993165.2	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_017002220.2	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_016996947.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-9609690	"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events"
XP_017008167.2	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
XP_017006429.1	5	MetaCyc: PWY-7176;KEGG: 00240+6.3.4.2;Reactome: R-HSA-499943;MetaCyc: PWY-7185;MetaCyc: PWY-7177	"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I";"UTP and CTP dephosphorylation II"
XP_017014551.2	5	Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_017005504.1	12	MetaCyc: PWY-3801;KEGG: 00561+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7817;MetaCyc: PWY-6527;KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9	"Sucrose degradation II (sucrose synthase)";"Glycerolipid metabolism";"Glycogen synthesis";"Pentose and glucuronate interconversions";"Sucrose biosynthesis II";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_044249247.1	11	Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-3000170;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-202733;Reactome: R-HSA-975634	"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Syndecan interactions";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport"
XP_016996485.2	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_016996060.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_017007946.2	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_044249663.1	5	Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_044249514.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-164378	"PKA activation";"Glucagon signaling in metabolic regulation";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation in glucagon signalling"
XP_044251599.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_017012715.2	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016997987.2	5	Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-73863	"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination"
XP_017001726.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017012915.2	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_016998546.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-429958	"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_016992823.2	9	Reactome: R-HSA-9657050;Reactome: R-HSA-9656255;Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-5649702;Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-9656256	"Defective OGG1 Localization";"Defective OGG1 Substrate Binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Defective OGG1 Substrate Processing"
XP_016993035.2	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_017016110.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_017002893.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-6798695;Reactome: R-HSA-1660499;Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Neutrophil degranulation";"Synthesis of PIPs at the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_017011336.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_044250035.1	4	KEGG: 00564+3.1.1.7;Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Glycerophospholipid metabolism";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_044251763.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_017002710.2	13	KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2022857	"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosaminoglycan degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation"
XP_017005020.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_017000708.1	6	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_016997763.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044251172.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017012513.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_017002364.2	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_017007967.2	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_017012648.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017009865.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017014449.2	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_016992877.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044251920.1	10	Reactome: R-HSA-8936459;Reactome: R-HSA-9022702;Reactome: R-HSA-9022699;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-9022538	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands";"MECP2 regulates neuronal receptors and channels";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"Loss of MECP2 binding ability to 5mC-DNA"
XP_016997919.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_017012053.2	16	Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693548;Reactome: R-HSA-201722	"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"Estrogen-dependent gene expression";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Sensing of DNA Double Strand Breaks";"Formation of the beta-catenin:TCF transactivating complex"
XP_016996281.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952	"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Long-term potentiation";"HSF1-dependent transactivation";"RAF activation";"Signaling by BRAF and RAF fusions"
XP_044250157.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_017000216.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044248823.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017001128.2	14	KEGG: 00720+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-6969;MetaCyc: PWY-7279;MetaCyc: PWY-4302;KEGG: 00650+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-561;Reactome: R-HSA-71403;KEGG: 00020+1.3.5.1	"Carbon fixation pathways in prokaryotes";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"Butanoate metabolism";"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)"
XP_017014353.2	1	Reactome: R-HSA-3295583	"TRP channels"
XP_017013025.2	20	MetaCyc: PWY-7007;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-7340;MetaCyc: PWY-735;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7337;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7606;MetaCyc: PWY-7574;MetaCyc: PWY-7854;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338	"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoyl-coa degradation II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)"
XP_044252178.1	6	MetaCyc: PWY-7761;MetaCyc: PWY-5381;Reactome: R-HSA-196807;KEGG: 00760+6.3.1.5;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653	"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_017001832.2	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_017008881.2	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_017005083.2	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_017000305.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
XP_017002857.2	5	MetaCyc: PWY-6168;MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-7863	"Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"Roseoflavin biosynthesis"
XP_016995226.2	9	KEGG: 00350+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00950+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00400+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00360+2.6.1.5	"Tyrosine metabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tyrosine catabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Novobiocin biosynthesis";"Cysteine and methionine metabolism";"Phenylalanine metabolism"
XP_044252177.1	6	MetaCyc: PWY-7761;MetaCyc: PWY-5381;Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5	"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism"
XP_017007887.2	7	Reactome: R-HSA-70221;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;MetaCyc: PWY-5941;Reactome: R-HSA-6798695;MetaCyc: PWY-6737;MetaCyc: PWY-6724	"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Glycogen degradation II";"Neutrophil degranulation";"Starch degradation V";"Starch degradation II"
XP_017004205.1	5	KEGG: 00230+6.3.5.3;Reactome: R-HSA-73817;MetaCyc: PWY-6122;MetaCyc: PWY-6277;MetaCyc: PWY-6121	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_017002061.2	7	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_017002228.2	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_017006966.2	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044250555.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090	"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures"
XP_044251429.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_017000491.2	4	Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-3899300;Reactome: R-HSA-9646399	"Chaperone Mediated Autophagy";"Late endosomal microautophagy";"SUMOylation of transcription cofactors";"Aggrephagy"
XP_017013485.2	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214	"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_017006281.2	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_016993990.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017000593.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_017010092.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044250649.1	5	KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I"
XP_017008331.2	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_017015914.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016999201.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_017011196.2	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_017006197.2	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_016993341.2	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_016994038.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016994793.2	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_017001886.2	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_017007870.1	11	Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-2022928	"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"HS-GAG biosynthesis"
XP_016998407.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_017002255.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016996697.2	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2"
XP_016998331.2	9	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-198323	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol"
XP_017014343.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017011246.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016993368.1	7	KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517	"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid"
XP_017002523.2	3	Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-6804760	"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation"
XP_016995092.1	7	Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-180746;Reactome: R-HSA-203927	"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein";"MicroRNA (miRNA) biogenesis"
XP_017009407.2	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_017012853.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044251454.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_017009320.1	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_017004579.2	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_044252017.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_016997605.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017003608.2	10	Reactome: R-HSA-380972;Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-200425;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483	"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Carnitine metabolism";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs"
XP_017008170.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_017001915.2	6	Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-8874211	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"CREB3 factors activate genes"
XP_017015179.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-192823	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Translation initiation complex formation";"Viral mRNA Translation"
XP_016994992.2	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_017010242.2	19	Reactome: R-HSA-71403;KEGG: 00720+2.3.3.8;Reactome: R-HSA-163765;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00020+2.3.3.8;Reactome: R-HSA-75105;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5913;Reactome: R-HSA-6798695;MetaCyc: PWY-5172;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-6969	"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Propanoate metabolism";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Neutrophil degranulation";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_017014150.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017004511.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_044252078.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism"
XP_017015927.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016992756.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_017000872.2	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_044248751.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017012357.2	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_016998598.2	12	KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5628897	"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Activation of AMPK downstream of NMDARs";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection";"Macroautophagy";"PI3K-Akt signaling pathway";"TP53 Regulates Metabolic Genes"
XP_017009994.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones"
XP_017001173.2	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_016993088.2	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_017010278.2	5	Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558	"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)"
XP_016994113.2	5	KEGG: 00650+4.1.3.4;KEGG: 00072+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00281+4.1.3.4;MetaCyc: PWY-5074	"Butanoate metabolism";"Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Mevalonate degradation"
XP_017004717.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_017010654.2	7	MetaCyc: PWY-6121;MetaCyc: PWY-7282;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6277;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817	"5-aminoimidazole ribonucleotide biosynthesis I";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_017015181.2	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_017003997.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_016997821.2	3	Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)"
XP_017011742.2	22	Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7592;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7727;MetaCyc: PWY-7726;MetaCyc: PWY-7728;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7606;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7049;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053;MetaCyc: PWY-7602;MetaCyc: PWY-5353;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6958	"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)"
XP_017008053.1	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
XP_044251922.1	10	Reactome: R-HSA-9022538;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-3899300;Reactome: R-HSA-9615017;Reactome: R-HSA-9022692;Reactome: R-HSA-983231;Reactome: R-HSA-9022699;Reactome: R-HSA-8936459;Reactome: R-HSA-9022702	"Loss of MECP2 binding ability to 5mC-DNA";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of MECP2 expression and activity";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates neuronal receptors and channels";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands"
XP_044249189.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_017005154.2	2	KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"Glycine degradation"
XP_017010774.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016993372.2	5	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-71403;Reactome: R-HSA-611105	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_017009996.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_017007217.2	13	MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5537;MetaCyc: PWY-5538	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI"
XP_017007008.2	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_017006287.2	7	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_017006827.2	10	Reactome: R-HSA-70171;KEGG: 00010+2.7.2.3;MetaCyc: PWY-1042;KEGG: 00710+2.7.2.3;Reactome: R-HSA-70263;MetaCyc: PWY-7003;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-6901	"Glycolysis";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation"
XP_017004663.2	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_017008143.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_017001289.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016998277.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_017004832.2	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_017011333.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017005279.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_017013674.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_017014124.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_017008262.1	9	Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-6794361;Reactome: R-HSA-438066;Reactome: R-HSA-3928662;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736	"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Neurexins and neuroligins";"Unblocking of NMDA receptors, glutamate binding and activation";"EPHB-mediated forward signaling";"Synaptic adhesion-like molecules";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors"
XP_016994990.2	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_017004918.2	3	Reactome: R-HSA-71262;KEGG: 00310+1.14.11.8;MetaCyc: PWY-6100	"Carnitine synthesis";"Lysine degradation";"L-carnitine biosynthesis"
XP_016997889.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs"
XP_016998915.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_017005395.2	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_017003487.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016992469.2	3	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_017013314.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-191859	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly"
XP_017004085.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_017008278.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_017002916.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_017015779.2	30	Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-5696395;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-2564830;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-167152	"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"RNA Polymerase I Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_017003011.2	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_017009878.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_016994282.2	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_016997704.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_044251280.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_044249829.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017016018.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_017012031.2	4	Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400	"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER"
XP_017005342.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_017005515.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_017007484.2	7	Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-749476	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation"
XP_017008282.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016993216.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_017008332.2	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_016998893.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_044248590.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017006154.2	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_044252192.1	10	Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756	"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"Signal transduction by L1";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation"
XP_017002628.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016998387.2	8	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_016995026.2	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_017014774.2	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_016995437.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016999508.1	6	Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-418597;Reactome: R-HSA-114516;Reactome: R-HSA-76005	"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+"
XP_016994138.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016996178.2	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_016999646.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_017004002.2	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_017010843.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016997792.2	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_017011110.2	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_017002671.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_017014574.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_017012743.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_017012984.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017009880.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_017009125.1	6	Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253	"Triglyceride catabolism";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Circadian Clock"
XP_017003944.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_017007632.2	9	MetaCyc: PWY-7902;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-6118;KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385	"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)"
XP_017002558.1	4	Reactome: R-HSA-352230;Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-5660862	"Amino acid transport across the plasma membrane";"Basigin interactions";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)"
XP_017012923.2	4	Reactome: R-HSA-379726;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716	"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_017015689.2	9	KEGG: 00790+3.5.4.16;MetaCyc: PWY-6703;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-7852;MetaCyc: PWY-6147;MetaCyc: PWY-5664;MetaCyc: PWY-5663	"Folate biosynthesis";"Preq0 biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I"
XP_044248817.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016992523.2	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_017012214.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_017008464.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-428930	"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor"
XP_016992873.2	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_017004182.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_017003319.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_017013296.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016998520.2	4	Reactome: R-HSA-8939211;Reactome: R-HSA-3371497;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568	"ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Estrogen-dependent gene expression";"Attenuation phase"
XP_017005126.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs"
XP_016998674.2	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_016995240.2	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_044250609.1	4	Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14	"Pyrimidine catabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism"
XP_044252073.1	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_017002323.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_017005787.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_017012123.2	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_016997598.2	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_016998083.2	12	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-381038;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"XBP1(S) activates chaperone genes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic"
XP_017016239.2	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_017009666.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017003185.2	4	Reactome: R-HSA-9615710;Reactome: R-HSA-3899300;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399	"Late endosomal microautophagy";"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy";"Aggrephagy"
XP_017000810.2	7	Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-1362277	"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex"
XP_017002324.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_017003190.2	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_017001734.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_017001691.2	33	Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-141444;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-2500257;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-4085377;Reactome: R-HSA-180910	"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Resolution of Sister Chromatid Cohesion";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs"
XP_016998253.2	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_017008345.2	7	Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.67;KEGG: 04070+2.7.1.67;MetaCyc: PWY-6351;Reactome: R-HSA-1660499	"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the plasma membrane"
XP_016999904.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_017012483.2	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_017008612.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_017007582.2	14	MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs"
XP_017008755.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_017009154.2	4	MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;Reactome: R-HSA-70688	"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism"
XP_017000495.2	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_017006630.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_017011906.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_017015311.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_017006315.2	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism"
XP_017003186.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_016993122.2	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_017013343.2	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_044250507.1	6	MetaCyc: PWY-7395;MetaCyc: PWY-7077;KEGG: 00520+3.5.1.25;Reactome: R-HSA-446210;KEGG: 00052+3.5.1.25;MetaCyc: PWY-6906	"D-galactosamine and N-acetyl-D-galactosamine degradation";"N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Galactose metabolism";"Chitin derivatives degradation"
XP_016996940.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690	"Aggrephagy";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"HCMV Early Events"
XP_016997143.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_017008225.2	12	MetaCyc: PWY-5872;MetaCyc: PWY-5873;MetaCyc: PWY-6708;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5857;MetaCyc: PWY-6978;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;Reactome: R-HSA-1268020;MetaCyc: PWY-5870;MetaCyc: PWY-5856;MetaCyc: PWY-5871	"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)"
XP_017005942.2	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_017014921.2	6	MetaCyc: PWY-6118;MetaCyc: PWY-6952;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;Reactome: R-HSA-163560	"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Glycerol degradation I";"Glycerophospholipid metabolism";"Synthesis of PA";"Triglyceride catabolism"
XP_017015657.2	3	MetaCyc: PWY-7999;Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4	"Vitamin K-epoxide cycle";"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_017010785.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016993959.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_017007756.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016996286.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-9022692	"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Long-term potentiation";"RAF activation";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity"
XP_017010103.2	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_017003123.2	7	Reactome: R-HSA-373080;Reactome: R-HSA-5362798;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-5635838;Reactome: R-HSA-5658034	"Class B/2 (Secretin family receptors)";"Release of Hh-Np from the secreting cell";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np"
XP_017011795.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_017011704.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017011144.2	10	Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-9620244;Reactome: R-HSA-447038	"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation";"NrCAM interactions"
XP_016999520.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044251578.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016993287.2	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_044251168.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016993963.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_017015619.2	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_017013443.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels"
XP_017003596.2	9	KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-112043;Reactome: R-HSA-416476	"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events";"G alpha (q) signalling events"
XP_017013346.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017001293.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_044250102.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_017007553.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_017010082.2	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_016993395.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044249040.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_017010779.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044251314.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Repression of WNT target genes";"RUNX3 regulates WNT signaling"
XP_017013217.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane"
XP_017003414.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_017003098.2	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_017010571.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016997714.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044250981.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044252131.1	9	Reactome: R-HSA-1855204;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;MetaCyc: PWY-8052;Reactome: R-HSA-416476;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11	"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"PLC beta mediated events";"Inositol phosphate metabolism"
XP_017013455.2	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_044250333.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_017015888.2	5	Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-376172;Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24	"VEGFA-VEGFR2 Pathway";"p38MAPK events";"DSCAM interactions";"NOD1/2 Signaling Pathway";"mTOR signaling pathway"
XP_016994192.2	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_044249621.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_044248922.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_017000775.2	7	MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7	"Betanidin degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis"
XP_017006312.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_044251098.1	7	Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-1442490	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Collagen degradation"
XP_017012937.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016999322.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_017009336.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016999961.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_017009566.2	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_017005604.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016999509.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-76005;Reactome: R-HSA-418597;Reactome: R-HSA-114516	"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Disinhibition of SNARE formation"
XP_016998801.2	30	Reactome: R-HSA-400253;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-917937;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-69231;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-2565942;Reactome: R-HSA-195253;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-1169091;Reactome: R-HSA-1170546;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-5684264;Reactome: R-HSA-2644607;Reactome: R-HSA-2122947;Reactome: R-HSA-187577	"Circadian Clock";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Iron uptake and transport";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cyclin D associated events in G1";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of beta-catenin by the destruction complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of NF-kappaB in B cells";"Prolactin receptor signaling";"Downstream TCR signaling";"Neddylation";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"SCF(Skp2)-mediated degradation of p27/p21"
XP_044250681.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_017005589.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017009210.2	12	KEGG: 00720+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00620+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-5132;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00630+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-6672	"Carbon fixation pathways in prokaryotes";"Adlupulone and adhumulone biosynthesis";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"L-isoleucine biosynthesis V";"Lupulone and humulone biosynthesis";"Methane metabolism";"Colupulone and cohumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Propanoate metabolism";"Chitin degradation to ethanol";"Cis-genanyl-coa degradation"
XP_016999279.2	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_017015005.2	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_017008351.2	11	KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8052;KEGG: 00565+3.1.3.4;Reactome: R-HSA-2029485;MetaCyc: PWY-7782;MetaCyc: PWY-8051	"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Plasmalogen biosynthesis";"Anandamide biosynthesis I"
XP_017015872.2	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_044250456.1	4	KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation"
XP_016999136.2	7	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_017008312.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_017012654.2	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-1834941;Reactome: R-HSA-3249367;Reactome: R-HSA-3134975	"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines";"Regulation of innate immune responses to cytosolic DNA"
XP_017015319.2	4	MetaCyc: PWY-7805;Reactome: R-HSA-71737;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807	"(aminomethyl)phosphonate degradation";"Pyrophosphate hydrolysis";"Oxidative phosphorylation";"Glyphosate degradation III"
XP_044251249.1	12	Reactome: R-HSA-9010553;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-450408;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-72662	"Regulation of expression of SLITs and ROBOs";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ISG15 antiviral mechanism";"Translation initiation complex formation";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"
XP_017010828.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016992383.2	9	Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167161	"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation"
XP_016999140.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_017015412.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_017014446.2	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_017002306.2	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_017001383.2	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_017006528.1	27	Reactome: R-HSA-5610785;Reactome: R-HSA-5467337;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-196299;Reactome: R-HSA-198323;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-3371453;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-195253;KEGG: 05170+2.7.11.1;Reactome: R-HSA-75815;Reactome: R-HSA-399956;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5358751;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5250924;Reactome: R-HSA-5674400;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752	"GLI3 is processed to GLI3R by the proteasome";"APC truncation mutants have impaired AXIN binding";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Beta-catenin phosphorylation cascade";"AKT phosphorylates targets in the cytosol";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Regulation of HSF1-mediated heat shock response";"Thermogenesis";"Relaxin signaling pathway";"Degradation of beta-catenin by the destruction complex";"Human immunodeficiency virus 1 infection";"Ubiquitin-dependent degradation of Cyclin D";"CRMPs in Sema3A signaling";"PI3K-Akt signaling pathway";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Human papillomavirus infection";"S45 mutants of beta-catenin aren't phosphorylated";"Human cytomegalovirus infection";"mTOR signaling pathway";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by AKT1 E17K in Cancer";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated"
XP_044249254.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_017014928.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_017001024.2	5	Reactome: R-HSA-3772470;Reactome: R-HSA-4641262;Reactome: R-HSA-4641263;Reactome: R-HSA-5340588;Reactome: R-HSA-201681	"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Regulation of FZD by ubiquitination";"RNF mutants show enhanced WNT signaling and proliferation";"TCF dependent signaling in response to WNT"
XP_017011083.1	20	MetaCyc: PWY-7337;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7340;MetaCyc: PWY-7291;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-7007;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-7606;MetaCyc: PWY-7858;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6	"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism"
XP_017008916.2	4	MetaCyc: PWY-7174;Reactome: R-HSA-72731;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_044249288.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016993834.2	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_017006153.2	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_044250809.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_017014968.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044250607.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016999906.2	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_016997379.1	6	Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-77588	"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_017015925.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044249151.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016996087.2	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_017004052.2	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_044248748.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016999611.2	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_016993637.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_017007673.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017007913.2	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_044250103.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_016996288.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-111932	"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"RAF activation";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB"
XP_017000565.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_017015947.1	28	Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-6782210;Reactome: R-HSA-3371511;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-176187;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-69473;Reactome: R-HSA-110312;Reactome: R-HSA-6804756;Reactome: R-HSA-3371453;Reactome: R-HSA-5656121;Reactome: R-HSA-5358565;Reactome: R-HSA-69166;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-6783310;Reactome: R-HSA-5693607	"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HSF1 activation";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Activation of ATR in response to replication stress";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"G2/M DNA damage checkpoint";"Translesion synthesis by REV1";"Regulation of TP53 Activity through Phosphorylation";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends"
XP_016993916.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044248646.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_017016139.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016992774.2	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_016997489.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017002944.2	6	Reactome: R-HSA-5632968;Reactome: R-HSA-5632927;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-6796648;Reactome: R-HSA-5358606	"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_044248835.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_016999918.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044251879.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016998874.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_017001345.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing"
XP_017004245.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017015563.2	11	Reactome: R-HSA-6782135;Reactome: R-HSA-174430;Reactome: R-HSA-6782210;Reactome: R-HSA-68962;Reactome: R-HSA-5656169;Reactome: R-HSA-68952;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-110314	"Dual incision in TC-NER";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of the pre-replicative complex";"Termination of translesion DNA synthesis";"DNA replication initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex"
XP_017012914.2	2	KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608	"Aminoacyl-tRNA biosynthesis";"Platelet degranulation"
XP_017003049.2	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_017014303.1	9	Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_016995631.2	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_017010157.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_044251848.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_017011732.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_016998821.2	5	Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_017001877.2	11	Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-212436;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-383280;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519	"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Generic Transcription Pathway";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Nuclear Receptor transcription pathway";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"RORA activates gene expression";"Estrogen-dependent gene expression"
XP_016993036.2	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_017000279.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_017006821.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016994057.2	6	Reactome: R-HSA-446210;MetaCyc: PWY-5514;MetaCyc: PWY-6749;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.3;KEGG: 00520+5.4.2.10	"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II";"CMP-legionaminate biosynthesis I";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_044249540.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_017004452.2	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_044252024.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_017000473.1	56	Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling"
XP_017002911.2	6	Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181430	"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle"
XP_017012728.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017011714.2	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_017007760.2	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_017004682.1	6	Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Neutrophil degranulation";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_044250952.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017011550.2	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_044251607.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_016999280.2	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_017012023.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016999676.2	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
XP_016998509.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_017008264.2	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_016999089.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044252208.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_017013826.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_044249484.1	42	Reactome: R-HSA-3214842;Reactome: R-HSA-1912408;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-2559580;Reactome: R-HSA-977225;Reactome: R-HSA-2559586;Reactome: R-HSA-1221632;Reactome: R-HSA-9610379;Reactome: R-HSA-110329;Reactome: R-HSA-5625886;Reactome: R-HSA-5617472;Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-69473;Reactome: R-HSA-3214858;Reactome: R-HSA-5693571;Reactome: R-HSA-5578749;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-912446;Reactome: R-HSA-427389;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-5693607;Reactome: R-HSA-3214841;Reactome: R-HSA-8939236;Reactome: R-HSA-171306;Reactome: R-HSA-8936459;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-9616222;Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-9609690	"HDMs demethylate histones";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Oxidative Stress Induced Senescence";"Amyloid fiber formation";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic synapsis";"HCMV Late Events";"Cleavage of the damaged pyrimidine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"G2/M DNA damage checkpoint";"RMTs methylate histone arginines";"Nonhomologous End-Joining (NHEJ)";"Transcriptional regulation by small RNAs";"DNA methylation";"Estrogen-dependent gene expression";"HATs acetylate histones";"Meiotic recombination";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"Processing of DNA double-strand break ends";"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Packaging Of Telomere Ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"Transcriptional regulation of granulopoiesis";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events"
XP_016997479.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016998217.2	7	Reactome: R-HSA-70635;MetaCyc: PWY-6922;MetaCyc: PWY-46;MetaCyc: PWY-31;KEGG: 00220+3.5.3.1;MetaCyc: PWY-4984;KEGG: 00330+3.5.3.1	"Urea cycle";"L-Ndelta-acetylornithine biosynthesis";"Putrescine biosynthesis III";"Canavanine degradation";"Arginine biosynthesis";"Urea cycle";"Arginine and proline metabolism"
XP_017011140.2	12	Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-447038;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-451308;Reactome: R-HSA-9609736	"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Synaptic adhesion-like molecules";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors"
XP_017008878.2	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_017013436.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740	"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs"
XP_017007502.2	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_044248612.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_017008665.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016995357.2	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_016999615.2	8	KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;Reactome: R-HSA-5083629;MetaCyc: PWY-7979	"Other types of O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)"
XP_017004231.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016998879.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_017002611.2	3	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)"
XP_017006435.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_044251753.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044250195.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_016996954.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399	"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Aggrephagy"
XP_017004505.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016995499.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_017007481.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_017007715.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016992532.2	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_017000269.2	10	MetaCyc: PWY-6613;MetaCyc: PWY-5030;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-1722;MetaCyc: PWY-5497;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841	"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Folate transformations I";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)"
XP_017015488.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_016999709.1	10	Reactome: R-HSA-72731;Reactome: R-HSA-381042;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-382556;Reactome: R-HSA-72649;Reactome: R-HSA-9648895	"Recycling of eIF2:GDP";"PERK regulates gene expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"ABC-family proteins mediated transport";"Translation initiation complex formation";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_017002439.2	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_017005065.2	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_017001229.1	8	Reactome: R-HSA-6798695;MetaCyc: PWY-7179;MetaCyc: PWY-6611;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;Reactome: R-HSA-5683826;KEGG: 00230+3.5.4.4	"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Surfactant metabolism";"Purine metabolism"
XP_016999189.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017012329.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_016995450.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044248695.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_017014478.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016998913.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_017015983.2	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_017007500.2	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_017015137.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_017010053.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_017015138.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_017006674.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_017015962.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_017007166.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044251293.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_017006877.2	15	MetaCyc: PWY-5723;Reactome: R-HSA-70171;MetaCyc: PWY-7383;MetaCyc: PWY-2221;MetaCyc: PWY-1042;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-6142;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;KEGG: 00230+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-5484	"Rubisco shunt";"Glycolysis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Purine metabolism";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)"
XP_017015487.2	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_017012940.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016994702.2	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_017010425.2	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_017014697.2	5	Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-983170	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_016996074.2	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016999285.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_017000334.1	3	Reactome: R-HSA-75105;MetaCyc: PWY-5996;MetaCyc: PWY-5987	"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Sorgoleone biosynthesis"
XP_017001470.2	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_017002551.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044248718.1	1	Reactome: R-HSA-428643	"Organic anion transporters"
XP_017003912.2	6	MetaCyc: PWY-4381;MetaCyc: PWY-5744;MetaCyc: PWY-6722;MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-5789	"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_017004132.2	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_017014392.2	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_017008079.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044252006.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044251230.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_017007684.2	8	KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Starch and sucrose metabolism"
XP_017004978.2	14	MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7036	"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II"
XP_017006526.2	9	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_016997055.2	5	KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;Reactome: R-HSA-189451;MetaCyc: PWY-5189;Reactome: R-HSA-6798695	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation"
XP_017007471.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_017013998.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017000576.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_016992539.2	13	MetaCyc: PWY-6370;Reactome: R-HSA-196836;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;KEGG: 00053+1.8.5.1;MetaCyc: PWY-2261;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18+1.8.5.1	"Ascorbate recycling (cytosolic)";"Vitamin C (ascorbate) metabolism";"Glutathione conjugation";"Drug metabolism - other enzymes";"Ascorbate and aldarate metabolism";"Ascorbate glutathione cycle";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione metabolism"
XP_016999971.2	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_017002789.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_017013581.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_017012655.2	8	Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68616	"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication"
XP_017013230.2	9	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_017003080.2	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_017015930.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_017013042.2	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_044250454.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_017010749.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016997225.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004	"Clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_044249780.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017006129.2	2	Reactome: R-HSA-500753;Reactome: R-HSA-73621	"Pyrimidine biosynthesis";"Pyrimidine catabolism"
XP_017004076.2	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_044252149.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016998417.2	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017008250.2	5	Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_017003977.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_017006399.2	12	KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-601;MetaCyc: PWY-801;KEGG: 00270+4.4.1.13;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6309;MetaCyc: PWY-6936;MetaCyc: PWY-2821;MetaCyc: PWY-1187;Reactome: R-HSA-71240;MetaCyc: PWY-7901	"Selenocompound metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tryptophan";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from homomethionine";"Tryptophan catabolism";"Glucosinolate biosynthesis from tyrosine"
XP_044252237.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_016999659.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_017013146.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016996214.2	20	Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-176187;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-69473;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-6804756;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397	"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"G2/M DNA damage checkpoint";"Polymerase switching";"Translesion Synthesis by POLH";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_017015861.2	3	Reactome: R-HSA-5689877;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394	"Josephin domain DUBs";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER"
XP_016997378.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_017009148.2	5	Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912420;Reactome: R-HSA-1912408;Reactome: R-HSA-1912399	"Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_016996347.2	2	Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_016999282.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_017003954.2	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_017007059.1	5	MetaCyc: PWY-5514;MetaCyc: PWY-6855;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_016994080.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017011361.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_017015952.1	7	Reactome: R-HSA-3371453;Reactome: R-HSA-381042;Reactome: R-HSA-381183;Reactome: R-HSA-381033;Reactome: R-HSA-114608;Reactome: R-HSA-381070;Reactome: R-HSA-983170	"Regulation of HSF1-mediated heat shock response";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation";"IRE1alpha activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_016994479.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044248633.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_017008461.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-456926	"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_044250090.1	27	Reactome: R-HSA-77595;Reactome: R-HSA-674695;Reactome: R-HSA-191859;Reactome: R-HSA-975957;Reactome: R-HSA-159230;Reactome: R-HSA-167242;Reactome: R-HSA-9010553;Reactome: R-HSA-111367;Reactome: R-HSA-8851708;Reactome: R-HSA-77588;Reactome: R-HSA-167152;Reactome: R-HSA-159236;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-159227;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-112382;Reactome: R-HSA-6803529;Reactome: R-HSA-72187;Reactome: R-HSA-167200;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-975956	"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Pre-transcription Events";"snRNP Assembly";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of the SLBP Dependant Mature mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Regulation of expression of SLITs and ROBOs";"SLBP independent Processing of Histone Pre-mRNAs";"Signaling by FGFR2 IIIa TM";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Formation of HIV elongation complex in the absence of HIV Tat";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Transport of the SLBP independent Mature mRNA";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"Formation of RNA Pol II elongation complex";"FGFR2 alternative splicing";"mRNA 3'-end processing";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_044249781.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016997485.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044248816.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_017005908.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017012792.2	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_017014417.2	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_017001577.2	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_016994103.2	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_017009113.2	4	Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;MetaCyc: PWY-6517	"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"N-acetylglucosamine degradation II"
XP_017007915.1	24	Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295	"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Gap junction assembly";"Kinesins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"MHC class II antigen presentation"
XP_017005171.2	19	MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7221;MetaCyc: PWY-7184;MetaCyc: PWY-7227;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-7176;MetaCyc: PWY-7197;Reactome: R-HSA-380320;KEGG: 00230+2.7.4.6;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;Reactome: R-HSA-380270;MetaCyc: PWY-7226	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Recruitment of NuMA to mitotic centrosomes";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Recruitment of mitotic centrosome proteins and complexes";"Guanosine deoxyribonucleotides de novo biosynthesis I"
XP_017004352.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016999689.2	4	Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044251316.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling"
XP_016993461.2	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_017007009.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044251387.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_016996272.2	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_016996778.2	7	KEGG: 04070+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-8856828;Reactome: R-HSA-1855204;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1660499	"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Clathrin-mediated endocytosis";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane"
XP_016999617.2	3	Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807	"Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_016999666.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs"
XP_017012894.2	5	Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_044251793.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_016992905.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017014949.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016999169.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017003684.2	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_044249835.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_017000233.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740	"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs"
XP_017015200.2	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_044250849.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016999107.2	3	MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)"
XP_016995072.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6807505	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes"
XP_044248818.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_017010054.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_017014503.2	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_044249692.1	14	Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-203927	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis"
XP_044249163.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_017007939.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017003744.2	5	KEGG: 00020+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3	"Citrate cycle (TCA cycle)";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes"
XP_017011915.2	3	Reactome: R-HSA-3065676;Reactome: R-HSA-3065678;Reactome: R-HSA-983168	"SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016995970.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-194840	"RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle"
XP_017005100.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-69052	"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state"
XP_017005869.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_017013428.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_016998763.2	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_017010772.2	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_017011357.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902	"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation"
XP_017009504.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017015857.2	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_016996956.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044248710.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017005749.2	3	KEGG: 00240+3.6.1.17;Reactome: R-HSA-3299685;KEGG: 00230+3.6.1.17	"Pyrimidine metabolism";"Detoxification of Reactive Oxygen Species";"Purine metabolism"
XP_017004407.2	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6807505	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"RNA polymerase II transcribes snRNA genes"
XP_017007641.2	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_017006954.2	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016994784.2	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_044249490.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_017005011.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_016997590.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane"
XP_017008742.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_017010203.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017010313.2	18	MetaCyc: PWY-5913;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00950+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00960+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7383	"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"(R)-cysteate degradation";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Phenylalanine metabolism";"Coenzyme M biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine biosynthesis";"Tyrosine metabolism";"Novobiocin biosynthesis";"Alanine, aspartate and glutamate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine and proline metabolism";"Sulfolactate degradation III";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_044248615.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_017013294.1	6	MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7290;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122	"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis"
XP_017012709.2	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_017012909.2	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-4061	"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I"
XP_017005266.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016998531.2	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_017000007.2	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_016994408.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016993345.2	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_017009117.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_017008564.2	2	Reactome: R-HSA-2393930;MetaCyc: PWY-8061	"Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification II"
XP_017001745.1	3	KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_017010192.2	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_016995982.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_017007250.2	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016993030.2	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_016999696.2	8	Reactome: R-HSA-6781823;Reactome: R-HSA-5689880;Reactome: R-HSA-8948747;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases";"Regulation of PTEN localization";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
XP_017008785.2	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_017004222.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016999564.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_017004998.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_017011628.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017013162.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_017004510.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_044249107.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_017005033.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_044252112.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_017003424.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly"
XP_017004766.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_017010476.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_016999633.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016998887.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016996215.2	9	Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779	"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_016997780.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_017011160.2	10	Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932	"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Long-term potentiation";"Synaptic adhesion-like molecules"
XP_017010757.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-8963684;Reactome: R-HSA-156590	"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism";"Glutathione conjugation"
XP_044251572.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_044249222.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_017008532.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_017010431.2	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_044248693.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_044249952.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_044251702.1	3	Reactome: R-HSA-5657562;Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3	"Essential fructosuria";"Fructose catabolism";"Fructose and mannose metabolism"
XP_017004509.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_016997362.2	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_017000402.1	8	KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"Oxidative phosphorylation";"Ion channel transport";"Photosynthesis";"ATP biosynthesis";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_017008809.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017004385.2	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_017015953.1	7	Reactome: R-HSA-381183;Reactome: R-HSA-114608;Reactome: R-HSA-381033;Reactome: R-HSA-381042;Reactome: R-HSA-3371453;Reactome: R-HSA-381070;Reactome: R-HSA-983170	"ATF6 (ATF6-alpha) activates chaperone genes";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperones";"PERK regulates gene expression";"Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_017015916.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044251143.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_017010777.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016997258.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017009598.2	20	Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-69473;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-6804756;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-174411	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Polymerase switching";"G2/M DNA damage checkpoint";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Polymerase switching on the C-strand of the telomere"
XP_017014500.2	3	Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23	"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism"
XP_044249925.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017012995.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"Translation initiation complex formation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
XP_017009031.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_017013297.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017008274.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_017004728.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_017014850.1	4	KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558;MetaCyc: PWY-5331;KEGG: 00270+1.13.11.20	"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine";"Taurine biosynthesis I";"Cysteine and methionine metabolism"
XP_044250148.1	4	Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-352230	"Basigin interactions";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane"
XP_017003959.2	6	Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560	"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Triglyceride catabolism"
XP_016999277.2	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_016993179.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016994780.2	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_016992527.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_044251534.1	6	KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;MetaCyc: PWY-6364;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56	"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system"
XP_017011299.2	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016997574.2	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_016994297.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_017003347.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_017002518.2	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_016996290.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571	"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"RAF activation";"HSF1-dependent transactivation"
XP_017012025.2	4	Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis"
XP_016997615.2	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_017009829.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044251569.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_017007738.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_017015320.2	17	Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167158;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167200	"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_017013502.2	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016993979.2	4	MetaCyc: PWY-7268;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"Glutathione metabolism"
XP_016995388.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017010994.2	27	Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453	"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"snRNP Assembly";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response"
XP_044249494.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_016997205.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_016995209.2	11	Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-164378	"Glucagon signaling in metabolic regulation";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (i) signalling events";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation in glucagon signalling"
XP_016999497.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_016992786.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_016996065.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_016994903.2	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_017005510.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_017011697.2	17	MetaCyc: PWY-6644;MetaCyc: PWY-6609;KEGG: 00760+2.4.2.1;Reactome: R-HSA-74217;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6620;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;MetaCyc: PWY-6627;MetaCyc: PWY-4202;MetaCyc: PWY-5695;MetaCyc: PWY-6611;MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.1;Reactome: R-HSA-6798695	"Fluoroacetate and fluorothreonine biosynthesis";"Adenine and adenosine salvage III";"Nicotinate and nicotinamide metabolism";"Purine salvage";"Purine metabolism";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Salinosporamide A biosynthesis";"Arsenate detoxification I (mammalian)";"Inosine 5'-phosphate degradation";"Adenine and adenosine salvage V";"Guanosine nucleotides degradation III";"Purine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Neutrophil degranulation"
XP_017002442.2	5	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_017012635.2	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_017012530.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_017010599.2	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_017008247.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016994326.2	3	KEGG: 00310+2.1.1.60;Reactome: R-HSA-2514859;Reactome: R-HSA-8876725	"Lysine degradation";"Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation"
XP_017003611.2	10	Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-200425;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-2151209	"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Carnitine metabolism";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
XP_017005310.2	4	Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_017006968.2	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_017010577.2	4	Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Laminin interactions";"MET activates PTK2 signaling"
XP_044252019.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_016996230.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016993775.2	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_017010096.2	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016993991.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017004596.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_017000118.2	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_044250453.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_016995242.2	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_017007655.2	16	Reactome: R-HSA-167590;Reactome: R-HSA-3928665;Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-196025;Reactome: R-HSA-8866427;Reactome: R-HSA-190873;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-5140745;Reactome: R-HSA-8856828;Reactome: R-HSA-2132295;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-164939;Reactome: R-HSA-437239	"Nef Mediated CD4 Down-regulation";"EPH-ephrin mediated repulsion of cells";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"Formation of annular gap junctions";"VLDLR internalisation and degradation";"Gap junction degradation";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis";"MHC class II antigen presentation";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"Nef mediated downregulation of CD28 cell surface expression";"Recycling pathway of L1"
XP_017014114.1	8	Reactome: R-HSA-182218;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9636467;Reactome: R-HSA-167590;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Blockage of phagosome acidification";"Nef Mediated CD4 Down-regulation";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_017013557.2	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_017009516.2	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_044249336.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_017002380.2	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_044250218.1	9	KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902	"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)"
XP_017012118.2	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_044251000.1	3	Reactome: R-HSA-1474151;Reactome: R-HSA-203615;KEGG: 00790+1.1.1.153	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation";"Folate biosynthesis"
XP_017007462.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_017009085.2	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_017008523.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044251491.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_017011700.2	17	MetaCyc: PWY-6620;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-6609;MetaCyc: PWY-6644;KEGG: 00760+2.4.2.1;Reactome: R-HSA-74217;MetaCyc: PWY-6611;MetaCyc: PWY-6608;MetaCyc: PWY-5532;Reactome: R-HSA-74259;KEGG: 00240+2.4.2.1;Reactome: R-HSA-6798695;MetaCyc: PWY-6627;MetaCyc: PWY-7179-1;MetaCyc: PWY-5695;MetaCyc: PWY-4202	"Guanine and guanosine salvage";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Fluoroacetate and fluorothreonine biosynthesis";"Nicotinate and nicotinamide metabolism";"Purine salvage";"Adenine and adenosine salvage V";"Guanosine nucleotides degradation III";"Nucleoside and nucleotide degradation (archaea)";"Purine catabolism";"Pyrimidine metabolism";"Neutrophil degranulation";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation II";"Inosine 5'-phosphate degradation";"Arsenate detoxification I (mammalian)"
XP_017004116.2	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_017014720.1	9	MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-5744	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation"
XP_044251033.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_016994000.2	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_016996007.2	10	Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6807505	"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes"
XP_017001143.2	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_017006377.2	56	Reactome: R-HSA-5668541;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346	"TNFR2 non-canonical NF-kB pathway";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis"
XP_017005030.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_016998799.2	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_017013865.2	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_016992947.2	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_017014589.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_017011202.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_017002914.2	6	Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_017000254.2	1	Reactome: R-HSA-74217	"Purine salvage"
XP_017006870.2	6	MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7290;Reactome: R-HSA-5083632	"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_017011893.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016996608.2	1	Reactome: R-HSA-6803529	"FGFR2 alternative splicing"
XP_044248574.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_017011617.2	29	MetaCyc: PWY-6871;KEGG: 00010+1.1.1.1;KEGG: 00625+1.1.1.1;KEGG: 00982+1.1.1.1;MetaCyc: PWY-5751;MetaCyc: PWY-5082;KEGG: 00980+1.1.1.1;KEGG: 00830+1.1.1.1;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-7111;MetaCyc: PWY-6313;MetaCyc: PWY-5078;MetaCyc: PWY-7118;MetaCyc: PWY-3162;KEGG: 00071+1.1.1.1;MetaCyc: PWY-6802;MetaCyc: PWY-7396;MetaCyc: PWY-5076;MetaCyc: PWY-5480;MetaCyc: PWY-5079;MetaCyc: PWY-6342;MetaCyc: PWY-7013;MetaCyc: PWY-6587;MetaCyc: PWY-6333;KEGG: 00260+1.1.1.1;MetaCyc: PWY-5057;KEGG: 00592+1.1.1.1;KEGG: 00350+1.1.1.1	"3-methylbutanol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Chloroalkane and chloroalkene degradation";"Drug metabolism - cytochrome P450";"Phenylethanol biosynthesis";"L-methionine degradation III";"Metabolism of xenobiotics by cytochrome P450";"Retinol metabolism";"Naphthalene degradation";"Pyruvate fermentation to ethanol II";"Pyruvate fermentation to isobutanol (engineered)";"Serotonin degradation";"L-isoleucine degradation II";"Chitin degradation to ethanol";"L-tryptophan degradation V (side chain pathway)";"Fatty acid degradation";"Salidroside biosynthesis";"Butanol and isobutanol biosynthesis (engineered)";"L-leucine degradation III";"Pyruvate fermentation to ethanol I";"L-phenylalanine degradation III";"Noradrenaline and adrenaline degradation";"(S)-propane-1,2-diol degradation";"Pyruvate fermentation to ethanol III";"Acetaldehyde biosynthesis I";"Glycine, serine and threonine metabolism";"L-valine degradation II";"alpha-Linolenic acid metabolism";"Tyrosine metabolism"
XP_016998245.2	9	Reactome: R-HSA-4420097;Reactome: R-HSA-2871809;Reactome: R-HSA-5218920;Reactome: R-HSA-114604;Reactome: R-HSA-416482;Reactome: R-HSA-2871796;Reactome: R-HSA-193648;Reactome: R-HSA-2029482;Reactome: R-HSA-194840	"VEGFA-VEGFR2 Pathway";"FCERI mediated Ca+2 mobilization";"VEGFR2 mediated vascular permeability";"GPVI-mediated activation cascade";"G alpha (12/13) signalling events";"FCERI mediated MAPK activation";"NRAGE signals death through JNK";"Regulation of actin dynamics for phagocytic cup formation";"Rho GTPase cycle"
XP_017015333.2	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016998775.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_017005072.2	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_017005120.2	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_017011158.2	12	Reactome: R-HSA-451308;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001	"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"NrCAM interactions";"Synaptic adhesion-like molecules";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade"
XP_016994334.1	7	Reactome: R-HSA-70263;KEGG: 00030+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00710+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00680+3.1.3.11;KEGG: 00051+3.1.3.11	"Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Fructose and mannose metabolism"
XP_017001638.2	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_016996147.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017005212.2	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_017004778.2	57	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-8854050	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_044248714.1	3	MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531	"Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus"
XP_017013897.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044250655.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_017009870.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_044249491.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_017010877.2	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_016993441.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
XP_017010122.2	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_017006805.2	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_017001047.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_017009228.2	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_017011146.2	8	Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;MetaCyc: PWY-7221	"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis"
XP_044248836.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_017009799.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017008838.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"Viral mRNA Translation";"Translation initiation complex formation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
XP_017002440.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016992553.2	2	Reactome: R-HSA-6793080;Reactome: R-HSA-2151201	"rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis"
XP_017004609.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_017011003.2	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_016999146.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016995342.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016996958.2	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_016995933.1	12	Reactome: R-HSA-76061;Reactome: R-HSA-427413;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73772;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-5250924;Reactome: R-HSA-76071;Reactome: R-HSA-73863;Reactome: R-HSA-73762	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation"
XP_017000821.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016993789.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016999283.2	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_016995732.2	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_017002309.2	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_017003743.2	33	Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-170822;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-2500257;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-5663220;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-68877	"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Resolution of Sister Chromatid Cohesion";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"RHO GTPases Activate Formins";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Mitotic Prometaphase"
XP_016996760.2	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_017005631.1	56	Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-174178	"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Degradation of AXIN";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_016998966.2	14	MetaCyc: PWY-6453;Reactome: R-HSA-9018519;MetaCyc: PWY-7587;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;Reactome: R-HSA-75109;MetaCyc: PWY-8053;Reactome: R-HSA-2426168;MetaCyc: PWY-7411;Reactome: R-HSA-8931987;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055	"Stigma estolide biosynthesis";"Estrogen-dependent gene expression";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Anandamide biosynthesis II";"Activation of gene expression by SREBF (SREBP)";"Phosphatidate biosynthesis (yeast)";"RUNX1 regulates estrogen receptor mediated transcription";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis"
XP_017001353.2	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_017002862.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016999644.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017014668.2	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_044251005.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_044251484.1	4	Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320	"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Anchoring fibril formation"
XP_044251281.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_016992644.2	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_017011411.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044251114.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_017011149.2	8	Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8	"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism"
XP_017002764.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016996884.2	2	Reactome: R-HSA-202733;Reactome: R-HSA-140875	"Cell surface interactions at the vascular wall";"Common Pathway of Fibrin Clot Formation"
XP_016997155.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016994697.2	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_017008061.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016995216.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_017015020.2	14	Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-426486	"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis"
XP_017002072.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017006952.2	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016997047.2	12	MetaCyc: PWY-6932;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00920+2.7.1.25;KEGG: 00920+2.7.7.4;Reactome: R-HSA-174362;MetaCyc: PWY-5278;KEGG: 00450+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00230+2.7.1.25;KEGG: 00261+2.7.7.4	"Selenate reduction";"Sulfate activation for sulfonation";"Purine metabolism";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Sulfur metabolism";"Transport and synthesis of PAPS";"Sulfite oxidation III";"Selenocompound metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Monobactam biosynthesis"
XP_017012480.2	6	Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_017009338.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_017009054.2	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_017004410.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017008871.2	6	KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143	"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis"
XP_016996046.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_017000484.2	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_017013391.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044249420.1	42	Reactome: R-HSA-3214842;Reactome: R-HSA-1912408;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-2559580;Reactome: R-HSA-2559586;Reactome: R-HSA-977225;Reactome: R-HSA-1221632;Reactome: R-HSA-110329;Reactome: R-HSA-5625886;Reactome: R-HSA-9610379;Reactome: R-HSA-5617472;Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-69473;Reactome: R-HSA-3214858;Reactome: R-HSA-5693571;Reactome: R-HSA-5578749;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-912446;Reactome: R-HSA-427389;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-5693607;Reactome: R-HSA-3214841;Reactome: R-HSA-8939236;Reactome: R-HSA-171306;Reactome: R-HSA-8936459;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-212300;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-9609690	"HDMs demethylate histones";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Oxidative Stress Induced Senescence";"DNA Damage/Telomere Stress Induced Senescence";"Amyloid fiber formation";"Meiotic synapsis";"Cleavage of the damaged pyrimidine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HCMV Late Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"G2/M DNA damage checkpoint";"RMTs methylate histone arginines";"Nonhomologous End-Joining (NHEJ)";"Transcriptional regulation by small RNAs";"DNA methylation";"Estrogen-dependent gene expression";"HATs acetylate histones";"Meiotic recombination";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Processing of DNA double-strand break ends";"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Packaging Of Telomere Ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"PRC2 methylates histones and DNA";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"HCMV Early Events"
XP_044249831.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017010472.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_017015230.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017001776.2	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_044251758.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_017013564.2	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044251824.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017003103.2	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_017006403.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_017013569.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_017015984.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_017000656.2	56	Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257	"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Separation of Sister Chromatids";"Degradation of AXIN"
XP_044248921.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016994104.2	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_044251726.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_017000482.2	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_016993762.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044250182.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_016997164.2	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_017000220.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044249406.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016992775.2	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_044251262.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_044249451.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017005642.2	4	KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004	"Pentose phosphate pathway";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I"
XP_016996749.2	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_017006712.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_016998266.2	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_017001663.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017004302.2	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016992611.2	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_017003494.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017007041.2	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_016999900.2	7	KEGG: 00400+1.14.16.1;Reactome: R-HSA-8964208;KEGG: 00360+1.14.16.1;KEGG: 00790+1.14.16.1;MetaCyc: PWY-7158;Reactome: R-HSA-2160456;MetaCyc: PWY-6134	"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Phenylalanine metabolism";"Folate biosynthesis";"L-phenylalanine degradation V";"Phenylketonuria";"L-tyrosine biosynthesis IV"
XP_016997964.2	8	Reactome: R-HSA-5683826;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-6611;MetaCyc: PWY-7179;Reactome: R-HSA-6798695	"Surfactant metabolism";"Purine metabolism";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation"
XP_017007212.1	4	MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167160	"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_044251606.1	4	MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32	"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism"
XP_017007185.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_017014106.1	10	Reactome: R-HSA-111457;Reactome: R-HSA-111458;Reactome: R-HSA-611105;Reactome: R-HSA-111463;Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-2151201;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-9627069	"Release of apoptotic factors from the mitochondria";"Formation of apoptosome";"Respiratory electron transport";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity"
XP_017011179.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_017010999.2	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_044251584.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_017005165.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_017012375.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_016995354.2	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_044251716.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_017014846.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017004196.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016996056.1	5	Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-8856825	"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis"
XP_016999083.2	2	Reactome: R-HSA-6783310;Reactome: R-HSA-110314	"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex"
XP_016997191.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044250852.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_016999629.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_017003733.2	15	Reactome: R-HSA-416476;Reactome: R-HSA-388841;Reactome: R-HSA-1266695;Reactome: R-HSA-9009391;Reactome: R-HSA-912526;Reactome: R-HSA-1257604;Reactome: R-HSA-912631;Reactome: R-HSA-114604;Reactome: R-HSA-1660499;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-2219530;Reactome: R-HSA-1433557;Reactome: R-HSA-389357;Reactome: R-HSA-6811558	"G alpha (q) signalling events";"Costimulation by the CD28 family";"Interleukin-7 signaling";"Extra-nuclear estrogen signaling";"Interleukin receptor SHC signaling";"PIP3 activates AKT signaling";"Regulation of signaling by CBL";"GPVI-mediated activation cascade";"Synthesis of PIPs at the plasma membrane";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by SCF-KIT";"CD28 dependent PI3K/Akt signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_017007491.2	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_044249220.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_044248929.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_044250070.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_017004730.2	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_044249434.1	13	Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;MetaCyc: PWY-6807;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2206308;Reactome: R-HSA-4341670;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.23	"Neutrophil degranulation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Sialic acid metabolism";"Glycosphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"HS-GAG degradation";"Glycosaminoglycan degradation";"MPS IV - Morquio syndrome B";"Defective NEU1 causes sialidosis";"Galactose metabolism";"Keratan sulfate degradation";"Other glycan degradation"
XP_017004135.2	18	KEGG: 00720+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00270+1.1.1.37;Reactome: R-HSA-70263;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00680+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-7115;MetaCyc: PWY-561	"Carbon fixation pathways in prokaryotes";"Formaldehyde assimilation I (serine pathway)";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Cysteine and methionine metabolism";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_016995954.2	4	MetaCyc: PWY-5350;KEGG: 00920+2.8.1.1;MetaCyc: PWY-7927;Reactome: R-HSA-1614558	"Thiosulfate disproportionation IV (rhodanese)";"Sulfur metabolism";"Sulfide oxidation IV (mitochondria)";"Degradation of cysteine and homocysteine"
XP_016994365.2	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_016998243.2	9	Reactome: R-HSA-2029482;Reactome: R-HSA-193648;Reactome: R-HSA-2871796;Reactome: R-HSA-194840;Reactome: R-HSA-114604;Reactome: R-HSA-5218920;Reactome: R-HSA-4420097;Reactome: R-HSA-2871809;Reactome: R-HSA-416482	"Regulation of actin dynamics for phagocytic cup formation";"NRAGE signals death through JNK";"FCERI mediated MAPK activation";"Rho GTPase cycle";"GPVI-mediated activation cascade";"VEGFR2 mediated vascular permeability";"VEGFA-VEGFR2 Pathway";"FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events"
XP_017014860.2	5	Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_017002656.2	5	Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_016997174.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_017007179.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_017003349.2	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_017003820.2	8	Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-8943724	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"Regulation of PTEN gene transcription"
XP_017011426.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_017011784.2	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_044251201.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_044250307.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73779	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_016994812.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017015980.2	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_017005544.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016997095.2	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_016997747.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044248654.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_017013868.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016995205.2	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_016995158.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_017001755.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_017006219.2	8	Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-69183	"DNA replication initiation";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand"
XP_016998762.2	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_044251649.1	22	Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-195253;Reactome: R-HSA-5675221;Reactome: R-HSA-141444;Reactome: R-HSA-5358747;Reactome: R-HSA-9648025;Reactome: R-HSA-432142;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-2467813;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-2500257;Reactome: R-HSA-389513;Reactome: R-HSA-6811558;Reactome: R-HSA-5467337;Reactome: R-HSA-196299	"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Degradation of beta-catenin by the destruction complex";"Negative regulation of MAPK pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S33 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Platelet sensitization by LDL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"Separation of Sister Chromatids";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade"
XP_017010015.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs"
XP_044252027.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_017011209.2	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8854691;KEGG: 04660+2.7.10.2	"Interleukin-4 and Interleukin-13 signaling";"Interleukin-20 family signaling";"T cell receptor signaling pathway"
XP_017004551.1	4	MetaCyc: PWY-5912;MetaCyc: PWY-5041;Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6	"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II";"Methylation";"Cysteine and methionine metabolism"
XP_044249161.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_017006193.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_044251529.1	14	Reactome: R-HSA-9033241;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.15;Reactome: R-HSA-75896;MetaCyc: PWY-7411;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.42;Reactome: R-HSA-1483166;MetaCyc: PWY-5667	"Peroxisomal protein import";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I"
XP_017003269.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_017003723.2	3	MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2	"UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism"
XP_017015198.2	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_017015486.2	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_017010302.2	1	Reactome: R-HSA-5676934	"Protein repair"
XP_016996071.2	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016999335.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017012815.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016996567.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_017007544.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017012470.2	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_017000045.2	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_017015193.2	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"Kinesins"
XP_016998750.2	6	Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226	"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017013836.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016999331.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017005410.2	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_044250914.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_017000649.2	10	Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695	"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation"
XP_017009873.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_017006392.2	6	Reactome: R-HSA-8936459;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8951664;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Neddylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines"
XP_017012371.2	10	Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756	"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation"
XP_017009810.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016994777.2	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_044249455.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_017011659.2	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_017008623.2	7	Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-6783310;Reactome: R-HSA-5693607	"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends"
XP_017011911.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044249786.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044251957.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_016997003.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_044250409.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016996952.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-9609690	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events"
XP_044249179.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_017014609.2	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_016997401.2	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_044251117.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_017010793.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016997839.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016999215.2	4	Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin"
XP_017002048.2	7	Reactome: R-HSA-1483191;MetaCyc: PWY-7818;MetaCyc: PWY-7886;Reactome: R-HSA-1483213;MetaCyc: PWY-3385;MetaCyc: PWY-7782;KEGG: 00564+2.7.1.32+2.7.1.82	"Synthesis of PC";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PE";"Choline biosynthesis I";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism"
XP_017007507.2	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_017015613.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_017003523.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_017007661.2	14	MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7619;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7724	"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_017008720.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016996448.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_016996794.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017010022.2	3	MetaCyc: PWY-6558;Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_016998905.2	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016994994.1	56	Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-202424	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Downstream TCR signaling"
XP_017000563.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_016995352.2	19	Reactome: R-HSA-8957275;Reactome: R-HSA-8856825;Reactome: R-HSA-3000480;Reactome: R-HSA-381426;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423;Reactome: R-HSA-8964038;Reactome: R-HSA-8963901;Reactome: R-HSA-3000471;Reactome: R-HSA-8964046;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-3000497;Reactome: R-HSA-3000484;Reactome: R-HSA-8964026;Reactome: R-HSA-8856828;Reactome: R-HSA-432142;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938	"Post-translational protein phosphorylation";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron assembly";"VLDL assembly";"LDL clearance";"Chylomicron remodeling";"Scavenging by Class B Receptors";"VLDL clearance";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Scavenging by Class H Receptors";"Scavenging by Class F Receptors";"Chylomicron clearance";"Clathrin-mediated endocytosis";"Platelet sensitization by LDL";"LDL remodeling";"Regulation of TLR by endogenous ligand"
XP_017002647.2	5	KEGG: 00280+1.2.4.4;Reactome: R-HSA-70895;KEGG: 00640+1.2.4.4;MetaCyc: PWY-5046;Reactome: R-HSA-389661	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation"
XP_044251996.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_017003736.1	10	Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-202424	"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Neddylation";"Downstream TCR signaling"
XP_016992339.2	2	Reactome: R-HSA-446193;Reactome: R-HSA-5633231	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)"
XP_044250463.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_017012924.2	4	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522;Reactome: R-HSA-379726	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation"
XP_016993688.2	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_016995150.2	3	Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_016996073.2	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_044250206.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_017014997.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044251659.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_017002861.2	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_017011197.2	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016997210.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_016992483.2	9	Reactome: R-HSA-69017;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-68689;Reactome: R-HSA-1362277;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68949	"CDK-mediated phosphorylation and removal of Cdc6";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"CDC6 association with the ORC:origin complex";"Transcription of E2F targets under negative control by DREAM complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin"
XP_044249167.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_016992768.2	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_017002312.2	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_017004440.2	4	Reactome: R-HSA-8964011;Reactome: R-HSA-3359463;Reactome: R-HSA-196741;Reactome: R-HSA-3359462	"HDL clearance";"Defective CUBN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective AMN causes hereditary megaloblastic anemia 1"
XP_017005274.2	4	Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-2586552	"Growth hormone receptor signaling";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin"
XP_044249187.1	3	Reactome: R-HSA-2980766;Reactome: R-HSA-4419969;Reactome: R-HSA-2995383	"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation"
XP_016993913.2	5	KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2	"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)"
XP_017003271.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016994624.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_016996929.2	7	Reactome: R-HSA-5693565;MetaCyc: PWY-7511;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-983168;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Protein ubiquitination";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins"
XP_016998872.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_017002763.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_017007597.2	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_044248720.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_017001290.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_017008753.2	4	MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040;MetaCyc: PWY-8072	"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Ansatrienin biosynthesis";"Alanine racemization"
XP_017011701.2	17	Reactome: R-HSA-74217;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-6644;MetaCyc: PWY-7179;MetaCyc: PWY-6620;KEGG: 00230+2.4.2.1;MetaCyc: PWY-4202;MetaCyc: PWY-5695;MetaCyc: PWY-7179-1;MetaCyc: PWY-6627;Reactome: R-HSA-6798695;KEGG: 00240+2.4.2.1;MetaCyc: PWY-5532;Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-6611	"Purine salvage";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage III";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation I";"Guanine and guanosine salvage";"Purine metabolism";"Arsenate detoxification I (mammalian)";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation II";"Salinosporamide A biosynthesis";"Neutrophil degranulation";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Purine catabolism";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage V"
XP_017009141.2	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016994822.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_017011388.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_016994325.2	5	Reactome: R-HSA-2426168;Reactome: R-HSA-191273;KEGG: 00900+2.7.4.2;MetaCyc: PWY-922;MetaCyc: PWY-7391	"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)"
XP_017012939.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_017000297.1	56	Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-174184	"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_017011417.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016996766.2	7	MetaCyc: PWY-5129;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7838;MetaCyc: PWY-7841;MetaCyc: PWY-7836;MetaCyc: PWY-7839;Reactome: R-HSA-1660662	"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism"
XP_016998891.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_017008556.2	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_044251478.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_044251456.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_017011689.2	7	MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-7445	"Betanidin degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation"
XP_017004655.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_017010755.2	3	Reactome: R-HSA-204174;Reactome: R-HSA-8963684;Reactome: R-HSA-156590	"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism";"Glutathione conjugation"
XP_017014209.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_044250142.1	5	Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-109704;Reactome: R-HSA-1257604	"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PI3K Cascade";"PIP3 activates AKT signaling"
XP_044248696.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017010436.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016999654.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_017005352.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_017001082.2	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
XP_017015381.2	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_017000562.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_017010204.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_016994666.2	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_016999916.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_017007902.2	4	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454;KEGG: 00513+2.4.1.261	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Various types of N-glycan biosynthesis"
XP_044249335.1	10	KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23	"Other glycan degradation";"MPS VII - Sly syndrome";"Galactose metabolism";"Hyaluronan uptake and degradation";"HS-GAG degradation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Sphingolipid metabolism"
XP_017011907.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_017004043.2	31	MetaCyc: PWY-5367;MetaCyc: PWY-6113;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6282;MetaCyc: PWY-5971;Reactome: R-HSA-75105;MetaCyc: PWY-7664;MetaCyc: PWY-5966-1;MetaCyc: PWY-8012;MetaCyc: PWY-7858;MetaCyc: PWY-5989;MetaCyc: PWY-7663;MetaCyc: PWY-8047;Reactome: R-HSA-2426168;MetaCyc: PWY-7723;Reactome: R-HSA-199220;Reactome: R-HSA-163765;MetaCyc: PWYG-321;MetaCyc: PWY-5994;MetaCyc: PWY-8049;MetaCyc: PWY-5366;MetaCyc: PWY-5147;MetaCyc: PWY-6799;MetaCyc: PWY-4381;Reactome: R-HSA-9029558;MetaCyc: PWY-5142;MetaCyc: PWY-7746;MetaCyc: PWY-6519;MetaCyc: PWY-7388;MetaCyc: PWY-5973	"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"Biotin metabolism";"Fatty acid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Mupirocin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Bryostatin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Bacterial bioluminescence";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Pederin biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Mycobacterial sulfolipid biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Cis-vaccenate biosynthesis"
XP_017016080.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016994335.2	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_044252151.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_017006713.2	4	MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32	"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism"
XP_044248752.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017010197.2	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_017010675.2	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_017002500.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016997481.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017014723.2	2	Reactome: R-HSA-2151201;KEGG: 00970+6.1.1.14	"Transcriptional activation of mitochondrial biogenesis";"Aminoacyl-tRNA biosynthesis"
XP_017002498.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017011990.2	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_016999837.2	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_017015151.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118	"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors"
XP_044250684.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
XP_044250242.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044249210.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044249482.1	42	Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-69473;Reactome: R-HSA-3214858;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-5693571;Reactome: R-HSA-1912408;Reactome: R-HSA-3214842;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-1221632;Reactome: R-HSA-977225;Reactome: R-HSA-2559586;Reactome: R-HSA-110329;Reactome: R-HSA-9610379;Reactome: R-HSA-5625886;Reactome: R-HSA-171306;Reactome: R-HSA-8936459;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-5693607;Reactome: R-HSA-427389;Reactome: R-HSA-912446;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-8939236;Reactome: R-HSA-3214841	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"G2/M DNA damage checkpoint";"RMTs methylate histone arginines";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Nonhomologous End-Joining (NHEJ)";"Pre-NOTCH Transcription and Translation";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Meiotic synapsis";"Amyloid fiber formation";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"HCMV Late Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Packaging Of Telomere Ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"PRC2 methylates histones and DNA";"HCMV Early Events";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"DNA methylation";"Estrogen-dependent gene expression";"Processing of DNA double-strand break ends";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic recombination";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PKMTs methylate histone lysines"
XP_017000314.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_017008996.2	4	Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_016994699.2	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_044248510.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_017005046.2	13	Reactome: R-HSA-196757;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+6.3.4.3;MetaCyc: PWY-3841;MetaCyc: PWY-6613;MetaCyc: PWY-2161;MetaCyc: PWY-5030;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-7909;MetaCyc: PWY-5497;KEGG: 00720+6.3.4.3	"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate polyglutamylation";"L-histidine degradation III";"Folate transformations I";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes"
XP_017002001.2	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_016995921.1	58	Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-5689901;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-8939902	"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Metalloprotease DUBs";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Separation of Sister Chromatids";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity"
XP_017005139.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_017006209.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_017002293.2	7	KEGG: 00030+3.1.1.31;MetaCyc: PWY-5514;MetaCyc: PWY-6855;Reactome: R-HSA-71336;KEGG: 00520+3.5.99.6;MetaCyc: PWY-8004;MetaCyc: PWY-6906	"Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Pentose phosphate pathway";"Amino sugar and nucleotide sugar metabolism";"Entner-Doudoroff pathway I";"Chitin derivatives degradation"
XP_017013975.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_017004298.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016998985.2	9	MetaCyc: PWY-6385;Reactome: R-HSA-5633231;MetaCyc: PWY-6471;Reactome: R-HSA-446193;KEGG: 00550+2.4.1.227;MetaCyc: PWY-6470;MetaCyc: PWY-5265;KEGG: 00513+2.4.1.141;KEGG: 00510+2.4.1.141	"Peptidoglycan biosynthesis III (mycobacteria)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis II (staphylococci)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_017008021.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044251998.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_017000442.2	5	Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-201681	"Degradation of AXIN";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Protein ubiquitination";"TCF dependent signaling in response to WNT"
XP_044251551.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017011660.2	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_017008784.2	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_017008762.1	10	MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00562+5.3.1.1;KEGG: 00051+5.3.1.1;Reactome: R-HSA-70171;KEGG: 00710+5.3.1.1;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-1042	"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Inositol phosphate metabolism";"Fructose and mannose metabolism";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Glycolysis IV (plant cytosol)"
XP_044252077.1	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
XP_017009153.2	4	MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-5737	"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis"
XP_017012330.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016998514.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_017000451.2	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_017010420.2	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_017002086.2	3	Reactome: R-HSA-1810476;Reactome: R-HSA-933542;Reactome: R-HSA-445989	"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_017012249.2	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_016999643.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_017014914.2	10	KEGG: 00650+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7524;MetaCyc: PWY-7391;MetaCyc: PWY-7571;MetaCyc: PWY-922;KEGG: 00072+2.3.3.10;KEGG: 00900+2.3.3.10	"Butanoate metabolism";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Valine, leucine and isoleucine degradation";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Ferrichrome A biosynthesis";"Mevalonate pathway I";"Synthesis and degradation of ketone bodies";"Terpenoid backbone biosynthesis"
XP_017008960.2	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_016996269.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_017002353.2	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_017003610.2	10	Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-200425;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-2151209;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Carnitine metabolism";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_017000282.2	4	Reactome: R-HSA-4719360;Reactome: R-HSA-162699;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374	"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)"
XP_017013598.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016992507.2	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-73780	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation"
XP_017013161.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_017011124.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017012578.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017012594.2	14	MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5972;Reactome: R-HSA-75876	"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_016993214.2	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_017004254.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017013332.1	33	Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-69656;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-69231;Reactome: R-HSA-69273;Reactome: R-HSA-6781827;Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-69202;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-5696395;Reactome: R-HSA-8939236;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-73772	"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin A:Cdk2-associated events at S phase entry";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Cyclin D associated events in G1";"Cyclin A/B1/B2 associated events during G2/M transition";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Cyclin E associated events during G1/S transition";"mRNA Capping";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of Incision Complex in GG-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Promoter Escape"
XP_017012935.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016996720.2	5	MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653	"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_017009408.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_016999645.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044249119.1	14	Reactome: R-HSA-380259;Reactome: R-HSA-141444;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2467813;Reactome: R-HSA-8854518;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Separation of Sister Chromatids";"AURKA Activation by TPX2";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes"
XP_016999338.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017007174.2	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_016998023.1	3	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_017008014.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9633012	"Selenocysteine synthesis";"Viral mRNA Translation";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_016995498.2	7	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.15;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379716;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Cytosolic tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol"
XP_044248830.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-381676	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_044248822.1	7	MetaCyc: PWY-7039;Reactome: R-HSA-1483148;KEGG: 00565+3.1.4.4;Reactome: R-HSA-2029485;Reactome: R-HSA-1483166;MetaCyc: PWY-3561;KEGG: 00564+3.1.4.4	"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG";"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Synthesis of PA";"Choline biosynthesis III";"Glycerophospholipid metabolism"
XP_017010751.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017007547.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_017007654.2	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-381038	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes"
XP_017007639.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_017012318.1	3	Reactome: R-HSA-611105;Reactome: R-HSA-1268020;Reactome: R-HSA-6799198	"Respiratory electron transport";"Mitochondrial protein import";"Complex I biogenesis"
XP_016992533.2	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_016997918.2	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_044249359.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016993964.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016999254.2	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_017015904.2	2	Reactome: R-HSA-5654726;Reactome: R-HSA-190373	"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation"
XP_044249417.1	42	Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-69473;Reactome: R-HSA-3214858;Reactome: R-HSA-5693571;Reactome: R-HSA-3214842;Reactome: R-HSA-1912408;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-2559580;Reactome: R-HSA-1221632;Reactome: R-HSA-977225;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-110329;Reactome: R-HSA-5625886;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-171306;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-9616222;Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-912446;Reactome: R-HSA-427389;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-5693607;Reactome: R-HSA-3214841;Reactome: R-HSA-8939236	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"G2/M DNA damage checkpoint";"RMTs methylate histone arginines";"Nonhomologous End-Joining (NHEJ)";"HDMs demethylate histones";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Oxidative Stress Induced Senescence";"Meiotic synapsis";"Amyloid fiber formation";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"Cleavage of the damaged pyrimidine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Packaging Of Telomere Ends";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"Transcriptional regulation of granulopoiesis";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"Transcriptional regulation by small RNAs";"DNA methylation";"Estrogen-dependent gene expression";"HATs acetylate histones";"Meiotic recombination";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"Processing of DNA double-strand break ends";"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_016998651.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_017003793.2	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_016995272.2	18	MetaCyc: PWY-7184;MetaCyc: PWY-7221;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7205;MetaCyc: PWY-7224;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7176;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Purine metabolism"
XP_044250163.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_017014897.2	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016997422.2	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
XP_017015079.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016994730.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_017012878.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017011180.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016994459.2	3	MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531	"Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus"
XP_016999504.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-114516;Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13	"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system"
XP_017006453.1	11	KEGG: 00720+1.1.1.42;MetaCyc: PWY-6549;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-7268;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-7254;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7124	"Carbon fixation pathways in prokaryotes";"L-glutamine biosynthesis III";"Glutathione metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Ethylene biosynthesis V (engineered)"
XP_017010419.2	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_017015364.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044251034.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_016996151.2	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_017013874.2	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_016997463.2	1	Reactome: R-HSA-3295583	"TRP channels"
XP_017011407.2	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_016999579.2	5	KEGG: 00720+1.5.1.20;MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.20	"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Metabolism of folate and pterines";"Folate transformations II (plants)";"One carbon pool by folate"
XP_044249314.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017000774.2	2	KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270	"Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate"
XP_017009946.2	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_016994913.2	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_016999082.2	3	KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_016995640.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016994795.2	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_044251750.1	10	MetaCyc: PWY-7571;MetaCyc: PWY-922;KEGG: 00072+2.3.3.10;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-7524;KEGG: 00900+2.3.3.10;KEGG: 00650+2.3.3.10;MetaCyc: PWY-6174;Reactome: R-HSA-1989781	"Ferrichrome A biosynthesis";"Mevalonate pathway I";"Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis";"Butanoate metabolism";"Mevalonate pathway II (archaea)";"PPARA activates gene expression"
XP_017003027.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_017005143.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_044250098.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_017012712.2	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016999639.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_017016140.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828	"MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis"
XP_017006853.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_016998028.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_044248997.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_017001669.2	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_016995444.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016998875.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_044249454.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_017008476.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_016992586.2	22	Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-9648025;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-6811558;Reactome: R-HSA-389513;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5673000;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716	"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"EML4 and NUDC in mitotic spindle formation";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CTLA4 inhibitory signaling";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RAF activation";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin"
XP_017013960.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016999894.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017015942.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044249862.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_017001167.1	5	MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism"
XP_016995617.2	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_044248492.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_017016075.1	19	Reactome: R-HSA-5626467;Reactome: R-HSA-8964616;Reactome: R-HSA-983231;Reactome: R-HSA-418885;Reactome: R-HSA-194840;Reactome: R-HSA-5627123;Reactome: R-HSA-5663213;Reactome: R-HSA-389359;Reactome: R-HSA-5625970;Reactome: R-HSA-182971;Reactome: R-HSA-5687128;Reactome: R-HSA-3928662;Reactome: R-HSA-8950505;Reactome: R-HSA-5663220;Reactome: R-HSA-2029482;Reactome: R-HSA-428543;Reactome: R-HSA-114604;Reactome: R-HSA-525793;Reactome: R-HSA-4420097	"RHO GTPases activate IQGAPs";"G beta:gamma signalling through CDC42";"Factors involved in megakaryocyte development and platelet production";"DCC mediated attractive signaling";"Rho GTPase cycle";"RHO GTPases activate PAKs";"RHO GTPases Activate WASPs and WAVEs";"CD28 dependent Vav1 pathway";"RHO GTPases activate KTN1";"EGFR downregulation";"MAPK6/MAPK4 signaling";"EPHB-mediated forward signaling";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases Activate Formins";"Regulation of actin dynamics for phagocytic cup formation";"Inactivation of CDC42 and RAC1";"GPVI-mediated activation cascade";"Myogenesis";"VEGFA-VEGFR2 Pathway"
XP_017009992.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_017007800.1	18	MetaCyc: PWY-7197;MetaCyc: PWY-7176;MetaCyc: PWY-7226;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-7210;MetaCyc: PWY-7220;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7205;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7227	"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_016999781.2	3	Reactome: R-HSA-1369062;Reactome: R-HSA-9029569;Reactome: R-HSA-8964058	"ABC transporters in lipid homeostasis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling"
XP_017012619.2	13	Reactome: R-HSA-6798695;Reactome: R-HSA-5689896;Reactome: R-HSA-110320;Reactome: R-HSA-382556;Reactome: R-HSA-3371511;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399;Reactome: R-HSA-8866654;Reactome: R-HSA-5678895;Reactome: R-HSA-8876725;Reactome: R-HSA-532668	"Neutrophil degranulation";"Ovarian tumor domain proteases";"Translesion Synthesis by POLH";"ABC-family proteins mediated transport";"HSF1 activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Josephin domain DUBs";"Aggrephagy";"E3 ubiquitin ligases ubiquitinate target proteins";"Defective CFTR causes cystic fibrosis";"Protein methylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_016995670.2	16	Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-176407;Reactome: R-HSA-174184	"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_044251362.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_017013293.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_044249626.1	42	Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-8936459;Reactome: R-HSA-171306;Reactome: R-HSA-9616222;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-5693607;Reactome: R-HSA-912446;Reactome: R-HSA-427389;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-8939236;Reactome: R-HSA-3214841;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-3214858;Reactome: R-HSA-69473;Reactome: R-HSA-201722;Reactome: R-HSA-3214815;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-2299718;Reactome: R-HSA-5250924;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-110329;Reactome: R-HSA-9610379;Reactome: R-HSA-5625886;Reactome: R-HSA-977225;Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-3214842;Reactome: R-HSA-110330;Reactome: R-HSA-110331	"PRC2 methylates histones and DNA";"HCMV Early Events";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Packaging Of Telomere Ends";"Transcriptional regulation of granulopoiesis";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Processing of DNA double-strand break ends";"Meiotic recombination";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PKMTs methylate histone lysines";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"Estrogen-dependent gene expression";"DNA methylation";"RMTs methylate histone arginines";"G2/M DNA damage checkpoint";"Formation of the beta-catenin:TCF transactivating complex";"HDACs deacetylate histones";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Condensation of Prophase Chromosomes";"B-WICH complex positively regulates rRNA expression";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cleavage of the damaged pyrimidine";"HCMV Late Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Amyloid fiber formation";"Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine"
XP_017002497.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044248995.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105	"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation"
XP_044250717.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_044251313.1	19	Reactome: R-HSA-3000497;Reactome: R-HSA-3000484;Reactome: R-HSA-8964026;Reactome: R-HSA-8856828;Reactome: R-HSA-432142;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-8963901;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423;Reactome: R-HSA-8957275;Reactome: R-HSA-8856825;Reactome: R-HSA-3000480	"Scavenging by Class H Receptors";"Scavenging by Class F Receptors";"Chylomicron clearance";"Clathrin-mediated endocytosis";"Platelet sensitization by LDL";"LDL remodeling";"Regulation of TLR by endogenous ligand";"Chylomicron remodeling";"LDL clearance";"VLDL clearance";"Scavenging by Class B Receptors";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron assembly";"VLDL assembly";"Post-translational protein phosphorylation";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class A Receptors"
XP_044248707.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017012751.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044251995.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_017011381.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016993129.2	8	Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-174411	"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Polymerase switching";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere"
XP_017007948.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044250175.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016993037.2	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_016993304.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_044251623.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-69656	"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry"
XP_044251711.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_017002320.1	6	Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253	"Triglyceride catabolism";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Circadian Clock"
XP_017011181.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_017015405.2	6	MetaCyc: PWY-6118;MetaCyc: PWY-4261;MetaCyc: PWY-6952;Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166	"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerophospholipid metabolism";"Synthesis of PA"
XP_017014913.2	10	MetaCyc: PWY-7524;MetaCyc: PWY-7391;KEGG: 00280+2.3.3.10;MetaCyc: PWY-922;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7571;KEGG: 00900+2.3.3.10;KEGG: 00650+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-6174	"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Valine, leucine and isoleucine degradation";"Mevalonate pathway I";"Synthesis and degradation of ketone bodies";"Ferrichrome A biosynthesis";"Terpenoid backbone biosynthesis";"Butanoate metabolism";"PPARA activates gene expression";"Mevalonate pathway II (archaea)"
XP_017006459.2	5	Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827	"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_017005528.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_017013827.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_016995115.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016995238.2	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_044251589.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017013559.2	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_044252152.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016994810.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017005295.2	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_044251774.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_044251897.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_017013040.2	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_017008385.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016995947.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044251285.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_017009794.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017002607.2	6	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_017002057.2	5	Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_017007863.2	20	KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7340;MetaCyc: PWY-735;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-7007;MetaCyc: PWY-7288;MetaCyc: PWY-7291;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-6837;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7858;MetaCyc: PWY-7574	"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II"
XP_017000326.1	3	Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514	"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane"
XP_017010165.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_016992588.2	22	Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-5675221;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-432142;Reactome: R-HSA-9648025;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-5673000;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-2500257;Reactome: R-HSA-6811558;Reactome: R-HSA-196299;Reactome: R-HSA-5467337	"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Negative regulation of MAPK pathway";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Platelet sensitization by LDL";"EML4 and NUDC in mitotic spindle formation";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"Resolution of Sister Chromatid Cohesion";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding"
XP_044251012.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044252146.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_017007579.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016994327.2	3	Reactome: R-HSA-2514859;Reactome: R-HSA-8876725;KEGG: 00310+2.1.1.60	"Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation";"Lysine degradation"
XP_016999846.2	5	MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism"
XP_016997153.1	7	KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22	"Glutathione metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism"
XP_017000589.2	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_017012008.2	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_016994048.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_017008758.2	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_017010156.2	5	KEGG: 00785+2.3.1.181;KEGG: 00785+6.3.1.20;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661	"Lipoic acid metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation"
XP_016994708.2	7	KEGG: 00480+6.3.2.2;MetaCyc: PWY-6840;Reactome: R-HSA-174403;MetaCyc: PWY-8043;Reactome: R-HSA-5578999;KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255	"Glutathione metabolism";"Homoglutathione biosynthesis";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)"
XP_017010167.1	56	Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway"
XP_044251745.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_017008477.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_016992629.2	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_044251266.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_044252198.1	10	Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243	"Signal transduction by L1";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_017013765.2	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_017008025.2	15	Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616	"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_044251525.1	3	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339;Reactome: R-HSA-9609523	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016999733.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_017013155.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_017000397.2	27	Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response"
XP_016995611.2	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_016997170.2	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_017015792.2	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_016995535.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_016996204.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_017013713.2	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_017013424.2	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism"
XP_016997872.2	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_016992636.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975957	"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_016999471.2	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_016998757.2	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_017005717.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_017015735.2	7	Reactome: R-HSA-1268020;Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-2151201;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2	"Mitochondrial protein import";"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"Cristae formation";"Transcriptional activation of mitochondrial biogenesis";"ATP biosynthesis";"Photosynthesis"
XP_017013606.2	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016993534.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_016998515.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_044249655.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_044251315.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_017006356.2	7	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_016993113.2	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1679131;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-2132295	"Neutrophil degranulation";"Trafficking and processing of endosomal TLR";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"MHC class II antigen presentation"
XP_016998901.2	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_017001011.2	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_016998721.2	3	Reactome: R-HSA-1369062;Reactome: R-HSA-8964058;Reactome: R-HSA-9029569	"ABC transporters in lipid homeostasis";"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_017011201.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016999428.2	6	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1"
XP_016998560.1	56	Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"Separation of Sister Chromatids";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_016992907.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_017007833.2	11	Reactome: R-HSA-8847993;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-6785631;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-1227986;Reactome: R-HSA-1257604;Reactome: R-HSA-1963642	"ERBB2 Activates PTK6 Signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2";"PIP3 activates AKT signaling";"PI3K events in ERBB2 signaling"
XP_017015928.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_017010778.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_017001402.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling"
XP_017006631.2	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_017009349.2	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_017014722.2	8	Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68867	"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex"
XP_017002065.2	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_016998837.2	4	Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814	"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes"
XP_044249976.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_044250642.1	5	MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16	"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism"
XP_017013160.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016996072.2	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_017002499.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017015940.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_017007542.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016998945.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017012107.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_044250109.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_017001796.1	23	Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-500657;Reactome: R-HSA-4086398;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-432040;Reactome: R-HSA-392170;Reactome: R-HSA-416482;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-202040;Reactome: R-HSA-456926;Reactome: R-HSA-9009391;Reactome: R-HSA-420092;Reactome: R-HSA-8964616;Reactome: R-HSA-418217;Reactome: R-HSA-416476	"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"Presynaptic function of Kainate receptors";"Ca2+ pathway";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"Vasopressin regulates renal water homeostasis via Aquaporins";"ADP signalling through P2Y purinoceptor 12";"G alpha (12/13) signalling events";"G alpha (z) signalling events";"G alpha (s) signalling events";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G-protein activation";"Thrombin signalling through proteinase activated receptors (PARs)";"Extra-nuclear estrogen signaling";"Glucagon-type ligand receptors";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events"
XP_044249408.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_017012459.2	7	Reactome: R-HSA-8943724;Reactome: R-HSA-9029569;Reactome: R-HSA-3214842;Reactome: R-HSA-3214815;Reactome: R-HSA-983231;Reactome: R-HSA-5625886;Reactome: R-HSA-9018519	"Regulation of PTEN gene transcription";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDMs demethylate histones";"HDACs deacetylate histones";"Factors involved in megakaryocyte development and platelet production";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Estrogen-dependent gene expression"
XP_017011152.2	8	Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8	"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism"
XP_016993507.2	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_017008378.2	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_044251603.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016992776.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016994042.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016999559.2	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_017011227.2	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_016994530.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_044251452.1	5	KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73614;Reactome: R-HSA-73621	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage";"Pyrimidine catabolism"
XP_017008981.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017003025.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_017012552.2	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_017011992.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044251247.1	12	Reactome: R-HSA-429947;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-450408;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-166208	"Deadenylation of mRNA";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"ISG15 antiviral mechanism";"mTORC1-mediated signalling"
XP_017005189.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016999138.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044251442.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_016993457.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_044252150.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_017013577.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_017006692.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_016997603.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_017011723.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_017001392.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_016993807.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs"
XP_044249962.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_017007924.2	20	KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-6837;MetaCyc: PWY-7854;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7606;MetaCyc: PWY-7858;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7340;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-7007	"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)"
XP_016993700.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016996128.2	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_016995062.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_044251582.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_017009802.2	18	MetaCyc: PWY-6638;MetaCyc: PWY-7383;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00960+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00710+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-5913;MetaCyc: PWY-7117	"Sulfolactate degradation III";"Anaerobic energy metabolism (invertebrates, cytosol)";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine biosynthesis";"Tyrosine metabolism";"Alanine, aspartate and glutamate metabolism";"Novobiocin biosynthesis";"Phenylalanine metabolism";"Coenzyme M biosynthesis II";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"(R)-cysteate degradation";"Partial TCA cycle (obligate autotrophs)";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_044251121.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_017015646.2	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_017008276.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016995571.2	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_016998690.2	14	MetaCyc: PWY-8041;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7036	"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II"
XP_017011433.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017015182.2	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_016995539.2	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_017008117.2	4	Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-352230	"Basigin interactions";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane"
XP_017010134.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017008853.1	12	Reactome: R-HSA-193692;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-1251985;Reactome: R-HSA-982772;Reactome: R-HSA-5362798;Reactome: R-HSA-1442490;Reactome: R-HSA-75893	"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Nuclear signaling by ERBB4";"Growth hormone receptor signaling";"Release of Hh-Np from the secreting cell";"Collagen degradation";"TNF signaling"
XP_044249315.1	14	Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-75955	"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation"
XP_017011691.2	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_016998334.2	3	KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9	"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation";"One carbon pool by folate"
XP_016996951.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399	"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Aggrephagy"
XP_016995850.2	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_044249217.1	10	Reactome: R-HSA-1855191;Reactome: R-HSA-1855167;MetaCyc: PWY-4661;MetaCyc: PWY-6372;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-6362;MetaCyc: PWY-6369	"Synthesis of IPs in the nucleus";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis"
XP_017007937.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_017006372.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_017011904.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_017006917.2	5	Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_017011163.1	40	Reactome: R-HSA-72163;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-6782135;Reactome: R-HSA-6803529;Reactome: R-HSA-72203;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-5617472;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-5578749;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-72165;Reactome: R-HSA-5601884;Reactome: R-HSA-203927;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-167162	"mRNA Splicing - Major Pathway";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Dual incision in TC-NER";"FGFR2 alternative splicing";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Transcriptional regulation by small RNAs";"mRNA Capping";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Minor Pathway";"PIWI-interacting RNA (piRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II HIV Promoter Escape"
XP_017009255.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_017009758.2	6	Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_017015135.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_017010966.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_017004006.2	9	Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167162	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape"
XP_016997277.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016993080.2	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_017001074.2	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016998974.2	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_044251502.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_017012248.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176974	"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Unwinding of DNA"
XP_017001111.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism"
XP_017012603.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016993000.1	5	KEGG: 00230+2.7.4.10;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219	"Purine metabolism";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis"
XP_016999588.2	3	Reactome: R-HSA-5657562;Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3	"Essential fructosuria";"Fructose catabolism";"Fructose and mannose metabolism"
XP_016992628.2	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_017006690.2	3	MetaCyc: PWY-7892;Reactome: R-HSA-6787450;MetaCyc: PWY-7887	"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation"
XP_017010568.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_017015987.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_044252084.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_017011184.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_017012519.2	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_016993339.2	8	Reactome: R-HSA-373080;Reactome: R-HSA-8856828;Reactome: R-HSA-4086398;Reactome: R-HSA-5340588;Reactome: R-HSA-4641263;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-4608870	"Class B/2 (Secretin family receptors)";"Clathrin-mediated endocytosis";"Ca2+ pathway";"RNF mutants show enhanced WNT signaling and proliferation";"Regulation of FZD by ubiquitination";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Asymmetric localization of PCP proteins"
XP_017009680.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_017013800.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_044248581.1	5	MetaCyc: PWY-7511;Reactome: R-HSA-381038;Reactome: R-HSA-901032;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768	"Protein ubiquitination";"XBP1(S) activates chaperone genes";"ER Quality Control Compartment (ERQC)";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_017011719.1	14	MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-7589	"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_017001005.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044250535.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_017015201.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811440	"Trafficking of GluR2-containing AMPA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network"
XP_016994845.2	13	Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902	"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation"
XP_017015894.2	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_016995017.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_017010841.2	7	KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25	"Streptomycin biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_017009519.2	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016996058.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_017000629.2	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_017009451.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490	"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation"
XP_017008334.2	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_016995066.2	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_017009232.2	34	Reactome: R-HSA-8939236;Reactome: R-HSA-5696395;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-69202;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-73762;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-69273;Reactome: R-HSA-6781827;Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-167152;Reactome: R-HSA-69231;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-69656;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-167246	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"mRNA Capping";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"Cyclin E associated events during G1/S transition";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Cyclin A/B1/B2 associated events during G2/M transition";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Cyclin D associated events in G1";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript"
XP_016998103.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044251061.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_017002563.2	16	Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis"
XP_017005452.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016995244.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-186763;Reactome: R-HSA-5218921;Reactome: R-HSA-5658442	"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Downstream signal transduction";"VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs"
XP_016997400.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_016997067.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044250879.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_044251500.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_017004870.2	14	MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7411	"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)"
XP_016999684.2	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_017010618.2	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_017013724.1	6	Reactome: R-HSA-1660499;MetaCyc: PWY-6580;KEGG: 04070+3.1.3.64+3.1.3.95;MetaCyc: PWY-6367;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.64+3.1.3.95	"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol biosynthesis I (bacteria)";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation";"Inositol phosphate metabolism"
XP_044250992.1	5	Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;Reactome: R-HSA-197264;MetaCyc: PWY-5381	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)"
XP_017004680.1	6	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_044250036.1	4	Reactome: R-HSA-112311;Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism";"Synthesis of PC"
XP_016998519.2	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_017005187.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_017012006.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_017012192.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_017005298.2	6	Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6364;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism"
XP_016994738.2	33	Reactome: R-HSA-209543;Reactome: R-HSA-168638;Reactome: R-HSA-933541;Reactome: R-HSA-937042;Reactome: R-HSA-205043;Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-933542;Reactome: R-HSA-937039;Reactome: R-HSA-937072;Reactome: R-HSA-6811558;Reactome: R-HSA-168927;Reactome: R-HSA-193692;Reactome: R-HSA-166058;Reactome: R-HSA-975138;Reactome: R-HSA-5607764;Reactome: R-HSA-975871;Reactome: R-HSA-450321;Reactome: R-HSA-1257604;Reactome: R-HSA-5689880;Reactome: R-HSA-450302;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-975155;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-9020702;Reactome: R-HSA-9014325;Reactome: R-HSA-975163;Reactome: R-HSA-209560;Reactome: R-HSA-937041;Reactome: R-HSA-5689896;Reactome: R-HSA-975110	"p75NTR recruits signalling complexes";"NOD1/2 Signaling Pathway";"TRAF6 mediated IRF7 activation";"IRAK2 mediated activation of TAK1 complex";"NRIF signals cell death from the nucleus";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"TRAF6 mediated NF-kB activation";"IRAK1 recruits IKK complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"Regulated proteolysis of p75NTR";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"CLEC7A (Dectin-1) signaling";"MyD88 cascade initiated on plasma membrane";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"PIP3 activates AKT signaling";"Ub-specific processing proteases";"activated TAK1 mediates p38 MAPK activation";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"MyD88 dependent cascade initiated on endosome";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"Interleukin-1 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"NF-kB is activated and signals survival";"IKK complex recruitment mediated by RIP1";"Ovarian tumor domain proteases";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling"
XP_044249409.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_017005044.2	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_016999299.2	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-73780	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation"
XP_016994835.2	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_016995439.2	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_016998011.2	5	Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757	"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation"
XP_044251778.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_017014344.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017002624.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_017016241.2	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_016997455.2	8	MetaCyc: PWY-4983;KEGG: 00250+6.3.4.5;MetaCyc: PWY-5154;KEGG: 00220+6.3.4.5;MetaCyc: PWY-5;MetaCyc: PWY-7400;MetaCyc: PWY-4984;Reactome: R-HSA-70635	"Nitric oxide biosynthesis II (mammals)";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Arginine biosynthesis";"Canavanine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Urea cycle";"Urea cycle"
XP_016993075.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016996489.2	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_016995528.2	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_016999790.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044250833.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_017014484.2	4	KEGG: 00450+6.1.1.10;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716	"Selenocompound metabolism";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_017002549.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044249174.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_017009251.2	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_044251742.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016999380.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044250854.1	14	Reactome: R-HSA-3371497;Reactome: R-HSA-1632852;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-5620924;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6807878	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Macroautophagy";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Intraflagellar transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-mediated anterograde transport"
XP_017004812.2	8	Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_044251010.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_016993212.2	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_016994896.2	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_017001914.2	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_044248981.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017012938.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_017008020.2	4	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex"
XP_017014743.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_016994993.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_017012907.2	10	MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559	"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Glutathione metabolism";"Glutathione degradation (DUG pathway"
XP_017011536.2	11	Reactome: R-HSA-74259;MetaCyc: PWY-6607;MetaCyc: PWY-6596;MetaCyc: PWY-5497;MetaCyc: PWY-6606;MetaCyc: PWY-6608;MetaCyc: PWY-6538;Reactome: R-HSA-8851680;KEGG: 00230+1.17.1.4;MetaCyc: PWY-5695;MetaCyc: PWY-6999	"Purine catabolism";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Caffeine degradation III (bacteria, via demethylation)";"Butyrophilin (BTN) family interactions";"Purine metabolism";"Inosine 5'-phosphate degradation";"Theophylline degradation"
XP_044251200.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_017004044.2	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_017003606.2	10	Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-200425;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-163680	"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"Carnitine metabolism";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity"
XP_017010682.2	3	Reactome: R-HSA-156590;Reactome: R-HSA-204174;Reactome: R-HSA-8963684	"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism"
XP_016993333.2	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016995239.2	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_016998968.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs"
XP_017010940.2	2	Reactome: R-HSA-1660662;Reactome: R-HSA-1663150	"Glycosphingolipid metabolism";"The activation of arylsulfatases"
XP_016993835.2	5	Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310	"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Fanconi Anemia Pathway"
XP_017005656.2	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_017012881.2	9	MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18	"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione conjugation";"Drug metabolism - other enzymes"
XP_017003586.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017008764.2	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_017011788.2	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_016994729.2	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_016994041.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044249070.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_017006822.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_017008195.2	7	MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23;KEGG: 00240+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7790	"UMP biosynthesis III";"UMP biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis II"
XP_017005512.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_017013249.2	7	KEGG: 00550+2.7.8.13;MetaCyc: PWY-6470;KEGG: 00510+2.7.8.15;Reactome: R-HSA-4549356;MetaCyc: PWY-5265;Reactome: R-HSA-446193;MetaCyc: PWY-6471	"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"N-Glycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)"
XP_017011783.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016997267.2	5	Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2	"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism"
XP_016996815.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_016998765.2	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016994299.1	6	MetaCyc: PWY-5663;MetaCyc: PWY-5664;KEGG: 00790+4.2.3.12;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-6983	"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis"
XP_016999839.2	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_017014704.2	12	MetaCyc: PWY-6277;Reactome: R-HSA-196780;KEGG: 00230+6.3.4.13;KEGG: 00970+2.1.2.9;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.9;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6122;MetaCyc: PWY-6613;KEGG: 00670+2.1.2.2;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6121	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Biotin transport and metabolism";"Purine metabolism";"Aminoacyl-tRNA biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_016994039.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044248594.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017005474.1	4	Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_017013153.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_017006668.1	6	KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204	"Phosphatidylinositol signaling system";"Rho GTPase cycle";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol"
XP_044249865.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016992610.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_017015656.2	3	KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664;MetaCyc: PWY-7999	"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K";"Vitamin K-epoxide cycle"
XP_016993294.2	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_017006339.1	9	KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;MetaCyc: PWY-7902;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-6118	"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle"
XP_017015519.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017002657.2	5	Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_017007055.2	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_016992771.2	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_016996059.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_017011722.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044249950.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_017015407.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017007518.2	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016995374.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016994727.2	4	Reactome: R-HSA-964975;MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5	"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism"
XP_016993476.2	27	Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-168271	"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus"
XP_016999155.2	3	MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+1.3.3.4	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_017011886.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_017013619.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_017015591.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017014322.2	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_016996549.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_017000976.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_017016275.2	3	Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1	"Phenylalanine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism"
XP_016993416.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044251923.1	10	Reactome: R-HSA-427413;Reactome: R-HSA-9022538;Reactome: R-HSA-400206;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-8936459;Reactome: R-HSA-9022702	"NoRC negatively regulates rRNA expression";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of lipid metabolism by PPARalpha";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands"
XP_016999697.2	8	Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-6781823;Reactome: R-HSA-5689880	"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Regulation of PTEN localization";"Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases"
XP_017012748.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions"
XP_017003082.2	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_044250063.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_016999433.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044250788.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_017014115.1	8	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-182218;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-9636467;Reactome: R-HSA-167590	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Nef Mediated CD8 Down-regulation";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Blockage of phagosome acidification";"Nef Mediated CD4 Down-regulation"
XP_017006619.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_017014301.2	13	MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52	"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation"
XP_017005302.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_017013556.1	8	KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1	"Starch and sucrose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Galactose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_017006937.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044250040.1	5	KEGG: 00020+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33	"Citrate cycle (TCA cycle)";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis"
XP_017013355.2	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_017016086.2	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_017005347.1	3	Reactome: R-HSA-418597;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13	"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_017002606.2	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_017013039.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016994092.2	2	Reactome: R-HSA-390471;Reactome: R-HSA-6791226	"Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017013241.2	4	Reactome: R-HSA-8963888;Reactome: R-HSA-6798695;Reactome: R-HSA-8866423;Reactome: R-HSA-983168	"Chylomicron assembly";"Neutrophil degranulation";"VLDL assembly";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016999690.1	13	Reactome: R-HSA-3928663;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-5627117;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-4420097	"EPHA-mediated growth cone collapse";"Human cytomegalovirus infection";"EPHB-mediated forward signaling";"mTOR signaling pathway";"Sema4D induced cell migration and growth-cone collapse";"RHO GTPases Activate ROCKs";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_044251988.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017015815.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_017006708.2	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_044250167.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_017004985.2	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_016993961.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_044251563.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis"
XP_017006134.2	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_016996368.2	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_017008543.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_017009797.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017006936.2	12	MetaCyc: PWY-5871;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5870;MetaCyc: PWY-5856;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-7233;MetaCyc: PWY-5857;MetaCyc: PWY-7230;MetaCyc: PWY-5873;MetaCyc: PWY-6708;MetaCyc: PWY-5872	"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)"
XP_017012979.2	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_017013587.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_016994895.2	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_016998460.2	56	Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Separation of Sister Chromatids";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017001471.2	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_016996163.1	24	Reactome: R-HSA-202040;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-418597;Reactome: R-HSA-416482;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-418555;Reactome: R-HSA-418217;Reactome: R-HSA-416476;Reactome: R-HSA-163359;Reactome: R-HSA-9009391;Reactome: R-HSA-420092;Reactome: R-HSA-8964616;Reactome: R-HSA-418594;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-4086398;Reactome: R-HSA-6814122;Reactome: R-HSA-432040	"G-protein activation";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"G alpha (z) signalling events";"G alpha (12/13) signalling events";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (s) signalling events";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"Glucagon signaling in metabolic regulation";"Extra-nuclear estrogen signaling";"Glucagon-type ligand receptors";"G beta:gamma signalling through CDC42";"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"Ca2+ pathway";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_017010840.2	7	MetaCyc: PWY-6363;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis"
XP_017008176.2	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_017005343.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_017004610.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016993856.1	25	Reactome: R-HSA-8939256;Reactome: R-HSA-9616222;Reactome: R-HSA-8936459;Reactome: R-HSA-8939242;Reactome: R-HSA-8939247;Reactome: R-HSA-8931987;Reactome: R-HSA-8951911;Reactome: R-HSA-8939245;Reactome: R-HSA-8941333;Reactome: R-HSA-8941858;Reactome: R-HSA-8934593;Reactome: R-HSA-8940973;Reactome: R-HSA-8935964;Reactome: R-HSA-8877330;Reactome: R-HSA-8949275;Reactome: R-HSA-9018519;Reactome: R-HSA-8941284;Reactome: R-HSA-8941326;Reactome: R-HSA-8939236;Reactome: R-HSA-8939246;Reactome: R-HSA-8939243;Reactome: R-HSA-8951936;Reactome: R-HSA-8878166;Reactome: R-HSA-8941332;Reactome: R-HSA-8939902	"RUNX1 regulates transcription of genes involved in WNT signaling";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Regulation of RUNX3 expression and activity";"Regulation of RUNX1 Expression and Activity";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates expression of components of tight junctions";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX3 Regulates Immune Response and Cell Migration";"Estrogen-dependent gene expression";"RUNX2 regulates chondrocyte maturation";"RUNX2 regulates bone development";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX3 regulates p14-ARF";"Transcriptional regulation by RUNX2";"RUNX2 regulates genes involved in cell migration";"Regulation of RUNX2 expression and activity"
XP_017007642.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016994385.2	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_017001804.2	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016993444.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_017015526.2	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_016994691.2	4	Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178;Reactome: R-HSA-3000170	"Integrin cell surface interactions";"Molecules associated with elastic fibres";"ECM proteoglycans";"Syndecan interactions"
XP_017010780.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_017004216.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016993171.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016994866.2	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_017012618.2	13	Reactome: R-HSA-3371511;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5689896;Reactome: R-HSA-382556;Reactome: R-HSA-110320;Reactome: R-HSA-6798695;Reactome: R-HSA-532668;Reactome: R-HSA-5678895;Reactome: R-HSA-8866654;Reactome: R-HSA-8876725;Reactome: R-HSA-9646399;Reactome: R-HSA-5689877	"HSF1 activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Ovarian tumor domain proteases";"ABC-family proteins mediated transport";"Translesion Synthesis by POLH";"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective CFTR causes cystic fibrosis";"E3 ubiquitin ligases ubiquitinate target proteins";"Protein methylation";"Aggrephagy";"Josephin domain DUBs"
XP_017006794.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_017005553.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_044250819.1	7	Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_017004811.2	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_017009541.2	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_017005788.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_017000873.2	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_016998772.2	18	MetaCyc: PWY-6608;MetaCyc: PWY-6611;KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.1;MetaCyc: PWY-5532;MetaCyc: PWY-6627;MetaCyc: PWY-7179-1;Reactome: R-HSA-73621;MetaCyc: PWY-5695;MetaCyc: PWY-4202;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6620;MetaCyc: PWY-7179;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-6644	"Guanosine nucleotides degradation III";"Adenine and adenosine salvage V";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation II";"Pyrimidine catabolism";"Inosine 5'-phosphate degradation";"Arsenate detoxification I (mammalian)";"Purine metabolism";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation I";"Pyrimidine metabolism";"Pyrimidine salvage";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage III";"Fluoroacetate and fluorothreonine biosynthesis"
XP_017013135.1	26	Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-389977;Reactome: R-HSA-68877	"Gap junction assembly";"Kinesins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway";"Mitotic Prometaphase"
XP_016992902.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_017003510.2	4	Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"MHC class II antigen presentation";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044248866.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_017006705.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Translation initiation complex formation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_017012393.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_017000594.2	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_017016204.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_044251744.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_044249486.1	42	Reactome: R-HSA-2559580;Reactome: R-HSA-110329;Reactome: R-HSA-9610379;Reactome: R-HSA-5625886;Reactome: R-HSA-2559586;Reactome: R-HSA-977225;Reactome: R-HSA-1221632;Reactome: R-HSA-5617472;Reactome: R-HSA-3214842;Reactome: R-HSA-1912408;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-201722;Reactome: R-HSA-3214815;Reactome: R-HSA-3214858;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-110328;Reactome: R-HSA-2299718;Reactome: R-HSA-5250924;Reactome: R-HSA-427389;Reactome: R-HSA-912446;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-5693607;Reactome: R-HSA-3214841;Reactome: R-HSA-8939236;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-3214847;Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-171306;Reactome: R-HSA-8936459;Reactome: R-HSA-9616222;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638	"Oxidative Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"HCMV Late Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA Damage/Telomere Stress Induced Senescence";"Amyloid fiber formation";"Meiotic synapsis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HDMs demethylate histones";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex";"HDACs deacetylate histones";"RMTs methylate histone arginines";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Condensation of Prophase Chromosomes";"B-WICH complex positively regulates rRNA expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic recombination";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"Processing of DNA double-strand break ends";"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"DNA methylation";"HATs acetylate histones";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"Packaging Of Telomere Ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation of granulopoiesis";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins"
XP_017011159.2	8	Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324	"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_017001387.2	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007	"Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy"
XP_017009859.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017011612.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_016996724.2	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"Triglyceride catabolism";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_016998113.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016994788.2	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_017012547.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-381676	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_016993847.2	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_017001895.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_017000984.2	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_017014545.2	15	MetaCyc: PWY-7218;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7383;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-5484;KEGG: 00620+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6901;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-8004	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Glycolysis II (from fructose 6-phosphate)";"Pyruvate metabolism";"Purine metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I"
XP_017007255.2	5	Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670	"Neutrophil degranulation";"Sialic acid metabolism";"Glycosphingolipid metabolism";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis"
XP_017016015.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_017014480.2	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_017015813.2	10	Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693607	"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends"
XP_017015985.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_017012401.2	7	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-198323;Reactome: R-HSA-8854214	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"AKT phosphorylates targets in the cytosol";"TBC/RABGAPs"
XP_044251764.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_017000036.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_044249953.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_017001899.2	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_017006406.2	17	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-69473;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-6783310;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938	"mTOR signaling pathway";"Human cytomegalovirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"G2/M DNA damage checkpoint";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Activation of ATR in response to replication stress";"Relaxin signaling pathway";"Thermogenesis";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Fanconi Anemia Pathway";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)"
XP_017010963.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_016998382.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017000294.2	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_017010384.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016998805.2	11	Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1632852;Reactome: R-HSA-5668599;Reactome: R-HSA-1660516;MetaCyc: PWY-6352;Reactome: R-HSA-1660517;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660514;Reactome: R-HSA-168138;Reactome: R-HSA-109704	"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Macroautophagy";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the late endosome membrane";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"Toll Like Receptor 9 (TLR9) Cascade";"PI3K Cascade"
XP_044249759.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_017009443.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090	"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures"
XP_017005611.1	11	MetaCyc: PWY-6596;MetaCyc: PWY-5381;MetaCyc: PWY-6607;MetaCyc: PWY-6608;MetaCyc: PWY-6606;KEGG: 00230+3.1.3.5;KEGG: 00240+3.1.3.5;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7821;MetaCyc: PWY-5695;MetaCyc: PWY-7185	"Adenosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II";"Purine metabolism";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Inosine 5'-phosphate degradation";"UTP and CTP dephosphorylation I"
XP_017007612.2	29	Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-6783310;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5656121;Reactome: R-HSA-5358565;Reactome: R-HSA-3371453;Reactome: R-HSA-69166;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-6804756;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-69473;Reactome: R-HSA-3371511;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-5656169	"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of HSF1-mediated heat shock response";"Removal of the Flap Intermediate";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Regulation of TP53 Activity through Phosphorylation";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"G2/M DNA damage checkpoint";"HSF1 activation";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis"
XP_017007018.2	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_044250797.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_044249656.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016994633.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_016999348.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016996859.2	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_016999657.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044252036.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016999705.2	8	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_044251269.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_017014911.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_017014624.2	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_017013844.2	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_017013291.2	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_016998725.2	3	KEGG: 00600+1.14.19.17;MetaCyc: PWY-5129;Reactome: R-HSA-1660661	"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis"
XP_017014965.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_017004016.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016999649.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_017005929.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017013875.2	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_044250646.1	5	KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_016995516.2	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_017015141.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_017015639.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044252195.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017002953.2	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_017006689.2	4	Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962	"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex"
XP_044249047.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_017014915.2	5	KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22	"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Stachyose degradation";"Sphingolipid metabolism"
XP_044249343.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_017015906.2	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_044249208.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_017010371.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_017010272.2	33	Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-2467813;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-141444;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-159227;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-68877;Reactome: R-HSA-5619107;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-168333	"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Separation of Sister Chromatids";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP independent Mature mRNA";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Mitotic Prometaphase";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"RHO GTPases Activate Formins";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_017004921.2	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_016995531.2	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_044251122.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_017005501.1	12	MetaCyc: PWY-6527;KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7238;MetaCyc: PWY-7343;Reactome: R-HSA-173599;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;Reactome: R-HSA-3322077	"Stachyose degradation";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycerolipid metabolism";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis II";"UDP-alpha-D-glucose biosynthesis I";"Formation of the active cofactor, UDP-glucuronate";"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Glycogen synthesis"
XP_017002330.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016999874.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044248614.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_016997336.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_017015762.2	9	Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape"
XP_044249991.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_017000836.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016994090.2	6	Reactome: R-HSA-70370;MetaCyc: PWY-6317;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;Reactome: R-HSA-5609978;MetaCyc: PWY-6527	"Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Defective GALT can cause Galactosemia";"Stachyose degradation"
XP_044251330.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017013449.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_017000396.2	5	Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5610787	"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'off' state"
XP_017010456.2	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_017016060.2	5	Reactome: R-HSA-68949;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68962	"Orc1 removal from chromatin";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex"
XP_016996979.2	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_017004422.2	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_016996852.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs"
XP_016996203.1	9	MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-6901;Reactome: R-HSA-70171;KEGG: 00710+1.2.1.12;MetaCyc: PWY-1042;Reactome: R-HSA-70263;KEGG: 00010+1.2.1.12	"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis"
XP_017004808.2	2	KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_044252155.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_017003279.2	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_044249811.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017007819.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016997388.2	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_017000736.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_017009010.2	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_044249788.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_016994159.2	12	KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648	"Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"DCC mediated attractive signaling";"Rho GTPase cycle";"mTOR signaling pathway";"Human cytomegalovirus infection";"G alpha (q) signalling events";"Thermogenesis";"Relaxin signaling pathway";"NRAGE signals death through JNK"
XP_017004118.2	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016994275.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_017010691.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017012711.2	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_017005754.2	1	Reactome: R-HSA-70171	"Glycolysis"
XP_017013709.2	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_017010796.1	9	KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7112;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18	"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450";"Glutathione metabolism";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Drug metabolism - other enzymes"
XP_017013704.2	58	MetaCyc: PWY-6583;MetaCyc: PWY-5138;KEGG: 00720+4.2.1.17;MetaCyc: PWY-6944;MetaCyc: PWY-6945;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17;KEGG: 00280+4.2.1.17;MetaCyc: PWY-7401;MetaCyc: PWY-6883;KEGG: 00062+4.2.1.17+1.1.1.211;Reactome: R-HSA-77288;Reactome: R-HSA-77348;MetaCyc: PWY-7654;MetaCyc: PWY-6946;MetaCyc: PWY-1361;KEGG: 00362+4.2.1.17;KEGG: 00281+4.2.1.17;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5177;MetaCyc: PWY-7216;MetaCyc: PWY-5136;KEGG: 00627+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-7656;KEGG: 00410+4.2.1.17;Reactome: R-HSA-77285;Reactome: R-HSA-77350;MetaCyc: PWY-7779;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00650+4.2.1.17;KEGG: 00380+4.2.1.17;MetaCyc: PWY-6435;Reactome: R-HSA-77346;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;Reactome: R-HSA-77310;Reactome: R-HSA-77305;MetaCyc: PWY-5789;Reactome: R-HSA-1482798;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-7726;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-7606;KEGG: 00360+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17;KEGG: 00903+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-7007	"Pyruvate fermentation to butanol I";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Carbon fixation pathways in prokaryotes";"Androstenedione degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Valine, leucine and isoleucine degradation";"Lysine degradation";"Valine, leucine and isoleucine degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid elongation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Benzoyl-coa degradation I (aerobic)";"Benzoate degradation";"Geraniol degradation";"Propanoate metabolism";"Glutaryl-coa degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Aminobenzoate degradation";"Butanoate metabolism";"Fatty acid salvage";"Spodoptera littoralis pheromone biosynthesis";"beta-Alanine metabolism";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Methyl tert-butyl ether degradation";"Carbon fixation pathways in prokaryotes";"Geraniol degradation";"Fatty acid degradation";"Butanoate metabolism";"Tryptophan metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Benzoate degradation";"Tryptophan metabolism";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Acyl chain remodeling of CL";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to hexanol (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Fatty acid elongation";"Fermentation to 2-methylbutanoate";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Phenylalanine metabolism";"Lysine degradation";"Caprolactam degradation";"Limonene and pinene degradation";"Caprolactam degradation";"Toluene degradation";"2-methylpropene degradation";"Methyl ketone biosynthesis (engineered)"
XP_017000479.2	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_017000846.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017000900.2	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_017004615.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_017011724.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_016992800.2	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_044248673.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_017005932.2	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
XP_017005922.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017014451.2	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_017006300.2	3	KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00230+1.7.3.3	"Caffeine metabolism";"Urate conversion to allantoin I";"Purine metabolism"
XP_016994333.1	7	KEGG: 00051+3.1.3.11;KEGG: 00680+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00710+3.1.3.11;KEGG: 00010+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00030+3.1.3.11	"Fructose and mannose metabolism";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Pentose phosphate pathway"
XP_017013970.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_017004417.2	5	Reactome: R-HSA-5620922;Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5610787;Reactome: R-HSA-5635838	"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state";"Activation of SMO"
XP_016998902.2	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_017008327.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017007911.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_017007060.1	5	MetaCyc: PWY-5514;MetaCyc: PWY-6855;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_016999132.2	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_017008872.2	6	KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;MetaCyc: PWY-7426	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_017004084.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016999789.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016992455.1	3	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-948021	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Transport to the Golgi and subsequent modification"
XP_017000320.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044250502.1	3	KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695;MetaCyc: PWY-2161B	"Folate biosynthesis";"Neutrophil degranulation";"Glutamate removal from folates"
XP_016992886.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_017010016.2	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_017005909.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044251162.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017015934.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016994610.2	2	Reactome: R-HSA-1660499;Reactome: R-HSA-1632852	"Synthesis of PIPs at the plasma membrane";"Macroautophagy"
XP_016994635.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_017000098.2	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_017010017.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_017012317.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017014735.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
XP_017011927.2	3	KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317	"Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)"
XP_017004627.1	11	KEGG: 00250+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-6964;MetaCyc: PWY-381;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675;Reactome: R-HSA-210455;KEGG: 00630+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6549;Reactome: R-HSA-8964539	"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Ammonia assimilation cycle II";"Nitrate reduction II (assimilatory)";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glyoxylate and dicarboxylate metabolism";"Arginine biosynthesis";"L-glutamine biosynthesis III";"Glutamate and glutamine metabolism"
XP_017007336.2	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_017007164.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044251520.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_017006872.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016999174.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017011534.2	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_017009191.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_017000463.2	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_017007690.2	33	Reactome: R-HSA-5663220;Reactome: R-HSA-5619107;Reactome: R-HSA-68877;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-2500257;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-141444;Reactome: R-HSA-170822;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-9610379	"RHO GTPases Activate Formins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events"
XP_017012351.2	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_016999505.1	6	Reactome: R-HSA-5099900;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-76005	"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+"
XP_044250171.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_044250288.1	1	Reactome: R-HSA-419771	"Opsins"
XP_017000467.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017004877.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1799339	"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane"
XP_044249446.1	5	Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis"
XP_017005655.2	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_017012544.1	56	Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5607761	"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_044249858.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017004568.2	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_017007674.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017010750.2	5	Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344	"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)"
XP_017002386.2	8	KEGG: 00521+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-6664;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6580;Reactome: R-HSA-1855183;MetaCyc: PWY-6372;MetaCyc: PWY-4661	"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Di-myo-inositol phosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_017004665.2	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_044251712.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016993034.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016993957.2	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016998685.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_017000659.2	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_017000295.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017003315.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016992858.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016996811.2	5	Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_017006446.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044249985.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_017014346.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044248931.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_044248681.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_017009767.1	6	MetaCyc: PWY-6731;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6737;MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-7238	"Starch degradation III";"Starch and sucrose metabolism";"Starch degradation V";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II"
XP_017013832.1	5	Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957	"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_017010009.2	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_017012741.2	20	Reactome: R-HSA-165159;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8943724;Reactome: R-HSA-389357;KEGG: 05170+2.7.11.1;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-1257604;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-3371571;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288	"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Human cytomegalovirus infection";"Regulation of PTEN gene transcription";"CD28 dependent PI3K/Akt signaling";"Human immunodeficiency virus 1 infection";"mTORC1-mediated signalling";"Macroautophagy";"PIP3 activates AKT signaling";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"HSF1-dependent transactivation";"Thermogenesis";"Relaxin signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1"
XP_017005695.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016994695.2	3	Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_016992968.2	3	Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine"
XP_017012860.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017005647.2	8	MetaCyc: PWY-6556;MetaCyc: PWY-7181;MetaCyc: PWY-7193;MetaCyc: PWY-7199;Reactome: R-HSA-6798695;Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5;KEGG: 00240+3.5.4.5	"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides salvage";"Neutrophil degranulation";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_017015663.1	6	MetaCyc: PWY-6854;Reactome: R-HSA-2151201;Reactome: R-HSA-8862803;Reactome: R-HSA-8950505;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017	"Ethylene biosynthesis III (microbes)";"Transcriptional activation of mitochondrial biogenesis";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_016994661.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016999228.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_017010817.2	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_017011726.2	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_017004150.2	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_044251076.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination"
XP_017004500.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016999638.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016996314.2	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_017002897.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_017011984.2	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_017002475.2	4	KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Metabolism of polyamines"
XP_016998959.2	9	MetaCyc: PWY-5744;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-6142	"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_016998400.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017007714.1	4	Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_017002288.2	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_017013571.2	5	MetaCyc: PWY-5189;Reactome: R-HSA-189451;MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37;KEGG: 00860+2.3.1.37	"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism";"Porphyrin and chlorophyll metabolism"
XP_016992405.1	2	KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_016995578.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_017011797.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017015018.2	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_017005210.2	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS I - Hurler syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_017011916.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_044250515.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044248749.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016998866.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_044251428.1	6	MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism"
XP_016999353.2	3	Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-6794361	"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Neurexins and neuroligins"
XP_017004134.2	2	Reactome: R-HSA-5689896;Reactome: R-HSA-5689880	"Ovarian tumor domain proteases";"Ub-specific processing proteases"
XP_016996581.2	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_017013290.2	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_017003493.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044249178.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_017016052.2	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_017012906.2	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826	"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Hypoglycin biosynthesis"
XP_017000302.2	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-5689877	"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"Josephin domain DUBs"
XP_017002091.2	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_016994779.2	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_016995652.2	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_016997148.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044251271.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_017007907.2	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_017007325.2	27	Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-168325	"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis"
XP_044251955.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_017003393.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_017003951.2	5	MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_017011863.2	5	MetaCyc: PWY-7817;MetaCyc: PWY-5667;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41	"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
XP_017016190.2	11	Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-163359	"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Glucagon signaling in metabolic regulation"
XP_016995633.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_017009871.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_017005666.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane"
XP_017011363.2	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_017006549.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_017004487.2	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_017003111.2	12	Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167243	"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery"
XP_017008592.2	5	KEGG: 00900+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560	"Terpenoid backbone biosynthesis";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Methylerythritol phosphate pathway II"
XP_017007963.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_017012633.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016995939.2	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_017000871.2	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_017002610.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044248713.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_017000086.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_016999934.2	7	Reactome: R-HSA-77348;KEGG: 00280+1.3.8.7;KEGG: 00071+1.3.8.7;Reactome: R-HSA-77288;MetaCyc: PWY-7094;Reactome: R-HSA-1989781;Reactome: R-HSA-77346	"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Valine, leucine and isoleucine degradation";"Fatty acid degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Fatty acid salvage";"PPARA activates gene expression";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA"
XP_016999493.2	13	Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-168638;Reactome: R-HSA-2871837;Reactome: R-HSA-975163;Reactome: R-HSA-937042;Reactome: R-HSA-9014325;Reactome: R-HSA-5357956;Reactome: R-HSA-450302;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-937072;Reactome: R-HSA-450321	"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"NOD1/2 Signaling Pathway";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"IRAK2 mediated activation of TAK1 complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"activated TAK1 mediates p38 MAPK activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_044251359.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_017011194.2	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_017000452.2	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_017015146.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118	"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors"
XP_017014872.2	3	Reactome: R-HSA-6804760;Reactome: R-HSA-3214858;Reactome: R-HSA-191859	"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines";"snRNP Assembly"
XP_016999311.2	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_016992903.2	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_016992538.2	13	MetaCyc: PWY-2261;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-7112;MetaCyc: PWY-6370;Reactome: R-HSA-196836;Reactome: R-HSA-156590;KEGG: 00053+1.8.5.1;KEGG: 00983+2.5.1.18	"Ascorbate glutathione cycle";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Ascorbate recycling (cytosolic)";"Vitamin C (ascorbate) metabolism";"Glutathione conjugation";"Ascorbate and aldarate metabolism";"Drug metabolism - other enzymes"
XP_016992994.2	1	Reactome: R-HSA-5676934	"Protein repair"
XP_017007514.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016995873.2	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_016994371.2	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_016998551.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_017004495.2	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_017014143.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017008055.1	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
XP_017013150.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_017012542.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_017010180.1	6	KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-6118;MetaCyc: PWY-6952;MetaCyc: PWY-4261	"Glycerophospholipid metabolism";"Synthesis of PA";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Glycerol degradation I"
XP_017000767.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_017009253.2	7	Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300	"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_016996949.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-2132295	"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation"
XP_017012799.2	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_017015379.2	2	KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399	"Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_017015915.2	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_017000828.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017004030.2	13	MetaCyc: PWY-7184;KEGG: 00480+1.17.4.1;KEGG: 00240+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7227;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7222	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II"
XP_017001645.2	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_017011107.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_017007940.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016999004.2	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_017011132.1	11	KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6549;Reactome: R-HSA-8964539;MetaCyc: PWY-5675;Reactome: R-HSA-210455;MetaCyc: PWY-381;MetaCyc: PWY-6964;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6963	"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"L-glutamine biosynthesis III";"Glutamate and glutamine metabolism";"Nitrate reduction V (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle II";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I"
XP_044250308.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape"
XP_017002884.2	4	MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism"
XP_016999061.2	6	Reactome: R-HSA-418597;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-1250196;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509	"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"SHC1 events in ERBB2 signaling";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling"
XP_017005601.2	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_044250443.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016994660.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_016999636.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016998324.2	56	Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-68949	"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Degradation of AXIN";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin"
XP_017009450.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216	"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization"
XP_016994701.2	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_044251198.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_017006514.2	3	KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662;MetaCyc: PWY-7277	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)"
XP_017005405.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044248930.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_016996399.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017015143.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_017004792.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_044248505.1	5	Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-4641257	"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Protein ubiquitination";"Degradation of AXIN"
XP_017009175.2	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_017009449.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
XP_017016106.2	3	Reactome: R-HSA-480985;Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117	"Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins";"N-Glycan biosynthesis"
XP_016999650.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044248528.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016998553.1	19	Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-3214858;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-8876725;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RMTs methylate histone arginines";"Selenocysteine synthesis";"Translation initiation complex formation";"Viral mRNA Translation";"Peptide chain elongation";"Protein methylation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
XP_017015145.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294	"SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors"
XP_017005324.2	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_044252050.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_016998862.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_017011141.2	12	Reactome: R-HSA-9609736;Reactome: R-HSA-451308;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001	"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"NrCAM interactions";"Synaptic adhesion-like molecules";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade"
XP_017004481.2	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_016997618.2	3	Reactome: R-HSA-162658;Reactome: R-HSA-6807878;Reactome: R-HSA-204005	"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport"
XP_017008867.1	57	Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541	"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway"
XP_017015624.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_017008760.2	10	KEGG: 00710+5.3.1.1;Reactome: R-HSA-70171;KEGG: 00010+5.3.1.1;MetaCyc: PWY-1042;Reactome: R-HSA-70263;MetaCyc: PWY-6142;MetaCyc: PWY-7003;KEGG: 00562+5.3.1.1;MetaCyc: PWY-5484;KEGG: 00051+5.3.1.1	"Carbon fixation in photosynthetic organisms";"Glycolysis";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Inositol phosphate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism"
XP_016999641.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_017014324.2	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_044251296.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_017014073.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017002374.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_016999842.2	5	MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism"
XP_017013019.2	8	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Relaxin signaling pathway";"Thermogenesis"
XP_017013199.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016998921.2	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_016996728.2	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_017001682.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016995909.2	13	Reactome: R-HSA-419037;Reactome: R-HSA-216083;Reactome: R-HSA-1442490;Reactome: R-HSA-3000157;Reactome: R-HSA-2022090;Reactome: R-HSA-1474244;Reactome: R-HSA-186797;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-8948216	"NCAM1 interactions";"Integrin cell surface interactions";"Collagen degradation";"Laminin interactions";"Assembly of collagen fibrils and other multimeric structures";"Extracellular matrix organization";"Signaling by PDGF";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Collagen chain trimerization"
XP_044251195.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016998885.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_017014159.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016999866.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016995029.2	10	Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853	"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"Signal transduction by L1";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes"
XP_044250644.1	5	MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16	"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism"
XP_017013046.2	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016999106.2	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_016998886.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_044250101.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_016992701.2	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_017002731.2	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_017004643.2	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_044251383.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_017005043.2	3	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion"
XP_017001300.1	56	Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5607761	"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_017003533.2	15	Reactome: R-HSA-167152;Reactome: R-HSA-176034;Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-167200;Reactome: R-HSA-2173796;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167287	"Formation of HIV elongation complex in the absence of HIV Tat";"Interactions of Tat with host cellular proteins";"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery"
XP_017010782.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044251013.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016996908.2	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_017015864.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016995734.2	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_016996395.1	7	Reactome: R-HSA-373753;Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878	"Nephrin family interactions";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport"
XP_017013012.2	3	Reactome: R-HSA-446193;Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis"
XP_016996579.1	27	Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408	"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism"
XP_017002287.2	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_017015195.2	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_016999432.1	4	KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage"
XP_017002370.2	7	KEGG: 00230+1.1.1.205;Reactome: R-HSA-73817;MetaCyc: PWY-7221;MetaCyc: PWY-6596;Reactome: R-HSA-6798695;KEGG: 00983+1.1.1.205;MetaCyc: PWY-5695	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine nucleotides degradation I";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Inosine 5'-phosphate degradation"
XP_017014711.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_017007888.2	7	MetaCyc: PWY-6724;MetaCyc: PWY-6737;Reactome: R-HSA-6798695;KEGG: 00500+2.4.1.25;MetaCyc: PWY-7238;Reactome: R-HSA-70221;MetaCyc: PWY-5941	"Starch degradation II";"Starch degradation V";"Neutrophil degranulation";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II"
XP_016993938.2	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_017014695.1	5	Reactome: R-HSA-171007;Reactome: R-HSA-4420097;Reactome: R-HSA-168638;Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24	"p38MAPK events";"VEGFA-VEGFR2 Pathway";"NOD1/2 Signaling Pathway";"DSCAM interactions";"mTOR signaling pathway"
XP_044248808.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_017006063.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_017007482.1	15	MetaCyc: PWY-6142;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-5484;KEGG: 00620+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-7218;MetaCyc: PWY-1042	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Pyruvate metabolism";"Purine metabolism";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)"
XP_017001827.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052	"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state"
XP_044251263.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_017009356.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016999630.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044248820.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_044250155.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_017005249.2	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-1442490	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Collagen degradation"
XP_044249244.1	11	Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-3000170;Reactome: R-HSA-3560783	"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Syndecan interactions";"Defective B4GALT7 causes EDS, progeroid type"
XP_044248936.1	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_017003191.2	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_016996573.2	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_044252052.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_017003314.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_017008090.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044250980.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_016997779.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044250416.1	4	Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by POLK"
XP_017001228.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_017000429.2	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_017007162.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044252013.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_044250839.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016998390.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017015789.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044251613.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_017005479.1	8	Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-983231	"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production"
XP_016998865.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_017004204.1	5	KEGG: 00230+6.3.5.3;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-6121	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_017011008.1	6	Reactome: R-HSA-73817;MetaCyc: PWY-7234;MetaCyc: PWY-6124;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6123;KEGG: 00230+4.1.1.21	"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism"
XP_044251161.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016998920.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044251488.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016994690.2	4	Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170;Reactome: R-HSA-3000178	"Integrin cell surface interactions";"Molecules associated with elastic fibres";"Syndecan interactions";"ECM proteoglycans"
XP_017015545.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Translation initiation complex formation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane"
XP_044251312.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110357	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1"
XP_044250641.1	5	KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_044250281.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_017000896.2	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_017005506.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_017007408.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_017014699.2	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_044250449.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_017002217.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017003361.2	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_017000925.2	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_016999949.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_017006227.2	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_017012917.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017006189.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_017000584.2	17	MetaCyc: PWY-7176;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7227	"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_017009339.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_017011082.1	20	MetaCyc: PWY-7291;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-7007;MetaCyc: PWY-7337;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7340;MetaCyc: PWY-7606;MetaCyc: PWY-7574;MetaCyc: PWY-7858;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-6837;MetaCyc: PWY-7854	"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)"
XP_016997871.2	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_017010968.2	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_017009520.2	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_017014603.1	57	Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-180534	"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Degradation of AXIN";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4"
XP_016997042.2	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_016999002.2	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_044251356.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016998082.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044252227.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017006965.2	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_017003935.2	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_016996985.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_044250585.1	11	Reactome: R-HSA-525793;Reactome: R-HSA-69231;Reactome: R-HSA-8940973;Reactome: R-HSA-428890;Reactome: R-HSA-5685938;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8939236;Reactome: R-HSA-5663213;Reactome: R-HSA-5693565;Reactome: R-HSA-2029482;Reactome: R-HSA-983231	"Myogenesis";"Cyclin D associated events in G1";"RUNX2 regulates osteoblast differentiation";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)";"T cell receptor signaling pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RHO GTPases Activate WASPs and WAVEs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production"
XP_017002818.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016996398.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044251689.1	6	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_017000940.2	4	Reactome: R-HSA-6782861;MetaCyc: PWY-7286;MetaCyc: PWY-7285;MetaCyc: PWY-6829	"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Trna methylation (yeast)"
XP_017002050.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1	"G alpha (i) signalling events";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism"
XP_044251173.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017012982.2	6	Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_016998912.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016996522.2	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_016995294.2	5	MetaCyc: PWY-7919;Reactome: R-HSA-532668;Reactome: R-HSA-4793954;MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106	"Protein N-glycosylation processing phase (plants and animals)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis"
XP_017009831.2	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_016998376.2	9	MetaCyc: PWY-7117;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism"
XP_017015913.2	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_017009867.2	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_017013976.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017011687.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016995987.2	5	Reactome: R-HSA-1169408;Reactome: R-HSA-5668599;Reactome: R-HSA-6804756;Reactome: R-HSA-6811555;Reactome: R-HSA-936440	"ISG15 antiviral mechanism";"RHO GTPases Activate NADPH Oxidases";"Regulation of TP53 Activity through Phosphorylation";"PI5P Regulates TP53 Acetylation";"Negative regulators of DDX58/IFIH1 signaling"
XP_016998538.2	4	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_017006990.2	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_017014329.2	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_017012183.2	9	KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18	"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Drug metabolism - other enzymes"
XP_044250554.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216	"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization"
XP_044250089.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017009820.2	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_016997363.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_017001793.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016999148.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044250452.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_044250079.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_016992844.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017000168.2	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_016997426.2	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_044251581.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_017003401.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_017014734.2	2	Reactome: R-HSA-6811438;Reactome: R-HSA-8873719	"Intra-Golgi traffic";"RAB geranylgeranylation"
XP_017008521.1	15	Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-167158	"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex"
XP_017001942.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044251867.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_017003034.2	6	MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism"
XP_017011150.2	12	Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982	"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Purine metabolism";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_016995405.1	30	Reactome: R-HSA-389513;Reactome: R-HSA-9614399;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804758;Reactome: R-HSA-211163;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-198323;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-198693;Reactome: R-HSA-1358803;Reactome: R-HSA-6804759;Reactome: R-HSA-8941332;Reactome: R-HSA-8876198;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;Reactome: R-HSA-199418;Reactome: R-HSA-69656;Reactome: R-HSA-5218920;KEGG: 05165+2.7.11.1;Reactome: R-HSA-8948751;Reactome: R-HSA-69202;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-9634638;Reactome: R-HSA-392451;Reactome: R-HSA-389357;KEGG: 05170+2.7.11.1	"CTLA4 inhibitory signaling";"Regulation of localization of FOXO transcription factors";"Relaxin signaling pathway";"Regulation of TP53 Activity through Acetylation";"AKT-mediated inactivation of FOXO1A";"Thermogenesis";"Regulation of TP53 Degradation";"AKT phosphorylates targets in the cytosol";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"AKT phosphorylates targets in the nucleus";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of TP53 Activity through Association with Co-factors";"RUNX2 regulates genes involved in cell migration";"RAB GEFs exchange GTP for GDP on RABs";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"Negative regulation of the PI3K/AKT network";"Cyclin A:Cdk2-associated events at S phase entry";"VEGFR2 mediated vascular permeability";"Human papillomavirus infection";"Regulation of PTEN stability and activity";"Cyclin E associated events during G1/S transition";"PI3K-Akt signaling pathway";"PIP3 activates AKT signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"G beta:gamma signalling through PI3Kgamma";"CD28 dependent PI3K/Akt signaling";"Human immunodeficiency virus 1 infection"
XP_016992648.2	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044248672.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016995065.2	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_016992684.1	6	MetaCyc: PWY-6606;MetaCyc: PWY-7442;MetaCyc: PWY-5497;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6608;Reactome: R-HSA-74259	"Guanosine nucleotides degradation II";"Drosopterin and aurodrosopterin biosynthesis";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Guanosine nucleotides degradation III";"Purine catabolism"
XP_016999586.2	3	Reactome: R-HSA-5657562;Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3	"Essential fructosuria";"Fructose catabolism";"Fructose and mannose metabolism"
XP_016992778.2	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_016995111.2	3	Reactome: R-HSA-427389;Reactome: R-HSA-73772;Reactome: R-HSA-8953750	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape";"Transcriptional Regulation by E2F6"
XP_017009789.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017010838.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_017007307.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017008228.1	3	Reactome: R-HSA-727802;Reactome: R-HSA-6787639;Reactome: R-HSA-5619078	"Transport of nucleotide sugars";"GDP-fucose biosynthesis";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)"
XP_017007430.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_017005779.2	8	Reactome: R-HSA-73614;Reactome: R-HSA-6798695;KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7193;MetaCyc: PWY-7181;MetaCyc: PWY-7199;MetaCyc: PWY-6556	"Pyrimidine salvage";"Neutrophil degranulation";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage II"
XP_044252170.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_016999714.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016994693.2	3	Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_044252159.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044249186.1	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2980766;Reactome: R-HSA-2995383	"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation"
XP_016999694.2	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_017011821.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017010297.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_017005531.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Viral mRNA Translation";"Translation initiation complex formation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_016998212.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_017005830.1	26	Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-389977;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-389960;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Gap junction assembly";"Kinesins";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway";"Recycling pathway of L1";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Formation of tubulin folding intermediates by CCT/TriC";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors"
XP_017006303.1	25	Reactome: R-HSA-163359;Reactome: R-HSA-416476;Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-420092;Reactome: R-HSA-381771;Reactome: R-HSA-9009391;Reactome: R-HSA-456926;Reactome: R-HSA-202040;Reactome: R-HSA-428930;Reactome: R-HSA-418555;Reactome: R-HSA-381676;Reactome: R-HSA-418597;Reactome: R-HSA-416482;Reactome: R-HSA-392170;Reactome: R-HSA-432040;Reactome: R-HSA-418592;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-392451;Reactome: R-HSA-4086398;Reactome: R-HSA-500657;Reactome: R-HSA-400042;Reactome: R-HSA-8964315	"Glucagon signaling in metabolic regulation";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"Glucagon-type ligand receptors";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Extra-nuclear estrogen signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"G-protein activation";"Thromboxane signalling through TP receptor";"G alpha (s) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (z) signalling events";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 12";"Vasopressin regulates renal water homeostasis via Aquaporins";"ADP signalling through P2Y purinoceptor 1";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PI3Kgamma";"Ca2+ pathway";"Presynaptic function of Kainate receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK"
XP_017009581.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_017007288.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017007374.2	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_017013521.2	5	Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762	"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation"
XP_044250648.1	5	MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I"
XP_017001831.2	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_016997375.1	30	Reactome: R-HSA-69231;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-2565942;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-400253;Reactome: R-HSA-9604323;Reactome: R-HSA-917937;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-2644607;Reactome: R-HSA-5684264;Reactome: R-HSA-187577;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-1170546;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-983168	"Cyclin D associated events in G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Circadian Clock";"Negative regulation of NOTCH4 signaling";"Iron uptake and transport";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"SCF(Skp2)-mediated degradation of p27/p21";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Prolactin receptor signaling";"Neddylation";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017012504.2	3	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI"
XP_017015905.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016994907.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016998860.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_017015716.2	7	KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;MetaCyc: PWY-2301	"Streptomycin biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Myo-inositol biosynthesis"
XP_016992531.2	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_044252176.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436	"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_017013364.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_017014264.1	13	KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5537;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5913	"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)"
XP_016999848.1	5	KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation"
XP_044248536.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_017007165.1	18	MetaCyc: PWY-6803;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-7409;MetaCyc: PWY-8051;Reactome: R-HSA-1482788	"Phosphatidylcholine acyl editing";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PC"
XP_017013971.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_017001396.2	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_044248606.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_017000901.2	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016995882.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_016995705.2	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_017005595.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_017010238.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_017000805.2	1	Reactome: R-HSA-6782861	"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_017001071.2	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_017006682.2	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_017004010.2	31	MetaCyc: PWY-7723;Reactome: R-HSA-2426168;MetaCyc: PWY-7663;MetaCyc: PWY-8047;MetaCyc: PWY-5989;Reactome: R-HSA-163765;MetaCyc: PWYG-321;Reactome: R-HSA-199220;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5971;MetaCyc: PWY-6282;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;MetaCyc: PWY-5367;MetaCyc: PWY-8012;MetaCyc: PWY-7858;MetaCyc: PWY-7664;MetaCyc: PWY-5966-1;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;MetaCyc: PWY-4381;MetaCyc: PWY-5973;MetaCyc: PWY-7388;MetaCyc: PWY-6519;MetaCyc: PWY-7746;MetaCyc: PWY-5142;MetaCyc: PWY-8049;MetaCyc: PWY-5994;MetaCyc: PWY-5147;MetaCyc: PWY-6799;MetaCyc: PWY-5366	"Bacterial bioluminescence";"Activation of gene expression by SREBF (SREBP)";"Gondoate biosynthesis (anaerobic)";"Bryostatin biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"ChREBP activates metabolic gene expression";"";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"Petroselinate biosynthesis";"Mupirocin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Cis-vaccenate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"8-amino-7-oxononanoate biosynthesis I";"Mycobacterial sulfolipid biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Pederin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitoleate biosynthesis II (plants and bacteria)"
XP_017010756.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-204174;Reactome: R-HSA-8963684	"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism"
XP_016997096.2	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_016997260.2	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_017002875.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_017004408.2	3	MetaCyc: PWY-7511;Reactome: R-HSA-6807505;Reactome: R-HSA-983168	"Protein ubiquitination";"RNA polymerase II transcribes snRNA genes";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044249108.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_017000344.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_017009179.2	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_017014118.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_017002933.2	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_016998724.2	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_017000435.2	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_016997769.2	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_016993234.2	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_017005149.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_017008584.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016996477.1	4	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events"
XP_017005765.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_017004201.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017013723.2	6	MetaCyc: PWY-6368;MetaCyc: PWY-6367;Reactome: R-HSA-1660499;MetaCyc: PWY-6580;KEGG: 04070+3.1.3.64+3.1.3.95;KEGG: 00562+3.1.3.64+3.1.3.95	"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol biosynthesis I (bacteria)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_017001841.2	4	Reactome: R-HSA-4755583;MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108;Reactome: R-HSA-446199	"Defective DOLK causes DOLK-CDG (CDG-1m)";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_017003101.2	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_016995229.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017005468.2	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_017009869.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_016998244.1	9	Reactome: R-HSA-2871809;Reactome: R-HSA-4420097;Reactome: R-HSA-114604;Reactome: R-HSA-5218920;Reactome: R-HSA-416482;Reactome: R-HSA-2871796;Reactome: R-HSA-2029482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"FCERI mediated Ca+2 mobilization";"VEGFA-VEGFR2 Pathway";"GPVI-mediated activation cascade";"VEGFR2 mediated vascular permeability";"G alpha (12/13) signalling events";"FCERI mediated MAPK activation";"Regulation of actin dynamics for phagocytic cup formation";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_017002575.2	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_017013583.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_017010183.2	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_017013456.2	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_017003001.2	5	Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_044252147.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_017012657.2	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_044248595.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016993690.2	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_044248618.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_017011952.2	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_017002332.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_017000448.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_017002351.2	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044249332.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_017015698.2	9	MetaCyc: PWY-7852;MetaCyc: PWY-5664;MetaCyc: PWY-6147;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-6983;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16	"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Preq0 biosynthesis";"Folate biosynthesis"
XP_016996819.2	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_017001456.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_017006796.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016998067.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_017015127.1	2	Reactome: R-HSA-191859;Reactome: R-HSA-6807505	"snRNP Assembly";"RNA polymerase II transcribes snRNA genes"
XP_016996335.2	5	Reactome: R-HSA-73621;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3	"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes"
XP_017015859.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_016996585.2	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_017016079.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_017012910.2	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-8001	"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_017010964.2	4	MetaCyc: PWY-7920;KEGG: 00510+3.2.1.114;MetaCyc: PWY-7426;KEGG: 00513+3.2.1.114	"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis"
XP_017006236.2	4	KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051	"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I"
XP_044250064.1	9	MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-6142;Reactome: R-HSA-1475029	"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide"
XP_044250501.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_017002762.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_017007071.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044249539.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_017015741.2	5	Reactome: R-HSA-380994;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4	"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_017003955.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_017015931.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016993654.2	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_017008798.2	33	Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-2467813;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-141444;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-5619107;Reactome: R-HSA-68877;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-191859	"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Separation of Sister Chromatids";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"RHO GTPases Activate Formins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"snRNP Assembly"
XP_017002361.1	7	Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-180746;Reactome: R-HSA-203927	"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein";"MicroRNA (miRNA) biogenesis"
XP_017004067.1	182	Reactome: R-HSA-72649;Reactome: R-HSA-75815;Reactome: R-HSA-1253288;Reactome: R-HSA-3785653;Reactome: R-HSA-5656169;Reactome: R-HSA-1799339;Reactome: R-HSA-68949;Reactome: R-HSA-5357905;Reactome: R-HSA-9010553;Reactome: R-HSA-2672351;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-5684264;Reactome: R-HSA-8939236;Reactome: R-HSA-2122947;Reactome: R-HSA-937039;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-168638;Reactome: R-HSA-209543;Reactome: R-HSA-983168;Reactome: R-HSA-174490;Reactome: R-HSA-1169091;Reactome: R-HSA-2173795;Reactome: R-HSA-937041;Reactome: R-HSA-110314;Reactome: R-HSA-8948747;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-174048;Reactome: R-HSA-912631;Reactome: R-HSA-69541;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1295596;Reactome: R-HSA-8939902;Reactome: R-HSA-975956;Reactome: R-HSA-182971;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-8856825;Reactome: R-HSA-5654726;Reactome: R-HSA-4641258;Reactome: R-HSA-450321;Reactome: R-HSA-5689603;Reactome: R-HSA-2691232;Reactome: R-HSA-2565942;Reactome: R-HSA-5689880;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-8866654;Reactome: R-HSA-3322077;Reactome: R-HSA-9615710;Reactome: R-HSA-5696394;Reactome: R-HSA-5676590;Reactome: R-HSA-2122948;Reactome: R-HSA-5696395;Reactome: R-HSA-5610783;Reactome: R-HSA-6781823;Reactome: R-HSA-450408;Reactome: R-HSA-9636383;Reactome: R-HSA-937042;Reactome: R-HSA-8849469;Reactome: R-HSA-8866652;Reactome: R-HSA-8951664;Reactome: R-HSA-175474;Reactome: R-HSA-975144;Reactome: R-HSA-5205685;Reactome: R-HSA-201681;Reactome: R-HSA-2173788;Reactome: R-HSA-5675221;Reactome: R-HSA-975110;Reactome: R-HSA-5689901;Reactome: R-HSA-9014325;Reactome: R-HSA-901032;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-72764;Reactome: R-HSA-382556;Reactome: R-HSA-5685942;Reactome: R-HSA-917729;Reactome: R-HSA-2871837;Reactome: R-HSA-110312;Reactome: R-HSA-4641257;Reactome: R-HSA-2979096;Reactome: R-HSA-5654727;Reactome: R-HSA-6782135;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-156902;Reactome: R-HSA-168928;Reactome: R-HSA-3134975;Reactome: R-HSA-450302;Reactome: R-HSA-5357956;Reactome: R-HSA-174154;Reactome: R-HSA-2173796;Reactome: R-HSA-9013507;Reactome: R-HSA-1234176;Reactome: R-HSA-5696400;Reactome: R-HSA-9613829;Reactome: R-HSA-1358803;Reactome: R-HSA-5693607;Reactome: R-HSA-5610785;Reactome: R-HSA-5689877;Reactome: R-HSA-205043;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-2408557;Reactome: R-HSA-69231;Reactome: R-HSA-975163;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-400253;Reactome: R-HSA-6782210;Reactome: R-HSA-5693565;Reactome: R-HSA-9637628;Reactome: R-HSA-5654733;Reactome: R-HSA-977225;Reactome: R-HSA-2559585;Reactome: R-HSA-445989;Reactome: R-HSA-8875360;Reactome: R-HSA-5607761;Reactome: R-HSA-9633012;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-162588;Reactome: R-HSA-5656121;Reactome: R-HSA-179409;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-110320;Reactome: R-HSA-3769402;Reactome: R-HSA-69601;Reactome: R-HSA-936440;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-532668;Reactome: R-HSA-2559582;Reactome: R-HSA-5654732;Reactome: R-HSA-8863795;Reactome: R-HSA-5675482;Reactome: R-HSA-168927;Reactome: R-HSA-349425;Reactome: R-HSA-1169408;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-937072;Reactome: R-HSA-72695;Reactome: R-HSA-6783310;Reactome: R-HSA-6804760;Reactome: R-HSA-192823;Reactome: R-HSA-8856828;Reactome: R-HSA-5689896;Reactome: R-HSA-211733;Reactome: R-HSA-2173791;Reactome: R-HSA-209560;Reactome: R-HSA-9013973;Reactome: R-HSA-9033241;Reactome: R-HSA-9646399;Reactome: R-HSA-917937;Reactome: R-HSA-72689;Reactome: R-HSA-187577;Reactome: R-HSA-72706;Reactome: R-HSA-9645460;Reactome: R-HSA-5655862;Reactome: R-HSA-2559580;Reactome: R-HSA-202424;Reactome: R-HSA-936964;Reactome: R-HSA-1236382;Reactome: R-HSA-6807004;Reactome: R-HSA-2467813;Reactome: R-HSA-8876493;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-4641263	"Translation initiation complex formation";"Ubiquitin-dependent degradation of Cyclin D";"Downregulation of ERBB4 signaling";"Myoclonic epilepsy of Lafora";"Termination of translesion DNA synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Orc1 removal from chromatin";"Regulation of TNFR1 signaling";"Regulation of expression of SLITs and ROBOs";"Stimuli-sensing channels";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NOTCH1 Intracellular Domain Regulates Transcription";"IRAK1 recruits IKK complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"NOD1/2 Signaling Pathway";"p75NTR recruits signalling complexes";"Antigen processing: Ubiquitination & Proteasome degradation";"Membrane binding and targetting of GAG proteins";"Activation of NF-kappaB in B cells";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"IKK complex recruitment mediated by RIP1";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of PTEN localization";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of signaling by CBL";"Stabilization of p53";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Spry regulation of FGF signaling";"Regulation of RUNX2 expression and activity";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"EGFR downregulation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of FGFR1 signaling";"Degradation of DVL";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"UCH proteinases";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"Ub-specific processing proteases";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"E3 ubiquitin ligases ubiquitinate target proteins";"Glycogen synthesis";"Late endosomal microautophagy";"DNA Damage Recognition in GG-NER";"NIK-->noncanonical NF-kB signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Formation of Incision Complex in GG-NER";"Degradation of GLI2 by the proteasome";"Formation of TC-NER Pre-Incision Complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Prevention of phagosomal-lysosomal fusion";"IRAK2 mediated activation of TAK1 complex";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Neddylation";"Assembly Of The HIV Virion";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Pink/Parkin Mediated Mitophagy";"TCF dependent signaling in response to WNT";"Downregulation of TGF-beta receptor signaling";"Negative regulation of MAPK pathway";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Metalloprotease DUBs";"TICAM1,TRAF6-dependent induction of TAK1 complex";"ER Quality Control Compartment (ERQC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Eukaryotic Translation Termination";"ABC-family proteins mediated transport";"HDR through Homologous Recombination (HRR)";"Endosomal Sorting Complex Required For Transport (ESCRT)";"FCERI mediated NF-kB activation";"Translesion synthesis by REV1";"Degradation of AXIN";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Negative regulation of FGFR2 signaling";"Dual incision in TC-NER";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Peptide chain elongation";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Regulation of innate immune responses to cytosolic DNA";"activated TAK1 mediates p38 MAPK activation";"TNFR1-induced NFkappaB signaling pathway";"APC/C:Cdc20 mediated degradation of Securin";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dual Incision in GG-NER";"Chaperone Mediated Autophagy";"Downregulation of ERBB2:ERBB3 signaling";"Processing of DNA double-strand break ends";"GLI3 is processed to GLI3R by the proteasome";"Josephin domain DUBs";"NRIF signals cell death from the nucleus";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Selenocysteine synthesis";"Cyclin D associated events in G1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Circadian Clock";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Modulation by Mtb of host immune system";"Negative regulation of FGFR4 signaling";"Amyloid fiber formation";"Oncogene Induced Senescence";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"InlB-mediated entry of Listeria monocytogenes into host cell";"Dectin-1 mediated noncanonical NF-kB signaling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Budding and maturation of HIV virion";"Translesion synthesis by POLI";"APC-Cdc20 mediated degradation of Nek2A";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Translesion Synthesis by POLH";"Deactivation of the beta-catenin transactivating complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Negative regulators of DDX58/IFIH1 signaling";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Senescence-Associated Secretory Phenotype (SASP)";"Negative regulation of FGFR3 signaling";"Downregulation of ERBB2 signaling";"Regulation of necroptotic cell death";"TICAM1, RIP1-mediated IKK complex recruitment";"Autodegradation of the E3 ubiquitin ligase COP1";"ISG15 antiviral mechanism";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Formation of the ternary complex, and subsequently, the 43S complex";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Methylation";"Viral mRNA Translation";"Clathrin-mediated endocytosis";"Ovarian tumor domain proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"NF-kB is activated and signals survival";"TICAM1-dependent activation of IRF3/IRF7";"Peroxisomal protein import";"Aggrephagy";"Iron uptake and transport";"Formation of a pool of free 40S subunits";"SCF(Skp2)-mediated degradation of p27/p21";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Alpha-protein kinase 1 signaling pathway";"Translesion synthesis by POLK";"Oxidative Stress Induced Senescence";"Downstream TCR signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Negative regulation of MET activity";"Separation of Sister Chromatids";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of FZD by ubiquitination"
XP_016994736.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044250168.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_017014867.2	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_017007523.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_017005093.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_016999727.2	56	Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858	"Separation of Sister Chromatids";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity"
XP_017010333.2	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_017007476.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_017013688.2	19	Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-8964038;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-8856828;Reactome: R-HSA-432142;Reactome: R-HSA-3000484;Reactome: R-HSA-8964026;Reactome: R-HSA-3000497;Reactome: R-HSA-8856825;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-8963888;Reactome: R-HSA-381426	"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"VLDL clearance";"Scavenging by Class B Receptors";"Chylomicron remodeling";"LDL clearance";"LDL remodeling";"Regulation of TLR by endogenous ligand";"Clathrin-mediated endocytosis";"Platelet sensitization by LDL";"Scavenging by Class F Receptors";"Chylomicron clearance";"Scavenging by Class H Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"VLDL assembly";"Chylomicron assembly";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_016996490.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_017007748.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_017001388.2	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007	"Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy"
XP_016998876.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_017007794.2	4	MetaCyc: PWY-7174;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_017001507.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_017012159.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975957	"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_017002098.2	18	MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482839;MetaCyc: PWY-8051;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4	"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PE";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Arachidonic acid metabolism";"Glycerophospholipid metabolism"
XP_044250851.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_017015749.2	3	KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695	"Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation"
XP_017014108.2	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_017008926.2	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_044249256.1	10	Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-2197563;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408	"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation"
XP_017012047.2	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_017012464.2	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_016998856.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_044249822.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044251289.1	4	Reactome: R-HSA-912631;Reactome: R-HSA-8875656;Reactome: R-HSA-8875555;Reactome: R-HSA-186763	"Regulation of signaling by CBL";"MET receptor recycling";"MET activates RAP1 and RAC1";"Downstream signal transduction"
XP_017014437.2	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_017015080.2	5	KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;MetaCyc: PWY-5381;Reactome: R-HSA-1368108	"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_017013352.2	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_016999013.2	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_016996289.1	19	Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-9617324	"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Long-term potentiation";"RAF activation";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_016993235.2	4	KEGG: 00860+2.5.1.61;MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis"
XP_016996636.2	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_017014345.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017008352.2	11	KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00565+3.1.3.4;Reactome: R-HSA-2029485;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-7782	"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis"
XP_017005737.2	13	MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-7384;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00620+4.2.1.2;MetaCyc: PWY-561;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.2;MetaCyc: PWY-8086	"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_017000006.2	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_044248684.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_017005486.2	5	Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-380994	"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_017007461.1	7	MetaCyc: PWY-7221;Reactome: R-HSA-212676;Reactome: R-HSA-9609736;Reactome: R-HSA-373753;KEGG: 00230+2.7.4.8;Reactome: R-HSA-6794361;Reactome: R-HSA-3000170	"Guanosine ribonucleotides de novo biosynthesis";"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors";"Nephrin family interactions";"Purine metabolism";"Neurexins and neuroligins";"Syndecan interactions"
XP_044250576.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016993042.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_017009114.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_017012771.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_044251737.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_016994196.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017007463.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_017002615.2	5	MetaCyc: PWY-5667;MetaCyc: PWY-7817;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41	"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
XP_017003024.2	17	KEGG: 00240+2.4.2.1;Reactome: R-HSA-6798695;Reactome: R-HSA-74259;MetaCyc: PWY-5532;MetaCyc: PWY-6611;MetaCyc: PWY-6608;MetaCyc: PWY-5695;MetaCyc: PWY-4202;MetaCyc: PWY-6627;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;MetaCyc: PWY-6620;KEGG: 00230+2.4.2.1;Reactome: R-HSA-74217;MetaCyc: PWY-6644;MetaCyc: PWY-6609;KEGG: 00760+2.4.2.1	"Pyrimidine metabolism";"Neutrophil degranulation";"Purine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage V";"Guanosine nucleotides degradation III";"Inosine 5'-phosphate degradation";"Arsenate detoxification I (mammalian)";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Guanine and guanosine salvage";"Purine metabolism";"Purine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Adenine and adenosine salvage III";"Nicotinate and nicotinamide metabolism"
XP_016998770.2	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_017011206.2	5	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_016997879.2	9	Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome"
XP_017010624.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-202040	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"PLC beta mediated events";"G-protein activation"
XP_017012476.2	7	Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_017013582.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_044251116.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_017005545.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_017000373.2	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_017013477.2	17	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-174154	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin"
XP_017002088.2	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016996667.2	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_016995945.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_017008775.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017013863.2	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_017009853.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044252171.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295	"Aggrephagy";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"MHC class II antigen presentation"
XP_016993300.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_017003102.2	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_016998609.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_044250481.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_016995044.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016999637.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044251331.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017011138.2	12	Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8	"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Synaptic adhesion-like molecules";"Purine metabolism"
XP_017002421.2	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_044249778.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017011380.1	12	KEGG: 00030+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1042;Reactome: R-HSA-70263;MetaCyc: PWY-7385;MetaCyc: PWY-1861;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00010+4.1.2.13	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Glycolysis";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis"
XP_044251051.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044250982.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_017001840.2	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_017013152.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016994069.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_044250519.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016992989.2	33	MetaCyc: PWY-3162;MetaCyc: PWY-7396;Reactome: R-HSA-71384;MetaCyc: PWY-5076;MetaCyc: PWY-6802;MetaCyc: PWY-6333;MetaCyc: PWY-7013;KEGG: 00260+1.1.1.1;MetaCyc: PWY-6587;KEGG: 00592+1.1.1.1;MetaCyc: PWY-5057;KEGG: 00982+1.1.1.1;MetaCyc: PWY-7798;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5082;MetaCyc: PWY-1801;MetaCyc: PWY-6313;KEGG: 00071+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5480;MetaCyc: PWY-5079;MetaCyc: PWY-6342;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5751;MetaCyc: PWY-6871;KEGG: 00010+1.1.1.1;KEGG: 00625+1.1.1.1;KEGG: 00680+1.1.1.284;KEGG: 00830+1.1.1.1;MetaCyc: PWY-7111;MetaCyc: PWY-5078;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5486	"L-tryptophan degradation V (side chain pathway)";"Butanol and isobutanol biosynthesis (engineered)";"Ethanol oxidation";"L-leucine degradation III";"Salidroside biosynthesis";"Acetaldehyde biosynthesis I";"(S)-propane-1,2-diol degradation";"Glycine, serine and threonine metabolism";"Pyruvate fermentation to ethanol III";"alpha-Linolenic acid metabolism";"L-valine degradation II";"Drug metabolism - cytochrome P450";"Protein S-nitrosylation and denitrosylation";"Metabolism of xenobiotics by cytochrome P450";"L-methionine degradation III";"Formaldehyde oxidation II (glutathione-dependent)";"Serotonin degradation";"Fatty acid degradation";"Chitin degradation to ethanol";"Pyruvate fermentation to ethanol I";"L-phenylalanine degradation III";"Noradrenaline and adrenaline degradation";"Tyrosine metabolism";"Phenylethanol biosynthesis";"3-methylbutanol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Chloroalkane and chloroalkene degradation";"Methane metabolism";"Retinol metabolism";"Pyruvate fermentation to isobutanol (engineered)";"L-isoleucine degradation II";"Naphthalene degradation";"Pyruvate fermentation to ethanol II"
XP_017010293.2	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_017012314.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017005062.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_017000965.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_017011887.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016992856.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_017015363.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016998873.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_017014866.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016999734.2	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_044249730.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_044251577.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_017014508.2	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_016995225.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017013141.2	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_017003386.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017001015.2	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_017008401.2	6	Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-456926	"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_017004289.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"Triglyceride catabolism";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_017001653.2	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_017009438.2	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_017006198.2	15	Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-111465;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-5467333;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-5467337;Reactome: R-HSA-5689896	"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases"
XP_044252032.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044249404.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_017001872.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660661	"Neutrophil degranulation";"Sphingolipid de novo biosynthesis"
XP_017014139.2	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_017009964.2	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_017012908.2	10	MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2	"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism"
XP_017012565.2	5	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-1655829	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_017000617.2	3	MetaCyc: PWY-8099;MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96	"Tetrahydropteridine recycling";"L-phenylalanine degradation V";"Folate biosynthesis"
XP_016995447.2	4	KEGG: 00280+1.2.1.27;Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism";"2,4-dinitrotoluene degradation"
XP_017007241.2	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_017014496.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_017014969.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_016999728.1	57	Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Separation of Sister Chromatids";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway"
XP_017005715.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_017015134.2	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_044251118.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044249556.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_017014966.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_016997820.2	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044250836.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_044251676.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_017002382.2	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_017000239.1	10	MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00030+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;KEGG: 00010+2.7.1.11	"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Glycolysis";"Methane metabolism";"Glycolysis / Gluconeogenesis"
XP_017005513.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016993344.2	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_017007401.2	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_017007058.1	5	MetaCyc: PWY-5514;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6906	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin derivatives degradation"
XP_017011148.2	8	Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_017011134.2	12	MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982	"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_017010239.2	14	Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-8948700	"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_044249419.1	42	Reactome: R-HSA-5693571;Reactome: R-HSA-201722;Reactome: R-HSA-3214815;Reactome: R-HSA-3214858;Reactome: R-HSA-69473;Reactome: R-HSA-2299718;Reactome: R-HSA-5250924;Reactome: R-HSA-5693565;Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-110329;Reactome: R-HSA-9610379;Reactome: R-HSA-5625886;Reactome: R-HSA-977225;Reactome: R-HSA-2559586;Reactome: R-HSA-1221632;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-3214842;Reactome: R-HSA-1912408;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-9616222;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-171306;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-8939236;Reactome: R-HSA-73772;Reactome: R-HSA-912446;Reactome: R-HSA-427389;Reactome: R-HSA-73728;Reactome: R-HSA-5693607;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749	"Nonhomologous End-Joining (NHEJ)";"Formation of the beta-catenin:TCF transactivating complex";"HDACs deacetylate histones";"RMTs methylate histone arginines";"G2/M DNA damage checkpoint";"Condensation of Prophase Chromosomes";"B-WICH complex positively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Cleavage of the damaged pyrimidine";"HCMV Late Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Amyloid fiber formation";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic synapsis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDMs demethylate histones";"Pre-NOTCH Transcription and Translation";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"PRC2 methylates histones and DNA";"Transcriptional regulation of granulopoiesis";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Packaging Of Telomere Ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Promoter Escape";"Meiotic recombination";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Opening";"Processing of DNA double-strand break ends";"Estrogen-dependent gene expression";"DNA methylation";"HATs acetylate histones";"Transcriptional regulation by small RNAs"
XP_017008989.2	1	Reactome: R-HSA-419771	"Opsins"
XP_016993089.2	5	Reactome: R-HSA-111458;MetaCyc: PWY-4361;KEGG: 00270+4.2.1.109;Reactome: R-HSA-9627069;Reactome: R-HSA-1237112	"Formation of apoptosome";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Regulation of the apoptosome activity";"Methionine salvage pathway"
XP_016994914.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_017011717.2	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_017005844.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_044250176.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_017012798.1	6	Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957	"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_017005465.2	5	Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-196108;Reactome: R-HSA-5579026	"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_044251740.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_017000904.1	5	Reactome: R-HSA-162710;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377;Reactome: R-HSA-4719360;Reactome: R-HSA-162699	"Synthesis of glycosylphosphatidylinositol (GPI)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of dolichyl-phosphate mannose"
XP_016993377.2	18	Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-7409;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;MetaCyc: PWY-7416	"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_016997229.2	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_044250074.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_017004732.2	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_017005918.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016996941.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"MHC class II antigen presentation"
XP_044251518.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_017013864.2	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_017007473.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_017014350.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016997154.1	7	KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.22	"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Glutathione metabolism"
XP_017002209.1	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
XP_017007397.2	6	KEGG: 00260+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-5484;MetaCyc: PWY-8004;KEGG: 00680+5.4.2.11	"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Methane metabolism"
XP_017007505.2	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_017014741.2	3	Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_016998537.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016995930.1	8	KEGG: 00520+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-5738;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5740;MetaCyc: PWY-5739;MetaCyc: PWY-66;MetaCyc: PWY-7573	"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"Fructose and mannose metabolism";"GDP-L-colitose biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-mycosamine biosynthesis"
XP_017015191.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_017015231.2	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_016993721.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_016995068.2	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_016992471.2	3	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_044251444.1	9	MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-6142;Reactome: R-HSA-1475029	"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide"
XP_016999798.2	4	Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14	"Pyrimidine catabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism"
XP_017000374.2	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_017013383.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044251833.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016999122.2	57	Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_016993083.2	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_017011894.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017001148.2	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_017005239.2	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_017011862.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017006207.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016996148.2	6	Reactome: R-HSA-2426168;Reactome: R-HSA-446199;Reactome: R-HSA-191273;MetaCyc: PWY-7391;KEGG: 00900+4.1.1.33;MetaCyc: PWY-922	"Activation of gene expression by SREBF (SREBP)";"Synthesis of Dolichyl-phosphate";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I"
XP_017003105.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016994208.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017010923.2	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975957	"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_016996333.2	5	Reactome: R-HSA-73614;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621	"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine catabolism"
XP_044249762.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_044252172.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_017013568.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016998605.2	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_017001468.2	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_017005027.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_016996416.1	12	Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167243	"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery"
XP_017008301.2	4	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation"
XP_017000394.2	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_016996646.2	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_017009658.2	3	Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-5696394	"UCH proteinases";"HATs acetylate histones";"DNA Damage Recognition in GG-NER"
XP_017014352.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017010199.2	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_017014494.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_017011708.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_044251111.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016996593.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_017000977.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_044252062.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_017001871.1	3	MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism"
XP_016996944.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399	"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Aggrephagy"
XP_016996164.1	24	Reactome: R-HSA-418594;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-500657;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-432040;Reactome: R-HSA-456926;Reactome: R-HSA-202040;Reactome: R-HSA-418597;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-392170;Reactome: R-HSA-163359;Reactome: R-HSA-418217;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-9009391;Reactome: R-HSA-420092	"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thrombin signalling through proteinase activated receptors (PARs)";"G-protein activation";"G alpha (z) signalling events";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 12";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"Extra-nuclear estrogen signaling";"Glucagon-type ligand receptors"
XP_017001875.2	6	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling"
XP_017000704.2	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)"
XP_016997730.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_044250811.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016996488.2	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_017015724.1	4	Reactome: R-HSA-156581;Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-6782315	"Methylation";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"tRNA modification in the nucleus and cytosol"
XP_017001607.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_017012650.2	5	Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695	"Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation"
XP_016996146.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017013607.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane"
XP_017015284.2	24	Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-68877	"Gap junction assembly";"Kinesins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"HCMV Early Events";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase"
XP_017011143.2	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_044249056.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_017009756.1	16	MetaCyc: PWY-7218;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-1622;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-7124;MetaCyc: PWY-1042;KEGG: 00680+4.2.1.11;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-6142;MetaCyc: PWY-7003;KEGG: 00010+4.2.1.11	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis"
XP_017002985.2	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_017001608.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016992953.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017007733.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016993968.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016995500.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_017011415.2	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS II - Hunter syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_016999098.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_017004007.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016998900.2	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_017010012.2	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_044249731.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_017008139.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044249689.1	5	KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation"
XP_017003316.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_017007780.2	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_017015236.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_017001123.2	10	MetaCyc: PWY-6352;KEGG: 04070+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 05163+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05165+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 05170+2.7.1.153;KEGG: 00562+2.7.1.153	"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human papillomavirus infection";"Synthesis of PIPs at the plasma membrane";"Human immunodeficiency virus 1 infection";"Inositol phosphate metabolism"
XP_017012321.2	14	KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7409;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803	"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing"
XP_044251197.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_017001253.1	52	Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-5250924;Reactome: R-HSA-76042;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-76071;Reactome: R-HSA-168325;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-76066;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-167238;Reactome: R-HSA-73863;Reactome: R-HSA-167243;Reactome: R-HSA-6803529;Reactome: R-HSA-77075;Reactome: R-HSA-5617472;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-73762;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-167162;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-72086;Reactome: R-HSA-1834949;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-5578749;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-749476;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-72165;Reactome: R-HSA-73772;Reactome: R-HSA-5601884	"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Viral Messenger RNA Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Transcription Termination";"Tat-mediated HIV elongation arrest and recovery";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"mRNA Capping";"Cytosolic sensors of pathogen-associated DNA";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"Transcriptional regulation by small RNAs";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Minor Pathway";"RNA Polymerase I Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis"
XP_017013599.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_016996959.2	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_017014879.1	9	Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-166208;Reactome: R-HSA-380972	"Regulation of PTEN gene transcription";"mTOR signalling";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Neutrophil degranulation";"MAP2K and MAPK activation";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_016994634.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016999088.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_016994059.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_044250122.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_017013100.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_017008828.2	4	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-418594	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"G alpha (i) signalling events"
XP_017014910.2	9	Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-69205	"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription"
XP_017007293.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_017004556.2	5	Reactome: R-HSA-211981;Reactome: R-HSA-8937144;Reactome: R-HSA-1989781;Reactome: R-HSA-211976;Reactome: R-HSA-211945	"Xenobiotics";"Aryl hydrocarbon receptor signalling";"PPARA activates gene expression";"Endogenous sterols";"Phase I - Functionalization of compounds"
XP_017006304.1	25	Reactome: R-HSA-432040;Reactome: R-HSA-6814122;Reactome: R-HSA-500657;Reactome: R-HSA-4086398;Reactome: R-HSA-392451;Reactome: R-HSA-8964315;Reactome: R-HSA-400042;Reactome: R-HSA-418594;Reactome: R-HSA-418592;Reactome: R-HSA-392851;Reactome: R-HSA-8964616;Reactome: R-HSA-9009391;Reactome: R-HSA-381771;Reactome: R-HSA-420092;Reactome: R-HSA-163359;Reactome: R-HSA-418217;Reactome: R-HSA-416476;Reactome: R-HSA-418597;Reactome: R-HSA-416482;Reactome: R-HSA-381676;Reactome: R-HSA-418555;Reactome: R-HSA-428930;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-202040	"Vasopressin regulates renal water homeostasis via Aquaporins";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Presynaptic function of Kainate receptors";"Ca2+ pathway";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through BTK";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 1";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through CDC42";"Extra-nuclear estrogen signaling";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Glucagon-type ligand receptors";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"G alpha (z) signalling events";"G alpha (12/13) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (s) signalling events";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"G-protein activation"
XP_016995231.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016996162.1	24	Reactome: R-HSA-420092;Reactome: R-HSA-9009391;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-418217;Reactome: R-HSA-163359;Reactome: R-HSA-392170;Reactome: R-HSA-428930;Reactome: R-HSA-418555;Reactome: R-HSA-381676;Reactome: R-HSA-416482;Reactome: R-HSA-418597;Reactome: R-HSA-202040;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-8964315;Reactome: R-HSA-400042;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-6814122;Reactome: R-HSA-4086398;Reactome: R-HSA-418592;Reactome: R-HSA-392851;Reactome: R-HSA-418594	"Glucagon-type ligand receptors";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 12";"Thromboxane signalling through TP receptor";"G alpha (s) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (12/13) signalling events";"G alpha (z) signalling events";"G-protein activation";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through BTK";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 1";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events"
XP_016999250.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017011210.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_016999354.2	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_016997701.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017003700.2	11	MetaCyc: PWY-922;MetaCyc: PWY-7560;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-5123;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7102;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-6174;Reactome: R-HSA-191273	"Mevalonate pathway I";"Methylerythritol phosphate pathway II";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Trans, trans-farnesyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Mevalonate pathway II (archaea)";"Cholesterol biosynthesis"
XP_017009464.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017008768.2	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_017013891.1	24	Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690	"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Kinesins";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"MHC class II antigen presentation";"HCMV Early Events"
XP_044249223.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017005340.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_017009355.2	2	Reactome: R-HSA-2564830;Reactome: R-HSA-5693554	"Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_017005778.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017010181.1	6	Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;MetaCyc: PWY-6952;MetaCyc: PWY-6118;MetaCyc: PWY-4261	"Synthesis of PA";"Glycerophospholipid metabolism";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Glycerol degradation I"
XP_017015197.2	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_017011387.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes"
XP_017008284.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016994298.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_017000622.2	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_044251317.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_017011153.2	8	Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8	"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism"
XP_017011135.2	12	Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-447038;MetaCyc: PWY-7221;Reactome: R-HSA-9620244	"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation"
XP_017005877.2	9	MetaCyc: PWY-6118;MetaCyc: PWY-7902;MetaCyc: PWY-7411;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94	"Glycerol-3-phosphate shuttle";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism"
XP_016999651.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_017005503.1	12	KEGG: 00520+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;Reactome: R-HSA-173599;KEGG: 00040+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00561+2.7.7.9;MetaCyc: PWY-3801	"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Glycogen synthesis";"Glycerolipid metabolism";"Sucrose degradation II (sucrose synthase)"
XP_016998778.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016996531.2	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_017009237.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_017003595.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_017009771.1	5	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-983231	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Factors involved in megakaryocyte development and platelet production"
XP_017000610.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_017005345.1	3	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis"
XP_016993082.2	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_016996624.2	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_017015595.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017014279.2	5	Reactome: R-HSA-1362409;Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-2395516	"Mitochondrial iron-sulfur cluster biogenesis";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin"
XP_044248584.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_044251329.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044250038.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044248678.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_044252158.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_017004159.2	3	KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451;MetaCyc: PWY-7856	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme a biosynthesis"
XP_017011151.2	12	Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-447038;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932	"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"NrCAM interactions";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Purine metabolism";"Synaptic adhesion-like molecules"
XP_016993945.2	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044250386.1	6	MetaCyc: PWY-6368;Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516	"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane"
XP_044249248.1	11	Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096	"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"HS-GAG degradation"
XP_016997515.2	8	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_044249320.1	14	Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167200	"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_017003061.2	6	MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism"
XP_017007175.1	18	KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053	"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Anandamide biosynthesis II"
XP_017015936.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_017008617.2	7	Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_017000450.2	5	Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-4641257	"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Protein ubiquitination";"Degradation of AXIN"
XP_016999710.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828	"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis"
XP_017002888.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_016996566.2	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_017008311.2	5	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex"
XP_017014776.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_044251169.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_017010941.2	3	Reactome: R-HSA-204174;Reactome: R-HSA-8963684;Reactome: R-HSA-156590	"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism";"Glutathione conjugation"
XP_016995773.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044250046.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016997487.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017007557.2	6	Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
XP_044251264.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_044251805.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-77387	"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Insulin receptor recycling"
XP_017003479.2	56	Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-350562	"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Degradation of AXIN";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)"
XP_017010001.2	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_044249259.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016999249.2	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_017007750.2	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_017008277.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016999074.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_017004667.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044249279.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_017007731.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044251675.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016996920.2	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_017003392.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017010323.2	8	MetaCyc: PWY-6545;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7187;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_017012987.2	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-6798695;Reactome: R-HSA-3371497	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Neutrophil degranulation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_017005768.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_044250682.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_017007581.2	14	MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5972;Reactome: R-HSA-75876	"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_017015168.2	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_016998552.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016995739.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_017012625.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_017006850.2	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_016998988.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016995612.2	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_017008724.2	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_017008874.2	6	KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-975578;MetaCyc: PWY-7426	"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_017006202.2	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_016994705.2	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_017015796.2	5	Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693	"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_044249253.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_044250469.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_044251158.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins"
XP_016994181.2	8	Reactome: R-HSA-6798695;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518	"Neutrophil degranulation";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2"
XP_017014485.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_017012509.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_017003609.2	10	Reactome: R-HSA-200425;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-163680;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Carnitine metabolism";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_017009682.2	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_017014342.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017009769.2	4	Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131	"Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis"
XP_016993988.1	4	Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_017013807.2	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_044249447.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_016992702.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017008173.2	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_044248815.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_044249964.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_016997262.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044251208.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017005119.2	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_044251378.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017005552.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_017011019.2	14	MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453	"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Stigma estolide biosynthesis"
XP_044249783.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_017007792.2	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
XP_017005733.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-450341	"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors"
XP_017008474.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_016995330.2	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_016995010.2	3	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339;Reactome: R-HSA-9609523	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_017000001.2	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_017005192.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_016999969.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016998019.2	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_044250209.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_017004601.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044252188.1	10	Reactome: R-HSA-8939243;Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-445144	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"Signal transduction by L1"
XP_016999101.2	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_016994367.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044249735.1	15	MetaCyc: PWY-5723;MetaCyc: PWY-7383;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-7218;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-6901;KEGG: 00620+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5484	"Rubisco shunt";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Purine metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_017003443.2	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_016996772.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_017001929.2	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_016993331.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Translation initiation complex formation";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_017013434.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria"
XP_017009684.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_016999889.2	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_017003360.2	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_017010797.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_017009091.2	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_016992587.2	22	Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-5675221;Reactome: R-HSA-9648025;Reactome: R-HSA-432142;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-389513;Reactome: R-HSA-6811558;Reactome: R-HSA-196299;Reactome: R-HSA-5467337	"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"Negative regulation of MAPK pathway";"EML4 and NUDC in mitotic spindle formation";"Platelet sensitization by LDL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding"
XP_017005271.2	4	Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-1170546;Reactome: R-HSA-982772	"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Prolactin receptor signaling";"Growth hormone receptor signaling"
XP_017010842.2	7	KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;MetaCyc: PWY-2301;MetaCyc: PWY-6363	"Streptomycin biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_017001842.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902	"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation"
XP_044251295.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_016998431.2	5	MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism"
XP_017008684.2	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_017010030.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_017008221.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016992614.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_017003085.1	6	Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"Mitochondrial protein import";"Photosynthesis";"ATP biosynthesis";"Cristae formation"
XP_016992819.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_017004997.2	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_017011879.2	10	Reactome: R-HSA-3000171;MetaCyc: PWY-5691;MetaCyc: PWY-7394;Reactome: R-HSA-975634;Reactome: R-HSA-2453864;Reactome: R-HSA-977225;KEGG: 00230+3.5.2.17;Reactome: R-HSA-6798695;MetaCyc: PWY-7849;Reactome: R-HSA-2453902	"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin I";"Urate conversion to allantoin II";"Retinoid metabolism and transport";"Retinoid cycle disease events";"Amyloid fiber formation";"Purine metabolism";"Neutrophil degranulation";"Urate conversion to allantoin III";"The canonical retinoid cycle in rods (twilight vision)"
XP_017001020.1	83	Reactome: R-HSA-391160;Reactome: R-HSA-9607240;Reactome: R-HSA-5654695;Reactome: R-HSA-5654720;Reactome: R-HSA-8851805;Reactome: R-HSA-8983432;Reactome: R-HSA-5654693;Reactome: R-HSA-2424491;Reactome: R-HSA-5655302;Reactome: R-HSA-180292;Reactome: R-HSA-1963642;Reactome: R-HSA-912526;Reactome: R-HSA-9634285;Reactome: R-HSA-2871796;Reactome: R-HSA-74751;Reactome: R-HSA-5654733;Reactome: R-HSA-186763;Reactome: R-HSA-179812;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-354194;Reactome: R-HSA-2179392;Reactome: R-HSA-9034864;Reactome: R-HSA-109704;Reactome: R-HSA-8856825;Reactome: R-HSA-5654726;Reactome: R-HSA-1433557;Reactome: R-HSA-5673001;Reactome: R-HSA-8853334;Reactome: R-HSA-983695;Reactome: R-HSA-8853338;Reactome: R-HSA-1839117;Reactome: R-HSA-8851907;Reactome: R-HSA-5654699;Reactome: R-HSA-9645135;Reactome: R-HSA-912631;Reactome: R-HSA-2428933;Reactome: R-HSA-5637810;Reactome: R-HSA-2029482;Reactome: R-HSA-1963640;Reactome: R-HSA-1295596;Reactome: R-HSA-5654689;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-5654688;Reactome: R-HSA-512988;Reactome: R-HSA-210993;Reactome: R-HSA-389359;Reactome: R-HSA-167044;Reactome: R-HSA-5654712;Reactome: R-HSA-8875555;Reactome: R-HSA-9664565;Reactome: R-HSA-5663213;Reactome: R-HSA-8875656;Reactome: R-HSA-5655291;Reactome: R-HSA-8853659;Reactome: R-HSA-180336;Reactome: R-HSA-9026519;Reactome: R-HSA-8865999;Reactome: R-HSA-5654719;Reactome: R-HSA-5654710;Reactome: R-HSA-1257604;Reactome: R-HSA-1433559;Reactome: R-HSA-5654732;Reactome: R-HSA-112412;Reactome: R-HSA-9027284;Reactome: R-HSA-388841;Reactome: R-HSA-5654706;Reactome: R-HSA-5655253;Reactome: R-HSA-6807004;Reactome: R-HSA-1236382;Reactome: R-HSA-5654727;Reactome: R-HSA-2730905;Reactome: R-HSA-5654700;Reactome: R-HSA-9028731;Reactome: R-HSA-375165;Reactome: R-HSA-8856828;Reactome: R-HSA-2871809;Reactome: R-HSA-1250347;Reactome: R-HSA-5654704;Reactome: R-HSA-74749;Reactome: R-HSA-1250196;Reactome: R-HSA-9028335	"Signal regulatory protein family interactions";"FLT3 Signaling";"PI-3K cascade:FGFR2";"PI-3K cascade:FGFR4";"MET activates RAS signaling";"Interleukin-15 signaling";"FRS-mediated FGFR1 signaling";"DAP12 signaling";"Signaling by FGFR1 in disease";"GAB1 signalosome";"PI3K events in ERBB2 signaling";"Interleukin receptor SHC signaling";"Constitutive Signaling by Overexpressed ERBB2";"FCERI mediated MAPK activation";"Insulin receptor signalling cascade";"Negative regulation of FGFR4 signaling";"Downstream signal transduction";"GRB2 events in EGFR signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"EGFR Transactivation by Gastrin";"Activated NTRK3 signals through RAS";"PI3K Cascade";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of FGFR1 signaling";"Signaling by SCF-KIT";"RAF/MAP kinase cascade";"Signaling by FGFR3 fusions in cancer";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Signaling by FGFR3 point mutants in cancer";"Signaling by cytosolic FGFR1 fusion mutants";"MET activates PI3K/AKT signaling";"SHC-mediated cascade:FGFR2";"STAT5 Activation";"Regulation of signaling by CBL";"SHC-related events triggered by IGF1R";"Constitutive Signaling by EGFRvIII";"Regulation of actin dynamics for phagocytic cup formation";"GRB2 events in ERBB2 signaling";"Spry regulation of FGF signaling";"PI-3K cascade:FGFR1";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC-mediated cascade:FGFR1";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Tie2 Signaling";"CD28 dependent Vav1 pathway";"Signalling to RAS";"FRS-mediated FGFR4 signaling";"MET activates RAP1 and RAC1";"Signaling by ERBB2 KD Mutants";"RHO GTPases Activate WASPs and WAVEs";"MET receptor recycling";"Signaling by FGFR4 in disease";"RET signaling";"SHC1 events in EGFR signaling";"Activated NTRK2 signals through RAS";"MET activates PTPN11";"SHC-mediated cascade:FGFR4";"PI-3K cascade:FGFR3";"PIP3 activates AKT signaling";"Regulation of KIT signaling";"Negative regulation of FGFR3 signaling";"SOS-mediated signalling";"Erythropoietin activates RAS";"Costimulation by the CD28 family";"FRS-mediated FGFR3 signaling";"Signaling by FGFR2 in disease";"Negative regulation of MET activity";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Negative regulation of FGFR2 signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"FRS-mediated FGFR2 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"NCAM signaling for neurite out-growth";"Clathrin-mediated endocytosis";"FCERI mediated Ca+2 mobilization";"SHC1 events in ERBB4 signaling";"SHC-mediated cascade:FGFR3";"Signal attenuation";"SHC1 events in ERBB2 signaling";"Activated NTRK2 signals through PI3K"
XP_017002641.2	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_017012170.2	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_017015019.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044250586.1	11	Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-5693565;Reactome: R-HSA-2029482;Reactome: R-HSA-5685938;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8939236;Reactome: R-HSA-525793;Reactome: R-HSA-69231;Reactome: R-HSA-8940973;Reactome: R-HSA-428890	"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of actin dynamics for phagocytic cup formation";"HDR through Single Strand Annealing (SSA)";"T cell receptor signaling pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myogenesis";"Cyclin D associated events in G1";"RUNX2 regulates osteoblast differentiation";"Role of ABL in ROBO-SLIT signaling"
XP_044252154.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_017005163.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_017012707.2	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_044251139.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_017008562.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_017005303.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_044251837.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_017012893.2	5	KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_016992519.2	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_017013731.2	10	Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096	"MPS VII - Sly syndrome";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Sphingolipid metabolism";"Galactose metabolism";"Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"HS-GAG degradation"
XP_017013148.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_017004788.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs"
XP_017013808.2	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_016995477.2	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_016997127.2	11	Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells"
XP_016997048.2	12	MetaCyc: PWY-5278;Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25;Reactome: R-HSA-2408550;KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-6932;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00920+2.7.1.25;KEGG: 00920+2.7.7.4	"Sulfite oxidation III";"Transport and synthesis of PAPS";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenocompound metabolism";"Monobactam biosynthesis";"Selenate reduction";"Sulfate activation for sulfonation";"Purine metabolism";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Sulfur metabolism"
XP_016997787.2	4	MetaCyc: PWY-6129;Reactome: R-HSA-4755609;KEGG: 00900+2.5.1.87;Reactome: R-HSA-446199	"Dolichol and dolichyl phosphate biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Terpenoid backbone biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_017004334.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-8939243	"Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_017004774.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_017003678.2	14	Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-113418	"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex"
XP_016997282.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016995423.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_044248834.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_017009775.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_017003439.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016992767.2	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_017001677.2	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_017005911.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017000082.2	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_017012013.2	22	MetaCyc: PWY-6958;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-5353;MetaCyc: PWY-7049;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7726;MetaCyc: PWY-7035;MetaCyc: PWY-7727;MetaCyc: PWY-7728;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7606;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7592;Reactome: R-HSA-75876;MetaCyc: PWY-6598	"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis"
XP_017009998.2	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_017012986.2	11	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-69166;Reactome: R-HSA-5693568;Reactome: R-HSA-174437;Reactome: R-HSA-6804756	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Removal of the Flap Intermediate from the C-strand";"Regulation of TP53 Activity through Phosphorylation"
XP_017000440.2	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_017002517.2	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_016999218.2	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_017011346.2	8	MetaCyc: PWY-7922;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)"
XP_017007242.2	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_017007602.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_017006596.2	4	KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051	"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I"
XP_044251223.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_017009881.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_017015003.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_017005825.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016998252.2	5	Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920	"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability"
XP_017006894.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_017004991.2	14	MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199	"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation"
XP_017011084.1	20	MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-7574;MetaCyc: PWY-7858;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7340;MetaCyc: PWY-735;MetaCyc: PWY-7291;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7007;MetaCyc: PWY-7288	"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)"
XP_016995597.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_017007799.2	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_017013935.2	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-1834949	"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA"
XP_044248697.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_017012514.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_017011786.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_017004351.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017009455.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090	"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures"
XP_017010380.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_016999512.1	6	Reactome: R-HSA-76005;Reactome: R-HSA-418597;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-5099900	"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4"
XP_017004344.2	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_016997518.2	9	Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events"
XP_017014995.2	3	Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508	"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_017013248.2	3	KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426;Reactome: R-HSA-975574	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway"
XP_017002154.2	8	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-165159	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"mTOR signalling"
XP_016992484.2	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_017007536.2	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_044251997.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_017010787.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_017005186.2	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_044249456.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_017003366.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044249758.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_017016238.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_017013605.2	3	Reactome: R-HSA-2995383;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766	"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown"
XP_016996122.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_017012936.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_017000801.2	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_044250663.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016998888.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_017010346.2	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_044249181.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_044249487.1	42	Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-1912408;Reactome: R-HSA-3214842;Reactome: R-HSA-5617472;Reactome: R-HSA-977225;Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-110329;Reactome: R-HSA-5625886;Reactome: R-HSA-9610379;Reactome: R-HSA-2559580;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-606279;Reactome: R-HSA-110328;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-3214858;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-5578749;Reactome: R-HSA-8939236;Reactome: R-HSA-3214841;Reactome: R-HSA-5693607;Reactome: R-HSA-912446;Reactome: R-HSA-427389;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-9616222;Reactome: R-HSA-171306;Reactome: R-HSA-8936459;Reactome: R-HSA-9609690;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-212300	"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Pre-NOTCH Transcription and Translation";"HDMs demethylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Amyloid fiber formation";"Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HCMV Late Events";"Oxidative Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"RMTs methylate histone arginines";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"DNA methylation";"Estrogen-dependent gene expression";"Transcriptional regulation by small RNAs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PKMTs methylate histone lysines";"Processing of DNA double-strand break ends";"Meiotic recombination";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"Transcriptional regulation of granulopoiesis";"Packaging Of Telomere Ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Early Events";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"PRC2 methylates histones and DNA"
XP_017005390.2	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_017012807.2	3	Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5	"Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation"
XP_017013147.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_017015544.2	37	Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-5663220;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-204005;Reactome: R-HSA-2500257;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-9639288;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-141444;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-2467813;Reactome: R-HSA-9610379;Reactome: R-HSA-165054	"snRNP Assembly";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"RHO GTPases Activate Formins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"COPII-mediated vesicle transport";"Resolution of Sister Chromatid Cohesion";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"Amino acids regulate mTORC1";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Separation of Sister Chromatids";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA"
XP_044251690.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_017012269.2	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_016998507.2	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_017012795.2	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_017008233.2	2	Reactome: R-HSA-8856828;Reactome: R-HSA-5627123	"Clathrin-mediated endocytosis";"RHO GTPases activate PAKs"
XP_016997140.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017006665.2	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_044248778.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_017012466.2	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_017012172.2	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_017002976.2	14	MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7619	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis"
XP_044248706.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016997812.1	29	Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-75953	"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation"
XP_017008411.2	6	Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-428930	"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor"
XP_017003032.2	30	Reactome: R-HSA-69231;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-2565942;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-917937;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-400253;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-2122947;Reactome: R-HSA-187577;Reactome: R-HSA-5684264;Reactome: R-HSA-2644607;Reactome: R-HSA-1169091;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-1170546;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837	"Cyclin D associated events in G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Regulation of PLK1 Activity at G2/M Transition";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Iron uptake and transport";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"Circadian Clock";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"NOTCH1 Intracellular Domain Regulates Transcription";"SCF(Skp2)-mediated degradation of p27/p21";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Activation of NF-kappaB in B cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Prolactin receptor signaling";"Neddylation";"FCERI mediated NF-kB activation"
XP_017007849.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs"
XP_017003538.2	8	Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;MetaCyc: PWY-6611	"Purine salvage";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine metabolism";"Surfactant metabolism";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V"
XP_017001021.1	83	Reactome: R-HSA-375165;Reactome: R-HSA-9028731;Reactome: R-HSA-5654700;Reactome: R-HSA-2730905;Reactome: R-HSA-1250347;Reactome: R-HSA-2871809;Reactome: R-HSA-8856828;Reactome: R-HSA-74749;Reactome: R-HSA-5654704;Reactome: R-HSA-9028335;Reactome: R-HSA-1250196;Reactome: R-HSA-5654706;Reactome: R-HSA-5655253;Reactome: R-HSA-5654727;Reactome: R-HSA-1236382;Reactome: R-HSA-6807004;Reactome: R-HSA-180336;Reactome: R-HSA-5655291;Reactome: R-HSA-8853659;Reactome: R-HSA-8875656;Reactome: R-HSA-1257604;Reactome: R-HSA-5654710;Reactome: R-HSA-5654719;Reactome: R-HSA-8865999;Reactome: R-HSA-9026519;Reactome: R-HSA-112412;Reactome: R-HSA-5654732;Reactome: R-HSA-1433559;Reactome: R-HSA-388841;Reactome: R-HSA-9027284;Reactome: R-HSA-389359;Reactome: R-HSA-512988;Reactome: R-HSA-210993;Reactome: R-HSA-2219530;Reactome: R-HSA-5654688;Reactome: R-HSA-6811558;Reactome: R-HSA-5654689;Reactome: R-HSA-167044;Reactome: R-HSA-8875555;Reactome: R-HSA-5654712;Reactome: R-HSA-5663213;Reactome: R-HSA-9664565;Reactome: R-HSA-8851907;Reactome: R-HSA-1839117;Reactome: R-HSA-8853334;Reactome: R-HSA-983695;Reactome: R-HSA-8853338;Reactome: R-HSA-1433557;Reactome: R-HSA-5673001;Reactome: R-HSA-2428933;Reactome: R-HSA-912631;Reactome: R-HSA-9645135;Reactome: R-HSA-5654699;Reactome: R-HSA-1295596;Reactome: R-HSA-1963640;Reactome: R-HSA-2029482;Reactome: R-HSA-5637810;Reactome: R-HSA-179812;Reactome: R-HSA-5654733;Reactome: R-HSA-186763;Reactome: R-HSA-74751;Reactome: R-HSA-2179392;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-354194;Reactome: R-HSA-9034864;Reactome: R-HSA-109704;Reactome: R-HSA-8856825;Reactome: R-HSA-5654726;Reactome: R-HSA-2424491;Reactome: R-HSA-5655302;Reactome: R-HSA-180292;Reactome: R-HSA-1963642;Reactome: R-HSA-9634285;Reactome: R-HSA-912526;Reactome: R-HSA-2871796;Reactome: R-HSA-5654695;Reactome: R-HSA-9607240;Reactome: R-HSA-391160;Reactome: R-HSA-5654720;Reactome: R-HSA-8851805;Reactome: R-HSA-5654693;Reactome: R-HSA-8983432	"NCAM signaling for neurite out-growth";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR2 signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"SHC1 events in ERBB4 signaling";"FCERI mediated Ca+2 mobilization";"Clathrin-mediated endocytosis";"Signal attenuation";"SHC-mediated cascade:FGFR3";"Activated NTRK2 signals through PI3K";"SHC1 events in ERBB2 signaling";"FRS-mediated FGFR3 signaling";"Signaling by FGFR2 in disease";"Negative regulation of FGFR2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Negative regulation of MET activity";"SHC1 events in EGFR signaling";"Signaling by FGFR4 in disease";"RET signaling";"MET receptor recycling";"PIP3 activates AKT signaling";"PI-3K cascade:FGFR3";"SHC-mediated cascade:FGFR4";"MET activates PTPN11";"Activated NTRK2 signals through RAS";"SOS-mediated signalling";"Negative regulation of FGFR3 signaling";"Regulation of KIT signaling";"Costimulation by the CD28 family";"Erythropoietin activates RAS";"CD28 dependent Vav1 pathway";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Tie2 Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC-mediated cascade:FGFR1";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI-3K cascade:FGFR1";"Signalling to RAS";"MET activates RAP1 and RAC1";"FRS-mediated FGFR4 signaling";"RHO GTPases Activate WASPs and WAVEs";"Signaling by ERBB2 KD Mutants";"MET activates PI3K/AKT signaling";"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR3 fusions in cancer";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Signaling by FGFR3 point mutants in cancer";"Signaling by SCF-KIT";"RAF/MAP kinase cascade";"SHC-related events triggered by IGF1R";"Regulation of signaling by CBL";"STAT5 Activation";"SHC-mediated cascade:FGFR2";"Spry regulation of FGF signaling";"GRB2 events in ERBB2 signaling";"Regulation of actin dynamics for phagocytic cup formation";"Constitutive Signaling by EGFRvIII";"GRB2 events in EGFR signaling";"Negative regulation of FGFR4 signaling";"Downstream signal transduction";"Insulin receptor signalling cascade";"EGFR Transactivation by Gastrin";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Activated NTRK3 signals through RAS";"PI3K Cascade";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of FGFR1 signaling";"DAP12 signaling";"Signaling by FGFR1 in disease";"GAB1 signalosome";"PI3K events in ERBB2 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Interleukin receptor SHC signaling";"FCERI mediated MAPK activation";"PI-3K cascade:FGFR2";"FLT3 Signaling";"Signal regulatory protein family interactions";"PI-3K cascade:FGFR4";"MET activates RAS signaling";"FRS-mediated FGFR1 signaling";"Interleukin-15 signaling"
XP_017013495.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016994898.2	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_044248687.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_017005281.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_017014626.2	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_017007881.2	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_044248616.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_017000148.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_017003193.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_017009845.2	30	Reactome: R-HSA-69231;Reactome: R-HSA-8854050;Reactome: R-HSA-2565942;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-917937;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-400253;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-2122947;Reactome: R-HSA-187577;Reactome: R-HSA-5684264;Reactome: R-HSA-2644607;Reactome: R-HSA-1169091;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-1170546;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837	"Cyclin D associated events in G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Iron uptake and transport";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"Circadian Clock";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"NOTCH1 Intracellular Domain Regulates Transcription";"SCF(Skp2)-mediated degradation of p27/p21";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Activation of NF-kappaB in B cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Prolactin receptor signaling";"Neddylation";"FCERI mediated NF-kB activation"
XP_017014873.2	3	Reactome: R-HSA-191859;Reactome: R-HSA-3214858;Reactome: R-HSA-6804760	"snRNP Assembly";"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation"
XP_044252190.1	10	Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-445144;Reactome: R-HSA-1483191	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"Signal transduction by L1";"Synthesis of PC"
XP_044251225.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_016994522.2	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_017010693.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_017013324.2	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_017009817.2	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_017013531.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_017006218.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902	"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation"
XP_017008054.1	3	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843	"Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_044251986.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_017005316.1	2	Reactome: R-HSA-8876725;Reactome: R-HSA-611105	"Protein methylation";"Respiratory electron transport"
XP_017010718.2	24	Reactome: R-HSA-2871837;Reactome: R-HSA-5625740;Reactome: R-HSA-202424;Reactome: R-HSA-6804757;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5607764;KEGG: 05170+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-2730905;Reactome: R-HSA-389357;Reactome: R-HSA-165158;Reactome: R-HSA-114604;Reactome: R-HSA-444257;Reactome: R-HSA-5218920;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1257604;KEGG: 04151+2.7.11.1	"FCERI mediated NF-kB activation";"RHO GTPases activate PKNs";"Downstream TCR signaling";"Regulation of TP53 Degradation";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"Relaxin signaling pathway";"Thermogenesis";"Integrin signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"mTOR signaling pathway";"CLEC7A (Dectin-1) signaling";"Human immunodeficiency virus 1 infection";"G beta:gamma signalling through PI3Kgamma";"Role of LAT2/NTAL/LAB on calcium mobilization";"CD28 dependent PI3K/Akt signaling";"Activation of AKT2";"GPVI-mediated activation cascade";"RSK activation";"VEGFR2 mediated vascular permeability";"Human papillomavirus infection";"PIP3 activates AKT signaling";"PI3K-Akt signaling pathway"
XP_016998242.2	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_017008465.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-434316	"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_017008807.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_017009248.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_017013934.2	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_017006941.2	5	Reactome: R-HSA-110328;Reactome: R-HSA-9630221;Reactome: R-HSA-110357;Reactome: R-HSA-9630222;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate processing";"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate binding";"Cleavage of the damaged pyrimidine"
XP_017010236.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_017001362.2	6	Reactome: R-HSA-416993;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Trafficking of GluR2-containing AMPA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_017006383.2	12	MetaCyc: PWY-801;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-601;MetaCyc: PWY-1187;MetaCyc: PWY-2821;Reactome: R-HSA-71240;MetaCyc: PWY-7901;KEGG: 00270+4.4.1.13;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6936;MetaCyc: PWY-6309	"Homocysteine and cysteine interconversion";"Selenocompound metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from phenylalanine";"Tryptophan catabolism";"Glucosinolate biosynthesis from tyrosine";"Cysteine and methionine metabolism";"Tryptophan metabolism";"Seleno-amino acid biosynthesis (plants)";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_017015880.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_017006044.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_044251821.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_044249648.1	42	Reactome: R-HSA-69473;Reactome: R-HSA-3214858;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-977225;Reactome: R-HSA-1221632;Reactome: R-HSA-110329;Reactome: R-HSA-9610379;Reactome: R-HSA-5625886;Reactome: R-HSA-1912408;Reactome: R-HSA-3214842;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-8936459;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-5693607;Reactome: R-HSA-912446;Reactome: R-HSA-427389;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-8939236;Reactome: R-HSA-3214841;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519	"G2/M DNA damage checkpoint";"RMTs methylate histone arginines";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"Amyloid fiber formation";"Meiotic synapsis";"Cleavage of the damaged pyrimidine";"HCMV Late Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Pre-NOTCH Transcription and Translation";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"PRC2 methylates histones and DNA";"HCMV Early Events";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"Processing of DNA double-strand break ends";"Meiotic recombination";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PKMTs methylate histone lysines";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"DNA methylation";"Estrogen-dependent gene expression"
XP_016998030.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_044248583.1	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_017007692.2	3	Reactome: R-HSA-5617472;Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_017013304.2	8	MetaCyc: PWY-4983;MetaCyc: PWY-5154;KEGG: 00250+4.3.2.1;KEGG: 00220+4.3.2.1;MetaCyc: PWY-4984;MetaCyc: PWY-5;MetaCyc: PWY-7400;Reactome: R-HSA-70635	"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Urea cycle";"Canavanine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Urea cycle"
XP_017002205.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016996977.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_017003607.2	10	Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-200425;Reactome: R-HSA-6804756;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-163680	"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Carnitine metabolism";"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity"
XP_017006058.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"G-protein activation";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_016997318.2	1	Reactome: R-HSA-916853	"Degradation of GABA"
XP_016993348.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_017010885.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_017005023.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_016992906.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_017005335.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_044248708.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044249255.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_044249471.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_017002560.2	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473	"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint"
XP_016996244.2	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_016997582.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_016993766.2	6	Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-5545483;Reactome: R-HSA-5632987;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"Defective Mismatch Repair Associated With MLH1";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes"
XP_017004186.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017011510.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_017004260.2	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_017010648.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016993381.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_017008303.2	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_016995360.2	5	Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
XP_016995300.2	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_016996405.2	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_017003183.1	14	Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569	"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_017007652.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_017000869.2	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_017005322.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044251288.1	4	Reactome: R-HSA-8875555;Reactome: R-HSA-186763;Reactome: R-HSA-8875656;Reactome: R-HSA-912631	"MET activates RAP1 and RAC1";"Downstream signal transduction";"MET receptor recycling";"Regulation of signaling by CBL"
XP_017003916.2	14	KEGG: 00190+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-6969;Reactome: R-HSA-611105;KEGG: 00650+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-561;KEGG: 00020+1.3.5.1	"Oxidative phosphorylation";"Carbon fixation pathways in prokaryotes";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Respiratory electron transport";"Butanoate metabolism";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)"
XP_016997516.2	9	Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042	"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_017012546.1	8	Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-432040	"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_016993714.2	3	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes"
XP_017015795.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016994694.2	3	MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism"
XP_016994646.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016994603.2	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_017013095.2	3	MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757	"Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines"
XP_017008882.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_017015817.2	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_016999942.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379	"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events"
XP_044251673.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_017005209.2	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096	"MPS I - Hurler syndrome";"CS/DS degradation";"HS-GAG degradation"
XP_017006267.2	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_044248747.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044252116.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_017006893.2	2	Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100	"Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis"
XP_016997726.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_017004369.2	4	Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22	"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism"
XP_017001012.2	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_044249942.1	56	Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858	"Separation of Sister Chromatids";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity"
XP_017014853.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_017009564.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016999346.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_017012298.2	13	MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-7254;MetaCyc: PWY-8086;KEGG: 00020+4.2.1.2;Reactome: R-HSA-71403;KEGG: 00620+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-5913;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-6969;MetaCyc: PWY-5392	"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"TCA cycle VII (acetate-producers)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II"
XP_016998241.2	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_016994383.2	17	Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-69473;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-1834949;Reactome: R-HSA-6804756;Reactome: R-HSA-5685939	"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"G2/M DNA damage checkpoint";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Processing of DNA double-strand break ends";"Cytosolic sensors of pathogen-associated DNA";"Regulation of TP53 Activity through Phosphorylation";"HDR through MMEJ (alt-NHEJ)"
XP_017008066.2	2	Reactome: R-HSA-4085011;Reactome: R-HSA-4085001	"Defective GNE causes sialuria, Nonaka myopathy and inclusion body myopathy 2";"Sialic acid metabolism"
XP_017009911.2	57	Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257	"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Degradation of AXIN"
XP_017015895.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"